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American Heart Journal

Hoang V Tran, Arlene S Ash, Joel M Gore, Chad E Darling, Catarina I Kiefe, Robert J Goldberg
BACKGROUND: Long-term trends in the incidence rates (IRs) and hospital case-fatality rates (CFRs) of ventricular tachycardia (VT) and ventricular fibrillation (VF) among patients hospitalized with acute myocardial infarction (AMI) have not been recently examined. METHODS: We used data from 11,825 patients hospitalized with AMI at all 11 medical centers in central Massachusetts on a biennial basis between 1986 and 2011. Multivariable adjusted logistic regression modeling was used to examine trends in hospital IRs and CFRs of VT and VF complicating AMI...
November 1, 2018: American Heart Journal
Ameenathul M Fawzy, Brian Olshansky, Gregory Y H Lip
No abstract text is available yet for this article.
October 31, 2018: American Heart Journal
Alexander C Perino, George C Leef, Andrew Cluckey, Fahd N Yunus, Mariam Askari, Paul A Heidenreich, Sanjiv M Narayan, Paul J Wang, Mintu P Turakhia
BACKGROUND: Approaches, tools, and technologies for atrial fibrillation (AF) ablation have evolved significantly since its inception. We sought to characterize secular trends in AF ablation success rates. METHODS: We performed a systematic review and meta-analysis of AF ablation from January 1, 1990, to August 1, 2016, searching PubMed, Scopus, and Cochrane databases. Major exclusion criteria were insufficient outcome reporting and ablation strategies that were not prespecified and uniform...
October 29, 2018: American Heart Journal
William J Davison, Phyo Kyaw Myint, Allan B Clark, John F Potter
BACKGROUND: Guidelines recommend ambulatory or home blood pressure monitoring to improve hypertension diagnosis and monitoring. Both these methods are ascribed the same threshold values, but whether they produce similar results has not been established in certain patient groups. METHODS: Adults with mild/moderate stroke or transient ischemic attack (N = 80) completed 2 sets of ambulatory and home blood pressure monitoring. Systolic and diastolic blood pressure values from contemporaneous measurements were compared, and the limits of agreement were assessed...
October 19, 2018: American Heart Journal
Maria Julia Machline-Carrion, Rafael Marques Soares, Lucas Petri Damiani, Viviane Bezerra Campos, Bruna Sampaio, Juliana Yamashita, Francisco H Fonseca, Maria Cristina Izar, Celso Amodeo, Octavio Marques Pontes-Neto, Pedro Gabriel de Melo Barros, Renato D Lopes, Nilton Brandão da Silva, Hélio Penna Guimarães, Leopoldo Piegas, Airton T Stein, Otavio Berwanger
BACKGROUND: Translating evidence into clinical practice in the management of high cardiovascular risk patients is challenging. Few quality improvement interventions have rigorously evaluated their impact on both patient care and clinical outcomes. OBJECTIVES: The main objectives are to evaluate the impact of a multifaceted educational intervention on adherence to local guidelines for the prescription of statins, antiplatelets and angiotensin converting enzyme inhibitors or angiotensin II receptor blockers for high cardiovascular risk patients, as well as on the incidence of major cardiovascular events...
October 17, 2018: American Heart Journal
Jason G Andrade, Jean Champagne, Marc W Deyell, Vidal Essebag, Sandra Lauck, Carlos Morillo, John Sapp, Alan Skanes, Patricia Theoret-Patrick, George A Wells, Atul Verma
BACKGROUND: The ideal management of patients with newly diagnosed symptomatic atrial fibrillation (AF) remains unknown. Current practice guidelines recommend a trial of antiarrhythmic drugs (AAD) prior to considering an invasive ablation procedure. However, earlier ablation offers an opportunity to halt the progressive patho-anatomical changes associated with AF, as well as impart other important clinical benefits. OBJECTIVE: The aim of this study is to determine the optimal initial management strategy for patients with newly diagnosed, symptomatic atrial fibrillation...
October 17, 2018: American Heart Journal
Sean C Beinart, Andrea Natale, Atul Verma, Alpesh Amin, Scott Kasner, Hans-Cristoph Diener, Maurizio Del Greco, Bruce L Wilkoff, Erika Pouliot, Noreli Franco, Suneet Mittal
BACKGROUND: Traditionally, insertable cardiac monitor (ICM) procedures have been performed in the cardiac catheterization (CATH) or electrophysiology (EP) laboratory. The introduction of the miniaturized Reveal LINQ ICM has led to simplified and less invasive procedures, affording hospitals flexibility in planning where these procedures occur without compromising patient safety or outcomes. METHODS: The present analysis of the ongoing, prospective, observational, multicenter Reveal LINQ Registry sought to provide real-world feasibility and safety data regarding the ICM procedure performed in the CATH/EP lab or operating room and to compare it with insertions performed outside of these traditional hospital settings...
October 14, 2018: American Heart Journal
Blandine Mondésert, Jamil Bashir, François Philippon, Marc Dubuc, Guy Amit, Derek Exner, Jacqueline Joza, David H Birnie, Chris Lane, Bernice Tsang, Victoria Korley, Danna Spears, Andrea Ling, Angie Djuric, Eugene Crystal, Tom Hruczkowski, Jean-François Roux, Sandra Carroll, Vidal Essebag, Andrew D Krahn, Jeff S Healey
BACKGROUND: The defibrillator lead is the weakest part of the transvenous (TV) implantable cardioverter defibrillation (ICD) system and a frequent cause of morbidity. Lead dislodgement, cardiac perforation, insertion-related trauma including pneumothorax and vascular injury, are common early complications of TV-ICD implantation. Venous occlusion, tricuspid valve dysfunction, lead fracture and lead insulation failure are additional, later complications. The introduction of a totally sub-cutaneous ICD (S-ICD) may reduce these lead-related issues, patient morbidity, hospitalizations and costs...
October 9, 2018: American Heart Journal
Srinath Adusumalli, Bram J Geller, Lin Yang, Jay Giri, Peter W Groeneveld
No abstract text is available yet for this article.
October 2, 2018: American Heart Journal
Neha J Pagidipati, Daniel W Mudrick, Karen Chiswell, Amanda Brucker, Eric D Peterson, Pamela S Douglas
BACKGROUND: Patients with nonobstructive coronary artery disease (CAD) have worse outcomes compared with those without CAD; however, few studies have compared the intermediate- and long-term impact of CAD severity as a function of patient sex. METHODS: We evaluated 5-year and long-term all-cause mortality of women and men undergoing elective coronary angiography at a single center by degree of CAD: no CAD (1%-24% stenosis), nonobstructive CAD (25%-69% epicardial stenosis or 25%-49% left main stenosis), or obstructive CAD (epicardial stenosis ≥70% or left main stenosis ≥50%), both overall and after adjusting for baseline clinical risk factors using Cox proportional-hazards models...
October 2, 2018: American Heart Journal
Maria Julia Machline-Carrion, Eliana Vieira Santucci, Lucas Petri Damiani, Cecilia Bahit, Germán Málaga, Octávio Marques Pontes-Neto, Sheila Cristina Ouriques Martins, Viviane Flumignan Zétola, Karina Normilio-Silva, Gabriel Rodrigues de Freitas, Alessandra Gorgulho, Antônio De Salles, Beatriz Gonzales Pacheco da Silva, Juliana Yamashita Santos, Isabella de Andrade Jesuíno, Priscila Regina Torres Bueno, Alexandre Biasi Cavalcanti, Hélio Penna Guimarães, Ying Xian, Janet Prvu Bettger, Renato D Lopes, Eric D Peterson, Otávio Berwanger
BACKGROUND: Translating evidence into clinical practice in the management of acute ischemic stroke (AIS) and transient ischemic attack (TIA) is challenging especially in low- and middle-income countries. OBJECTIVES: The aim of this study is to assess the effect of a multifaceted quality improvement intervention on adherence to evidence-based therapies for AIS and TIA patients care. DESIGN: We designed a pragmatic, 2-arm cluster-randomized trial involving 36 clusters and 1624 patients from Brazil, Argentina, and Peru...
September 30, 2018: American Heart Journal
Liliya Benchetrit, Chloe Zimmerman, Haikun Bao, Kumar Dharmarajan, Faseeha Altaf, Jeph Herrin, Zhenqiu Lin, Harlan M Krumholz, Elizabeth E Drye, Kasia J Lipska, Erica S Spatz
BACKGROUND: A key quality metric for Accountable Care Organizations (ACOs) is the rate of hospitalization among patients with heart failure (HF). Among this patient population, non-HF-related hospitalizations account for a substantial proportion of admissions. Understanding the types of admissions and the distribution of admission types across ACOs of varying performance may provide important insights for lowering admission rates. METHODS: We examined admission diagnoses among 220 Medicare Shared Savings Program ACOs in 2013...
September 30, 2018: American Heart Journal
William Eysenck, Jet van Zalen, Nick Freemantle, Guy Lloyd, Steve Furniss, Neil Sulke
A central iliac arteriovenous anastomosis, the 'coupler' (ROX Medical, California, USA) results in a significant reduction in blood pressure in hypertensive patients. This study assessed the change in AF burden following coupler implantation in patients with paroxysmal AF (PAF) and hypertension. Good blood pressure control using the coupler results in a significant reduction in AF burden.
September 29, 2018: American Heart Journal
Alexander C Egbe, William R Miranda, Sameh M Said, Sorin V Pislaru, Patricia A Pellikka, Barry A Borlaug, Srikanth Kothapalli, Heidi M Connolly
BACKGROUND: To determine if RV volume was predictive of survival and cardiovascular adverse event (CAE) after pulmonary valve replacement (PVR). METHODS: We reviewed the MACHD (Mayo Adult Congenital Heart Disease) database for patients with tetralogy of Fallot (TOF) undergoing PVR, 2000-2015. The patients were divided into quartiles based on RV end-diastolic volume index (RVEDVI); those in the lowest quartile (Group A, n = 46) and the top quartile (Group B, n = 42) were selected as the study cohort...
September 29, 2018: American Heart Journal
Aruna D Pradhan, Nina P Paynter, Brendan M Everett, Robert J Glynn, Pierre Amarenco, Marshall Elam, Henry Ginsberg, William R Hiatt, Shun Ishibashi, Wolfgang Koenig, Børge G Nordestgaard, Jean-Charles Fruchart, Peter Libby, Paul M Ridker
Observational, genetic, and experimental data indicate that triglyceride rich lipoproteins (TRLs) likely participate causally in atherothrombosis. Yet, robust clinical trial evidence that triglyceride (TG) lowering therapy reduces cardiovascular events remains elusive. The selective peroxisome proliferator-activated receptor alpha modulator (SPPARM-α), pemafibrate, will be used to target residual cardiovascular risk remaining after treatment to reduce low-density lipoprotein cholesterol (LDL-C) in individuals with the dyslipidemia of type 2 diabetes mellitus (T2)...
September 29, 2018: American Heart Journal
Michael Dandel, Roland Hetzer
By reduction of ventricular wall-tension and improving the blood supply to vital organs, ventricular assist devices (VADs) can eliminate the major pathophysiological stimuli for cardiac remodeling and even induce reverse remodeling occasionally accompanied by clinically relevant reversal of cardiac structural and functional alterations allowing VAD explantation, even if the underlying cause for the heart failure (HF) was dilated cardiomyopathy. Accordingly, a tempting potential indication for VADs in the future might be their elective implantation as a therapeutic strategy to promote cardiac recovery in earlier stages of HF, when the reversibility of morphological and functional alterations is higher...
September 17, 2018: American Heart Journal
Leah L Zullig, Lisa Egbuonu-Davis, Anjali Trasy, Christiana Oshotse, Karen M Goldstein, Hayden B Bosworth
No abstract text is available yet for this article.
September 14, 2018: American Heart Journal
Paul Guedeney, Usman Baber, Bimmer Claessen, Melissa Aquino, Anton Camaj, Sabato Sorrentino, Birgit Vogel, Serdar Farhan, Michela Faggioni, Jaya Chandrasekhar, Deborah N Kalkman, Jason C Kovacic, Joseph Sweeny, Nitin Barman, Pedro Moreno, Pooja Vijay, Srushthi Shah, George Dangas, Annapoorna Kini, Samin Sharma, Roxana Mehran
BACKGROUND: High-intensity statins (HIS) are recommended for secondary prevention following percutaneous coronary intervention (PCI). We aimed to describe temporal trends and determinants of HIS prescriptions after PCI in a usual-care setting. METHODS: All patients with age ≤75 years undergoing PCI between January 2011 and May 2016 at an urban, tertiary care center and discharged with available statin dosage data were included. HIS were defined as atorvastatin 40 or 80 mg, rosuvastatin 20 or 40 mg, and simvastatin 80 mg...
September 12, 2018: American Heart Journal
Fabian R Reimold, Matthew R Reynolds
No abstract text is available yet for this article.
September 12, 2018: American Heart Journal
Leif Friberg
AIM: The aim of the study was to assess and compare the safety of antiarrhythmic drugs (AADs) in an unselected real-world population of patients with atrial fibrillation (AF). METHODS AND RESULTS: This is a study of all patients with diagnosed AF in the Swedish Patient register who filled a prescription for sotalol, amiodarone, dronedarone, flecainide or disopyramide during 2010 to 2015. The main end point consisted of arrhythmic death, successful resuscitation, new diagnosis of sustained ventricular tachycardia, ventricular fibrillation or implantation of ICD...
November 2018: American Heart Journal
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