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Acta Psychiatrica Scandinavica

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https://www.readbyqxmd.com/read/27886370/epigenetic-alterations-of-the-bdnf-gene-in-combat-related-post-traumatic-stress-disorder
#1
T Y Kim, S J Kim, H G Chung, J H Choi, S H Kim, J I Kang
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) plays a crucial role in modulating resilience and vulnerability to stress. The aim of this study was to investigate whether epigenetic regulation of the BDNF gene is a biomarker of post-traumatic stress disorder (PTSD) development among veterans exposed to combat in the Vietnam War. METHODS: Using the Clinician-Administered PTSD Scale, combat veterans were grouped into those with (n = 126) and without (n = 122) PTSD...
November 25, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27878807/manic-switches-induced-by-antidepressants-an-umbrella-review-comparing-randomized-controlled-trials-and-observational-studies
#2
N Allain, C Leven, B Falissard, J-S Allain, J-M Batail, E Polard, F Montastruc, D Drapier, F Naudet
OBJECTIVE: We aimed to explore whether the prevalence of manic switch was underestimated in randomized controlled trials (RCTs) compared to observational studies (OSs). METHOD: Meta-analyses and simple and systematic reviews were identified by two reviewers in a blinded, standardized manner. All relevant references were extracted to include RCTs and OSs that provided data about manic switch prevalence after antidepressant treatment for a major depressive episode...
November 23, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27870529/infections-and-exposure-to-anti-infective-agents-and-the-risk-of-severe-mental-disorders-a-nationwide-study
#3
O Köhler, L Petersen, O Mors, P B Mortensen, R H Yolken, C Gasse, M E Benros
OBJECTIVE: Severe infections are associated with increased risks of mental disorders; however, this is the first large-scale study investigating whether infections treated with anti-infective agents in the primary care setting increase the risks of schizophrenia and affective disorders. METHOD: We identified all individuals born in Denmark 1985-2002 (N = 1 015 447) and studied the association between infections treated with anti-infective agents and the subsequent risk of schizophrenia and affective disorders during 1995-2013...
November 21, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27864830/risk-of-psychiatric-disorders-self-harm-behaviour-and-service-use-associated-with-bariatric-surgery
#4
Z Kovacs, J B Valentin, R E Nielsen
OBJECTIVE: To investigate psychiatric outcomes after bariatric surgery, including suicide, self-harm, psychiatric service use and substance misuse. METHOD: Retrospective study on a Danish nationwide register-based cohort of 22 451 patients followed for 1 029 736 person-years. Data were analysed utilizing single- and multi-event Cox regression with non-operated controls with obesity and mirror-image analyses with the operated patient serving as their own controls...
November 19, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27864826/dietary-intervention-in-the-dystopian-world-of-severe-mental-illness-measure-for-measure-then-manage
#5
LETTER
S B Teasdale, P B Ward, K Samaras
No abstract text is available yet for this article.
November 19, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27858966/changes-in-interleukin-6-levels-during-electroconvulsive-therapy-may-reflect-the-therapeutic-response-in-major-depression
#6
K Järventausta, A Sorri, O Kampman, M Björkqvist, K Tuohimaa, M Hämäläinen, E Moilanen, E Leinonen, J Peltola, K Lehtimäki
OBJECTIVE: Interleukin-6 (IL-6) has been reported to be elevated in major depressive disorder (MDD) but decreased by antidepressive medication. IL-6 levels are markedly elevated both after epileptic seizures and single electroconvulsive therapy (ECT) session, but long-term changes in IL-6 levels after ECT have not been studied. The correlation between immediate and long-term changes in proinflammatory cytokines and outcome after ECT was investigated. METHOD: Thirty patients suffering from MDD participated in the study...
November 14, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27858958/advanced-parental-age-and-autism-risk-in-children-a-systematic-review-and-meta-analysis
#7
S Wu, F Wu, Y Ding, J Hou, J Bi, Z Zhang
OBJECTIVE: Advanced parental age has raised additional concern as a risk factor of autism. We conducted a meta-analysis of observational studies investigating the association between advanced parental age and risk of autism. METHOD: PubMed, EMBASE, and Web of Science were searched for reports published up to November 11, 2015. Risk estimates from individual studies were pooled using random-effects models. RESULTS: Twenty-seven studies were included in the meta-analysis...
November 14, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27858962/a-randomized-trial-of-brief-dialectical-behaviour-therapy-skills-training-in-suicidal-patients-suffering-from-borderline-disorder
#8
Shelley F McMain, Tim Guimond, Ryan Barnhart, Liat Habinski, David L Streiner
OBJECTIVE: Evidence-based therapies for borderline personality disorder (BPD) are lengthy and scarce. Data on brief interventions are limited, and their role in the treatment of BPD is unclear. Our aim was therefore to evaluate the clinical effectiveness of brief dialectical behaviour therapy (DBT) skills training as an adjunctive intervention for high suicide risk in patients with BPD. METHOD: Eighty-four out-patients were randomized to 20 weeks of DBT skills (n = 42) or a waitlist (WL; n = 42)...
November 13, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27858964/evidence-for-clinical-progression-of-unipolar-and-bipolar-disorders
#9
REVIEW
L V Kessing, P K Andersen
OBJECTIVE: It is a widely held belief that affective disorders are progressive of nature; however, some recent reviews have questioned this belief. The objective of the present systematic literature review was to present evidence for associations between number of affective episodes and (i) the risk of recurrence of episodes, (ii) probability of recovery from episodes, (iii) severity of episodes, (iv) the threshold for developing episodes, and (v) progression of cognitive deficits in unipolar and bipolar disorders...
November 10, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27858959/progression-from-unipolar-depression-to-schizophrenia
#10
Katherine L Musliner, Trine Munk-Olsen, Ole Mors, Søren D Østergaard
OBJECTIVE: To examine progression from unipolar depression (UD) to schizophrenia and to identify groups of UD patients at elevated risk for progression. METHOD: Historical prospective cohort study using data from Danish national registers. The sample included 71 932 individuals who received a diagnosis of UD in Denmark between January 1, 1995, and May 31, 2013. Analyses were conducted using Kaplan-Meier estimates and Cox regressions. RESULTS: The 18...
November 4, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27805260/can-subsyndromal-manifestations-of-major-depression-be-identified-in-children-at-risk
#11
M Uchida, M Fitzgerald, K Lin, N Carrellas, H Woodworth, J Biederman
OBJECTIVE: Children of parents with major depression are at significantly increased risk for developing major depression themselves; however, not all children at genetic risk will develop major depressive disorder (MDD). We investigated the utility of subsyndromal scores on the Child Behavior Checklist (CBCL) Anxiety/Depression scale in identifying children at the highest risk for pediatric MDD from among the pool of children of parents with MDD or bipolar disorder. METHOD: The sample was derived from two previously conducted longitudinal case-control family studies of psychiatrically and pediatrically referred youth and their families...
November 2, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27800603/hippocampal-volume-and-the-course-of-depressive-symptoms-over-eight-years-of-follow-up
#12
J Buddeke, M Kooistra, N P A Zuithoff, L Gerritsen, G J Biessels, Y van der Graaf, M I Geerlings
OBJECTIVE: To estimate the association between hippocampal and total brain volume and the course of depressive symptoms over eight years of follow-up in patients with a history of vascular disease. METHOD: Within the SMART-Medea study, 636 participants (62 ± 10 years) had a 1.5-tesla brain MRI obtaining hippocampal and total brain volumes. Depressive symptoms were assessed with the Patient Health Questionnaire-9 biannually during eight-year follow-up. Generalized estimating equation models with robust standard errors were used to assess the associations of hippocampal and total brain volumes with depressive symptoms during follow-up adjusting for age, sex, education, and intracranial volume...
November 1, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27690210/a-systematic-review-of-trial-registration-and-selective-outcome-reporting-in-psychotherapy-randomized-controlled-trials
#13
H A Bradley, J J Rucklidge, R T Mulder
OBJECTIVE: Selective outcome reporting poses serious implications on our evidence base for best practice. The extent to which selective outcome reporting and trial registration occurs in the wider psychotherapy literature needs to be investigated. METHOD: Randomized controlled psychotherapy trials published between 2010 and 2014 were selected from the five highest impact factor journals in clinical psychology that publish clinical trials. Data on primary and secondary outcomes, funding, and participant numbers were extracted from the article and registry and compared...
September 30, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27624381/use-of-psychotropic-drugs-in-patients-with-autism-spectrum-disorders-a-systematic-review
#14
K Jobski, J Höfer, F Hoffmann, C Bachmann
OBJECTIVE: The objective of this review was to examine prevalence and patterns of psychopharmacotherapy in individuals with autism spectrum disorder (ASD). METHOD: A systematic literature search in PubMed, CINAHL, and PsycINFO was performed, including articles published up to November 18, 2015. RESULTS: A total of 47 studies (data collection: 1976-2012), encompassing >300 000 individuals with ASD, were included. The prevalence of psychopharmacotherapy ranged from 2...
September 13, 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27869992/electroconvulsive-therapy-and-cognition-a-salutary-reappraisal
#15
EDITORIAL
C H Kellner, K G Farber
No abstract text is available yet for this article.
December 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27869991/reactive-aggression-in-young-patients-with-adhd-a-critical-role-for-small-provocations
#16
LETTER
G P Borgs, K Runions, C S Biskup, W Königschulte, P Rao, J Wong, J Moore, R M Stewart, F D Zepf
No abstract text is available yet for this article.
December 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27869990/association-of-positive-and-negative-syndrome-scale-short-forms-with-global-functioning-and-quality-of-life
#17
LETTER
L Hochstrasser, S Borgwardt, M Lambert, B G Schimmelmann, U E Lang, R-D Stieglitz, C G Huber
No abstract text is available yet for this article.
December 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27869989/association-of-positive-and-negative-syndrome-scale-panss-short-forms-with-global-functioning-and-quality-of-life
#18
LETTER
S D Østergaard, O Mors, C U Correll, P Bech
No abstract text is available yet for this article.
December 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27869988/corrigendum
#19
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27744649/incidence-characteristics-and-course-of-narrow-phenotype-paediatric-bipolar-i-disorder-in-the-british-isles
#20
A Sharma, J Neely, N Camilleri, A James, H Grunze, A Le Couteur
OBJECTIVE: To estimate the surveillance incidence of first-time diagnosis of narrow phenotype bipolar I disorder (NPBDI) in young people under 16 years by consultants in child and adolescent psychiatry (CCAP) in the British Isles and describe symptoms, comorbidity, associated factors, management strategies and clinical outcomes at 1-year follow-up. METHOD: Active prospective surveillance epidemiology was utilised to ask 730 CCAP to report cases of NPBDI using the child and adolescent psychiatry surveillance system...
December 2016: Acta Psychiatrica Scandinavica
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