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Acta Psychiatrica Scandinavica

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https://www.readbyqxmd.com/read/28332705/global-brain-asymmetry-is-increased-in-schizophrenia-and-related-to-avolition
#1
C Núñez, N Paipa, C Senior, M Coromina, S Siddi, S Ochoa, G Brébion, C Stephan-Otto
OBJECTIVE: Schizophrenia may be the result of a failure of the normal lateralization process of the brain. However, whole-brain asymmetry has not been assessed up to date. Here, we propose a novel measure of global brain asymmetry based on the Dice coefficient to quantify similarity between brain hemispheres. METHOD: Global gray and white matter asymmetry was calculated from high-resolution T1 structural images acquired from 24 patients with schizophrenia and 26 healthy controls, age- and sex-matched...
March 23, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28332704/risk-of-discontinuation-of-antipsychotic-long-acting-injections-vs-oral-antipsychotics-in-real-life-prescribing-practice-a-community-based-study
#2
H Verdoux, E Pambrun, M Tournier, J Bezin, A Pariente
OBJECTIVE: To compare the risk of discontinuation of ambulatory antipsychotic treatment in persons treated with antipsychotic long-acting injections (LAIs) or by oral antipsychotics (OAPs). METHODS: The study was performed in a representative sample of persons newly treated with OAPs (n = 6904) affiliated to the French Insurance Healthcare system. The risk of all-cause discontinuation was compared in patients prescribed OAPs (n = 246) vs. matched patients prescribed LAIs (n = 246) using multivariate survival analyses...
March 23, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28332236/the-mortality-rate-of-electroconvulsive-therapy-a-systematic-review-and-pooled-analysis
#3
REVIEW
N Tørring, S N Sanghani, G Petrides, C H Kellner, S D Østergaard
OBJECTIVE: Electroconvulsive therapy (ECT) remains underutilized because of fears of cognitive and medical risks, including the risk of death. In this study, we aimed to assess the mortality rate of ECT by means of a systematic review and pooled analysis. METHOD: The study was conducted in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline. The ECT-related mortality rate was calculated as the total number of ECT-related deaths reported in the included studies divided by the total number of ECT treatments...
March 23, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28332188/mitochondrial-dysfunction-a-link-between-antibiotic-use-and-increased-risk-of-severe-mental-disorders
#4
LETTER
William T Regenold
No abstract text is available yet for this article.
March 23, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28316080/toward-a-very-brief-self-report-to-assess-the-core-symptoms-of-depression-vqids-sr5
#5
N De La Garza, A John Rush, B D Grannemann, M H Trivedi
OBJECTIVE: To develop a short, 5-item measure of the core symptoms of depression based on the 16-item Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR16 ) and to evaluate psychometric properties of this new measure (Very Quick Inventory of Depressive Symptomatology - Self-Report: VQIDS-SR5 ). METHOD: Using data from a convenience sample of the Combining Medications to Enhance Depression Outcomes (CO-MED) trial, we evaluated the psychometric properties of the VQIDS-SR5 , its sensitivity to change, and its comparability to the QIDS-SR16 and clinician-rated scales (QIDS-C16 and VQIDS-C5 )...
March 17, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28281293/hypomania-checklist-32-cross-validation-of-shorter-versions-screening-for-bipolar-disorders-in-an-epidemiological-study
#6
T D Meyer, E Castelao, M Gholamrezaee, J Angst, M Preisig
OBJECTIVE: Self-reports such as Hypomania Checklist (HCL-32) can be used to enhance recognition of bipolar disorders, but they are often too long and only validated in clinical samples. The objectives of this study are therefore to test whether (i) the HCL-32 can be used for screening in the community and (ii) whether two previously suggested shorter versions would do as well. METHOD: Data stemmed from the CoLaus|PsyColaus, a prospective cohort study which included randomly selected residents aged 35-66 years from an urban area...
March 9, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28276052/perception-of-emotional-prosody-in-adults-with-attention-deficit-hyperactivity-disorder
#7
B Kis, N Guberina, M Kraemer, F Niklewski, I Dziobek, J Wiltfang, M Abdel-Hamid
OBJECTIVE: Attention deficit hyperactivity disorder (ADHD) is associated with social conflicts. The purpose of this study was to explore domains of social cognition in adult patients with ADHD. METHODS: The assessment of social cognition was based on established neuropsychological tests: the Tübinger Affect Battery (TAB) for prosody and the Cambridge Behaviour Scale (CBS) for empathy. The performance of adults with ADHD (N = 28) was compared with the performance of a control group (N = 29) matched according to basic demographic variables...
March 9, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28260264/clinical-high-risk-for-psychosis-the-association-between-momentary-stress-affective-and-psychotic-symptoms
#8
Y van der Steen, J Gimpel-Drees, T Lataster, W Viechtbauer, C J P Simons, M Lardinois, T Michel, B Janssen, A Bechdolf, M Wagner, I Myin-Germeys
OBJECTIVE: The aim of this study was to assess associations between momentary stress and both affective and psychotic symptoms in everyday life of individuals at clinical high risk (CHR), compared to chronic psychotic patients and healthy controls, in search for evidence of early stress sensitization. It also assessed whether psychotic experiences were experienced as stressful. METHOD: The experience sampling method was used to measure affective and psychotic reactivity to everyday stressful activities, events and social situations in 22 CHR patients, 24 patients with a psychotic disorder and 26 healthy controls...
March 5, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28260235/no-cognitive-enhancing-effect-of-glp-1-receptor-agonism-in-antipsychotic-treated-obese-patients-with-schizophrenia
#9
P L Ishøy, B Fagerlund, B V Broberg, N Bak, F K Knop, B Y Glenthøj, B H Ebdrup
OBJECTIVE: Schizophrenia is associated with profound cognitive and psychosocial impairments. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are used for diabetes and obesity treatment, and animal studies have indicated cognitive-enhancing effects. In this investigator-initiated, double-blind, randomized, placebo-controlled trial, we tested non-metabolic effects of exenatide once-weekly (Bydureon™) in obese, antipsychotic-treated patients with schizohrenia spectrum disorder. METHOD: Before and after 3 months of exenatide (N = 20) or placebo (N = 20) treatment, patients were assessed with the following: Brief Assessment of Cognition in Schizophrenia (BACS), Rey-Osterreith complex figure test (REY), Short-Form Health Survey (SF-36), Personal and Social Performance Scale (PSP) and the Positive and Negative Syndrome Scale (PANSS)...
March 5, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28260234/affect-lability-predicts-occurrence-of-suicidal-ideation-in-bipolar-patients-a-two-year-prospective-study
#10
D Ducasse, I Jaussent, S Guillaume, J M Azorin, F Bellivier, R Belzeaux, T Bougerol, B Etain, S Gard, C Henry, J P Kahn, M Leboyer, J Loftus, C Passerieux, E Olié, P Courtet
OBJECTIVE: The aim of our study was to investigate, in bipolar patients, whether affect lability was associated with suicidal ideation incidence during 2-year follow-up, and which subtype of affect lability was associated with suicidal ideation. METHOD: A total of 319 euthymic or mildly depressed bipolar outpatients recruited in the French FondaMental Advanced Centres of Expertise for Bipolar Disorder were divided into two subgroups according to the occurrence of suicidal ideation during a 2-year follow-up...
March 5, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28260229/is-there-consensus-across-international-evidence-based-guidelines-for-the-management-of-bipolar-disorder
#11
REVIEW
G B Parker, R K Graham, G Tavella
OBJECTIVE: To examine the level of agreement across professionally auspiced evidence-based guidelines for managing the bipolar disorders. METHODS: A literature search in PubMed, the National Guideline Clearinghouse, the Cochrane Database of Systematic Reviews and PsycInfo was undertaken using the search terms 'bipolar disorder' and 'guidelines', generating 11 evidence-based guidelines published by professional organisations over the 2002-2015 period. Each guideline was reviewed by two independent reviewers and key themes extracted via qualitative analyses...
March 5, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28256707/dopaminergic-agents-in-the-treatment-of-bipolar-depression-a-systematic-review-and-meta-analysis
#12
A G Szmulewicz, F Angriman, C Samamé, A Ferraris, D Vigo, S A Strejilevich
OBJECTIVE: To systematically examine the effects of dopaminergic agents (modafinil, armodafinil, pramipexole, methylphenidate, and amphetamines) on bipolar depression outcomes. METHODS: Meta-analysis of randomized controlled trials was performed to assess the efficacy and safety of treatment with dopaminergic agents in bipolar depression. In a secondary analysis, findings from both randomized controlled trials and high-quality observational studies were pooled by means of meta-analytic procedures to explore dopaminergic treatment-related new mania...
March 3, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28240781/does-psychotherapy-work-an-umbrella-review-of-meta-analyses-of-randomized-controlled-trials
#13
E Dragioti, V Karathanos, B Gerdle, E Evangelou
OBJECTIVE: To map and evaluate the evidence across meta-analyses of randomized controlled trials (RCTs) of psychotherapies for various outcomes. METHODS: We identified 173 eligible studies, including 247 meta-analyses that synthesized data from 5157 RCTs via a systematic search from inception to December 2016 in the PubMed, PsycINFO and Cochrane Database of Systematic Reviews. We calculated summary effects using random-effects models, and we assessed between-study heterogeneity...
February 27, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28211584/csf-ykl-40-and-gap-43-are-related-to-suicidal-ideation-in-older-women
#14
I Rymo, S Kern, M Bjerke, H Zetterberg, T Marlow, K Blennow, P Gudmundsson, I Skoog, M Waern
OBJECTIVE: To investigate possible relationships between suicidal ideation and cerebrospinal fluid (CSF) levels of glial markers YKL-40 (also known as chitinase-3-like protein 1), growth-associated protein-43 (GAP-43) and myelin basic protein (MBP). METHOD: The sample was obtained from the Prospective Population Study of Women and included 86 women without dementia who underwent both psychiatric examinations and lumbar puncture (LP). Eight of these women reported past-month suicidal ideation...
February 17, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28190269/a-systematic-review-of-visual-processing-and-associated-treatments-in-body-dysmorphic-disorder
#15
REVIEW
F Beilharz, D J Castle, S Grace, S L Rossell
OBJECTIVE: Recent advances in body dysmorphic disorder (BDD) have explored abnormal visual processing, yet it is unclear how this relates to treatment. The aim of this study was to summarize our current understanding of visual processing in BDD and review associated treatments. METHOD: The literature was collected through PsycInfo and PubMed. Visual processing articles were included if written in English after 1970, had a specific BDD group compared to healthy controls and were not case studies...
February 12, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28190254/anticonvulsants-and-suicide-attempts-in-bipolar-i-disorders
#16
F Bellivier, R Belzeaux, J Scott, P Courtet, J-L Golmard, J-M Azorin
OBJECTIVE: To identify risk factors for suicide attempts (SA) in individuals commencing treatment for a manic or mixed episode. METHOD: A total of 3390 manic or mixed cases with bipolar disorder (BD) type I recruited from 14 European countries were included in a prospective, 2-year observational study. Poisson regression models were used to identify individual and treatment factors associated with new SA events. Two multivariate models were built, stratified for the presence or absence of prior SA...
February 12, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28188631/emotion-processing-and-psychosocial-functioning-in-euthymic-bipolar-disorder
#17
A Aparicio, J L Santos, E Jiménez-López, A Bagney, R Rodríguez-Jiménez, E M Sánchez-Morla
OBJECTIVE: To examine emotion processing in euthymic bipolar patients (EBP) compared to healthy controls. In addition, to determine whether or not there is an association between emotion processing and psychosocial functioning. MATERIAL AND METHODS: A sample of 60 EBP and 60 healthy controls matched for age, gender, education level, and premorbid intelligence were studied. All subjects were assessed using the MATRICS Consensus Cognitive Battery (MCCB) and two additional executive function measures: the Trail Making Test-Part B and the Stroop Test...
February 11, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28168698/cannabis-use-and-symptom-severity-in-individuals-at-ultra-high-risk-for-psychosis-a-meta-analysis
#18
R Carney, J Cotter, J Firth, T Bradshaw, A R Yung
OBJECTIVE: We aimed to assess whether individuals at ultra high risk (UHR) for psychosis have higher rates of cannabis use and cannabis use disorders (CUDs) than non-UHR individuals and determine whether UHR cannabis users have more severe psychotic experiences than non-users. METHOD: We conducted a meta-analysis of studies reporting cannabis use in the UHR group and/or positive or negative symptoms among UHR cannabis users and non-users. Logit event rates were calculated for cannabis use, in addition to odds ratios to assess the difference between UHR and controls...
February 7, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28160276/harm-avoidance-and-childhood-adversities-in-patients-with-obsessive-compulsive-disorder-and-their-unaffected-first-degree-relatives
#19
K Bey, L Lennertz, A Riesel, J Klawohn, C Kaufmann, S Heinzel, R Grützmann, N Kathmann, M Wagner
OBJECTIVE: The etiology of obsessive-compulsive disorder (OCD) is assumed to involve interactions between genetically determined vulnerability factors and significant environmental features. Here, we aim to investigate how the personality trait harm avoidance and the experience of childhood adversities contribute to OCD. METHOD: A total of 169 patients with OCD, 157 healthy comparison subjects, and 57 unaffected first-degree relatives of patients with OCD participated in the study...
February 3, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28155220/the-impact-of-clozapine-on-hospital-use-a-systematic-review-and-meta-analysis
#20
R Land, D Siskind, P McArdle, S Kisely, K Winckel, S A Hollingworth
OBJECTIVE: The objective of this study was to perform a systematic review and meta-analysis of studies reporting the impact of clozapine on hospital use in people with a psychotic illness. METHOD: PubMed, EMBASE, PsycINFO and the Cochrane Schizophrenia Group Trials Register were systematically searched from inception to 12 October 2016. We included all trials and observational studies, except case reports. RESULTS: Thirty-seven studies were included...
February 3, 2017: Acta Psychiatrica Scandinavica
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