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Acta Psychiatrica Scandinavica

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https://www.readbyqxmd.com/read/29766490/emotional-hyper-reactivity-and-cardiometabolic-risk-in-remitted-bipolar-patients-a-machine-learning-approach
#1
A A Dargél, F Roussel, S Volant, B Etain, R Grant, J-M Azorin, K M'Bailara, F Bellivier, T Bougerol, J-P Kahn, P Roux, V Aubin, P Courtet, M Leboyer, F Kapczinski, C Henry
OBJECTIVE: Remitted bipolar disorder (BD) patients frequently present with chronic mood instability and emotional hyper-reactivity, associated with poor psychosocial functioning and low-grade inflammation. We investigated emotional hyper-reactivity as a dimension for characterization of remitted BD patients, and clinical and biological factors for identifying those with and without emotional hyper-reactivity. METHOD: A total of 635 adult remitted BD patients, evaluated in the French Network of Bipolar Expert Centers from 2010-2015, were assessed for emotional reactivity using the Multidimensional Assessment of Thymic States...
May 15, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29761489/mortality-in-unipolar-depression-preceding-and-following-chronic-somatic-diseases-a-nationwide-danish-study
#2
A Koyanagi, O Köhler-Forsberg, M E Benros, T Munk Laursen, J M Haro, Merete Nordentoft, Carsten Hjorthøj
OBJECTIVE: It is largely unknown how depression prior to and following somatic diseases affects mortality. Thus, we examined how the temporal order of depression and somatic diseases affects mortality risk. METHOD: Data were from a Danish population-based cohort from 1995 to 2013, which included all residents in Denmark during the study period (N = 4 984 912). Nineteen severe chronic somatic disorders from the Charlson Comorbidity Index were assessed. The date of first diagnosis of depression and somatic diseases was identified...
May 14, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29756288/mixed-states-in-bipolar-and-major-depressive-disorders-systematic-review-and-quality-appraisal-of-guidelines
#3
REVIEW
N Verdolini, D Hidalgo-Mazzei, A Murru, I Pacchiarotti, L Samalin, A H Young, E Vieta, A F Carvalho
OBJECTIVE: This systematic review provided a critical synthesis and a comprehensive overview of guidelines on the treatment of mixed states. METHOD: The MEDLINE/PubMed and EMBASE databases were systematically searched from inception to March 21st, 2018. International guidelines covering the treatment of mixed episodes, manic/hypomanic, or depressive episodes with mixed features were considered for inclusion. A methodological quality assessment was conducted with the Appraisal of Guidelines for Research and Evaluation-AGREE II...
May 13, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29726004/factors-associated-with-poor-functional-outcome-in-bipolar-disorder-sociodemographic-clinical-and-neurocognitive-variables
#4
J Sanchez-Moreno, C M Bonnin, A González-Pinto, B L Amann, B Solé, V Balanzá-Martinez, C Arango, E Jiménez, R Tabarés-Seisdedos, M P Garcia-Portilla, A Ibáñez, J M Crespo, J L Ayuso-Mateos, A Martinez-Aran, C Torrent, E Vieta
OBJECTIVE: The current investigation aimed at studying the sociodemographic, clinical, and neuropsychological variables related to functional outcome in a sample of euthymic patients with bipolar disorder(BD) presenting moderate-severe levels of functional impairment. METHODS: Two-hundred and thirty-nine participants with BD disorders and with Functioning Assessment Short Test(FAST) scores equal or above 18 were administered a clinical and diagnostic interview, and the administration of mood measure scales and a comprehensive neuropsychological battery...
May 3, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29707778/electroconvulsive-therapy-increases-brain-volume-in-major-depression-a-systematic-review-and-meta-analysis
#5
REVIEW
K Gbyl, P Videbech
OBJECTIVE: The main purpose of this review was to synthesise evidence on ECT's effects on brain's structure. METHOD: A systematic literature review of longitudinal studies of depressed patients treated with ECT using magnetic resonance imaging (MRI) and meta-analysis of ECT's effect on hippocampal volume. RESULTS: Thirty-two studies with 467 patients and 285 controls were included. The MRI studies did not find any evidence of ECT-related brain damage...
April 29, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29682735/criminal-victimization-and-psychotic-experiences-cross-sectional-associations-in-35-low-and-middle-income-countries
#6
J E DeVylder, I Kelleher, H Oh, B G Link, L H Yang, A Koyanagi
OBJECTIVE: Criminal victimization has been associated with elevated risk for psychotic symptoms in the United Kingdom, but has not been studied in low- and middle-income countries (LMICs). Understanding whether crime exposure may play a role in the social etiology of psychosis could help guide prevention and intervention efforts. METHOD: We tested the hypothesis that criminal victimization would be associated with elevated odds of psychotic experiences in 35 LMICs (N = 146 999) using cross-sectional data from the World Health Organization World Health Survey...
April 22, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29682732/a-morphometric-signature-of-depressive-symptoms-in-unmedicated-patients-with-mood-disorders
#7
T Wise, L Marwood, A M Perkins, A Herane-Vives, S C R Williams, A H Young, A J Cleare, D Arnone
OBJECTIVE: A growing literature indicates that unipolar depression and bipolar depression are associated with alterations in grey matter volume. However, it is unclear to what degree these patterns of morphometric change reflect symptom dimensions. Here, we aimed to predict depressive symptoms and hypomanic symptoms based on patterns of grey matter volume using machine learning. METHOD: We used machine learning methods combined with voxel-based morphometry to predict depressive and self-reported hypomanic symptoms from grey matter volume in a sample of 47 individuals with unmedicated unipolar and bipolar depression...
April 22, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29675994/psychotic-like-experiences-in-pre-adolescence-what-precedes-the-antecedent-symptoms-of-severe-mental-illness
#8
K Bolhuis, M E Koopman-Verhoeff, L M E Blanken, D Cibrev, V W V Jaddoe, F C Verhulst, M H J Hillegers, S A Kushner, H Tiemeier
OBJECTIVE: Adolescent psychotic-like experiences predict the onset of psychosis, but also predict subsequent non-psychotic disorders. Therefore, it is crucial to better understand the aetiology of psychotic-like experiences. This study examined whether (a) child emotional and behavioural problems at 3 and 6 years, or (b) childhood adversities were associated with psychotic-like experiences at age 10 years. METHOD: This prospective study was embedded in the Generation R Study; 3984 children (mean age 10 years) completed a psychotic-like experiences questionnaire...
April 19, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29667181/the-specific-social-costs-of-expressive-negative-symptoms-in-schizophrenia-reduced-smiling-predicts-interactional-outcome
#9
M Riehle, S Mehl, T M Lincoln
OBJECTIVE: We tested whether people with schizophrenia and prominent expressive negative symptoms (ENS) show reduced facial expressions in face-to-face social interactions and whether this expressive reduction explains negative social evaluations of these persons. METHOD: We compared participants with schizophrenia with high ENS (n = 18) with participants with schizophrenia with low ENS (n = 30) and with healthy controls (n = 39). Participants engaged in an affiliative role-play that was coded for the frequency of positive and negative facial expression and rated for social performance skills and willingness for future interactions with the respective role-play partner...
April 17, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29667167/out-of-home-placement-to-age-18-years-in-children-exposed-to-a-postpartum-mental-disorder
#10
Simone N Vigod, Thomas Munk Laursen, Anne Ranning, Merete Nordentoft, Trine Munk-Olsen
OBJECTIVES: Little is known about risk of custody loss or out-of-home placement among children whose mothers experience postpartum mental disorders, and whether this risk differs from that of children whose mothers had earlier onset of their mental disorder. METHODS: National Danish registers comprising 1 868 467 births (1982-2012) were used to determine how the timing of maternal illness onset influences out-of-home placement risk up to age 18 years among children exposed to a maternal mental disorder...
April 17, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29611870/initial-severity-of-major-depression-and-efficacy-of-new-generation-antidepressants-individual-participant-data-meta-analysis
#11
T A Furukawa, K Maruo, H Noma, S Tanaka, H Imai, K Shinohara, K Ikeda, S Yamawaki, S Z Levine, Y Goldberg, S Leucht, A Cipriani
OBJECTIVE: The role of baseline severity as effect modifier in various psychiatric disorders is a topic of controversy and of clinical import. This study aims to examine whether baseline severity modifies the efficacy of various antidepressants for major depression through individual participant data (IPD) meta-analysis. METHOD: We identified all placebo-controlled, double-blind randomised trials of new generation antidepressants in the acute phase treatment of major depression conducted in Japan and requested their IPD through the public-private partnerships (PPPs) between the relevant academic societies and the pharmaceutical companies...
April 3, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29603145/natural-cause-mortality-in-persons-with-serious-mental-illness
#12
F Dickerson, A Origoni, J Schroeder, M Adamos, E Katsafanas, S Khushalani, C L G Savage, L A B Schweinfurth, C Stallings, K Sweeney, R Yolken
OBJECTIVE: To identify the determinants of natural cause mortality in a cohort of individuals with serious mental illness assessed prospectively. METHOD: Persons with schizophrenia (n = 789) and bipolar disorder (n = 498), mean age of 38 (s.d. 12.6) years, underwent an in-person clinical assessment. They also had a blood sample drawn from which infectious disease markers were measured. Mortality was subsequently determined utilizing data from the National Death Index following a period of up to 16...
March 30, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29603140/differences-in-the-placebo-response-in-duloxetine-and-venlafaxine-trials
#13
J Breilmann, T A Furukawa, T Becker, M Koesters
OBJECTIVE: Our analysis aimed at comparing the placebo effect sizes from randomized controlled trials (RCTs) of two widely prescribed antidepressants, namely duloxetine and venlafaxine, and at analysing a potential influence of the investigated drugs on the placebo response. METHOD: We conducted a comprehensive systematic review and meta-analysis of placebo-controlled, double-blind RCTs, which examined the efficacy of duloxetine and venlafaxine in the acute treatment of major depressive disorder...
March 30, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29602172/no-differences-in-olanzapine-and-risperidone-related-weight-gain-between-women-and-men-a-meta-analysis-of-short-and-middle-term-treatment
#14
G Schoretsanitis, M Drukker, J Van Os, K R J Schruers, M Bak
OBJECTIVE: A plethora of data deriving from single studies as well as meta-analyses demonstrates that weight gain is associated with the exposure to the majority of antipsychotics (AP). However, potential sex differences have widely evaded the attention of AP treatment trials. It is hypothesised that female patients gain more weight compared with male patients due to their enhanced susceptibility to adverse drug reactions. METHOD: A meta-analysis was conducted using clinical trials of AP that reported weight change separately for female and male patients...
March 30, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29577236/recurrence-and-chronicity-of-major-depressive-disorder-and-their-risk-indicators-in-a-population-cohort
#15
M Ten Have, R de Graaf, S van Dorsselaer, M Tuithof, M Kleinjan, B W J H Penninx
OBJECTIVE: The naturalistic course of major depressive disorder (MDD) and risk indicators for recurrence and chronicity are best studied using a population sample without clear selection bias. However, such studies are scarce. This limits clinical decision-making concerning monitoring and maintenance treatment. METHOD: Data were used from the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among a representative adult population...
March 25, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29577229/comparison-of-guidelines-for-the-treatment-of-unipolar-depression-a-focus-on-pharmacotherapy-and-neurostimulation
#16
REVIEW
A J Bayes, G B Parker
OBJECTIVE: To determine the level of agreement across a set of evidence-based guidelines for management of the unipolar depressive disorders and with a focus on physical treatments. METHOD: A literature search was undertaken using the terms 'depression', 'depressive' and 'guidelines', using PubMed, Cochrane Database of Systematic Reviews and the National Guideline Clearinghouse. Twelve national psychiatric or professional guideline-producing organizations were identified from the period 2007-2017, with guidelines qualitatively reviewed by two assessors...
March 25, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29536533/association-of-intracortical-myelin-and-cognitive-function-in-bipolar-i-disorder
#17
M Sehmbi, C D Rowley, L Minuzzi, F Kapczinski, M Steiner, R B Sassi, N A Bock, B N Frey
OBJECTIVE: Although cognitive dysfunction persists through affective and euthymic states in bipolar disorder (BD), its neurobiological correlates remain undetermined. We explore whole-cortex intracortical myelin (ICM) and cognition in BD-I and controls. METHODS: T1 -weighted images (3T) optimized for ICM measurement were analyzed using a surface-based approach. MRI signal was sampled at cortical mid-depth. Cognitive performance was measured via standardized computerized battery and paper-and-pencil Trails B...
March 13, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29508379/heterogeneity-of-functional-outcomes-in-patients-with-bipolar-disorder-a-cluster-analytic-approach
#18
B Solé, C M Bonnin, E Jiménez, C Torrent, I Torres, C Varo, E Valls, L Montejo, C Gómez-Ocaña, Y Tomioka, E Vieta, A Martinez-Aran, M Reinares
OBJECTIVE: The aim was to examine the heterogeneity of psychosocial outcomes in euthymic bipolar disorder (BD) patients and analyse the potential influence of distinct variables on functioning. METHOD: Using a hierarchical cluster exploratory analysis, 143 euthymic patients with diagnosis of BD were grouped according to their functional performance based on domains scores of the Functioning Assessment Short Test (FAST). The resulting groups were compared on sociodemographic, clinical and neurocognitive variables to find factors associated with each functional cluster...
March 5, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29479669/exposure-to-selective-serotonin-reuptake-inhibitors-in-utero-and-early-elementary-school-outcomes
#19
K Kragholm, M P Andersen, R N Mortensen, L F Bech, C Polcwiartek, C Rohde, C Torp-Pedersen, P Videbech, J Nielsen
OBJECTIVE: Data on special education in offspring exposed to selective serotonin reuptake inhibitors (SSRIs) in utero are lacking. We examined associations of in utero SSRI exposure with special education needs and delayed elementary school start. METHODS: A population-based case-cohort study using Danish nationwide birth and prescription registry data from 2005 to 2008. Follow-up ends during 2011-2015 to capture special education needs during and delayed entry to the first elementary school year...
February 25, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29637548/repeated-sleep-deprivation-for-a-more-rapid-decrease-in-depressive-symptoms-in-combined-chronotherapy
#20
LETTER
S J M Druiven, Y Meesters, H Riese, R A Schoevers
No abstract text is available yet for this article.
May 2018: Acta Psychiatrica Scandinavica
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