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Acta Psychiatrica Scandinavica

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https://www.readbyqxmd.com/read/28922451/low-medical-morbidity-and-mortality-after-acute-courses-of-electroconvulsive-therapy-in-a-population-based-sample
#1
D M Blumberger, D P Seitz, N Herrmann, J G Kirkham, R Ng, C Reimer, P Kurdyak, A Gruneir, M J Rapoport, Z J Daskalakis, B H Mulsant, S N Vigod
BACKGROUND: To determine event rates for specific medical events and mortality among individuals receiving electroconvulsive therapy (ECT). METHOD: Population-based cohort study using health administrative data of acute ECT treatments delivered in Ontario, Canada, from 2003 to 2011. We measured the following medical event rates, per 10 000 ECT treatments, up to 7 and 30 days post-treatment: stroke, seizure, acute myocardial infarction, arrhythmia, pneumonia, pulmonary embolus, deep vein thrombosis, gastrointestinal bleeding, falls, hip fracture, and mortality...
September 18, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28891192/light-therapy-is-it-safe-for-the-eyes
#2
REVIEW
A Brouwer, H-T Nguyen, F J Snoek, D H van Raalte, A T F Beekman, A C Moll, M A Bremmer
OBJECTIVE: Light therapy has become an increasingly popular treatment for depression and a range of other neuropsychiatric conditions. Yet, concerns have been raised about the ocular safety of light therapy. METHOD: We conducted the first systematic review into the ocular safety of light therapy. A PubMed search on January 4, 2017, identified 6708 articles, of which 161 were full-text reviewed. In total, 43 articles reporting on ocular complaints and ocular examinations were included in the analyses...
September 10, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28871593/comment-on-vitamin-d-serum-levels-are-cross-sectionally-but-not-prospectively-associated-with-late-life-depression
#3
LETTER
T C Griffen
No abstract text is available yet for this article.
September 4, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28865406/resting-state-perfusion-in-the-language-network-is-linked-to-formal-thought-disorder-and-poor-functional-outcome-in-schizophrenia
#4
K Stegmayer, M Stettler, W Strik, A Federspiel, R Wiest, S Bohlhalter, S Walther
OBJECTIVE: Formal thought disorder (FTD) is a core symptom in schizophrenia. Here, we focus on resting state cerebral blood flow (rCBF) linked to dimensions of FTD. METHODS: We included 47 schizophrenia spectrum patients and 30 age- and gender-matched healthy controls. We assessed FTD with the assessment of thought, language, and communication (TLC) and imaging on a 3T MRI scanner. Within patients, we tested the association of FTD dimensions and in a subgroup (n = 27) the association of functional outcome after 6 months with whole brain rCBF...
September 2, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28865405/the-role-of-stress-regulation-genes-in-moderating-the-association-of-stress-and-daily-life-psychotic-experiences
#5
P Cristóbal-Narváez, T Sheinbaum, I Myin-Germeys, T R Kwapil, M de Castro-Catala, T Domínguez-Martínez, A Racioppi, M Monsonet, L Hinojosa-Marqués, R van Winkel, A Rosa, N Barrantes-Vidal
OBJECTIVE: The interaction of single nucleotide polymorphisms with both distal and proximal environmental factors across the extended psychosis phenotype is understudied. This study examined (i) the interaction of relevant SNPs with both early-life adversity and proximal (momentary) stress on psychotic experiences (PEs) in an extended psychosis sample; and (ii) differences between early-psychosis and non-clinical groups for these interactions. METHODS: Two hundred and forty-two non-clinical and 96 early-psychosis participants were prompted randomly eight times daily for 1 week to complete assessments of current experiences, including PEs and stress...
September 2, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28865404/from-depression-to-anxiety-and-back
#6
EDITORIAL
Eric Bui, Maurizio Fava
No abstract text is available yet for this article.
September 2, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28865402/effects-of-age-and-gender-on-the-serum-levels-of-clozapine-olanzapine-risperidone-and-quetiapine
#7
I Castberg, A A Westin, E Skogvoll, O Spigset
OBJECTIVE: To investigate serum concentrations of second-generation antipsychotics in relation to age and gender in a population ranging from 18 to 100 years. METHOD: Results from a routine therapeutic drug monitoring database were retrieved, and 43 079 samples from 11 968 patients were included (17 249 samples for clozapine, 16 171 samples for olanzapine, 5343 samples for risperidone, and 4316 samples for quetiapine). The dose-adjusted concentration was used as the primary target variable...
September 2, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28861900/does-persisting-fear-sustain-catatonia
#8
M Fink, E Shorter
OBJECTIVE: To examine the psychological substrate of catatonia. METHOD: Reviewing the historical descriptions and explanations of catatonic behaviours by clinicians from its delineation in the 19th century to the present. RESULTS: Patients with catatonia are often haunted by fears and terrors; this has not been widely appreciated, and certainly was lost from view in the days when catatonia was considered a subtype of schizophrenia. The report contributes to resolving a major question in catatonia: is the mind in stupor inactive, as the blank state that we picture in anesthetized patients, or is the mind active, so preoccupied as to exclude all other influences...
August 31, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28861892/sociodemographic-clinical-and-functional-long-term-outcomes-in-adolescents-and-young-adults-with-mental-disorders
#9
E Asselmann, H-U Wittchen, R Lieb, K Beesdo-Baum
OBJECTIVE: To examine unfavorable sociodemographic, clinical, and functional long-term outcomes for a range of adolescent mental disorders. METHODS: A total number of 2210 adolescents and young adults (14-24 years at baseline, T0) from a representative community sample were prospectively followed up (T1-T3) over 10 years. DSM-IV mental disorders, sociodemographic, clinical, and functional outcomes were assessed using the DIA-X/M-CIDI and its embedded assessment modules...
August 31, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28859218/incidence-of-early-anxiety-aggravation-in-trials-of-selective-serotonin-reuptake-inhibitors-in-depression
#10
J Näslund, F Hieronymus, J F Emilsson, A Lisinski, S Nilsson, E Eriksson
OBJECTIVE: Selective serotonin reuptake inhibitors (SSRIs) may aggravate anxiety and agitation during the first days of treatment but the frequency of such reactions remains unknown. METHOD: We analysed patient-level data from placebo-controlled trials of sertraline, paroxetine or citalopram in depressed adults. Somatic anxiety, psychic anxiety and psychomotor agitation as assessed using the Hamilton Depression Rating Scale (HDRS) were analysed in all trials (n = 8262); anxiety-related adverse events were analysed in trials investigating paroxetine and citalopram (n = 5712)...
August 31, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28851055/the-effect-of-adjunctive-telmisartan-treatment-on-psychopathology-and-cognition-in-patients-with-schizophrenia
#11
X Fan, X Song, M Zhao, L F Jarskog, R Natarajan, N Shukair, O Freudenreich, D C Henderson, D C Goff
OBJECTIVE: This study examined the effect of adjunctive telmisartan on psychopathology and cognition in olanzapine- or clozapine-treated patients with schizophrenia. METHOD: In a 12-week randomized, double-blind, placebo-controlled study, patients diagnosed with schizophrenia or schizoaffective disorder received either telmisartan (80 mg once per day) or placebo. Psychopathology was assessed using the Positive and Negative Syndrome Scale (PANSS) and the Scale for Assessment of Negative Symptoms (SANS), and a neuropsychological battery was used to assess cognitive performance...
August 29, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28846820/-no-cognitive-enhancing-effect-of-glp-1-receptor-agonism-in-antipsychotic-treated-obese-patients-with-schizophrenia-authors-response
#12
LETTER
B H Ebdrup, P L Ishøy, B Fagerlund, B V Broberg, N Bak, F K Knop, B Y Glenthøj
No abstract text is available yet for this article.
August 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28846815/reply
#13
LETTER
Rebecca Schneibel, Gregor Wilbertz, Christine Scholz, Manuel Becker, Tom Bschor, Dirk Schmoll
No abstract text is available yet for this article.
August 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28846801/increased-illness-burden-in-women-with-comorbid-bipolar-and-premenstrual-dysphoric-disorder-data-from-1-099-women-from-step-bd-study
#14
A Slyepchenko, B N Frey, B Lafer, A A Nierenberg, G S Sachs, R S Dias
BACKGROUND: The impact of comorbid premenstrual dysphoric disorder (PMDD) in women with bipolar disorder (BD) is largely unknown. AIMS: We compared illness characteristics and female-specific mental health problems between women with BD with and without PMDD. MATERIALS & METHODS: A total of 1 099 women with BD who participated in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) were studied. Psychiatric diagnoses and illness characteristics were assessed using the Mini International Neuropsychiatric Interview...
August 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28846800/trajectories-of-posttraumatic-growth-among-us-military-veterans-a-4-year-nationally-representative-prospective-cohort-study
#15
J Tsai, R H Pietrzak
OBJECTIVE: This study examined the nature and determinants of predominant trajectories of posttraumatic growth (PTG) over time. METHOD: Using data from a prospective, nationally representative survey of 2718 US veterans assessed in 2011, 2013, and 2015, we used latent growth mixture modeling to identify PTG trajectories, and to examine key determinants of PTG trajectories from a comprehensive set of sociodemographic, military, health, and psychosocial variables...
August 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28845530/association-between-the-antioxidant-uric-acid-and-depression-and-antidepressant-medication-use-in-96-989-individuals
#16
M K Wium-Andersen, C J Kobylecki, S Afzal, B G Nordestgaard
OBJECTIVE: In the last decade, several studies have suggested that depression is accompanied by increased oxidative stress and decreased antioxidant defenses. We tested the hypothesis that high levels of the antioxidant uric acid are associated with lower risk of hospitalization with depression and use of prescription antidepressant medication. METHOD: We examined plasma levels of the antioxidant uric acid in 96 989 individuals from two independent cohort studies...
August 28, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28832904/infectious-and-immunogenetic-factors-in-bipolar-disorder
#17
REVIEW
J Oliveira, A J Oliveira-Maia, R Tamouza, A S Brown, M Leboyer
OBJECTIVE: Despite the evidence supporting the association between infection and bipolar disorder (BD), the genetic vulnerability that mediates its effects has yet to be clarified. A genetic origin for the immune imbalance observed in BD, possibly involved in the mechanisms of pathogen escape, has, however, been suggested in recent studies. METHOD: Here, we present a critical review based on a systematic literature search of articles published until December 2016 on the association between BD and infectious/immunogenetic factors...
August 20, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28815548/persistent-increase-in-tnf-and-il-1-markers-in-severe-mental-disorders-suggests-trait-related-inflammation-a-one-year-follow-up-study
#18
R H Mørch, I Dieset, A Faerden, S Hope, M Aas, M Nerhus, E S Gardsjord, M Haram, R S Falk, I Joa, G Morken, I Agartz, P Aukrust, S Djurovic, I Melle, T Ueland, O A Andreassen
OBJECTIVE: We evaluated if plasma levels of inflammatory markers are persistently altered in severe mental disorders with psychotic symptoms or associated with state characteristics in a longitudinal study. METHODS: Soluble tumor necrosis factor receptor 1 (sTNF-R1), interleukin-1 receptor antagonist (IL-1Ra), von Willebrand factor (VWF), and osteoprotegerin (OPG) were measured in schizophrenia (n = 69) and affective (n = 55) spectrum patients at baseline and at one-year follow-up, and compared to healthy controls (HC) (n = 92) with analysis of covariance...
August 16, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28795405/genomewide-dna-methylation-analysis-in-combat-veterans-reveals-a-novel-locus-for-ptsd
#19
D Mehta, D Bruenig, T Carrillo-Roa, B Lawford, W Harvey, C P Morris, A K Smith, E B Binder, R McD Young, J Voisey
OBJECTIVE: Epigenetic modifications such as DNA methylation may play a key role in the aetiology and serve as biomarkers for post-traumatic stress disorder (PTSD). We performed a genomewide analysis to identify genes whose DNA methylation levels are associated with PTSD. METHOD: A total of 211 individuals comprising Australian male Vietnam War veterans (n = 96) and males from a general population belonging to the Grady Trauma Project (n = 115) were included. Genomewide DNA methylation was performed from peripheral blood using the Illumina arrays...
August 9, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28787526/factors-in-evaluating-in-patient-group-psychotherapy
#20
LETTER
A Sapunov, D Hubbeling, R Bertram
No abstract text is available yet for this article.
August 8, 2017: Acta Psychiatrica Scandinavica
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