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Acta Oto-laryngologica

Issam Saliba, Marc-Henri Asmar
BACKGROUND: Endolymphatic sac decompression has shown limited success for the treatment of Ménière's disease (MD). We have published a novel technique with very promising results for the treatment of refractory MD: the Endolymphatic Duct Blockage (EDB) with two titanium clips. One of the challenges of this technique was an increased incidence of intraoperative Cerebrospinal Fluid (CSF) Leak. OBJECTIVE: To assess the effect of intraoperative CSF Leak on short-term surgical outcomes...
July 17, 2018: Acta Oto-laryngologica
Eunsang Lee, Seung Jae Lee, Hyo Jun Kim, Jae Min Shin, Ji Ho Choi, Jae Yong Lee
BACKGROUND: Re-deviation of the nasal septum may occur after septoplasty. Because the cartilaginous septum grows until the age of 16-17 years, septoplasty is usually recommended thereafter. However, severely deviated septum may necessitate septoplasty in younger adolescents. OBJECTIVES: To compare the incidence of re-deviated nasal septum in patients who underwent septoplasty at ≤18 versus ≥19 years of age. MATERIALS AND METHODS: The medical records and endoscopic photographs of patients who underwent septoplasty between 2005 and 2015 were retrospectively reviewed...
July 17, 2018: Acta Oto-laryngologica
Takashi Kono, Tsutomu Ueda, Masaya Takumida, Hiromi Furuie, Takao Hamamoto, Sachio Takeno, Katsuhiro Hirakawa
OBJECTIVE: To determine if a lower dose of dexamethasone can be used in combination with fosaprepitant and palonosetron for cisplatin-induced nausea and vomiting in head and neck cancer patients, we conducted a single-center, two-arm, cross-over comparison study. METHODS: Patients were randomly assigned to either standard dose dexamethasone group: intravenous 9.9 mg on day 1 and 6.6 mg on days 2-4 or low-dose dexamethasone group: intravenous 3.3 mg on days 1-4 for the first course and crossed over to the other treatment for the second course...
July 17, 2018: Acta Oto-laryngologica
Tae Su Kim, Hyun Woo Lim, Chan Joo Yang, Yong Han Kim, Woo Ri Choi, Yeh Ree Kim, Jun Woo Park, Byung Chul Kang, Hong Ju Park
BACKGROUND: The peak head velocity influences on the video head impulse test (vHIT) results, but it has been not known how much the difference is. AIMS: To evaluate the clinical evidence for the superiority of high-velocity compared to low-velocity vHIT. MATERIAL AND METHODS: vHIT was performed in 30 patients with vestibular neuritis using two peak head velocities (mean 80 vs. 240°/s). vHIT gains and parameters of corrective saccades (CSs) were compared...
July 17, 2018: Acta Oto-laryngologica
Alexander Leo Luryi, Juliana Lawrence, Dennis Bojrab, Michael LaRouere, Seilesh Babu, Robert Hong, John Zappia, Eric Sargent, Eleanor Chan, Ilka C Naumann, Christopher A Schutt
BACKGROUND: Meniere's disease (MD)-associated benign paroxysmal positional vertigo (BPPV) is complex and difficult to diagnose, and reports of its prevalence, pathologic features and outcomes are sparse and conflicting. OBJECTIVE: Report disease characteristics and outcomes associated with the presence of MD in patients with BPPV. MATERIALS/METHODS: A retrospective study of patients with BPPV between 2007 and 2017 at a single, high-volume institution...
July 17, 2018: Acta Oto-laryngologica
Markus Wirth, Steffi Pigorsch, Ulrich Strassen, Felix Johnson, Anja Pickhard, Magdalena Wirth
OBJECTIVE: In a proportion of patients with cervical lymph node metastasis no primary can be found even with modern imaging and careful clinical examination (cancer of unknown primary syndrome = CUP syndrome). The ideal diagnostic approach is still debated on. METHODS: The clinical data of 75 patients (median age: 61.8 years; 16 females and 59 males), which have been treated for cervical squamous cell carcinoma of unknown primary syndrome in our hospital were retrospectively analyzed...
July 17, 2018: Acta Oto-laryngologica
Katri Aro, Leif Bäck, Antti Mäkitie, Laura Tapiovaara
BACKGROUND: Various detection methods to identify the primary in head and neck cancer of unknown primary (HN-CUP) require evaluation to improve and standardize management. OBJECTIVES: To evaluate the use of different diagnostic methods, which aim at decreasing the incidence of HN-CUP. MATERIAL AND METHODS: We conducted a retrospective analysis of patients with HN-CUP at the Helsinki University Hospital during 1995-2011. We evaluated clinical assessment, definitive treatment, histopathology, and follow up...
July 17, 2018: Acta Oto-laryngologica
Lilian Bostlund Olsen, Sára Larsen, Jens Højberg Wanscher, Christian Emil Faber, Jonas Jeppesen
INTRODUCTION: The aim of this study was to report the frequency and management of postoperative wound infections and to investigate bacteriology and biofilm formation following 653 consecutive cochlear implantations in adults. METHODS: A retrospective file review of 653 consecutive adult cochlear implantations between 1994 and 2015 at the Department of Otorhinolaryngology at Odense University Hospital. A reporting consensus was used to classify infections. RESULTS: The major and minor infection rates were 2% and 8%, respectively...
July 17, 2018: Acta Oto-laryngologica
Jinrang Li, Shizhen Zou, Shiyu Tian
BACKGROUND: Li quick repositioning maneuver for treatment of geotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV) was reported in the literature. OBJECTIVE: The aim of this study is to observe the clinical efficacy of the Li quick repositioning maneuver for the treatment of geotropic HC-BPPV. METHODS: The single-blind method was used to conduct a prospective controlled study on 120 patients with geotropic HC-BPPV from May 2014 to May 2017...
July 17, 2018: Acta Oto-laryngologica
Giuseppe Magliulo, Giannicola Iannella, Marco De Vincentiis, Rosaria Turchetta, Ginevra Portanova, Diletta Angeletti, Patrizia Mancini
BACKGROUND: Recently, the use of transcutaneous bone conduction implants (BCIs) has been increased. However, scarce data about BCI hearing recovery in noise conditions have been reported. OBJECTIVES: To investigate the audiological benefits obtained with transcutaneous BCI-Sophono Alpha System in noise conditions. To evaluate post-implantation clinical outcomes and patient satisfaction levels. MATERIALS AND METHODS: Fourteen patients suffering from conductive or mixed hearing loss implanted with the Sophono Alpha System were evaluated...
June 25, 2018: Acta Oto-laryngologica
Xintai Fan, Ming Xia, Zhe Wang, Hui Zhang, Chengcheng Liu, Na Wang, Lingxiao Hou, Chen Li, Anting Xu
BACKGROUND: As the two most commonly used approaches for cochlear implants (CIs), the round-window insertion (RWI) and cochleostomy are still controversial about which approach is optimal. The lack of visual observation methods makes it difficult to compare the electrode position between them. OBJECTIVES: To evaluate and compare the electrode position between RWI and cochleostomy approaches for CI among young children. MATERIALS AND METHODS: Twenty-four patients (16 male, 8 female) accepting CI and temporal cone-beam computed tomography (CBCT) scan post-operation in our hospital from January 2016 to July 2017 were analyzed retrospectively...
June 23, 2018: Acta Oto-laryngologica
Naoki Sugimoto, Tsuguhisa Nakayama, Yoshiyuki Kasai, Daiya Asaka, Ryoto Mitsuyoshi, Tadao Tsurumoto, Shinya Takaishi, Sachiko Omae, Hiromi Kojima, Yasuhiro Tanaka, Shin-Ichi Haruna
BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is classified into two subtypes: eosinophilic (ECRSwNP) and non-eosinophilic (NECRSwNP). Although the inflammatory patterns of ECRSwNP have been elucidated, NECRSwNP is poorly understood. AIMS/OBJECTIVES: The metalloproteinase ADAM-like decysin 1 (ADAMDEC1) has been reported to play a role in the early stages of the inflammatory response. We investigated the role of ADAMDEC1 in the pathogenesis of CRSwNP...
June 23, 2018: Acta Oto-laryngologica
Rubiliza Onofre, Seung Cheol Ha, Chan Joo Yang, Hwan Seo Lee, Je Yeon Lee, Myung Hoon Yoo, Jun Woo Park, Byung Chul Kang, Hong Ju Park
BACKGROUND: Although CT has been used widely, the role of preoperative CT findings including other factors in tympanoplasty has not been elucidated comprehensively. AIMS/OBJECTIVES: To evaluate relationship of CT findings with other factors and audiological results in type 1 tympanoplasty. MATERIAL AND METHODS: A cohort of consecutive 175 patients with type 1 tympanoplasty was enrolled. Addition of mastoidectomy was based on the presence of soft tissue in antrum on CT...
June 23, 2018: Acta Oto-laryngologica
Maurizio Barbara, Chiara Filippi, Edoardo Covelli, Luigi Volpini, Simonetta Monini
OBJECTIVES: To evaluate long-term benefits of a totally implantable active middle ear implant (AMEI) that has been used in a single implanting center for over 10 years. METHODS: Forty-one subjects who underwent implantation with an Esteem® AMEI during a 10-years period were evaluated on the auditory benefits, as derived from pure tone and speech audiometry tests. The analysis included a comparison with a conventional hearing aid, the problematics related to the battery duration and surgical replacement and, finally, the complication rate...
May 31, 2018: Acta Oto-laryngologica
David Schwarz, Jan Christoffer Luers, Karl Bernd Huttenbrink, Konrad Johannes Stuermer
BACKGROUND: The surgical treatment of acquired post-inflammatory atresia of the external auditory canal (EAC) is challenging. Based on the long-term surgical experience, a modified split skin graft technique has been established at our clinic. AIMS/OBJECTIVES: The aim was to evaluate the clinical and audiological data and patient satisfaction after performing meatoplasty. MATERIAL AND METHODS: In total, 16 patients were included who underwent intraoperative enlargement of the bony EAC, resection of the fibrotic scar tissue, reconstruction with split skin grafts and splinting of the anterior tympanomeatal angle in the period of 2004-2016...
May 31, 2018: Acta Oto-laryngologica
Cheng-Kai Gao, Yan-Fei Li, Lu Wang, Xiao-Yan Han, Ting Wu, Fang-Fang Zeng, Xiang-Ping Li
OBJECTIVES: To assess the differences in Reflux Finding Score (RFS) between the genders and determine the suitable RFS threshold for diagnosing laryngopharyngeal reflux disease (LPRD) in each gender. METHODS: Asymptomatic volunteers and patients with LPRD, confirmed with an oropharyngeal Dx-pH monitoring system, were included. All study subjects underwent transnasal flexible fiber-optic video laryngoscopy. Reliability was assessed with intra-class correlation coefficients (ICCs) and Bland-Altman plots...
May 31, 2018: Acta Oto-laryngologica
Lars Sivars, David Landin, Marzia Rizzo, Linnea Haeggblom, Cinzia Bersani, Eva Munck-Wikland, Anders Näsman, Tina Dalianis, Linda Marklund
BACKGROUND: Distinguishing branchial cleft cysts (BCCs) from cystic metastases of a human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma (OPSCC) is challenging. Fine needle aspirates (FNAs) from cystic metastasis may be non-representative, while reactive squamous cells from BCC can be atypic. Based on cytology and with the support of HPV DNA positivity many centers treat cystic metastasis oncological and thus patients are spared neck dissection. To do so safely, one must investigate whether HPV DNA and p16INK4a overexpression is found exclusively in cystic metastases and not in BCC...
May 15, 2018: Acta Oto-laryngologica
Yoshihiko Kumai, Momoko Ise, Satoru Miyamaru, Yorihisa Orita
OBJECTIVES: To determine the efficacy of delayed transmastoid facial nerve decompression in patients with Ramsay Hunt Syndrome (RHS) presenting with complete facial paralysis. METHODS: Twenty-five RHS patients with complete facial nerve paralysis presenting electroneuronographic (ENoG) degeneration ≥90% underwent transmastoid facial nerve decompression more than 3 weeks after the onset of paralysis. The principal features measured were 12 months pre- and post-operative House-Brackmann (HB) grades and the presence of a direct intraoperative neural response (INR) prior to decompression procedure...
May 15, 2018: Acta Oto-laryngologica
Jin Su Park, So Yean Kim, Min-Beom Kim
OBJECTIVE: To evaluate the effects of intratympanic steroid injection (ITS) in light cupula. METHODS: A total of 47 patients showing persistent geotropic direction-changing positional nystagmus with null point (light cupula) were randomly classified into three groups: ITS (n = 15), vestibular suppressant (VS, n = 16) and canalith repositioning procedure (CRP, n = 16). Positional nystagmus and dizziness severity by dizziness handicap inventory (DHI) and visual analogue scale (VAS) were conducted before and 3 d and 1 week after first treatment to compare the effect of each treatment...
May 15, 2018: Acta Oto-laryngologica
Leif Erik Walther, Jana Wulfes, Alexander Blödow, Rüdiger Kniep
OBJECTIVES: To investigate morphology changes of artificial otoconia (CGC) in the presence of magnesium during growth under in vitro conditions. METHODS: Investigating human otoconia by environmental scanning electron microscope and determining their magnesium content by energy-dispersive X-ray microanalysis (EDX). Comparing structural and morphological data of human and artificial otoconia (CGC, Ca1 Mg0 ) without and with magnesium substitution (Ca1-x Mgx ). RESULTS: EDX- and X-ray data reveals that the inorganic component in human otoconia consists of calcite containing a minor amount of magnesium substitution (Ca1-x Mgx )...
May 15, 2018: Acta Oto-laryngologica
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