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Acta Oto-laryngologica

Edoardo Covelli, Khaled Altabaa, Benjamin Verillaud, Domitille Camous, Charlotte Hautefort, Maurizio Barbara, Philippe Herman, Romain Kania
BACKGROUND: Idiopathic sudden sensorineural hearing loss (ISSNHL) is defined as a decline in hearing affecting three or more frequencies by 30 dB Objective: The aim of this study was to evaluate the results of intratympanic steroids as a salvage treatment for severe ISSNHL. MATERIALS AND METHODS: A regimen of three IT steroid injections was offered to patients who failed a 7-days intravenous steroid treatment. Eighty-four patients underwent IT salvage treatment (IT group)...
October 31, 2018: Acta Oto-laryngologica
Nasrin Yazdani, Armita Kakavand Hamidi, Negin Soroush, Neda Jalili, Aida Vahidi, Nakisa Zarabi Ahrabi, Ardavan Tajdini, Mahsa Amoli
BACKGROUND: Sudden sensorineural hearing loss (SSNHL) causes the loss of hearing of 30 dB or greater on at least three contiguous frequencies. It is known to be a multifactorial disease which the exact cause is unknown, rendering it as an idiopathic disorder of patients. AIMS/OBJECTIVES: This study aims to shed further light on pathogenesis of this disease by studying the association between eNOS gene Glu298Asp polymorphism and VDR gene FokI polymorphism with SSNHL in Iranian population...
October 24, 2018: Acta Oto-laryngologica
Maximilian Linxweiler, Jan Philipp Kühn, Mathias Wagner, Basel Al Kadah, Bernhard Schick
BACKGROUND: Tonsillectomy is one of the most frequent operations in otorhinolaryngology being associated with intense post-operative pain and an impairment of swallowing and speech. AIMS: To determine whether wound sealing with a local mucosal flap can improve patient rehabilitation. MATERIALS AND METHODS: The study was designed as a prospective, randomized, monocentric, controlled clinical trial including 100 patients. Patients were operated on using either conventional extracapsular tonsillectomy (n = 50) or a modified technique with a local mucosal flap prepared from the posterior surface of the tonsil (n = 50)...
October 24, 2018: Acta Oto-laryngologica
Takahito Kondo, Kiyoaki Tsukahara, Naoki Yoshizawa, Isaku Okamoto, Ray Motohashi, Masaki Nomoto, Yasuaki Katsube, Masanori Yatomi, Takashi Iwasawa, Kenji Hanyu, Yasuo Ogawa
BACKGROUND: We devised an advanced pectoral flap (APF) to prevent anastomotic leak after total pharyngolaryngectomy (TPL) and free jejunal reconstruction (FJR) in patients with hypopharyngeal or laryngeal carcinoma. The APF alleviates tension on the skin in the neck, reduces the subcutaneous dead space, and promotes adhesion between the neck skin and the anastomosis. OBJECTIVE: To investigate whether an APF is effective for prevention of anastomotic leak associated with TPL/FJR...
September 27, 2018: Acta Oto-laryngologica
Yasuo Ogawa, Koji Otsuka, Taro Inagaki, Noriko Nagai, Shigeto Itani, Takahito Kondo, Michihiro Kohno, Mamoru Suzuki
OBJECTIVE: The vestibular evoked myogenic potential (VEMP) is associated with otolithic afferents and can be used to evaluate the function of the saccule and utricle. In this study, we compared cervical VEMP evoked by stimulation with Air-conducted sound (ACS) and bone-conducted vibration (BCV) to the forehead and investigated whether BCV can be used as a substitute for ACS. METHODS: Data were obtained from 33 patients with vestibular schwannoma. Vestibular examinations were performed preoperatively...
September 27, 2018: Acta Oto-laryngologica
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September 2018: Acta Oto-laryngologica
Tae Su Kim, Hyun Woo Lim, Chan Joo Yang, Yong Han Kim, Woo Ri Choi, Yeh Ree Kim, Jun Woo Park, Byung Chul Kang, Hong Ju Park
BACKGROUND: The peak head velocity influences on the video head impulse test (vHIT) results, but it has been not known how much the difference is. AIMS: To evaluate the clinical evidence for the superiority of high-velocity compared to low-velocity vHIT. MATERIAL AND METHODS: vHIT was performed in 30 patients with vestibular neuritis using two peak head velocities (mean 80 vs. 240°/s). vHIT gains and parameters of corrective saccades (CSs) were compared...
September 2018: Acta Oto-laryngologica
Jinrang Li, Shizhen Zou, Shiyu Tian
BACKGROUND: Li quick repositioning maneuver for treatment of geotropic horizontal canal benign paroxysmal positional vertigo (HC-BPPV) was reported in the literature. OBJECTIVE: The aim of this study is to observe the clinical efficacy of the Li quick repositioning maneuver for the treatment of geotropic HC-BPPV. METHODS: The single-blind method was used to conduct a prospective controlled study on 120 patients with geotropic HC-BPPV from May 2014 to May 2017...
September 2018: Acta Oto-laryngologica
Giuseppe Magliulo, Giannicola Iannella, Marco De Vincentiis, Rosaria Turchetta, Ginevra Portanova, Diletta Angeletti, Patrizia Mancini
BACKGROUND: Recently, the use of transcutaneous bone conduction implants (BCIs) has been increased. However, scarce data about BCI hearing recovery in noise conditions have been reported. OBJECTIVES: To investigate the audiological benefits obtained with transcutaneous BCI-Sophono Alpha System in noise conditions. To evaluate post-implantation clinical outcomes and patient satisfaction levels. MATERIALS AND METHODS: Fourteen patients suffering from conductive or mixed hearing loss implanted with the Sophono Alpha System were evaluated...
September 2018: Acta Oto-laryngologica
Xintai Fan, Ming Xia, Zhe Wang, Hui Zhang, Chengcheng Liu, Na Wang, Lingxiao Hou, Chen Li, Anting Xu
BACKGROUND: As the two most commonly used approaches for cochlear implants (CIs), the round-window insertion (RWI) and cochleostomy are still controversial about which approach is optimal. The lack of visual observation methods makes it difficult to compare the electrode position between them. OBJECTIVES: To evaluate and compare the electrode position between RWI and cochleostomy approaches for CI among young children. MATERIALS AND METHODS: Twenty-four patients (16 male, 8 female) accepting CI and temporal cone-beam computed tomography (CBCT) scan post-operation in our hospital from January 2016 to July 2017 were analyzed retrospectively...
September 2018: Acta Oto-laryngologica
Naoki Sugimoto, Tsuguhisa Nakayama, Yoshiyuki Kasai, Daiya Asaka, Ryoto Mitsuyoshi, Tadao Tsurumoto, Shinya Takaishi, Sachiko Omae, Hiromi Kojima, Yasuhiro Tanaka, Shin-Ichi Haruna
BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is classified into two subtypes: eosinophilic (ECRSwNP) and non-eosinophilic (NECRSwNP). Although the inflammatory patterns of ECRSwNP have been elucidated, NECRSwNP is poorly understood. AIMS/OBJECTIVES: The metalloproteinase ADAM-like decysin 1 (ADAMDEC1) has been reported to play a role in the early stages of the inflammatory response. We investigated the role of ADAMDEC1 in the pathogenesis of CRSwNP...
September 2018: Acta Oto-laryngologica
Rubiliza Onofre, Seung Cheol Ha, Chan Joo Yang, Hwan Seo Lee, Je Yeon Lee, Myung Hoon Yoo, Jun Woo Park, Byung Chul Kang, Hong Ju Park
BACKGROUND: Although CT has been used widely, the role of preoperative CT findings including other factors in tympanoplasty has not been elucidated comprehensively. AIMS/OBJECTIVES: To evaluate relationship of CT findings with other factors and audiological results in type 1 tympanoplasty. MATERIAL AND METHODS: A cohort of consecutive 175 patients with type 1 tympanoplasty was enrolled. Addition of mastoidectomy was based on the presence of soft tissue in antrum on CT...
September 2018: Acta Oto-laryngologica
Maurizio Barbara, Chiara Filippi, Edoardo Covelli, Luigi Volpini, Simonetta Monini
OBJECTIVES: To evaluate long-term benefits of a totally implantable active middle ear implant (AMEI) that has been used in a single implanting center for over 10 years. METHODS: Forty-one subjects who underwent implantation with an Esteem® AMEI during a 10-years period were evaluated on the auditory benefits, as derived from pure tone and speech audiometry tests. The analysis included a comparison with a conventional hearing aid, the problematics related to the battery duration and surgical replacement and, finally, the complication rate...
September 2018: Acta Oto-laryngologica
David Schwarz, Jan Christoffer Luers, Karl Bernd Huttenbrink, Konrad Johannes Stuermer
BACKGROUND: The surgical treatment of acquired post-inflammatory atresia of the external auditory canal (EAC) is challenging. Based on the long-term surgical experience, a modified split skin graft technique has been established at our clinic. AIMS/OBJECTIVES: The aim was to evaluate the clinical and audiological data and patient satisfaction after performing meatoplasty. MATERIAL AND METHODS: In total, 16 patients were included who underwent intraoperative enlargement of the bony EAC, resection of the fibrotic scar tissue, reconstruction with split skin grafts and splinting of the anterior tympanomeatal angle in the period of 2004-2016...
September 2018: Acta Oto-laryngologica
Cheng-Kai Gao, Yan-Fei Li, Lu Wang, Xiao-Yan Han, Ting Wu, Fang-Fang Zeng, Xiang-Ping Li
OBJECTIVES: To assess the differences in Reflux Finding Score (RFS) between the genders and determine the suitable RFS threshold for diagnosing laryngopharyngeal reflux disease (LPRD) in each gender. METHODS: Asymptomatic volunteers and patients with LPRD, confirmed with an oropharyngeal Dx-pH monitoring system, were included. All study subjects underwent transnasal flexible fiber-optic video laryngoscopy. Reliability was assessed with intra-class correlation coefficients (ICCs) and Bland-Altman plots...
September 2018: Acta Oto-laryngologica
Lars Sivars, David Landin, Marzia Rizzo, Linnea Haeggblom, Cinzia Bersani, Eva Munck-Wikland, Anders Näsman, Tina Dalianis, Linda Marklund
BACKGROUND: Distinguishing branchial cleft cysts (BCCs) from cystic metastases of a human papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma (OPSCC) is challenging. Fine needle aspirates (FNAs) from cystic metastasis may be non-representative, while reactive squamous cells from BCC can be atypic. Based on cytology and with the support of HPV DNA positivity many centers treat cystic metastasis oncological and thus patients are spared neck dissection. To do so safely, one must investigate whether HPV DNA and p16INK4a overexpression is found exclusively in cystic metastases and not in BCC...
September 2018: Acta Oto-laryngologica
Yoshihiko Kumai, Momoko Ise, Satoru Miyamaru, Yorihisa Orita
OBJECTIVES: To determine the efficacy of delayed transmastoid facial nerve decompression in patients with Ramsay Hunt Syndrome (RHS) presenting with complete facial paralysis. METHODS: Twenty-five RHS patients with complete facial nerve paralysis presenting electroneuronographic (ENoG) degeneration ≥90% underwent transmastoid facial nerve decompression more than 3 weeks after the onset of paralysis. The principal features measured were 12 months pre- and post-operative House-Brackmann (HB) grades and the presence of a direct intraoperative neural response (INR) prior to decompression procedure...
September 2018: Acta Oto-laryngologica
Jin Su Park, So Yean Kim, Min-Beom Kim
OBJECTIVE: To evaluate the effects of intratympanic steroid injection (ITS) in light cupula. METHODS: A total of 47 patients showing persistent geotropic direction-changing positional nystagmus with null point (light cupula) were randomly classified into three groups: ITS (n = 15), vestibular suppressant (VS, n = 16) and canalith repositioning procedure (CRP, n = 16). Positional nystagmus and dizziness severity by dizziness handicap inventory (DHI) and visual analogue scale (VAS) were conducted before and 3 d and 1 week after first treatment to compare the effect of each treatment...
September 2018: Acta Oto-laryngologica
Leif Erik Walther, Jana Wulfes, Alexander Blödow, Rüdiger Kniep
OBJECTIVES: To investigate morphology changes of artificial otoconia (CGC) in the presence of magnesium during growth under in vitro conditions. METHODS: Investigating human otoconia by environmental scanning electron microscope and determining their magnesium content by energy-dispersive X-ray microanalysis (EDX). Comparing structural and morphological data of human and artificial otoconia (CGC, Ca1 Mg0 ) without and with magnesium substitution (Ca1-x Mgx ). RESULTS: EDX- and X-ray data reveals that the inorganic component in human otoconia consists of calcite containing a minor amount of magnesium substitution (Ca1-x Mgx )...
September 2018: Acta Oto-laryngologica
Beier Qi, Peng Liu, Xin Gu, Ruijuan Dong, Bo Liu
BACKGROUND: Categorical perception (CP) of lexical tones was examined in normal hearing (NH) people, but it was unclear whether lexical tones can be perceived categorically in sensorineural hearing loss (SNHL) people. OBJECTIVES: To explore the characteristic of lexical tone perception in native Mandarin speakers with SNHL. MATERIALS AND METHODS: Three types of continuum (Tone1/Tone2, Tone1/Tone4 and Tone2/Tone3) were constructed and each of them includes 15 stimuli which were resynthesized by applying the pitch-synchronous overlap and add (PSOLA) method implemented in Praat to the same Mandarin syllable, /a/, with a high-level tone produced by a female speaker...
September 2018: Acta Oto-laryngologica
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