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Acta Oto-laryngologica

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https://www.readbyqxmd.com/read/28643583/hemodynamic-stability-during-laryngeal-electromyography-procedures
#1
Yi-An Lu, Yu-Cheng Pei, Alice Mk Wong, Hui-Chen Chiang, Tuan-Jen Fang
BACKGROUND: Laryngeal electromyography (LEMG) is accepted as safe, with minimal side effects. However, patient hemodynamic stability, during these procedures, has not been reported. This study aimed to investigate the hemodynamics in patients undergoing LEMG and determine the risk factors for hemodynamic changes. METHODS: We recruited 89 consecutive patients who underwent LEMG. Baseline and postprocedural changes in vital signs were analyzed. RESULTS: Diastolic blood pressure (DBP) increased from 75...
June 23, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28643576/sensory-organization-test-principally-reflects-utricular-function
#2
Jia Liu, Renhong Zhou, Bo Liu, Yangming Leng, Jingjing Liu, Dongdong Liu, Su-Lin Zhang, Wei-Jia Kong
CONCLUSION: Our study showed that sensory organization test (SOT) could principally reflect utricular function, and our cut-score of VEST ratio (the indicator of inputs from the vestibular system in balance performance) in SOT could help to screen patients with unilateral peripheral vestibular dysfunction in non-fallers. OBJECTIVES: We aimed to know SOT reflects the function of which vestibular end organs and to assess the possibility of screening patients with peripheral vestibular dysfunction in non-fall population by means of SOT...
June 23, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28643540/correction-to-chen-l-et%C3%A2-al-molecular-mechanisms-underlying-the-protective-effects-of-hydrogen-saturated
#3
(no author information available yet)
No abstract text is available yet for this article.
June 23, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28643534/transplantation-of-mouse-induced-pluripotent-stem-cells-into-the-cochlea-for-the-treatment-of-sensorineural-hearing-loss
#4
Jing Chen, Lina Guan, Hengtao Zhu, Shan Xiong, Liang Zeng, Hongqun Jiang
CONCLUSION: Mouse-induced pluripotent stem cells (iPSCs) could differentiate into hair cell-like cells and spiral ganglion-like cells after transplantation into mouse cochleae, but it cannot improve the auditory brain response (ABR) thresholds in short term. OBJECTIVE: To evaluate the potential of iPSCs for use as a source of transplants for the treatment of sensorineural hearing loss (SNHL). METHODS: Establishing SNHL mice model, then injecting the iPSCs or equal volume DMEM basic medium into the cochleae, respectively...
June 23, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28641038/interaction-of-tinnitus-suppression-and-hearing-ability-after-cochlear-implantation
#5
Qian Wang, Jia-Nan Li, Guan-Xiong Lei, Dai-Shi Chen, Wei-Ze Wang, Ai-Ting Chen, Meng-Di Mong, Sun Li, Qing-Shan Jiao, Shi-Ming Yang
OBJECTIVES: To study the postoperative impact of cochlear implants (CIs) on tinnitus, as well as the impact of tinnitus on speech recognition with CI switched on. METHODS: Fifty-two postlingual deafened CI recipients (21 males and 31 females) were assessed using an established Tinnitus Characteristics Questionnaire and Tinnitus Handicap Inventory (THI) before and after cochlear implantation. The tinnitus loudness was investigated when CI was switched on and off in CI recipients with persistent tinnitus...
June 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28599589/expressions-of-trpvs-in-the-cholesteatoma-epithelium
#6
Ba Hung Do, Hiroki Koizumi, Toyoaki Ohbuchi, Rintaro Kawaguchi, Hideaki Suzuki
OBJECTIVE: We have recently proposed a hypothesis that acid leakage through the cholesteatoma epithelium mediates bone resorption in middle ear cholesteatoma. In the present study, we investigated the expressions of transient receptor potential vanilloid (TRPV) channels, which have been shown to play roles in the regulation of epidermal barrier function, in the cholesteatoma epithelium in comparison with the normal skin. METHODS: Cholesteatoma epithelium and postauricular skin were collected from 17 patients with primary acquired middle ear cholesteatoma who underwent tympanomastoidectomy...
June 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28598766/tonsil-surgery-in-sweden-2013-2015-indications-surgical-methods-and-patient-reported-outcomes-from-the-national-tonsil-surgery-register
#7
Niclas Hallenstål, Ola Sunnergren, Elisabeth Ericsson, Claes Hemlin, Anne-Charlotte Hessén Söderman, Pia Nerfeldt, Erik Odhagen, Marie Ryding, Joacim Stalfors
AIM: To describes how tonsil surgery was performed in Sweden from 2013 to 2015 with data from the National Tonsil Surgery Registry in Sweden (NTSRS). METHOD: The registry collects data from both professionals and patients through questionnaires. A total of 33,870 tonsil surgeries were analysed, comprising approximately 80% of all tonsil surgeries in Sweden from 2013 to 2015. RESULTS: The two most common procedures were tonsillectomy (41%) and tonsillotomy with adenoidectomy (38%)...
June 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28598713/robot-assisted-endoscope-guidance-versus-manual-endoscope-guidance-in-functional-endonasal-sinus-surgery-fess
#8
Klaus Wolfgang Eichhorn, Ralf Westphal, Markus Rilk, Carsten Last, Friedrich Bootz, Friedrich Wahl, Mark Jakob, Thorsten Send
BACKGROUND: Having one hand occupied with the endoscope is the major disadvantage for the surgeon when it comes to functional endoscopic sinus surgery (FESS). Only the other hand is free to use the surgical instruments. Tiredness or frequent instrument changes can thus lead to shaky endoscopic images. METHODS: We collected the pose data (position and orientation) of the rigid 0° endoscope and all the instruments used in 16 FESS procedures with manual endoscope guidance as well as robot-assisted endoscope guidance...
June 9, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28587562/a-method-to-induce-human-cortical-long-term-potentiation-by-acoustic-stimulation
#9
Guanxiong Lei, Zeqi Zhao, Yalan Li, Liming Yu, Xin Zhang, Yan Yan, Xiaoyan Ma, Qian Wang, Keshuang Wang, Duo Zhang, Weidong Shen, Yuehua Qiao, Shiming Yang
OBJECT: Acoustic stimulation induced LTP in the human auditory cortex was successfully recorded for the first time by electroencephalography (EEG) using a stimulus of 1 kHz pure-tone in 2005. However, it was barely reproduced, given considerable challenges to reliably elicit and accurately record the enhanced potentials in vivo. The purpose of this paper was to explore whether acoustic stimuli other than 1 kHz pure-tone could generate LTP or not. MEASURES: To answer this question, we proposed a tetanic-stimulation paradigm of pure-tones, narrow-band noises (NBNs) and white noise (WN) to elicit LTP in human subjects...
June 7, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28554254/implementation-of-the-hyaluronic-acid-fat-graft-myringoplasty-technique-pitfalls-and-lessons-learned
#10
Nienke Grotenhuis, Jan Pieter Koopman, J Kruyt, Laura Kiki Rothuizen, Rachel Knevel, Henk Blom
BACKGROUND: Myringoplasty is a common procedure in otorhinolaryngology. Many techniques with different complications and outcomes have been described, one of which is hyaluronic acid fat graft myringoplasty (HAFGM). This technique, as proposed by Saliba, uses fat tissue and hyaluronic acid discs. The technique is relatively fast with a high success rate and low complications. However, what outcomes can be expected when performed by other surgeons? In this paper, we report on the technique's success in our own hands...
May 29, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28549396/molecular-mechanisms-underlying-the-protective-effects-of-hydrogen-saturated-saline-on-noise-induced-hearing-loss
#11
Liwei Chen, Mingkun Han, Yan Lu, Daishi Chen, Xuejun Sun, Shiming Yang, Wei Sun, Ning Yu, Suoqiang Zhai
OBJECTIVES: This study aimed to explore the molecular mechanism of the protective effects of hydrogen-saturated saline on NIHL. METHODS: Guinea pigs were divided into three groups: hydrogen-saturated saline; normal saline; and control. For saline administration, the guinea pigs were given daily abdominal injections 3 d before and 1 h before noise exposure. ABR were tested to examine cochlear physiology changes. The changes of 8-hydroxy-desoxyguanosine (8-HOdG), interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor-α (TNF-α), intercellular cell adhesion molecule-1 (ICAM-1) and high mobility group box-1 protein (HMGB1) in the cochlea were also examined...
May 26, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28549389/correction-to-huang-h-et%C3%A2-al-m2-polarized-tumour-associated-macrophages-in-stroma-correlate-with-poor-prognosis-and-epstein-barr-viral-infection-in-nasopharyngeal-carcinoma
#12
(no author information available yet)
No abstract text is available yet for this article.
May 26, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28541825/surgical-treatment-of-vertigo-in-cochlear-implantees-by-electrode-resealing
#13
Dania Karimi, Philipp Mittmann, Arneborg Ernst, Ingo Todt
CONCLUSION: Our present findings demonstrate that resealing to cover the electrode is an effective method to treat vertigo after CI. An insufficient cochleostomy sealing can be regarded as a cause of postoperatively newly occuring vertigo after CI. A transtympanic revision is a promising treatment option in cases of post-operative dizziness. Intoduction: A well-known and frequently reported complication after cochlear implantation is the appearance of postoperative vertigo symptoms. The aim of the present study was to observe if the postoperatively new occurrence of vertigo can be treated by resealing of the round window patch after cochlear implantation...
May 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28541766/the-clinical-utility-of-vestibular-autorotation-test-in-patients-with-vestibular-migraine
#14
Yogun Thungavelu, Wei Wang, Peng Lin, Taisheng Chen, Kaixu Xu
OBJECTIVE: To investigate the characteristics and clinical utility of vestibular autorotation test (VAT) in patients with vestibular migraine. METHODS: This study included two groups, an experimental group (441 patients) and a control group (65 healthy subjects). Both groups undertook VAT; the parameters evaluated were horizontal gain/phase, vertical gain/phase and asymmetry. The differences in VAT results between the two groups were investigated. RESULTS: There were no statistical differences between the VAT data of the control group when compared to the reference value from the manufacturer (p > ...
May 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28537142/perceived-direction-of-gravity-and-the-body-axis-during-static-whole-body-roll-tilt-in-healthy-subjects
#15
Atsushi Tamura, Yoshiro Wada, Takuo Inui, Akihiro Shiotani
OBJECTIVE: We used the subjective visual vertical (SVV) and two different subjective visual body axis (SVBA) methods to quantify roll-tilt perception under gravity, and investigated the characteristics of these methods during static roll-tilt. In addition, we independently developed a compact device to facilitate evaluation of SVBA in different gravitational environments. METHODS: Ten male volunteers participated in this study. We created a roll-tilt environment using a flight simulator in a dark room...
May 24, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28537107/clinical-and-audiological-short-term-and-long-term-outcomes-of-fat-graft-myringoplasty
#16
Johan Knutsson, Annika Kahlin, Magnus von Unge
INTRODUCTION: Results of fat graft myringoplasty are often reported with only short-term follow-up. Audiological results are less commonly reported, as well as long-term follow-up results. MATERIALS AND METHODS: One hundred consecutive patients scheduled for fat graft myringoplasty were included in a prospective cohort study. Clinical and audiological outcomes were assessed at six weeks and one year postoperatively. RESULTS: Perforation sizes ranged from 0...
May 24, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28537102/cisplatin-induced-metabolome-changes-in-serum-an-experimental-approach-to-identify-markers-for-ototoxicity
#17
Pernilla Videhult Pierre, Jakob Haglöf, Birgitta Linder, Mikael K R Engskog, Torbjörn Arvidsson, Curt Pettersson, Anette Fransson, Göran Laurell
BACKGROUND: Ototoxicity from treatment with the anticancer drug cisplatin remains a clinical problem. A wide range of intracellular targets of cisplatin has been found in vivo. AIM: To investigate cisplatin-induced change of the serum metabolite profile and its association with ototoxicity. MATERIAL AND METHODS: Guinea pigs (n = 14) were treated with cisplatin (8 mg/kg b.w., i.v.) 30 min after administration of the otoprotector candidate sodium thiosulfate (group STS; n = 7) or sodium chloride (group NaCl; n = 7)...
May 24, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28537101/clinical-findings-in-25-patients-with-sinonasal-or-nasopharyngeal-extramedullary-plasmacytoma-in-a-four-decade-single-centre-series
#18
Seija Inkeri Vento, Pauli Vähämurto, Kaija Silventoinen, Marja-Liisa Karjalainen-Lindsberg, Susanna Mannisto, Sirpa Leppä, Antti Aarni Mäkitie
OBJECTIVES: Extramedullary plasmacytoma in the sinonasal tract or nasopharynx is rare. The aim of the study was to review data on symptoms, clinical findings, treatment and follow-up of plasmacytomas in the sinonasal and nasopharyngeal regions in order to delineate the main clinical characteristics and the optimal management. METHOD: Twenty-five patients with sinonasal or nasopharyngeal plasmacytoma, diagnosed and treated at the Helsinki University Hospital during a 39-year period from 1975 to 2013 were retrospectively reviewed...
May 24, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28532297/preoperative-assessment-of-stapes-implantations-of-the-vibrant-soundbridge-for-congenital-aural-atresia-patients
#19
Danni Wang, Demin Han, Shouqin Zhao, Ran Ren, Jiyong Dong
OBJECTIVE: The objective of this study is to retrospectively analyze the imaging characteristics of patients with congenital aural atresia who underwent Vibrant Soundbridge implantation, and to investigate the importance of preoperative evaluation of vibroplasty. MATERIALS AND METHODS: The study included 16 patients with bilateral congenital aural atresia aged 6-25 years (mean age, 14.7 years). All patients underwent Vibrant Soundbridge implantations. RESULTS: Among the 16 patients, 15 successfully underwent stapes implantation...
May 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28504000/factors-associated-with-successful-decannulation-in-pediatric-tracheostomy-patients
#20
Nozomi Takahashi, Kenichi Takano, Hiroaki Mitsuzawa, Maokoto Kurose, Tetsuo Himi
OBJECTIVES: To investigate the outcome of pediatric tracheostomy and identify predictive factors for successful decannulation. METHODS: We performed a retrospective chart review of a series of 42 consecutive patients of less than 24 months of age who underwent a tracheostomy between 2012 and 2015. RESULTS: Successful decannulation was achieved in 11 patients (26%). Thirty-one patients (74%) remained tracheostomy-dependent. Of the 11 patients who were successfully decannulated, 10 (91%) had only structural disorders and nine (82%) were able to walk unassisted; importantly, nine (82%) were able to swallow following decannulation...
May 14, 2017: Acta Oto-laryngologica
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