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Acta Oto-laryngologica

Paul van den Broek
No abstract text is available yet for this article.
October 25, 2016: Acta Oto-laryngologica
Masaya Takumida, Hiroshi Takumida, Matti Anniko
CONCLUSION: Gastric type H(+),K(+)-ATPase in the vestibular end organs may be of importance for K(+) circulation and may also be related to pH regulation in vestibular end organs and endolymphatic sac. OBJECTIVE: To analyze the expression of gastric-type H(+),K(+)-ATPase in normal mouse vestibular end organs. METHODS: 8 weeks old CBA/J mice were used in this study. The presence of gastric-type H(+),K(+)-ATPase α and β in the vestibular end organs, viz...
October 21, 2016: Acta Oto-laryngologica
Nagisa Sugaya, Miki Arai, Fumiyuki Goto
CONCLUSIONS: Improvement in sleep, emotional distress, and health-related quality-of-life (QoL) accompanied the improvement in dizziness symptoms after vestibular rehabilitation. Persistent sleep disturbance could prevent improvements in self-perceived handicap due to chronic dizziness and anxiety. OBJECTIVE: The present study investigated prospectively the effects of intervention for dizziness (vestibular rehabilitation) on sleep disturbance, and the relationship between improvements in dizziness symptoms and improvements in sleep disturbance after the intervention...
October 19, 2016: Acta Oto-laryngologica
Rika Kobayashi, Koichi Tsunoda, Rumi Ueha, Yoko Fujimaki, Takaharu Nito, Tatsuya Yamasoba
CONCLUSIONS: It is considered that a regimen combining pharmacologic management and lifestyle modifications is the most effective treatment for laryngeal granulomas caused by GER. OBJECTIVES: This study compared the results of the combination therapy and surgery to determine the best treatment of laryngeal granuloma caused by gastro-esophageal reflux in 51 patients. METHODS: Prospective study. RESULTS: In the conservative treatment group, the CR rate was 89...
October 19, 2016: Acta Oto-laryngologica
Jorge Rey-Martinez, Leigh McGarvie, Nicolás Pérez-Fernández
CONCLUSION: The obtained simulations support the underlying hypothesis that the hydrostatic caloric drive is dissipated by local convective flow in a hydropic duct. OBJECTIVE: To develop a computerized model to simulate and predict the internal fluid thermodynamic behavior within both normal and hydropic horizontal ducts. METHODS: This study used a computational fluid dynamics software to simulate the effects of cooling and warming of two geometrical models representing normal and hydropic ducts of one semicircular horizontal canal during 120 s...
October 14, 2016: Acta Oto-laryngologica
Lorenz Kadletz, Elisabeth Enzenhofer, Ulana Kotowski, Gabriela Altorjai, Gregor Heiduschka
CONCLUSION: On the one hand, AZD5582, an inhibitor of inhibitor of apoptosis family proteins (IAP), leads to cellular growth arrest and induction of apoptosis in head and neck squamous cell carcinoma (HNSCC) cell lines. On the other hand, it is a viable candidate for combination therapy with irradiation. OBJECTIVES: The aim and purpose of this study was to evaluate the effects of AZD5582 on HNSCC cell lines. METHODS: HNSCC cell lines SCC25, Cal27, and FaDu were used for all cell culture experiments...
October 14, 2016: Acta Oto-laryngologica
Beier Qi, Ziye Liu, Xin Gu, Bo Liu
CONCLUSION: Mandarin-speaking adults can use the Fine Structure Processing (FSP) coding strategy as well as the Continuous Interleaved Sampling (CIS+) coding strategy. No loss in performance was observed after switch-over. Tone identification improves over time with the FSP coding strategy, which is of benefit to tonal-language users. After some time, fine structure was preferred. OBJECTIVE: This study aimed to determine speech perception, tone perception, and the subjective preferences of Mandarin-speaking adults who received the FSP coding strategy, at upgrade from the CIS + coding strategy...
October 5, 2016: Acta Oto-laryngologica
Michihiko Sone, Tadao Yoshida, Satofumi Sugimoto, Kyoko Morimoto, Yuriko Okazaki, Masaaki Teranishi, Shinji Naganawa, Tsutomu Nakashima
CONCLUSIONS: The presence of endolymphatic hydrops (EH) in the vestibule on magnetic resonance imaging (MRI) might be a high-risk factor for complications in cases that are candidates for stapes surgery. OBJECTIVE: Pre-operative detection of EH could be valuable in cases that are candidates for stapes surgery to prevent unpredictable complications following surgery. Pre-operative MRI findings and post-operative findings following stapes surgery were compared to evaluate the efficacy of such MRI evaluation for the management of cases with otosclerosis...
September 27, 2016: Acta Oto-laryngologica
Qian Cai, Honglei Zhu, Taihui Yu, Xiaoming Huang, Faya Liang, Ping Han, Peiliang Lin
CONCLUSION: A high-lying innominate artery (the upper edge of the innominate artery across the anterior midline of the trachea located 2 cm above the suprasternal notch), a rare situation, may produce disturbance to related anterior cervical tracheal surgery and even cause serious complications. OBJECTIVES: High-lying innominate artery is a high risk factor in anterior cervical tracheal surgery. Pre-operative assessment via imaging technique can help to familiarize the artery and reduce the related disturbance to the surgery...
September 27, 2016: Acta Oto-laryngologica
Toshiaki Kikuchi, Ryoukichi Ikeda, Hidetoshi Oshima, Iori Takata, Tetsuaki Kawase, Takeshi Oshima, Yukio Katori, Toshimitsu Kobayashi
CONCLUSIONS: Trans-tympanic plugging of the Eustachian tube (ET) with the silicone plug (Kobayashi Plug) induced long-term effectiveness for over 80% of chronic and severe patulous ET (PET) patients. The New Kobayashi Plug was more effective with fewer complication of plug descent to the pharyngeal orifice. OBJECTIVE: To investigate the effectiveness and complications of trans-tympanic plugging of the ET using a Kobayashi Plug for chronic PET. METHOD: Trans-tympanic plugging of the ET using the Kobayashi Plug was performed for 252 ears of 191 patients...
September 26, 2016: Acta Oto-laryngologica
Ingo Todt, Marlene Mittmann, Arneborg Ernst, Philipp Mittmann
CONCLUSION: Based on this model experiment, a small tip and low volume electrode show lowest intra-cochlear pressure values. Insertional support by a tool minimizes fast pressure changes. Higher electrodes volumes affect slow and fast pressure changes as well. OBJECTIVE: Insertion causing low intra-cochlear pressure is assumed to be important for atraumatic cochlear implant surgery to preserve residual hearing. Cochlear implant electrodes differ in terms of parameters like tip size, length, volume, and technique of insertion...
September 23, 2016: Acta Oto-laryngologica
Johanna Jokela, Aaro Haapaniemi, Antti Mäkitie, Riitta Saarinen
CONCLUSIONS: In most cases, both diagnostic and interventional sialendoscopy are well tolerated under local anaesthesia (LA) or under local anaesthesia with sedation (LAS), with reasonably low patient-reported discomfort. Sialendoscopy can be considered a patient-friendly and relatively painless, gland-preserving, minimally invasive procedure suitable for day surgery. OBJECTIVE: To investigate patient experience and compliance in sialendoscopy under LA/LAS. METHODS: This prospective study was conducted at an academic tertiary-care university hospital...
September 23, 2016: Acta Oto-laryngologica
Anna Dapefrid, Birgitta Lundström, Krister Tano
CONCLUSION: There was a high prevalence of Fusobacterium necrophorum (FN) in patients with chronic tonsillitis in the age group 15-23 years. This indicates that FN might play an important role in the pathogenesis of chronic tonsillitis in this age group, which is also the age group in which chronic or recurrent tonsillitis is most common. OBJECTIVES: The role of FN in patients with acute and chronic tonsillitis is unclear. Thus, this study investigated the occurrence of FN in tonsils of patients with chronic tonsillitis...
September 23, 2016: Acta Oto-laryngologica
Satu Turunen-Taheri, Åsa Skagerstrand, Sten Hellström, Per-Inge Carlsson
CONCLUSIONS: Patients with severe vision impairment in combination with severe-to-profound hearing loss seem to have a higher risk for effects on QoL, including: mobility, the ability to provide self-care and perform usual activities, and levels of anxiety and depression, compared with patients with only severe-to-profound hearing loss. OBJECTIVES: To study the quality-of-life (QoL) and audiological rehabilitation of the severely vision-impaired patient population among adults with severe-to-profound hearing loss in Sweden...
September 23, 2016: Acta Oto-laryngologica
Yangming Leng, Bo Liu, Renhong Zhou, Jingjing Liu, Dongdong Liu, Su-Lin Zhang, Wei-Jia Kong
CONCLUSION: Intra-tympanic dexamethasone injection (ITD) could serve as a first-line intra-tympanic (IT) treatment for Meniere's disease (MD), regardless of hearing level. Even if the response to initial ITD course was unsatisfactory, a repeated course may be beneficial with some patients. OBJECTIVES: This study examined the effect of repeated courses of ITD administered on demand and investigated the possibility of ITD as an initial IT treatment for medically intractable MD patients...
September 21, 2016: Acta Oto-laryngologica
Anni Koskinen, Petri Mattila, Jyri Myller, Matti Penttilä, Juha Silvola, Ismo Alastalo, Heini Huhtala, Maija Hytönen, Sanna Toppila-Salmi
CONCLUSION: In terms of operation time, anesthesia method, and low complication rate, ESS and balloon sinuplasty seemed comparable. The advantages of balloon sinuplasty were shown to be shortness of sick leave, possibility to be performed as an in-office procedure, and lower adhesion formation. BACKGROUND: Endoscopic sinus surgery (ESS) has been considered as a treatment of choice for persistent chronic rhinosinusitis (CRS). During the last decade balloon sinuplasty has been introduced as an alternative technique to dilate the ostium...
September 20, 2016: Acta Oto-laryngologica
Suzuyo Okazaki, Takao Imai, Kayoko Higashi-Shingai, Kazunori Matsuda, Noriaki Takeda, Tadashi Kitahara, Atsuhiko Uno, Arata Horii, Yumi Ohta, Tetsuo Morihana, Chisako Masumura, Suetaka Nishiike, Hidenori Inohara
CONCLUSION: A 30 s observation of geotropic positional nystagmus is sufficient to distinguish persistent geotropic positional nystagmus (PGPN) from transient geotropic positional nystagmus (TGPN) in patients with horizontal canal type of benign paroxysmal positional vertigo (H-BPPV) in ENT office. OBJECTIVE: As a canalith repositioning procedure effectively treats H-BPPV with TGPN, but not PGPN, the differentiation between patients with PGPN and with TGPN is essential...
September 20, 2016: Acta Oto-laryngologica
Keiko Ohno, Yurika Kimura, Yoko Matsuda, Masatoki Takahashi, Motomu Honjyou, Tomio Arai, Takeshi Tsutsumi
CONCLUSION: High levels of IgG4-positive plasma cells were observed in tissue samples from ∼30% of patients with chronic rhinosinusitis who satisfied the comprehensive diagnostic criteria for IgG4-related disease. Detection of increased numbers of IgG4-positive plasma cells in the nasal cavity or paranasal sinuses might not be sufficient to make a diagnosis of IgG4-related rhinosinusitis, and a comprehensive evaluation is required. OBJECTIVES: This study aimed to clarify the clinicopathological characteristics of IgG4-positive plasma cells in patients with chronic rhinosinusitis...
September 20, 2016: Acta Oto-laryngologica
Victoria S Lee, Rebecca M Gold, Sanjay R Parikh
CONCLUSIONS: Pediatric septoplasty may be associated with short-term symptomatic benefit. This benefit may be greater in female patients and equally achievable in young patients and using less invasive surgical approaches. OBJECTIVE: To determine the short-term effect of pediatric septoplasty, which is not routinely performed, on sinus and nasal-specific quality-of-life. METHODS: This study is a retrospective case series of 28 pediatric patients that underwent septoplasty...
September 19, 2016: Acta Oto-laryngologica
Jin Hao, Xinxing Fu, Chunfang Zhang, Xuelian Zhang, Shouqin Zhao, Yongxin Li
CONCLUSIONS: The distortion product otoacoustic emission (DPOAE) amplitudes in diabetics were significantly lower than those in controls when pure tone audiometry (PTA) was within normal limits, implying cochlear function impairment in the early stage of diabetes mellitus. Retrocochlear damage was suggested by elongated wave latencies and the wave interval of auditory brainstem response (ABR) in diabetics. OBJECTIVES: This study aimed to systematically analyze the application of DPOAE in evaluation of the hearing function of diabetics...
September 15, 2016: Acta Oto-laryngologica
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