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Acta Oto-laryngologica

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https://www.readbyqxmd.com/read/28799451/radiological-clinical-and-audiological-evaluation-of-jugular-bulb-vestibular-aqueduct-dehiscence
#1
Asli Tanrivermis Sayit, Muzaffer Elmali, Ozgur Kemal, Yuksel Terzi
OBJECTIVE: The aim of this study is to determine the prevalence of jugular bulb-vestibular aqueduct dehiscence (JBVAD) in patients undergoing temporal bone multidetector computed tomography (MDCT) and assess the relationship between JBVAD and hearing loss with the findings of audiometry. METHODS: About 1503 temporal bone MDCT scans were evaluated for the prevalence of JBVAD. Correlation of the imaging findings and audiometric data was performed. Patients were divided into two groups, those with and those without hearing loss, and were statistically compared...
August 11, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28784038/administering-of-pregabalin-and-acetaminophen-on-management-of-postoperative-pain-in-patients-with-nasal-polyposis-undergoing-functional-endoscopic-sinus-surgery
#2
Ahmad Rezaeian
BACKGROUND: Management of postoperative pain is a common problem in endoscopic sinus surgery. The objective of this study is the evaluation of pregabalin and acetaminophen effects on the management of postoperative pain in patients with nasal polyposis undergoing functional endoscopic sinus surgery (FESS). MATERIALS AND METHODS: In this clinical trial, double-blinded study, 70 patients with nasal polyposis who have indication of FESS were enrolled to this study...
August 8, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28784019/mechanisms-of-electrode-fold-over-in-cochlear-implant-surgery-when-using-a-flexible-and-slim-perimodiolar-electrode-array
#3
Angel Ramos-Macias, Angel R De Miguel, Juan Carlos Falcon-González
OBJECTIVES: This study evaluates the design of a thin perimodiolar cochlear implant electrode array (CI532) and assesses insertion-related rotation and fold-over. METHODS: The study consisted on a cochlear model and temporal bone insertion studies. Twenty insertions were studied, under four different surgical insertion conditions in vitro, the intracochlear disposition of the electrode array and presence of tip fold over were recorded. Also, eight fresh human temporal bones were studied after insertion in two conditions: correct alignment of the electrode array during the insertion and misaligned...
August 8, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28784015/effects-of-pepsin-a-on-heat-shock-protein-70-response-in-laryngopharyngeal-reflux-patients-with-chronic-rhinosinusitis
#4
Jing Wang, Zhao Yu, Jianjun Ren, Yang Xu, Yuke Zhang, Lei Lei, Yongbo Zheng, Ligao Huang, Zhaoping He
OBJECTIVES: We investigated the relationship between laryngopharyngeal reflux (LPR) and chronic rhinosinusitis (CRS), and explored the effects of pepsin A on the level of heat shock protein 70 (HSP70) in CRS. METHODS: We included 23 CRS patients with nasal polyps (CRSwNP), 26 CRS patients without nasal polyps (CRSsNP) and nine normal controls to measure pepsin A levels in nasal secretions, blood plasma and nasal tissues, to measure HSP70 levels in nasal tissues, and to detect pepsinogen A, HSPA5, cyclo-oxygenase-2 (COX-2), and carbonic anhydrase III (CAIII) mRNA expression levels in nasal tissues...
August 8, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28758555/sequential-motion-of-the-ossicular-chain-measured-by-laser-doppler-vibrometry
#5
Yasuomi Kunimoto, Kensaku Hasegawa, Shiro Arii, Hideyuki Kataoka, Hiroaki Yazama, Junko Kuya, Kazunori Fujiwara, Hiromi Takeuchi
OBJECTIVE: In order to help a surgeon make the best decision, a more objective method of measuring ossicular motion is required. METHODS: A laser Doppler vibrometer was mounted on a surgical microscope. To measure ossicular chain vibrations, eight patients with cochlear implants were investigated. To assess the motions of the ossicular chain, velocities at five points were measured with tonal stimuli of 1 and 3 kHz, which yielded reproducible results. The sequential amplitude change at each point was calculated with phase shifting from the tonal stimulus...
July 31, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28758552/correlation-between-hpv-status-at-t-and-n-sites-of-oropharyngeal-squamous-cell-carcinomas
#6
Michael Vallop Josiassen, Birgitte Charabi, Christel Braemer Lajer, Emilie Garnaes, Marianne Hamilton Therkildsen, Bodil Norrild, Lena Specht, Finn Cilius Nielsen, Christian von Buchwald
OBJECTIVES: Human papilloma virus (HPV) is known to be associated with oropharyngeal squamous cell carcinomas (OPSCC) and may potentially play a vital role in tumor metastasis. The purpose of this study was to correlate HPV status of cervical lymph node metastases with their respective primary OPSCC tumor. METHODS: Formalin-fixed, paraffin-embedded (FFPE) tissue samples obtained from 34 patients with cervical lymph node metastases were analyzed with HPV 16 DNA polymerase chain reaction (PCR), p16 immunohistochemistry and HPV typing...
July 30, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28754079/plunging-ranula-patient-characteristics-treatment-and-comparison-between-different-populations
#7
Annina Lyly, Eeva Castrén, Johanna Aronniemi, Tuomas Klockars
OBJECTIVES: To review our clinical experience and characteristics of Finnish patients with plunging ranula and compare our results with reports from other populations. DESIGN: A retrospective study from the electronic hospital records between 2005 and 2016. SETTING: The Department of Otorhinolaryngology and Head and Neck Surgery of Helsinki University Hospital, Finland. RESULTS: We describe the characteristics and treatment of 41 patients with MRI-confirmed plunging ranula...
July 28, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28754077/treatment-of-the-donor-site-of-free-radial-flaps-vacuum-sealing-versus-conventional-wound-care
#8
Michael Koch, Kavan Jalyzada, Philipp Grundtner, Heinrich Iro, Claudia Scherl, Ulrich Harréus, Julian Künzel
INTRODUCTION: Radial forearm flap donor side defects can be treated by vacuum therapy and conventional wound dressing. The aim of this study was to compare different wound management considering wound healing, including risk factors and cost effectiveness. MATERIALS AND METHODS: Retrospective study including patients treated with radial flaps in the Department of Head and Neck Surgery in Erlangen from January 2005 to August 2013. Wound healing was assessed regarding complications considering several risk factors and comorbidities...
July 28, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28749243/epidemiology-and-trend-of-pediatric-adenoidectomy-a-population-based-study-in-taiwan-from-1997-to-2012
#9
Chia-Hsuan Lee, Wei-Chung Hsu, Jenq-Yuh Ko, Te-Huei Yeh, Wei-Hsiu Chang, Kun-Tai Kang
OBJECTIVES: To assess population-level data for pediatric adenoidectomy. METHODS: Using data from the Taiwan National Health Insurance Research Database for the 1997-2012 period, all inpatients <18 years who received adenoidectomies were identified by codes from the International Classification of Diseases, 9th Revision. RESULTS: A total of 20,599 children underwent adenoidectomy (mean age, 7.4 years; 67% boys). The overall incidence rate was 24...
July 27, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28749204/revision-of-a-furosemide-loading-vestibular-evoked-myogenic-potential-protocol-for-detecting-endolymphatic-hydrops
#10
Toru Seo, Ko Shiraishi, Takaaki Kobayashi, Kitano Mutsukazu, Takeshi Fujita, Kazuya Saito, Katsumi Doi
OBJECTIVE: The presence of endolymphatic hydrops can be suggested by improving the amplitude of vestibular-evoked myogenic potential (VEMP) after furosemide administration (furosemide loading VEMP [FVEMP]). The authors aimed to determine a stimulation frequency and judgment criteria to ascertain whether a revised FVEMP protocol can be applied to clinical settings. METHODS: The study included 25 individuals with unilateral Meniere's disease (MD) and 11 normal healthy volunteers...
July 27, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28749194/results-of-preoperative-chemoradiotherapy-for-patients-with-advanced-cancer-of-the-nasal-cavity-and-paranasal-sinuses
#11
Erik Fernström, Jan Nyman, Eva Hammerlid, Erik Holmberg, Hedda Haugen-Cange, Karin Petruson, Edvard Abel, Thomas Björk-Eriksson
OBJECTIVES: Curative treatment of nasal cavity and paranasal sinus cancer is challenging due to the proximity to critical anatomical structures. The purpose of this study was to analyze the impact of trimodality therapy with preoperative chemotherapy and reduced-dose radiotherapy followed by organ-preserving surgery for treating patients with nasal cavity and paranasal sinus cancer. METHODS: This retrospective study included all 156 patients diagnosed with sinonasal cancer in western Sweden between 1986 and 2009...
July 27, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28743209/endoscopic-surgery-for-early-stage-nasopharyngeal-carcinoma-a-justified-initial-option
#12
Yan Huang, Qian-Hui Qiu
OBJECTIVES: To assess the prognosis of initial endoscopic surgery in T1N0M0 and T2N0M0 staged NPC patients. MATERIALS AND METHODS: Between 2002 and 2016, 10 previously untreated patients with T1N0M0 or T2N0M0 staged NPC volunteered to receive endoscopic surgery followed by four courses of TPF chemotherapy. EORTC QLQ-C30 and QLQ-H&N35 were used to evaluate the QOL after treatment. RESULTS: With the median follow-up of 30 months (range, 9 months to 128 months), the 24-month survival rate was 100% (6/6), 90% (9/10) patients were still alive and well, 20% (2/10) patients reported tumor recurrence...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28743201/pharyngotomy-in-head-and-neck-squamous-cell-carcinoma-functional-and-oncological-aspects
#13
Carolin Remmert, Naglaa Mansour, Benedikt Hofauer, Elias Q Scherer, Murat Bas, Henning Bier, Andreas Knopf
BACKGROUND: Head and Neck Surgery constantly has to oppose non-invasive organ preservation methods and therefore should be evaluated especially with regard to clinical and functional outcome. We will discuss the role of pharyngotomy in the treatment of HNSCC. METHODS: Seventy-three patients with carcinoma of the oral cavity, oro-/hypopharynx and supraglottis underwent lateral/median pharyngotomy. Functional and oncological parameters were retrospectively assessed and set into clinical context...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28741445/results-of-endoscopic-cartilage-tympanoplasty-procedure-with-limited-tympanomeatal-flap-incision
#14
Isa Kaya, Goksel Turhal, Arin Ozturk, Sercan Gode, Cem Bilgen, Tayfun Kirazli
OBJECTIVE: The aim of this study was to evaluate the outcomes of this minimally invasive tympanomeatal incision technique performed during endoscopic transcanal cartilage tympanoplasty. STUDY DESIGN: Prospective clinical study. METHODS: Eighty-seven patients (87 ears) who had TM perforation with noncomplicated COM were included. All of the patients were operated with the endoscopic transcanal cartilage tympanoplasty technique. All of the data were prospectively collected...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28741444/mild-pulmonary-emphysema-a-risk-factor-for-interstitial-lung-disease-when-using-cetuximab-for-squamous-cell-carcinoma-of-the-head-and-neck
#15
Isaku Okamoto, Kiyoaki Tsukahara, Hiroki Sato, Ray Motohashi, Daisuke Yunaiyama, Akira Shimizu
BACKGROUND: Interstitial lung disease (ILD) is an occasionally fatal adverse event associated with cetuximab (Cmab) therapy. Our objective was to clarify to what degree pulmonary emphysema is a risk factor in the treatment of head and neck cancer with Cmab through a retrospective analysis. METHODS: Subjects were 116 patients who were administered Cmab for head and neck squamous cell carcinoma. The degree of pulmonary emphysema before initiating treatment with Cmab was visually assessed retrospectively, with scoring according to the Goddard classification used in Japanese chronic obstructive pulmonary disease (COPD) guidelines for chest computed tomography (CT)...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28741409/foxp3-expression-in-lymph-node-metastases-in-patients-with-head-and-neck-cancer
#16
Mehtap Boduc, Marion Roessler, Robert Mandic, Christoph Netzer, Christian Güldner, Ute Walliczek-Dworschak, Boris A Stuck, Magis Mandapathil
INTRODUCTION: The prevalence and activity of regulatory T cells in patients with cancer correlates with poor prognosis. These cells are characterized by their expression of Forkhead box protein-3 (Foxp3). Squamous cell carcinoma is the most prevalent type of cancer in the head and neck region with overall poor survival rates, also due to early spread of metastatic cells. MATERIAL AND METHODS: Primary tumor specimens as well as lymph node specimens harvested during neck dissection of 65 patients with a diagnosis of HNSCC were subjected to immunohistochemical and H-score analysis of Foxp3 expression...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28741406/balanced-endoscopic-medial-and-transcutaneous-lateral-orbital-decompression-in-graves-orbitopathy
#17
Estefanía Hernández-García, J Javier San-Román, Ramón González, Araceli Nogueira, Ignacio Genol, Bazil Stoica, Nicolás Toledano, Guillermo Plaza
BACKGROUND: To determine the clinical outcomes and morbidity of endoscopic medial wall combined with transcutaneous lateral orbital wall decompression in Graves' orbitopathy. METHODOLOGY: A retrospective noncomparative case series of patients who underwent surgical decompression for Graves' orbitopathy at Hospital Universitario de Fuenlabrada between 2004 and 2014 was performed. We reviewed the patients' charts and analyzed before and after the decompression, the visual acuity (Snellen chart), optic nerve compression (fundoscopy and optic coherence tomography), exophthalmometry (Hertel measurement), ocular motility, diplopia, eyelid surgery needed after decompression and its possible complications...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28741403/comparative-study-between-the-caloric-vestibular-and-the-video-head-impulse-tests-in-unilateral-meni%C3%A3-re-s-disease
#18
Jonathan Andrés Cordero-Yanza, Edna Verónica Arrieta Vázquez, Juan Carlos Hernaiz Leonardo, Jimena Mancera Sánchez, Mario Sabas Hernández Palestina, Nicolás Pérez-Fernández
OBJECTIVE: Compare the caloric vestibular test (CVT) and the video head impulse test (vHIT) in the evaluation of Meniere's disease (MD) and to analyze their diagnostic accuracy. MATERIALS AND METHODS: Retrospective review of CVT and vHIT performed in MD patients at a tertiary care referral center in Spain. RESULTS: A total of 88 patients were reviewed. The CVT was abnormal in 67% (n = 59) of patients, while the vHIT was abnormal in 66% (n = 58) of them...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28741402/bipolar-dissection-technique-in-parotid-gland-surgery
#19
Andreas Knopf, Clemens Heiser, Özlem Karasoy, Benedikt Hofauer, Henning Bier, Naglaa Mansour
BACKGROUND: Parotid gland surgery (PGS) has to manage the balancing act between sufficient radicality and preservation of functional structures. While many studies evaluate post-therapeutic complication due to different extent of surgery, the current study introduces bipolar dissection (BP) being a fast and safe preparation technique. METHODS: Analysis of clinical parameters (age, sex, tumour entity, treatment modalities, facial nerve palsy, bleeding, saliva fistula and Frey's syndrome) of 319 consecutively included patients who underwent extracapsular dissection and superficial/total/radical parotidectomy...
July 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28741396/intraoperative-nerve-monitoring-reduces-recurrent-laryngeal-nerve-injury-in-geriatric-patients-undergoing-thyroid-surgery
#20
Huang Kai, Lin Xixia, Long Miaoyun, Chen Qinchang, Peng Xinzhi, Luo Dingyuan, Li Honghao
OBJECTIVE: This research was aimed to investigate whether the intraoperative nerve monitoring (IONM) can reduce the incidence of recurrent laryngeal nerve (RLN) injury in geriatric patients undergoing thyroid surgery. METHODS: This retrospective cohort study included 522 geriatric patients undergoing thyroid surgery between January 2013 and June 2016 in the Sun Yat-sen Memorial Hospital. Patients with IONM during the surgery (n = 340) were compared with patients without IONM (n = 212)...
July 25, 2017: Acta Oto-laryngologica
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