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Acta Obstetricia et Gynecologica Scandinavica

Cassandra R Duffy, Janet L Moore, Sarah Saleem, Antoinette Tshefu, Carl L Bose, Elwyn Chomba, Waldemar A Carlo, Ana L Garces, Nancy F Krebs, K Michael Hambidge, Shivaprasad S Goudar, Richard J Derman, Archana Patel, Patricia L Hibberd, Fabian Esamai, Edward A Liechty, Dennis D Wallace, Elizabeth M McClure, Robert L Goldenberg
INTRODUCTION: Uncertainty exists regarding the impact of malpresentation on pregnancy outcomes and the optimal mode of delivery in low- and middle-income countries. We sought to compare outcomes between cephalic and non-cephalic pregnancies. MATERIAL AND METHODS: Using the NICHD Global Network's prospective, population-based registry of pregnancy outcomes from 2010-2016, we studied outcomes in 436,112 singleton pregnancies. Robust Poisson regressions were used to estimate the risk of adverse outcomes associated with malpresentation...
November 10, 2018: Acta Obstetricia et Gynecologica Scandinavica
Shigeki Matsubara
A larger surgical volume leads to better surgical outcomes, which holds true to surgery for placenta accreta spectrum (PAS) disorders. PAS patients should be managed at specialized centers. However, Sargent and Collins demonstrated that this was not the case in England; 63% of non-specialist centers perform PAS surgery without referring them to specialist centers. They stated that "the benefit of referral to more experienced centers may not be understood", but not understood by whom, doctors, patients, or societies, needs some clarification...
November 9, 2018: Acta Obstetricia et Gynecologica Scandinavica
Anne Kaasen, Kristin Jerve Aanstad, Aase Serine Devold Pay, Inger Økland, Ellen Blix
INTRODUCTION: This study describes clinical routines for intrapartum fetal monitoring in Norway and compliance with national clinical recommendations. MATERIAL AND METHODS: A national survey of all (n = 48) birth units in Norway, using a self-reporting questionnaire about fetal monitoring methods and devices available in the birth units, admission cardiotocography (CTG) use, intrapartum fetal monitoring methods for women with and without risk factors, the availability of fetal scalp blood sampling facilities, and umbilical cord blood sampling routines...
October 30, 2018: Acta Obstetricia et Gynecologica Scandinavica
Amir Aviram, Christopher Sherman, John Kingdom, Arthur Zaltz, Jon Barrett, Nir Melamed
INTRODUCTION: While early and late fetal growth restriction have been suggested to be distinct entities, the optimal gestational age cut-off that differentiates the two conditions is currently unclear and has been arbitrarily set in previous studies between 32 and 37 weeks. We aimed to use placental pathology findings to determine that optimal gestational age cut-off between early and late fetal growth restriction. MATERIAL AND METHODS: A retrospective cohort study of all women with singleton gestation who gave birth to a neonate diagnosed as small-for-gestational age (small-for-gestational age, defined as birth weight<10th percentile for gestational age) at a tertiary referral center between January 2001 and December 2015, and for whom placental pathology was available...
October 29, 2018: Acta Obstetricia et Gynecologica Scandinavica
Will Sargent, Sally L Collins
INTRODUCTION: The aim of this study was to investigate the planned place of delivery for women antenatally diagnosed with abnormally invasive placenta (AIP) in England and identify how many units regard themselves to be 'specialist centres' for the management of AIP. MATERIAL AND METHODS: Observational study of obstetric-led units in England. An anonymous survey sent to the delivery suite lead clinician in all 154 consultant-led units throughout England. The main outcome measures were whether each unit planned to manage AIP 'in-house', estimated number of AIP cases delivered in the previous five years and whether they considered themselves a 'specialist centre' for AIP management...
October 28, 2018: Acta Obstetricia et Gynecologica Scandinavica
Akiko Yamaguchi, Hyo Kyozuka, Keiya Fujimori, Mitsuaki Hosoya, Seiji Yasumura, Tadahiko Yokoyama, Akiko Sato, Koichi Hashimoto
INTRODUCTION: This study evaluated the risk of preterm birth, low birthweight, and small-for-gestational-age neonates born to mothers with adenomyosis during pregnancy. MATERIAL AND METHODS: We used the results of a Japanese nationwide prospective birth cohort study, identifying 93 668 singleton deliveries from 2011 to 2014. We identified 314 pregnancies with adenomyosis using self-reported questionnaires. Multiple logistic regression analyses were conducted to examine whether adenomyosis was associated with adverse pregnancy outcome...
October 26, 2018: Acta Obstetricia et Gynecologica Scandinavica
Rüdiger Klapdor, Peter Hillemanns
Rodríguez-Trujillo et al. present a very interesting retrospective study on inguinal lymphadenectomy (IFL) vs sentinel lymph node dissection (SLN) in vulvar cancer. Several studies have been published analyzing this topic. However, a prospective randomized study is still missing. Although SLN leads to lower morbidity, there are still concerns, whether SLN is as safe as IFL regarding groin recurrences and mortality. The GROINSS-V study encouraged all gynecologists to perform SLN by reaching excellent low recurrent rates (6/253, 2...
October 26, 2018: Acta Obstetricia et Gynecologica Scandinavica
Timme P Schaap, Thomas van den Akker, Joost J Zwart, Jos van Roosmalen, Kitty W M Bloemenkamp
INTRODUCTION: There have been many efforts in the last decade to decrease the incidence of eclampsia and its related complications in the Netherlands, such as lowering thresholds for treatment of hypertension and mandatory professional training. In order to determine the impact of these policy changes on incidence and outcomes, we performed a nationwide registration of eclampsia, ten years after the previous registration. MATERIAL AND METHODS: Cases of eclampsia were prospectively collected using the Netherlands Obstetric Surveillance System (NethOSS; 2013-2016) in all hospitals with a maternity unit in the Netherlands...
October 22, 2018: Acta Obstetricia et Gynecologica Scandinavica
Maria Katsogiannou, Xavier-Côme Donato, Anderson Loundou, Eric Glowaczower, Marie Raffray, Brigitte Planchet-Barraud, Edwin Quarello, Marie-Pierre Brechard, Raoul Desbriere
INTRODUCTION: Transabdominal chorionic villus sampling (CVS) is an invasive procedure for prenatal diagnosis reported to be associated with anxiety and pain. In this context, the need for analgesia during CVS has been considered useful. Even though several authors have been interested in pain management during amniocentesis, no study has been published on pain reduction during CVS. Our objective was to evaluate pain and anxiety management during transabdominal CVS using nitrous oxide (N2 O) and local anesthesia...
October 22, 2018: Acta Obstetricia et Gynecologica Scandinavica
Vilma Johnsson, Roger Smith, Line Rode
This is a reply to the comment by Levin & Rottenstreich (1) on our recently published study Plasma progesterone, estradiol, and unconjugated estriol concentrations in twin pregnancies: Relation to cervical length and preterm delivery (2). We would like to thank the authors for showing interest in our research. Our study examined the association between plasma hormone concentrations, cervical length and preterm delivery in twin pregnancies. We also investigated the effect of vaginal progesterone treatment on plasma hormone concentrations...
October 22, 2018: Acta Obstetricia et Gynecologica Scandinavica
Abdullah H Baqui, Anne Cc Lee, Alain K Koffi, Rasheda Khanam, Dipak K Mitra, Sushil Kanta Dasgupta, Jamal Uddin, Parvez Ahmed, Iftekhar Rafiqullah, Mahmoodur Rahman, Abdul Quaiyum, Emilia H Koumans, Parul Christian, Samir K Saha, Luke C Mullany, Alain Labrique
INTRODUCTION: The role of screening and treatment for abnormal vaginal flora (AVF) on adverse pregnancy outcomes remains unclear. Using data from women who participated in a population-based cluster randomized trial who were screened and treated for AVF, we report risk factors for AVF and association of persistent AVF with adverse perinatal outcomes. MATERIAL AND METHODS: Pregnant women (n=4,221) <19 weeks of gestation provided self-administered mid-vaginal swabs; smears were Nugent scored...
October 22, 2018: Acta Obstetricia et Gynecologica Scandinavica
Emre Karasahin
In an interesting article recently published in AOGS (1), Wagner et al conclude that "women with a history of recurrent miscarriage differ in cardiovascular risk profile at a young age compared with women with no miscarriage". While their study incorporated plenty of data, the demographic representation of the data has not been included. The number of recurrent miscarriages has not been mentioned in the paper. This article is protected by copyright. All rights reserved.
October 20, 2018: Acta Obstetricia et Gynecologica Scandinavica
Ahizechukwu C Eke, Jeanne Sheffield, Ernest M Graham
INTRODUCTION: To evaluate whether there are additional benefits of 17-hydroxyprogesterone caproate (17-OHPC) supplementation in preventing recurrent spontaneous preterm birth in women with a prophylactic cerclage. MATERIAL AND METHODS: Electronic databases (MEDLINE, Scopus, ClinicalTrials gov, PROSPERO, EMBASE, Scielo and the Cochrane Central Register of Controlled Trials) were searched for studies published before June 2018. Keywords included "preterm birth," "prophylactic cerclage," "history-indicated cerclage," "pregnancy" and "17-hydroxyprogesterone caproate...
October 19, 2018: Acta Obstetricia et Gynecologica Scandinavica
Victoria Eley, Renuka Sekar, Adrian Chin, Timothy Donovan, Amy Krepska, Mitchell Lawrence, Sheridan Bell, Shaun McGrath, Alexander Robinson, Lachlan Webb, Louise Marquart
INTRODUCTION: Early pregnancy body mass index (BMI) is known to predict adverse pregnancy outcomes but does not account for body fat distribution. This study aimed to prospectively determine if maternal abdominal subcutaneous fat thickness (SCFT) measured by ultrasound at the fetal morphology scan is a better predictor of mode of delivery and other pregnancy outcomes, than BMI. MATERIAL AND METHODS: This was a prospective cohort study of women delivering singleton neonates at a tertiary public hospital...
October 18, 2018: Acta Obstetricia et Gynecologica Scandinavica
Maria Forslund, Kerstin Landin-Wilhelmsen, Johanna Schmidt, Mats Brännström, Penelope Trimpou, Eva Dahlgren
INTRODUCTION: To address the question of whether women with polycystic ovary syndrome (PCOS) reach the menopause later than age-matched controls, we conducted a follow-up cohort study of women with well-characterized PCOS that was diagnosed 24 years ago. The hypothesis was that women with PCOS would reach the menopause later than non-PCOS women. Parity during these 24 years was also studied. MATERIAL AND METHODS: Twenty-seven women, diagnosed with PCOS in 1992 (mean age 29...
October 18, 2018: Acta Obstetricia et Gynecologica Scandinavica
Sakthivignesh Ponandai-Srinivasan, Parameswaran G Lalitkumar, Laura Garcia, Suby Jo Varghese, Joseph W Carlson, Kristina Gemzell-Danielsson, Angelique Floter Radestad
INTRODUCTION: Women with hereditary mutation in breast cancer associated genes (BRCA1-/2- ) have higher lifetime risk for developing ovarian cancer. Here, we aimed to investigate the effect of mifepristone, a selective progesterone receptor modulator on ovarian mesenchymal stem/stromal cells (MSC) from BRCA1-/2- carriers. MATERIAL AND METHODS: Ovarian BRCA1-/2- MSC were positively selected using markers CD90, CD73 and CD105 from nine healthy women. Effect of dose response and combination treatment with mifepristone and analogues of progesterone- or glucocorticoid- receptors were investigated on BRCA1-/2- MSC in vitro using panel of markers for proliferation (ki67, BrdU, CDK2, p21CIP ), apoptosis (BAX, BCL2, CASPASE3), tumor suppression (TP53, PTEN) and cell survival (PI3KCA, MAPK3,mTOR)...
October 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
Christina Kjaergaard Rasmussen, Estrid Staehr Hansen, Margit Dueholm
INTRODUCTION: Our aim was to correlate junctional zone thickness and irregularity (junctional zone disease) and other ultrasonographic features of adenomyosis to histopathology of the endometrial-myometrial junctional zone. MATERIAL AND METHODS: Consecutively enrolled premenopausal women (n=110) scheduled for hysterectomy or transcervical endometrial resection due to abnormal uterine bleeding and/or menstrual pain, underwent two- and three-dimensional transvaginal ultrasonography on the day of surgery blinded to previous diagnosis...
October 14, 2018: Acta Obstetricia et Gynecologica Scandinavica
Gabriel Levin, Amihai Rottenstreich
No abstract text is available yet for this article.
October 14, 2018: Acta Obstetricia et Gynecologica Scandinavica
Xiu-Li Yang, Fei Chen, Xiu-Ying Yang, Guan-Hua Du, Yang Xu
No abstract text is available yet for this article.
October 14, 2018: Acta Obstetricia et Gynecologica Scandinavica
Endah Rahmawati, Wei-Chung Vivian Yang, Yen-Ping Lei, Pawan Kumar Maurya, Huei-Wen Chen, Chii-Ruey Tzeng
INTRODUCTION: Many cell-migration-related molecules are associated with endometriosis. Tensin 1 (TNS1), which has been implicated in cell migration, may play a role in endometriosis. The study goal was to evaluate the TNS1 expression in endometrial tissue and serum from women with endometriosis treated with gonadotropin-releasing hormone agonist (GnRHa). MATERIAL AND METHODS: Tissue and serum samples were collected from women with endometriosis who were treated (n = 29) with GnRHa or untreated (n = 30)...
October 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
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