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Acta Obstetricia et Gynecologica Scandinavica

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https://www.readbyqxmd.com/read/29786834/assessment-of-lactate-production-as-a-response-to-sustained-intrapartum-hypoxia-in-large-for-gestational-age-newborns
#1
Mehreen Zaigham, Karin Källén, Per Olofsson
INTRODUCTION: Lactate concentration in umbilical cord blood is an important measure of intrapartum anaerobic metabolism. The aim of the study was to compare lactate production of large-for-gestational-age (LGA) fetuses against appropriate-for-gestational-age (AGA) fetuses during hypoxia, in diabetic and non-diabetic mothers. MATERIAL AND METHODS: 17 358 validated paired arterial and venous umbilical cord blood samples taken at birth with a full panel of pH, glucose and lactate were analyzed relative to LGA (n=2789) and AGA (n=14 569)...
May 22, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29786833/assessment-of-cerebral-perfusion-and-edema-in-preeclampsia-with-intravoxel-incoherent-motion-mri
#2
Maria Nelander, Daniel Hannsberger, Inger Sundström-Poromaa, Lina Bergman, Jan Weis, Helena Åkerud, Johan Wikström, Anna-Karin Wikström
INTRODUCTION: Cerebral complications are the main reasons for morbidity and mortality in preeclampsia and eclampsia. Still we do not know if the pathophysiology entails hypo- or hyperperfusion of the brain, or how and when edema emerges, due to the difficulty to examine the cerebral circulation. MATERIAL AND METHODS: We have used a non-invasive diffusion weighted magnetic resonance imaging (MRI) technique, intravoxel incoherent motion, to study cerebral perfusion on the capillary level and cerebral edema in women with preeclampsia (n=30), normal pregnancy (n=32) and non-pregnant women (n=16)...
May 22, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29782643/lifetime-number-of-years-of-menstruation-as-a-risk-index-for-postmenopausal-endometrial-cancer-in-the-norwegian-women-and-cancer-study
#3
Oxana Gavrilyuk, Tonje Braaten, Elisabete Weiderpass, Idlir Licaj, Eiliv Lund
INTRODUCTION: Lifetime number of years of menstruation (LNYM) reflects a woman's cumulative exposure to endogenous estrogen and can be used as a measure of the combined effect of reproductive factors related to endometrial cancer (EC) risk. MATERIAL AND METHODS: We aimed to study the association between LNYM and EC risk among postmenopausal women and calculate the population attributable fraction of EC for different LNYM categories. Our study sample consisted of 117 589 women from the Norwegian Women and Cancer (NOWAC) Study...
May 21, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29777635/reducing-the-number-of-obstetrical-beds-by-challenging-traditions
#4
Camilla Dalby Salvig, Marie Højriis Storkholm, Jannie Dalby Salvig, Niels Uldbjerg
The aim of this commentary is to describe changes in women care at an obstetric department that made it possible to reduce the number of beds from 40 to 29. Patient pathways were reviewed and revised using lean methodology. The mean length of stay was reduced from 70 to 59 hours and the mean numbers of hospitalizations per woman from 1.26 to 1.20. At the organizational level, we introduced a Family Department, home management of newborns, home monitoring of the women with cardiotocography and blood samples, and intrapartum Group B Streptococcus-PCR...
May 19, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29772119/hysterectomy-route-and-readmissions-a-reply
#5
Jon Ivar Einarsson
We thank the author for his thoughtful comments (1) and for pointing out some inherent flaws with retrospective studies. We made every attempt to present a balanced view (2), but there are data that are not captured in the database that we are using, including the ones that the author mentions. However, given the size of the sample, it seems likely that at least some of these variables were evenly distributed. This article is protected by copyright. All rights reserved.
May 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29772076/victims-and-victimisation
#6
Matthew Cauldwell, Susan Bewley
We congratulate McNamara et al. on their work examining the impact that intrapartum stillbirth has on obstetricians (1). The findings from their qualitative study highlight and reinforce themes others have identified. We conducted a similar study interviewing maternity staff (consultant obstetricians, trainees and midwives) about the impact of their involvement in rarer maternal death cases (2). We reported similar themes particularly around the fear of blame. This was perceived as coming not only from the media but also from professional colleagues...
May 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29772056/maternal-plasma-leptin-levels-in-relation-to-the-duration-of-the-active-phase-of-labor
#7
Sara Carlhäll, Karin Källén, Annika Thorsell, Marie Blomberg
INTRODUCTION: Obese women have increased leptin levels and longer duration of labor compared to normal weight women. Leptin has an inhibitory effect on myometrial contractility in vitro. Our purpose was to examine whether maternal leptin levels in active labor were associated with the duration of the active phase of labor. MATERIAL AND METHODS: This prospective cohort study included 914 women. Maternal blood samples were collected in active labor. The plasma-leptin concentration was obtained using a direct sandwich-based ELISA...
May 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29772055/the-role-of-procalcitonin-in-the-diagnosis-and-management-of-infections-in-the-field-of-obstetrics-and-gynecology
#8
Gabriel Levin, Amihai Rottenstreich
We read the editorial by Tujula et al. with great interest (1). They described the role of procalcitonin as biomarker for the diagnosis of infection and monitoring of antibiotic treatment. Despite their meticulous citation data collection, several important issues need further consideration.In their report, the authors have claimed that 'proclacitonin seems to be a useful biomarker for severe bacterial infections and this is likely to be the case also in Obstetrics and Gynecology'. This article is protected by copyright...
May 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29772054/oxycodone-pharmacokinetics-and-fetal-exposure-after-intravenous-or-epidural-administration-to-the-ewe
#9
Mari Kinnunen, Hannu Kokki, Heidi Hautajärvi, Heikki Huhta, Veli-Pekka Ranta, Juha Räsänen, Hanna-Marja Voipio, Merja Kokki
INTRODUCTION: There are limited data of oxycodone pharmacokinetics during pregnancy and on fetal exposure after maternal administration. The present study describes the pharmacokinetics of intravenous oxycodone in pregnant sheep and fetal exposure after intravenous and epidural administration. MATERIAL AND METHODS: 10 pregnant sheep received 0.1 mg·kg-1 oxycodone intravenously -bolus, and blood samples were collected up to 24 hours. Seven days later, the ewes were randomized to receive 0...
May 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29772053/delivery-outcome-after-trial-of-labor-in-nulliparous-women-over-40-years-of-age-a-population-based-study
#10
Victoria Ankarcrona, Daniel Altman, Anna-Karin Wikström, Bo Jacobsson, Sophia Brismar Wendel
INTRODUCTION: An increasing proportion of nulliparous women are over 40 years and labor is more often induced. The aim of this study was to assess delivery outcome in women over 40 years, accounting for the interaction between age and induction. MATERIAL AND METHODS: Population-based study of 1 644 598 nulliparous women with live singleton cephalic term deliveries 1992 to 2011. Risks of intrapartum cesarean section, operative vaginal delivery, obstetric anal sphincter injury (OASIS), and 5-minutes Apgar score <7 were calculated in women ≥40 years with induced or spontaneous labor, and women <40 years with induced labor by unconditional logistic regression, and presented with crude and adjusted odds ratios (aOR) with 95% confidence intervals (95%CI)...
May 17, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29770435/fetal-rotation-during-vacuum-extractions-for-prolonged-labour-a-prospective-cohort-study
#11
Birgitte Heiberg Kahrs, Sana Usman, Tullio Ghi, Aly Youssef, Erik Andreas Torkildsen, Elsa Lindtjørn, Tilde Borch Østborg, Sigurlaug Benediktsdottir, Lis Brooks, Lotte Harmsen, Kjell Åsmund Salvesen, Cristoph C Lees, Torbjørn Moe Eggebø
INTRODUCTION: The aim of the study was to investigate fetal head rotation during vacuum extraction. MATERIAL AND METHODS: We conducted a prospective cohort study from November 2013 to July 2016 in seven European hospitals. Fetal head position was determined with transabdominal or transperineal ultrasound and categorized as occiput anterior (OA), occiput transverse (OT) or occiput posterior (OP) position. Main outcome was the proportion of fetuses rotating during vacuum extraction...
May 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29768660/validation-of-a-computerized-algorithm-to-quantify-fetal-heart-rate-deceleration-area
#12
Erika Gyllencreutz, Ke Lu, Kaj Lindecrantz, Pelle G Lindqvist, Lennart Nordstrom, Malin Holzmann, Farhad Abtahi
INTRODUCTION: Reliability in visual cardiotocography interpretation is unsatisfying, which has led to development of computerized cardiotocography. Computerized analysis is well established for antenatal fetal surveillance, but has yet not performed sufficiently during labor. We aimed to investigate the capacity of a new computerized algorithm compared to visual assessment in identifying intrapartum fetal heart rate baseline and decelerations. MATERIAL AND METHODS: Three-hundred-and-twelve intrapartum cardiotocography tracings with variable decelerations were analysed by the computerized algorithm and visually examined by two observers, blinded to each other and the computer analysis...
May 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29768659/influence-of-pregnancy-on-cardiac-function-and-hemodynamics-in-women-with-ebstein-s-anomaly
#13
Miki Kanoh, Kei Inai, Tokuko Shinohara, Eriko Shimada, Mikiko Shimizu, Hirofumi Tomimatsu, Masaki Ogawa, Toshio Nakanishi
INTRODUCTION: We examined the perinatal outcomes and right ventricular function before pregnancy, during pregnancy, and after delivery in women with Ebstein's anomaly. MATERIAL AND METHODS: We retrospectively investigated the clinical course and mode of delivery and monitored hemodynamic parameters throughout pregnancy in 17 women with Ebstein's anomaly, who delivered at our institution during the period of 1995-2015. RESULTS: Eight women, including nine pregnancies, underwent elective cesarean section, and nine women, including 14 pregnancies, underwent vaginal delivery...
May 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29768650/gestation-at-birth-mode-of-birth-infant-feeding-and-childhood-hospitalization-with-infection
#14
Jason P Bentley, David P Burgner, Antonia W Shand, Jane C Bell, Jessica E Miller, Natasha Nassar
INTRODUCTION: Infections are a leading cause of mortality and morbidity in preschool children. We aimed to assess the impact of the co-occurrence of cesarean section, early birth and formula feeding on hospitalization with infection in early childhood. MATERIAL AND METHODS: Population-based retrospective record-linkage cohort study of 488 603 singleton livebirths ≥32 weeks gestational age in New South Wales, Australia, 2007-2012. Multivariable Cox-regression was used to estimate independent and combined adjusted associations of gestational age, mode of birth (vaginal or cesarean section by labor onset) and formula feeding with time to first and repeat hospitalization with infection for children <5 years of age...
May 16, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29754435/questionnaire-based-evaluation-of-sexual-life-after-laparoscopic-surgery-for-endometriosis-a-systematic-review-of-prospective-studies
#15
Cecilie Franck, Marlene Højhus Poulsen, Grigorios Karampas, Annamaria Giraldi, Martin Rudnicki
INTRODUCTION: Endometriosis is a benign disease, which affects women of reproductive age. Laparoscopic excision of endometriotic implants is considered one of the most effective therapeutic options. The disease and its treatment can have major impact on psychosexual well-being but this is often overlooked as most studies focus on pain instead of sexuality in a holistic approach. The aim of this study was to review the current literature regarding the effect of laparoscopic surgery for endometriosis on quality of sexual life (QoSL)...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29754409/comparison-of-transvaginal-ultrasound-and-saline-contrast-sonohysterography-in-evaluation-of-cesarean-scar-defect-a-prospective-cohort-study
#16
Riitta Antila-Långsjö, Johanna U Mäenpää, Heini Huhtala, Eija Tomás, Synnöve Staff
INTRODUCTION: The aim of this study was to investigate the prevalence of post-cesarean isthmocele and to measure agreement between transvaginal ultrasonography and saline contrast sonohysterography in assessment of isthmocele. MATERIAL AND METHODS: Prospective observational cohort study was carried out at Tampere University Hospital, Finland. Non-pregnant women delivered by cesarean section (n=371) were examined with transvaginal ultrasonography (TVUS) and sonohysterography (SHG) six months after cesarean section...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29754393/predicting-stress-urinary-incontinence-during-pregnancy-combination-of-pelvic-floor-ultrasound-parameters-and-clinical-factors
#17
Ling Chen, Dan Luo, Xiajuan Yu, Mei Jin, Wenzhi Cai
INTRODUCTION: The aim of this study was to develop and validate a predictive tool that combining pelvic floor ultrasound parameters and clinical factors for stress urinary incontinence during pregnancy. MATERIAL AND METHODS: A total of 535 women in first or second trimester were included for an interview and transperineal ultrasound assessment from two hospitals. Imaging data sets were analyzed offline to assess for bladder neck vertical position, urethra angles (α, β, and γ angles), hiatal area and bladder neck funneling...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29753309/endometriosis-and-adenomyosis-are-associated-with-increased-risk-of-preterm-delivery-and-a-small-for-gestational-age-child-a-systematic-review-and-meta-analysis
#18
Mette Rahbek Bruun, Linn Håkonsen Arendt, Axel Forman, Cecilia Høst Ramlau-Hansen
INTRODUCTION: The objective of this systematic review and meta-analysis was to evaluate the risk of preterm delivery and having a small for gestational age child in women with endometriosis and adenomyosis compared to women without these two diseases. MATERIAL AND METHODS: Studies on endometriosis or adenomyosis and risk of preterm delivery and/or small for gestational age were included. The systematic search was conducted for all published articles in PubMed and Embase published from 1950 to 2017 using specific search terms...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29753307/antenatal-risk-factors-associated-with-neonatal-morbidity-in-large-for-gestational-age-infants-an-international-prospective-cohort-study
#19
Matias C Vieira, Lesley Me McCowan, Robyn A North, Jenny E Myers, James J Walker, Philip N Baker, Gustaaf A Dekker, Louise C Kenny, Lucilla Poston, Dharmintra Pasupathy
INTRODUCTION: Large for gestational age (LGA) infants are associated with increased risk of neonatal morbidity and mortality, however most of them will not have adverse outcomes. Our aim was to identify antenatal clinical factors associated with neonatal morbidity in LGA infants. MATERIAL AND METHODS: Nulliparous women from the Screening for Pregnancy Endpoints (SCOPE) study were included. We compared maternal and fetal factors between LGA infants (birthweight >90th customized centile) with and without neonatal morbidity, defined as admission to neonatal intensive care unit or severe neonatal morbidity...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29752811/confounding-factors-on-the-association-between-hysterectomy-route-and-readmissions
#20
Mark C Kendall
I read with great interest the article by Kreuninger et al. in a recent issue of the journal (1). The authors performed a retrospective study on 3,981 hysterectomy cases and concluded that the laparoscopic approach to hysterectomy was associated with fewer hospital readmissions compared with the abdominal route. Moreover; the vaginal, robotic and abdominal approaches to hysterectomy demonstrated similar risks of readmission. This article is protected by copyright. All rights reserved.
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
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