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Acta Dermato-venereologica

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https://www.readbyqxmd.com/read/29437191/yellow-brown-papules-on-the-cheeks-and-limbs-of-a-male-infant-a-quiz
#1
Julia K Winkler, Susanne Hanner, Arno Rütten, Alexander H Enk, Holger Hänßle, Ferdinand Toberer
No abstract text is available yet for this article.
February 13, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29437190/8-methoxypsoralen-plus-ultraviolet-a-reduces-the-susceptibility-of-murine-skin-to-mount-a-psoriatic-response-to-imiquimod-linked-with-senescence-and-downregulation-of-interleukin-9-17-and-interferon-gamma
#2
Nitesh Shirsath, Karin Wagner, Simone Roos, Michaela Schlederer, Christian Ringel, Lukas Kenner, Bernhard Brüne, Peter Wolf
The effects of 8-methoxypsoralen plus ultraviolet A (PUVA) and ultraviolet B (UVB) on imiquimod-induced psoriasis were examined in a mouse model. Mouse skin was treated with repetitive sub-phototoxic doses of PUVA or UVB before or during the induction of toll-like receptor 7/8 activation and psoriasis through the application of imiquimod. PUVA, to a greater degree than UVB, suppressed the established imiquimod-induced psoriatic phenotype, but pretreatment with PUVA prior to administration of imiquimod also reduced the susceptibility of murine skin to respond to imiquimod to a greater degree than did UVB...
February 13, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29437189/aquagenic-pruritus-in-polycythemia-vera-clinical-characteristics
#3
Edyta Lelonek, Łukasz Matusiak, Tomasz Wróbel, Jacek C Szepietowski
Aquagenic pruritus is one of the main clinical features of polycythemia vera. The aim of this study was to analyse the clinical characteristics of aquagenic pruritus. The study group comprised 102 patients with molecularly confirmed polycythemia vera. Demographic data, data on disease history, polycythemia vera status and treatment modalities were collected. Moreover, various clinical features of aquagenic pruritus (including intensity, localization, quality, descriptors) and the most common factors responsible for its aggravation or alleviation were examined...
February 13, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29437188/folate-supplementation-during-methotrexate-therapy-a-population-based-retrospective-cohort-study
#4
Canelle Mazaud, Laurence Fardet
No abstract text is available yet for this article.
February 13, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29437187/generalized-chronic-itch-as-a-first-sign-of-malignancy-resembling-paraneoplastic-sensomotoric-neuropathy
#5
Minaya Beigi, Michael Häberle, Andreas Gschwendtner, Ulrich Baum, Elke Weisshaar
No abstract text is available yet for this article.
February 13, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29437186/evaluation-of-igg4-plasma-cell-infiltration-in-patients-with-systemic-plasmacytosis-and-other-plasma-cell-infiltrating-skin-diseases
#6
Shintaro Takeoka, Masahiro Kamata, Carren Sy Hau, Mihoko Tateishi, Saki Fukaya, Kotaro Hayashi, Atsuko Fukuyasu, Takamitsu Tanaka, Takeko Ishikawa, Takamitsu Ohnishi, Yuko Sasajima, Shinichi Watanabe, Yayoi Tada
Systemic plasmacytosis is a rare skin disorder characterized by marked infiltration of plasma cells in the dermis. IgG4-related disease is pathologically characterized by lymphoplasmacytic infiltration rich in IgG4+ plasma cells, storiform fibrosis, and obliterative phlebitis, accompanied by elevated levels of serum IgG4. Reports of cases of systemic plasmacytosis with abundant infiltration of IgG4+ plasma cells has led to discussion about the relationship between systemic plasmacytosis and IgG4-related disease...
February 13, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29405248/rasa1-variants-in-capillary-malformations-of-children-a-comment-to-maruani-a-et-al
#7
Rudolf Happle
No abstract text is available yet for this article.
February 6, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29405247/brownish-plaque-with-progressive-growth-on-the-breast-a-quiz
#8
Javier Arellano, Maria Jose Mesa, Yamile Corredoira
No abstract text is available yet for this article.
February 6, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29405246/metastasis-risk-of-cutaneous-squamous-cell-carcinoma-in-organ-transplant-recipients-and-immunocompetent-patients
#9
Roel E Genders, Joris A J Osinga, Elise E Tromp, Peter O'Rourke, Jan N Bouwes Bavinck, Elsemieke I Plasmeijer
Organ transplant recipients (OTRs) have a high incidence of cutaneous squamous cell carcinoma (cSCC), and immunosuppression has been reported to be an important risk factor for metastasis. The aim of this study was to identify the metastasis risk over a 10-year period for 593 patients with cSCC, of whom 134 were OTR and 459 were immunocompetent. Metastasis incidence rate was 1,046 (95% confidence interval (95% CI) 524-2,096) per 100,000 person years in OTR and 656 (95% CI; 388-1,107) in immunocompetent patients, yielding an incidence rate ratio of 1...
February 6, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29405245/initial-results-of-secukinumab-drug-survival-in-patients-with-psoriasis-a-multicentre-daily-practice-cohort-study
#10
Juul M P A van den Reek, Lieke J van Vugt, Martijn B A van Doorn, Gayle E van der Kraaij, Wim J A de Kort, Georges P H Lucker, Barbara Horvath, M David Njoo, H Jorn Bovenschen, Paul M Ossenkoppele, Marjolein S de Bruin-Weller, Marjan de Groot, Roland Mommers, Ruud L M A Prevoo, Peter C M van de Kerkhof, Phyllis I Spuls, Wietske Kievit, Elke M G J de Jong
Interleukin 17-antagonist secukinumab demonstrated high efficacy for treatment of psoriasis in randomized controlled trials (RCTs). However, performance in daily practice may differ from trials. Drug survival is a comprehensive outcome covering effectiveness and safety, suitable for analyses of daily practice. The aim of this study was to evaluate drug survival of secukinumab in a daily practice psoriasis cohort. Data were collected from 13 hospitals. Drug survival was analysed using Kaplan-Meier survival curves, split for reason of discontinuation...
February 6, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29405244/isolated-adrenocorticotropic-hormone-deficiency-in-melanoma-patients-treated-with-nivolumab
#11
Seiya Kitano, Kazuki Tatsuno, Junichi Ishibe, Takatoshi Shimauchi, Toshiharu Fujiyama, Taisuke Ito, Noriyoshi Ogawa, Yoshiki Tokura
No abstract text is available yet for this article.
February 6, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29405243/characteristics-of-familial-melanoma-in-valencia-spain-based-on-the-presence-of-cdkn2a-mutations-and-mc1r-variants
#12
Claudia Huertas, Zaida Garcia-Casado, José Bañuls, Manuel Moragon, Vicente Oliver, Blanca Unamuno, Celia Requena, Rajiv Kumar, Eduardo Nagore
Melanoma results from a complex interplay between environmental factors and individual genetic susceptibility. Familial melanoma is attributable to predisposition genes with variable penetrance. The aim of this study was to identify differences between familial melanoma and sporadic cases in our population, based on the presence of CDKN2A mutations and MC1R variants. Comparing 107 patients with familial melanoma from 87 families (17% CDKN2A mutated) with 1,390 cases of sporadic melanomas, the former were younger and exhibited an increased prevalence of atypical naevi and squamous cell carcinoma (SCC)...
February 6, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29379979/propionibacterium-acnes-abundance-correlates-inversely-with-staphylococcus-aureus-data-from-atopic-dermatitis-skin-microbiome
#13
Wojciech Francuzik, Kristin Franke, Ralf R Schumann, Guido Heine, Margitta Worm
The microbiome may influence disease severity in atopic dermatitis. The skin of atopic dermatitis patients and healthy individuals was sampled in a standardized manner and the microbial composition analysed using next-generation sequencing. Optical density measurements were used to investigate bacterial growth under defined conditions in vitro. Lesional skin from patients with atopic dermatitis had a higher abundance of S. aureus and reduced quantities of Propionibacterium acnes and Lawsonella clevelandensis compared with non-lesional skin...
January 30, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29379978/outcome-of-combined-treatment-of-surgery-and-adjuvant-radio-therapy-in-merkel-cell-carcinoma
#14
Eckhard Fiedler, Dirk Vordermark
In recent analyses of Merkel cell carcinoma, prognosis is poor even in stages I and II. We performed a monocentric retrospective study of 37 consecutive cases with Merkel cell carcinoma stage I to III treated with a combination of surgery and adjuvant radiation to evaluate progression-free and overall survival. The median primary tumor diameter was 17.9 mm. Cases consisted of 31 primary tumors, of which 13 had negative sentinel lymph node biopsy (IA n = 10 and IIA n = 3) and 18 no sentinel lymph node biopsy (IB n = 15 and IIB n = 3), 2 tumors with positive sentinel lymph node biopsy (IIIA) and 4 with local macrometastasis (IIIB)...
January 30, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29379977/toe-gangrene-associated-with-macroangiopathy-in-systemic-sclerosis-a-case-series-on-the-unreliability-of-the-ankle-brachial-pressure-index
#15
Takashi Hashimoto, Takahiro Satoh, Hiroo Yokozeki
No abstract text is available yet for this article.
January 30, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29363715/early-relief-of-pruritus-in-atopic-dermatitis-with-crisaborole-ointment-a-non-steroidal-phosphodiesterase-4-inhibitor
#16
Gil Yosipovitch, Linda F Stein Gold, Mark G Lebwohl, Jonathan I Silverberg, Anna M Tallman, Lee T Zane
Pruritus occurs in all patients with atopic dermatitis and requires quick relief to reduce disease exacerbation and improve quality of life. Crisaborole ointment is a non-steroidal phosphodiesterase 4 inhibitor for the treatment of mild-to-moderate atopic dermatitis. This post hoc analysis explores crisaborole ointment for early relief of pruritus in patients with mild to moderate atopic dermatitis from 2 phase III studies. Patients received crisaborole or vehicle twice daily for 28 days. Pruritus was graded on a 4-point scale of none (0) to severe (3)...
January 24, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29362816/pyoderma-gangrenosum-under-dabrafenib-and-trametinib-for-metastatic-melanoma
#17
Mélanie Saint-Jean, Marie Le Moigne, Justine Daguze, Céline Bossard, Lucie Peuvrel, Gaëlle Quéreux, Brigitte Dréno
No abstract text is available yet for this article.
January 24, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29362815/2mcid-two-minimal-clinically-important-difference-a-new-twist-on-an-old-concept
#18
Faraz M Ali, M Sam Salek, Andrew Finlay
No abstract text is available yet for this article.
January 24, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29362814/longer-duration-of-untreated-psychosis-is-associated-with-poorer-outcomes-for-patients-with-delusional-infestation
#19
Dmitry V Romanov, Peter Lepping, Anthony Bewley, Markus Huber, Roland Freudenmann, Andrey Lvov, Stephen Bertel Squire, Eric Noorthoorn
We examined the association between the duration of untreated psychosis and outcome for patients with delusional infestation. This multi-centre international study included consecutive 211 patients. Illness severity was evaluated at first presentation and outcome was measured with the Clinical Global Impression scale (CGI) at base line and follow-up. A regression analysis showed a clear clinical and statistically significant association between shorter duration of untreated psychosis and better outcome at follow up...
January 24, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29362813/two-severe-cases-of-adult-onset-still-s-disease-with-persistent-pruritic-eruptions
#20
Yang Liu, Tetsuya Ikawa, Yayoi Tada, Takamitsu Tanaka, Takamitsu Ohnishi, Shinichi Watanabe, Daisuke Tsukui, Kurumi Asako, Hajime Kono
No abstract text is available yet for this article.
January 24, 2018: Acta Dermato-venereologica
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