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Acta Cytologica

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https://www.readbyqxmd.com/read/29136629/modified-alcohol-formalin-cell-block-technique-in-head-and-neck-pathology-diagnosis
#1
Karishma M Desai, Punnya V Angadi, Alka D Kale, Seema Hallikerimath
OBJECTIVES: Cell block preparation is a recognized technique in histopathological diagnosis. This technique aids in maintaining an intact architecture and reducing the diagnostic errors associated with fine-needle aspiration cytology. Numerous techniques have been put forth, but the need for an optimal technique for routine use in the laboratory still persists. The aim of our study was to establish a cell block technique which aids in the accurate diagnosis of head and neck pathology...
November 15, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/29136626/comparison-of-visual-inspection-with-acetic-acid-and-the-pap-smear-for-cervical-cancer-screening
#2
Parul Sinha, Pritika Srivastava, Anand Srivastava
OBJECTIVE: To evaluate the efficacy of visual inspection with acetic acid (VIA) in the early detection of cervical cancer and compare it with the Pap smear. STUDY DESIGN: This was a cross-sectional study conducted over a period of 3 months. A total of 316 patients who attended the Gynecology Outpatient Department of Era's Lucknow Medical College and Hospital, fulfilled the inclusion criteria, and gave their informed consent were included. RESULTS: VIA was found positive in 38 patients (12...
November 15, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/29136620/use-of-automated-analysis-of-cervical-cytology-for-the-detection-of-high-grade-squamous-intraepithelial-lesions-in-human-papillomavirus-positive-women-a-future-practice
#3
Pierre Vassilakos, Rosa Catarino, Patrick Petignat
No abstract text is available yet for this article.
November 15, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/29130942/high-grade-urothelial-carcinoma-on-urine-cytology-resembling-umbrella-cells
#4
Andrew A Renshaw, Edwin W Gould
CONTEXT: High-grade urothelial carcinoma (UC) cells have many appearances on urine cytology, but according to The Paris System, they can be easily distinguished from umbrella cells. OBJECTIVE: We aimed to define the incidence and appearance of high-grade UC cells that resemble umbrella cells in Cytospin preparations on urine cytology. RESULTS: Cytospin preparations from 331 cases with biopsy follow-up (230 benign/low-grade and 101 malignant [22 carcinoma in situ, 52 papillary, 19 invasive UC, 8 other] cases) were reviewed...
November 11, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/29130974/atypical-squamous-cells-in-liquid-based-cervical-cytology-microbiology-inflammatory-infiltrate-and-human-papillomavirus-dna-testing
#5
Geilson Gomes de Oliveira, Renata Mirian Nunes Eleutério, Ana Katherine Silveira Gonçalves, Paulo César Giraldo, José Eleutério
OBJECTIVE: The aim of this study was to assess the correlation between atypical squamous cells (ASC) and inflammatory infiltrate and vaginal microbiota using cervical liquid-based cytological (SurePath®) and high-risk human papillomavirus (HR-HPV) tests. STUDY DESIGN: A cross-sectional study was conducted using a 6-year database from a laboratory in Fortaleza (Brazil). Files from 1,346 ASC cases were divided into subgroups and results concerning inflammation and vaginal microorganisms diagnosed by cytology were compared with HR-HPV test results...
November 8, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/29130950/characteristics-of-false-negative-thyroid-fine-needle-aspirates
#6
Andrew A Renshaw, Edwin W Gould
INTRODUCTION: False-negative thyroid fine-needle aspirates (FNA) are not well characterized. METHODS: We correlated the results of all thyroid aspirations from 1997 to 2016 with histologic follow-up. RESULTS: There were 13,733 aspirates, 2,112 (15.3%) resections, and 678 malignancies (32.1%). Eighteen (2.7%) false-negative cases were identified (interpretation, n = 6; sampling, n = 7; and new nodules, n = 5). Interpretive false-negative cases were significantly less likely when the indeterminate rate was greater than 13% (p = 0...
November 4, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/29073594/gaining-an-accurate-diagnosis-a-multidisciplinary-approach
#7
Irina Shabalova
No abstract text is available yet for this article.
October 27, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/29069645/organized-cervical-cancer-screening-program-in-barretos-brazil-experience-in-18-municipalities-of-s%C3%A3-o-paulo-state
#8
Júlio César Possati-Resende, Fabiana de Lima Vazquez, Sinval Tadeu Biot, Edmundo Carvalho Mauad, Thais Talarico, José Humberto Tavares Guerreiro Fregnani, Adhemar Longatto-Filho
OBJECTIVES: The aim of this report is to demonstrate the Barretos Cancer Hospital initiative of organizational, laboratorial, and human resources training in the implementation of an organized cervical screening program in low-resource settings. METHODS: We developed a computational program to report all epidemiological, clinical, and laboratorial findings, and to trace all necessary information to recruit women for regular screening or for referral for complementary exams after liquid-based Pap test analyses...
October 26, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28977789/intraoperative-squash-and-touch-preparation-cytology-of-brain-lesions-stained-with-h-e-and-diff-quik%C3%A2-a-20-year-retrospective-analysis-and-comparative-literature-review
#9
Makoto Hamasaki, Karen H F Chang, Kazuki Nabeshima, Pamela S Tauchi-Nishi
OBJECTIVE: Squash preparation (SP) is a rapid technique for the intraoperative assessment of brain lesions. Only a few studies have employed touch preparation (TP) cytology and Diff-QuikTM (DQ) staining in conjunction with SP. Our study aimed to assess the diagnostic efficacy of SP of brain lesions at our institution, ascertain the additional effect of TP and DQ staining, examine factors affecting the sensitivity and specificity of our methods, and compare our findings with those of previous investigations...
October 5, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28954257/a-modified-direct-smear-processing-technique-employing-two-step-centrifugation-fixation-is-useful-for-detecting-high-grade-urothelial-carcinoma
#10
Yasuhiro Toyonaga, Kazuto Yamazaki, Yoshinori Koyama, Masatoshi Yamada, Yasuo Ishida
OBJECTIVE: To demonstrate the usefulness of a direct-smear processing technique employing two-step centrifugation/fixation processing (TSCFP) in the cytoscreening of high-grade urothelial carcinoma (HGUC). STUDY DESIGN: Using the T24 HGUC cell line, we compared the cell yield and the morphological preservation of preparations concurrently processed by direct-smear, SurePath, ThinPrep, and TSCFP techniques. A total of 287 urine cytology cases subjected to TSCFP over a period of 6 years were reviewed and reclassified according to the Paris System for Reporting Urinary Cytology (PSRUC) and correlated with histology results...
September 28, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28946148/assessment-of-clinically-suspected-tubercular-lymphadenopathy-by-real-time-pcr-compared-to-non-molecular-methods-on-lymph-node-aspirates
#11
Vivek Gupta, Arvind Bhake
BACKGROUND: The diagnosis of tubercular lymphadenitis (TBLN) is challenging. This study assesses the role of diagnostic intervention with real-time PCR in clinically suspected tubercular lymphadenopathy in relation to cytology and microbiological methods. METHODS: The cross-sectional study involved 214 patients, and PCR, cytology, and Ziehl-Neelsen (ZN) staining was performed on aspirates. The findings were compared with culture on Lowenstein-Jensen medium. The overall concordance of cytology and PCR, both individually and combined, was calculated...
September 26, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28926837/vascular-proliferation-associated-with-florid-granulomatous-reaction-after-fna-in-a-benign-thyroid-nodule
#12
José Cândido Caldeira Xavier-Júnior, Deolino João Camilo-Júnior, Solange Correa Garcia Pires D'ávilla, Neivio José Mattar
No abstract text is available yet for this article.
September 20, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28848129/clinical-utility-of-endometrial-cell-block-cytology-in-postmenopausal-women
#13
Naoyo Nishida, Fumihiro Murakami, Aki Kuroda, Yoshitaka Sakamoto, Kazuto Tasaki, Shingo Tasaki, Takuya Shimomura
OBJECTIVE: To investigate the diagnostic utility of endometrial (EM) cell block (CB) cytology for the detection of intrauterine malignancy in postmenopausal women. METHODS: We reviewed the medical records of 104 postmenopausal women between January 2012 and November 2014. We reviewed symptoms upon admission, body mass index, parity, transvaginal ultrasonographic findings, and histopathological results based on CB and conventional cytology. RESULTS: The mean age was 62...
August 23, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28848083/use-of-exfoliative-specimens-and-fine-needle-aspiration-smears-for-mutation-testing-in-lung-adenocarcinoma
#14
Deepali Jain, Vijayakumar S Ramachandrappa, Varsha Singh, Prabhat S Malik, Karan Madan, Mohammed Faruq, Randeep Guleria
OBJECTIVE: Cytology specimens are considered to be a promising alternative for detecting driver mutations in lung cancer patients. We aimed to explore the suitability and utility of various cytology samples of non-small-cell lung cancer (NSCLC) patients for mutation testing. In addition to mutation detection, the importance of preanalytic factors was discussed. DESIGN: A total of 116 cytology samples including 32 controls comprising pleural effusions, bronchial washings, and direct fine-needle aspiration (FNA) smears were included in the study for the detection of EGFR, KRAS, and Her-2/neu gene mutations...
August 22, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28746917/cytological-features-of-the-large-cell-variant-of-small-cell-ovarian-carcinoma-in-young-patients-with-hypercalcemia-histological-findings-and-review-of-the-literature
#15
Helen J Trichia, Paraskevi Tziakou, Dimitrios C Papatheodorou, Joanna Lekka
OBJECTIVE: To present the cytological features of a very rare and lethal ovarian neoplasm occurring in the young. STUDY DESIGN: We reviewed the cytological findings as they presented in touch imprints obtained from an ovarian mass sent to our department for frozen section investigation. RESULTS: Smears were highly cellular. The cells were of intermediate size with a moderate amount of microvacuolated, pale, or eosinophilic cytoplasm with indistinct cell borders...
July 27, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28738387/false-negative-rate-of-papanicolaou-testing-a-national-survey-from-the-thai-society-of-cytology
#16
Supinda Koonmee, Andrey Bychkov, Somruetai Shuangshoti, Kanyaprin Bhummichitra, Wanwisa Himakhun, Anant Karalak, Samreung Rangdaeng
OBJECTIVE: To evaluate the performance of Papanicolaou smear screening in Thailand at the national level, and to propose recommendations for continuing quality control. STUDY DESIGN: This study was conducted by The Thai Society of Cytology and involved 124 laboratories in 76 provinces during 2010-2014. Random sampling suggested recalling of 10% of slides defined as negative at routine screenings (10% random rescreening [R10] model) directly from the reading unit...
July 25, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28738381/cytological-criteria-to-distinguish-phyllodes-tumour-of-the-breast-from-fibroadenoma
#17
Robert M Maritz, Pamela M Michelow
OBJECTIVE: To determine whether there are significant differences between fibroadenomas and phyllodes tumours with regard to selected cytomorphological features. STUDY DESIGN: A 10-year retrospective review was performed of patients who underwent excision of a fibroadenoma or phyllodes tumour and in whom a preoperative fine-needle aspiration was performed. The following cytological criteria were assessed: number of stromal and epithelial fragments, stromal-to-epithelial ratio, stromal cellularity, stromal borders, stromal atypia, and proportion of background wavy spindled cells...
July 25, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28738326/difficulty-in-the-cytodiagnosis-of-mammary-analogue-secretory-carcinoma-survey-of-109-cytologists-with-a-case-originating-from-a-minor-salivary-gland
#18
Keita Kai, Akimichi Minesaki, Kumiko Suzuki, Mikio Monji, Mitsuo Nakamura, Hisayuki Tsugitomi, Yuichiro Kuratomi, Shinichi Aishima
BACKGROUND: Mammary analogue secretory carcinoma (MASC) of the salivary gland shows morphologic similarities and shares an immunophenotype and characteristic ETV6-NTRK3 translocation with secretory carcinoma of the breast. We present a buccal case of MASC along with a survey-based debate about its cytologic diagnosis by fine-needle aspiration (FNA). CASE: FNA of the buccal nodule of a 58-year-old Japanese man was initially performed by 3 cytologists who gave different assessments of the Papanicolaou classification (i...
July 25, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28564641/the-role-of-self-collection-by-vaginal-lavage-for-the-detection-of-hpv-and-high-grade-intraepithelial-neoplasia
#19
Larissa de Melo Kuil, Adriana Tarla Lorenzi, Maíra Degiovani Stein, Júlio César Possati Resende, Márcio Antoniazzi, Adhemar Longatto-Filho, Christóvam Scapulatempo-Neto, José Humberto Tavares Guerreiro Fregnani
OBJECTIVE: To compare the results of cervical cytology and high-risk HPV tests using samples obtained using two different collection modalities in a population of Brazilian women: self-collection (vaginal lavage) and cervical Pap testing. METHODS: We enrolled 204 women who were aged 18-64 years and had previously obtained abnormal cervical cytology test results; 83.8% of them agreed to participate. The sample was divided into two aliquots: one for the cytological study and one for the molecular analysis of high-risk HPV...
June 1, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28554176/fine-needle-aspiration-of-metastatic-central-type-primitive-neuroectodermal-tumors-in-patients-with-a-germ-cell-tumor
#20
Shaoxiong Chen, Muhammad Idrees, Jingmei Lin, Howard H Wu
OBJECTIVE: Central type primitive neuroectodermal tumors (PNET) are some of the most frequent somatic type tumors derived from germ cell tumors and can metastasize. We studied the cytomorphological features of metastatic central type PNET by fine-needle aspiration (FNA). MATERIALS AND METHODS: A computerized search of our laboratory information system was performed for the 9-year period from 2005 through 2014 to identify all cytology cases in which a diagnosis of metastatic central type PNET had been rendered...
May 30, 2017: Acta Cytologica
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