Read by QxMD icon Read


Anna Prigitano, Caterina Cavanna, Marco Passera, Cristina Ossi, Eugenio Sala, Gianluigi Lombardi, Anna Grancini, Concetta De Luca, Simone Bramati, Marina Gelmi, Milvana Tejada, Romualdo Grande, Claudio Farina, Fabiola Lallitto, Anna Maria Tortorano
PURPOSE: The aim of this study was to monitor recent changes in the epidemiology of candidemia and in the antifungal susceptibility profiles of Candida isolates in one Italian region (Lombardy) in 2014-2015 in comparison with two other studies performed in the same area in 1997-1999 and in 2009. METHODS: A laboratory-based surveillance was conducted in 11 microbiology laboratories. Identification of Candida isolates from 868 episodes and antifungal susceptibility testing (YeastOne) was performed locally...
October 17, 2016: Infection
Tetsuro Kobayashi, Kayoko Hayakawa
No abstract text is available yet for this article.
October 17, 2016: Infection
Chi Shao, Peng Wang, Ruie Feng, Xuefeng Sun
No abstract text is available yet for this article.
October 15, 2016: Infection
Pernille Bejer Nordentoft, Thomas Engell-Sørensen, Sanne Jespersen, Faustino Gomes Correia, Candida Medina, David da Silva Té, Lars Østergaard, Alex Lund Laursen, Christian Wejse, Bo Langhoff Hønge
PURPOSE: The objective of this study was to ascertain vital status of patients considered lost to follow-up at an HIV clinic in Guinea-Bissau, and describe reasons for loss to follow-up (LTFU). METHODS: This study was a cross-sectional sample of a prospective cohort, carried out between May 15, 2013, and January 31, 2014. Patients lost to follow-up, who lived within the area of the Bandim Health Project, a demographic surveillance site (DSS), were eligible for inclusion...
October 14, 2016: Infection
Alfonso J Rodriguez-Morales, Maria Leonor Galindo-Marquez, Carlos Julian García-Loaiza, Juan Alejandro Sabogal-Roman, Santiago Marin-Loaiza, Andrés F Ayala, Guillermo J Lagos-Grisales, Carlos O Lozada-Riascos, Esteban Parra-Valencia, Jorge H Rojas-Palacios, Eduardo López, Pío López, Martin P Grobusch
OBJECTIVE: Geographical information systems (GIS) use for development of epidemiological maps in tropical diseases is increasingly frequently utilized. Here, we apply this technique to map the current Zika virus (ZIKV) outbreak in Colombia. METHODS: Surveillance cases data of the ongoing epidemic of ZIKV in Valle del Cauca department and its capital, Cali (2015-2016), were used to estimate cumulated incidence rates (cases/100,000 population) to develop the first maps in the department and it municipalities...
October 14, 2016: Infection
Miki Nagao, Masaki Yamamoto, Yasufumi Matsumura, Isao Yokota, Shunji Takakura, Satoshi Teramukai, Satoshi Ichiyama
PURPOSE: Staphylococcus aureus bacteremia (SAB) is a serious clinical condition associated with high morbidity and mortality. Recent studies have revealed that adherence to evidence-based quality-of-care indicators (QCIs) for the management of SAB could result in reduced mortality. We aimed to determine whether compliance with QCIs was associated with mortality and whether compliance with QCIs predicted the mortality of patients with SAB. METHODS: In a university hospital in Kyoto, Japan, SAB patients, who survived at least 14 days after positive blood cultures were analyzed from 2006 to 2014 to assess their compliance with QCIs and the trend in mortality...
October 5, 2016: Infection
M Martinot, M Mohseni-Zadeh, E Candolfi
No abstract text is available yet for this article.
September 28, 2016: Infection
Alberto Hernández-Tejedor, Carmen Débora Merino-Vega, Alfredo Martín-Vivas, Rafael Ruiz de Luna-González, Alberto Delgado-Iribarren, Ángeles Gabán-Díez, Ignacio Temprano-Gómez, Natalia de la Calle-Pedrosa, Ana Isabel González-Jiménez, Alejandro Algora-Weber
INTRODUCTION: Ceftolozane/tazobactam is a novel antibiotic approved for the treatment of complicated intra-abdominal and complicated urinary tract infections. CASE DESCRIPTION: We describe the use of off-label ceftolozane/tazobactam in the management of a multidrug-resistant Pseudomonas aeruginosa bacteremia that was already being treated with colistin and amikacin, the only active antibiotics according to the antibiogram.
September 26, 2016: Infection
Florian Hitzenbichler, Michaela Simon, Bernd Salzberger, Frank Hanses
PURPOSE: We retrospectively evaluated blood culture (BC) isolates of coagulase-negative staphylococci other than Staphylococcus epidermidis (NonSe-CoNS) for clinical relevance at a tertiary care hospital in Germany from January 2011 to September 2015. METHODS: Clinical data were correlated to microbiological results based on medical records. Infection was considered likely if (1) no other infection and (2) two or more isolates of the same species were present and (3) symptoms ameliorated after therapy...
September 22, 2016: Infection
Giorgio Fedele, Maria Carollo, Raffaella Palazzo, Paola Stefanelli, Elisabetta Pandolfi, Francesco Gesualdo, Alberto Eugenio Tozzi, Rita Carsetti, Alberto Villani, Ambra Nicolai, Fabio Midulla, Clara Maria Ausiello
PURPOSE: This study was planned to collect evidences of familial pertussis transmission to infants younger than 6 months of age. Understanding the dynamics of transmission of pertussis in families is essential to plan effective prevention strategies that could be integrated in pertussis control. METHODS: The seroprevalence of IgG antibodies to pertussis toxin (PT-IgG) and prolonged cough symptoms were evaluated in parents of 55 infants aged <6 months hospitalized for confirmed pertussis...
September 10, 2016: Infection
Yongqiong Deng, Hong Zhao, Jiyuan Zhou, Linlin Yan, Guiqiang Wang
PURPOSE: To investigate the association between serum complement 5a (C5a) concentration and liver fibrosis and cirrhosis in a large cohort of patients chronically infected with hepatitis B virus (HBV). METHODS: Five hundred and eight patients with chronic HBV infection undergoing liver biopsy were included. Serum concentrations of C5a was measured by Luminex screening system. Ishak histological system was obtained. RESULTS: C5a levels were negatively associated with liver fibrosis stages and significantly declined in patients with severe fibrosis and cirrhosis (P < 0...
September 7, 2016: Infection
Shuyi Chen, Huawei Gu, Chunli Sun, Haiying Wang, Jufang Wang
BACKGROUND: Clostridium difficile is an anaerobic, spore-forming and Gram-positive bacillus. It is the major cause of antibiotic-associated diarrhea prevailing in hospital settings. The morbidity and mortality of C. difficile infection (CDI) has increased significantly due to the emergence of hypervirulent strains. Because of the poor clinical different between CDI and other causes of hospital-acquired diarrhea, laboratory test for C. difficile is an important intervention for diagnosis of CDI...
September 6, 2016: Infection
Franklin Correa Barcellos, Bruno Pereira Nunes, Luciana Jorge Valle, Thiago Lopes, Bianca Orlando, Cintia Scherer, Marcia Nunes, Gabriela Araújo Duarte, Maristela Böhlke
BACKGROUND: Central venous catheters (CVC) are the only option when hemodialysis is needed for patients without definitive vascular access. However, CVC is associated with complications, such as infection, thrombosis, and dysfunction, leading to higher mortality and expenditures. The aim of this study was to compare the effectiveness of 30 % trisodium citrate (TSC30 %) with heparin as CVC lock solutions in preventing catheter-related bloodstream infections (CRBSI) and dysfunction in hemodialysis patients...
August 29, 2016: Infection
Laura Barrado, Carmen Ezpeleta, José Miguel Rubio, Carmen Martín, José Manuel Azcona, Miren Arteaga, Xabier Beristain, Ana Navascués, Eva Ongay, Jesús Castilla
In 2014, an autochthonous case of introduced malaria caused by Plasmodium vivax was identified in Spain. The strain that infected this patient was identical to that of a prior imported case from Pakistan. This is the first case where the source of infection could be identified since elimination in Spain.
August 26, 2016: Infection
J Katchanov, S Kluge, C R MacKenzie, Achim J Kaasch
No abstract text is available yet for this article.
August 19, 2016: Infection
Seungjin Lim, Doo Ryeon Chung, Yeon-Sook Kim, Kyung Mok Sohn, Seung-Ji Kang, Sook-In Jung, Shin-Woo Kim, Hyun Ha Chang, Seung Soon Lee, In-Gyu Bae, Chisook Moon, Ji-Young Rhee, Jin Seo Lee, Hyun Kyun Ki, Hyun Ah Kim, Seong Yeol Ryu, Joon-Sup Yeom, Jun Seong Son, Soo-Youn Moon, Ki Tae Kwon, Hyuck Lee, Sang Taek Heo, Cheol-In Kang, Kyong Ran Peck, Jae-Hoon Song
PURPOSE: Various immunocompromised conditions increase the risk of meningitis caused by Listeria monocytogenes. However, the relative importance of these risk factors has not been well established. We determined the risk factors that predict meningitis due to L. monocytogenes compared to that caused by Streptococcus pneumoniae. METHODS: A nationwide multicenter case-control study was conducted in Korea. Cases of meningitis caused by L. monocytogenes between 1998 and 2013 were included...
August 19, 2016: Infection
Alexandra Jablonka, Georg M N Behrens, Marcus Stange, Christian Dopfer, Ulrike Grote, Gesine Hansen, Reinhold Ernst Schmidt, Christine Happle
BACKGROUND: Current political crises in the Middle East and economic discrepancies led millions of people to leave their home countries and to flee to Western Europe. This development raises unexpected challenges for receiving health care systems. Although pan-European initiatives strive for updated and optimized vaccination strategies, little data on immunity against vaccine-preventable diseases in the current refugee population exist. METHODS: We quantified serum IgG against tetanus and diphtheria (TD) in n = 678 refugees currently seeking shelter in six German refugee centers...
August 19, 2016: Infection
A Zoufaly, C Kraft, C Schmidbauer, E Puchhammer-Stoeckl
PURPOSE: Treatment guidelines often do not advocate testing for integrase inhibitor resistance associated mutations (IRAM) before initiation of first line ART given the extremely low prevalence of mutations found in older surveillance studies. We aimed to describe the prevalence of IRAM in Austrian patients recently diagnosed with HIV in the 5 years following introduction of integrase inhibitors and to analyse trends and factors associated with their detection. METHODS: Samples of antiretroviral treatment (ART) naïve patients recently diagnosed with HIV in Austria between 2008 and 2013 were analysed for the existence of IRAM and drug penalty scores were calculated to estimate response to drugs...
August 16, 2016: Infection
Katrin Henkel, Peter Lange, Helmut Eiffert, Roland Nau, Annette Spreer
PURPOSE: Peripheral facial nerve palsy (FP) is the most common single nerve affection. Most cases are idiopathic, but a relevant fraction is caused by potentially treatable aetiologies including infections. Not all current diagnosis and treatment guidelines recommend routine cerebrospinal fluid (CSF) analysis in the diagnostic workup of this symptom. In this study, we evaluated frequency of aetiologies and relevance of CSF analysis in an interdisciplinary cohort. METHODS: We retrospectively analysed all cases of newly diagnosed FP treated at a German university medical centre in a 3-year period...
August 16, 2016: Infection
T Ruggiero, E Burdino, A Calcagno, S Bonora, L Boglione, G Di Perri, V Ghisetti
PURPOSE: Data on the frequency of HCV naturally occurring drug-resistant variants (RAVs) at baseline in HIV/HCV coinfected patients are scarce. METHODS: NS3-HCV RAVs were studied by full-population direct sequencing from plasma specimens of 345 DAA-naïve patients with HCV chronic hepatitis (159 of them with HIV/HCV-coinfection). RESULTS: NS3 RAVs were identified in 31.5 % of patients, with a significant proportion of HIV/HCV coinfected DAA-naïve patients compared to those with HCV monoinfection (38 vs...
August 13, 2016: Infection
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"