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https://www.readbyqxmd.com/read/27909896/detection-of-shigella-sonnei-in-a-respiratory-specimen-in-a-patient-with-subacute-atypical-pneumonia
#1
Hiwa Nahid, Désirée Staub, Herbert Hächler, Werner C Albrich
BACKGROUND: Pneumonia caused by shigellosis with or without typical dysentery in immunocompetent patients is an uncommon entity. CASE REPORT: We describe a case of pneumonia in an immunocompetent, previously healthy middle-aged man from Switzerland without relevant travel history which was presumably caused by Shigella sonnei. He was originally admitted for suspected lung cancer. The clinical picture was remarkable as the patient presented with cough and purulent sputum production, but otherwise no classical signs of pneumonia...
December 1, 2016: Infection
https://www.readbyqxmd.com/read/27909895/invasive-cutaneous-infection-due-to-scopulariopsis-brevicaulis-unsuccessfully-treated-with-high-dose-micafungin-in-a-neutropenic-patient
#2
Daniela Gavril, Paul-Louis Woerther, Aicha Ben Lakhdar, Linda Mahjoubi, Emilie Routier, Elisabeth Chachaty, Bertrand Gachot, Stephane De Botton, Jean-Baptiste Micol, Christophe Willekens
Scopulariopsis brevicaulis onychomycosis with local cutaneous invasion was diagnosed in an acute leukemia patient and unsuccessfully treated with high-dose micafungin, based on antifungal susceptibility testing. This case should alert clinicians to the possible severe evolution of onychomycosis in neutropenic patients and suggests that surgery should be preferred in such a situation.
December 1, 2016: Infection
https://www.readbyqxmd.com/read/27878519/polymicrobial-pulmonary-infections-in-cancer-patients-with-underlying-solid-tumors
#3
LETTER
Kenneth V I Rolston
No abstract text is available yet for this article.
November 22, 2016: Infection
https://www.readbyqxmd.com/read/27873166/a-dangerous-hobby-erysipelothrix-rhusiopathiae-bacteremia-most-probably-acquired-from-freshwater-aquarium-fish-handling
#4
E Asimaki, O Nolte, G Overesch, C Strahm
Erysipelothrix rhusiopathiae is a facultative anaerobic Gram-positive rod that occurs widely in nature and is best known in veterinary medicine for causing swine erysipelas. In humans, infections are rare and mainly considered as occupationally acquired zoonosis. A case of E. rhusiopathiae bacteremia most likely associated with home freshwater aquarium handling is reported. The route of transmission was probably a cut with the dorsal fin of a dead pet fish. A short review of clinical presentations, therapeutic considerations and pitfalls of E...
November 21, 2016: Infection
https://www.readbyqxmd.com/read/27866368/does-serum-procalcitonin-aid-in-the-diagnosis-of-bloodstream-infection-regardless-of-whether-patients-exhibit-the-systemic-inflammatory-response-syndrome
#5
Rashi Arora, James P Campbell, Gyorgy Simon, Nishant Sahni
BACKGROUND: Physicians frequently rely on the systemic inflammatory response syndrome (SIRS) criteria to detect bloodstream infections (BSIs). We evaluated the diagnostic performance of procalcitonin (PCT) in detecting BSI in patients with and without SIRS. METHODS: We tested the association between BSI, serum PCT levels, contemporaneous SIRS scores and serum lactate using logistic regression in a dataset of 4279 patients. The diagnostic performance of these variables was assessed...
November 19, 2016: Infection
https://www.readbyqxmd.com/read/27866367/risk-for-latent-and-active-tuberculosis-in-germany
#6
Christian Herzmann, Giovanni Sotgiu, Oswald Bellinger, Roland Diel, Silke Gerdes, Udo Goetsch, Helga Heykes-Uden, Tom Schaberg, Christoph Lange
PURPOSE: Few individuals that are latently infected with M. tuberculosis latent tuberculosis infection(LTBI) progress to active disease. We investigated risk factors for LTBI and active pulmonary tuberculosis (PTB) in Germany. METHODS: Healthy household contacts (HHCs), health care workers (HCWs) exposed to M. tuberculosis and PTB patients were recruited at 18 German centres. Interferon-γ release assay (IGRA) testing was performed. LTBI risk factors were evaluated by comparing IGRA-positive with IGRA-negative contacts...
November 19, 2016: Infection
https://www.readbyqxmd.com/read/27854063/treatment-with-daclatasvir-and-sofosbuvir-for-24%C3%A2-weeks-without-ribavirin-in-cirrhotic-patients-who-failed-first-generation-protease-inhibitors
#7
Lucio Boglione, Simone Mornese Pinna, Chiara Simona Cardellino, Amedeo De Nicolò, Jessica Cusato, Chiara Carcieri, Giuseppe Cariti, Giovanni Di Perri, Antonio D'Avolio
BACKGROUND: Treatment of patients with chronic hepatitis C who failed the triple therapy with first generation of protease inhibitors is not still defined. The combined use of sofosbuvir (SOF) and daclatasvir (DCV) seems to be promising due to higher genetic barrier, good tolerance and effectiveness. METHODS: We described the treatment with this drug combination in a real-life cohort of 20 cirrhotic patients with genotype 1 who failed the triple therapy. RESULTS: 18 of them (90%) with Child-Pugh A, 11 (55%) with genotype 1a, 17 (85%) with more than 1 and 8 (40%) with more than 2 previous failed treatment; all patients had at baseline NS3 resistance-associated variants related to triple therapy failure...
November 16, 2016: Infection
https://www.readbyqxmd.com/read/27848164/septic-arthritis-due-to-legionella-cincinnatiensis-case-report-and-review-of-the-literature
#8
Florian Banderet, Annette Blaich, Evelin Soleman, Valeria Gaia, Michael Osthoff
Legionella spp. are an important cause of pulmonary and rarely extrapulmonary infections. L. cincinnatiensis has only been implicated in five cases to date. We herein report the first case of L. cincinnatiensis septic arthritis in a 90-year old lady with a past medical history of chronic kidney disease. She developed septic arthritis of her left wrist after having received intraarticular corticosteroid injections and oral corticosteroids administered for presumed chondrocalcinosis. Appropriate antimicrobial treatment of L...
November 15, 2016: Infection
https://www.readbyqxmd.com/read/27837335/vibrio-cholerae-non-o1-non-o139-bacteraemia-associated-with-pneumonia-italy-2016
#9
Serena Marinello, Giulia Marini, Giancarlo Parisi, Lorena Gottardello, Lucia Rossi, Valeria Besutti, Anna Maria Cattelan
This paper describes an elderly male patient, living in the Veneto Region, Italy, who developed Vibrio cholerae bacteraemia and pneumonia. Some days previously, while on holiday in the Lagoon of Venice, he had been collecting clams in seawater, during which he suffered small abrasions of the skin. On admission to hospital, he was confused, had fever and a cough, but neither diarrhoea nor signs of gastroenteritis were found. Both blood and stool cultures grew V. cholerae of non-O1 non-O-139 type, and the patient recovered after prompt administration of intravenous ceftriaxone for 2 weeks...
November 11, 2016: Infection
https://www.readbyqxmd.com/read/27830524/association-of-hiv-infection-with-extrapulmonary-tuberculosis-a-systematic-review
#10
REVIEW
Rupak Shivakoti, Davina Sharma, Gabeena Mamoon, Kiemanh Pham
PURPOSE: HIV/AIDS is a known risk factor for the development of pulmonary tuberculosis (PTB). However, the association is less clear between HIV and extrapulmonary tuberculosis (EPTB). We conducted a systematic review to determine the association between HIV and EPTB. METHODS: We searched the electronic databases Medline, Embase, and relevant conference literature using defined search terms for EPTB and HIV. Only publications in English and only studies reporting adjusted estimates were included, while our search criteria did not include restriction by age or geographic location of study participants...
November 9, 2016: Infection
https://www.readbyqxmd.com/read/27826871/anti-n-methyl-d-aspartate-receptor-encephalitis-after-herpes-simplex-virus-associated-encephalitis-an-emerging-disease-with-diagnosis-and-therapeutic-challenges
#11
Flora Schein, Amandine Gagneux-Brunon, Jean-Christophe Antoine, Sylvie Lavernhe, Sylvie Pillet, Stéphane Paul, Anne Frésard, Claire Boutet, Rémi Grange, Céline Cazorla, Frédéric Lucht, Elisabeth Botelho-Nevers
INTRODUCTION: Morbidity and mortality of Herpes simplex virus encephalitis (HSE) remain high. Relapses of neurological signs may occur after initial clinical improvement under acyclovir treatment. METHODS: We report here a case of post-HSE anti-N-methyl-d-aspartate receptor-mediated encephalitis in an adult and perform a systematic search on PubMed to identify other cases in adults. RESULTS: We identified 11 previously published cases, to discuss diagnostic and therapeutic management...
November 8, 2016: Infection
https://www.readbyqxmd.com/read/27817147/hepatitis-delta-infection-in-italian-patients-towards-the-end-of-the-story
#12
Tommaso Stroffolini, Evangelista Sagnelli, Caterina Sagnelli, Maurizio Russello, Massimo De Luca, Floriano Rosina, Bruno Cacopardo, Giuseppina Brancaccio, Caterina Furlan, Giovanni Battista Gaeta, Anna Licata, Piero Luigi Almasio
BACKGROUND: The endemicity of hepatitis delta virus infection in Italy has decreased in the last decades. AIM: To evaluate the current epidemiology of chronic delta infection in Italy and to compare the present findings with the corresponding figures from the previous studies. METHODS: A cross-sectional study involving 16 referral centres scattered all over the country in 2014. RESULTS: Out of the 513 hepatitis B surface antigen-positive subjects enrolled, 61 (11...
November 5, 2016: Infection
https://www.readbyqxmd.com/read/27812890/human-visceral-pentastomiasis-armillifer-armillatus
#13
Anna Beltrame, Dario Raniero, Zeno Bisoffi, Lawrence R Ash
No abstract text is available yet for this article.
November 3, 2016: Infection
https://www.readbyqxmd.com/read/27798774/detection-of-transrenal-dna-for-the-diagnosis-of-pulmonary-tuberculosis-and-treatment-monitoring
#14
Ines Labugger, Jan Heyckendorf, Stefan Dees, Emilia Häussinger, Christian Herzmann, Thomas A Kohl, Elvira Richter, Eric Rivera-Milla, Christoph Lange
PURPOSE: Molecular diagnostics of patients with MTB tuberculosis from urine samples. METHODS: We developed a new molecular assay based on the detection of M. tuberculosis-specific transrenal DNA (trDNA) and tested it for the diagnosis of active tuberculosis at the initiation of anti-tuberculosis therapy and during treatment follow-up. RESULTS: The overall sensitivity of trDNA was 96 and 100% when smear-microscopy and trDNA was combined. In a subset of TB treatment naïve patients (n = 11) sensitivity and specificity of trDNA was 64 and 100%, respectively...
October 31, 2016: Infection
https://www.readbyqxmd.com/read/27796847/four-clusters-of-trichostrongylus-infection-diagnosed-in-a-single-center-in-italy
#15
Dora Buonfrate, Andrea Angheben, Federico Gobbi, Manuela Mistretta, Monica Degani, Zeno Bisoffi
Trichostrongylus spp. are parasites that are seldom recognized as a cause of eosinophilia and gastroenteric symptoms in industrialized countries. The index of suspicion raises when several members of a same household present eosinophilia. We report four clusters of Trichostrongylus infection diagnosed in a single center, in northern Italy. Patients came from four different provinces of three Italian Regions. Some patients presented symptoms (abdominal pain and diarrhea were the most frequent ones, reported by 67 and 42% of our patients, respectively), while other were asymptomatic...
October 27, 2016: Infection
https://www.readbyqxmd.com/read/27778190/synchronous-multifocal-necrotizing-fasciitis-prognostic-factors-a-retrospective-case-series-study-in-a-single-center
#16
Ching-Yu Lee, Yen-Yao Li, Tsan-Wen Huang, Tsung-Yu Huang, Wei-Hsiu Hsu, Yao-Hung Tsai, Jou-Chen Huang, Kuo-Chin Huang
PURPOSE: No reports have been published on synchronous multifocal necrotizing fasciitis (SMNF), a multifocal presence of necrotizing fasciitis in different extremities. We evaluated the clinical characteristics and outcomes of SMNF. METHODS: Eighteen patients (14 men, 4 women; mean age: 59 years) diagnosed with SMNF of the extremities between January 2004 to December 2012 were enrolled and evaluated. RESULTS: Vibrio species were the most commonly (78%; n = 14) isolated; others were two cases (11%) of Aeromonas spp...
October 24, 2016: Infection
https://www.readbyqxmd.com/read/27771866/histopathology-of-valves-in-infective-endocarditis-diagnostic-criteria-and-treatment-considerations
#17
Tatiana J D Brandão, Carolina A Januario-da-Silva, Marcelo G Correia, Monica Zappa, Jaime A Abrantes, Angela M R Dantas, Wilma Golebiovski, Giovanna Ianini F Barbosa, Clara Weksler, Cristiane C Lamas
BACKGROUND: Infective endocarditis (IE) is a severe disease. Pathogen isolation is fundamental so as to treat effectively and reduce morbidity and mortality. Blood and valve culture and histopathology (HP) are routinely employed for this purpose. Valve HP is the gold standard for diagnosis. OBJECTIVES: To determine the sensitivity and specificity of clinical criteria for IE (the modified Duke and the St Thomas' minor modifications, STH) of blood and valve culture compared to valve HP, and to evaluate antibiotic treatment duration...
October 22, 2016: Infection
https://www.readbyqxmd.com/read/27753001/cand-lo-2014-15-study-changing-epidemiology-of-candidemia-in-lombardy-italy
#18
Anna Prigitano, Caterina Cavanna, Marco Passera, Cristina Ossi, Eugenio Sala, Gianluigi Lombardi, Anna Grancini, Concetta De Luca, Simone Bramati, Marina Gelmi, Milvana Tejada, Romualdo Grande, Claudio Farina, Fabiola Lallitto, Anna Maria Tortorano
PURPOSE: The aim of this study was to monitor recent changes in the epidemiology of candidemia and in the antifungal susceptibility profiles of Candida isolates in one Italian region (Lombardy) in 2014-2015 in comparison with two other studies performed in the same area in 1997-1999 and in 2009. METHODS: A laboratory-based surveillance was conducted in 11 microbiology laboratories. Identification of Candida isolates from 868 episodes and antifungal susceptibility testing (YeastOne) was performed locally...
October 17, 2016: Infection
https://www.readbyqxmd.com/read/27753000/minocycline-induced-skin-pigmentation
#19
Tetsuro Kobayashi, Kayoko Hayakawa
No abstract text is available yet for this article.
October 17, 2016: Infection
https://www.readbyqxmd.com/read/27744537/endobronchial-actinomycosis-secondary-to-foreign-body-aspiration
#20
Chi Shao, Peng Wang, Ruie Feng, Xuefeng Sun
No abstract text is available yet for this article.
October 15, 2016: Infection
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