journal
MENU ▼
Read by QxMD icon Read
search

Annals of Biomedical Engineering

journal
https://www.readbyqxmd.com/read/28324193/hemodynamic-characterization-of-peripheral-arterio-venous-malformations
#1
Sabrina Frey, A Haine, R Kammer, H von Tengg-Kobligk, D Obrist, I Baumgartner
Peripheral arterio-venous malformations (pAVMs) are congenital vascular anomalies that require treatment, due to their severe clinical consequences. The complexity of lesions often leads to misdiagnosis and ill-planned treatments. To improve disease management, we developed a computational model to quantify the hemodynamic effects of key angioarchitectural features of pAVMs. Hemodynamic results were used to predict the transport of contrast agent (CA), which allowed us to compare our findings to digital subtraction angiography (DSA) recordings of patients...
March 21, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28321583/microfluidic-encapsulation-of-ovarian-follicles-for-3d-culture
#2
Xiaoming He
The ovarian follicle that contains one single oocyte is the fundamental functional tissue unit of mammalian ovary. Therefore, isolation and in vitro culture of ovarian follicles to obtain fertilizable oocytes are regarded as a promising strategy for women to combat infertility. In this communication, we performed a brief survey of studies on microfluidic encapsulation of ovarian follicles in core-shell hydrogel microcapsules for biomimetic 3D culture. These studies highlighted that recapitulation of the mechanical heterogeneity of the extracellular matrix in ovary is crucial for in vitro culture to develop early pre-antral follicles to the antral stage, and for the release of cumulus-oocyte complex (COC) from antral follicles in vitro...
March 20, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28293752/acoustic-emission-signatures-during-failure-of-vertebra-and-long-bone
#3
Brian D Goodwin, Frank A Pintar, Narayan Yoganandan
Clinical classification of an injury has traditionally involved medical imaging, patient history, and physical examination. The pathogenesis or process of injury has been viewed as a crucial component to estimating fracture stability and direct treatment. However, injury classification systems generally exclude pathogenesis and injury mechanisms because these components are often difficult to elucidate. Furthermore, the development of bone damage relative to the mechanical response is difficult to quantify, which limits the ability to define injury and develop injury criteria...
March 14, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28293751/linear-and-nonlinear-gait-features-in-older-adults-walking-on-inclined-surfaces-at-different-speeds
#4
Marcus Fraga Vieira, Fábio Barbosa Rodrigues, Gustavo Souto de Sá E Souza, Rina Márcia Magnani, Georgia Cristina Lehnen, Adriano O Andrade
This study evaluated linear and nonlinear gait features in healthy older adults walking on inclined surfaces at different speeds. Thirty-seven active older adults (experimental group) and fifty young adults (control group) walked on a treadmill at 100% and ±20% of their preferred walking speed for 4 min under horizontal (0%), upward (UP) (+8%), and downward (DOWN) (-8%) conditions. Linear gait variability was assessed using the average standard deviation of trunk acceleration between strides (VAR). Gait stability was assessed using the margin of stability (MoS)...
March 14, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28271306/fibrin-in-reproductive-tissue-engineering-a-review-on-its-application-as-a-biomaterial-for-fertility-preservation
#5
M C Chiti, M M Dolmans, J Donnez, C A Amorim
In recent years, reproductive medicine has made good use of tissue engineering and regenerative medicine techniques to develop alternatives to restore fertility in cancer patients. For young female cancer patients who cannot undergo any of the currently applied strategies due to the possible presence of malignant cells in their ovaries, the challenge is creating an in vitro or in vivo artificial ovary using carefully selected biomaterials. Thanks to its numerous qualities, fibrin has been widely used as a scaffold material for fertility preservation applications...
March 7, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28255679/computational-parametric-studies-investigating-the-global-hemodynamic-effects-of-applied-apical-torsion-for-cardiac-assist
#6
Elaine Soohoo, Lewis K Waldman, Dennis R Trumble
Healthy hearts have an inherent twisting motion that is caused by large changes in muscle fiber orientation across the myocardial wall and is believed to help lower wall stress and increase cardiac output. It was demonstrated that applied apical torsion (AAT) of the heart could potentially treat congestive heart failure (CHF) by improving hemodynamic function. We report the results of parametric computational experiments where the effects of using a torsional ventricular assist device (tVAD) to treat CHF were examined using a patient-specific bi-ventricular computational model...
March 2, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28247039/alginate-a-versatile-biomaterial-to-encapsulate-isolated-ovarian-follicles
#7
Julie Vanacker, Christiani A Amorim
In vitro culture of ovarian follicles isolated or enclosed in ovarian tissue fragments and grafting of isolated ovarian follicles represent a potential alternative to restore fertility in cancer patients who cannot undergo cryopreservation of embryos or oocytes or transplantation of frozen-thawed ovarian tissue. In this regard, respecting the three-dimensional (3D) architecture of isolated follicles is crucial to maintaining their proper follicular physiology. To this end, alginate hydrogel has been widely investigated using follicles from numerous animal species, yielding promising results...
February 28, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28243826/differentiation-of-mouse-primordial-germ-cells-into-functional-oocytes-in-vitro
#8
Kanako Morohaku, Yuji Hirao, Yayoi Obata
Various complex molecular events in oogenesis cannot be observed in vivo. As a bioengineering technique for female reproductive tissues, in vitro culture systems for female germ cells have been used to analyze oogenesis and preserve germ cells for over 20 years. Recently, we have established a new methodological approach for the culture of primordial germ cells (PGCs) and successfully obtained offspring. Our PGC culture system will be useful to clarify unresolved mechanisms of fertility and sterility from the beginning of mammalian oogenesis, before meiosis...
February 27, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28224370/a-dual-mode-bioreactor-system-for-tissue-engineered-vascular-models
#9
N Bono, S Meghezi, M Soncini, M Piola, D Mantovani, Gianfranco Beniamino Fiore
In the past decades, vascular tissue engineering has made great strides towards bringing engineered vascular tissues to the clinics and, in parallel, obtaining in-lab tools for basic research. Herein, we propose the design of a novel dual-mode bioreactor, useful for the fabrication (construct mode) and in vitro stimulation (culture mode) of collagen-based tubular constructs. Collagen-based gels laden with smooth muscle cells (SMCs) were molded directly within the bioreactor culture chamber. Based on a systematic characterization of the bioreactor culture mode, constructs were subjected to 10% cyclic strain at 0...
February 21, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28224369/proximity-of-metastatic-cells-enhances-their-mechanobiological-invasiveness
#10
Yulia Merkher, Daphne Weihs
A critical step in metastases formation is cancer-cell invasion through tissue. During invasion, cells change morphology and apply forces to their surroundings. We have previously shown that single, metastatic breast-cancer cells will mechanically indent a synthetic, impenetrable polyacrylamide gel with physiological-stiffness in attempted invasion; benign breast cells do not indent the gels. In solid tumors, e.g., breast cancers, metastases occur predominantly by collective cell-invasion. Thus, here we evaluate the effects of cell proximity on mechanical invasiveness, specifically through changes in gel indention...
February 21, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28210875/retraction-note-to-effect-of-anti-sticking-nanostructured-surface-coating-on-minimally-invasive-electrosurgical-device-in-brain
#11
Han-Yi Cheng, Keng-Liang Ou, Hsi-Jen Chiang, Li-Hsiang Lin
No abstract text is available yet for this article.
February 16, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28194660/a-novel-apparatus-for-the-multifaceted-evaluation-of-arterial-function-through-transmural-pressure-manipulation
#12
Toshiyuki Yaguchi, Yalin Cong, Kenji Shimo, Takahiro Kurokawa, Shukei Sugita, Kazuaki Nagayama, Hiroshi Masuda, Takeo Matsumoto
A novel apparatus for the multifaceted evaluation of artery function was developed. It measures endothelial and smooth muscle functions and the pressure-strain elastic modulus (E p). A rigid airtight chamber with an ultrasound probe was attached to the upper arm to manipulate the transmural pressure of the brachial artery. Endothelial function was measured via a standard flow-mediated dilation (FMD) protocol. Smooth muscle function was evaluated via a myogenic contraction of the artery following the application of negative pressure to the chamber and was named pressure-mediated contraction (PMC)...
February 13, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28194659/activity-of-erector-spinae-during-trunk-forward-bending-and-backward-return-the-effects-of-age
#13
Iman Shojaei, Babak Bazrgari
Electromyography (EMG)-based measures of the trunk muscles behavior have been used for objective assessment of biomechanical impairments in patients with low back pain (LBP); yet the literature on normal age-related differences in such measures is scant. A cross-sectional study was designed to assess age-related differences in activity of trunk extensors during forward bending and backward return. Sixty asymptomatic individuals were recruited to form five gender-balanced age groups between 20 and 70 years old...
February 13, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28194658/the-interaction-of-intramuscular-ketorolac-toradol-and-concussion-in-a-rat-model
#14
Amanda O Esquivel, Sarah S Sherman, Cynthia A Bir, Stephen E Lemos
The purpose of this study was to examine the interaction of a single dose of Toradol and head impact in an in vivo rat model for sport-related concussion using a validated rat concussion model. Thirty-five Sprague-Dawley rats were placed into one of four groups: (1) Control, (2) Impact Only, (3) Toradol Only, (4) Impact and Toradol. Animals in the impact groups were subjected to a single head impact. Animals in the Toradol group received a single intramuscular injection of Toradol prior to impact. We examined magnetic resonance imaging, serum S100-B and cognitive function using a Morris Water Maze...
February 13, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28181002/objective-assessment-of-endovascular-navigation-skills-with-force-sensing
#15
Hedyeh Rafii-Tari, Christopher J Payne, Colin Bicknell, Ka-Wai Kwok, Nicholas J W Cheshire, Celia Riga, Guang-Zhong Yang
Despite the increasing popularity of endovascular intervention in clinical practice, there remains a lack of objective and quantitative metrics for skill evaluation of endovascular techniques. Data relating to the forces exerted during endovascular procedures and the behavioral patterns of endovascular clinicians is currently limited. This research proposes two platforms for measuring tool forces applied by operators and contact forces resulting from catheter-tissue interactions, as a means of providing accurate, objective metrics of operator skill within a realistic simulation environment...
February 8, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28168380/erratum-to-restoring-fertility-with-cryopreserved-prepubertal-testicular-tissue-perspectives-with-hydrogel-encapsulation-nanotechnology-and-bioengineered-scaffolds
#16
Maxime Vermeulen, Jonathan Poels, Francesca de Michele, Anne des Rieux, Christine Wyns
No abstract text is available yet for this article.
February 6, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28168379/continuous-flow-left-ventricular-assist-device-support-improves-myocardial-supply-demand-in-chronic-heart-failure
#17
Kevin G Soucy, Carlo R Bartoli, Dustin Phillips, Guruprasad A Giridharan, Michael A Sobieski, William B Wead, Robert D Dowling, Zhongjun J Wu, Sumanth D Prabhu, Mark S Slaughter, Steven C Koenig
Continuous-flow left ventricular assist devices (CF LVADs) are rotary blood pumps that improve mean blood flow, but with potential limitations of non-physiological ventricular volume unloading and diminished vascular pulsatility. In this study, we tested the hypothesis that left ventricular unloading with increasing CF LVAD flow increases myocardial flow normalized to left ventricular work. Healthy (n = 8) and chronic ischemic heart failure (IHF, n = 7) calves were implanted with CF LVADs. Acute hemodynamics and regional myocardial blood flow were measured during baseline (LVAD off, clamped), partial (2-4 L/min) and full (>4 L/min) LVAD support...
February 6, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28160103/stents-biomechanics-biomaterials-and-insights-from-computational-modeling
#18
REVIEW
Georgia S Karanasiou, Michail I Papafaklis, Claire Conway, Lampros K Michalis, Rami Tzafriri, Elazer R Edelman, Dimitrios I Fotiadis
Coronary stents have revolutionized the treatment of coronary artery disease. Improvement in clinical outcomes requires detailed evaluation of the performance of stent biomechanics and the effectiveness as well as safety of biomaterials aiming at optimization of endovascular devices. Stents need to harmonize the hemodynamic environment and promote beneficial vessel healing processes with decreased thrombogenicity. Stent design variables and expansion properties are critical for vessel scaffolding. Drug-elution from stents, can help inhibit in-stent restenosis, but adds further complexity as drug release kinetics and coating formulations can dominate tissue responses...
February 3, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28155122/anisotropic-permeability-of-trabecular-bone-and-its-relationship-to-fabric-and-architecture-a-computational-study
#19
T C Kreipke, G L Niebur
Trabecular bone is a porous, mineralized tissue found in vertebral bodies, the metaphyses and epiphyses of long bones, and in the irregular and flat shaped bones. The pore space is filled with bone marrow, a highly cellular fluid. Together, the bone and marrow behave as a poroelastic solid. In poroelasticity theory, the permeability is the primary material property that governs the momentum transfer between the solid and fluid constituents. In the linearized theory, the permeability of a material depends on the shape and connectivity of the pores...
February 2, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28150055/numerical-modeling-of-nitinol-stent-oversizing-in-arteries-with-clinically-relevant-levels-of-peripheral-arterial-disease-the-influence-of-plaque-type-on-the-outcomes-of-endovascular-therapy
#20
Can Gökgöl, Nicolas Diehm, Philippe Büchler
Oversizing of the Nitinol stents in the femoro-popliteal arterial tract is commonly performed by clinicians and further encouraged by stent manufacturers. However, in spite of the procedure's supposed benefits of strong wall apposition and increased luminal gain, its effects on the mechanical behavior of arteries with peripheral arterial disease are not fully clear. In this study, finite element (FE) analyses of endovascular revascularization of an idealized artery with 70% stenosis and three different plaque types have been performed to examine the influence of Nitinol stent oversizing on the arterial stresses and acute lumen gain...
February 1, 2017: Annals of Biomedical Engineering
journal
journal
23089
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"