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Rhinology

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https://www.readbyqxmd.com/read/29166426/rhinology-future-debates-an-euforea-report
#1
W J Fokkens, C Bachert, M Bernal-Sprekelsen, J Bousquet, M Djandji, A Dorenbaum, D Hakimi-Mehr, S Hendry, C Hopkins, A Leunig, L Mannent, D Mucha, M Onerci, B Pugin, S Toppila-Salmi, P Rowe, S F Seys, S Stimson, A Strzembosz, P W Hellings
The first Rhinology Future Debates was held in Brussels in December 2016, organized by EUFOREA (European Forum for Research and Education in Allergy and Airways diseases). The purpose of these debates is to bring novel developments in the field of Rhinology to the attention of the medical, paramedical and patient community, in a highly credible and balanced context. For the first time in Rhinology, a peer to peer scientific exchange with key experts in the field of rhinology and key medical colleagues from leading industries let to a brainstorming and discussion event on a number of hot issues in Rhinology...
November 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29166425/anatomy-of-the-sphenopalatine-artery-and-its-implications-for-transnasal-neurosurgery
#2
M Eordogh, A Grimm, I Gawish, L Patonay, R Reisch, H R Briner, G Baksa
BACKGROUND: The knowledge of sinonasal vasculature is inevitable in transnasal neurosurgery. We performed an anatomical study on the sphenopalatine artery from the perspective of skull base procedures. METHODOLOGY: To analyse the anatomical landmarks of the sphenopalatine artery, arterial skull corrosion casts (26 head halves) underwent endoscopic transnasal phantom surgery. Furthermore, we performed microsurgical dissection on formaldehyde-fixated cadavers with arterial perfusion (14 head halves) as well as studied Cone Beam CT-scans of anonymised patients and cadavers (115 head sides)...
November 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29166424/the-future-in-rhinology-from-local-treatment-to-monoclonals-and-influencing-the-microbiome
#3
W J Fokkens
Over the last few decades, rhinology has been one of the most dynamic and progressive areas of ENT. We have not experienced such an intense period of development since the introduction of nasal corticosteroids in the 1970s.
November 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29166423/exhaled-and-nasal-nitric-oxide-in-chronic-rhinosinusitis-patients-with-nasal-polyps-in-primary-care
#4
M Frendo, K Hakansson, S Schwer, A T Ravn, H Meteran, C Porsbjerg, V Backer, C von Buchwald
BACKGROUND: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder associated with lower airway disease. However, only few studies of CRSwNP from outside secondary/tertiary care centres have been published. We recently reported an asthma frequency of 44% and 65% in primary and secondary care patients respectively. Therefore, we hypothesise that inflammation of the lower airways could be present in all CRSwNP patients, even without asthma. Here, we assessed the degree of lower and upper airway inflammation using exhaled and nasal nitric oxide (NO) in primary care CRSwNP patients with and without asthma...
November 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29166422/-unknown-title
#5
P Stokes, J Rimmer
BACKGROUND: Hereditary haemorrhagic telangiectasia (HHT) remains a difficult disease for the ENT specialist to manage. Affected patients often report recurrent epistaxis as the most debilitating symptom. The pathogenesis of the disease is due to genetic mutations affecting angiogenesis. For this reason, the anti-angiogenic therapy bevacizumab has gained popularity in the local treatment of epistaxis in patients with HHT. OBJECTIVE: A systematic review of the efficacy of bevacizumab in local treatment of epistaxis in patients with HHT based on epistaxis duration, frequency, severity and impact on quality of life...
November 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29150922/prospective-evaluation-of-a-nonsurgical-device-for-rhinoplasty
#6
M A Deggeller, D Holzmann, M B Soyka
BACKGROUND: Rhinoplasty represents one of the most challenging and frequently performed procedures in plastic surgery and non-surgical rhinoplasty is rarely considered. The aim of this study was to investigate whether the Nasella Nose Former (NNF), a newly developed non-surgical rhinoplasty device, could improve objective and subjective results following surgical rhinoplasty and even correct the shape of the nose without any surgery at all. METHODOLOGY: In this prospective, monocentric, two-armed, non-blinded randomized, controlled clinical trial, a total of 43 participants were included...
November 18, 2017: Rhinology
https://www.readbyqxmd.com/read/29069120/lateral-lamella-of-the-cribriform-plate-a-keystone-landmark-proposal-for-a-novel-classification-system
#7
R Gera, F Mozzanica, A Karligkiotis, A Preti, F Bandi, S Gallo, A Schindler, C Bulgheroni, F Ottaviani, P Castelnuovo
BACKGROUND: The aim of this study is to propose a classification of the angle formed by the lateral lamella of the cribriform plate (LLCP) and the horizontal plane passing through the cribriform plate. In particular, the angle was classified into class I (over 80 degrees), class II (45 to 80 degrees, and class III (under 45 degrees) METHODOLOGY: A total of 190 computed tomography scans were retrospectively reviewed in order to obtain four sets of measurements. 1) depth of the cribriform, 2) angle, 3) length of the LLCP, 4) width of the fovea ethmoidalis...
October 25, 2017: Rhinology
https://www.readbyqxmd.com/read/29055966/comparison-between-unilateral-pnif-and-rhinomanometry-in-the-evaluation-of-nasal-cycle
#8
A L Pendolino, E Nardello, V J Lund, P Maculan, B Scarpa, A Martini, G Ottaviano
BACKGROUND: Human unilateral nasal airflow shows spontaneous changes over a period of hours due to the alternating congestion and decongestion of the venous sinuses within the nasal turbinates and nasal septum. The aim of the present study was to compare PNIF and unilateral PNIF with nasal resistances measured by means of AAR in the evaluation of the nasal cycle. METHODS: PNIF, unilateral PNIF and AAR measurements were randomly performed in 20 non-smokers, non-asthmatic volunteers, with a SNOT 22 score lower than 1...
October 22, 2017: Rhinology
https://www.readbyqxmd.com/read/29055142/the-fate-of-the-bone-graft-in-cerebrospinal-fluid-rhinorrhea-endoscopic-repair-for-idiopathic-intracranial-hypertension-a-retrospective-case-series-analysis
#9
A D Workman, R M Carey, A K Parasher, E C Kuan, J Godovchik, J T Glicksman, D W Kennedy, J N Palmer, N D Adappa
INTRODUCTION: Idiopathic intracranial hypertension (IIH) is a common cause of spontaneous cerebrospinal fluid (CSF) leaks necessitating surgical intervention, and grafting of septal, mastoid, or turbinate bone over the defect is increasingly performed to strengthen the repair of the primary defect. However, the postoperative fate of these grafted bone fragments is largely unknown. METHODOLOGY: We performed a retrospective study of patients at the University of Pennsylvania undergoing repair of spontaneous CSF leaks secondary to IIH...
October 21, 2017: Rhinology
https://www.readbyqxmd.com/read/28988260/the-significance-of-computed-tomography-in-invasive-paranasal-mucormycosis
#10
G Slonimsky, E Slonimsky, A Yakirevitch, D Sagiv, S Duvdevani, Y P Talmi, M Wolf, E E Alon
INTRODUCTION: Early diagnosis of acute invasive fungal rhinosinusitis (AIFR) is crucial for patients prognosis and may reduce the extent of surgical debridement. Initial evaluation usually includes paranasal Computed Tomography (CT), with an emphasis on bony erosion which is considered a specific but insensitive radiologic sign. Most studies made no distinction between Aspergillus and Mucor species while addressing CT findings. In this study, we seek to evaluate whether bony erosion on paranasal CT is a significant and reliable finding in the initial evaluation of invasive paranasal mucormycosis...
October 8, 2017: Rhinology
https://www.readbyqxmd.com/read/28988259/a-straight-choice-avoiding-septal-re-deviation-using-titanium-plates-a-16-year-retrospective-patient-follow-up-evaluation
#11
J M Godoy S, J M Godoy, A Godoy, C Revelo
BACKGROUND: To propose a new surgical technique for fixing the nasal septum to the midline, for long term prevention of nasal obstruction, in secondary and select cases of primary septoplasty. METHODOLOGY: Retrospective study, within hospital medical center. PATIENTS: Two hundred and twenty two patients who underwent septoplasty. Data collection occurred consecutively between March 1st of 2000 and May 1st 2016. Twenty six percent females and seventy four percent males...
October 8, 2017: Rhinology
https://www.readbyqxmd.com/read/28988258/moving-beyond-descriptions-of-diversity-clinical-and-research-implications-of-bacterial-imbalance-in-chronic-rhinosinusitis
#12
B Wagner Mackenzie, D W Waite, M Hoggard, M W Taylor, K Biswas, R G Douglas
Chronic rhinosinusitis (CRS) is a debilitating disease which affects 5-16% of the general population and involves long-term inflammation of the sinonasal cavity. While microbial involvement in the pathogenesis of CRS has long been suspected, the exact role of microbes remains unclear. Recent application of cultivation-independent, molecular methods has provided much new information, taking advantage of developments in both laboratory- and bioinformatics-based analyses. The aim of this mini-review is to present a variety of available bioinformatics approaches, such as data classification techniques and network analyses, with proven applications in other aspects of human microbiome health and disease research...
October 8, 2017: Rhinology
https://www.readbyqxmd.com/read/28942457/mp-azeflu-provides-rapid-and-effective-allergic-rhinitis-control-results-of-a-non-interventional-study-in-romania
#13
I Agache, I C Doros, P M Leru, I Bucur, M Poenaru, C Sarafoleanu
BACKGROUND: Allergic Rhinitis and its Impact on Asthma (ARIA) and the European Union (EU) recommend a shift to guide allergic rhinitis (AR) treatment decisions from symptom severity to disease control, using a simple visual analogue scale (VAS). Using this VAS we assessed, in a real-life study in Romania, the effectiveness of MP-AzeFlu nasal spray. METHODOLOGY: In this multi-centre, prospective, non-interventional study, 253 patients (over 11 years old) with moderate-to-severe AR were prescribed MP-AzeFlu and assessed their symptoms on a VAS (0 (not at all bothersome) to 100 mm (very bothersome)) on Days 0, 1, 3, 7 and 14...
October 6, 2017: Rhinology
https://www.readbyqxmd.com/read/28888026/regional-recurrence-in-a-case-series-of-patients-with-carcinoma-of-the-nasal-cavity-therapeutic-implications
#14
T Hussain, S Mattheis, N Dominas, B Hoing, S Lang, B A Stuck
INTRODUCTION: Surgery is the primary treatment option for squamous cell carcinomas of the nasal cavity (NCSCC). Nodal involvement is rare at the time of initial diagnosis, and the role of diagnostic neck dissection as well as potential adjuvant irradiation of the neck remains controversial. The objective of this study was to assess the oncologic outcomes of patients with NCSCC with special emphasis on cervical lymph node treatment and recurrence. METHODS: 37 previously untreated patients were included in this study...
October 1, 2017: Rhinology
https://www.readbyqxmd.com/read/28888025/comparison-of-different-endoscopic-scoring-systems-in-patients-with-chronic-rhinosinusitis-reliability-validity-responsiveness-and-correlation
#15
L Zhang, L H Zhang
OBJECTIVES: Previous studies have proposed various endoscopic scoring systems to assess disease severity of patients with chronic rhinosinusitis (CRS). However, those assessments have not been validated. This study was designed to assess the Modified Lund - Kennedy (MLK) and the discharge, inflammation, and polyps/oedema (DIP) endoscopic scoring systems in patients with CRS. METHODS: A prospective study including 144 patients who underwent functional endoscopic sinus surgery (FESS)...
September 9, 2017: Rhinology
https://www.readbyqxmd.com/read/28888024/airflow-and-symptom-outcomes-between-allergic-and-non-allergic-rhinitis-patients-from-turbinoplasty
#16
K Parthasarathi, J M Christensen, R Alvarado, H P Barham, R Sacks, R J Harvey
BACKGROUND: Inferior turbinate procedures are applied to relieve medically refractory nasal obstruction. However, the nature of congestion differs between allergic(AR) and non-allergic rhinitis(NAR). This study compares surgical outcomes between AR and NAR patients. METHODOLOGY: A case-control study of patients undergoing turbinate with or without septoplasty surgery for nasal obstruction was performed. Patient reported outcomes were: nasal obstruction, global nasal function(GNF), and sino-nasal outcome test(SNOT-22) with rhinitis, facial symptom, sleep and psychological sub-scores...
September 9, 2017: Rhinology
https://www.readbyqxmd.com/read/28887880/allergy-rhinitis-similarities-and-differences-between-children-and-adults
#17
A Izquierdo-Dominguez, I Jauregui, A Del Cuvillo, J Montoro, I Davila, J Sastre, J Bartra, M Ferrer, I Alobid, J Mullol, A L Valero
BACKGROUND: Allergic rhinitis (AR) is a highly prevalent disease worldwide. Although a number of studies have described AR, no studies compared children and adult AR populations. The objective was to compare the AR characteristics between two AR cohorts of children and adults. METHODS: Two AR cohorts (children and adults) from Spain were studied through observational cross-sectional multicentre studies. AR was classified based on classical (allergen exposure), original (o-ARIA), and modified (m-ARIA) ARIA criteria...
September 9, 2017: Rhinology
https://www.readbyqxmd.com/read/28887879/orbital-floor-fracture-repair-the-endonasal-approach
#18
T Kuhnel, H Jagle, W Hosemann, R Weber, V Vielsmeier
To avoid the dangers associated with lower eyelid approaches to the orbital floor and to improve visualization, we propose an endoscopic procedure for orbital floor fracture reduction and osteosynthesis using endonasal access via the medial maxillary sinus wall. The technique of endoscopic, endonasal transantral surgery is described, together with a retrospective analysis of 17 patients who had undergone this surgical procedure in the Department of Otorhinolaryngology, University of Regensburg, between July 2013 and June 2016...
September 9, 2017: Rhinology
https://www.readbyqxmd.com/read/28865140/the-comparison-of-nasal-surgery-and-cpap-on-daytime-sleepiness-in-patients-with-osas
#19
M Tagaya, H Otake, K Suzuki, F Yasuma, H Yamamoto, A Noda, Y Nishimura, M Sone, T Nakashima, S Nakata
OBJECTIVE: Residual sleepiness after continuous positive airway pressure (CPAP) is a critical problem in some patients with obstructive sleep apnea syndrome (OSAS). However, nasal surgery is likely to reduce daytime sleepiness and feelings of unrefreshed sleep. The aim of this study is to clarify the effects of nasal surgery and CPAP on daytime sleepiness. METHODOLOGY: This is a retrospective and matched-case control study. The participants were consecutive 40 patients with OSAS who underwent nasal surgery (Surgery group) and 40 matched patients who were treated with CPAP (CPAP group)...
September 1, 2017: Rhinology
https://www.readbyqxmd.com/read/28865115/paving-the-future-of-rhinosinusitis-care
#20
P W Hellings
Novel insights into the pathophysiology of chronic rhinosinsusitis (CRS) will lead to endo-type driven treatment and reduce oral corticosteroid treatment.
September 1, 2017: Rhinology
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