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Journal of International Medical Research

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https://www.readbyqxmd.com/read/28173723/the-impact-of-complications-on-prolonged-length-of-hospital-stay-after-resection-in-colorectal-cancer-a-retrospective-study-of-taiwanese-patients
#1
Herng-Chia Chiu, Yi-Chieh Lin, Hui-Min Hsieh, Hsin-Pao Chen, Hui-Li Wang, Jaw-Yuan Wang
Objectives To assess the impact of minor, major and individual complications on prolonged length of hospital stay in patients with colorectal cancer (CRC) after surgery using multivariate models. Methods This was a retrospective review of data from patients who underwent surgery for stage I-III CRC at two medical centres in southern Taiwan between 2005-2010. Information was derived from four databases. Multivariate logistic regression methods were used to assess the impact of complications on prolonged length of stay (PLOS) and prolonged postoperative length of stay (PPOLOS)...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28173722/effect-of-a-low-frequency-pulsed-electromagnetic-field-on-expression-and-secretion-of-il-1%C3%AE-and-tnf-%C3%AE-in-nucleus-pulposus-cells
#2
Jun Zou, Yufeng Chen, Jiale Qian, Huilin Yang
Objective To investigate changes in nucleus pulposus cell expression and secretion of interleukin (IL)-1β and tumour necrosis factor (TNF)-α following stimulation with a low-frequency (LF) pulsed electromagnetic field (PEMF). Methods Primary rat nucleus pulposus cells were isolated and cultured in vitro, followed by stimulation with LF-PEMFs at a frequency of 2 Hz and different intensities, ranging from 0.5-3.0 A/m. Cells were observed for morphological changes, and proliferation rates were measured by cell viability counts...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28173721/rosai-dorfman-disease-of-the-subdural-spine-with-a-long-segment-lesion-a-case-report-and-literature-review
#3
Ji Tu, Wen-Tian Li, Cao Yang
Rosai-Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy is a rare benign disorder usually characterized by massive painless cervical lymphadenopathy and systemic manifestations. Extranodal involvement, especially spinal involvement, is extremely rare. We report a 41-year-old man who presented with only intermittent dorsodynia. His condition was diagnosed as non-specific inflammatory disease on the basis of preoperative puncture biopsy results. We performed total surgical resection. Histopathological findings showed distinctive emperipolesis and immunohistochemistry results were positive for cluster of differentiation CD68 and S100 and negative for CD1a...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28173712/incidence-and-risk-factors-of-postoperative-sore-throat-after-endotracheal-intubation-in-korean-patients
#4
Jin Young Lee, Woo Seog Sim, Eun Sung Kim, Sangmin M Lee, Duk Kyung Kim, Yu Ri Na, Dahye Park, Hue Jung Park
Objective To investigate the incidence of postoperative sore throat (POST) in Korean patients undergoing general anaesthesia with endotracheal intubation and to assess potential risk factors. Methods This prospective study enrolled patients who underwent all types of elective surgical procedures with endotracheal intubation and general anaesthesia. The patients were categorized into group S (those with a POST) or group N (those without a POST). The demographic, clinical and anaesthetic characteristics of each group were compared...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28173711/association-between-patency-of-the-circle-of-willis-and-diabetes-mellitus-in-patients-with-cerebral-ischaemic-stroke
#5
Ying Chi, Zu-Neng Lu
Objective To examine patency of the cerebral anterior and posterior communicating arteries in patients with ischaemic stroke with or without diabetes mellitus. Methods This retrospective study included patients with acute ischaemic stroke treated between July 2011 and May 2016. Cerebral infarction was evaluated by magnetic resonance imaging. Anterior and posterior communicating-artery patency was determined using magnetic resonance angiography. Vessels were defined as patent or occluded. Results Out of 1 406 patients, incidence of vertebral basilar artery brain infarction and posterior cerebral artery brain infarction were significantly higher in patients with diabetes versus those without diabetes (35...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/27913747/clinicopathological-significance-of-oestrogen-receptor-expression-in-non-small-cell-lung-cancer
#6
Xiang-Qi Chen, Li-Xian Zheng, Zhi-Ying Li, Ting-Yan Lin
OBJECTIVE: To investigate the expression and clinicopathological significance of the oestrogen receptor (ER) in non-small cell lung cancer (NSCLC). METHODS: ER expression was examined by immunohistochemical staining of tumour tissue and adjacent normal lung tissue from 67 NSCLC patients. The relationships between ER expression and clinicopathological features were analysed. RESULTS: A higher percentage of NSCLC tissues (28/67, 41.79%) than adjacent normal lung tissues (10/55, 18...
December 2, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27913746/anti-trachea-inflammatory-effects-of-diosgenin-from-dioscorea-nipponica-through-interactions-with-glucocorticoid-receptor-%C3%AE
#7
Yang Junchao, Wang Zhen, Wang Yuan, Xu Liying, Jiang Libin, Zhu Yuanhong, Zhao Wei, Chen Ruilin, Zhai Lu
Asthma is a heterogeneous disease characterized by symptoms of chronic inflammation and airway structural and functional changes. It affects about 300 million people worldwide and causes 250 000 deaths annually, but its symptoms can be greatly relieved by regular use of inhaled glucocorticoids (GCs). GCs exert their function through interacting with glucocorticoid receptors (GRs). Diosgenin is a naturally occurring steroidal saponin abundantly present in many medicinal plants, including Dioscorea nipponica, which shares a similar steroidal structure with GC...
December 2, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27913745/the-association-of-uric-acid-with-leukoaraiosis
#8
Jun-Jing Li, Yin-Hui Huang, You-Yu Lin, Mi-Mi Li, Ya-Fang Chen, Ruo-Wei Cai
OBJECTIVE: To explore the possible correlation between uric acid levels and leukoaraiosis (LA). METHODS: This cross-sectional study enrolled patients who presented with some neurological discomfort (e.g. dizziness, headache, mild cognitive impairment). Potential demographic and clinical risk factors associated with LA, including sex, age, hypertension, diabetes mellitus, smoking, alcohol consumption, dyslipidaemia, plasma fibrinogen, D-dimer, uric acid, and homocysteine, were investigated using univariate and multivariate logistic regression analyses...
December 2, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27913744/effects-of-atorvastatin-on-adp-arachidonic-acid-collagen-and-epinephrine-induced-platelet-aggregation
#9
Lei Zhao, Demin Liu, Bin Liu, Haijuan Hu, Wei Cui
OBJECTIVE: Atorvastatin reduces the incidence of cardiovascular events. However, the effects of atorvastatin on platelet aggregation are unknown. METHODS: Blood samples were obtained from 126 healthy volunteers. Prepared isolated platelet suspensions were adjusted with saline to three different concentrations of 100 × 10(9), 300 × 10(9), and 600 × 10(9) platelets/L. Platelet samples were incubated with atorvastatin (10(-7 )mol/L, 10(-6 )mol/L or 10(-5 )mol/L), and stimulated with ADP (10 µmol/L), arachidonic acid (0...
December 2, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/27913743/effect-of-dexmedetomidine-on-postoperative-cognitive-dysfunction-in-elderly-patients-after-general-anaesthesia-a-meta-analysis
#10
Chengmao Zhou, Yu Zhu, Zhen Liu, Lin Ruan
OBJECTIVE: We undertook a meta-analysis to investigate the effect of dexmedetomidine on postoperative cognitive dysfunction (POCD). METHODS: We searched PubMed, EMBASE, the Cochrane Library, CNKI and Google Scholar to find randomized controlled trials (RCTs) of the influence of dexmedetomidine on POCD in elderly adults who had undergone general anaesthesia. Two researchers independently screened the literature, extracted data, and evaluated methodologic quality against inclusion and exclusion criteria...
December 2, 2016: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222648/autologous-stem-cell-transplantation-as-frontline-strategy-for-peripheral-t-cell-lymphoma-a-single-centre-experience
#11
Xiao Han, Wei Zhang, Daobin Zhou, Jing Ruan, Minghui Duan, Tienan Zhu, Jian Li, Huacong Cai, Xinxin Cao, Mingqi Ouyang
Objective To determine the efficacy and prognosis of autologous hematopoietic stem cell transplantation (ASCT) as frontline treatment for peripheral T cell lymphoma (PTCL). Methods Clinical data from 46 PTCL patients who achieved complete (CR) or partial remission (PR) after ASCT from October 1996 to July 2014 were analysed retrospectively. Results Median patient age was 32 (range: 15-68) years. Disease types included PTCL, unspecified type, in 23 patients, anaplastic large cell lymphoma in eight, angioimmunoblastic lymphoma in eight, extranodal NK/T-cell lymphoma in five, and hepatosplenic T-cell lymphoma and enteropathy associated T-cell lymphoma in one each...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222647/medication-literacy-status-of-outpatients-in-ambulatory-care-settings-in-changsha-china
#12
Feng Zheng, Siqing Ding, Aijing Luo, Zhuqing Zhong, Yinglong Duan, Zhiying Shen
Objective To assess medication literacy status and to examine risk factors of inadequate medication literacy of outpatients in ambulatory care settings. Methods Study participants were recruited randomly from outpatient departments in four tertiary hospitals (Xiangya Hospital of Central South University, Second Xiangya Hospital of Central South University, Third Xiangya Hospital of Central South University, People's Hospital of Hunan Province) in Changsha, Hunan, China, between October 2014 and January 2015...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222646/effectiveness-of-contrast-enhanced-ultrasound-and-serum-liver-enzyme-measurement-in-detection-and-classification-of-blunt-liver-trauma
#13
Da-Wei Zhao, Meng Tian, Le-Tian Zhang, Tao Li, Jie Bi, Jia-Ying He, Ying-Ying Zhang
Objective This study was performed to identify the correlation between contrast-enhanced ultrasound (CEUS) and contrast-enhanced multidetector computed tomography (CE-MDCT) as well as the correlation between serum liver enzyme concentrations and CE-MDCT in classification of the severity of blunt hepatic trauma using CE-MDCT as a reference standard. Materials and methods A blunt liver trauma model was created using 20 rabbits, and CE-MDCT, CEUS, and serum liver enzyme assays were performed. A radiologist and an ultrasound physician independently evaluated the degree of liver trauma...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222645/total-intravenous-anesthesia-produces-outcomes-superior-to-those-with-combined-intravenous-inhalation-anesthesia-for-laparoscopic-gynecological-surgery-at-high-altitude
#14
Rui Xu, Shuqin Zhou, Jin Yang, Haiyan Li, Qingguo Zhang, Guohong Zhang, Shiyuan Xu, Qing Peng
Objective We compared efficacy and adverse outcomes following totally intravenous anesthesia (TIVA) versus combined intravenous-inhalation anesthesia (CIVIA) on hemodynamics and postoperative recovery following laparoscopic gynecological (LG) surgery at high altitudes. Methods We enrolled 80 ASA I or II patients scheduled for LG surgery and randomly assigned them to TIVA with propofol (group P, n = 40) or CIVIA with isoflurane (group I, n = 40). Mean arterial pressure, heart rate, pulse oxygen saturation, and partial pressure of end-tidal carbon dioxide were measured at various time points...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222644/use-of-the-injection-test-to-indicate-the-oesophageal-balloon-position-in-patients-without-spontaneous-breathing-a-clinical-feasibility-study
#15
Han Chen, Yan-Lin Yang, Ming Xu, Zhong-Hua Shi, Xuan He, Xiu-Mei Sun, Xu-Ying Luo, Guang-Qiang Chen, Jian-Xin Zhou
Objective To investigate the clinical feasibility of the injection test for balloon placement during oesophageal pressure measurement in patients without spontaneous breathing. Methods The injection test was performed in 12 mechanically ventilated patients under deep sedation and paralysis. During withdrawal of the balloon from the stomach and air injection into the gastric lumen of the catheter, the presence of the injection test wave in the balloon pressure tracing indicated that the whole balloon was positioned above the lower oesophageal sphincter (LES)...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222643/reliability-of-home-based-motor-function-measure-in-hereditary-neuromuscular-diseases
#16
Xiomara Ruiz-Cortes, Fernando Ortiz-Corredor, Camilo Mendoza-Pulido
Objective To evaluate the reliability of the motor function measure (MFM) scale in the assessment of disease severity and progression when administered at home and clinic and assess its correlation with the Paediatric Outcomes Data Collection Instrument (PODCI). Methods In this prospective study, two assessors rated children with hereditary neuromuscular diseases (HNMDs) using the MFM at the clinic and then 2 weeks later at the patients' home. Intraclass correlation coefficient (ICC) was calculated for the reliability of the MFM and its domains...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222642/prediction-of-intraoperative-nausea-and-vomiting-in-caesarean-delivery-under-regional-anaesthesia
#17
Altuğ Semiz, Yaşam Kemal Akpak, Necip Cihangir Yılanlıoğlu, Ali Babacan, Gökhan Gönen, Canan Çam Gönen, Murat Asıliskender, Selim Karaküçük
Objectives This study aimed to predict patients who have caesarean operations under regional anaesthesia and are at risk for intraoperative nausea and vomiting (IONV), for ultimately prompting anaesthetists and surgeons to take preventive measures. Methods This was a retrospective study on 209 patients who had caesarean section under spinal-epidural combined regional anaesthesia. The relevant medical history, such as severe nausea and vomiting in the first trimester, smoking, a history of motion sickness, and premenstrual syndrome (PMS), were obtained from the patients' records and interviews...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222641/genotyping-guided-approach-versus-the-conventional-approach-in-selection-of-oral-p2y12-receptor-blockers-in-chinese-patients-suffering-from-acute-coronary-syndrome
#18
Chor Cheung Tam, Janette Kwok, Anthony Wong, Arthur Yung, Catherine Shea, Shun Ling Kong, Wing Hong Tang, David Siu, Raymond Chan, Stephen Lee
Objective The CYP2C19 loss-of-function (LoF) allele is present in half of the East Asian population and is associated with high on-treatment platelet reactivity (HTPR). This study aimed to investigate whether a rapid genotyping-guided approach is feasible and efficacious for selecting P2Y12 receptor blockers in Chinese patients suffering from acute coronary syndrome (ACS). Methods This was a single-centre, prospective, randomized, open-label study. A total of 132 patients with ACS were randomized to the rapid genotyping-guided treatment group (GG, N = 65) or the standard treatment group (SG, N = 67)...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222640/dynamic-long-leg-casting-fixation-for-treating-12-to-18-month-old-infants-with-developmental-dysplasia-of-the-hip
#19
Zhencun Cai, Lianyong Li, Lijun Zhang, Shijun Ji, Qun Zhao
Objective To evaluate the effect of dynamic long leg casting in paediatric patients with developmental dysplasia of hip (DDH) diagnosed at 12-18 months. Methods The adductor tenotomy, closed reduction, and dynamic long leg casting method was adopted to treat paediatric patients with DDH. The hips were divided into four groups according to the Tonnis radiographic dislocation classification. Groups were also classified according to the baseline acetabular index (AI): 30°-35°, 36°-40°, and > 40°. The outcomes of the reductions were evaluated according to McKay's hip function criteria and Severin's radiological criteria...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222639/biomechanical-characteristics-of-skeletal-muscles-and-associations-between-running-speed-and-contraction-time-in-8-to-13-year-old-children
#20
Jernej Završnik, Rado Pišot, Boštjan Šimunič, Peter Kokol, Helena Blažun Vošner
Objective To investigate associations between running speeds and contraction times in 8- to 13-year-old children. Method This longitudinal study analyzed tensiomyographic measurements of vastus lateralis and biceps femoris muscles' contraction times and maximum running speeds in 107 children (53 boys, 54 girls). Data were evaluated using multiple correspondence analysis. Results A gender difference existed between the vastus lateralis contraction times and running speeds. The running speed was less dependent on vastus lateralis contraction times in boys than in girls...
February 2017: Journal of International Medical Research
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