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ORL; Journal for Oto-rhino-laryngology and its related Specialties

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https://www.readbyqxmd.com/read/27880959/morphology-and-ciliary-motion-of-the-middle-ear-mucosa-of-neonatal-and-adult-gerbils
#1
Jun Li, Huizhan Liu, Nancy T He, Na Shen, Yi Li
BACKGROUND/AIMS: Since the middle ear cavity plays an important role in middle ear effusion, the goal of this study is to examine the morphological and functional development of the middle ear mucosa in neonatal and adult gerbils. METHODS: Gerbils aged between postnatal day 1 (P1) and P26 were used for the experiments. The morphological development of the middle ear cavity was measured by using the celloidin embedding method and scanning electronic microscope. Ciliary motion was determined and calibrated by a photodiode-based measurement system...
November 24, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27846635/multilayered-closure-of-cerebrospinal-fluid-rhinorrhea-with-inlay-fascia-lata-autologous-fat-and-outlay-fascia-lata-our-experience
#2
Mehmet Akif Eryılmaz, Mitat Arıcıgil, Mehmet Akif Alan
BACKGROUND/AIMS: Since the initial use in 1981 by Wigand, different endoscopic endonasal surgery techniques have been proposed to close ventral skull base defects, all of which include multilayer closure involving vascularized mucoseptal flaps, autologous grafts, and synthetic materials. These methods are used individually or in combination, as required by the operative condition. METHODS: In this study we aimed to describe our endoscopic technique using inlay-outlay fascia lata and autologous fat with fibrin sealant to close spontaneous and traumatic cerebrospinal fluid (CSF) rhinorrhea...
November 16, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27838694/hearing-restoration-for-adults-with-vestibular-schwannoma-in-the-only-hearing-ear-ipsilateral-or-contralateral-cochlear-implantation
#3
Zirong Huo, Zhihua Zhang, Qi Huang, Jun Yang, Zhaoyan Wang, Yun Li, Meiping Huang, Hao Wu
OBJECTIVE: To explore auditory outcomes following cochlear implantation (CI) in patients with vestibular schwannoma (VS) in the only hearing ear. METHODS: Three patients, all with a long history of hearing loss on one side and with newly diagnosed VS on the other side, underwent ipsilateral or contralateral CI. Their clinical data were collected retrospectively. Postoperative hearing outcomes were measured during follow-up and compared with the preoperative test results...
November 12, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27710955/morphological-variation-of-subarcuate-artery-and-canal-in-atresia
#4
Keguang Chen, Huiying Lyu, Lin Yang, Tianyu Zhang, Peidong Dai
OBJECTIVES: An aberrant subarcuate artery (SAA) and its related canal are infrequent and asymptomatic. The presence of this variation may cause untoward hemorrhages, if accidentally nicked. Therefore, it is important for otologists to be aware of this entity, and its relative anatomy, to avoid any unexpected complication. We present a case of a 7-year-old girl who presented with right-sided microtia with membranous atresia. METHODS: High-resolution computed tomographic scan and three-dimensional reconstruction of the temporal bone showed bilateral enlarged SAA...
October 7, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27658122/expression-of-dopamine-receptor-1a-and-cannabinoid-receptor-1-genes-in-the-cochlea-and-brain-after-salicylate-induced-tinnitus
#5
Juen-Haur Hwang, Yin-Ching Chan
The purpose of this study was to investigate the mRNA expression of the dopamine receptor 1A (DR1A) and cannabinoid receptor 1 (CR1) genes in mice with tinnitus. Sixteen 3-month-old male SAMP8 mice were randomly and equally divided into two groups (8 mice in each group): a control (saline-treated) group and a tinnitus (salicylate-treated) group. The mRNA expression of the DR1A and CR1 genes in the cochleae and brains of the mice was evaluated after tinnitus had been induced by intraperitoneal injection of sodium salicylate (300 mg/kg body weight)...
September 23, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27614443/quantitative-assessment-of-surgical-anatomy-and-three-dimensional-relationships-in-the-supralabyrinthine-space
#6
Yusu Ni, Kaishi Wang, Yi Jiang, Ren Zhou, Yan Sha, Huawei Li
OBJECTIVE: To explore and quantify the surgically relevant anatomic relationships and three-dimensional (3D) morphology of the supralabyrinthine space, and enable a deeper, clearer understanding of its regional anatomy. MATERIALS AND METHODS: 3D-DOCTOR software was used to create a 3D reconstruction of the axial CT images and multiplanar reformatting of 55 slices of temporal bone in 29 patients (17 males and 12 females), whose average age was 38.69 ± 17.81 years...
September 10, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27560953/submucosal-abscess-of-the-esophagus-caused-by-piriform-sinus-fistula-treated-with-transoral-video-laryngoscopic-surgery
#7
Satoshi Koyama, Kazunori Fujiwara, Tsuyoshi Morisaki, Takahiro Fukuhara, Katsuyuki Kawamoto, Hiroya Kitano, Hiromi Takeuchi
Piriform sinus fistula (PSF) is a rare branchial anomaly that causes repetitive acute suppurative thyroiditis or deep neck abscess. The definitive treatment of PSF is open neck surgery. However, such surgery has a cosmetic problem and a high risk of recurrence. Furthermore, identifying the fistula is difficult due to previous repetitive infections. We report a case of esophageal submucosal abscess caused by PSF treated with endoscopic mucosal incision. The patient underwent transoral video laryngoscopic surgery (TOVS), and endoscopy as well as fluoroscopy revealed complete closure of PSF without any complication...
August 25, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27486666/nd-yag-laser-treatment-for-extranasal-telangiectasias-a-retrospective-analysis-of-38-patients-with-hereditary-hemorrhagic-telangiectasia-and-review-of-the-literature
#8
Giorgos Papaspyrou, Bernhard Schick, Basel Al Kadah
BACKGROUND/AIMS: Extranasal telangiectasias are common amongst hereditary hemorrhagic telangiectasia (HHT) patients. Telangiectasias can be found at sites like the external nose, lips, oral cavity and fingers. Although not life threatening, they can be annoying for patients and lead to bleeding in some cases, necessitating treatment. METHODS: The data of 38 HHT patients treated for extranasal telangiectasias during a period of 10 years by means of Nd:YAG laser were retrospectively analyzed...
August 4, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27458726/what-are-the-optimal-monitoring-techniques-in-head-and-neck-microvascular-reconstruction
#9
Sami P Moubayed, Moustafa Mourad, Mark L Urken
PURPOSE: We evaluated the outcomes for widely used systems in terms of accuracy, salvage rates, and added cost compared to conventional monitoring. METHODS: We performed a narrative review of the literature (high-impact report). RESULTS: The overall free flap success for head and neck reconstruction is at least 95% using any type of monitoring. Salvage rates in decreasing frequency of monitoring techniques are 85% with near-infrared spectroscopy (NIRS), 81% with implantable Doppler, and 61...
July 27, 2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27438263/clinical-study-of-1-515-patients-presenting-with-epistaxis-over-the-last-6-years
#10
Yoriko Yukitatsu, Kenzo Tsuzuki, Hironori Takebayashi, Masafumi Sakagami
AIM: This study reviews our clinical experience of patients with epistaxis and discusses proper management. PATIENTS AND METHODS: We retrospectively investigated 1,515 patients with epistaxis treated in our department between 2005 and 2010. RESULTS: Men over 50 years old predominated. More than half of the patients (n = 828) first visited after consultation hours, and 40% (n = 606) were brought by ambulance. The most common underlying diseases were circulatory diseases (69%, n = 1,047)...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27427936/bacteriology-of-the-middle-meatus-in-chronic-rhinosinusitis-with-and-without-polyposis
#11
Sagit Stern, Tuvia Hadar, Yuval Nachalon, Haim Ben-Zvi, Ethan Soudry, Eitan Yaniv
There are only limited data in the literature, and none specifically from the Middle East, on the pathogenic bacteria in chronic rhinosinusitis (CRS) as opposed to healthy nasal cavities and their association with disease severity. The present study was conducted in the department of head and neck surgery of a tertiary medical center. Middle meatal swabs were taken preoperatively from patients with CRS with nasal polyposis (CRSwNP) (n = 60), CRS without nasal polyposis (CRSsNP) (n = 50), and control patients with septal deviation (n = 26) or no nasal abnormalities (n = 27)...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27383647/benefit-of-preoperative-oral-steroids-during-sinus-surgery-when-utilizing-concentrated-topical-epinephrine
#12
Hakan Korkmaz, William Yao, Mukadder Korkmaz, Benjamin S Bleier
BACKGROUND/AIMS: Oral steroids have been advocated in the preoperative setting as a means of reducing intraoperative blood loss and surgical time during sinus surgery. The purpose of this study was to analyze the impact of preoperative oral steroid administration on intraoperative bleeding and surgical duration when coupled with concentrated topical epinephrine. METHODS: The medical records of 302 patients who underwent bilateral 'full house' sinus surgery were reviewed...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27383538/reconstruction-of-hypopharyngeal-and-esophageal-defects-using-a-gastric-tube-after-total-esophagectomy-and-pharyngolaryngectomy
#13
Jifeng Liu, Tiehong Deng, Chao Li, Lin Peng, Qiang Li, Guiquan Zhu, Wei Wang, Yongcong Cai, Xiaojiao Lan, Yuxin He, Zhaohui Wang, Shaoxin Wang
AIM: This study investigated the value of gastric tube during surgery for advanced hypopharyngeal and cervical esophageal cancer. METHOD: From November 2007 to December 2012, 42 patients underwent total pharyngo-laryngo-esophagectomy because of advanced hypopharyngeal or cervical esophageal cancer and were reconstructed with a gastric tube. Clinical swallowing function, morbidity, overall survival, and progression-free survival were evaluated postoperatively. RESULT: There were no severe complications, including no gastric necrosis, surgery-related postoperative morbidity, hemothorax, thoracostomach, or severe reflux esophagitis...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27383429/natural-killer-cell-deficits-aggravate-allergic-rhinosinusitis-in-a-murine-model
#14
Ji Heui Kim, Chang-Hoong Gong, Go Eun Choi, Sun A Kim, Hun Sik Kim, Yong Ju Jang
OBJECTIVE: Defective innate immune functions can contribute to chronic rhinosinusitis (RS). Recently, it has been reported that chronic RS patients show impaired function of natural killer (NK) cells. We investigated the role of NK cells in eosinophilic inflammation in an allergic RS mouse model. METHODS: Mice sensitized to ovalbumin (OVA) by intraperitoneal injection received nasal challenges with OVA for 5 weeks. NK cell depletion was achieved by intraperitoneal injections of anti-asialo ganglio-N-tetraosylceramide (ASGM1) antibodies 10 days before OVA sensitization and every 5 days thereafter until sacrifice...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27383280/contemporary-neuroradiographic-assessment-of-the-cochleo-carotid-partition
#15
Nael M Shoman, Ravi N Samy, Myles L Pensak
PURPOSE: The cochleo-carotid partition (CCP) describes the intimate anatomic relationship between the petrous carotid artery and the cochlear basal turn. This partition bears significant surgical and unique clinical relevance. The purpose of this paper is to radiographically assess the CCP and discuss its clinical implications. METHODS: A total of 155 consecutive fine-cut temporal bone CT scans were retrospectively reviewed, and study scans were digitally analyzed in both axial and coronal views...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27270919/in-office-hyaluronate-injection-laryngoplasty-as-palliative-treatment-for-unilateral-vocal-fold-paralysis
#16
Ronaldo G Soriano, Yu-Chen Pei, Tuan-Jen Fang
BACKGROUND: Voice and swallowing impairments can impact on both quality of life and survival. Unilateral vocal fold paralysis (UVFP) as a result of distant metastasis can cause breathy voice and aspiration. The purpose of this study is to develop and evaluate a less invasive and effective alternative therapy for UVFP. METHODS: This was a retrospective review of prospectively enrolled patients at a tertiary referral center in Taiwan. Among a cohort of 177 patients who received intracordal hyaluronate injections, 2 had UVFP from distant metastasis and met the inclusion criteria...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27270730/low-but-not-high-doses-of-cisplatin-damage-cochlear-hair-cells-in-c57-mouse-organotypic-cultures
#17
Shan Zeng, Xiaoqiang Sun, Zhengnong Chen, Dongzhen Yu, Bin Chen, Shankai Yin
AIMS: The purpose of this study was to investigate the characteristics of cisplatin-induced C57 mouse cochlear hair cell damage in vitro. METHODS: Forty-seven cochleae harvested from 2- to 4-day-old C57 mice were used. Forty specimens were treated with different concentrations of cisplatin (10, 25, 50, 100, 400, and 1,000 μmol/l) for 48 h. The remaining seven specimens were used as a control group. RESULTS: The rate of hair cell loss increased from 14...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27256349/total-thyroidectomy-versus-bilateral-subtotal-thyroidectomy-for-bilateral-multinodular-nontoxic-goiter-a-meta-analysis
#18
Yujie Li, Yangjun Li, Xiaodong Zhou
AIM: The aim of this meta-analysis is to assess and validate the feasibility and safety of total thyroidectomy (TT) when compared to bilateral subtotal thyroidectomy (BST) for bilateral multinodular nontoxic goiter (BMNG). MATERIALS AND METHODS: PubMed, Web of Knowledge, and Ovid's database were searched for studies published in English language between January 1990 and December 2014. A meta-analysis was performed to compare the complications and recurrences of TT versus BST...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27245783/tinnitus-evaluation-of-intratympanic-injection-of-combined-lidocaine-and-corticosteroids
#19
Saad Elzayat, Hossam El-Sherif, Hassan Hegazy, Takwa Gabr, Abdel-Rahman El-Tahan
BACKGROUND: Tinnitus is an annoying problem and until now there is no consensus on its treatment. AIMS: In this prospective study, we evaluated the effectiveness of intratympanic lidocaine and dexamethasone (ITLD) injections for the management of subjective idiopathic tinnitus (SIT). METHODS: Forty patients with SIT attended the Department of Otorhinolaryngology, Tanta University Hospital, Egypt, between May 2013 and May 2014. The patients were categorized into two groups: group A included 20 patients treated with ITLD injection, and group B included 20 patients treated with intratympanic saline injection as a control...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/27234613/short-term-dynamic-observation-of-the-color-change-and-enhancement-effect-of-polyethylenimine-entrapped-gold-nanoparticles-used-for-indirect-lymphography
#20
Yue Yang, Fang Shi, Jian Zhou, Xiangyang Shi, Yan Sha, Haitao Wu
AIMS: To dynamically observe the color change and enhancement effect of gadolinium-loaded polyethylenimine-entrapped gold nanoparticles (Gd-Au PENPs) as a dual-mode CT/MRI contrast agent for sentinel lymph node (SLN) identification. METHODS: In 6 rabbits, Gd-Au PENPs were injected into the right side tongue submucosa, after which the color change of cervical draining lymph nodes was observed. Then the draining lymph nodes were examined by CT/MRI scan. Another 6 rabbits were randomly divided into a CT lymphography (CT-LG) and a MRI lymphography (MRI-LG) group and examined by CT/MRI scan 1 and 30 min after injection...
2016: ORL; Journal for Oto-rhino-laryngology and its related Specialties
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