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ORL; Journal for Oto-rhino-laryngology and its related Specialties

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https://www.readbyqxmd.com/read/30308497/nasal-symptom-questionnaire-our-proposed-scoring-system-and-prognostic-factors-in-chronic-rhinosinusitis
#1
Takahiro Saito, Kenzo Tsuzuki, Hiroki Nishikawa, Ken Okazaki, Kengo Hashimoto, Masafumi Sakagami
OBJECTIVES: We aimed to verify the usefulness of our proposed nasal symptom questionnaire (NSQ) scoring system and to determine predictors linked to the improvement in nasal symptoms in chronic rhinosinusitis (CRS) patients undergoing endoscopic sinus surgery (ESS). PATIENTS AND METHODS: Ninety-one CRS patients undergoing ESS and 144 volunteers with results of NSQ available were enrolled. The NSQ consists of 10 items. Receiver-operating-characteristic (ROC) curve, area under the ROC curve (AUC), internal consistency, and test-retest reproducibility of the NSQ were analyzed...
October 11, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30304730/extension-of-the-clinical-significance-of-the-cog
#2
Kaishi Wang, Yi Jiang, Zhifei Zhang, Yongtian Lu, Yusu Ni
OBJECTIVE: To study the clinical anatomy of the epitympanum, the attic, and its medial wall, to try to discover a new clinical operation-related anatomical landmark, and to investigate the adjacent anatomical relationship with this landmark. MATERIALS AND METHODS: Eight donor temporal bone specimens were dissected endoscopically. For 29 healthy persons (17 males and 12 females), CT images of the temporal bone (57 ears) were taken, 3-dimensional (3-D) reconstruction and multidimensional plane reconstruction were performed, and identification and assessment of 3-D spatial relationships between any 2 of these complex structures were done...
October 10, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30278463/anaesthesia-and-perioperative-care-for-transoral-robotic-surgery
#3
J Jeyarajah, I Ahmad, Eva Jacovou
Minimally invasive surgical techniques have gained increasing interest in recent years for their conferred recovery and postoperative advantages. Robot-assisted surgery requires special consideration for anaesthetic and perioperative management. The introduction of robot- assisted intra-oral surgery has important implications on anaesthesia provision, airway management and patient safety. Due to its relatively novel use we explore these considerations alongside our own experience in this field.
October 2, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30253396/preoperative-serum-thyroglobulin-level-as-a-useful-predictive-marker-to-differentiate-thyroid-cancer
#4
Ayhan Kars, Bülent Aktan, Korhan Kilic, M Sedat Sakat, M Sıtkı Gözeler, Özgür Yörük, Vahit Mutlu, Sinan Yılmaz
INTRODUCTION: Thyroid cancer is the most common endocrine system cancer. Although fine-needle aspiration biopsy is the most commonly used method for diagnosis, it is not always sufficient. The aim of this study was to investigate the influence of preoperative serum thyroglobulin (Tg) concentration on differentiated thyroid cancer risk. MATERIAL AND METHODS: A total of 133 patients who underwent total thyroidectomy due to various indications at the Ear-Nose-Throat Department, Ataturk University Medical School, between April 2015 and December 2015, were included in this prospective study...
September 25, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30212832/the-telomerase-and-alternative-lengthening-of-telomeres-mechanisms-regulate-laryngeal-cancer-cell-apoptosis-via-the-pi3k-akt-pathway
#5
Fei Wang, Jian-Fei Sheng, Lei Cai, Yong Xu, Hua Liao, Ze-Zhang Tao
PURPOSE: To investigate the possible telomerase and alternative lengthening of telomeres (ALT) mechanisms influencing the apoptosis of laryngeal squamous cells. MATERIALS AND METHODS: The effects of the telomerase mechanism were observed by knockdown of human telomerase reverse transcriptase (hTERT). The ALT mechanism was induced by silencing related genes including TRF2, RAD51, and NBS1. Effects of telomerase and ALT mechanisms on tumor development were confirmed by xenograft tumors model...
September 13, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30205367/conservative-treatment-versus-surgery-for-laryngeal-contact-granuloma-a-prospective-study
#6
Min Chen, Jian Chen, Yue Yang, Chang-Jiang Li, Hai-Tao Wu, Lei Chen
AIMS: To confirm the efficacy of conservative treatment for laryngeal contact granuloma and identify factors influencing treatment outcome. METHODS: In this prospective study, patients with laryngeal contact granuloma were divided into a group receiving conservative treatment and a group undergoing surgery. Efficacy was assessed by analyzing the complete response after a 48-week follow-up. The association of treatment outcome with clinical factors was then evaluated...
September 11, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30130763/long-term-outcomes-after-performing-tympanoplasty-without-mastoidectomy-for-active-and-inactive-noncholesteatomatous-chronic-otitis-media
#7
Jie Huang, Zeqing Li, Kunmin Wu, Wuqing Wang
OBJECTIVE: This study aimed to assess long-term outcomes after performing tympanoplasty without mastoidectomy (TWOM) for active and inactive noncholesteatomatous chronic otitis media (COM) and to estimate the optimal time for surgery. METHODS: The patients were placed into an active ear group (group A) and an inactive ear group (group B). All patients were followed up for 5 years after TWOM. RESULTS: Ninety-two cases among 113 achieved dry ears in half a month to 1 month...
August 21, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30121670/comparable-electrode-impedance-and-speech-perception-at-12-months-after-cochlear-implantation-using-round-window-versus-cochleostomy-an-analysis-of-40-patients
#8
Xiaoting Cheng, Bing Wang, Yangwenyi Liu, Yasheng Yuan, Yilai Shu, Bing Chen
OBJECTIVE: The objective of this study was to examine whether cochlear implantation using the round window (RW) route versus cochleostomy achieves comparable electrode impedance and hearing results. METHODS: This retrospective analysis included 40 patients receiving a cochlear implant (REZ-1): 20 using the RW approach and the remaining 20 using cochleostomy. Electrode impedance and tone, vowel, consonant, disyllable and sentence perception were measured during and after the implantation...
August 17, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30121650/morphological-evaluation-of-thyroid-cartilage-invasion-in-early-glottic-tumors-involving-the-anterior-commissure
#9
Henrique Wendling Sava, Rogério Aparecido Dedivitis, Gustavo Rosa Gameiro, Elio Gilberto Pfuetzenreiter, Ricardo Camillo de Almeida, Leandro Luongo Matos, Claudio Roberto Cernea
INTRODUCTION: The anterior commissure is an area of glottic cancer infiltration, even in early stages. OBJECTIVE: To evaluate the invasion by tumors into the anterior commissure cartilage in surgical specimens of frontolateral laryngectomy. METHODS: Forty-eight patients who had undergone frontolateral laryngectomy for T1b/T2 squamous cell carcinoma were included. Epidemiological and clinical aspects as well as morphological histopathological analysis were evaluated...
August 17, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30110688/the-positive-effect-of-sialendoscopy-with-irrigation-lavage-for-sialadenitis-without-sialolithiasis-or-stenosis
#10
David Schwarz, Konrad Johannes Stuermer, Jan Christoffer Luers
AIMS: The aim of the study was to evaluate different irrigation solutions during sialendoscopy to reduce complaints caused by sialodochitis. METHODS: The investigators designed and implemented a retrospective study composed of 94 patients with sialodochitis but no sialolithiasis or relevant stenosis of the salivary duct system. Three different irrigations (normal saline, cortisone single-shot, and cortisone) were used. After the sialendoscopy, the patients were asked about the current status of the affected salivary gland, and the quantity and quality of the gland swelling/inflammation over a follow-up period of 11...
August 15, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30092593/correlation-between-serum-squamous-cell-carcinoma-antigen-level-and-tumor-volume-in-head-and-neck-cancer
#11
Kitti Jantharapattana, Teerapol Kotamnivates, Siriporn Hirunpat, Roongrueng Jarumanokul
PURPOSE OF STUDY: An association of squamous cell carcinoma antigen (SCC-Ag) level with cancer prognosis has been reported in many studies. Our investigators conducted the first study determining a correlation between the SCC-Ag level and the tumor volume in head and neck cancer. PROCEDURES: The SCC-Ag level of patients were measured from the serum, whilst the tumor volume was calculated by the ellipsoid formula and verified by logistic software on radiology. The correlation between SCC-Ag level and tumor volume was analyzed...
August 9, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30092567/eight-items-to-check-on-a-temporal-bone-ct-scan
#12
Jose Fernando Polanski, Lucas Resende Lucinda, Thomas Linder
Imaging data provided by computed tomography scans of the temporal bone are fundamental for both the diagnosis and treatment of diseases affecting this complex structure. Despite its importance, the expertise required to analyze this exam is seldom properly acquired as it is time-consuming and often neglected among young doctors and even otolaryngologists. Physicians may not even have a look at the scans but rely only on radiology reports. Radiologists, on the other hand, may not describe the individual scans the same way as clinicians...
August 9, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30016769/transoral-robotic-surgery-for-oropharyngeal-cancer
#13
Vinidh Paleri, Hannah Fox, Stuart Winter
Transoral robotic surgery has shown significant promise in the management of oropharyngeal cancer since its description in 2007. The oncological efficacy of this procedure has been proven in several single-centre studies, multicentre collaborative publications and systematic reviews. The rapid take-up of transoral robotic surgery shows greater acceptance by professionals and is associated with a relatively short learning curve. This overview discusses the rationale and principles underlying the use of transoral robotic surgery in primary and recurrent oropharyngeal cancer and the emerging role for this technique in diagnosing the unknown primary site, and summarizes ongoing research in this field...
July 17, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29936512/transoral-robotic-surgery-for-obstructive-sleep-apnoea-hypopnoea-syndrome
#14
Tom Vauterin, George Garas, Asit Arora
Obstructive sleep apnoea-hypopnoea (OSAH) syndrome constitutes a major health care problem. Surgical modalities for the treatment of OSAH are regaining momentum in view of the increasing prevalence of OSAH and the low compliance rates associated with continuous positive airway pressure. There are several investigations to complement clinical examination in accurately determining the level of airway collapse to ensure correct patient selection and a targeted surgical approach. The most commonly employed include drug-induced sleep endoscopy and imaging with the tongue base and epiglottis often revealed as the major sites of airway narrowing during sleep...
June 22, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29936505/transoral-robotic-surgery-image-guidance-and-augmented-reality
#15
Philip Pratt, Asit Arora
Transoral robotic surgery (TORS) is being used increasingly as an alternative to conventional open procedures, as its minimally invasive approach results in significant benefits for the patient. This includes faster recovery times and better functional outcomes, less postoperative pain and morbidity associated with open access, shorter operative times, and a reduction in the risk of infection. However, the confined working spaces and sensory deficit, due to a lack of haptic sensation, and proximity to critical vasculature and other vitally important anatomical structures bestow significant challenges on the surgeon...
June 22, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29925061/robotic-head-and-neck-surgery-history-technical-evolution-and-the-future
#16
George Garas, Asit Arora
The first application of robotic technology in surgery was described in 1985 when a robot was used to define the trajectory for a stereotactic brain biopsy. Following its successful application in a variety of surgical operations, the da Vinci® robot, the most widely used surgical robot at present, made its clinical debut in otorhinolaryngology and head and neck surgery in 2005 when the first transoral robotic surgery (TORS) resections of base of tongue neoplasms were reported. Subsequently, the indications for TORS rapidly expanded, and they now include tumours of the oropharynx, hypopharynx, parapharyngeal space, and supraglottic larynx, as well as obstructive sleep apnoea (OSA)...
June 20, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29788019/robotic-thyroid-surgery-current-perspectives-and-future-considerations
#17
Patrick Aidan, Asit Arora, Balazs Lorincz, Neil Tolley, George Garas
Robotic transaxillary thyroidectomy, pioneered in South Korea, is firmly established throughout the Far East but remains controversial in Western practice. This relates to important population differences (anthropometry and culture) compounded by the smaller mean size of thyroid nodules operated on in South Korea due to a national thyroid cancer screening programme. There is now level 2 evidence (including from Western World centres) to support the safety, feasibility, and equivalence of the robotic approach to its open counterpart in terms of recurrent laryngeal nerve injury, hypoparathyroidism, haemorrhage, and oncological outcomes for differentiated thyroid cancer...
May 22, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29788003/robotic-parathyroid-surgery-current-perspectives-and-future-considerations
#18
Asit Arora, George Garas, Neil Tolley
Robotic parathyroidectomy represents a novel surgical approach in the treatment of primary hyperparathyroidism when the parathyroid adenoma has been pre-operatively localised. It represents the "fourth generation" in the evolution of parathyroid surgery following a process of surgical evolution from cervicotomy and 4-gland exploration to a variety of minimally invasive, open and endoscopic, targeted approaches. The existing evidence (levels 2-3) supports it as a feasible and safe technique with equivalent results to targeted open parathyroidectomy for primary hyperparathyroidism in carefully selected patients...
May 22, 2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/30041251/congenital-cholesteatoma-the-silent-pathology
#19
Badr Eldin Mostafa, Lobna El Fiky
BACKGROUND: Congenital cholesteatomas (CC) arise from epithelial remnants around the petrous bone. They enlarge gradually causing progressive destruction and functional damage to the ear and surrounding structures. Because of their insidious course, most patients are misdiagnosed and present late with complications. METHODS: This is a retrospective study of 41 cases diagnosed as CC and followed up for 2 years. All patients underwent full audiological evaluation and a radiological study (CT, MRI)...
2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
https://www.readbyqxmd.com/read/29996129/mandibular-myalgia-and-miniscule-meckel-s-caves
#20
Srihari Sundararajan, Laurie A Loevner, Suyash Mohan
Trigeminal neuropathy manifests as episodic sharp, shooting pain in the maxillofacial region. Contributory etiologies are myriad, ranging from central pathology affecting its origin in the brainstem to peripheral processes affecting their distal-most insertion sites. We present a case of bilateral hypoplastic Meckel's caves in an adult patient leading to the clinical symptomology of trigeminal neuralgia. To the best of our knowledge, this is the only report of its kind highlighting this anatomic variant.
2018: ORL; Journal for Oto-rhino-laryngology and its related Specialties
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