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Environmental Health Perspectives

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https://www.readbyqxmd.com/read/29351546/accessing-an-expanded-exposure-science-module-at-the-comparative-toxicogenomics-database
#1
Cynthia J Grondin, Allan Peter Davis, Thomas C Wiegers, Jolene A Wiegers, Carolyn J Mattingly
The Comparative Toxicogenomics Database (CTD; http://ctdbase.org) is a free resource that provides manually curated information on chemical, gene, phenotype, and disease relationships to advance understanding of the effect of environmental exposures on human health. Four core content areas are independently curated: chemical-gene interactions, chemical-disease and gene-disease associations, chemical-phenotype interactions, and environmental exposure data (e.g., effects of chemical stressors on humans). Since releasing exposure data in 2015, we have vastly increased our coverage of chemicals and disease/phenotype outcomes; greatly expanded access to exposure content; added search capability by stressors, cohorts, population demographics, and measured outcomes; and created user-specified displays of content...
January 18, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29351544/long-term-exposure-to-fine-particulate-matter-blood-pressure-and-incident-hypertension-in-taiwanese-adults
#2
Zilong Zhang, Cui Guo, Alexis K H Lau, Ta-Chien Chan, Yuan Chieh Chuang, Changqing Lin, Wun Kai Jiang, Eng-Kiong Yeoh, Tony Tam, Kam S Woo, Bryan P Yan, Ly-Yun Chang, Martin C S Wong, Xiang Qian Lao
BACKGROUND: Long-term exposure to particulate matter (PM) air pollution may increase blood pressure and the risk of hypertension. However, epidemiological evidence is scarce and inconsistent. OBJECTIVES: We investigated the associations between long-term exposure to PM with an aerodynamic diameter <2.5μm (PM2.5), blood pressure, and incident hypertension in a large Taiwanese cohort. METHODS: We studied 361,560 adults ≥18y old from a large cohort who participated in a standard medical examination program during 2001 to 2014...
January 18, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29351545/love-song-blues-dehp-alters-courtship-vocalizations-in-mice
#3
Nate Seltenrich
No abstract text is available yet for this article.
January 17, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29342453/fine-particulate-air-pollution-and-the-expression-of-micrornas-and-circulating-cytokines-relevant-to-inflammation-coagulation-and-vasoconstriction
#4
Renjie Chen, Huichu Li, Jing Cai, Cuicui Wang, Zhijing Lin, Cong Liu, Yue Niu, Zhuohui Zhao, Weihua Li, Haidong Kan
BACKGROUND: MicroRNAs (miRNAs) are a key factor in epigenetic regulation of gene expression, but miRNA responses to fine particulate matter (PM2.5) air pollution and their potential contribution to cardiovascular effects of PM2.5 are unknown. OBJECTIVE: We explored the potential influence of PM2.5 on the expression of selected cytokines relevant to systemic inflammation, coagulation, and vasoconstriction, and on miRNAs that may regulate their expression. METHODS: We designed a double-blind, randomized crossover study in which true and sham air purifiers were used to expose 55 healthy young adult students in Shanghai, China, to reduced or ambient levels of indoor PM2...
January 17, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29342451/decadal-changes-in-the-edible-supply-of-seafood-and-methylmercury-exposure-in-the-united-states
#5
Elsie M Sunderland, Miling Li, Kurt Bullard
BACKGROUND: Methylmercury (MeHg) exposure is associated with adverse effects on neurodevelopment and cardiovascular health. Previous work indicates most MeHg is from marine fish sold in the commercial market, but does not fully resolve supply regions globally. This information is critical for linking changes in environmental MeHg levels to human exposure in the U.S. population. OBJECTIVES: We used available data to estimate the geographic origins of seafood consumed in the United States (major ocean basins, coastal fisheries, aquaculture, freshwater) and how shifts in edible supply affected MeHg exposures between 2000-2002 and 2010-2012...
January 16, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29342452/estimated-effect-of-temperature-on-years-of-life-lost-a-retrospective-time-series-study-of-low-middle-and-high-income-regions
#6
Maquins Odhiambo Sewe, Aditi Bunker, Vijendra Ingole, Thaddaeus Egondi, Daniel Oudin Åström, David M Hondula, Joacim Rocklöv, Barbara Schumann
BACKGROUND: Numerous studies have reported a strong association between temperature and mortality. Additional insights can be gained from investigating the effects of temperature on years of life lost (YLL), considering the life expectancy at the time of death. OBJECTIVES: The goal of this work was to assess the association between temperature and YLL at seven low-, middle-, and high-income sites. METHODS: We obtained meteorological and population data for at least nine years from four Health and Demographic Surveillance Sites in Kenya (western Kenya, Nairobi), Burkina Faso (Nouna), and India (Vadu), as well as data from cities in the United States (Philadelphia, Phoenix) and Sweden (Stockholm)...
January 12, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29329102/arsenic-exposure-from-drinking-water-and-urinary-metabolomics-associations-and-long-term-reproducibility-in-bangladesh-adults
#7
Fen Wu, Liang Chi, Hongyu Ru, Faruque Parvez, Vesna Slavkovich, Mahbub Eunus, Alauddin Ahmed, Tariqul Islam, Muhammad Rakibuz-Zaman, Rabiul Hasan, Golam Sarwar, Joseph H Graziano, Habibul Ahsan, Kun Lu, Yu Chen
BACKGROUND: Chronic exposure to inorganic arsenic from drinking water has been associated with a host of cancer and noncancer diseases. The application of metabolomics in epidemiologic studies may allow researchers to identify biomarkers associated with arsenic exposure and its health effects. OBJECTIVE: Our goal was to evaluate the long-term reproducibility of urinary metabolites and associations between reproducible metabolites and arsenic exposure. METHODS: We studied samples and data from 112 nonsmoking participants (58 men and 54 women) who were free of any major chronic diseases and who were enrolled in the Health Effects of Arsenic Longitudinal Study (HEALS), a large prospective cohort study in Bangladesh...
January 12, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29329101/spatial-variation-of-endotoxin-concentrations-measured-in-ambient-pm10-in-a-livestock-dense-area-implementation-of-a-land-use-regression-approach
#8
Myrna M T de Rooij, Dick J J Heederik, Erik J H M van Nunen, Isabella J van Schothorst, Catharina B M Maassen, Gerard Hoek, Inge M Wouters
BACKGROUND: Results from studies on residential health effects of livestock farming are inconsistent, potentially due to simple exposure proxies used (e.g., livestock density). Accuracy of these proxies compared with measured exposure concentrations is unknown. OBJECTIVES: We aimed to assess spatial variation of endotoxin in PM10 (particulate matter ≤10μm) at residential level in a livestock-dense area, compare simple livestock exposure proxies to measured endotoxin concentrations, and evaluate whether land-use regression (LUR) can be used to explain spatial variation of endotoxin...
January 11, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29329100/a-web-based-system-for-bayesian-benchmark-dose-estimation
#9
Kan Shao, Andrew J Shapiro
BACKGROUND: Benchmark dose (BMD) modeling is an important step in human health risk assessment and is used as the default approach to identify the point of departure for risk assessment. A probabilistic framework for dose-response assessment has been proposed and advocated by various institutions and organizations; therefore, a reliable tool is needed to provide distributional estimates for BMD and other important quantities in dose-response assessment. OBJECTIVES: We developed an online system for Bayesian BMD (BBMD) estimation and compared results from this software with U...
January 11, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29326091/erratum-regulation-of-chromatin-assembly-and-cell-transformation-by-formaldehyde-exposure-in-human-cells
#10
Danqi Chen, Lei Fang, Shenglin Mei, Hongjie Li, Xia Xu, Thomas L Des Marais, Kun Lu, X Shirley Liu, Chunyuan Jin
[This corrects the article DOI: 10.1289/EHP1275.].
January 3, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29298162/prenatal-maternal-serum-concentrations-of-per-and-polyfluoroalkyl-substances-in-association-with-autism-spectrum-disorder-and-intellectual-disability
#11
Kristen Lyall, Vincent M Yau, Robin Hansen, Martin Kharrazi, Cathleen K Yoshida, Antonia M Calafat, Gayle Windham, Lisa A Croen
BACKGROUND: Emerging work has examined neurodevelopmental outcomes following prenatal exposure to per- and polyfluoroalkyl substances (PFAS), but few studies have assessed associations with autism spectrum disorder (ASD). OBJECTIVES: Our objective was to estimate associations of maternal prenatal PFAS concentrations with ASD and intellectual disability (ID) in children. METHODS: Participants were from a population-based nested case-control study of children born from 2000 to 2003 in southern California, including children diagnosed with ASD (n=553), ID without autism (n=189), and general population (GP) controls (n=433)...
January 2, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29269335/uterine-artery-flow-and-offspring-growth-in-long-evans-rats-following-maternal-exposure-to-ozone-during-implantation
#12
Colette N Miller, Janice A Dye, Allen D Ledbetter, Mette C Schladweiler, Judy H Richards, Samantha J Snow, Charles E Wood, Andres R Henriquez, Leslie C Thompson, Aimen K Farraj, Mehdi S Hazari, Urmila P Kodavanti
BACKGROUND: Epidemiological studies suggest that increased ozone exposure during gestation may compromise fetal growth. In particular, the implantation stage of pregnancy is considered a key window of susceptibility for this outcome. OBJECTIVES: The main goals of this study were to investigate the effects of short-term ozone inhalation during implantation on fetal growth outcomes and to explore the potential for alterations in uterine arterial flow as a contributing mechanism...
December 21, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29262383/erratum-sanitary-sewer-overflows-and-emergency-room-visits-for-gastrointestinal-illness-analysis-of-massachusetts-data-2006-2007
#13
Jyotsna S Jagai, Stephanie DeFlorio-Barker, Cynthia J Lin, Elizabeth D Hilborn, Timothy J Wade
[This corrects the article DOI: 10.1289/EHP2048.].
December 19, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29233797/manure-irrigation-environmental-benefits-potential-human-health-risks
#14
Nate Seltenrich
No abstract text is available yet for this article.
December 12, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29233796/tracking-trachoma-how-the-gambia-is-eliminating-an-ancient-disease
#15
Jori Lewis
No abstract text is available yet for this article.
December 11, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29233795/using-microsimulation-to-estimate-the-future-health-and-economic-costs-of-salmonellosis-under-climate-change-in-central-queensland-australia
#16
Dimity Maree Stephen, Adrian Gerard Barnett
BACKGROUND: The incidence of salmonellosis, a costly foodborne disease, is rising in Australia. Salmonellosis increases during high temperatures and rainfall, and future incidence is likely to rise under climate change. Allocating funding to preventative strategies would be best informed by accurate estimates of salmonellosis costs under climate change and by knowing which population subgroups will be most affected. OBJECTIVE: We used microsimulation models to estimate the health and economic costs of salmonellosis in Central Queensland under climate change between 2016 and 2036 to inform preventative strategies...
December 11, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29225196/in-the-neighborhood-of-18-million-estimating-how-many-people-live-near-oil-and-gas-wells
#17
Lindsey Konkel
No abstract text is available yet for this article.
December 7, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29215333/erratum-new-blood-the-promise-of-environmental-health-citizen-science-projects
#18
Nancy Averett
[This corrects the article DOI: 10.1289/EHP2484.].
December 6, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29212063/erratum-associations-between-ambient-fine-particulate-oxidative-potential-and-cardiorespiratory-emergency-department-visits
#19
Joseph Y Abrams, Rodney J Weber, Mitchel Klein, Stefanie E Sarnat, Howard H Chang, Matthew J Strickland, Vishal Verma, Ting Fang, Josephine T Bates, James A Mulholland, Armistead G Russell, Paige E Tolbert
[This corrects the article DOI: 10.1289/EHP1545.].
December 5, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29212062/mix-masters-using-a-new-tool-to-identify-commonly-occurring-chemical-mixtures
#20
Carrie Arnold
No abstract text is available yet for this article.
December 5, 2017: Environmental Health Perspectives
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