Tianwei Meng, Zhiping Liu, Jiawen Liu, Xiaobing Zhang, Chengjia Li, Jiarui Li, Boyu Wang, Yinxiong He, Zengguang Fan, Shilong Xin, Jia Chen, Rui Qie
BACKGROUND: Previous observational studies have suggested associations between Coronary Heart Disease (CHD) and Mental Health Disorders (MHD). However, the causal nature of these relationships has remained elusive. OBJECTIVE: The purpose of this study is to elucidate the causal relationships between eight distinct types of CHD and six types of MHD using Mendelian randomization (MR) analysis. METHODS: The MR analysis employed a suite of methods including inverse variance-weighted (IVW), MR-Egger, weighted mode, weighted median, and simple mode techniques...
April 8, 2024: Heart & Lung: the Journal of Critical Care