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Scandinavian Journal of Rheumatology

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https://www.readbyqxmd.com/read/29775118/blood-flow-restricted-resistance-training-in-patients-with-sporadic-inclusion-body-myositis-a-randomized-controlled-trial
#1
A N Jørgensen, P Aagaard, U Frandsen, E Boyle, L P Diederichsen
OBJECTIVES: To investigate the effect of 12 weeks of low-load blood-flow restricted resistance (BFR) training on self-reported and objective physical function, and maximal muscle strength in patients with sporadic inclusion body myositis (sIBM). METHOD: Twenty-two patients with sIBM were randomized into a training group (BFR group) or a non-exercising control group, according to CONsolidated Standards Of Reporting Trials (CONSORT) guidelines. The BFR group performed 12 weeks of BFR training twice per week...
May 18, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29774784/moderate-alcohol-consumption-is-associated-with-increased-radiological-progression-in-women-but-not-in-men-with-early-rheumatoid-arthritis-results-from-the-espoir-cohort-%C3%A3-tude-et-suivi-des-polyarthrites-indiff%C3%A3-renci%C3%A3-es-r%C3%A3-centes
#2
F Sageloli, J L Quesada, B Fautrel, C Salliot, P Gaudin, A Baillet
OBJECTIVE: We conducted this study to determine whether alcohol consumption influences radiological progression in early rheumatoid arthritis (RA). METHOD: Patients fulfilling the European League Against Rheumatism/American College of Rheumatology 2010 criteria in the early arthritis cohort ESPOIR (Étude et Suivi des Polyarthrites Indifférenciées Récentes) were included in this study. Alcohol consumption was collected at baseline and at each visit. We classified alcohol consumption into three groups: abstinent (0 g/day), moderate (≤ 20 g/day for women, ≤ 30 g/day for men), and abuse (> 20 g/day for women, > 30 g/day for men)...
May 18, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29741136/mortality-and-its-predictors-in-patients-with-rheumatoid-arthritis-a-danish-population-based-inception-cohort-study
#3
J K Pedersen, R Holst, J Primdahl, A J Svendsen, K Hørslev-Petersen
OBJECTIVES: To investigate mortality and its predictors in a retrospectively defined population-based rheumatoid arthritis (RA) inception cohort Method: We included patients ascertained with incident RA from a region in the southern part of Denmark from 1995 to 2002. All patients fulfilled the 1987 American College of Rheumatology criteria for RA. The patients were followed from RA classification until death, emigration, or end of follow-up on 31 December 2013. We used personal record linkage with national public registers to obtain information on education, employment, cohabitation, comorbidity, and vital status...
May 9, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29741129/decreased-antibodies-against-rubella-in-previously-vaccinated-treatment-na%C3%A3-ve-childhood-systemic-lupus-erythematous-patients-a-prospective-case-control-study
#4
D N Maritsi, S Coffin, M Onoufriou, N Spyridis, M N Tsolia
No abstract text is available yet for this article.
May 9, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29741122/long-term-risk-and-outcome-of-infection-related-hospitalization-in-granulomatosis-with-polyangiitis-a-nationwide-population-based-cohort-study
#5
M Faurschou, N Obel, B Baslund
OBJECTIVE: To assess the long-term risk and outcome of infection-related hospitalization (IH) among patients with granulomatosis with polyangiitis (GPA). METHOD: We used administrative databases to establish a GPA cohort (n = 398), construct a comparison cohort of population controls (n = 3980), and collect clinical data. Cox regression analyses were used to determine hazard ratios (HRs) as a measure of relative risk. Follow-up began at date of GPA diagnosis and continued for up to 10 years...
May 9, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29701536/concentrations-of-infliximab-and-anti-drug-antibodies-in-relation-to-clinical-response-in-patients-with-rheumatoid-arthritis
#6
F Siljehult, L Ärlestig, C Eriksson, S Rantapää-Dahlqvist
OBJECTIVE: The efficacy of anti-tumour necrosis factor-α (anti-TNF-α) treatment with infliximab (IFX) may be reduced by the development of anti-drug antibodies (ADAs). This study evaluated drug concentration and the presence of ADAs, relative to response, in rheumatoid arthritis (RA) patients treated with IFX. METHOD: Ninety-four RA patients were consecutively included and assessed for disease activity at baseline, and after 14, and 30 or 52 weeks. Serum IFX concentration and ADAs were analysed using in-house enzyme-linked immunosorbent assays...
April 27, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29683356/is-current-smoking-status-and-its-relationship-to-anti-cyclic-citrullinated-peptide-antibodies-a-predictor-of-worse-response-to-biological-therapies-in-rheumatoid-arthritis-patients
#7
V Torrente-Segarra, S A Bergstra, K Salomon-Escoto, Jap Da Silva, D J Veale, S Al-Emadi, Twj Huizinga
OBJECTIVE: To assess the association between smoking, anti-cyclic citrullinated peptide (anti-CCP) antibody status, and clinical efficacy of biological therapies in rheumatoid arthritis (RA) patients. METHOD: This retrospective clinical practice setting study included 1349 RA patients from the METEOR database (aged >18 years). We collected data on sociodemographics, smoking status (smoker, <10, 10-19, and >20 cigarettes/day; ex-smoker; non-smoker), baseline disease activity parameters and anti-CCP, previous disease-modifying anti-rheumatic drugs (DMARDs), biological therapy, combined therapy (steroids and DMARDs), and follow-up disease activity...
April 23, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29631467/papulonodules-malar-rash-and-arthritis-in-a-male
#8
L-Q Zhang, C Tan
No abstract text is available yet for this article.
April 10, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29631459/anti-interleukin-6-receptor-antibody-prevents-loss-of-bone-structure-and-bone-strength-in-collagen-induced-arthritis-mice
#9
H Yoshida, M Suzuki, K Tanaka, S Takeda, K Yogo, Y Matsumoto
OBJECTIVE: Rheumatoid arthritis (RA) is a disease that typically induces secondary osteoporosis, which increases the risk of bone fractures. Anti-interleukin-6 (IL-6) receptor antibody is used to treat RA; however, its effect on bone strength is not clear. Therefore, we investigated the influence of MR16-1, an anti-mouse IL-6 receptor antibody, on bone structure and femoral strength in a collagen-induced arthritis (CIA) mouse model. METHOD: DBA/1J mice were immunized by intradermal injection of bovine type II collagen...
April 10, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29611446/costs-and-disease-activity-in-early-rheumatoid-arthritis-in-1996-2000-and-2006-2011-improved-outcome-and-shift-in-distribution-of-costs-a-two-year-follow-up
#10
M Husberg, L Bernfort, E Hallert
OBJECTIVE: To evaluate changes in healthcare utilization, costs, and disease activity from 1996 to 2011 for patients with early rheumatoid arthritis (RA). METHOD: Two cohorts of patients with early RA, included in 1996-1998 (T1) and 2006-2009 (T2), were followed regularly. Healthcare utilization, costs, and disease activity were compared between cohorts during 2 years after diagnosis. RESULTS: Disease activity was significantly improved in T2 vs T1...
April 3, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29542372/interleukin-6-and-iga-rheumatoid-factor-are-crucial-for-baseline-erosiveness-and-anti-citrullinated-peptide-antibodies-for-radiographic-progression-in-early-rheumatoid-arthritis-treated-according-to-a-treat-to-target-strategy
#11
A L Fedele, L Petricca, B Tolusso, S Alivernini, S Canestri, C Di Mario, S L Bosello, G Ferraccioli, E Gremese
OBJECTIVES: To define baseline clinical and immunological characteristics [anti-citrullinated peptide antibodies (ACPAs), immunoglobulin M (IgM)- and IgA-rheumatoid factor (RF), and interleukin-6 (IL-6) levels] involved in determining baseline erosiveness, outcome, and radiographic progression among seropositive and seronegative early rheumatoid arthritis (ERA) patients. METHOD: The 408 ERA patients enrolled in the study were monitored every 3 months according to the treat-to-target strategy...
March 15, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29532736/minocycline-associated-polyarteritis-nodosa-and-self-limiting-hepatitis-a-reminder-of-a-potentially-re-emerging-culprit-in-drug-induced-autoimmune-syndromes
#12
Mjs Parker, N W McGill
No abstract text is available yet for this article.
March 13, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29528272/angiogenic-and-inflammatory-biomarkers-for-screening-and-follow-up-in-patients-with-pulmonary-arterial-hypertension
#13
D Kylhammar, R Hesselstrand, S Nielsen, C Scheele, G Rådegran
OBJECTIVE: To identify circulating angiogenic and inflammatory biomarkers with potential in screening for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc), and in early diagnosis and determination of treatment response in PAH. METHOD: Plasma samples were taken at the time of PAH diagnosis and at treatment follow-up after a median (interquartile range) of 4 months (3-9.8 months) in idiopathic (n = 9) and SSc-associated PAH (n = 11). In patients with SSc-associated PAH, plasma samples had also been gathered a median of 2 years (0...
March 12, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29495920/multifocal-vertebral-sclerosing-bone-changes-and-soft-tissue-masses-caused-by-hodgkin-s-lymphoma-in-a-patient-with-systemic-lupus-erythematosus-a-case-report
#14
S Krabbe, J Helweg-Larsen, A Loft, S Jacobsen
No abstract text is available yet for this article.
March 2, 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/29376470/a-case-of-refractory-acute-sarcoid-myopathy-successfully-treated-with-intravenous-immunoglobulin
#15
M Kono, M Kono, S Jodo
No abstract text is available yet for this article.
March 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28927315/systematic-review-and-meta-analysis-of-the-epidemiology-of-polyautoimmunity-in-sj%C3%A3-gren-s-syndrome-secondary-sj%C3%A3-gren-s-syndrome-focusing-on-autoimmune-rheumatic-diseases
#16
REVIEW
H Alani, J R Henty, N L Thompson, E Jury, C Ciurtin
OBJECTIVE: The epidemiology of polyautoimmunity in Sjögren's syndrome (secondary Sjögren's syndrome - sSS) is not well defined and has not been investigated before using a systematic approach. We conducted a systematic review of the epidemiology of sSS associated with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), scleroderma, and myositis, assessing the prevalence rates (PRs) and clinical and serological features of sSS. METHOD: A systematic literature search of PubMed and Embase databases (updated to March 2016) was performed to identify all published data on PR, demographic profile, clinical manifestations, laboratory features, and causes of death associated with sSS...
March 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28891743/high-intensity-cardiorespiratory-and-strength-exercises-reduced-emotional-distress-and-fatigue-in-patients-with-axial-spondyloarthritis-a-randomized-controlled-pilot-study
#17
RANDOMIZED CONTROLLED TRIAL
S H Sveaas, I J Berg, C Fongen, S A Provan, H Dagfinrud
OBJECTIVE: To investigate the effect of high-intensity exercise on emotional distress, fatigue, and ability to do a full day's activities in patients with axial spondyloarthritis (axSpA). METHOD: A total of 28 physically inactive axSpA patients were randomized to either an exercise group (EG), which performed 12 weeks of cardiorespiratory and strength exercises, or a control group (CG), which received treatment as usual. The outcomes reported in this paper are secondary outcomes in the trial and included emotional distress (General Health Questionnaire-12, 0-36, 36 = worst), fatigue [numeric rating scale (NRS), 0-10, 10 = worst], and ability to do a full day's activities (NRS, 0-10, 10 = worst)...
March 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28862513/relationship-between-glucocorticoid-dose-and-adverse-events-in-systemic-lupus-erythematosus-data-from-a-randomized-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
S Emamikia, C Gentline, K Chatzidionysiou, L Arnaud, R van Vollenhoven
OBJECTIVE: The aim was to obtain a better understanding of the relationship between exposure to glucocorticoids (GCs) and adverse events (AEs) reported in a randomized controlled trial (RCT) in systemic lupus erythematosus (SLE) patients. METHOD: We used data from the BLISS-76 trial on belimumab. The data were accessed through an agreement under the SHARE mechanism. AEs were grouped according to medical relevance, i.e. based on similarity of symptoms and pathophysiology...
March 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28862099/association-of-killer-cell-immunoglobulin-like-receptor-kir-genes-and-their-hla-ligands-with-susceptibility-to-beh%C3%A3-et-s%C3%A2-disease
#19
H Mohammad-Ebrahim, E Kamali-Sarvestani, M Mahmoudi, M Beigy, J Karami, N Ahmadzadeh, F Shahram
OBJECTIVES: Behçet's disease (BD) is a systemic inflammatory disorder with remissions and exacerbations. It is thought that defects in the natural killer (NK) cell repertoire may be involved in BD through killer cell immunoglobulin-like receptors (KIRs). This study aimed to evaluate KIR and HLA genes, their interactions in BD patients, and their associations with clinical manifestations. METHOD: The presence or absence of KIR and HLA alleles and genotypes was analysed by polymerase chain reaction sequence-specific primer on genomic DNA of 397 BD patients and 300 healthy controls...
March 2018: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28841103/impact-of-patient-reported-flares-on-radiographic-progression-and-functional-impairment-in-patients-with-rheumatoid-arthritis-a-cohort-study-based-on-the-ambra-trial
#20
D Kuettel, J Primdahl, R Christensen, L M Ørnbjerg, K Hørslev-Petersen
OBJECTIVE: To investigate the impact of patient-reported flares on radiographic damage and disability in rheumatoid arthritis (RA). METHOD: Patients with low-active (Disease Activity Score based on 28-joint count with C-reactive protein < 3.2) RA were followed for 2 years. Based on annual questionnaires about incidence of flares, three 'flare phenotypes' were distinguished: no flares (NF), transient flares (TF), and a mixed category reporting persistent joint complaints (PJC) in at least one year...
March 2018: Scandinavian Journal of Rheumatology
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