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Scandinavian Journal of Rheumatology

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https://www.readbyqxmd.com/read/27900875/unprecedented-success-of-rituximab-therapy-for-prednisolone-and-immunosuppressant-resistant-systemic-sclerosis-associated-interstitial-lung-disease
#1
S Ebata, A Yoshizaki, T Fukasawa, K Nakamura, T Yamashita, S Miura, R Saigusa, Y Ichimura, T Takahashi, M Hirabayashi, T Taniguchi, K Akamata, Y Asano, S Sato
No abstract text is available yet for this article.
November 30, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27897449/tacrolimus-in-combination-with-methotrexate-and-corticosteroid-for-the-treatment-of-child-onset-anti-signal-recognition-particle-antibody-positive-necrotizing-myopathy
#2
I Kobayashi, Y Tozawa, M Ueki, S Takezaki, S Watanabe, H Iwafuchi, M Yamada, M Kuwana, T Ariga
No abstract text is available yet for this article.
November 29, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27897446/life-threatening-rituximab-induced-pyoderma-gangrenosum-successfully-treated-with-intravenous-immunoglobulin
#3
J Vikse, A Rygh, K Kaisen, R Omdal
No abstract text is available yet for this article.
November 29, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27885914/chronic-pain-in-older-adults-prevalence-incidence-and-risk-factors
#4
C Larsson, E E Hansson, K Sundquist, U Jakobsson
OBJECTIVES: Chronic pain is common in older adults, yet little is known of its development and the factors that predict its persistence and onset at old age. The aims of this longitudinal cohort study were to examine the prevalence and incidence of chronic pain and to explore possible risk factors for its persistence and onset in a representative sample of older Swedish adults. METHOD: Data were collected through questionnaires and followed up after 12 and 24 months...
November 25, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27775461/effect-of-a-treat-to-target-cyclosporin-on-mri-assessed-synovitis-osteitis-tenosynovitis-bone-erosion-and-joint-space-narrowing-in-early-rheumatoid-arthritis-results-from-a-2-year-randomized-double-blind
#5
S Møller-Bisgaard, B J Ejbjerg, I Eshed, K Hørslev-Petersen, M L Hetland, A G Jurik, H Thomsen, T Torfing, K Stengaard-Pedersen, P Junker, N S Krogh, T Lottenburger, T Ellingsen, L S Andersen, H Skjødt, A J Svendsen, U Tarp, I T Hansen, J Pødenphant, J K Pedersen, H Lindegaard, L G Hanson, A Vestergaard, D Glinatsi, M Østergaard
OBJECTIVES: To investigate whether a treat-to-target strategy based on methotrexate (MTX) and intra-articular (IA) betamethasone suppresses magnetic resonance imaging (MRI)-determined measures of disease activity and reduces joint destruction in early rheumatoid arthritis (eRA) patients, and to investigate whether concomitant cyclosporin A (CyA) provides an additional effect. METHOD: In the 2-year randomized, double-blind, treat-to-target trial CIMESTRA, 160 patients with eRA (< 6 months) were randomized to MTX, intra-articular betamethasone and CyA, or placebo CyA...
October 24, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27775453/the-association-between-insulin-like-growth-factor-1-igf-1-igf-binding-proteins-igfbps-and-the-carboxyterminal-propeptide-of-type-i-procollagen-picp-in-pre-and-postmenopausal-women-with-rheumatoid-arthritis
#6
A Szeremeta, A Jura-Półtorak, K Komosińska-Vassev, A Zoń-Giebel, D Kapołka, K Olczyk
OBJECTIVES: To assess the association between plasma levels of the insulin-like growth factor (IGF) system including IGF-1, IGF-binding proteins (IGFBPs) including IGFBP-1, total (t-)IGFBP-3 and functional (f-)IGFBP-3, and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis (RA). METHOD: Plasma concentrations of IGF-1, IGFBP-1, t-IGFBP-3, f-IGFBP-3, and PICP were measured by immunoassay. RESULTS: No significant difference was observed in plasma IGF-1 levels between pre- and postmenopausal subjects...
October 24, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27766916/a-real-world-risk-analysis-of-biological-treatment-adalimumab-and-etanercept-in-a-country-with-a-high-prevalence-of-tuberculosis-and-chronic-liver-disease-a-nationwide-population-based-study
#7
Y-M Chiu, C-H Tang, S-T Hung, Y-W Yang, C-H Fang, H-Y Lin
OBJECTIVES: Few studies on tumour necrosis factor (TNF) inhibitor-associated tuberculosis (TB) and hepatic events have been performed in regions where these risks are elevated. This study aimed to provide a direct comparison between adalimumab and etanercept in a high-risk population and to address the implications for physicians working with patients in such an environment. METHOD: Data collected from the National Health Insurance Research Database (NHIRD) in Taiwan between 2007 and 2011 were analysed retrospectively for incidences of eight adverse events associated with TNF-α inhibitors...
October 21, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27758124/a-genetic-variant-within-slc30a6-has-a-protective-role-in-the-severity-of-rheumatoid-arthritis
#8
J E Adelino, C Addobbati, A Pontillo, T S Fragoso, Âlbp Duarte, S Crovella, J De Azevedo Silva, P Sandrin-Garcia
No abstract text is available yet for this article.
October 19, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27733091/intra-articular-onabotulinumtoxina-in-osteoarthritis-knee-pain-effect-on-human-mechanistic-pain-biomarkers-and-clinical-pain
#9
L Arendt-Nielsen, G-L Jiang, R DeGryse, C C Turkel
OBJECTIVES: OnabotulinumtoxinA (onabotA) attenuates peripheral nociceptive transduction and consequently neuronal firing. The aim of this mechanistic study was to evaluate the effect of intra-articular (IA) onabotA in patients with painful knee osteoarthritis (OA). METHOD: We conducted a double-blind, randomized, placebo-controlled, 12-week trial using a single ultrasound-guided IA injection of onabotA (200 U). Patients (N = 121) were randomized to receive onabotA (n = 61) or placebo (n = 60)...
October 13, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27733090/monitoring-patients-with-ankylosing-spondylitis-on-anti-tnf-monotherapy-too-much-too-often
#10
W Gunasekera, P Creamer, K Creamer, R Sengupta
No abstract text is available yet for this article.
October 13, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27701937/impact-of-cognitive-impairment-depression-disease-activity-and-disease-damage-on-quality-of-life-in-women-with-systemic-lupus-erythematosus
#11
J Calderón, P Flores, J M Aguirre, G Valdivia, O Padilla, I Barra, L Scoriels, S Herrera, A González, L Massardo
OBJECTIVES: To define the relative role of cognitive impairment, depression, disease activity, and disease damage in the decreased health-related quality of life (HRQoL) frequently observed in systemic lupus erythematosus (SLE) patients. METHOD: We studied 101 Chilean female SLE patients and applied the 12-item Medical Outcomes Study (MOS) Short Form Health Survey version 2 (SF-12v2) to assess HRQoL and the Cambridge Neuropsychological Test Automated Battery (CANTAB) to assess cognitive function...
October 5, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27682742/investigation-of-a-multi-biomarker-disease-activity-score-in-rheumatoid-arthritis-by-comparison-with-magnetic-resonance-imaging-computed-tomography-ultrasonography-and-radiography-parameters-of-inflammation-and-damage
#12
S Krabbe, R Bolce, C H Brahe, U M Døhn, B J Ejbjerg, M L Hetland, E H Sasso, D Chernoff, M S Hansen, L S Knudsen, A Hansen, O R Madsen, M Hasselquist, J Møller, M Østergaard
OBJECTIVES: To investigate the multi-biomarker disease activity (MBDA) score by comparison with imaging findings in an investigator-initiated rheumatoid arthritis (RA) trial (HURRAH trial, NCT00696059). METHOD: Fifty-two patients with established RA initiated adalimumab treatment and had magnetic resonance imaging (MRI), ultrasonography (US), computed tomography (CT), and radiography performed at weeks 0, 26, and 52. Serum samples were analysed using MBDA score assays and associations between clinical measures, MBDA score, and imaging findings were investigated...
September 28, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27682520/x-ray-diffraction-analysis-of-spontaneously-draining-calcinosis-in-scleroderma-patients
#13
V M Hsu, T Emge, N Schlesinger
OBJECTIVES: Calcium hydroxyapatite (HA) is reported to be the major constituent of soft tissue calcinosis in patients with scleroderma (systemic sclerosis, SSc). Mechanical stress and local tissue hypoxia are thought to be important in the pathogenesis of SSc calcinosis. We sought to analyse spontaneously draining material from calcinosis sites in SSc patients using X-ray diffraction (XRD). METHOD: With approval from our local Institutional Review Board (IRB), eligible SSc patients consented to submit their spontaneously draining calcinosis samples for XRD analysis...
September 28, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27636858/anti-m%C3%A3-llerian-hormone-levels-are-not-reduced-in-patients-with-adult-autoinflammatory-diseases-compared-to-healthy-controls
#14
M Henes, K Rall, A Igney-Oertel, F-A Taran, S Brucker, J C Henes
No abstract text is available yet for this article.
September 16, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27635465/prevalence-and-risk-factors-for-left-ventricular-diastolic-dysfunction-in-a-scleroderma-cohort
#15
S Vemulapalli, L Cohen, V Hsu
OBJECTIVES: Left ventricular diastolic dysfunction (LVDD) is more common in systemic sclerosis (SSc) compared to the general population. Focal myocardial ischaemia and fibrosis may be important in its pathogenesis. LVDD is associated with increased mortality and little is known about the risk factors. Advanced SSc lung complications may accompany LVDD. METHOD: We conducted a cross-sectional study of 300 SSc outpatients with and without LVDD, seen between May 2012 and May 2014, and performed univariate and multivariate regression analyses to determine clinical factors associated with LVDD...
September 16, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27601074/troponin-i-and-echocardiography-in-patients-with-systemic-sclerosis-and-matched-population-controls
#16
A Nordin, E Svenungsson, L Björnådal, K Elvin, A Larsson, K Jensen-Urstad
OBJECTIVES: Cardiac manifestations in systemic sclerosis (SSc) are associated with poor prognosis. Few studies have investigated cardiac troponins in SSc. We studied the relationships between echocardiographic abnormalities, cardiac biomarkers, and disease manifestations in a population-based cohort of patients with SSc and controls. METHOD: The study comprised 110 patients with SSc and 105 age- and sex-matched population-based controls. We examined ventricular function, heart valves, and estimated pulmonary arterial pressure (ePAP) by echocardiography in all participants...
September 7, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27600931/no-diagnostic-utility-of-antibody-patterns-against-klebsiella-pneumoniae-capsular-serotypes-in-patients-with-axial-spondyloarthritis-vs-patients-with-non-specific-low-back-pain-a-cross-sectional-study
#17
L T Hermansen, A G Loft, A A Christiansen, H L Munk, L Gilbert, A G Jurik, B Arnbak, C Manniche, U Weber, M Østergaard, S J Pedersen, T Barington, P Junker, K Hørslev-Petersen, O Hendricks
OBJECTIVES: To investigate whether antibody response patterns against Klebsiella pneumoniae capsular serotypes can discriminate patients with axial spondyloarthritis (axSpA) from patients with non-specific low back pain (LBP). METHOD: Immunoglobulin (Ig)G and IgA antibodies against K. pneumoniae capsular serotypes K2, K26, K36, and K50 were measured, and antibody seropositivity compared between groups and analysed for patient correlation in five different groups: (a) 96 patients fulfilling the Assessment of SpondyloArthritis International Society (ASAS) classification criteria for axSpA; (b) 38 patients with either a positive magnetic resonance imaging (MRI) scan as defined by ASAS or a positive human leucocyte antigen (HLA)-B27 status plus one clinical SpA feature, characterized as 'non-axSpA'; (c) 82 non-specific LBP patients; (d) 40 healthy blood donors and (e) 43 patients with diagnosed ankylosing spondylitis (AS) served as the negative and positive control groups...
September 7, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27800696/reviewer-acknowledgement-2015-2016
#18
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27800695/erratum
#19
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27800694/author-acknowledgement-2016
#20
(no author information available yet)
No abstract text is available yet for this article.
November 2016: Scandinavian Journal of Rheumatology
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