Read by QxMD icon Read

Journal of Medical Primatology

Aman Dev Moudgil, Lachhman Das Singla
INTRODUCTION: This study aimed to assess Trichuris species infection and evaluate the anthelmintic efficacy of fenbendazole and ivermectin against natural trichurid infections in non-human primates (NHPs), kept at Mahendra Chaudhury (MC) Zoological Park, Chhatbir, India. MATERIALS AND METHODS: Molecular confirmation of Trichuris infection was carried out using polymerase chain reaction targeting internal transcribed spacer sequences, and anthelmintic efficacy was assessed by fecal egg count reduction test, respectively...
July 6, 2018: Journal of Medical Primatology
Sreetharan Kanthaswamy, Robert F Oldt, Jillian Ng, David Glenn Smith, Melween I Martínez, Carlos A Sariol
BACKGROUND: Knowledge of major histocompatibility complex (MHC) composition and distribution in rhesus macaque colonies is critical for management strategies that maximize the utility of this model for biomedical research. METHODS: Variation within the Mamu-A and Mamu-B (class I) and DRB, DQA/B, and DPA/B (class II) regions of 379 animals from the Caribbean Primate Research Center's (CPRC) specific pathogen free (SPF) colony was examined using massively parallel sequencing...
July 4, 2018: Journal of Medical Primatology
Ov Daniel Slayden, Francis Kathryn E Friason, Kise Rosen Bond, Emily Cathleen Mishler
BACKGROUND: Macaques are outstanding animal models for the development of new contraceptives. In women, progestin-only contraceptives often fail to block ovulation and are believed to act by altering cervix physiology. Herein, we assessed oviductal glycoprotein 1 (OVGP1) in the macaque cervix as a marker for progestogen action. MATERIALS: Rhesus macaques were treated with estradiol (E2 ), E2 plus progesterone (P), and E2 plus levonorgestrel (LNG), a contraceptive progestin...
July 4, 2018: Journal of Medical Primatology
Hillary F Huber, McKenna M Considine, Susan Jenkins, Cun Li, Peter W Nathanielsz
We investigated menstrual cycles in intrauterine growth restricted (IUGR, 7-10 years, n = 8) and age-matched control (n = 10) baboons. Cycle duration and plasma anti-Mullerian hormone were similar. IUGR spent more days per cycle swollen and had elevated early morning fasted serum cortisol, suggesting normal fertility in the presence of increased psychosocial stress.
June 29, 2018: Journal of Medical Primatology
Herlandes Penha Tinoco, Maria Elvira Loyola Teixeira da Costa, Angela Tinoco Pessanha, Carlyle Mendes Coelho, Tatiane Furtado de Carvalho, Juliana Pinto da Silva Mol, Agostinho Gonçalves Viana, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara, Renato Lima Santos
A 2-year-old captive gorilla (Gorilla gorilla gorilla) was diagnosed with visceral leishmaniasis in Brazil, and treated with a single dose of liposomal amphotericin B, which resulted in clinical cure. This is the first report of visceral leishmaniasis in gorillas, and the first reported liposomal amphotericin B treatment in great apes.
June 29, 2018: Journal of Medical Primatology
B Goldschmidt, C A A Lopes, F Resende, T A Pissinatti, D C Toledo, B C S Meireles, N F G Cordeiro
BACKGROUND: The taxonomic classification of squirrel monkeys is often controversial issue offering many different information. The classification of captive animals is difficult due to the phenotypic similarities between the presented species, which is observed mainly in coat coloration. METHODS: The objective of this study was to analyze the chromosome pattern of one squirrel monkey with off standard physical characteristics, which is kept in the Laboratory Animals Breeding Center in Rio de Janeiro State, Brazil, and try to establish some correlations...
June 29, 2018: Journal of Medical Primatology
Juan Fernando Vélez-García, Jorge Eduardo Duque-Parra, John Barco-Ríos
The gross anatomy of the palmaris longus muscle in 12 specimens of Saguinus leucopus was studied by dissection. This muscle was constant and unipennate, originated in the medial epicondyle of the humerus; inserted onto flexor retinaculum and palmar aponeurosis; and innerved by the median nerve, and in one case, together with the ulnar nerve. This is the first report of double innervation for this muscle in primates.
June 29, 2018: Journal of Medical Primatology
Alicia M Rich, Michael D Wasserman, Caroline Deimel, Scott K Breeden, Frederika Kaestle, Kevin D Hunt
BACKGROUND: We present 3 likely cases of testicular dysgenesis syndrome (TDS) within a community of chimpanzees (Pan troglodytes schweinfurthii). We tested whether genetic drift may be the culprit, as a genetic cause has been suspected to account for TDS among other wildlife. METHODS: We successfully sequenced a 367-bp segment spanning the first hypervariable region within the D-loop of the mitochondrial genome for 78 DNA samples. RESULTS: We found 24 polymorphic sequence sites consisting of 7 singletons and 17 parsimony informative sites...
May 25, 2018: Journal of Medical Primatology
Boris A Lapin, Zinaida V Shevtsova
The data characterizing spontaneous infections of Old World monkeys: measles, poliomyelitis, hepatitis A (HPA), encephalomyocarditis, coronavirus infection, simian hemorrhagic fever (SHF), are presented. The experimental infections were reproduced with the isolated pathogens. On these models, pathogenesis and epidemiology of these diseases were studied. The efficiency of poliomyelitis, measles and HPA vaccines is shown. The priority of data on the discovery of earlier unknown disease-SHF and "Sukhumi" virus-are emphasized...
May 25, 2018: Journal of Medical Primatology
Lydia E O Light, Thad Q Bartlett, Annica Poyas, Mark J Nijland, Hillary F Huber, Cun Li, Kate Keenan, Peter W Nathanielsz
BACKGROUND: We hypothesized that maternal nutrient restriction (NR) would increase activity and behavioral indicators of anxiety (self-directed behaviors, SDBs) in captive baboons (Papio sp.) and result in more protective maternal styles. METHODS: Our study included 19 adult female baboons. Seven females ate ad libitum (control group), and eight females ate 30% less (NR group) and were observed through pregnancy and lactation. RESULTS: Control females engage in higher rates of SDB than NR females overall (P ≤ ...
May 11, 2018: Journal of Medical Primatology
Bokyeong Ryu, Kyung-Yeon Eo, Ja-Jun Jang, C-Yoon Kim, Ji Min Lee, Hanseul Oh, Ukjin Kim, Jin Kim, Hyun-Ho Lee, Young-Mok Jung, Jae-Hak Park
We describe the first case of biliary cirrhosis in Japanese macaque. Clinical signs had not been detected. The liver was nodular. Histopathologically, portal-to-portal pattern of fibrosis might have indicated chronic cholestasis. Fibrotic septa were infiltrated with inflammatory cells. Therefore, this case could be diagnosed as active incomplete biliary cirrhosis.
May 4, 2018: Journal of Medical Primatology
Hanseul Oh, Kyung-Yeon Eo, Sanjeev Gumber, Jung Joo Hong, C-Yoon Kim, Hyun-Ho Lee, Young-Mok Jung, Jin Kim, Gyu-Whan Whang, Ji-Min Lee, Yong-Gu Yeo, Bokyeong Ryu, Ji-Sook Ryu, Seul-Kee Lee, Ukjin Kim, Sin-Geun Kang, Jae-Hak Park
BACKGROUND: Toxoplasma gondii (T. gondii) is an intracellular protozoan parasite that can infect warm-blooded animals including humans. New World monkeys, such as squirrel monkeys, are more susceptible to T. gondii than Old World monkeys, often developing fatal disease. METHODS: In this study, seven of thirteen dead squirrel monkeys at Seoul Grand Park were tested to find the cause of sudden death. RESULTS: The main histopathological findings included interstitial pneumonia, necrotizing hepatitis, and splenitis...
April 30, 2018: Journal of Medical Primatology
Allison Mustonen, Olga Gonzalez, Elda Mendoza, Shyamesh Kumar, Edward J Dick
BACKGROUND: Uremic encephalopathy is uncommon yet is one of the most severe complications of renal failure. We present a case of acute renal failure and associated cerebral and vascular lesions consistent with uremic encephalopathy in a rhesus macaque (Macaca mulatta). METHODS: A 14-year-old, female, specific-pathogen-free rhesus macaque presented in lateral recumbency, obtunded, severely dehydrated, and hypothermic, with severe azotemia, mild hyponatremia, hypokalemia, hypochloremia, increased anion gap, and hypercholesterolemia...
April 25, 2018: Journal of Medical Primatology
Thais Eleonora Madeira Buti, Tatiana Kugelmeier, Gisela Sobral, Priscila Viau Furtado, Dafne do Valle Dutra de Andrade Neves, Claudio Alvarenga de Oliveira
BACKGROUND: The advent of non-invasive methods provides a powerful alternative to stress studies as the use of stressful handling techniques is no longer needed. However, many factors influence hormone metabolism such as sex, diet, and metabolic rate. Thus, validation should be species- and matrix-specific. METHODS: To assess stress response in brown howler monkeys Alouatta clamitans, we adopted an ACTH challenge test and parallelism to provide physiological and laboratorial validation...
April 25, 2018: Journal of Medical Primatology
Charon de Villiers
BACKGROUND: It is generally accepted that non-human primates (NHP) represent the model of choice for integrative studies of testicular function and endocrine control. However, there are many species-specific differences that necessitate identification prior to the selection of an appropriate model for these studies. In an NHP breeding facility, this opportunity of selection is usually presented during breeding periods when it is crucial to determine which individuals should be maintained as breeders...
April 25, 2018: Journal of Medical Primatology
Jaclyn R Steinbach, Jamus MacGuire, Shu Chang, Elizabeth Dierks, Gordon S Roble
BACKGROUND: Retrospective analysis of post-operative vomiting (POV) in non-human primates at our institution was 11%. Based on this additional risk factor for post-operative complications, we aimed to eliminate or decrease POV by adding an antiemetic, maropitant citrate, to the pre-medication protocol. METHODS: Retrospective and prospective data were collected over a 5-year period from 46 macaques of two species during 155 procedures. Additionally, blood was collected from five Macaca mulatta to perform a pharmacokinetic analysis...
June 2018: Journal of Medical Primatology
Kimberly D Spradling-Reeves, Jeremy P Glenn, Kenneth J Lange, Natalia Kuhn, Jacqueline J Coalson, Mark J Nijland, Cun Li, Peter W Nathanielsz, Laura A Cox
BACKGROUND: Little is known about the repertoire of non-human primate kidney genes expressed throughout development. The present work establishes an understanding of the primate renal transcriptome during fetal development in the context of renal maturation. METHODS: The baboon kidney transcriptome was characterized at 60-day gestation (DG), 90 DG, 125 DG, 140 DG, 160 DG and adulthood (6-12 years) using gene arrays and validated by QRT-PCR. Pathway and cluster analyses were used to characterize gene expression in the context of biological pathways...
June 2018: Journal of Medical Primatology
J Díaz-Delgado, T C Sanches, C S Cirqueira, A A C Coimbra, J M Guerra, V Olivares, C Di Loretto, R A Ressio, S Iglezias, N C C A Fernandes, C Kanamura, K R Groch, J L Catão-Dias
Cutaneous neoplasia is common in non-human primates. We describe the gross and microscopic features of multicentric cutaneous keratoacanthomas in a free-living marmoset (Callithrix sp.). Immunohistochemistry for human papillomavirus and herpes simplex virus type I and simplex virus type II was negative. Keratoacanthomas should be included in the differential diagnosis for cutaneous masses in non-human primates.
June 2018: Journal of Medical Primatology
Yasuhiro Uno, Shotaro Uehara, Hassan M D Mahadhi, Kayoko Ohura, Masakiyo Hosokawa, Teruko Imai
BACKGROUND: Butyrylcholinesterase (BChE), an enzyme essential for drug metabolism, has been investigated as antidotes against organophosphorus nerve agents, and the efficacy and safety have been studied in cynomolgus macaques. BChE polymorphisms partly account for variable BChE activities among individuals in humans, but have not been investigated in cynomolgus macaques. METHODS: Molecular characterization was carried out by analyzing primary sequence, gene, tissue expression, and genetic variants...
June 2018: Journal of Medical Primatology
Braulio Hernández-Godínez, Adrián Poblano, Herlinda Bonilla-Jaime, Marcela Artega-Silva, Stephanie Sánchez-Torres, Rodrigo Mondragón-Lozano, Alejandra Ibáñez-Contreras
BACKGROUND: Somatosensory evoked potentials (SEPs) make it possible to obtain functional data on the activity of somatosensory pathway. OBJECTIVE: To evaluate the ontogeny of electrical nerve conduction in male rhesus monkeys using SEPs in correlation with the development of the musculoskeletal system based on somatometry and musculoskeletal enzymes. METHODS: Somatosensory evoked potentials of the medial and tibial nerves were performed, and somatometric measurements were obtained: total length, arm and forearm length, and thigh and calf length...
June 2018: Journal of Medical Primatology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"