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Nigerian Medical Journal: Journal of the Nigeria Medical Association

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https://www.readbyqxmd.com/read/27942104/serum-thyroid-stimulating-hormone-level-and-relation-with-size-of-hippocampus-in-patients-with-mild-cognitive-disorders
#1
Mohammad-Hossein Daghighi, Masoud Poureisa, Pegah Ahmadi, Mahmoud Reshadatjoo, Sahar Golestani, Mohammad Naghavi-Behzad, Farid Karkon-Shayan
BACKGROUND: Cognitive disorders and dementia are common problems, and Alzheimer's disease is one of the major leading causes of death worldwide. Thyroid hormone disorders as a common problem effect on hippocampus size which as a prognostic factor in dementia. The aim of the present study was to investigate the relationship between serum thyroid-stimulating hormone (TSH) level and the size of hippocampus in patients with mild cognitive disorders. MATERIALS AND METHODS: In a descriptive-analytical study, 41 patients with symptoms of mild cognitive disorders whom referred to take the brain magnetic resonance image (MRI) in a radiology center under the direction of Tabriz University of Medical Sciences (Tabriz, Iran) were evaluated...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942103/gentamicin-mediated-ototoxicity-and-nephrotoxicity-a-clinical-trial-study
#2
Parviz Saleh, Shamsi Abbasalizadeh, Saman Rezaeian, Mohammad Naghavi-Behzad, Reza Piri, Hojjat Hossein Pourfeizi
BACKGROUND: Aminoglycosides and mainly gentamicin are the most important antimicrobial agents. Two different methods of administration exist: Single and multiple doses. There has always been a controversy about the less harmful administration method, to minimize adverse effects of gentamicin - deafness and renal insufficiency. In this study, it was aimed to compare two different methods of administration to figure out the least harmful treatment method. MATERIALS AND METHODS: In a clinical study, eighty patients aged 12-55 years who were admitted with sepsis syndrome were included in the study; they were divided into two groups: The first group received single-dose treatment (5 mg/kg) whereas the second group was treated with multiple doses (1...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942102/quality-of-acute-asthma-care-in-two-tertiary-hospitals-in-a-state-in-south-western-nigeria-a-report-of-clinical-audit
#3
Olufemi Olumuyiwa Desalu, Adekunle Olatayo Adeoti, Olarinde Jeffrey Ogunmola, Joseph Olusesan Fadare, Tolutope Fasanmi Kolawole
BACKGROUND: To audit the quality of acute asthma care in two tertiary hospitals in a state in the southwestern region of Nigeria and to compare the clinical practice against the recommendations of the Global Initiative for Asthma (GINA) guideline. PATIENTS AND METHODS: We carried out a retrospective analysis of 101 patients who presented with acute exacerbation of asthma to the hospital between November 2010 and October 2015. RESULTS: Majority of the cases were females (66...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942101/unintended-pregnancy-among-antenatal-women-in-a-tertiary-hospital-in-north-central-nigeria
#4
Teddy E Agida, Godwin O Akaba, Bissalla A Ekele, Francis Adebayo
BACKGROUND: Unintended pregnancy is a pregnancy that is either unwanted or mistimed. The objectives of this study were to determine the prevalence of unintended pregnancy as well as to document the determinant factors among pregnant women attending antenatal clinic at the University of Abuja Teaching Hospital, Gwagwalada, Abuja, Nigeria. MATERIALS AND METHODS: This was a descriptive, cross-sectional study of 300 women attending the antenatal clinic of the Teaching Hospital...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942100/abdominal-wall-endometrioma-our-experience-in-vladimir-russia
#5
Mahir Gachabayov, Roman Horta, Dmitriy Afanasyev, Timur Gilyazov
BACKGROUND: Endometriosis is defined as an estrogen-dependent, benign inflammatory disease characterized by the presence of ectopic endometrial implants. Abdominal wall endometrioma (AWE) being a rare entity is a benign tumor defined as ectopic functional, endometrial tissue located in the abdominal wall. SUBJECTS AND METHODS: A retrospective study of 23 female patients treated with AWE in four departments of three centers in Vladimir city, Russia, from January 2010 to December 2014 was performed...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942099/study-of-pentoxifylline-effects-on-motility-and-viability-of-spermatozoa-from-infertile-asthenozoospermic-males
#6
Aliye Ghasemzadeh, Farid Karkon-Shayan, Solmaz Yousefzadeh, Mohammad Naghavi-Behzad, Kobra Hamdi
BACKGROUND: The quality of semen is one of the major parameters in male infertility. Pentoxifylline, a methylxanthine derivative, is an agent primarily used in the treatment of intermittent claudication and other vascular disorders. Studies have shown that pentoxifylline enhances the quality and quantity of sperms. In this study, we have investigated the in vitro effects of pentoxifylline on viability and motility of spermatozoa in samples of infertile oligoasthenozoospermic males. MATERIALS AND METHODS: In this observer-blinded clinical trial, semen samples of 25 infertile oligoasthenozoospermic males were collected in Alzahra Educational Medical Center of Tabriz University of Medical Sciences from August 2010 to August 2012...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942098/obstetric-predictors-of-hypertension-a-cross-sectional-study-of-women-attending-the-postnatal-clinic-of-jos-university-teaching-hospital
#7
Hadiza A Agbo, Basil N Okeahialam, Patrick H Daru
BACKGROUND: Hypertensive disease in pregnancy (HDP) accounts for high mother and child morbi-mortality and predict future cardiometabolic diseases. This study aimed to identify obstetric predictors of HDP needing preventive action to reduce its consequences; when women present to antenatal clinic (ANC). MATERIALS AND METHODS: Cross-sectional descriptive this was an Interviewer-administered semi-structured questionnaire-based study of the anthropometric, and blood pressure measurementsin attendees at the postnatal clinic (PNC) of Jos University with ANC records...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942097/sociodemographic-profiles-and-use-dynamics-of-jadelle-levonorgestrel-implants-in-jos-nigeria
#8
V C Pam, J T Mutihir, D D Nyango, I Shambe, C O Egbodo, J A Karshima
BACKGROUND: Contraceptive implants (including Jadelle) are highly effective, safe, and easy to use and have a long duration of action. They do not interfere with intercourse with immediate return to fertility after removal. However, disruption of the menstrual bleeding pattern is almost inevitable and coercive prescription may be a problem because insertion and removal of implants are provider dependent. The objective of this study was to determine the sociodemographic profiles of acceptors of Jadelle and the reasons for discontinuation in Jos, Nigeria...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27942096/dietary-practices-and-nutritional-status-of-under-five-children-in-rural-and-urban-communities-of-lagos-state-nigeria
#9
Idowu O Senbanjo, Ibiyemi O Olayiwola, Wasiu A O Afolabi
BACKGROUND: Evidence shows that urban children generally have a better nutritional status than their rural counterparts. However, data establishing whether this difference in prevalence of undernutrition could be ascribed to difference in dietary practices are few. OBJECTIVE: The aim of this study was to compare dietary practices and nutritional status of children in rural and urban communities of Lagos State, Nigeria. METHODS: This was a comparative-analytical study conducted using the multistage sampling technique to select the study cases...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833251/cross-sectional-study-on-the-obstetric-performance-of-primigravidae-in-a-teaching-hospital-in-lagos-nigeria
#10
Kehinde Sharafadeen Okunade, Halimat Okunola, Lawal Oyeneyin, Fatimah N Habeeb-Adeyemi
BACKGROUND: A woman carrying her first pregnancy is starting a new life, and this is a crucial time in her obstetric career. This study was aimed to compare the obstetric performance of primigravidae to that of the multigravidae with a view to suggesting ways of preventing the associated complications. PATIENTS AND METHODS: The study was a cross-sectional case-control study carried out among women who delivered in the study center over a year period. Relevant data of primigravid parturients who delivered in the hospital were retrieved from the labor ward register, and an equal number of multigravidae who delivered during the same study were selected by simple random sampling as the control group...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833250/cytohistological-discordance-on-gastrointestinal-brushings-facts-unfolded
#11
Ruchita Tyagi, Jagpal Kaur, Gursheen Kaur, Pavneet Kaur Selhi, Harpreet Kaur Puri, Neena Sood
INTRODUCTION: Brush cytology is a rapid, cost-effective, and reliable tool to diagnose gastrointestinal tract (GIT) lesions in low-resource settings. Most of the studies on GIT brushings have focused on upper GI lesions. We have studied the diagnostic accuracy of brush cytology in the entire length of GIT and correlated the cytological diagnosis with histopathology. The aim of this study is to study diagnostic utility of brush cytology of GIT lesions in the context of correlation with biopsy and study the factors responsible for cytohistological discordance...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833249/quality-of-life-and-associated-factors-among-poststroke-clinic-attendees-at-a-university-teaching-hospital-in-nigeria
#12
Osunwale Dahunsi Oni, Olatunji F Aina, Francis I Ojini, Victor O Olisah
BACKGROUND: Quality of life (QOL) measures are effective in quantifying disease burden after stroke, more so than levels of debility. The objective of this study is to determine QOL and associated factors of stroke survivors in Lagos, Nigeria. MATERIALS AND METHODS: Seventy stroke survivors (study sample) and seventy stable hypertensive patients (control sample) attending clinics at a Nigerian hospital were recruited for the study. Respondents were assessed using sociodemographic/clinical questionnaires, modified mini-mental state examination, modified Rankin Scale, schedule for clinical assessment in neuropsychiatry, and World Health Organization-QOL-BREF...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833248/genital-prolapse-a-5-year-review-at-federal-medical-centre-umuahia-southeastern-nigeria
#13
Obinna Izuchukwu Oraekwe, Maduabuchi Amagh Udensi, Kelechi Chiemela Nwachukwu, Uka Kalu Okali
BACKGROUND: Genital prolapse is an important cause of morbidity among postmenopausal and multiparous women especially in our environment where a high premium is placed on large family size. This study was done to determine the prevalence, risk factors, clinical presentation, and management options of genital prolapse. PATIENTS AND METHODS: Data of those diagnosed with genital prolapse were retrieved from records in the clinic, wards, theater, and from patients' folders in the medical records department...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833247/malignant-tumors-of-the-larynx-clinicopathologic-profile-and-implication-for-late-disease-presentation
#14
Ayotunde James Fasunla, Oluwole Agboola Ogundoyin, Paul Adekunle Onakoya, Onyekwere George Nwaorgu
BACKGROUND: Malignant laryngeal tumors are uncommon. Late presentation of the disease may worsen management outcomes. We described the epidemiologic, clinicopathologic profile, and management outcomes of laryngeal tumors in a tertiary health institution in Nigeria. MATERIALS AND METHODS: An 11-year retrospective review of medical records of patients managed for malignant laryngeal tumor at the University College Hospital, Ibadan, Nigeria, was performed. RESULTS: There were 97 patients comprising 74 (76...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833246/effect-of-submucosal-or-oral-administration-of-prednisolone-on-postoperative-sequelae-following-surgical-extraction-of-impacted-mandibular-third-molar-a-randomized-controlled-study
#15
Adebayo Aremu Ibikunle, Wasiu Lanre Adeyemo, Akinola Ladipo Ladeinde
BACKGROUND: The aim of the study was to evaluate the effect of preoperatively administered submucosal and oral prednisolone on postoperative pain, facial swelling, and trismus following third molar surgery. PATIENTS AND METHODS: This was a randomized controlled trial in which subjects were randomly distributed into three groups. Group A consisted of subjects who received 40 mg oral prednisolone; Group B consisted of subjects who received 40 mg submucosal injection of prednisolone while Group C consisted of subjects who did not receive prednisolone...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833245/buccal-mucosal-graft-urethroplasty-for-proximal-bulbar-urethral-stricture-a-revisit-of-the-surgical-technique-and-analysis-of-eleven-consecutive-cases
#16
Irekpita Eshiobo, Esezobor Ehizomen, F Omosofe, V Onuora
BACKGROUND: Urethral stricture disease is prevalent, and many surgical techniques have been developed to treat it. Currently, urethroplasty for bulbar strictures implies ventral or dorsal stricturotomy and a buccal mucosa graft (BMG) patch. OBJECTIVE: To describe the surgical approach of the ventral patch BMG urethroplasty for proximal bulbar urethral stricture and to analyze 11 consecutive cases for whom the technique was used. PATIENTS AND METHODS: The diagnosis of urethral stricture was confirmed with a combined retrograde urethrography and micturating cystourethrography...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833244/nigeria-s-national-health-act-an-assessment-of-health-professionals-knowledge-and-perception
#17
Osahon Enabulele, Joan Emien Enabulele
BACKGROUND: Nigeria's National Health Act 2014 (NHA 2014) was signed into law on October 31, 2014. It provides a legal framework for the regulation, development, and management of Nigeria's Health System. This study assessed the knowledge and perception of the NHA 2014 by health professionals. MATERIALS AND METHODS: This was a descriptive, cross-sectional, questionnaire-based study conducted in December 2015, in Ota, Ogun State, Nigeria. Data entry and analysis were done using the Statistical Package for the Social Sciences version 16 (IBM SPSS, Chicago, IL, USA) statistical software, with Pearson's Chi-square, which is used to determine the associations between variables...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833243/short-term-effects-of-lovastatin-therapy-on-proteinuria-of-type-2-diabetic-nephropathy-a-clinical-trial-study
#18
Alireza Sadighi, Javid Safa, Amir-Mansour Vatankhah, Sona Ghorashi, Aida Aharilahagh, Sina Davari-Farid, Ourmaan Nezami-Nargabad, Mohammad Naghavi-Behzad, Reza Piri, Parinaz Pishahang, Savalan Babapoor-Farrokhran, Sanam Fakour, Nastaran Ghodratnezhad-Azar
BACKGROUND: Diabetic nephropathy (DN) is characterized by albuminuria, hypertension, and a progressive decline in glomerular filtration rate. The 3-hydroxy-3-methylglutaryl coenzyme A is a well-known agent that is active in lowering total plasma and low-density lipoprotein cholesterol (LDL-C) levels in cases with hypercholesterolemia. Hence, in this study, proteinuria changes at the beginning and after the withdrawal of lovastatin in patients with type 2 DN (T2DN) were studied. MATERIALS AND METHODS: Lovastatin was administered for thirty male patients with T2DN and then was withdrawn...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630391/erratum-serum-copper-and-zinc-levels-in-preeclamptic-nigerian-women
#19
(no author information available yet)
[This corrects the article on p. 184 in vol. 57.].
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630390/postexposure-prophylaxis-for-lassa-fever-experience-from-a-recent-outbreak-in-nigeria
#20
Samson E Isa, Attah Okwute, Kelly O Iraoyah, Shehu Y Nathan, Gomerep S Simji, Mark O Okolo, Joseph Anejo-Okopi, Daria Spicola, Daisy E Isa
BACKGROUND: Secondary transmission of Lassa fever (LF) occurs in the community and in health-care facilities, and is associated with high fatality in Nigeria. We investigated the role of oral ribavirin postexposure prophylaxis (orPEP) in preventing LF among the primary contacts of confirmed cases from December 2015 to March 2016. MATERIALS AND METHODS: Epidemiological and clinical data of LF contacts were prospectively collected. However, information regarding ribavirin adverse effects (AEs) were collected retrospectively through a telephone interview...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
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