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Nigerian Medical Journal: Journal of the Nigeria Medical Association

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https://www.readbyqxmd.com/read/27833251/cross-sectional-study-on-the-obstetric-performance-of-primigravidae-in-a-teaching-hospital-in-lagos-nigeria
#1
Kehinde Sharafadeen Okunade, Halimat Okunola, Lawal Oyeneyin, Fatimah N Habeeb-Adeyemi
BACKGROUND: A woman carrying her first pregnancy is starting a new life, and this is a crucial time in her obstetric career. This study was aimed to compare the obstetric performance of primigravidae to that of the multigravidae with a view to suggesting ways of preventing the associated complications. PATIENTS AND METHODS: The study was a cross-sectional case-control study carried out among women who delivered in the study center over a year period. Relevant data of primigravid parturients who delivered in the hospital were retrieved from the labor ward register, and an equal number of multigravidae who delivered during the same study were selected by simple random sampling as the control group...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833250/cytohistological-discordance-on-gastrointestinal-brushings-facts-unfolded
#2
Ruchita Tyagi, Jagpal Kaur, Gursheen Kaur, Pavneet Kaur Selhi, Harpreet Kaur Puri, Neena Sood
INTRODUCTION: Brush cytology is a rapid, cost-effective, and reliable tool to diagnose gastrointestinal tract (GIT) lesions in low-resource settings. Most of the studies on GIT brushings have focused on upper GI lesions. We have studied the diagnostic accuracy of brush cytology in the entire length of GIT and correlated the cytological diagnosis with histopathology. The aim of this study is to study diagnostic utility of brush cytology of GIT lesions in the context of correlation with biopsy and study the factors responsible for cytohistological discordance...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833249/quality-of-life-and-associated-factors-among-poststroke-clinic-attendees-at-a-university-teaching-hospital-in-nigeria
#3
Osunwale Dahunsi Oni, Olatunji F Aina, Francis I Ojini, Victor O Olisah
BACKGROUND: Quality of life (QOL) measures are effective in quantifying disease burden after stroke, more so than levels of debility. The objective of this study is to determine QOL and associated factors of stroke survivors in Lagos, Nigeria. MATERIALS AND METHODS: Seventy stroke survivors (study sample) and seventy stable hypertensive patients (control sample) attending clinics at a Nigerian hospital were recruited for the study. Respondents were assessed using sociodemographic/clinical questionnaires, modified mini-mental state examination, modified Rankin Scale, schedule for clinical assessment in neuropsychiatry, and World Health Organization-QOL-BREF...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833248/genital-prolapse-a-5-year-review-at-federal-medical-centre-umuahia-southeastern-nigeria
#4
Obinna Izuchukwu Oraekwe, Maduabuchi Amagh Udensi, Kelechi Chiemela Nwachukwu, Uka Kalu Okali
BACKGROUND: Genital prolapse is an important cause of morbidity among postmenopausal and multiparous women especially in our environment where a high premium is placed on large family size. This study was done to determine the prevalence, risk factors, clinical presentation, and management options of genital prolapse. PATIENTS AND METHODS: Data of those diagnosed with genital prolapse were retrieved from records in the clinic, wards, theater, and from patients' folders in the medical records department...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833247/malignant-tumors-of-the-larynx-clinicopathologic-profile-and-implication-for-late-disease-presentation
#5
Ayotunde James Fasunla, Oluwole Agboola Ogundoyin, Paul Adekunle Onakoya, Onyekwere George Nwaorgu
BACKGROUND: Malignant laryngeal tumors are uncommon. Late presentation of the disease may worsen management outcomes. We described the epidemiologic, clinicopathologic profile, and management outcomes of laryngeal tumors in a tertiary health institution in Nigeria. MATERIALS AND METHODS: An 11-year retrospective review of medical records of patients managed for malignant laryngeal tumor at the University College Hospital, Ibadan, Nigeria, was performed. RESULTS: There were 97 patients comprising 74 (76...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833246/effect-of-submucosal-or-oral-administration-of-prednisolone-on-postoperative-sequelae-following-surgical-extraction-of-impacted-mandibular-third-molar-a-randomized-controlled-study
#6
Adebayo Aremu Ibikunle, Wasiu Lanre Adeyemo, Akinola Ladipo Ladeinde
BACKGROUND: The aim of the study was to evaluate the effect of preoperatively administered submucosal and oral prednisolone on postoperative pain, facial swelling, and trismus following third molar surgery. PATIENTS AND METHODS: This was a randomized controlled trial in which subjects were randomly distributed into three groups. Group A consisted of subjects who received 40 mg oral prednisolone; Group B consisted of subjects who received 40 mg submucosal injection of prednisolone while Group C consisted of subjects who did not receive prednisolone...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833245/buccal-mucosal-graft-urethroplasty-for-proximal-bulbar-urethral-stricture-a-revisit-of-the-surgical-technique-and-analysis-of-eleven-consecutive-cases
#7
Irekpita Eshiobo, Esezobor Ehizomen, F Omosofe, V Onuora
BACKGROUND: Urethral stricture disease is prevalent, and many surgical techniques have been developed to treat it. Currently, urethroplasty for bulbar strictures implies ventral or dorsal stricturotomy and a buccal mucosa graft (BMG) patch. OBJECTIVE: To describe the surgical approach of the ventral patch BMG urethroplasty for proximal bulbar urethral stricture and to analyze 11 consecutive cases for whom the technique was used. PATIENTS AND METHODS: The diagnosis of urethral stricture was confirmed with a combined retrograde urethrography and micturating cystourethrography...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833244/nigeria-s-national-health-act-an-assessment-of-health-professionals-knowledge-and-perception
#8
Osahon Enabulele, Joan Emien Enabulele
BACKGROUND: Nigeria's National Health Act 2014 (NHA 2014) was signed into law on October 31, 2014. It provides a legal framework for the regulation, development, and management of Nigeria's Health System. This study assessed the knowledge and perception of the NHA 2014 by health professionals. MATERIALS AND METHODS: This was a descriptive, cross-sectional, questionnaire-based study conducted in December 2015, in Ota, Ogun State, Nigeria. Data entry and analysis were done using the Statistical Package for the Social Sciences version 16 (IBM SPSS, Chicago, IL, USA) statistical software, with Pearson's Chi-square, which is used to determine the associations between variables...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27833243/short-term-effects-of-lovastatin-therapy-on-proteinuria-of-type-2-diabetic-nephropathy-a-clinical-trial-study
#9
Alireza Sadighi, Javid Safa, Amir-Mansour Vatankhah, Sona Ghorashi, Aida Aharilahagh, Sina Davari-Farid, Ourmaan Nezami-Nargabad, Mohammad Naghavi-Behzad, Reza Piri, Parinaz Pishahang, Savalan Babapoor-Farrokhran, Sanam Fakour, Nastaran Ghodratnezhad-Azar
BACKGROUND: Diabetic nephropathy (DN) is characterized by albuminuria, hypertension, and a progressive decline in glomerular filtration rate. The 3-hydroxy-3-methylglutaryl coenzyme A is a well-known agent that is active in lowering total plasma and low-density lipoprotein cholesterol (LDL-C) levels in cases with hypercholesterolemia. Hence, in this study, proteinuria changes at the beginning and after the withdrawal of lovastatin in patients with type 2 DN (T2DN) were studied. MATERIALS AND METHODS: Lovastatin was administered for thirty male patients with T2DN and then was withdrawn...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630391/erratum-serum-copper-and-zinc-levels-in-preeclamptic-nigerian-women
#10
(no author information available yet)
[This corrects the article on p. 184 in vol. 57.].
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630390/postexposure-prophylaxis-for-lassa-fever-experience-from-a-recent-outbreak-in-nigeria
#11
Samson E Isa, Attah Okwute, Kelly O Iraoyah, Shehu Y Nathan, Gomerep S Simji, Mark O Okolo, Joseph Anejo-Okopi, Daria Spicola, Daisy E Isa
BACKGROUND: Secondary transmission of Lassa fever (LF) occurs in the community and in health-care facilities, and is associated with high fatality in Nigeria. We investigated the role of oral ribavirin postexposure prophylaxis (orPEP) in preventing LF among the primary contacts of confirmed cases from December 2015 to March 2016. MATERIALS AND METHODS: Epidemiological and clinical data of LF contacts were prospectively collected. However, information regarding ribavirin adverse effects (AEs) were collected retrospectively through a telephone interview...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630389/dna-methylation-analysis-of-secreted-frizzled-related-protein-2-gene-for-the-early-detection-of-colorectal-cancer-in-fecal-dna
#12
Hadi Babaei, Mohsen Mohammadi, Rasoul Salehi
BACKGROUND: The early detection of colorectal cancer (CRC) with high sensitivity screening is essential for the reduction of cancer-specific mortality. Abnormally methylated genes that are responsible for the pathogenesis of cancers can be used as biomarkers for the detection of CRC. The methylation status of the secreted frizzled-related protein 2 (SFRP2) gene was evaluated for their use as a marker in the noninvasive detection of CRC. MATERIALS AND METHODS: Methylation-specific polymerase chain reaction was performed to analyze the promoter CpG methylation of SFRP2 in the fecal DNA of 25 patients with CRC and 25 individuals exhibiting normal colonoscopy results...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630388/outcome-of-radical-retropubic-prostatectomy-at-the-lagos-state-university-teaching-hospital
#13
Stephen Odunayo Ikuerowo, Alaba Fredrick Doherty, Muftau Jimoh Bioku, Abimbola Ayodeji Abolarinwa, Adekunle Azeez Adebayo, Steves Olaide Oyeleke, Olufunmilade Akinfolarin Omisanjo
BACKGROUND: Prostate cancer is the most commonly diagnosed cancer in men in Nigeria and most cases present when the disease is already in an advanced stage. Radical prostatectomy for early prostate cancer is therefore not a commonly performed operation by urologists in Nigeria. We have had training and significant experience in radical retropubic prostatectomy. We, therefore, report the outcome of our initial experience. MATERIALS AND METHODS: We review the record of men with early prostate cancer who had radical retropubic prostatectomy in our institution from 2007 to 2015...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630387/evaluation-of-serum-level-of-tumor-necrosis-factor-alpha-and-interleukin-6-in-patients-with-congenital-heart-disease
#14
Noor Mohammad Noori, Maryam Nakhaee Moghaddam, Alireza Teimouri, Iraj Shahramian, Behrooz Keyvani
BACKGROUND: The objective of the study is to assess the levels of tumor necrosis factor-alpha (TNF-α) and interleukin-10 (IL-10) in patients with congenital heart diseases (CHDs) and control. PATIENTS AND METHODS: In this case-control study, sixty patients with CHD with ages of 1 month to 15 years and thirty healthy subjects were assessed. All objects measured in height, weight, age, sex, and body mass index (BMI). Patients diagnosed by echocardiography and patients' blood samples were 3 ml and taken in the catheterization laboratory through catheter and kept for 60 min at a room with normal temperature and separated serum has been held...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630386/evaluation-of-sexual-dimorphism-by-discriminant-function-analysis-of-toe-length-1t-5t-of-adult-igbo-populace-in-nigeria
#15
Stephen A Alabi, Blessing C Didia, Gabriel Sunday Oladipo, Eric O Aigbogun
BACKGROUND: Sex determination is an important and one of the foremost criteria in establishing the identity of an individual, and this is achieved by investigating various anatomical structures to establish sex discriminatory features. The present study conducted baseline data for the toe with a view of finding discriminatory sex characteristics. MATERIALS AND METHODS: A total of 420 subjects were studied by direct linear measurements of the toe length (big toe [1T] to the fifth toes [5T]) of both feet using a digital Vernier caliper with accuracy of 0...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630385/awareness-and-knowledge-of-national-school-health-policy-and-school-health-programme-among-public-secondary-school-teachers-in-ibadan-metropolis
#16
Taiwo A Obembe, Kayode O Osungbade, Oluwakemi M Ademokun
BACKGROUND: The awareness, knowledge, and involvement of teachers in the implementation of School Health Programme (SHP) in secondary schools are essential in ensuring the effectiveness and overall success of the School Health Policy. This study assessed the awareness and knowledge of teachers on SHP in Ibadan metropolis. METHODS: A descriptive cross-sectional study was carried out using a two-stage sampling technique to select 426 secondary school teachers across all the five Urban Local Government Areas (LGAs) in Ibadan metropolis by balloting...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630384/utility-of-a-single-mid-trimester-measurement-of-plasminogen-activator-type-1-and-fibronectin-to-predict-preeclampsia-in-pregnancy
#17
S O Ajibola, T A Adeyemo, B B Afolabi, A S Akanmu
BACKGROUND: Preeclampsia (PE) is the second most common cause of maternal death after obstetric hemorrhage in Africa, a resource-limited region. This study was designed to examine the potential usefulness of a single screening plasma plasminogen activator inhibitor-1 (PAI-1) and fibronectin (FN) level for the prediction of PE in pregnant women. MATERIALS AND METHODS: In a cohort of 180 pregnant women who were normotensive at baseline, venous blood samples were obtained before 20 weeks of gestation for the assay of plasma levels of PAI-1 and FN levels measured by enzyme-linked immunoassay technique...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630383/the-relationship-between-malaria-parasitemia-malaria-preventive-measures-and-average-birth-weight-of-babies-in-a-tertiary-facility-in-owerri-nigeria
#18
E E Idih, B U Ezem, E A Nzeribe, A O Onyegbule, B C Duru, C C Amajoyi
BACKGROUND: Despite the global efforts made to eradicate malaria, it continues to be a significant cause of morbidity and mortality in both neonates and the parturients. This study was done to determine the relationship between placental parasitemia, average neonatal birth weight and the relationship between the use of malaria preventive measures and the occurrence of placental parasitemia with the aim to improving maternal and neonatal outcome. PATIENTS AND METHODS: This cross-sectional study was done at the labor ward unit of the Federal Medical Center, Owerri, from December 2013 to May 2014...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630382/adult-intussusception-an-8-years-institutional-review
#19
Isaac Assam Udo, Emmanuel K Abudu, Felix Uduma
BACKGROUND: Intussusception is a rare cause of intestinal obstruction in adults. Its diagnosis could be elusive based solely on clinical features because of protean presentation. Supplementary imaging allows for preoperative diagnosis, early institution of definitive management, and a better clinical outcome. PATIENTS AND METHODS: Records of adults managed for intestinal obstruction by laparotomy in a surgical unit of a tertiary health facility were retrospectively examined...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27630381/the-effect-of-deoxyribonucleic-acid-extraction-methods-from-lymphoid-tissue-on-the-purity-content-and-amplifying-ability
#20
Hossein Ayatollahi, Mohammad Hadi Sadeghian, Mohammad Reza Keramati, Ali Ayatollahi, Arezoo Shajiei, Maryam Sheikhi, Samane Bakhshi
BACKGROUND: Nowadays, definitive diagnosis of numerous diseases is based on the genetic and molecular findings. Therefore, preparation of fundamental materials for these evaluations is necessary. Deoxyribonucleic acid (DNA) is the first material for the molecular pathology and genetic analysis, and better results need more pure DNA. Furthermore, higher concentration of achieved DNA causes better results and higher amplifying ability for subsequent steps. We aim to evaluate five DNA extraction methods to compare DNA intimacy including purity, concentration, and amplifying ability with each other...
July 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
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