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Veterinary Pathology

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https://www.readbyqxmd.com/read/28622497/feline-panleukopenia-virus-is-not-associated-with-myocarditis-or-endomyocardial-restrictive-cardiomyopathy-in-cats
#1
Laura McEndaffer, Alex Molesan, Hollis Erb, Kathleen Kelly
Canine parvovirus-2 (CPV-2) is nearly indistinguishable from feline panleukopenia virus (FPV) and is a well-known cause of viral myocarditis in young puppies; however, it is not known whether either FPV or CPV-2 naturally infects feline cardiomyocytes and causes myocarditis. Endomyocarditis (EMC) and left ventricular endomyocardial fibrosis (LVEF), clinically known as "endomyocardial restrictive cardiomyopathy," are important feline heart diseases suspected to have an infectious etiology. A continuum is suggested with EMC representing the acute reaction to an unknown infectious agent and LVEF the chronic manifestation of repair...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28622496/equine-hoof-canker-cell-proliferation-and-morphology
#2
V Apprich, T Licka, N Zipfl, A Tichy, C Gabriel
Hoof canker is described as progressive pododermatitis of the equine hoof with absent epidermal cornification and extensive proliferation of the dermal papillary body; however, in-depth research on the type of proliferative activity has not yet been reported. The aim of the present study was to determine cell-specific proliferation patterns together with morphological analysis of hoof canker tissue. Tissues removed during surgery from 19 horses presented for treatment of canker were compared with similar postmortem tissues of healthy hooves of 10 horses...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28622495/the-acvp-stp-coalition-for-veterinary-pathology-fellows-celebrates-32-new-training-positions
#3
Gary L Cockerell, Cory Brayton, Anne Barger, Brad Bolon
No abstract text is available yet for this article.
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28622494/laryngeal-neuropathy-in-adult-goats-with-copper-deficiency
#4
R F A Sousa, V M Almeida, J E Neto, C W A Nascimento, G X Medeiros, R M T Medeiros, F Riet-Correa, F S Mendonça
The aim of this study was to elucidate the cause of a neurological syndrome characterized by stridor in adult goats with clinical signs of copper deficiency. The main clinical signs consisted of apathy, emaciation, pale mucous membranes, mucous nasal discharge, dyspnea, severe achromotrichia, diffuse alopecia, torpor, ataxia, and stridor. When the goats were forced to move, the stridor increased. In a herd of 194 Toggenburg goats, 10 adult goats with clinical signs of copper deficiency were removed from the herd and divided into 2 groups: group 1, which consisted of 4 nannies and 1 buck with stridor, and group 2, which consisted of 4 nannies and 1 buck without stridor...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28622493/the-evolving-significance-and-future-relevance-of-the-impact-factor
#5
D K Meyerholz, H A Flaherty
No abstract text is available yet for this article.
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28622492/book-review-color-atlas-of-equine-pathology-color-atlas-of-equine-pathology-edited-by-buergelt-claus-d-piero-fabio-del-wiley-blackwell-new-york-ny-2014-isbn-9780470962848
#6
https://www.readbyqxmd.com/read/28622491/putting-the-idiopathic-back-into-porcine-idiopathic-vesicular-disease-setting-the-record-straight-on-reports-of-pivd-in-new-zealand
#7
K N Buckle, P C Bingham
No abstract text is available yet for this article.
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28622490/lawsonia-intracellularis-in-pigs-progression-of-lesions-and-involvement-of-apoptosis
#8
Roberto M C Guedes, Mariana A Machuca, Maria A Quiroga, Carlos E Real Pereira, Talita P Resende, Connie J Gebhart
The purpose of this study was to follow the progression of gross and histologic lesions and apoptosis events in Lawsonia intracellularis-infected enterocytes through the course of the disease, proliferative enteropathy (PE). Thirty 5-week-old pigs were divided into 2 groups: 20 challenged and 10 control animals. Groups of 3 pigs, 2 challenged and 1 control, were euthanized at 1, 3, 5, 8, 11, 15, 19, 24, 29, and 35 days after inoculation. Complete necropsies were performed with gross evaluation. Tissue samples from different sites of the gastrointestinal tract and other visceral organs were collected for routine histologic staining and for immunohistochemistry (IHC) for L...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28494706/ranid-herpesvirus-3-and-proliferative-dermatitis-in-free-ranging-wild-common-frogs-rana-temporaria
#9
F C Origgi, B R Schmidt, P Lohmann, P Otten, E Akdesir, V Gaschen, L Aguilar-Bultet, T Wahli, U Sattler, M H Stoffel
Amphibian pathogens are of current interest as contributors to the global decline of amphibians. However, compared with chytrid fungi and ranaviruses, herpesviruses have received relatively little attention. Two ranid herpesviruses have been described: namely, Ranid herpesvirus 1 (RHV1) and Ranid herpesvirus 2 (RHV2). This article describes the discovery and partial characterization of a novel virus tentatively named Ranid herpesvirus 3 (RHV3), a candidate member of the genus Batrachovirus in the family Alloherpesviridae...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28494704/endoscopic-cytology-for-the-diagnosis-of-chronic-enteritis-and-intestinal-lymphoma-in-dogs
#10
S Maeda, M Tsuboi, K Sakai, K Ohno, K Fukushima, H Kanemoto, S Hiyoshi-Kanemoto, Y Goto-Koshino, J K Chambers, T Yonezawa, K Uchida, N Matsuki
Although cytology is a rapid diagnostic procedure in dogs, the cytologic criteria of endoscopic biopsies for chronic enteritis and intestinal lymphoma are not well defined. An immediate diagnosis using cytology would benefit patients by enabling prompt initiation of therapy. The objective of this study was to investigate the correlation between the results of endoscopic cytology and histopathology. In this study, 167 dogs with clinical signs of chronic gastrointestinal disease were included. On the basis of histopathology, the following diagnoses were determined: lymphocytic-plasmacytic enteritis in 93 dogs; eosinophilic enteritis in 5 dogs; small cell intestinal lymphoma in 45 dogs; and large cell intestinal lymphoma in 24 dogs...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28494702/an-australian-newcastle-disease-virus-with-a-virulent-fusion-protein-cleavage-site-produces-minimal-pathogenicity-in-chickens
#11
Jemma Bergfeld, Joanne Meers, John Bingham, Jennifer Harper, Jean Payne, Sue Lowther, Glenn Marsh, Mary Tachedjian, Deborah Middleton
Newcastle disease is an important disease of poultry caused by virulent strains of Newcastle disease virus (NDV). During the 1998 to 2002 outbreaks of Newcastle disease in Australia, it was observed that the mild clinical signs seen in some chickens infected with NDV did not correlate with the viruses' virulent fusion protein cleavage site motifs or standard pathogenicity indices. The pathogenicity of 2 Australian NDV isolates was evaluated in experimentally challenged chickens based on clinical evaluation, histopathology, immunohistochemistry, and molecular techniques...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28382855/natural-infections-with-pigeon-paramyxovirus-serotype-1-pathologic-changes-in-eurasian-collared-doves-streptopelia-decaocto-and-rock-pigeons-columba-livia-in-the-united-states
#12
M Isidoro-Ayza, C L Afonso, J B Stanton, S Knowles, H S Ip, C L White, H Fenton, M G Ruder, A C Dolinski, J Lankton
Pigeon paramyxovirus serotype 1 (PPMV-1) is a globally distributed, virulent member of the avian paramyxovirus serotype 1 serogroup that causes mortality in columbiformes and poultry. Following introduction into the United States in the mid-1980s, PPMV-1 rapidly spread causing numerous mortality events in Eurasian collared-doves ( Streptopelia decaocto) (ECDOs) and rock pigeons ( Columba livia) (ROPIs). The investigators reviewed pathological findings of 70 naturally infected, free-ranging columbiforms from 25 different mortality events in the United States...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28382854/lymphoma-classification-in-goats
#13
Patti K Kiser, Christiane V Löhr
Lymphoma has been described in individual cases for goats but not systematically characterized in a larger cohort. This study aimed to subtype caprine lymphoma based on topographic and subgross distribution, immunophenotype, and cellular morphology following the World Health Organization classification system for hematopoietic tumors in domestic animals. Fifteen caprine lymphoma cases were assessed with 6 submitted as biopsy and 9 for postmortem examination. Goats were predominantly young adult (median 3 years) and dwarf breeds (Pygmy and Pygora)...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28355108/prognostic-significance-of-canine-mammary-tumor-histologic-subtypes-an-observational-cohort-study-of-229-cases
#14
Roberta Rasotto, Davide Berlato, Michael H Goldschmidt, Valentina Zappulli
Histopathology is considered the gold standard diagnostic method for canine mammary tumors. In 2011, a new histologic classification for canine mammary tumors was proposed. The present study was a 2-year prospective study that validated the 2011 classification as an independent prognostic indicator with multivariate analysis in a population of 229 female dogs, identifying subtype-specific median survival times (MST) and local recurrence/distant metastasis rates. Dogs with benign tumors and carcinoma arising in benign mixed tumors all had an excellent prognosis...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28346126/agreement-between-cytology-and-histopathology-for-regional-lymph-node-metastasis-in-dogs-with-melanocytic-neoplasms
#15
Janet A Grimes, Brad M Matz, Pete W Christopherson, Jey W Koehler, Kelsey K Cappelle, Katelyn C Hlusko, Annette Smith
Melanocytic neoplasms are common in dogs and frequently occur within the oral cavity or in haired skin. The behavior of melanocytic neoplasms is variable and depends on tumor location, size, and histopathologic features. This study compared cytopathology and histopathology of 32 lymph nodes from 27 dogs diagnosed with melanocytic neoplasms. Agreement between the original cytology report, cytology slide review, original histopathology report, and histopathology slide review was determined for each lymph node...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28346124/pax8-napsin-a-and-cd10-as-immunohistochemical-markers-of-canine-renal-cell-carcinoma
#16
Tyler J Peat, Elijah F Edmondson, Margaret A Miller, Dee M DuSold, José A Ramos-Vara
Pax8, napsin A, and CD10 are useful immunohistochemical markers of human renal cell carcinoma (RCC); however, their diagnostic utility in canine RCC is unclear. Forty formalin-fixed paraffin-embedded renal cell carcinomas from dogs (15 papillary, 12 solid, and 13 tubular) and 10 metastases were evaluated for expression of Pax8, napsin A, and CD10. Thirty-nine (98%), 24 (60%), and 19 (50%) tumors expressed Pax8 (nuclear labeling), napsin A (cytoplasmic labeling), and CD10 (cytoplasmic and membranous labeling), respectively...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28346123/panfungal-polymerase-chain-reaction-for-identification-of-fungal-pathogens-in-formalin-fixed-animal-tissues
#17
Courtney Meason-Smith, Erin E Edwards, Caitlin E Older, Mackenzie Branco, Laura K Bryan, Sara D Lawhon, Jan S Suchodolski, Gabriel Gomez, Joanne Mansell, Aline Rodrigues Hoffmann
Identification of fungal organisms often poses a problem for pathologists because the histomorphology of some fungal organisms is not specific, fresh tissues may not be available, and isolation and identification in culture may take a long time. The purpose of this study was to validate the use of panfungal polymerase chain reaction (PCR) to identify fungal organisms from formalin-fixed paraffin-embedded (FFPE) tissues. Formalin-fixed paraffin-embedded curls were tested from 128 blocks containing canine, feline, equine, and bovine tissues with cutaneous, nasal, pulmonary, and systemic fungal infections, identified by the presence of fungi in histologic sections...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28178428/effect-of-histophilus-somni-on-heart-and-brain-microvascular-endothelial-cells
#18
D O'Toole, R Hunter, T Allen, B Zekarias, J Lehmann, K S Kim, D Grab, L B Corbeil
Histophilus somni is a pathogenic gram-negative bacterium responsible for pneumonia and septicemia in cattle. Sequelae include infectious thrombotic meningoencephalitis (ITME), myocarditis, arthritis, and abortion. These syndromes are associated with widespread vasculitis and thrombosis, implicating a role for endothelium in pathogenesis. Histopathologic and immunohistochemical investigation of 10 natural cases of bovine H. somni myocarditis and 1 case of ITME revealed intravascular H. somni in large biofilm-like aggregates adherent to the luminal surface of microvascular endothelium...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28178427/pathogenesis-of-colitis-in-germ-free-mice-infected-with-ehec-o157-h7
#19
K A Eaton, C Fontaine, D I Friedman, N Conti, C J Alteri
Enterohemorrhagic Escherichia coli (EHEC) are strains of E. coli that express Shiga toxins (Stx) and cause hemorrhagic colitis. In some cases, disease can progress to hemolytic uremic syndrome, a potentially fatal form of kidney disease. Both enteric and renal disease are associated with the expression of stx genes, which are often carried on lysogenic phage. Toxin is expressed following induction and conversion of the phage to lytic growth. The authors previously used a germ-free mouse model to demonstrate that toxin gene expression is enhanced during growth in vivo and that renal disease is dependent on both prophage induction and expression of Stx2...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28171733/microsporidiosis-in-four-tortoises-testudo-hermanni-boettgeri
#20
M Eydner, J Donhauser, A Beineke, P Guenther, S Blahak
Microsporidia are obligate intracellular, spore-forming fungi. A wide range of vertebrate and invertebrate hosts can be infected; however, cases of infected turtles or tortoises have not yet been described. This is the first description of 4 cases in tortoises ( Testudo spp), which showed general signs of illness as well as intestinal and respiratory signs until death occurred or they were euthanized. Granulomatous and necrotizing inflammation was visible in the lung and liver. Fungal organisms were present in heart blood, lung, liver, and intestine...
July 2017: Veterinary Pathology
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