journal
MENU ▼
Read by QxMD icon Read
search

International Journal of Neuroscience

journal
https://www.readbyqxmd.com/read/28332424/neuroprotective-effect-of-dl-3-n-butylphthalide-on-patients-with-radiation-induced-brain-injury-a-clinical-retrospective-cohort-study
#1
Xiaoni Zhang, Yi Li, Xiangpen Li, Xiaoming Rong, Yamei Tang, Ying Peng
PURPOSE: To evaluate the neuroprotective effects of Dl-3-n-butylphthalide (NBP) on patients with radiation-induced brain injury, a hospital-based, clinical retrospective cohort study was conducted. PATIENTS AND METHODS: Data was collected on patients diagnosed with radiation-induced brain injury from January 2009 to January 2015 in Department of Neurology, Sun Yat-Sen Memorial Hospital. All patients enrolled have received cranial radiotherapy and were diagnosed with radiation-induced brain injury...
March 23, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28316267/efficacy-of-a-computer-based-cognitive-training-program-in-older-people-with-subjective-memory-complaints-a-randomized-study
#2
Angela J Pereira-Morales, Andrés F Cruz Salinas, Jairo Aponte Melo, Francisco Pereira Manrique
OBJECTIVE: the aim of this study was to investigate the effect of computer-assisted cognitive training in healthy older adults with subjective memory complaints. METHODS: 40 older adults, mean age (standard Deviation) = 66.4 (5.6) with subjective memory complaints, were included in this study. Participants were randomly assigned to an Integrated Psychostimulation Program (IPP) (N = 17), a Computerized Cognitive Training (CCT) (N = 12) or a control group (N = 11)...
March 20, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28288541/risk-of-subsequent-cancer-among-pediatric-adult-and-elderly-patients-following-a-primary-diagnosis-of-glioblastoma-multiforme-a-population-based-study-of-the-seer-database
#3
Xuezhen Li, Yanbin Li, Yang Cao, Li Peiliang, Bo Liang, Jidian Sun, Enshan Feng
Purpose/aim of the study: Our objective was to determine the risk of a subsequent malignancy in patients with glioblastoma multiforme (GBM). MATERIALS AND METHODS: Data of patients with a primary diagnosis of GBM were extracted from the Surveillance, Epidemiology, and End Results database. Patients were divided into 3 age groups: pediatric, ≤ 19 years of age; adult, 20-59 years; elderly, ≥ 60 years. Outcomes were overall survival and incidence of second cancer. RESULTS: A total of 24,348 patients with primary GBM were identified during the period from 2004-2013; 349 pediatric, 9,841 adults, and 14,518 elderly...
March 14, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28281852/the-patterns-of-eeg-changes-in-early-onset-parkinson-s-disease-patients
#4
Xuetao He, Yuhu Zhang, Jieling Chen, Chunge Xie, Rong Gan, Rong Yang, Limin Wang, Kun Nie, Lijuan Wang
The aim of this study was to investigate the patterns of brain activities changes in early-onset parkinson's disease(EOPD) patients and its relationship with the severity of disease and motor deterioration. Electroencephalography (EEG) was performed in a sample of 52 nondemented EOPD patients and 20 healthy controls with similar age. All patients underwent a battery to assess PD severity and motor deterioration. The EEG data were rated by visual and quantitative analyses with the Grant total EEG(GTE) score and NicoletOne Software...
March 10, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28270030/mean-platelet-volume-platelet-count-ratio-as-a-predictor-of-90-day-outcome-in-large-artery-atherosclerosis-stroke-patients
#5
Weiwei Quan, Zhibo Chen, Xuezhi Yang, Jia Li, Xiang Li, Yiyun Weng, Youyu Li, Xu Zhang
OBJECTIVE: Previous studies reported a lower platelet count (PC) level and a higher mean platelet volume (MPV) level in severe ischemic stroke. We define MPV/PC as the platelet ratio (PR). This study investigates the relationship between PR and 90-day outcome of large artery atherosclerosis (LAA) stroke. MATERIALS AND METHODS: A retrospective analysis was conducted on 338 LAA patients in two hospitals by looking up the electronic medical record (EMR). The 90-day functional outcome was divided into good and poor according to the modified Rankin Scale (mRS) score...
March 7, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28110588/neuroprotective-effects-of-adjunctive-treatments-for-acute-stroke-thrombolysis-a-review-of-clinical-evidence
#6
Hongxing Zhou, Suyun Huang, Gavin Sunnassee, Weiyu Guo, Jian Chen, Yang Guo, Sheng Tan
The narrow therapeutic time window and risk of intracranial hemorrhage largely restrict the clinical application of thrombolysis in acute ischemic stroke. Adjunctive treatments added to rt-PA may be beneficial to improve the capacity of neural cell to withstand ischemia, and to reduce the hemorrhage risk as well. This review aims to evaluate the neuroprotective effects of adjunctive treatments in combination with thrombolytic therapy for acute ischemic stroke. Relevant studies were searched in the PubMed, Web of Science and EMBASE database...
February 7, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28102719/pregnancy-and-delivery-in-women-with-spinal-muscular-atrophy
#7
Bakri H Elsheikh, Xiaoli Zhang, Kathryn J Swoboda, Sharon Chelnick, Sandra P Reyna, Stephen J Kolb, John T Kissel
OBJECTIVES: To expand the limited available knowledge about pregnancy and delivery in women with spinal muscular atrophy (SMA) using a cohort of genetically proven SMA patients from USA. METHODS: This was a cross-sectional questionnaire-based study. We mailed questionnaires to 58 women with confirmed SMA. RESULTS: Thirty-two women responded, reporting 35 pregnancies, including 19 women with at least one pregnancy. In this cohort, preterm labor and delivery by cesarean section were more common in mothers with SMA particularly SMA type 2...
February 5, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28100092/sample-size-requirements-for-one-year-treatment-effects-using-deep-gray-matter-volume-from-3t-mri-in-progressive-forms-of-multiple-sclerosis
#8
Gloria Kim, Renxin Chu, Fawad Yousuf, Shahamat Tauhid, Lynn Stazzone, Maria K Houtchens, James M Stankiewicz, Christopher Severson, Dorlan Kimbrough, Francisco J Quintana, Tanuja Chitnis, Howard L Weiner, Brian C Healy, Rohit Bakshi
OBJECTIVE: The subcortical deep gray matter (DGM) develops selective, progressive, and clinically relevant atrophy in progressive forms of multiple sclerosis (PMS). This patient population is the target of active neurotherapeutic development, requiring the availability of outcome measures. We tested a fully automated MRI analysis pipeline to assess DGM atrophy in PMS. DESIGN/METHODS: Consistent 3D T1-weighted high-resolution 3T brain MRI was obtained over one year in 19 consecutive patients with PMS [15 secondary progressive, 4 primary progressive, 53% women, age (mean±SD) 50...
February 2, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28052710/depression-after-stroke-at-12-month-follow-up-a-multicenter-study
#9
Patchara Limampai, Wanpen Wongsrithep, Vilai Kuptniratsaikul
PURPOSE: To study the prevalence of depression at 12 months after stroke and to analyze factors associated with depression. METHODS: This prospective cross-sectional study was conducted among nine tertiary hospitals in Thailand. Stroke patients from the Thai Stroke Rehabilitation Registry who were admitted in inpatient rehabilitation wards were recruited for evaluation at the 12-month follow-up time point. Hospital Anxiety and Depression Scale (HADS) was used to evaluate depression in stroke...
February 2, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28042930/three-versus-seven-days-to-return-to-work-after-mild-traumatic-brain-injury-a-randomized-parallel-group-trial-with-neuropsychological-assessment
#10
Aline M Studerus-Germann, Doortje C Engel, Martin N Stienen, Dieter von Ow, Gerhard Hildebrandt, Oliver P Gautschi
Although most patients with a mild traumatic brain injury (mTBI) recover within days to weeks, some experience persistent physical, cognitive and emotional symptoms, often described as post-concussion syndrome (PCS). The optimal recovery time including return-to-work (RTW) after mTBI is unclear. In this single-centre parallel-group trial, patients assigned three days (3D-group) or seven days (7D-group) sick leave were compared with a comprehensive neuropsychological test battery including the Post-Concussion Symptom Scale (PCSS) within one week, after three and 12 months post-injury...
February 2, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28140735/risk-factors-affecting-prognosis-in-infantile-spasm
#11
Gulen Gul Mert, Ozlem Herguner, Faruk Incecik, Sakir Altunbasak, Duygu Sahan, Ilker Unal
AIM: To assess risk factors that affect epilepsy prognosis and neurodevelopmental outcome and response to treatment in patients diagnosed with infantile spasm. METHODS: In this study, demographics, treatment modalities, etiologies, risk factors affecting neurodevelopmental outcome and epilepsy prognosis were assessed retrospectively at the end of a minimum 24-months follow-up of 104 patients diagnosed with infantile spasm from May 2012 to October 2015. RESULTS: Neonatal seizure during neonatal period, abnormal head circumference, young age at the time of presentation and early gestational age, symptomatic etiology, abnormal initial examination and abnormal development test at the time of diagnosis, consanguinity, the medical center where treatment was started in the second center or beyond and magnetic resonance imaging finding were found to be statistically significant for poor prognosis in terms of neurodevelopment (p <0...
January 31, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28092225/comparison-of-dysphagia-outcomes-between-rostral-and-caudal-lateral-medullary-infarct-patients
#12
Min Ho Chun, Daeha Kim, Min Cheol Chang
OBJECTIVE: A detailed knowledge of dysphagia outcomes in lateral medullary infarct (LMI) patients would enable proper establishment of swallowing therapy goals and strategies. However, little is known about the impact of infarct location on dysphagia outcomes in patients with LMI. METHODS: Twenty patients with rostral LMI (rostral group) and 20 patients with caudal LMI (caudal group) participated in the study. All patients underwent swallowing therapy, which included compensatory treatments and strengthening exercises, for >3 months...
January 31, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28132574/robotic-assisted-gait-training-in-parkinson-s-disease-a-3-month-follow-up-randomized-clinical-trial
#13
Anna Furnari, Rocco Salvatore Calabrò, Maria Cristina De Cola, Marcello Bartolo, Alberto Castelli, Alessia Mapelli, Giampiero Buttacchio, Elena Farini, Placido Bramanti, Roberto Casale
PURPOSE: The aim of this study was to evaluate the efficacy of a Robotic-Assisted Gait Training (RAGT), together with a conventional exercise program (CEP), to improve PD ambulation, as compared to standard gait training. METHODS: Thirty-eight patients with mild PD stage (H&Y 2-2.5) were randomly assigned to an experimental group (EG) or a control group (CG). The 19 patients in EG received 30 min RAGT (using Lokomat device), whereas the 19 controls received a conventional gait training; both groups received 30 min of CEP...
January 28, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28074658/hyperglycemia-as-a-prognosis-predictor-of-length-of-stay-and-functional-outcomes-in-patients-with-acute-ischemic-stroke
#14
Abdul Gofir, Budi Mulyono, Sri Sutarni
BACKGROUND: Hyperglycemia has been shown to influence prognosis outcome of stroke. The objective of this study was to determine the correlation between hyperglycemia with length of stay (LOS) and functional outcomes in ischemic stroke patients. This is the first study to correlate hyperglycemia in ischemic stroke patients with their functional outcome as assessed by using Barthel index. METHODS: This is a prospective cohort study of patients admitted to the Stroke Unit of Dr...
January 27, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/27838939/aquaporin-4-antibody-in-neuromyelitis-optica-re-testing-study-in-a-large-population-from-china
#15
Youming Long, Junyan Liang, Rong Zhong, Linzhan Wu, Wei Qiu, Shaopeng Lin, Cong Gao, Xiaohui Chen, Xueping Zheng, Ning Yang, Min Gao, Zhanhang Wang
BACKGROUND: Aquaporin-4 (AQP4) antibody sero-positivity is critically important in neuromyelitis optica (NMO). However, the sensitivity of different assays is highly variable. Repeating detection with a highly sensitive assay in a large population is necessary in the case of so-called negative NMO. METHODS: Retrospective analysis where AQP4 antibodies were detected by commercial cell-based assay (CBA), in-house M23-CBA and in-house M1-CBA. RESULTS: Of the 1011 serum samples, 206 (20...
January 27, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28125929/trans-synaptic-degeneration-of-motoneurons-distal-to-chronic-cervical-spinal-cord-compression-in-cervical-spondylotic-myelopathy
#16
Chaojun Zheng, Yu Zhu, Feizhou Lu, Xiaosheng Ma, Dong Tian, Jianyuan Jiang
OBJECTIVE: To assess the effect of chronic cervical spinal cord compression upon remote motor unit function in patients with cervical spondylotic myelopathy (CSM). METHODS: Fifty-three CSM patients and 47 healthy subjects were included. Bilateral motor unit number estimations (MUNEs) were recorded from both abductor digiti minimi and abductor pollicis brevis, and bilateral flexor carpi radialis (FCR) H-reflexes were examined in all subjects along with the nine-hole peg test (NHPT)...
January 26, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28076692/the-effects-of-ultrasound-guided-corticosteroid-injection-for-the-treatment-of-hemiplegic-shoulder-pain-on-depression-and-anxiety-in-patients-with-chronic-stroke
#17
Min Cheol Chang
PURPOSE: We attempted to investigate whether ultrasound (US)-guided intra-articular or subacromial bursa corticosteroid injections can potentially influence the severity of depression and anxiety in patients with chronic stroke with hemiplegic shoulder pain (HSP). METHODS: Thirty patients with chronic stroke with HSP received US-guided corticosteroid injections. Numeric rating scale (NRS) scores, passive shoulder range of motion (ROM), Beck Depression Inventory (BDI) scores and Spielberger State-Trait Anxiety Inventory (STAI) scores were evaluated before the injection, and one and two months after the injection...
January 25, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28117613/relation-between-serum%C3%A2-leptin%C3%A2-levels-lipid-profiles-%C3%A2-and-neurocognitive-deficits-in-chinese-osahs-patients
#18
Yating Peng, Li Zhou, Yuping Cao, Ping Chen, Yan Chen, Dandan Zong, Ruoyun Ouyang
Objective The aim of this study was to compare serum leptin, apolipoprotein A1 (ApoA1), apolipoprotein J (ApoJ), and apolipoprotein H (ApoH) levels in males with obstructive sleep apnea and hypopnea syndrome (OSAHS) to those in healthy control subjects and to examine the possible relation between neurocognitive performance and these factors/serum markers in the subjects. Methods In this observational, cross-sectional study, a full-night polysomnography and sensitive neuropsychological assessment were performed on 50 newly diagnosed Chinese male patients and 30 healthy subjects...
January 24, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28110595/protein-aggregation-misfolding-and-consequential-human-neurodegenerative-diseases
#19
Neha Sami, Safikur Rahman, Vijay Kumar, Sobia Zaidi, Asimul Islam, Sher Ali, Faizan Ahmad, Md Imtaiyaz Hassan
Proteins are major components of the biological functions in a cell. Biology demands that a protein must fold into its stable three-dimensional structure to become functional. In an unfavorable cellular environment, protein may get misfolded resulting in its aggregation. These conformational disorders are directly related to the tissue damage resulting in cellular dysfunction giving rise to different diseases. This way, several neurodegenerative diseases such as Alzheimer, Parkinson, Huntington diseases and amyotrophic lateral sclerosis are caused...
January 23, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28051884/the-risk-factors-and-pattern-of-cerebral-microbleeds-in-parkinson-s-disease
#20
Dian He, Chun-Feng Liu, Lan Chu, Ya Li, Da-Fei Xu, Ling Jiao
BACKGROUND AND PURPOSE: Cerebral microbleeds (CMBs) in Parkinson's disease (PD) have been reported recently and concerned increasingly. Our aim was to investigate the risk factors and pattern of CMBs in patients with PD, as well as the influence of risk factors on the pattern of CMBs. METHODS: We retrospectively collected medical and imaging data of 247 patients who underwent brain susceptibility-weighted imaging. Logistic regression analyses were performed to determine the risk factors of CMBs...
January 17, 2017: International Journal of Neuroscience
journal
journal
22686
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"