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International Urology and Nephrology

Raouf Seyam, Mahmoud I Khalil, Mohamed H Kamel, Waleed M Altaweel, Rodney Davis, Nabil K Bissada
PURPOSE: Organ-sparing surgery (OSS) for the kidney and adrenals has emerged as the need for preservation of function is paramount in patients with poor functional reserve. As reports increasingly showed that oncological outcomes were equivalent to radical excision, elective OSS became a viable alternative in patients with otherwise normal reserve. In this review, we summarize the current knowledge of OSS for adrenal and renal tumors. MATERIALS AND METHODS: PubMed, Web of Science and Cochrane Library Central Search were searched for recently published articles up to December 2017...
January 8, 2019: International Urology and Nephrology
Tomasz W Kaminski, Krystyna Pawlak, Malgorzata Karbowska, Beata Znorko, Adrian L Mor, Michal Mysliwiec, Dariusz Pawlak
PURPOSE: Indoxyl sulfate (IS) is one of the most potent uremic toxins involved in chronic kidney disease (CKD) progression, induction of inflammation, oxidative stress, and cardiovascular diseases occurrence. It is proved that hypertension is a common CVD complication and a major death risk factor as well as contributes for decline in a renal function. The aim of our study was to investigate how implementing of antihypertensive therapy impact IS concentrations and the associations between IS and markers of renal function, inflammation and oxidative stress...
January 7, 2019: International Urology and Nephrology
Pankaj N Maheshwari, Ashish Chaurasia, Nick Okwi, Nassaka Victo Mukasa
No abstract text is available yet for this article.
January 7, 2019: International Urology and Nephrology
Tao Wang, Yan Zhang, MaoDong Liu, Xi Kang, Lin Kang, Hui Zhang
No abstract text is available yet for this article.
January 3, 2019: International Urology and Nephrology
Min Yang, Letao Lin, Guochen Niu, Ziguang Yan, Bihui Zhang, Xiaoqiang Tong, Yinghua Zou
PURPOSE: To evaluate in a retrospective, single-center, case series if percutaneous transluminal renal angioplasty/stenting of chronic renal artery occlusion is beneficial to renal function and blood pressure control, which remains controversial. METHODS: Data from 15 consecutive patients with renal artery stump who underwent successful percutaneous transluminal renal angioplasty/stenting only for unilateral chronic renal artery occlusion at our center from January 2007 to February 2018 and completed follow-up were retrospectively evaluated...
January 3, 2019: International Urology and Nephrology
Ryuichi Kawamoto, Daisuke Ninomiya, Asuka Kikuchi, Taichi Akase, Yoshihisa Kasai, Tomo Kusunoki, Nobuyuki Ohtsuka, Teru Kumagi
PURPOSE: Neutrophil-to-lymphocyte ratio (NLR) was widely studied as a prognostic marker in various medical and surgical specialties, but its significance in diabetic kidney disease is not yet established. METHODS: The subjects comprised 199 men aged 73 ± 11 (mean ± standard deviation) years and 187 women aged 77 ± 10 years from a rural hospital. We examined the relationship between NLR calculated by analyzing differential leukocyte count in complete blood picture and renal function evaluated by estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease Study Group equation and urinary albumin excretion (UAE)...
January 3, 2019: International Urology and Nephrology
Osamu Ichiyanagi, Hiroki Fukuhara, Masayuki Kurokawa, Takuji Izumi, Hitoshi Suzuki, Sei Naito, Hayato Nishida, Tomoyuki Kato, Norihiko Tsuchiya
PURPOSE: We investigated the clinical efficacy of the Triple D score (TrD-S) on stone-free rate (SFR) prediction following shockwave lithotripsy (SWL) for renal stones 10-20 mm in diameter and modified the scoring system to improve outcome prediction. METHODS: We retrospectively examined clinical data from the medical records of 226 consecutive patients who underwent SWL for 10-20 mm kidney stones. The TrD-S was calculated according to the cutoffs of < 150 mm3 for stone volume, < 600 Hounsfield unit for stone density, and < 12 cm for skin-to-stone distance on computed tomography...
January 2, 2019: International Urology and Nephrology
Fikriye Yasemin Ozatik, Yasemin Teksen, Emine Kadioglu, Orhan Ozatik, Zeynep Bayat
INTRODUCTION AND AIM: Hydrogen sulfide (H2 S) is an endogenously produced gas-structure mediator. It is proposed to have antioxidant, anti-inflammatory and antiapoptotic effects. Acetaminophen (N-acetyl-P-aminophenol; APAP) is an antipyretic and analgesic medication known as paracetamol. When taken at therapeutic doses there are few side-effects, but at high doses APAP can cause clear liver and kidney damage in humans and experimental animals. In this study, the effects of the H2 S donor of sodium hydrosulfide (NaHS) on acute renal toxicity induced by APAP in rats were researched in comparison with N-acetyl cysteine (NAC)...
January 2, 2019: International Urology and Nephrology
John J Sim, Hui Zhou, Jiaxiao Shi, Sally F Shaw, Shayna L Henry, Csaba P Kovesdy, Kamyar Kalantar-Zadeh, Steven J Jacobsen
In the original publication, age stratified mortality rates were incorrectly added in Fig. 2. The correct Fig. 2 is given below.
January 2, 2019: International Urology and Nephrology
Laurens Veldeman, Jill Vanmassenhove, Wim Van Biesen, Ziad A Massy, Sophie Liabeuf, Griet Glorieux, Raymond Vanholder
BACKGROUND: There is a gradual increase in serum concentrations of protein-bound colon-derived uremic toxins indoxyl sulphate (IxS) and p-cresyl sulphate (pCS) as chronic kidney disease (CKD) progresses. In acute kidney injury (AKI), up till now, the retention pattern has not been studied. METHODS: In this study, 194 adult patients admitted with sepsis to the intensive care unit were included. IxS, pCS and serum creatinine (sCrea) were quantified at inclusion (D0) and at day 4, unless follow-up ended earlier (Dend )...
January 2, 2019: International Urology and Nephrology
Tuncay Kiris, Eyup Avci, Aykan Celik
AIM: We investigated the predictive value of the blood urea nitrogen-to-left ventricular ejection fraction ratio (BUNEFr) to evaluate the risk of contrast-induced nephropathy (CIN) in acute coronary syndrome (ACS) patients who were treated with percutaneous coronary intervention (PCI). METHODS: A total of 1010 ACS patients undergoing PCI were included in this study. The serum creatinine level was measured before and within 48-72 h of contrast medium administration...
January 2, 2019: International Urology and Nephrology
Monika Lichodziejewska-Niemierko, Michał Chmielewski, Ewa Wojtaszek, Ewa Suchowierska, Edyta Gołembiewska, Magdalena Grajewska, Joanna Matuszkiewicz-Rowińska, Beata Naumnik, Beata Sulikowska, Stanisław Niemczyk, Renata Kłak, Magdalena Mosakowska, Piotr Jagodziński, Bernadeta Marcykiewicz, Krzysztof Kalita, Robert Krawczyk, Krzysztof Cieszyński, Mirosław Adamski, Marek Bronk
BACKGROUND: Peritoneal dialysis (PD) related infections are associated with technique failure and mortality. The aim of this multicentre study was to examine epidemiology, treatment and outcomes of PD-related infections in Poland as well as practice patterns for prevention of these complications in the context of current ISPD recommendations. METHODS: A survey on PD practices in relation to infectious complications was conducted in 11 large Polish PD centres. Epidemiology of peritonitis and exit-site infections (ESI) was examined in all patients treated in these units over a 2 year period...
January 2, 2019: International Urology and Nephrology
Jang-Wook Lee, Kwang-Hoon Lee
PURPOSE: This study aimed to compare the renoprotective effect between febuxostat and allopurinol in hyperuricemic patients with chronic kidney disease (CKD), about which limited data are available. METHODS: 141 patients with stage 3 CKD and hyperuricemia were followed from June 2005 to April 2018. Thirty patients received febuxostat, 40 allopurinol and 71 conventional CKD management only (control group). We compared the mean serum uric acid levels, estimated glomerular filtration rate (eGFR) changes over time and renal survival time free from predefined renal disease progression among these 3 groups...
January 2, 2019: International Urology and Nephrology
Kun Ling Ma, Liang Liu, Yang Zhang, Gui Hua Wang, Ze Bo Hu, Pei Pei Chen, Jian Lu, Chen Chen Lu, Tie Kai Gong, Yu Xiang Gong, Bi Cheng Liu
AIM: This study aimed to investigate the effects of aspirin on podocyte injury and its underlying mechanisms in diabetic nephropathy (DN). METHODS: Eight-week-old male Sprague-Dawley rats were divided into three groups: non-diabetic rats (Control), streptozotocin-induced diabetic rats (DM), and diabetic rats treated with aspirin (DM + Aspirin) for 12 weeks. Intracellular lipid accumulation was evaluated by Oil Red O staining and quantitative free cholesterol assays...
January 2, 2019: International Urology and Nephrology
Marco Ostuni, Carlos G Musso
There is interdependence between chronic kidney disease (CKD) and ageing whereby CKD makes ageing more accelerated and pronounced, whereas ageing accelerates chronic nephropathy's progression. Frailty status catalyzes this spiral, with renal and systemic negative consequences, and this condition can currently be documented by applying already validated clinical scores (frailty phenotype) or physical test (gate speed). Although, nephroprevention strategies are similar between young adult and senior CKD patients, standard targets should be adequate to very old and frail elderly individuals...
January 2, 2019: International Urology and Nephrology
M C Sighinolfi, M Sandri, A Eissa, A El Sherbiny, S Micali, G Bianchi, B Rocco
No abstract text is available yet for this article.
January 2, 2019: International Urology and Nephrology
D A El Sewefy, B A Farweez, M A Behairy, N R Yassin
PURPOSE: Anaemia and resistance to erythropoiesis-stimulating agents (ESAs) are common complications in haemodialysis (HD) patients. We investigated the role of hepcidin in the development of anaemia and ESA resistance/hyporesponsiveness and its relation to the plasma levels of the inflammatory markers interleukin 6 (IL-6) and high-sensitivity C-reactive protein (hsCRP). METHODS: This study included 60 maintenance HD patients attending Ain Shams University Hospital and 30 age- and sex-matched healthy subjects as a control group...
January 2, 2019: International Urology and Nephrology
Barbara Pietrzyk, Katarzyna Wyskida, Joanna Ficek, Aureliusz Kolonko, Rafał Ficek, Andrzej Więcek, Magdalena Olszanecka-Glinianowicz, Jerzy Chudek
PURPOSE: Data concerning the relation between increased levels of circulating sclerostin (a physiological inhibitor of bone formation) and bone turnover in patients with chronic renal failure (CRF) are limited. Therefore, the aim of this study was to evaluate associations between plasma sclerostin levels and calcium-phosphate disturbances, markers of bone turnover as well as inflammation in haemodialysis (HD) patients. METHODS: In plasma samples obtained in 150 stable HD patients (92 men) aged 40-70 years, levels of sclerostin, fibroblast growth factor (cFGF23), osteocalcin, the N-terminal propeptide of type I procollagen, C-terminal telopeptide of the alpha chain of type I collagen (β-CTx), and inflammatory markers (IL-6 and TNF-α) in addition to routine parameters (calcium, phosphorus, parathyroid hormone-iPTH, 25-OH-D, alkaline phosphatase) were measured...
December 24, 2018: International Urology and Nephrology
Attia Abd Allah Attia, Mohamed Abd El Mawgood Amer, Mamdouh Hassan, Sameh Fayek GamalEl Din
PURPOSE: The purpose of the study was to compare serum level of folic acid (FA) in patients with erectile dysfunction (ED) versus healthy controls and to assess its correlation with other well-known confounders for ED. METHODS: Our prospective study compared FA in 60 patients with ED versus 30 healthy controls. Patients were excluded if they had any hormonal disorders, Peyronie's disease, or decompensated systemic illnesses. ED was evaluated by the validated Arabic version of the abbreviated five-item form of the International Index Of Erectile Function and confirmed by penile duplex...
December 13, 2018: International Urology and Nephrology
Smail Acimi, Mimouna Bessahraoui, Mohammed Ali Acimi, Naima Abderrahmane, Lamia Debbous
PURPOSE: To report current results of vaginoplasty using the mucosa of the prepuce, and creating labia minora by penile skin in children with disorders of sex development (DSD). METHODS: In 10 years, we have performed 22 vaginoplasties using the described technique of vaginoplasty, 21 patients with 46, XX DSD and 1 ovotesticular DSD. The assessment of the results of this technique of vaginoplasty was undertaken in several stages: (a) The evaluation of the cosmetic result...
December 13, 2018: International Urology and Nephrology
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