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International Urology and Nephrology

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https://www.readbyqxmd.com/read/28825202/serum-%C3%AE-glutamyltransferase-and-subsequent-chronic-kidney-disease-in-a-prospective-study
#1
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
August 19, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28815356/dent-disease-in-poland-what-we-have-learned-so-far
#2
Marcin Zaniew, Małgorzata Mizerska-Wasiak, Iga Załuska-Leśniewska, Piotr Adamczyk, Katarzyna Kiliś-Pstrusińska, Adam Haliński, Jan Zawadzki, Beata S Lipska-Ziętkiewicz, Krzysztof Pawlaczyk, Przemysław Sikora, Michael Ludwig, Maria Szczepańska
PURPOSE: Dent disease (DD) is a rare tubulopathy characterized by proximal tubular dysfunction leading to chronic kidney disease (CKD). The aim of the study was to characterize patients with DD in Poland. METHODS: A retrospective analysis of a national cohort with genetically confirmed diagnosis. RESULTS: Of 24 males, all patients except one carried mutations in the CLCN5 gene; in one patient a mutation in the OCRL gene was disclosed. Molecular diagnosis was delayed 1 year on average (range 0-21 years)...
August 16, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28808864/elevated-bilirubin-levels-and-risk-of-developing-chronic-kidney-disease-a-dose-response-meta-analysis-and-systematic-review-of-cohort-studies
#3
REVIEW
Jun Wang, Peng Guo, ZhengYan Gao, BenGang Zhou, Lei Ren, Yu Chen, Quan Zhou
AIMS: Previous studies have indicated the link of bilirubin levels and risk of developing chronic kidney disease (CKD); however, the findings were inconsistent. METHODS: We searched for cohort studies examining bilirubin as an exposure and CKD as an outcome in the Medline, EMBASE, and Web of Science databases from inception through November 31, 2016. A generalized least-squares approach was applied to assess the dose-response relationship between them by pooling rate ratios with 95% confidence intervals...
August 14, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28808847/evaluation-of-hyoscine-n-butyl-bromide-efficacy-on-the-prevention-of-catheter-related-bladder-discomfort-after-transurethral-resection-of-prostate-a-randomized-double-blind-control-trial
#4
Golnar Sabetian, Farid Zand, Elham Asadpour, Mohammad Ghorbani, Pourya Adibi, Mohammad Mehdi Hosseini, Shahryar Zeyghami, Farzaneh Masihi
BACKGROUND: Transurethral resection of prostate (TURP) is the most common treatment for benign prostatic hyperplasia (BPH). Urinary tract catheter is inserted post-operatively which results in catheter-related bladder discomfort (CRBD) in many patients. The purpose of this study was to assess the preventive effect of hyoscine N-butyl bromide on CRBD caused by a urinary tract catheter after TURP surgery in patients with BPH. METHODS: Twenty-four and twenty-six patients in the treatment and control groups were enrolled, respectively...
August 14, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28803386/sexual-intercourse-as-a-new-option-in-the-medical-expulsive-therapy-of-distal-ureteral-stones-in-males-a-prospective-randomized-controlled-study
#5
Zeki Bayraktar, Selami Albayrak
PURPOSE: To investigate the effect of sexual intercourse on the spontaneous passage of distal ureteral stones 5-10 mm in size. METHODS: A total of 190 male patients with distal ureteral stones were randomly divided into three groups. Patients in group 1 were administered tamsulosin 0.4 mg/day (n = 60). Patients in group 2 were asked to have sexual intercourse at least three times a week (n = 66). Patients in group 3 received standard medical therapy alone and acted as the controls (n = 64)...
August 12, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28799121/3-t-multiparametric-mri-characteristics-of-prostate-cancer-patients-suspicious-for-biochemical-recurrence-after-primary-focal-cryosurgery-hemiablation
#6
Michael Kongnyuy, Daniel M Halpern, Corinne C Liu, Kaitlin E Kosinski, David J Habibian, Anthony T Corcoran, Aaron E Katz
INTRODUCTION: We aimed to report on multiparametric MRI (mpMRI) characteristics of post-primary focal cryosurgery (PFC) patients suspected of biochemical recurrence (BCR) by the Phoenix criteria. METHODS: We retrospectively reviewed all patients at our institution who had undergone PFC. Prostate-specific antigen nadir was determined using 2 or more post-PFC values. Suspicion of BCR was determined using the Phoenix criteria (nadir + 2 ng/ml). At the discretion of the physician, pre-and post-PFC 3-T mpMRIs were obtained and in a few cases biopsies were performed...
August 10, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28795269/an-initial-differential-renal-function-between-35-and-40-has-greater-probability-of-leading-to-normal-after-pyeloplasty-in-patients-with-unilateral-pelvic-ureteric-junction-obstruction
#7
Guofeng Xu, Maosheng Xu, Jianqi Ma, Zhoutong Chen, Dapeng Jiang, Zhihua Hong, Houwei Lin, Xiaoliang Fang, Liguo Wang, Lei He, Hongquan Geng
PURPOSE: We compared the outcomes in patients who were <1 year old and had hydronephrosis with SFU grade 3-4 PUJ obstruction to observe the potential recovery of renal morphology and DRF after successful pyeloplasty. METHODS: All children younger than 1 year old with SFU grade 3-4 PUJ obstruction from January 2013 to June 2015 were retrospectively analyzed. A total of 92 children were grouped according to their DRF value at pyeloplasty as follows: DRF from 30 to ≤35% (group I) and DRF from 35 to ≤40% (group II)...
August 9, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28780626/prospective-controlled-assessment-of-men-s-sexual-function-changes-following-holmium-laser-enucleation-of-the-prostate-for-treatment-of-benign-prostate-hyperplasia
#8
Ahmed M Elshal, Ahmed El-Assmy, Ramy Mekkawy, Diaa-Eldin Taha, Ahmed R El-Nahas, Mahmoud Laymon, Hamdy El-Kappany, El-Housseiny Ibrahiem
OBJECTIVES: To assess how much Holmium laser enucleation of the prostate (HoLEP) is detrimental on men sexuality. METHODS: Between January and December 2013, all patients presented for BPH surgery were assessed using IIEF-15 (international index of erectile function-15) and Ej-MSHQ (ejaculatory domain-male sexual health questionnaire). Changes in men's sexuality following HoLEP in relation to control procedure were prospectively assessed. Intervention group included legible consecutive patients treated by HoLEP...
August 5, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28776219/tubular-secretion-in-chronic-kidney-disease-staging-a-new-proposal
#9
LETTER
Carlos G Musso, Cristina Gavrilovici, Adrian Covic
No abstract text is available yet for this article.
August 3, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28770419/urinary-biomarkers-in-patients-with-detrusor-underactivity-with-and-without-bladder-function-recovery
#10
Sheng-Fu Chen, Yuan-Hong Jiang, Hann-Chorng Kuo
PURPOSE: Detrusor underactivity (DU) is frequently encountered in elderly patients. Part of patients with DU might have bladder function recovery after treatment. This study investigated urinary proteins in these DU patients with and without bladder function recovery. METHODS: A total of 37 patients with chronic urinary retention and urodynamically proven DU were enrolled. After treatment, 24 DU patients had bladder function recovery whereas 13 had not, after 1-year follow-up...
August 2, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28762118/laparoscopic-and-robotic-nephroureterectomy-does-lymphadenectomy-have-an-impact-on-the-clinical-outcome
#11
Nessn H Azawi, Kasper Drimer Berg, Andreas Key Milan Thamsborg, Claus Dahl, Jan Viberg Jepsen, Bjarne Kroman-Andersen, Johan Poulsen, Helle Handler Petersen, L Henning Olsen, Jørgen Bjerggaard Jensen
PURPOSE: To evaluate the effect of lymphadenectomy (LND) in conjunction with nephroureterectomy on cancer-specific mortality (CSM) and overall survival (OS) for patients with muscle-invasive UTUC. METHODS: A retrospective, multicenter study of patients with UTUC, clinical stage N0M0, who underwent nephroureterectomy between January 2008 and December 2014 was conducted. Outcome measures were OS and CSM. RESULTS: In total, 298 patients underwent robot-assisted or laparoscopic radical nephroureterectomy with a final histological diagnosis of UTUC...
July 31, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28762117/long-term-costs-and-survival-of-prostate-cancer-a-population-based-study
#12
Valentin Brodszky, Péter Varga, Judit Gimesi-Országh, Petra Fadgyas-Freyler, Imre Boncz, Péter Nyirády, Péter Riesz, Petra Baji, Márta Péntek, Fanni Rencz, László Gulácsi
PURPOSE: There is a rising interest in measuring the societal burden of malignancies including prostate cancer. However, population-based studies reporting incidence costs of prostate cancer in the long term are lacking in Europe. The objectives of the study are to analyse the long-term costs and survival of prostate cancer patients treated by radical prostatectomy (RP) or conservative management (nRP). METHODS: A retrospective claims data analysis of the National Health Insurance Found Administration of Hungary between 01...
July 31, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28756611/expression-of-%C3%AE-adrenergic-receptor-subtypes-in-human-normal-and-dilated-ureter
#13
Hailin Shen, Zhipeng Chen, Al-Dhabi Mokhtar, Xiaojun Bi, Guolin Wu, Shide Gong, Chuanyang Huang, Shuai Li, Shuqi Du
BACKGROUND: Ureter peristalsis is a basic physiological function regulated by myogenic and neurogenic factors. The distribution and function of β-adrenergic receptors (β-AR) in the human ureter remain unknown. The aim of this study was to investigate the expression of β-AR subtypes in the normal and dilated human ureter. METHODS: The upper, middle, and lower segments of normal and dilated ureters were collected from patients undergoing surgery for carcinoma of the kidney and upper urinary tract and ureteral stenosis...
July 29, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28756610/treatment-of-obesity-associated-overactive-bladder-by-the-phosphodiesterase-type-4-inhibitor-roflumilast
#14
Honglin Ding, Ning Li, Xiaoning He, Bing Liu, Liming Dong, Yili Liu
PURPOSE: To prove that phosphodiesterase type-4 inhibitors could potentially treat obesity-associated overactive bladder through modulation of the systemic inflammatory response. METHODS: In this 12-week study, 90 female Sprague-Dawley rats were divided into three groups: (1) vehicle-treated normal diet (ND)-fed rats; (2) vehicle-treated high-fat diet (HFD)-fed rats; and (3) roflumilast-treated HFD-fed rats. Oral roflumilast (5 mg/kg/day) was administered during the last 4 weeks of HFD feeding in the test group...
July 29, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28756609/alternative-renal-biopsies-past-and-present
#15
REVIEW
Li Zhuo, Haifeng Wang, Dapeng Chen, Haitao Lu, Guming Zou, Wenge Li
Renal biopsy techniques have been used commonly worldwide for more than 70 years. They play an important role in the diagnosis, treatment, and prognosis of various renal diseases. Percutaneous renal biopsy (PRB) is currently the most important and widely used renal biopsy method. Although >90% of renal biopsies are PRBs, in certain settings, alternative renal biopsy techniques must be used, such as open, laparoscopic, transjugular, and transurethral renal biopsies. This review describes the history, advantages, and disadvantages of the various renal biopsy methods and discusses their current and future uses...
July 29, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28748494/high-glucose-stimulates-cell-proliferation-and-collagen-iv-production-in-rat-mesangial-cells-through-inhibiting-ampk-katp-signaling
#16
Bei Zhang, Yong-Quan Shi, Jun-Jie Zou, Xiang-Fang Chen, Wei Tang, Fei Ye, Zhi-Min Liu
PURPOSE: The present study investigated the putative mechanisms underlying effects of KATP channel on high glucose (HG)-induced mesangial cell proliferation and tissue inhibitors of metalloproteinases (TIMP)-2 and Collagen IV production. METHODS: Rat mesangial cells were subjected to whole cell patch clamp to record the KATP channel currents under high glucose (HG, 30 mM) condition. Cell proliferation was measured using a CCK-8 assay. The production of TIMP-2 and Collagen IV and AMP-activated protein kinase (AMPK)-signaling pathway activity was assessed by ELISA and Western blotting, respectively...
July 26, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28744758/gitelman-syndrome-an-analysis-of-the-underlying-pathophysiologic-mechanisms-of-acid-base-and-electrolyte-abnormalities
#17
REVIEW
T D Filippatos, C V Rizos, E Tzavella, M S Elisaf
Gitelman syndrome is the most common inherited tubular disease resulting from mutations of the SLC12A3 gene that encodes the thiazide-sensitive sodium-chloride cotransporter in the early distal convoluted tubules. The review presents the underlying pathophysiologic mechanisms of acid-base and electrolyte abnormalities observed in patients with Gitelman syndrome. The syndrome is usually characterized by hypokalemic metabolic alkalosis in combination with hypomagnesemia and hypocalciuria. Additionally, increased chloride excretion and renin/aldosterone levels, hypophosphatemia (occasionally), hyponatremia (rarely) and glucose intolerance/insulin resistance have been reported...
July 25, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28741090/direct-comparison-of-tadalafil-with-sildenafil-for-the-treatment-of-erectile-dysfunction-a-systematic-review-and-meta-analysis
#18
Binbin Gong, Ming Ma, Wenjie Xie, Xiaorong Yang, Yongming Huang, Ting Sun, Yanping Luo, Jiao Huang
AIMS: Erectile dysfunction (ED) is a major care problem worldwide. Tadalafil and sildenafil are the two most common phosphodiesterase 5 inhibitors used to treat ED. This systematic review and meta-analysis were conducted to directly compare tadalafil with sildenafil for the treatment of ED. METHODS: We designed a strategy for searching the PubMed, Embase, EBSCO, Web of Science and Cochrane library databases; the reference lists of the retrieved studies were also investigated...
July 24, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28733768/estimates-of-health-utility-scores-in-chronic-kidney-disease
#19
Nigar Sekercioglu, Bryan Curtis, Sean Murphy, Gord Blackhouse, Brendan Barrett
INTRODUCTION: Coverage decisions in publicly funded healthcare systems require a formal, systematic and transparent assessment process for policies related to distribution of resources. The process is complex and employs multiple types of information, such as clinical effectiveness, costs and health utility scores which are used to produce quality-adjusted life years. The purpose of this study was to create health utility scores for CKD patients within the Canadian population. METHODS: This is a cross-sectional study of CKD patients...
July 21, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28733767/relationship-between-plasma-pentraxin-3-level-and-risk-of-chronic-kidney-disease-in-the-korean-elderly-the-dong-gu-study
#20
Ran Lee, Min-Ho Shin, Hee-Nam Kim, Young-Hoon Lee, Seong-Woo Choi, Hye-Ran Ahn, Sun-Seog Kweon
Purpose This study investigated the cross-sectional association between chronic kidney disease (CKD) and plasma pentraxin 3 (PTX3) levels in a Korean population, in a community-based cohort study. METHODS: A total of 1816 (891 men, 925 women) subjects were randomly selected from the cohort of participants for the final analyses. Plasma PTX3 concentration was determined using enzyme-linked immunosorbent assays. The participants were divided into four quartiles according to the PTX3 levels...
July 21, 2017: International Urology and Nephrology
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