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International Urology and Nephrology

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https://www.readbyqxmd.com/read/28439680/microbiological-evaluation-of-infected-pelvic-lymphocele-after-robotic-prostatectomy-potential-predictors-for-culture-positivity-and-selection-of-the-best-empirical-antimicrobial-therapy
#1
Alaa Hamada, Catalina Hwang, Jorge Fleisher, Ingolf Tuerk
OBJECTIVES: To examine symptomatology and microbiology of infected lymphocele (LC) post-robotic-assisted radical prostatectomy and pelvic lymph node dissection (PLND) and to assess for potential predictors for LC fluid culture positivity. Secondly, to provide general recommendations about use of select antimicrobial therapy. METHODS: This was a single-center, IRB-approved, retrospective, case series review conducted between October 2008 and October 2014. Data included symptomatology, microbiology of symptomatic LC in men post-robotic prostatectomy and PLND...
April 24, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28432607/impact-of-the-medical-specialty-on-knowledge-regarding-multidrug-resistant-organisms-and-strategies-toward-antimicrobial-stewardship
#2
Steffen Lebentrau, Christian Gilfrich, Malte W Vetterlein, Harald Schumacher, Philipp J Spachmann, Sabine D Brookman-May, Hans M Fritsche, Martin Schostak, Florian M Wagenlehner, Maximilian Burger, Matthias May
PURPOSE: Evidence is scarce on subject-specific knowledge of multidrug-resistant organisms and rational use of antibiotics. We aimed at evaluating attitude, perception, and knowledge about multidrug-resistant organisms (MDRO) and antibiotic prescribing among urologists versus other medical specialties. METHODS: Within the MR2-study (Multiinstitutional Reconnaissance of practice with MultiResistant bacteria), a questionnaire was conducted targeting general surgeons, internists, gynecologists, and urologists in 18 German hospitals...
April 21, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28432606/neuromuscular-electrostimulation-a-new-therapeutic-option-to-improve-radio-cephalic-arteriovenous-fistula-maturation-in-end-stage-chronic-kidney-disease-patients
#3
Lucia Martinez, Vicent Esteve, Montserrat Yeste, Vicent Artigas, Secundino Llagostera
BACKGROUND: Radio-cephalic arteriovenous fistula (RCAVF) is the gold standard vascular access for end-stage chronic kidney disease patients. Exercises after arteriovenous fistula (AVF) creation improve maturation. No articles are published regarding neuromuscular electrostimulation (NMES) in AVF maturation. OBJECTIVES: To assess the usefulness of a NMES programme on RCAVF maturation process. METHODS: An 8-week single-centre prospective study...
April 21, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28425078/involvement-of-interstitial-cells-of-cajal-in-bladder-dysfunction-in-mice-with-experimental-autoimmune-encephalomyelitis
#4
Zhibo Jin, Yinghui Ding, Rui Xue, Zhankui Jia, Zhenlin Huang, Yafei Ding, Chaohui Gu, Jinjian Yang
BACKGROUND: Bladder dysfunction is an important symptom of experimental autoimmune encephalomyelitis (EAE). Our previous study showed that EAE-induced upregulation of the E-prostanoid receptor 3 (EP3) and E-prostanoid receptor 4 (EP4) in the bladder was accompanied by bladder dysfunction. Although many other studies have evaluated the lower urinary tract symptoms in multiple sclerosis, the mechanism remains unclear. OBJECTIVES: To investigate the effects of interstitial cells of Cajal (ICC) on bladder dysfunction in a novel neurogenic bladder model induced by experimental autoimmune encephalomyelitis...
April 19, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28425077/unexpected-and-striking-effect-of-heparin-free-dialysis-on-cytokine-release
#5
Alicja Rydzewska-Rosolowska, Joanna Gozdzikiewicz-Lapinska, Jacek Borawski, Ewa Koc-Zorawska, Michal Mysliwiec, Beata Naumnik
Heparin (both unfractionated and low molecular weight) is not only a potent anticoagulant but also has many pleiotropic effects, some of which are mediated by cytokine release. We compared the effect of hemodialysis (HD) with enoxaparin as an anticoagulant and without systemic anticoagulation (heparin-grafted membrane-Evodial) on the release of monocyte chemoattractant protein 1 (MCP-1), endostatin (ES) and activin A (Act-A). Nineteen stable HD patients were dialyzed with or without heparin, and plasma levels of MCP-1, ES and Act-A were measured after such a dialysis...
April 19, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28425076/monoclonal-gammopathy-of-renal-significance-mgrs-the-characteristics-and-significance-of-a-new-meta-entity
#6
REVIEW
Mariana Ciocchini, Jorge Arbelbide, Carlos G Musso
Monoclonal gammopathy of renal significance (MGRS) is a new nosological group of entities (meta-entity) defined in 2012, whose pathogenesis depends on monoclonal immunoglobulins (Ig) secreted by low-grade lymphoproliferative disorders, which belong to M-protein-related diseases. Renal damage is the result of monoclonal Ig deposit or its activity as autoantibodies, which can compromise any nephronal area. MGRS does not include kidney diseases produced by high-grade lymphoproliferative disorders as well as those whose pathogenesis are independent of monoclonal Ig (such as drug toxicity or metabolic disorders)...
April 19, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28421393/modified-nomogram-for-derivation-of-renal-threshold-phosphate-concentration
#7
LETTER
Mustafa Tosur
No abstract text is available yet for this article.
April 18, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28421392/combination-of-sacral-nerve-and-tibial-nerve-stimulation-for-treatment-of-bladder-overactivity-in-pigs
#8
Xing Li, Limin Liao, Guoqing Chen, Zhaoxia Wang, Han Deng
PURPOSE: Sacral nerve and tibial nerve stimulation have been singly used to treat overactive bladder (OAB). This study evaluated the effects of both combined stimulation on treating bladder overactivity in pigs and explored a novel treatment modality for OAB. METHODS: An implant-driven stimulator of the S3 spinal nerve was implanted in 5 pigs. The contralateral tibial nerve was stimulated by an external stimulator. Multiple cystometrograms were performed to determine the effects of single nerve stimulation and combination sacral nerve stimulation (SNS) and tibial nerve stimulation (TNS) on the micturition reflex by infusing normal saline (NS) or acetic acid (AA)...
April 18, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28417342/adipose-tissue-derived-stem-cell-therapy-for-erectile-dysfunction-in-rats-a-systematic-review-and-meta-analysis
#9
REVIEW
Quan-Liang Hou, Meng-Ying Ge, Cheng-da Zhang, Dan-Dan Tian, Lian-Ke Wang, Hui-Zi Tian, Wen-Hua Wang, Wei-Dong Zhang
OBJECTIVE: We aimed to systematically assess the effect of adipose tissue-derived stem cell (ADSC) therapy and its influential factors on the treatment of erectile dysfunction (ED) in rats. METHODS: Two authors independently searched for published studies through PubMed and EMBASE from study inception until August 31, 2016. A meta-analysis was used to combine the effect estimate from the published studies. A subgroup analysis was performed to identify the effect of some influential factors...
April 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28417341/external-validation-of-a-nomogram-including-the-computed-tomography-imaging-score-to-predict-indolent-renal-masses
#10
X Chen, B Wan, D Yang, H Zhao, W Tan
PURPOSE: To assess a nomogram including the computed tomography (CT) score and body mass index (BMI) that was constructed to predict indolent diseases in a cohort of patients with renal masses. MATERIALS AND METHODS: The data collected from patients undergoing partial nephrectomy (PN) or radical nephrectomy (RN) between January 2012 and September 2016 were analyzed. Two urologic surgeons and a radiologist reviewed the images to determine the CT score. Postoperative pathological assessment was performed to categorize renal masses as either indolent or aggressive...
April 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28417340/preconditioning-of-primary-human-renal-proximal-tubular-epithelial-cells-without-tryptophan-increases-survival-under-hypoxia-by-inducing-autophagy
#11
Theodoros Eleftheriadis, Georgios Pissas, Maria Sounidaki, Nikolaos Antoniadis, Georgia Antoniadi, Vassilios Liakopoulos, Ioannis Stefanidis
PURPOSE: Hypoxia plays a significant role in the pathogenesis of acute kidney injury (AKI). Autophagy protects from AKI. Amino acid deprivation induces autophagy. The effect of L-tryptophan depletion on survival and autophagy in cultures of renal proximal tubular epithelial cells (RPTECs) under hypoxia was evaluated. METHODS: RPTECs were preconditioned in a medium containing or not tryptophan, following culture under hypoxia and treatment with or without the autophagy inhibitor chloroquine...
April 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28417339/expression-and-function-of-the-small-conductance-ca-2-activated-k-channel-is-decreased-in-urinary-bladder-smooth-muscle-cells-from-female-guinea-pig-with-partial-bladder-outlet-obstruction
#12
Ning Li, Honglin Ding, Xiaoning He, Zizheng Li, Yili Liu
PURPOSE: Overactive bladder (OAB), usually accompanied by partial bladder outlet obstruction (PBOO), is associated with detrusor overactivity (DO) which is related to the increased urinary bladder smooth muscle (UBSM) cells excitability. Small-conductance Ca(2+)-activated K(+) (SK) channels play a constitutive regulatory role of UBSM excitability and contractility. PBOO is associated with the decreased SK channels mRNA expression and the attenuated regulative effect of SK channels on UBSM contractility...
April 17, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28409403/effectiveness-of-beraprost-sodium-in-maintaining-vascular-access-patency-in-patients-on-hemodialysis
#13
Miyeon Kim, Ji Ung Kim, So Mi Kim, HyunWoo Kim
PURPOSE: Hemodialysis vascular access dysfunction, mostly attributed to neointimal hyperplasia, is a major cause of morbidity and hospitalization in patients on hemodialysis. It has been reported that prostaglandin I2 has pleiotropic effects including anti-platelet, vasodilating, anti-inflammatory, and anti-atherogenic properties. In addition, several studies have shown that prostaglandin I2 can inhibit neointimal formation after vascular injury. This study aimed to investigate the effects of beraprost sodium, an oral synthetic analog of prostaglandin I2, on vascular access patency in patients on hemodialysis who experienced primary hemodialysis vascular access failure...
April 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28409402/clinical-evaluation-of-tamsulosin-in-the-relief-of-lower-urinary-tract-symptoms-in-advanced-prostate-cancer-patients
#14
Tong Zhang, Haihu Wu, Shuai Liu, Wei He, Kejia Ding
PURPOSE: To assess the effectiveness and safety of tamsulosin combined with androgen deprivation therapy (ADT) for lower urinary tract symptoms (LUTS) in advanced prostate cancer (PC) patients. METHODS: Ninety PC patients with moderate-to-severe LUTS randomized into two groups of 45 each. One group received ADT (group 1), and the other received ADT plus tamsulosin (group 2) for 24 weeks. The outcome measures were changes in the International Prostate Symptom Score (IPSS), IPSS obstructive and irritative subscores, quality of life (QoL), maximum urinary flow rate (Q max), post-voiding residual (PVR) and prostate-specific antigen (PSA) from baseline...
April 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28401380/fate-of-newly-developed-pulmonary-embolism-after-surgery-for-renal-cell-carcinoma-with-vena-cava-thrombus
#15
Sangjun Yoo, Sang Hoon Song, Heounjeong Go, Dalsan You, Cheryn Song, Jun Hyuk Hong, Choung-Soo Kim, Hanjong Ahn, In Gab Jeong
PURPOSE: Pulmonary embolism with viable tumor cells developed after surgery for renal cell carcinoma may metastasize to lung. We investigated the incidence and fate of newly developed pulmonary embolism after surgery for renal cell carcinoma with vena cava thrombus. METHODS: Among 4549 renal cell carcinoma patients treated with curative surgery at our institute from 1998 to 2015, 81 non-metastatic renal cell carcinoma patients with vena cava thrombus were included...
April 11, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28401379/kidney-lung-pathophysiological-crosstalk-its-characteristics-and-importance
#16
REVIEW
Pilar Domenech, Tomas Perez, Agustina Saldarini, Pedro Uad, Carlos G Musso
Crosstalk between the lung and the kidney is based on the similarities that these organs share. This is why different diseases that affect one organ can have repercussions on the other. Patients with acute kidney injury can present complications such as pulmonary edema and require mechanical ventilation in respiratory failure. This interaction occurs due to the increase in systemic immune mediators that cause inflammatory reactions, oxidative stress, and an increase in vascular permeability in the lung. With regard to lung-induced renal damage, the kidney can also be affected by chemical mediators, which are translocated into the bloodstream...
April 11, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28386744/impact-of-chronic-kidney-disease-among-korean-adults-with-chronic-obstructive-pulmonary-disease
#17
Min Young Kim, Sungmin Boo, Mijung Yoo, Jonghyun Lee, Na Ree Kang
PURPOSE: Chronic kidney disease (CKD) is an emerging issue in patients with chronic obstructive pulmonary disease (COPD). In COPD, loss of muscle mass is relatively common finding, and diagnosis of CKD should be based on measured or estimated GFR (Cavailles et al. Eur Respir Rev 22:454-475, 2013; Gosker et al. Am J Clin Nutr 71:1033-1047, 2000; Delanaye and Mariat Nat Rev Nephrol 9:513-522, 2013). We aimed to determine the prevalence and impact of CKD, defined by using chronic kidney disease epidemiology collaboration (CKD-EPI) equation, in COPD patients...
April 6, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28382576/in-vivo-human-corpus-cavernosum-regeneration-fabrication-of-tissue-engineered-corpus-cavernosum-in-rat-using-the-body-as-a-natural-bioreactor
#18
Abdol-Mohammad Kajbafzadeh, Reza Abbasioun, Nastaran Sabetkish, Shabnam Sabetkish, Ali Akbar Habibi, Kamyar Tavakkolitabassi
PURPOSE: Few researches have been conducted to develop an ideal method for tissue engineering of corpus cavernosum. We produce a decellularized human corpus cavernosum scaffold and investigate the in vivo cell seeding of the scaffold after transplantation into the rat omentum. METHODS: Eight adult human male corpus cavernosum were obtained in sterile condition. After dissecting the urethra, corpus cavernosum was decellularized by inserting an 18-gauge needle into the body of the tissue...
April 5, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28382575/erratum-to-dietary-and-commercialized-fructose-sweet-or-sour
#19
Aslihan Yerlikaya, Tuncay Dagel, Christopher King, Masanari Kuwabara, Miguel A Lanaspa, Ana Andres-Hernando, Adrian Covic, Jacek Manitius, Alan A Sag, Mehmet Kanbay
No abstract text is available yet for this article.
April 5, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28361474/metabolic-syndrome-is-predictive-of-lower-urinary-tract-symptom-improvement-after-holmium-laser-enucleation-of-the-prostate-for-benign-prostatic-obstruction
#20
Taekmin Kwon, Sejun Park, Sungchan Park, Kyung Hyun Moon
PURPOSE: To investigate the effect of metabolic syndrome (MS) on patient outcomes who underwent holmium laser enucleation of the prostate (HoLEP) for benign prostatic obstruction. MATERIALS AND METHODS: Data from 151 patients who underwent HoLEP by a single surgeon between March 2012 and March 2016 were retrospectively analyzed. Patients with MS were assigned to group 1 (n = 33) and patients without MS in group 2 (n = 118). Clinical characteristics and the International Prostate Symptom Score (IPSS), including quality of life (QoL), peak urinary flow rate (Qmax), and postvoid residual urine (PVR), before surgery and 3 months afterward were compared between groups...
March 30, 2017: International Urology and Nephrology
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