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International Urology and Nephrology

Qi Huang, Yunshuang Chen, Min Zhang, Sihe Wang, Weiguang Zhang, Guangyan Cai, Xiangmei Chen, Xuefeng Sun
PURPOSE: We compared the performance of technetium-99m-diethylenetriaminepentaacetic acid (99m Tc-DTPA) renal dynamic imaging (RDI), the MDRD equation, and the CKD EPI equation to estimate glomerular filtration rate (GFR). METHODS: A total of 551 subjects, including CKD patients and healthy individuals, were enrolled in this study. Dual plasma sample clearance method of99m Tc-DTPA was used as the true value for GFR (tGFR). RDI and the MDRD and CKD EPI equations for estimating GFR were compared and evaluated...
February 20, 2018: International Urology and Nephrology
Congyun Xu, Yan Xu, Zhou Shen, Hangcheng Zhou, Jun Xiao, Tao Huang
OBJECTIVES: To investigate the efficacy of insulin sensitizer on prostatic tissue in animal model with benign prostatic hyperplasia (BPH) secondary to metabolic syndrome (MetS). METHODS: Models were established by providing Sprague-Dawley rats with high fat diet (HFD) combined with metformin or not. All objects were killed 40 days later with prostatic tissue being removed, weighed before stained, as well as the expression level of insulin-like growth factor I (IGF-1) and receptor (IGF-1R) being measured, and the level of insulin resistance (IR) has also been evaluated...
February 19, 2018: International Urology and Nephrology
Fan He, Zhenxing Yang, Xingyou Dong, Zhenqiang Fang, Qian Liu, Xiaoyan Hu, Shanhong Yi, Longkun Li
OBJECTIVE: To explore the role of HCN channels in ureteral peristaltic dysfunction by comparing the changes in HCN channel levels between normal and tuberculous ureters. METHODS: A total of 32 specimens of human upper ureters were collected by nephrectomy from patients with renal tumor (control group, n = 16) or from patients with renal tuberculosis (experimental group, n = 16); the two groups did not receive radiotherapy, chemotherapy, immunotherapy, or any other special treatment before the surgical procedure...
February 19, 2018: International Urology and Nephrology
Quan Wang, Wei-Yang He, Yi-Zhou Zeng, Arman Hossain, Xin Gou
BACKGROUND: This study investigates the docetaxel-resistant mechanism and explores the effect of tea polyphenols (TP) on autophagy and its related mechanism in human castration-resistant prostate cancer (CRPC) cell lines PC3 and DU145. METHODS: Immunofluorescence assay and annexin V-FITC/PI double staining flow cytometry were used to analyze the apoptosis and autophagy of PC3 and DU145 cells. The expression of autophagy-related proteins was detected by western bolt...
February 19, 2018: International Urology and Nephrology
Nada Dimkovic, Georg Schlieper, Aleksandar Jankovic, Zivka Djuric, Marcus Ketteler, Tatjana Damjanovic, Petar Djuric, Jelena Marinkovic, Zoran Radojcic, Natasa Markovic, Jürgen Floege
PURPOSE: Cardiovascular calcifications (CVC) are present in up to 70% of non-diabetic dialysis patients. Sparse data are available on predictors of very long-term outcomes of such patients. The Belgrade Aachen Study on Calcification in Hemodialysis patients (BASCH study) aimed to study this using a comprehensive CVC assessment. METHODS: We prospectively analyzed 220 hemodialysis patients followed for a mean of 76 months (median 73 months, range 6-160 months). We compared patients deceased from cardiovascular diseases (CVD) and survivors...
February 13, 2018: International Urology and Nephrology
Maria Chiara Sighinolfi, Bernardo Rocco, Salvatore Micali, Gabriella Orlando, Claudia Venturelli, Cristina Mussini, Giampaolo Bianchi
No abstract text is available yet for this article.
February 13, 2018: International Urology and Nephrology
Steffen Lebentrau, Christian Gilfrich, Malte W Vetterlein, Harald Schumacher, Philipp J Spachmann, Sabine D Brookman-May, Hans M Fritsche, Martin Schostak, Florian M Wagenlehner, Maximilian Burger, Matthias May
No abstract text is available yet for this article.
February 13, 2018: International Urology and Nephrology
Meng Wang, Si-Yi Yu, Zheng-Tao Lv, Ying Yao
PURPOSE: To investigate and quantify the potential association between betel nut chewing and the risk of chronic kidney disease (CKD). METHODS: We searched five online databases including PubMed, EMBASE, ISI Web of Science, Wanfang and CNKI to identify observational studies that published prior to May, 1, 2017. The primary outcome was the association between betel nut chewing and CKD expressed as odds ratio (OR) and the corresponding 95% confidence interval (95%CI) after adjustment for other covariates...
February 13, 2018: International Urology and Nephrology
Nissar Ahmed Sheikh, Mohammed Hassan Khan, Sanjay Pillai, Stephen Lang, Ghulam Nabi
OBJECTIVES: To report longitudinal outcomes of a population-based cohort of patients diagnosed with bilateral small renal masses from a period of over 11 years. PATIENTS AND METHODS: Consecutive patients diagnosed with bilateral small renal masses (synchronous or metachronous) of a defined geographical area were recorded in a large database (TUCAN database) between January 2005 and December 2016. Patients had a unique identifier number and followed during this period using an agreed upon protocol...
February 10, 2018: International Urology and Nephrology
Rachael Dana Sussman, Krishnan Venkatesan
No abstract text is available yet for this article.
February 8, 2018: International Urology and Nephrology
Marco Cosentino, Maria F Peraza, Alvaro Vives, Josvany Sanchez, Daniel Moreno, Judith Perona, Gerardo Ortiz, Maria Alcoba, Eduardo Ruiz, Joaquim Sarquella
PURPOSE: To identify factors predicting success and analyze critically the status of microsurgical double-layer vasovasostomy using predictive models. METHODS: A cohort of 263 patients treated at our institution for vasectomy reversal between 1986 and 2010 was included in our study, and the literature was reviewed. Inclusion criteria were previous bilateral vasectomy and presence of at least two postoperative semen analyses; patients reporting pregnancy without a postoperative semen analysis were excluded...
February 8, 2018: International Urology and Nephrology
Wen-Qi Ma, Yu Zhao, Ying Wang, Xi-Qiong Han, Yi Zhu, Nai-Feng Liu
BACKGROUND: Contrast-induced nephropathy (CIN) is the major complication related to contrast media administration in patients after coronary angiography (CAG). However, inconsistent results have been published in the literature regarding the effects of pharmacological drugs on CIN prevention. We conducted a network meta-analysis to evaluate the relative efficacy of pharmacological interventions for the prevention of CIN. METHODS: We searched MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and ClinicalTrials...
February 5, 2018: International Urology and Nephrology
Jielong Jiang, Lijun Ni, Wei Ren, Xiaowan Zhou, Keliang Su, Lihua Wang, Lei Lan, Wei Chen, Yuanbo Wu
PURPOSE: Malnutrition is the main determinant of mortality and morbidity in maintenance hemodialysis patients. In many countries except for China, it has been reported that short daily hemodialysis (SDHD) could improve nutritional status. We will report here the nutritional results obtained in the SDHD therapy period compared with conventional hemodialysis (cHD) therapy period in Chinese patients. METHODS: This study compared 29 SDHD patients (SDHD group), each patient served as his own control, with 30 cHD patients (cHD group) serving as the parallel controls...
February 5, 2018: International Urology and Nephrology
Adriana Martini, Adriano Ammirati, Carlos Garcia, Carolina Andrade, Odete Portela, Maysa S Cendoroglo, Ricardo Sesso
PURPOSE: The diagnosis of chronic kidney disease (CKD) in elderly individuals has been increasing. The objective of this study was to evaluate physical, mental and social aspects in longevous elderly patients with CKD. METHODS: Eighty patients with CKD (stage 4 and 5, not on dialysis) and 60 longevous elderly (≥ 80 years) paired by gender and age living in the community were evaluated. Physical, cognitive, social and quality of life aspects were analyzed according to the following scales: Charlson comorbidity index, Medical Outcomes Study Short Form 36-Item (SF-36), Medical Outcomes Study, Boston Naming Test, verbal fluency test (animal naming), sit-to-stand test, gait speed, and the Mini-Mental state examination...
February 5, 2018: International Urology and Nephrology
Farrukh M Koraishy, Denise Hooks-Anderson, Joanne Salas, Michael Rauchman, Jeffrey F Scherrer
BACKGROUND: Fast glomerular filtration rate (GFR) decline is associated with adverse outcomes, but the associated risk factors among patients without chronic kidney disease (CKD) are not well defined. METHODS: From a primary care registry of 37,796, we identified 2219 (6%) adults with at least three estimated (e)GFR values and a baseline eGFR between 60 and 119 ml/min/1.73 m2 during an observation period of 8 years. We defined fast GFR decline as > 5 ml/min/1...
February 5, 2018: International Urology and Nephrology
Tao Wang, Yan Zhang, Ning Wang, Qiong Liu, ZeKai Wang, Bing Liu, Kai Niu
PURPOSE: Since altered sympathetic nerve activity and insulin resistance are implicated in the pathogenesis of type 2 diabetic nephropathy, we investigated the effect of polymorphic Arg16Gly and Gln27Glu in the β2 adrenoceptor gene and Ala54Thr in the fatty acid binding protein 2 gene on the estimated glomerular filtration rate (eGFR) in Chinese patients with the above disease. METHODS: A total of 552 diabetic subjects recruited from annual health examinations were studied...
February 5, 2018: International Urology and Nephrology
Waseem Aboulela, Mohammed S ElSheemy, Mahmoud Shoukry, Ahmed M Shouman, Ahmed I Shoukry, Waleed Ghoneima, Mohamed El Ghoneimy, Hany A Morsi, Mostafa Abdel Mohsen, Hesham Badawy
PURPOSE: To compare efficacy and safety of visual internal urethrotomy (VIU) using holmium laser (Ho:YAG) (group A) versus cold knife (group B) in children with urethral strictures. It may be the first comparative study on this issue in children. METHODS: This study compared Ho:YAG group, which was evaluated prospectively from January 2014 till January 2016, versus cold knife group, which was a historical control performed from March 2008 till February 2010. Children ≤ 13 years old with urethral strictures ≤ 1...
February 3, 2018: International Urology and Nephrology
C Chahwan, P A Turcanu, F Alharbi, L Vaudreuil, A L Fiant, K Guleryuz, G Leon, X Tillou, A Doerfler
OBJECTIVE: To determinate feasibility and results of the flush technique by hands for the surgical management of renal cell carcinoma (RCC) with levels III and IV inferior vena cava thrombus (VCT). MATERIALS AND METHODS: We conducted a retrospective study for all patients who underwent a surgical treatment for RCC with levels III and IV VCT in our department between June 2010 and July 2017. Sixteen patients were identified. RESULTS: All tumors were resected using a subcostal incision for right RCC and a chevron incision for the left RCC...
February 1, 2018: International Urology and Nephrology
Pradeep Tyagi, Joseph Janicki, Chan-Hong Moon, Jonathan Kaufman, Christopher Chermansky
PURPOSE: Instillation of novel contrast mixture (NCM) was recently shown to improve the contrast resolution of rat bladder wall with high contrast-to-noise ratio (CNR). Here, the clinical safety and the feasibility of NCM-enhanced MRI to achieve artifact-free visualization of human bladder wall suitable for quantitative measurement of the magnetic resonance (MR) longitudinal relaxation time (T1) was assessed. METHODS: Six female subjects [two controls and two with Hunner-type interstitial cystitis IC and two with non-Hunner-type IC] consented for MRI at 3 T before and after instillation of NCM [4 mM gadobutrol and 5 mM ferumoxytol in 50 mL of sterile water for injection]...
February 1, 2018: International Urology and Nephrology
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