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International Urology and Nephrology

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https://www.readbyqxmd.com/read/29027620/evaluation-of-the-tolerability-and-efficacy-of-sodium-polystyrene-sulfonate-for-long-term-management-of-hyperkalemia-in-patients-with-chronic-kidney-disease
#1
Panagiotis I Georgianos, Ioannis Liampas, Andreas Kyriakou, Vasilios Vaios, Vasilios Raptis, Nikolaos Savvidis, Athanasios Sioulis, Vassilios Liakopoulos, Elias V Balaskas, Pantelis E Zebekakis
PURPOSE: Sodium polystyrene sulfonate (SPS) is a cation-exchanging resin that has been widely used for several decades as first-line therapy of mild chronic hyperkalemia in patients with chronic kidney disease (CKD). However, evidence to prove the long-term tolerability and efficacy of SPS for the treatment of this condition is still missing. METHODS: In this retrospective, observational study, we enrolled 26 outpatients with stages 3-4 CKD who received oral therapy with low-dose SPS for mild chronic hyperkalemia in the Outpatient Nephrology clinic of our Department during 2010-2016...
October 11, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29027072/outcomes-of-acute-kidney-injury-in-a-nephrology-ward
#2
Ana R Fernandes, Márcio S R Viegas, Elsa Q Soares, Sofia S Coelho, Patricia Valério, José C Barreto, José M Vinhas
Acute kidney injury (AKI) is a global problem which predicts immediate and long-term adverse outcomes. We evaluated the AKI progression to end-stage renal disease, as well as the mortality associated with AKI and the in-hospital readmission rate because of a cardiovascular event in AKI patients admitted in a nephrology ward. A 5-year retrospective study was set in a nephrology department, with a follow-up period of up to 8 years. In a total of 191 patients, mean age was 73.83 ± 12.49 years, and 137 (71...
October 11, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28975489/use-of-lung-ultrasonography-to-determine-the-accuracy-of-clinically-estimated-dry-weight-in-chronic-hemodialysis-patients
#3
Chuan Jiang, Satyam Patel, Andrew Moses, Maria V DeVita, Michael F Michelis
PURPOSE: The use of lung ultrasound (LUS) to identify extravascular lung water has received increasing acceptance. Sonographic B-lines, discrete vertical lines that originate from the pleura, represent pulmonary edema and are correlated with the accumulation of fluid. The goal of this study was to evaluate the utility of LUS to determine the accuracy of prescribed dry weight (DW) in chronic hemodialysis (HD) patients and to ascertain the adequacy of fluid removal. METHODS: LUS was scheduled to be performed pre- and post-HD in 20 patients...
October 3, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28975469/establishment-of-a-bioluminescent-renca-cell-line-for-renal-carcinoma-research
#4
Jie Ding, Chao Wang, Xiaofeng Chang
PURPOSE: Luciferase modification of tumour cells enables early and non-invasive imaging to detect tumour growth in situ and could provide sensitive and effective detection of carcinoma during research and therapy. METHODS: Renca cells, a murine renal carcinoma cell line, were infected with lentivirus expressing luciferase to obtain Renca-luc. The proliferation, invasion, and migration of Renca and Renca-luc cell lines were compared using colorimetric, Boyden chamber, and wound-healing assays...
October 3, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28975468/effect-of-restricted-protein-diet-supplemented-with-keto-analogues-in-end-stage-renal-disease-a-systematic-review-and-meta-analysis
#5
REVIEW
Zheng Jiang, Yi Tang, Lichuan Yang, Xuhua Mi, Wei Qin
AIM: To evaluate the efficacy and safety of the restricted protein diet supplemented with keto analogues when applied in end-stage renal disease (ESRD). METHODS: The Cochrane Library, PubMed, Embase, CBM and CENTRAL databases were searched and reviewed up to January 2017. Clinical trials were analyzed using RevMan 5.3 software. RESULTS: Five randomized controlled trials were selected and included in this study according to our inclusion and exclusion criteria...
October 3, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28965299/value-of-bioimpedance-analysis-estimated-dry-weight-in-maintenance-dialysis-patients-a-systematic-review-and-meta-analysis
#6
Adrian Covic, Adi-Ionut Ciumanghel, Dimitrie Siriopol, Mehmet Kanbay, Raluca Dumea, Cristina Gavrilovici, Ionut Nistor
BACKGROUND: Volume overload is a common complication in patients with end-stage kidney disease who undergo maintenance dialysis therapy and associated with hypertension, left ventricular hypertrophy and mortality in this population. Although bioimpedance analysis (BIA), an objective method to assess overhydration, is associated with poor outcomes in observational studies, in randomized controlled trials (RCTs) the results were conflicting. We have examined the role of BIA for assessing the "dry weight" and fluid status in order to improve fluid overload in comparison with a control or clinical-based prescription in patients with ESKD receiving haemodialysis or peritoneal dialysis...
September 30, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28956280/management-of-urinary-tract-infection-with-intravesical-amikacin-may-increase-the-risk-of-bladder-oxidative-stress-in-children-with-neurogenic-bladder
#7
Akin Soner Amasyali, Dilek Yilmaz, Mustafa Yilmaz, Faruk Kucukdurmaz, Ferah Sonmez, Haluk Erol
INTRODUCTION: We evaluated the bladder oxidative stress in neurogenic bladder children treated with intravesical amikacin for recurrent UTI and whether urinary isoprostane f2 alpha (F2-IsoP) is a good biomarker in this particular condition. METHODS: This prospectively designed controlled study was approved by the Adnan Menderes University institutional ethics committee (Adnan Menderes University, 2015/649). Between January 2016 and January 2017, twenty-six children with meningomyelocele who had been doing CIC were recruited...
September 27, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28956241/predictive-value-of-procalcitonin-for-diagnosis-of-infections-in-patients-with-chronic-kidney-disease-a-comparison-with-traditional-inflammatory-markers-c-reactive-protein-white-blood-cell-count-and-neutrophil-percentage
#8
Yanbei Sun, Lijuan Jiang, Xiaonan Shao
PURPOSE: To investigate the predictive value of procalcitonin (PCT) in patients with stage 1-4 and stage 5 chronic kidney disease (CKD). METHODS: Five hundred and forty-one CKD inpatients were retrospectively analyzed and divided into CKD stage 1-4 (CKD1-4) and CKD stage 5 (CKD5) groups. Each group was further divided into non-infection, local infection, and sepsis subgroups. The clinical characteristics and inflammatory indexes of each subgroup including PCT, C-reactive protein (CRP), white blood cell count (WBC), and neutrophil percentage (N%) were compared, and the receiver operating characteristic curves to predict local infection and sepsis were plotted...
September 27, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28952068/predictors-of-depression-in-hemodialysis-patients
#9
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
September 26, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28948420/addition-of-silymarin-to-renin-angiotensin-system-blockers-in-normotensive-patients-with-type-2-diabetes-mellitus-and-proteinuria-a-prospective-randomized-trial
#10
Luminita Voroneanu, Dimitrie Siriopol, Raluca Dumea, Silvia Badarau, Mehmet Kanbay, Baris Afsar, Cristina Gavrilovici, Adrian Covic
BACKGROUND: In the last decade, despite constant investigation, no current single treatment has been able to decrease the incidence of diabetic nephropathy and to significantly reduce progression of diabetic CKD. METHODS: Patients with type 2 diabetes mellitus and proteinuria (>0.5 g/day) after a screening and treatment optimization phase were randomly assigned to receive silymarin or placebo. The primary outcome was a composite outcome: mortality, decline of eGFR > 50% and renal replacement therapy...
September 25, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28940112/iron-in-kidney-and-heart-failure-from-theory-to-practice
#11
REVIEW
Aslihan Yerlikaya, Mustafa C Bulbul, Baris Afsar, Tuncay Dagel, Gamze Aslan, Luminita Voroneanu, Dimitire Siriopol, Adrian Covic, Mehmet Kanbay
There is evidence that serum iron levels, regardless of the presence of anemia, directly impact outcomes in congestive heart failure (CHF) including quality of life, hospitalization rate and overall survival. Despite modern medical treatments, the prognosis of CHF remains grim. Ironically, simple iron replenishment may serve as a powerful tool in the armamentarium. This review will start from fundamental concepts of iron in oxygen delivery and analyze evidence-based outcomes in CHF iron-directed therapeutic trials...
September 22, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28939941/kidney-involvement-in-psoriasis-a-case-control-study-from-china
#12
Fang Ren, Min Zhang, Liying Hao, Hong Sang
PURPOSE: Kidney involvement secondary to psoriasis is still a controversial issue. In this study, we aimed to evaluate the prevalence of urinary abnormalities in psoriasis patients and to find out whether the abnormality is related to the severity of psoriasis. METHODS: Ninety-seven psoriasis patients (62 females, 35 males, mean age 35.74 ± 13.45 years) and ninety-six age- and gender-matched control subjects (58 males, 38 females, mean age 35.82 ± 13.48 years) without hypertension or diabetes were enrolled in this study...
September 22, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28936714/prevalence-of-abdominal-artery-calcification-in-dialysis-patients-with-end-stage-renal-disease-a-systematic-review-and-meta-analysis
#13
Zhihui Yao, Congxia Wang, Qiaona Zhang, Shan Ma, Baosong Gui, Chaoyang Duan
PURPOSE: To systematically determine the prevalence of abdominal artery calcification (AAC) in dialysis patients with end-stage renal disease (ESRD) and identify reasons for heterogeneity. METHODS: We searched PubMed, EMBASE, and Web of Science from database inception to March 2017. Cross-sectional or cohort (only used baseline data) studies reporting estimates of AAC prevalence in dialysis adult patients with ESRD were included. We performed a random-effects meta-analysis to generate pooled prevalence estimates...
September 21, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28933020/deriving-a-management-algorithm-for-emphysematous-pyelonephritis-can-we-rely-on-minimally-invasive-strategies-or-should-we-be-opting-for-earlier-nephrectomy
#14
Eve Boakes, Deepak Batura
PURPOSE: To analyse the incidence and management of emphysematous pyelonephritis (EPN) in North West London and examine factors that influence immediate and 6-month outcomes with the aim of guiding future management. METHODS: This work analyses EPN cases from the London North West Healthcare NHS Trust from October 2006 to July 2015 (population ≈ 850,000). Diagnosis and stage were confirmed by computed tomography (CT). Demographic, clinical, biochemical and microbiological characteristics were assessed...
September 20, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28932952/survival-of-metastatic-renal-cell-carcinoma-patients-continues-to-improve-over-time-even-in-targeted-therapy-era
#15
Michele Marchioni, Marco Bandini, Raisa S Pompe, Zhe Tian, Tristan Martel, Anil Kapoor, Luca Cindolo, Francesco Berardinelli, Alberto Briganti, Shahrokh F Shariat, Luigi Schips, Pierre I Karakiewicz
OBJECTIVE: To examine the effect of diagnosis year, defined as contemporary (2010-2014), intermediate (2006-2009) and historical (2001-2005) on cancer-specific mortality (CSM) in patients with metastatic renal cell carcinoma (mRCC). METHODS: Within Surveillance, Epidemiology, and End Results registry (2001-2014), we identified patients with mRCC. Cumulative incidence and competing risks regression (CRR) models examined CSM, after accounting for other-cause mortality...
September 20, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28918580/apropos-use-of%C3%A2-biological-mesh-in%C3%A2-trans-anal-treatment-for%C3%A2-recurrent-recto-urethral-fistula
#16
LETTER
Deepak Batura
No abstract text is available yet for this article.
September 16, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28918524/use-of-biological-mesh-in-trans-anal-treatment-for-recurrent-recto-urethral-fistula
#17
LETTER
Marco Inama
No abstract text is available yet for this article.
September 16, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28918446/favorable-surgical-outcomes-of-aldosterone-producing-adenoma-based-on-lateralization-by-ct-imaging-and-hypokalemia-a-non-avs-based-strategy
#18
Hai Li, Jianbin Liu, Xiujuan Feng, Liehua Liu, Guohong Wei, Xiaopei Cao, Yanbing Li
PURPOSE: To test the efficacy of a strategy based on CT imaging and clinical characteristics on lateralizing origin of excess aldosterone secretion in primary aldosteronism. PATIENTS AND METHODS: Consecutive patients with diagnosed primary hyperaldosteronism from June 2006 to July 2012 in our center underwent adrenal surgeries without pre-operational adrenal venous sampling (AVS) if all the three criteria were met: (1) round- or oval-shaped occupational lesion of low density after contrast enhancement with diameter >1 cm on CT scan was located in one adrenal gland; (2) unequivocally normal contralateral adrenal gland; (3) serum potassium level lower than 3...
September 16, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28917023/a-new-modification-of-the-duckett-technique-for-one-stage-repairing-urethral-plate-transected-hypospadias-another-option-for-severe-hypospadias
#19
Li-Qu Huang, Yun-Fei Guo, Zheng Ge, Ru-Gang Lu, Yong-Ji Deng, Geng Ma, Fang Chen
OBJECTIVES: The study aimed to evaluate the new modification of the Duckett technique in decreasing the incidence of urethral strictures for urethral plate transected hypospadias and also explored its clinical application. METHODS: Thirty-three patients (aged 7 months to 12 years, mean age 2.8 years) who underwent repair of primary hypospadias using the new one-stage urethroplasty were enrolled. Clinical data, including cosmetic and its complications, and uroflowmetry data were documented...
September 15, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28913706/novel-pericatheter-retrograde-urethrogram-technique-is-a-viable-method-for-postoperative-urethroplasty-imaging
#20
Rachael D Sussman, F Cameron Hill, George E Koch, Versha Patel, Krishnan Venkatesan
PURPOSE: The purpose of this study is to describe our technique for pericatheter retrograde urethrogram (pcRUG) and to evaluate the utility of a pcRUG to detect a clinically significant leak after urethral reconstruction. METHODS: We retrospectively reviewed our prospective IRB-approved database of patients undergoing urethral reconstruction. pcRUG was performed at 3-4 weeks after surgery, in standardized fashion. Patients were placed in oblique position, and with the penis stretched, diluted contrast was instilled via an angiocatheter alongside the indwelling urethral catheter under dynamic fluoroscopy...
September 14, 2017: International Urology and Nephrology
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