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Leprosy Review

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https://www.readbyqxmd.com/read/27255072/symposium-on-emerging-needs-in-leprosy-research-in-the-post-elimination-era-the-leprosy-mission-trust-india
#1
Itu Singh, Mallika Lavania, Astha Nigam, Ravindra P Turankar, Madhvi Ahuja, Annamma S John, Utpal Sengupta
No abstract text is available yet for this article.
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255071/thomas-herald-rea-md-1929-2016
#2
Maria T Ochoa, Seth Vaccaro, Robert Jerskey, Helen Mora, David Peng, Robert L Modlin
No abstract text is available yet for this article.
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255070/dr-h-srinivasan-1929-2015
#3
Shaik K Noordeen
No abstract text is available yet for this article.
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255069/cultural-practice-and-beliefs-hampering-the-treatment-of-leprosy-an-area-of-concern
#4
LETTER
Swetalina Pradhan, Piyush Kumar
No abstract text is available yet for this article.
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255068/bone-marrow-evaluation-in-leprosy-clinical-implications
#5
LETTER
Padhi Somanath, Krishna C Vijay
No abstract text is available yet for this article.
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255067/management-of-chronic-neuritis-with-a-combination-regimen-of-lower-doses-prednisolone-and-methotrexate-a-brief-report
#6
LETTER
Delwar Hossain
INTRODUCTION: Recommended fixed duration prednisolone regimen was not found effective in the treatment of chronic neuritis. Alternate effective treatment was being sought to reduce the deformity in the field of leprosy. OBJECTIVE: We wished to see whether a prolonged course of prednisolone and methotrexate could be of any help for them. METHODOLOGY: In 2012-2014, an open pilot clinical study was undertaken where three chronic neuritic patients were treated with lower doses prednisolone and methotrexate for 12 months and a follow up period was delivered for 12 months...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255066/validation-of-the-leprosy-type-1-reaction-severity-scale-in-ethiopia
#7
LETTER
Lambert Saba M, Haroun Omer, Diana N J Lockwood
No abstract text is available yet for this article.
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255065/tuberculosis-and-leprosy-infections-in-the-marshallese-population-of-arkansas-usa
#8
LETTER
Victor Manuel Cardenas, Mohammed S Orloff, Joseph Kaminaga, Irma Carrillo Cardenas, Joeline Brown, Sandra Hainline-Williams, Malcolm S Duthie, Angela C Gonzalez-Puche, Leonard Mukasa, Naveen Patil, Pearl Ann Mcelfish, Joseph H Bates
The cross-immunity between tuberculosis and leprosy is unknown. The aim of this pilot study was to evaluate the occurrence of Mycobacterium tuberculosis and M. leprae infection in Marshallese adult volunteers in Springdale, Arkansas, U.S.A., a population that experiences high rates of leprosy and tuberculosis. We used immunodiagnostic testing for tuberculosis and leprosy infection and found significant prevalence of latent tuberculosis infection (19.0%), and asymptomatic Mycobacterium leprae infection (22.2%)...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255064/the-story-of-a-deformed-leprous-foot
#9
Shaurya Rohatgi, Sushma Naveen, Pranjal Salunke, Shylaja Someshwar, Hemangi Rajiv Jerajani, Rajiv Joshi
Eccrine syringofibroadenoma (ESFA) is a rare adnexal tumour of eccrine ductal proliferation. A 50 year old treated case of leprosy presented with a chronic non healing ulcer of 5 years duration on the deformity laden right foot. Multiple verrucous papules and plaques were seen surrounding the ulcer which showed histopathological findings consistent with ESFA. Although ESFA constitutes a rare association with leprosy, considering the load of treated cases in our country and elsewhere, it may represent an under-reported entity which requires more attention in the post elimination era...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255063/autochthonous-borderline-tuberculoid-leprosy-in-a-man-from-florida
#10
Gabriel Villada, Mina Zarei, Ricardo Romagosa, Patrizia Forgione, Gabriella Fabbrocini, Paolo Romanelli
Leprosy (Hansen's disease) is a chronic contagious granulomatous disease principally affecting the skin and peripheral nervous system, caused by Mycobacterium leprae. In this report, we present a case of autochthonous leprosy in a man from Florida as the first human case reported from this region. Authors believe dermatologists need to be aware of the possibility of autochthonous transmission of leprosy in the Eastern-Southern United States, and should consider leprosy in any patient with atypical skin lesions, even when a history of contact with armadillo is missing...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255062/mutation-at-codon-442-in-the-rpob-gene-of-mycobacterium-leprae-does-not-confer-resistance-to-rifampicin
#11
Mallika Lavania, Abu Hena, Hasanoor Reja, Astha Nigam, Nibir Kumar Biswas, Itu Singh, Ravindra P Turankar, Ud Gupta, Senthil Kumar, Latika Rewaria, Pradip K R Patra, Utpal Sengupta, Basudeb Bhattacharya
BACKGROUND: Rifampicin is the major drug in the treatment of leprosy. The rifampicin resistance of Mycobacterium leprae results from a mutation in the rpoB gene, encoding the β subunit of RNA polymerase. As M. leprae is a non-cultivable organism observation of its growth using mouse food-pad (MFP) is the only Gold Standard assay used for confirmation of "in-vivo" drug resistance. OBJECTIVE: Any mutation at molecular level has to be verified by MFP assay for final confirmation of drug resistance in leprosy...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255061/association-of-viable-mycobacterium-leprae-with-type-1-reaction-in-leprosy
#12
Mrudula Prakash Save, Anju Rajaram Dighe, Mohan Natrajan, Vanaja Prabhakaran Shetty
UNLABELLED: The working hypothesis is that, viable Mycobacterium leprae (M. leprae) play a crucial role in the precipitation of Type 1 reaction (T1R) in leprosy. MATERIAL AND METHODS: A total of 165 new multibacillary patients were studied. To demonstrate presence of viable M. leprae in reactional lesion (T1R+), three tests were used concurrently viz. growth in the mouse foot pad (MFP), immunohistochemical detection of M. leprae secretory protein Ag85, and 16s rRNA--using in situ RT-PCR...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255060/prospective-analytical-study-of-assessment-of-off-loading-by-total-contact-cast-in-treatment-of-non-healing-plantar-ulcers-in-anaesthetic-foot
#13
Siddharth Rai, Anil Kumar Gupta, Dileep Kumar, Vijai Prakash Sharma, Ashok Kumar Agarwal
BACKGROUND: Chronic planter ulcer, also known as trophic ulcer, shows no tendency towards healing. It is usually seen in sensory deficient foot. The clinical result of a sensory, motor or autonomic loss of a nerve function is frequently the same--ulceration, although the exact cause may vary. The treatment principle involves dressing and avoiding pressure on the ulcerated site called 'offloading' and patient education for prevention. AIM OF THE STUDY: To determine the outcome of non-healing planter ulcers in an anaesthetic foot treated with offloading, total contact casting (TCC), in terms of rate and duration of healing and percentage of ulcers healed based on improvement of Wagner's grading with respect to the clinical profile of the patient...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255059/correlation-between-clinical-tests-and-electroneuromyography-for-the-diagnosis-of-leprosy-neuropathy
#14
Pedro Olavo De Paula Lima, Francisco Marcos Bezerra Cunha, Heitor De Sá Gonçalves, Maria Araci Pontes Aires, Rosa Lívia Freitas De Almeida, Ligia Regina Franco Sansigolo Kerr
BACKGROUND: In leprosy, sensory function of nerves is evaluated with monofilaments test and the motor function with voluntary muscle test, however electroneuromyography is considered as the gold-standard tool. OBJECTIVES: This study aimed: i) to evaluate the correlation between clinical tests and electroneuromyography for the diagnosis of leprosy neuropathy; and ii) to identify the prevalence of leprosy neuropathy and the most compromised peripheral nerves in leprosy...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255058/the-association-between-neuropathic-pain-and-disability-grades-in-leprosy
#15
Rogério Del'Arco, Adrieli Barboza De Oliveira, Susilene Maria Tonelli Nardi, Vânia Del'Arco Paschoal
OBJECTIVE: To detect neuropathic pain in people who have had leprosy and correlate this association with the WHO Degree of Physical Disability classification (DPD-WHO). PATIENTS AND METHODS: Data were collected from medical records, interviews and physical examinations of patients treated in 2013 in a regional referral service that attends 102 municipals. Clinical and general data, the DPD-WHO classification and the Douleur Neuropathique 4 Questionnaire (DN4) were utilised to determine the profile and to diagnose neuropathic pain...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255057/children-and-adolescents-attitude-towards-having-leprosy-in-a-high-endemic-district-of-india
#16
Pitchaimani Govindharaj, Joydeepa Darlong, Annamma S John, Suresh Mani
No abstract text is available yet for this article.
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255056/leprosy-in-brazilian-counties-bordering-paraguay-mato-grosso-do-sul-state-2001-2011
#17
Maria Elizabeth Araújo Ajalla, Sonia Maria Oliveira De Andrade, Edson Mamoru Tamaki, William Waissmann, Sandra Helena Correia Deittrich, Valter Aragão Do Nascimento
BACKGROUND: In Mato Grosso do Sul state, Brazil, the dry border shared with Paraguay is a territory marked by facilities in the flow of goods, services and people, bringing difficulties for surveillance of communicable diseases. PURPOSE: The purpose of this study is to characterise leprosy epidemiologically in dry border municipalities of Mato Grosso do Sul in Brazil with contiguous urban areas with neighbouring Paraguayan counties, in the period 2001-2011. METHODS: This is an exploratory descriptive investigation that includes the four dry border municipalities of Mato Grosso do Sul (Coronel Sapucaia, Paranhos, Ponta Porã, and Sete Quedas) in Brazil whose urban areas are contiguous with Paraguay...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255055/how-to-improve-early-case-detection-in-low-endemic-areas-with-pockets-of-leprosy-a-study-of-newly-detected-leprosy-patients-in-guizhou-province-people-s-republic-of-china
#18
Jinlan Li, Lili Yang, Ying Wang, Hang Liu, Jie Liu, Hugh Cross
Although leprosy in China is controlled at a low endemic level, the number of new cases in Guizhou province has shown no significant decrease over the past 20 years. Guizhou remains the province with the second highest prevalence in China. The authors conducted a study in which the characteristics of newly detected leprosy cases, found between 2008 and 2012 in Guizhou, were analysed. These cases represented people from pocket areas of leprosy in a generally low endemic environment. The purpose of the study was to understand characters of newly detected cases, strong points and weakness of routine detection approaches for improving the effectiveness of early case detection in the future...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/27255054/investment-case-concepts-in-leprosy-elimination-a-systematic-review
#19
REVIEW
Anuj Tiwari, Jan Hendrik Richardus
INTRODUCTION: Leprosy continues to be a global public health problem, but draws less attention because 'prevalence based elimination' has been misinterpreted as eradication. The ongoing transmission of M. leprae has renewed interest in complete elimination. The aim of our study is to review systematically the literature regarding the elimination of leprosy, and to assess this information on its applicability for defining a Leprosy Elimination Investment Case (LEIC) based on Eradication Investment Case guidelines...
March 2016: Leprosy Review
https://www.readbyqxmd.com/read/26964440/erythema-nodosum-leprosum-international-study-group-3rd-enlist-meeting-report-mumbai-7th-9th-april-2015
#20
Steve Walker, Diana Lockwood
No abstract text is available yet for this article.
December 2015: Leprosy Review
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