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Stroke; a Journal of Cerebral Circulation

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https://www.readbyqxmd.com/read/28100765/acute-transient-vestibular-syndrome-prevalence-of-stroke-and-efficacy-of-bedside-evaluation
#1
Jae-Hwan Choi, Min-Gyu Park, Seo Young Choi, Kyung-Pil Park, Seung Kug Baik, Ji-Soo Kim, Kwang-Dong Choi
BACKGROUND AND PURPOSE: The aim of this study was to determine the prevalence of stroke and efficacy of bedside evaluation in diagnosing stroke in acute transient vestibular syndrome (ATVS). METHODS: We performed a prospective, single-center, observational study that had consecutively recruited 86 patients presenting with ATVS to the emergency department of Pusan National University Yangsan Hospital from January to December 2014. All patients received a constructed evaluation, including HINTS plus (head impulse, nystagmus patterns, test of skew, and finger rubbing) and brain magnetic resonance imagings...
January 18, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28100764/drip-n-ship-versus-mothership-for-endovascular-treatment-modeling-the-best-transportation-options-for-optimal-outcomes
#2
Matthew S W Milne, Jessalyn K Holodinsky, Michael D Hill, Anders Nygren, Chao Qiu, Mayank Goyal, Noreen Kamal
BACKGROUND AND PURPOSE: There is uncertainty regarding the best way for patients outside of endovascular-capable or Comprehensive Stroke Centers (CSC) to access endovascular treatment for acute ischemic stroke. The role of the nonendovascular-capable Primary Stroke Centers (PSC) that can offer thrombolysis with alteplase but not endovascular treatment is unclear. A key question is whether average benefit is greater with early thrombolysis at the closest PSC before transportation to the CSC (Drip 'n Ship) or with PSC bypass and direct transport to the CSC (Mothership)...
January 18, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28093531/lifestyle-factors-and-early-clinical-outcome-in-patients-with-acute-stroke-a-population-based-study
#3
Annette Ingeman, Grethe Andersen, Reimar W Thomsen, Heidi H Hundborg, Henrik H Rasmussen, Søren P Johnsen
BACKGROUND AND PURPOSE: We examined the associations of individual and combined lifestyle factors with early adverse stroke outcomes. METHODS: A total of 82 597 patients were identified from nationwide registries. Lifestyle factors at the time of stroke admission included body mass index (kg/m(2)), smoking habits, and alcohol intake, which were grouped (healthy, moderately healthy, moderately unhealthy, and unhealthy). The associations between lifestyle and outcomes were examined using multivariable regression...
January 16, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28087807/field-validation-of-the-los-angeles-motor-scale-as-a-tool-for-paramedic-assessment-of-stroke-severity
#4
Joon-Tae Kim, Pil-Wook Chung, Sidney Starkman, Nerses Sanossian, Samuel J Stratton, Marc Eckstein, Frank D Pratt, Robin Conwit, David S Liebeskind, Latisha Sharma, Lucas Restrepo, May-Kim Tenser, Miguel Valdes-Sueiras, Jeffrey Gornbein, Scott Hamilton, Jeffrey L Saver
BACKGROUND AND PURPOSE: The Los Angeles Motor Scale (LAMS) is a 3-item, 0- to 10-point motor stroke-deficit scale developed for prehospital use. We assessed the convergent, divergent, and predictive validity of the LAMS when performed by paramedics in the field at multiple sites in a large and diverse geographic region. METHODS: We analyzed early assessment and outcome data prospectively gathered in the FAST-MAG trial (Field Administration of Stroke Therapy-Magnesium phase 3) among patients with acute cerebrovascular disease (cerebral ischemia and intracranial hemorrhage) within 2 hours of onset, transported by 315 ambulances to 60 receiving hospitals...
January 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28087806/splenectomy-does-not-improve-long-term-outcome-after-stroke
#5
Dannielle Zierath, Angela Shen, Astiana Stults, Theresa Olmstead, Kyra J Becker
BACKGROUND AND PURPOSE: Immune responses to brain antigens after stroke contribute to poor outcome. We hypothesized that splenectomy would lessen the development of such responses and improve outcome. METHODS: Male Lewis rats (275-350 g) underwent 2-hour middle cerebral artery occlusion immediately after splenectomy or sham splenectomy. Animals were survived to 4 weeks (672 hrs), and immune responses to myelin basic protein determined at euthanasia. Infarct volume was determined in a subset of animals euthanized at 72 hours...
January 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28087805/prehospital-scales-for-large-vessel-occlusion-closing-in-on-a-moving-target
#6
EDITORIAL
Patrik Michel
No abstract text is available yet for this article.
January 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28087804/clinical-selection-strategies-to-identify-ischemic-stroke-patients-with-large-anterior-vessel-occlusion-results-from-sits-istr-safe-implementation-of-thrombolysis-in-stroke-international-stroke-thrombolysis-registry
#7
Jan F Scheitz, Azmil H Abdul-Rahim, Rachael L MacIsaac, Charith Cooray, Heidi Sucharew, Dawn Kleindorfer, Pooja Khatri, Joseph P Broderick, Heinrich J Audebert, Niaz Ahmed, Nils Wahlgren, Matthias Endres, Christian H Nolte, Kennedy R Lees
BACKGROUND AND PURPOSE: The National Institutes of Health Stroke Scale (NIHSS) correlates with presence of large anterior vessel occlusion (LAVO). However, the application of the full NIHSS in the prehospital setting to select patients eligible for treatment with thrombectomy is limited. Therefore, we aimed to evaluate the prognostic value of simple clinical selection strategies. METHODS: Data from the Safe Implementation of Thrombolysis in Stroke International Stroke Thrombolysis Registry (January 2012-May 2014) were analyzed retrospectively...
January 13, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28082671/telemedicine-can-replace-the-neurologist-on-a-mobile-stroke-unit
#8
Tzu-Ching Wu, Stephanie A Parker, Amanda Jagolino, Jose-Miguel Yamal, Ritvij Bowry, Abraham Thomas, Amy Yu, James C Grotta
BACKGROUND AND PURPOSE: The BEST-MSU study (Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit) is a comparative effectiveness trial in patients randomized to mobile stroke unit or standard management. A substudy tested inter-rater agreement for tissue-type plasminogen activator eligibility between a telemedicine vascular neurologist and onboard vascular neurologist. METHODS: On scene, both the telemedicine vascular neurologist and onboard vascular neurologist independently evaluated the patient, documenting their tissue-type plasminogen activator treatment decision, National Institutes of Health Stroke Scale score, and computed tomographic interpretation...
January 12, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28082670/new-insight-into-the-pathogenesis-of-cerebral-small-vessel-diseases
#9
Kristin Müller, Gilles Courtois, Matilde Valeria Ursini, Markus Schwaninger
No abstract text is available yet for this article.
January 12, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28082669/stroke-as-the-initial-manifestation-of-atrial-fibrillation-the-framingham-heart-study
#10
Steven A Lubitz, Xiaoyan Yin, David D McManus, Lu-Chen Weng, Hugo J Aparicio, Allan J Walkey, Jose Rafael Romero, Carlos S Kase, Patrick T Ellinor, Philip A Wolf, Sudha Seshadri, Emelia J Benjamin
BACKGROUND AND PURPOSE: To prevent strokes that may occur as the first manifestation of atrial fibrillation (AF), screening programs have been proposed to identify patients with undiagnosed AF who may be eligible for treatment with anticoagulation. However, the frequency with which patients with AF present with stroke as the initial manifestation of the arrhythmia is unknown. METHODS: We estimated the frequency with which AF may present as a stroke in 1809 community-based Framingham Heart Study participants with first-detected AF and without previous strokes, by tabulating the frequencies of strokes occurring on the same day, within 30 days before, 90 days before, and 365 days before first-detected AF...
January 12, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28082668/be-fast-balance-eyes-face-arm-speech-time-reducing-the-proportion-of-strokes-missed-using-the-fast-mnemonic
#11
Sushanth Aroor, Rajpreet Singh, Larry B Goldstein
BACKGROUND AND PURPOSE: The FAST algorithm (Face, Arm, Speech, Time) helps identify persons having an acute stroke. We determined the proportion of patients with acute ischemic stroke not captured by FAST and evaluated a revised mnemonic. METHODS: Records of all patients admitted to the University of Kentucky Stroke Center between January and December 2014 with a discharge International Classification of Diseases, Ninth Revision, Clinical Modification code for acute ischemic stroke were reviewed...
January 12, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28077455/symptomatic-carotid-occlusion-is-frequently-associated-with-microembolization
#12
Ava L Liberman, Ali Zandieh, Caitlin Loomis, Jonathan M Raser-Schramm, Christina A Wilson, Jose Torres, Koto Ishida, Swaroop Pawar, Rebecca Davis, Michael T Mullen, Steven R Messé, Scott E Kasner, Brett L Cucchiara
BACKGROUND AND PURPOSE: Symptomatic carotid artery disease is associated with significant morbidity and mortality. The pathophysiologic mechanisms of cerebral ischemia among patients with carotid occlusion remain underexplored. METHODS: We conducted a prospective observational cohort study of patients hospitalized within 7 days of ischemic stroke or transient ischemic attack because of ≥50% carotid artery stenosis or occlusion. Transcranial Doppler emboli detection was performed in the middle cerebral artery ipsilateral to the symptomatic carotid...
January 11, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28077454/using-the-national-institutes-of-health-stroke-scale
#13
REVIEW
Patrick Lyden
No abstract text is available yet for this article.
January 11, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28070003/pregnancy-hormonal-treatments-for-infertility-contraception-and-menopause-in-women-after-ischemic-stroke-a-consensus-document
#14
Valeria Caso, Alberto Falorni, Cheryl D Bushnell, Monica Acciarresi, José Remohí, Nikola Sprigg, Sandro Gerli
No abstract text is available yet for this article.
January 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28070002/response-by-jung-et-al-to-letter-regarding-article-takotsubo-like-myocardial-dysfunction-in-ischemic-stroke-a-hospital-based-registry-and-systematic-literature-review
#15
LETTER
Jin-Man Jung, Jung Bin Kim, Woo-Keun Seo
No abstract text is available yet for this article.
January 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28070001/neuroimaging-biomarkers-predict-brain-structural-connectivity-change-in-a-mouse-model-of-vascular-cognitive-impairment
#16
Philipp Boehm-Sturm, Martina Füchtemeier, Marco Foddis, Susanne Mueller, Rebecca C Trueman, Marietta Zille, Jan Leo Rinnenthal, Theodore Kypraios, Laurence Shaw, Ulrich Dirnagl, Tracy D Farr
BACKGROUND AND PURPOSE: Chronic hypoperfusion in the mouse brain has been suggested to mimic aspects of vascular cognitive impairment, such as white matter damage. Although this model has attracted attention, our group has struggled to generate a reliable cognitive and pathological phenotype. This study aimed to identify neuroimaging biomarkers of brain pathology in aged, more severely hypoperfused mice. METHODS: We used magnetic resonance imaging to characterize brain degeneration in mice hypoperfused by refining the surgical procedure to use the smallest reported diameter microcoils (160 μm)...
January 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28070000/anesthesia-technique-and-outcomes-of-mechanical-thrombectomy-in-patients-with-acute-ischemic-stroke
#17
Kimon Bekelis, Symeon Missios, Todd A MacKenzie, Stavropoula Tjoumakaris, Pascal Jabbour
BACKGROUND AND PURPOSE: The impact of anesthesia technique on the outcomes of mechanical thrombectomy for acute ischemic stroke remains an issue of debate. We investigated the association of general anesthesia with outcomes in patients undergoing mechanical thrombectomy for ischemic stroke. METHODS: We performed a cohort study involving patients undergoing mechanical thrombectomy for ischemic stroke from 2009 to 2013, who were registered in the New York Statewide Planning and Research Cooperative System database...
January 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28069999/letter-by-nagai-et-al-regarding-article-takotsubo-like-myocardial-dysfunction-in-ischemic-stroke-a-hospital-based-registry-and-systematic-literature-review
#18
LETTER
Michiaki Nagai, Keigo Dote, Masaya Kato
No abstract text is available yet for this article.
January 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28062861/incidence-locations-and-longitudinal-course-of-cerebral-microbleeds-in-european-moyamoya
#19
Holger Wenz, Ralf Wenz, Máté Maros, Gregory Ehrlich, Mansour Al-Zghloul, Christoph Groden, Alex Förster
BACKGROUND AND PURPOSE: Cerebral microbleeds (cMBs) have previously been linked with especially high incidence in Asian patients with moyamoya together with high tendency to bleed. This, presumably, is characteristic of patients with moyamoya. Herein, we, therefore, investigate retrospectively the frequency, location, and longitudinal course of cMBs in a large German cohort. METHODS: We included all patients with moyamoya who underwent standard magnetic resonance imaging, including T2*-weighted images, in our department between 1998 and 2015...
January 6, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28062860/response-by-sugiyama-and-tominaga-to-letter-regarding-article-blood-flow-into-basilar-tip-aneurysms-a-predictor-for-recanalization-after-coil-embolization
#20
LETTER
Shin-Ichiro Sugiyama, Teiji Tominaga
No abstract text is available yet for this article.
January 6, 2017: Stroke; a Journal of Cerebral Circulation
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