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Contraception

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https://www.readbyqxmd.com/read/28089262/erratum-to-2016-north-american-forum-on-family-planning-scientific-abstracts-denver-co-november-5-7-2016-contraception-94-2016-p-431
#1
(no author information available yet)
No abstract text is available yet for this article.
January 12, 2017: Contraception
https://www.readbyqxmd.com/read/28088498/vaginal-misoprostol-prior-to-intrauterine-device-insertion-in-women-delivered-only-by-elective-cesarean-section-a-randomized-double-blind-clinical-trial
#2
Mohamed S Abdellah, Ahmed M Abbas, Aml M Hegazy, Ihab M El-Nashar
OBJECTIVE: The current study aims to evaluate if vaginal misoprostol (400 mcg) administered prior to intrauterine device (IUD) insertion increase the ease and success of insertion among women who had delivered only by elective Cesarean delivery (CD). STUDY DESIGN: The current study was a randomized, double-blind, placebo-controlled trial, conducted in Assiut Women's Health Hospital, Egypt between the 1st of April 2015 and the 31st of March 2016 included women delivered only by elective CD...
January 11, 2017: Contraception
https://www.readbyqxmd.com/read/28088497/offering-the-full-range-of-contraceptive-options-a-survey-of-interest-in-vasectomy-training-in-the-us-family-planning-community
#3
Brian T Nguyen, Andrea L Jochim, Grace H Shih
OBJECTIVE: To assess current practices regarding female and male sterilization counseling and provision, as well as determine interest in providing vasectomy among family planning specialists. METHODS: Members of the US-based network of family planning fellowship physicians (current fellows, graduates, and faculty) received a web-based survey from November 2015 through January 2016 regarding current sterilization preferences and practices, as well as interest in obtaining training in vasectomy counseling and procedure...
January 11, 2017: Contraception
https://www.readbyqxmd.com/read/28088496/endogenous-thrombin-potential-changes-during-the-first-cycle-of-oral-contraceptive-use
#4
Carolyn L Westhoff, Malcolm C Pike, Serge Cremers, Andrew Eisenberger, Stella Thomassen, Jan Rosing
OBJECTIVES: Venous thromboembolism (VTE) risk increases within months of combination oral contraceptive (COC) initiation. Because elevated endogenous thrombin potential (ETP) has been found in several studies to be a VTE risk factor, we evaluated the extent of ETP changes during the initial cycle of an ethinyl estradiol (EE) and levonorgestrel (LNG) COC. We also assessed the relationship between ETP changes and systemic EE and LNG concentrations. STUDY DESIGN: Participants provided multiple blood samples during a first 21-day cycle of a 30 μg EE/150 μg LNG COC and after a further 7 days without an active COC...
January 11, 2017: Contraception
https://www.readbyqxmd.com/read/28069491/shared-decision-making-in-contraceptive-counseling
#5
Christine Dehlendorf, Kevin Grumbach, Julie A Schmittdiel, Jody Steinauer
BACKGROUND: Shared decision making (SDM) is a potentially valuable but underexplored approach to contraceptive counseling. METHODS: We determined the correlation between patient report of SDM and of whether their provider had a method preference with measures of satisfaction. RESULTS: Women reporting SDM were more likely to be satisfied with counseling than those reporting a provider-driven decision, and were more likely to be satisfied with their method than those reporting a patient-driven decision...
January 6, 2017: Contraception
https://www.readbyqxmd.com/read/28065833/standardizing-abortion-research-outcomes-star-a-protocol-for-developing-disseminating-and-implementing-a-core-outcome-set-for-medical-and-surgical-abortion
#6
Katherine C Whitehouse, Caron R Kim, Bela Ganatra, James M N Duffy, Jennifer Blum, Dalia Brahmi, Mitchell D Creinin, Teresa DePiñeres, Kristina Gemzell-Danielsson, Daniel Grossman, Beverly Winikoff, A Metin Gülmezoglu
BACKGROUND: Abortion is one of the most common events in women's healthcare worldwide. Currently there is no standardization for the selection and reporting of outcomes in abortion clinical trials. This heterogeneity in clinical trials can make it difficult to draw meaningful conclusions across studies. OBJECTIVE: We aim to develop, disseminate, and implement a core outcome set (COS) for medical and surgical abortion trials. MATERIALS & METHODS: To guide this project, we have assembled a local study management team and an international advisory group including abortion providers, researchers, methodologists, and abortion clients...
January 5, 2017: Contraception
https://www.readbyqxmd.com/read/28063830/implications-of-dispensing-self-administered-hormonal-contraceptives-in-a-one-year-supply-a-california-case-study
#7
Sara B McMenamin, Shana Alex Charles, Nadia Tabatabaeepour, Erin Shigekawa, Garen Corbett
On September 23, 2016, California became the 6th state to pass legislation requiring health plans and insurers to cover a 12-month supply of FDA-approved self-administered hormonal contraceptives such as contraceptive pills, patches, and vaginal rings. This legislation is estimated to result in 47% of current contraceptive pill, patch, and ring users receiving a 12-month supply dispensed at one time. This shift in dispensing patterns was estimated to result in a reduction of 15,000 unintended pregnancies; 2000 fewer miscarriages; and 7000 fewer abortions in California decreasing total net health care expenditures by 0...
January 4, 2017: Contraception
https://www.readbyqxmd.com/read/28041992/changes-in-body-composition-in-women-using-long-acting-reversible-contraception
#8
Priscilla de Nazaré Silva Dos Santos, Tessa Madden, Karen Omvig, Jeffrey F Peipert
OBJECTIVE: Users of hormonal long-acting reversible contraception (LARC) report weight gain as a side effect, but few studies have assessed body composition change among LARC users. We evaluated weight and body composition of healthy women using the levonorgestrel intrauterine system (LNG-IUS), copper intrauterine device (copper IUD) or etonogestrel implant (ENG implant). We hypothesized that weight gain and body composition over 12 months would not differ between copper IUD, LNG-IUS and ENG implant users...
December 30, 2016: Contraception
https://www.readbyqxmd.com/read/28041991/serial-multilevel-urine-pregnancy-testing-to-assess-medical-abortion-outcome-a-meta-analysis
#9
Elizabeth G Raymond, Tara Shochet, Jennifer Blum, Wendy R Sheldon, Ingrida Platais, Hillary Bracken, Rasha Dabash, Mark A Weaver, Nguyen Thi Nhu Ngoc, Paul D Blumenthal, Beverly Winikoff
OBJECTIVES: To summarize data on the accuracy of a strategy designed to exclude ongoing pregnancy after medical abortion treatment by observing a decline in urine human chorionic gonadotropin (hCG) concentration as estimated by multilevel urine pregnancy tests (MLPTs) performed before and after treatment. STUDY DESIGN: We collated original data from seven studies performed by our organization that evaluated the accuracy of the MLPT strategy for assessment of outcome of medical abortion...
December 29, 2016: Contraception
https://www.readbyqxmd.com/read/28041990/estimating-systemic-exposure-to-levonorgestrel-from-an-oral-contraceptive
#10
Cale N Basaraba, Carolyn L Westhoff, Malcolm C Pike, Renu Nandakumar, Serge Cremers
OBJECTIVE: The gold standard for measuring oral contraceptive (OC) pharmacokinetics is the 24-h steady-state area-under-the-curve (AUC). We conducted this study to assess whether limited sampling at steady state or measurements following use of one or two OCs could provide an adequate proxy in epidemiological studies for the progestin 24-h steady-state AUC of a particular OC. STUDY DESIGN: We conducted a 13-sample, 24-h pharmacokinetic study on both day 1 and day 21 of the first cycle of a monophasic OC containing 30 μg ethinyl estradiol and 150 μg levonorgestrel (LNG) in 17 normal-weight healthy white women, and a single-dose 9-sample study of the same OC after a one-month washout...
December 29, 2016: Contraception
https://www.readbyqxmd.com/read/28038949/could-misreporting-of-condom-use-explain-the-observed-association-between-injectable-hormonal-contraceptives-and-hiv-acquisition-risk
#11
Jennifer A Smith, Renee Heffron, Ailsa R Butler, Connie Celum, Jared M Baeten, Timothy B Hallett
OBJECTIVE: Some observational studies have suggested an association between the use of hormonal contraceptives (HC) and HIV acquisition. One major concern is that differential misreporting of sexual behaviour between HC users and non-users may generate artificially inflated risk estimates. STUDY DESIGN: We developed an individual-based model that simulates the South African HIV serodiscordant couples analysed for HC-HIV risk by Heffron et al. (2012). We varied the pattern of misreporting condom use between HC users and non-users and reproduced the trial data under the assumption that HC use is not associated with HIV risk...
December 27, 2016: Contraception
https://www.readbyqxmd.com/read/28025018/pharmacy-provision-of-sexual-and-reproductive-health-commodities-to-young-people-a-systematic-literature-review-and-synthesis-of-the-evidence
#12
REVIEW
Lianne Gonsalves, Michelle J Hindin
BACKGROUND: We conducted a systematic review of peer-reviewed literature on youth access to, use of and quality of care of sexual and reproductive health (SRH) commodities through pharmacies. METHODS: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, we searched for publications from 2000 to 2016. To be eligible for inclusion, articles had to address the experiences of young people (aged 25 years and below) accessing SRH commodities (e...
December 23, 2016: Contraception
https://www.readbyqxmd.com/read/28011288/pooled-analysis-of-two-randomized-open-label-studies-comparing-the-effects-of-nomegestrol-acetate-17%C3%AE-estradiol-and-drospirenone-ethinyl-estradiol-on-bleeding-patterns-in-healthy-women
#13
Diana Mansour, Carolyn Westhoff, Uma Kher, Tjeerd Korver
OBJECTIVES: To obtain more precise and detailed information regarding the bleeding patterns of nomegestrol acetate (NOMAC)/17β-estradiol (E2) and drospirenone/ethinyl estradiol (DRSP/EE) and to identify whether baseline demographic characteristics were associated with unscheduled bleeding, absent scheduled bleeding, or amenorrhea. STUDY DESIGN: This analysis pooled results from two pivotal open-label, randomized trials that compared bleeding patterns of NOMAC/E2 and DRSP/EE...
December 20, 2016: Contraception
https://www.readbyqxmd.com/read/27940059/use-of-the-levonorgestrel-52-mg-intrauterine-system-in-adolescent-and-young-adult-solid-organ-transplant-recipients-a-case-series
#14
P S Huguelet, C Sheehan, R F Spitzer, S Scott
This case series reports on the safety and efficacy of the levonorgestrel 52-mg intrauterine system in adolescent and young adult solid organ transplant recipients. All patients used the device for contraception, with no documented cases of disseminated pelvic infection or unplanned pregnancy.
December 7, 2016: Contraception
https://www.readbyqxmd.com/read/27913231/immediate-postpartum-long-acting-reversible-contraception-the-time-is-now
#15
Michelle Moniz, Tammy Chang, Michele Heisler, Vanessa K Dalton
No abstract text is available yet for this article.
November 29, 2016: Contraception
https://www.readbyqxmd.com/read/27913230/effects-of-combined-oral-contraceptives-depot-medroxyprogesterone-acetate-and-the-levonorgestrel-releasing-intrauterine-system-on-the-vaginal-microbiome
#16
J Paul Brooks, David J Edwards, Diana L Blithe, Jennifer M Fettweis, Myrna G Serrano, Nihar U Sheth, Jerome F Strauss, Gregory A Buck, Kimberly K Jefferson
OBJECTIVES: Prior studies suggest that the composition of the vaginal microbiome may positively or negatively affect susceptibility to sexually transmitted infections (STIs) and bacterial vaginosis (BV). Some female hormonal contraceptive methods also appear to positively or negatively influence STI transmission and BV. Therefore, changes in the vaginal microbiome that are associated with different contraceptive methods may explain, in part, effects on STI transmission and BV. STUDY DESIGN: We performed a retrospective study of 16S rRNA gene survey data of vaginal samples from a subset of participants from the Human Vaginal Microbiome Project at Virginia Commonwealth University...
November 29, 2016: Contraception
https://www.readbyqxmd.com/read/27913229/a-single-arm-phase-iii-study-exploring-the-efficacy-and-safety-of-lng-ius-8-a-low-dose-levonorgestrel-intrauterine-contraceptive-system-total-content-13-5-mg-in-an-asia-pacific-population
#17
Guangsheng Fan, Sukho Kang, Mulan Ren, Edith Weisberg, Eeva Lukkari-Lax, Katrin Roth, SoYoung Shin
OBJECTIVE: The objective was to evaluate the efficacy and safety of a low-dose levonorgestrel intrauterine system with total content 13.5 mg (average approximately 8 μg/24 h over the first year; LNG-IUS 8; Jaydess®) in an Asia-Pacific population. STUDY DESIGN: An open-label, single-arm phase III study conducted at 25 centers in China, Australia and Korea assessed LNG-IUS 8 use over 3 years in nulliparous and parous women (N=1114) aged 18-40 years with regular menstrual cycles (21-35 days)...
November 29, 2016: Contraception
https://www.readbyqxmd.com/read/27888047/looking-for-a-lost-subdermal-contraceptive-implant-think-about-the-pulmonary-artery
#18
A Gallon, M Fontarensky, C Chauffour, L Boyer, P Chabrot
This case highlights a rare but potentially life-threatening complication of a contraceptive implant insertion that was corrected by a noninvasive endovascular procedure. This procedure requires a quick intervention to be successful.
November 22, 2016: Contraception
https://www.readbyqxmd.com/read/27888046/proposed-clinical-guidance-for-excluding-pregnancy-prior-to-contraceptive-initiation
#19
John Stanback, Irina Yacobson, Lucy Harber
No abstract text is available yet for this article.
November 22, 2016: Contraception
https://www.readbyqxmd.com/read/27865875/axillary-migration-of-nexplanon%C3%A2-case-report
#20
Daniela Diego, Erryn Tappy, Jose Carugno
A 19-year-old patient presented to the clinic, and we inserted a single rod subdermal etonogestrel implant (Nexplanon ®), which subsequently migrated to the ipsilateral axilla. Distant Nexplanon® migration is a rare serious complication that should be considered when a device is nonpalpable. Management options are discussed.
November 16, 2016: Contraception
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