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Postgraduate Medical Journal

Claire Kelly, Marinos Pericleous
Wilson disease is a rare but important disorder of copper metabolism, with a failure to excrete copper appropriately into bile. It is a multisystem condition with presentations across all branches of medicine. Diagnosis can be difficult and requires a high index of suspicion. It should be considered in unexplained liver disease particularly where neuropsychiatric features are also present. Treatments are available for all stages of disease. A particularly important presentation not to overlook is acute liver failure which carries a high mortality risk and may require urgent liver transplantation...
February 15, 2018: Postgraduate Medical Journal
Tsuneaki Kenzaka, Moe Kyotani, Ken Goda, Hozuka Akita
No abstract text is available yet for this article.
February 12, 2018: Postgraduate Medical Journal
Trevor William Lambert, Fay Smith, Michael J Goldacre
OBJECTIVE: To report the career specialty choices of UK medical graduates of 2015 one year after graduation and to compare these with the choices made at the same postgraduate stage by previous cohorts. DESIGN: National survey using online and postal questionnaires. SETTING: UK. PARTICIPANTS: UK-trained medical graduates. MAIN OUTCOME MEASURES: Grouped and individual specialty choices. RESULTS: The response rate was 41...
February 12, 2018: Postgraduate Medical Journal
Nainesha Kulkarni, Abhishek Chitnis
No abstract text is available yet for this article.
February 12, 2018: Postgraduate Medical Journal
Jithma P Abeykoon, Jonas Paludo, Mark Enzler
No abstract text is available yet for this article.
February 9, 2018: Postgraduate Medical Journal
Marta Waliszewska-Prosół, Krystian Obara, Paweł Szewczyk, Małgorzata Śniatowska, Sławomir Budrewicz
No abstract text is available yet for this article.
February 6, 2018: Postgraduate Medical Journal
Vassili Crispi, Antonios Matsakas
Duchenne muscular dystrophy (DMD) is a progressive wasting disease of skeletal and cardiac muscles, representing one of the most common recessive fatal inherited genetic diseases with 1:3500-1:5000 in yearly incidence. It is caused by mutations in the DMD gene that encodes the membrane-associated dystrophin protein. Over the years, many have been the approaches to management of DMD, but despite all efforts, no effective treatment has yet been discovered. Hope for the development of potential therapeutics has followed the recent advances in genome editing and gene therapy...
January 31, 2018: Postgraduate Medical Journal
Guramrinder Singh Thind, Steve Zanders, Joanne K Baker
Elucidation of the structural basis of endothelial barrier function and the study of transcapillary fluid exchange dynamics are areas of active research. There has been significant enhancement in our understanding of the ultrastructural basis of endothelial barrier function. The role of glycocalyx has received special attention. Experimental evidence has called for a revision in the classic Starling principle of transcapillary exchange. The glycocalyx model provides a potential structural mechanism for the revised Starling principle...
January 26, 2018: Postgraduate Medical Journal
Jeremy Neale, James Cameron Spence, Ajay Varghese
No abstract text is available yet for this article.
January 20, 2018: Postgraduate Medical Journal
Muhammad U Dogar, Niel N Shah, Sameera Ishtiaq, Parin N Shah, Pratik Shah, Shawn Mathew, Timothy J Vittorio
No abstract text is available yet for this article.
January 20, 2018: Postgraduate Medical Journal
Omar Viswanath, Musa Aner
No abstract text is available yet for this article.
January 17, 2018: Postgraduate Medical Journal
Peter Gillen, Sue Faye Sharifuddin, Muireann O'Sullivan, Alison Gordon, Eva M Doherty
BACKGROUND: This explorative study was triggered by the '#hellomynameis' campaign initiated by Dr Kate Granger in the UK. Our objectives were twofold: first, to measure rates of introduction in an Irish hospital setting by both consultant and non-consultant hospital doctors. Second to establish whether such practices were associated with patient perceptions of the doctor/patient interaction. METHOD: A patient 'exit' survey was undertaken following doctor-patient consultations in both acute (surgical and medical assessment units) and elective settings (outpatient clinics)...
January 13, 2018: Postgraduate Medical Journal
Zahid B Asghar, Aloysius Niroshan Siriwardena, Chris Elfes, Jo Richardson, James Larcombe, Katherine A Neden, Amer Salim, David Smalley, Carol Blow
PURPOSE OF THE STUDY: The aim of this study was to compare performance of candidates who declared an expert-confirmed diagnosis of dyslexia with all other candidates in the Applied Knowledge Test (AKT) of the Membership of the Royal College of General Practitioners licensing examination. STUDY DESIGN: We used routinely collected data from candidates who took the AKT on one or more occasions between 2010 and 2015. Multivariate logistic regression was used to analyse performance of candidates who declared dyslexia with all other candidates, adjusting for candidate characteristics known to be associated with examination success including age, sex, ethnicity, country of primary medical qualification, stage of training, number of attempts and time spent completing the test...
January 12, 2018: Postgraduate Medical Journal
John Kinnear, Nick Wilson, Anthony O'Dwyer
BACKGROUND: The complexity of modern clinical practice has highlighted the fallibility of individual clinicians' decision-making, with effective teamwork emerging as a key to patient safety. Dual process theory is widely accepted as a framework for individual decision-making, with type 1 processes responsible for fast, intuitive and automatic decisions and type 2 processes for slow, analytical decisions. However, dual process theory does not explain cognition at the group level, when individuals act in teams...
January 9, 2018: Postgraduate Medical Journal
Piotr Szawarski, David Hillebrandt
The evolution in communication and digital technologies is revolutionising the practice of medicine. A physician is now able to oversee provision of healthcare at a distance. In this paper, we argue that practice of telemedicine is an essential and evolving aspect of high altitude and expedition medicine. We acknowledge the lack of international consensus, limited legislation as well as possible reservations towards telemedical practice. Given some unique social and medical aspects of participation in remote, high altitude expeditions we propose a number of guiding principles for those involved in provision of telemedical services for such endeavours...
December 20, 2017: Postgraduate Medical Journal
Eugene D'Souza, Catherine Krejany, Rosie Meng, Moyez Jiwa
PURPOSE: To conduct a video vignette survey of medical students and doctors investigating test ordering for patients presenting with self-limiting or minor illness. METHODS: Participants were shown six video vignettes of common self-limiting illnesses and invited to devise investigation and management plans for the patients' current presentation. The number of tests ordered was compared with those recommended by an expert panel. A Theory of Planned Behaviour Questionnaire explored participants' beliefs and attitudes about ordering tests in the context of self-limiting illness...
December 8, 2017: Postgraduate Medical Journal
Chris Brown, Tarig Abdelrahman, Charlotte Thomas, John Pollitt, Wyn G Lewis
INTRODUCTION: Proof of professional specific academic attainment is embedded within the Joint Committee on Surgical Training 2013 general surgery curriculum, mandating that all higher general surgical trainees (HST) obtain three peer-reviewed publications to qualify for Certification of Completion of Training. Yet, Modernising Medical Careers (MMC) has been associated with a trend away from the gold standard postgraduate credentials of higher degrees by research. This study aimed to evaluate the academic achievements of a post-MMC UK Deanery HST cohort to determine what additional benefits higher degree study might confer...
November 29, 2017: Postgraduate Medical Journal
John Launer
No abstract text is available yet for this article.
February 2018: Postgraduate Medical Journal
(no author information available yet)
No abstract text is available yet for this article.
February 2018: Postgraduate Medical Journal
Omar M Chehab, Habib A Dakik
Tobacco smoking contributes to about six million deaths per year and is predicted to increase in the future. Several pharmacological interventions are used for smoking cessation. Trials using nicotine replacement therapy (NRT) in acute coronary syndrome (ACS) showed inconclusive results. Furthermore, three trials using bupropion in patients admitted with ACS failed to show improvement in smoking cessation compared with placebo. Interestingly, only one trial using varenicline was successful in achieving smoking abstinence in the acute setting...
February 2018: Postgraduate Medical Journal
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