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Postgraduate Medical Journal

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https://www.readbyqxmd.com/read/30341231/pharmacological-interventions-for-non-alcoholic-fatty-liver-disease-a-systematic-review-and-network-meta-analysis
#1
Kannan Sridharan, Gowri Sivaramakrishnan, Reginald Paul Sequeira, Abdelaziz Elamin
AIM: Several drugs have been used for treating non-alcoholic fatty liver disease (NAFLD). The present study is a network meta-analysis of such drugs. DESIGN, SETTING AND PATIENTS: Randomised clinical trials comparing drug interventions in patients with NAFLD were analysed. OR and weighted mean difference (95 % CI) were the effect estimates for categorical and numerical outcomes, respectively. Random-effects model was used to generate pooled estimates. Surface under the cumulative ranking curve was used to rank the treatments...
October 19, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30341230/association-between-serum-amyloid-a-levels-and-cancers-a-systematic-review-and-meta-analysis
#2
Jielin Zhou, Jie Sheng, Yong Fan, Xingmeng Zhu, Qi Tao, Yue He, Sufang Wang
OBJECTIVE: Increased serum amyloid A (SAA) levels have been investigated in various human malignancies, but a consistent perspective has not been established to date. This study systematically reviewed the association between SAA levels and cancers. METHODS: Cochrane Library, PubMed and Embase were carefully searched for available studies. The following keywords were used in database searches: 'serum amyloid A', 'SAA', 'cancer', 'tumour', 'carcinoma', 'nubble', 'knurl' and 'lump'...
October 19, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30341229/expression-of-death-receptor-3-dr3-on-peripheral-blood-mononuclear-cells-of-patients-with-psoriasis-vulgaris
#3
Lin Li, Yonghong Lu, Lixin Fu, Peimei Zhou, Liwen Zhang, Wenju Wang, Jianjun Nie, Dawei Zhang, Yan Liu, Bo Wu, Yi Zhou, Tao Chen
BACKGROUND: A series of previous reports indicated that tumour necrosis factor-like ligand 1A (TL1A) and its receptor death receptor 3 (DR3) are involved in the pathogenesis of psoriasis vulgaris (PV), which is a common chronic skin disease accompanied by a number of comorbidities, although their exact roles remain unclear. Our previous studies demonstrated that serum TL1A levels were substantially elevated in patients with PV, but the detection of DR3 expression in peripheral blood mononuclear cells (PBMCs) of patients with PV had not been reported...
October 19, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30341228/wrist-drop-and-focal-seizures-in-a-60-year-old-man
#4
Mehtab Alam, Ayaz Ul Haq
No abstract text is available yet for this article.
October 19, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30333134/diagnostic-efficacy-of-long-non-coding-rna-in-lung-cancer-a-systematic-review-and-meta-analysis
#5
Shui-Ping Dai, Jing Jin, Wei-Min Li
The detection of long non-coding RNA (lncRNA) is a novel method for lung cancer diagnosis. However, the diagnostic efficacy of lncRNA in different studies is inconsistent. Therefore, we conducted this meta-analysis to elucidate the diagnostic efficacy of lncRNA in identification of lung cancer including small cell lung cancer. The online PubMed, Medline, EMBASE, CNKI and Wanfang literature databases were searched to identify all related articles about the diagnostic efficacy of lncRNA for lung cancer. 28 articles including 3044 patients with lung cancer and 2598 controls were enrolled in our meta-analysis...
October 17, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30322951/association-between-cytokine-gene-polymorphisms-and-ankylosing-spondylitis-susceptibility-a-systematic-review-and-meta-analysis
#6
Yi Xia, Yan Liang, Shi Guo, Jie-Gen Yu, Meng-Sha Tang, Peng-Hui Xu, Fen-Dui Qin, Guo-Pin Wang
PURPOSE OF THE STUDY: The aim of this study was to perform a meta-analysis to derive precise estimation of the association of interleukin-23 receptor (IL-23R), IL-1 receptor 2 (IL-1R2), IL-12 beta (IL-12B), IL-10 and tumour necrosis factor (TNF)-α polymorphisms with ankylosing spondylitis (AS) susceptibility. STUDY DESIGN: A systematic literature search was conducted to identify the relevant studies. Pooled OR with 95% CI was calculated to assess the strength of the association in a fixed or random-effects model...
October 15, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30317183/teneligliptin-associated-bullous-pemphigoid-in-an-elderly-man-with-diabetes
#7
Ankur Guliani, Anuradha Bishnoi, Divya Aggarwal, Davinder Parsad
No abstract text is available yet for this article.
October 13, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30317182/breakthrough-cancer-pain-tailored-treatment-which-factors-influence-the-medication-choice-an-observational-prospective-and-cross-sectional-study-in-patients-with-terminal-cancer
#8
Caterina Magnani, Diana Giannarelli, Alice Calvieri, Ana Dardeli, Giovanni Eusepi, Maria Rosa Restuccia, Chiara Mastroianni, Giuseppe Casale
BACKGROUND: Various options for the pharmacological treatment of breakthrough cancer pain (BTcP) are available. International guidelines on BTcP treatment are not univocal. A tailored treatment should be based on the assessment of different variables such as BTcP characteristics, oral mucositis, chronic rhinitis and a patient's ability to take medication. OBJECTIVE: The goal of this study is to assess the relationship between these variables and the medication treatment for BTcP in a sample of patients with terminal cancer...
October 13, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30301836/how-to-pass-the-part-1-frcophth-in-foundation-training
#9
Peng Yong Sim
No abstract text is available yet for this article.
October 9, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30301835/a-long-wait-barriers-to-discharge-for-long-length-of-stay-patients
#10
Emma Jane Zhao, Apurva Yeluru, Lakshman Manjunath, Lei Ray Zhong, Hsiao-Tieh Hsu, Charles K Lee, Anny C Wong, Matthew Abramian, Haley Manella, David Svec, Lisa Shieh
INTRODUCTION: Reducing long length of stay (LLOS, or inpatient stays lasting over 30 days) is an important way for hospitals to improve cost efficiency, bed availability and health outcomes. Discharge delays can cost hundreds to thousands of dollars per patient, and LLOS represents a burden on bed availability for other potential patients. However, most research studies investigating discharge barriers are not LLOS-specific. Of those that do, nearly all are limited by further patient subpopulation focus or small sample size...
October 9, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30301834/red-cell-distribution-width-in-coronary-heart-disease-prediction-of-restenosis-and-its-relationship-with-inflammatory-markers-and-lipids
#11
Hang Qian, Zhihuan Luo, Chunmei Xiao, Jishun Chen, Dongfeng Li, Hao Xu, Peigen He, Xintao Zhou, Tao Zhang, Xinwen Min
BACKGROUND: Red cell distribution width (RDW) is associated with a poor prognosis and adverse events in cardiovascular diseases. The aims of this study were to investigate the relationship between serum RDW levels and outcomes after percutaneous coronary intervention and to identify potential novel laboratory markers for evaluating the risk of in-stent restenosis (ISR) with stable angina pectoris. METHODS: A total of 261 patients with coronary heart disease from Dongfeng General Hospital implanted with a coronary drug-eluting stent (DES) were enrolled in the study...
October 9, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30301833/unilateral-rhinorrhoea-associated-with-cerebrospinal-fluid-leak
#12
Petros Koltsidopoulos, Charalampos Skoulakis, Eleni Papageorgiou
No abstract text is available yet for this article.
October 9, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30282781/microscopic-polyangiitis-after-streptococcal-pharyngitis-in-a-young-woman
#13
Nikolaos Spernovasilis, Kostas Stylianou, Athanasia Milioni, Simeon Panagiotakis
No abstract text is available yet for this article.
October 3, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30282780/warfarin-induced-unilateral-facial-swelling-and-skin-rash
#14
Timothy R Hudd, Pirneeka Chugh, Kathy Zaiken, Nathan W Samuels, Judy Cheng
No abstract text is available yet for this article.
October 3, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30282779/student-led-service-evaluation-of-doctor-introductions-to-patients
#15
Thomas W Grother, David J Wilson
No abstract text is available yet for this article.
October 3, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30232151/impact-of-radiology-reports-on-timely-tuberculosis-diagnosis
#16
Kristen V Dicks, David P Holland, Myra G Allen, Ellen R Fortenberry, Julie Luffman, Elizabeth Zeringue, Jennifer Wheeler, Jason E Stout
PURPOSE: As tuberculosis becomes less common in higher income countries, clinician familiarity with the disease is declining. Little is known about how chest radiograph interpretations affect tuberculosis care. We sought to determine how tuberculosis-related terminology in an initial chest radiograph reading impacted patient care. STUDY DESIGN: We examined a retrospective cohort of patients with pulmonary tuberculosis in North Carolina from 1 January 2011 to 31 December 2014...
September 19, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30224351/severe-hand-foot-skin-reaction-and-erythema-multiforme-like-lesions-due-to-sorafenib
#17
Ankur Guliani, Manju Daroach, Divya Aggarwal, Bishan Dass Radotra, Muthu Sendhil Kumaran
No abstract text is available yet for this article.
September 17, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30209180/learning-curves-in-surgery-variables-analysis-and-applications
#18
Epaminondas Markos Valsamis, Tarak Chouari, Christopher O'Dowd-Booth, Benedict Rogers, David Ricketts
Learning curves graphically represent the relationship between learning effort and learning outcome. Learning curves are increasingly used in research, the design of randomised controlled trials, the assessment of competency, healthcare education and training programme design. In this review we have outlined the principles behind plotting learning curves, described the common methods used to analyse learning curves, how to interpret learning curves, the multitude of learning models, their applications and potential pitfalls, and the importance of a mathematically rigorous approach to learning curve analytics...
September 12, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30196264/intractable-vomiting-and-the-medulla-neuromyelitis-optica-spectrum-disorder-presenting-as-area-postrema-syndrome
#19
Ami Schattner, Arnon Karni
No abstract text is available yet for this article.
September 8, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/30181163/factors-influencing-burn-out-among-resident-physicians-and-the-solutions-they-recommend
#20
Mohd Nasir Bin Mohd Ismail, Sarah Lindstrom Johnson, Sallie J Weaver, Albert W Wu, Andrea C Gielen
No abstract text is available yet for this article.
September 4, 2018: Postgraduate Medical Journal
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