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Dental Clinics of North America

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https://www.readbyqxmd.com/read/29126498/oral-cancer
#1
EDITORIAL
Eric T Stoopler, Thomas P Sollecito
No abstract text is available yet for this article.
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126497/radiation-therapy-for-oral-cavity-and-oropharyngeal-cancers
#2
REVIEW
Alexander Lin
Radiotherapy is a key therapeutic modality used in the treatment of oral cavity and oropharyngeal cancers, whether as definitive treatment or postoperatively for those with high-risk factors after surgery. Although radiotherapy is a proven, effective treatment of cancer control, it can result in significant acute and late toxicities. Pretreatment patient education, supportive care, and posttreatment adherence to rehabilitative and preventive care can help mitigate toxicities. Advances in radiation delivery, such as through continued technological advances, or novel approaches to customizing radiation dose and volume, to maximize the therapeutic efficacy while minimizing side effects, are warranted...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126496/chemotherapy-for-oral-cancer
#3
REVIEW
Lee Hartner
The use of chemotherapy, including immunotherapy, in oral squamous cell carcinoma has expanded considerably in the past several years. Its use mirrors that in the treatment of squamous cell carcinoma affecting other structures in the head and neck. This article summarizes the current evidence that guides use of chemotherapy both in combination with radiation and as monotherapy for patients with advanced disease. It also addresses the expanding role of immunotherapy, particularly use of programmed cell death-ligand 1 inhibitors, in the treatment of advanced disease...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126495/surgical-management-of-oral-cancer
#4
REVIEW
Rabie M Shanti, Bert W O'Malley
Today, most head and neck cancer subsites, such as the larynx, hypopharynx, nasopharynx, and oropharynx, are treated with radiation therapy with or without chemotherapy as a primary treatment modality. Surgery is reserved for the salvage of recurrent tumors that occur within the head and neck in the absence of distant (ie, lung, liver) metastasis. However, unlike all other head and neck subsites, oral cancer should ideally be managed with primary surgery with the possibility of adjuvant radiation therapy with or without chemotherapy depending on the presence of certain high-risk pathologic features...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126494/adjunctive-diagnostic-techniques-for-oral-and-oropharyngeal-cancer-discovery
#5
REVIEW
Michaell A Huber
The most important prognostic factor in predicting the outcome of oral and oropharyngeal cancer (OPC) is the stage at which it is diagnosed. Only 30% of patients are diagnosed with early-stage disease. The oral health care provider performs an important role in early diagnosis of oral cancer. The conventional oral examination consists of a visual and tactile assessment of accessible oral, and head and neck structures. Any suspicious or equivocal lesion should be reevaluated within 4 weeks. Evidence supporting the use of adjunctive devices to improve the ability to screen for and identify OPCs and oral premalignant lesions remains low...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126493/evaluation-and-staging-of-oral-cancer
#6
REVIEW
Mel Mupparapu, Rabie M Shanti
Although the American Joint Committee on Cancer developed its first cancer-specific staging system in 1959, the TNM classification, as it has become known, has undergone many revisions mainly due to the advancements in both diagnosis and management of cancer, Although the basic purpose of the cancer staging system has remained fundamentally unchanged, the ease with which the cancer can be staged has evolved with newer methods. This article reviews cancer evaluation for staging, as well as the introduction of a new staging method effective as of 2018...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126492/oral-cancer-genetics-and-the-role-of-precision-medicine
#7
REVIEW
Chia-Cheng Li, Zhen Shen, Roxanne Bavarian, Fan Yang, Aditi Bhattacharya
Oral squamous cell carcinoma (OSCC) is one of the leading cancers in the world. OSCC patients are managed with surgery and/or chemoradiation. Prognoses and survival rates are dismal, however, and have not improved for more than 20 years. Recently, the concept of precision medicine was introduced, and the introduction of targeted therapeutics demonstrated promising outcomes. This article reviews the current understanding of initiation, progression, and metastasis of OSCC from both genetic and epigenetic perspectives...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126491/impact-of-oral-cancer-on-quality-of-life
#8
REVIEW
Jesus Amadeo Valdez, Michael T Brennan
The clinical manifestations of oral cancer and the effects of treatment can have a negative impact on a patient's quality of life. Physiologic functions, cosmetic appearance, and psychological well-being can become compromised during the diagnosis, treatment, and survivorship of patients with oral cancer. This article addresses the relationship of oral cancer and quality of life, as well as the different aspects affected by this condition.
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126490/dental-management-of-patients-who-have-undergone-oral-cancer-therapy
#9
REVIEW
Alessandro Villa, Sunday O Akintoye
Oral cancer therapies are associated with orofacial complications that could result in dose-limiting cancer treatment and consequent suboptimal tumor control. Oral cancer treatment complications include oral mucositis, salivary gland hypofunction, odontogenic infections, pain, dermatitis, neurotoxicity, soft tissue fibrosis, trismus, osteoradionecrosis, and potential cancer recurrence. These complications significantly affect cancer survivorship, quality of life, and psychosocial status. Effective dental management of patients with oral cancer involves the coordination of care among several health care professionals before, during, and after cancer therapy...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126489/dental-treatment-planning-for-the-patient-with-oral-cancer
#10
REVIEW
Lauren E Levi, Rajesh V Lalla
Oral cancer therapy is associated with a multitude of head and neck sequelae that includes, but is not limited to, hyposalivation, increased risk for dental caries, osteoradionecrosis of the jaw, radiation fibrosis syndrome, mucositis, chemotherapy-induced neuropathy, dysgeusia, dysphagia, mucosal lesions, trismus, and infections. Preparing a comprehensive treatment plan for patients undergoing cancer therapy is essential to help minimize their risks for developing these oral and dental complications. In addition, dentists must take into account a patient's ongoing oncologic therapy for those patients who present to the dentist while concurrently receiving cancer treatment...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126488/human-papillomavirus-and-oropharyngeal-cancer
#11
REVIEW
Takako Imai Tanaka, Faizan Alawi
Human papillomavirus-associated oropharyngeal squamous cell carcinoma (HPV-OPSCC) comprises approximately 25% of all head and neck cancers (head and neck squamous cell carcinoma, HNSCC). Epidemiologic studies have shown a dramatic increase of HPV-OPSCC in the past 2 decades, whereas tobacco-related HNSCC rates are decreasing worldwide. The distinctions between HPV-OPSCC and oral cavity cancers are now reflected in the most recent editions of the World Health Organization Classification of Tumors of the Head and Neck and the American Joint Committee on Cancer Staging Manual, respectively...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29126487/evaluation-and-management-of-oral-potentially-malignant-disorders
#12
REVIEW
Christine Nadeau, Alexander Ross Kerr
Oral potentially malignant disorders (OPMDs) refer to epithelial lesions and conditions with an increased risk for malignant transformation; oral leukoplakia is the most commonly encountered. Overall, OPMDs have a low risk for malignant transformation, yet the challenge is the difficulty to reliably identify and predict which patients with OPMDs are at the highest risk for malignant transformation. Future research is needed to elucidate the molecular aspects of OPMDs, to improve current diagnostic strategies, leading to personalized management...
January 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886773/biomaterials-for-oral-health
#13
EDITORIAL
Jack L Ferracane, Carmem S Pfeifer, Luiz E Bertassoni
No abstract text is available yet for this article.
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886772/dental-implants
#14
REVIEW
Jason A Griggs
Systematic reviews of literature over the period between 2008 and 2017 are discussed regarding clinical evidence for the factors affecting survival and failure of dental implants. The factors addressed include publication bias, tooth location, insertion torque, collar design, implant-abutment connection design, implant length, implant width, bone augmentation, platform switching, surface roughness, implant coatings, and the use of ceramic materials in the implant body and abutment.
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886771/biomaterials-for-craniofacial-bone-regeneration
#15
REVIEW
Greeshma Thrivikraman, Avathamsa Athirasala, Chelsea Twohig, Sunil Kumar Boda, Luiz E Bertassoni
Functional reconstruction of craniofacial defects is a major clinical challenge in craniofacial sciences. The advent of biomaterials is a potential alternative to standard autologous/allogenic grafting procedures to achieve clinically successful bone regeneration. This article discusses various classes of biomaterials currently used in craniofacial reconstruction. Also reviewed are clinical applications of biomaterials as delivery agents for sustained release of stem cells, genes, and growth factors. Recent promising advancements in 3D printing and bioprinting techniques that seem to be promising for future clinical treatments for craniofacial reconstruction are covered...
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886770/dental-cements-for-luting-and-bonding-restorations-self-adhesive-resin-cements
#16
REVIEW
Adriana P Manso, Ricardo M Carvalho
Self-adhesive resin cements combine easy application of conventional luting materials with improved mechanical properties and bonding capability of resin cements. The presence of functional acidic monomers, dual cure setting mechanism, and fillers capable of neutralizing the initial low pH of the cement are essential elements of the material and should be understood when selecting the ideal luting material for each clinical situation. This article addresses the most relevant aspects of self-adhesive resin cements and their potential impact on clinical performance...
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886769/dental-ceramics-for-restoration-and-metal-veneering
#17
REVIEW
Yu Zhang, J Robert Kelly
A survey of the development of dental ceramics is presented to provide a better understanding of the rationale behind the development and clinical indications of each class of ceramic material. Knowledge of the composition, microstructure, and properties of a material is critical for selecting the right material for specific applications. The key to successful ceramic restorations rests on material selection, manufacturing technique, and restoration design, including the balancing of several factors such as residual stresses, tooth contact conditions, tooth size and shape, elastic modulus of the adhesives and tooth structure, and surface state...
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886768/dental-impression-materials-and-techniques
#18
REVIEW
Amit Punj, Despoina Bompolaki, Jorge Garaicoa
Dental impression making is the process of creating a negative form of the teeth and oral tissues, into which gypsum or other die materials can be processed to create working analogues. Contemporary dentistry generates new information every year and digital dentistry is becoming established and influential. Although dentists should stay abreast of new technologies, some of the conventional materials and time-tested techniques remain widely used. It is important to review the impression-making process to ensure that practitioners have up-to-date information about how to safely and effectively capture the exact form of the oral tissues to provide optimal patient management...
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886767/light-curing-in-dentistry
#19
REVIEW
Richard B T Price
The ability to light cure resins 'on demand' in the mouth has revolutionized dentistry. However, there is a widespread lack of understanding of what is required for successful light curing in the mouth. Most instructions simply tell the user to 'light cure for xx seconds' without describing any of the nuances of how to successfully light cure a resin. This article provides a brief description of light curing. At the end, some recommendations are made to help when purchasing a curing light and how to improve the use of the curing light...
October 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28886766/polymer-based-direct-filling-materials
#20
REVIEW
Carmem S Pfeifer
After a brief review of current restorative materials and classifications, this article discusses the latest developments in polymer-based direct filling materials, with emphasis on products and studies available in the last 10 years. This will include the more recent bulk fill composites and self-adhesive materials, for which clinical evidence of success, albeit somewhat limited, is already available. The article also introduces the latest cutting edge research topics on new materials for composite restorations, and an outlook for the future of how those may help to improve the service life of dental composite restorations...
October 2017: Dental Clinics of North America
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