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Methods of Information in Medicine

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https://www.readbyqxmd.com/read/28816343/application-of-n-of-1-experiments-to-test-the-efficacy-of-inactivity-alert-features-in-fitness-trackers-to-increase-breaks-from-sitting-in-older-adults
#1
Dori E Rosenberg, Elyse Kadokura, Margaret E Morris, Anne Renz, Roger M Vilardaga
BACKGROUND: Frequent breaks from sitting could improve health. Many commercially available fitness trackers deliver vibration alerts that could be used to cue sitting breaks. As a potentially pragmatic approach to promote frequent breaks from sitting, we tested the efficacy of inactivity alerts among obese older adults, a highly sedentary population. METHODS: We conducted 10 sequential N-of-1 (single-case) experimental ABA trials. Participants (mean age = 68, mean BMI = 35) were monitored for a baseline phase ("A1") followed by an intervention phase ("B")...
August 16, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28816338/prediction-of-emergency-department-hospital-admission-based-on-natural-language-processing-and-neural-networks
#2
Xingyu Zhang, Joyce Kim, Rachel E Patzer, Stephen R Pitts, Aaron Patzer, Justin D Schrager
OBJECTIVE: To describe and compare logistic regression and neural network modeling strategies to predict hospital admission or transfer following initial presentation to Emergency Department (ED) triage with and without the addition of natural language processing elements. METHODS: Using data from the National Hospital Ambulatory Medical Care Survey (NHAMCS), a cross-sectional probability sample of United States EDs from 2012 and 2013 survey years, we developed several predictive models with the outcome being admission to the hospital or transfer vs...
August 16, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28816337/a-bag-of-concepts-approach-for-biomedical-document-classification-using-wikipedia-knowledge-spanish-english-cross-language-case-study
#3
Marcos A Mouriño-García, Roberto Pérez-Rodríguez, Luis E Anido-Rifón
OBJECTIVES: The ability to efficiently review the existing literature is essential for the rapid progress of research. This paper describes a classifier of text documents, represented as vectors in spaces of Wikipedia concepts, and analyses its suitability for classification of Spanish biomedical documents when only English documents are available for training. We propose the cross-language concept matching (CLCM) technique, which relies on Wikipedia interlanguage links to convert concept vectors from the Spanish to the English space...
August 16, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28726979/chronic-disease-registries-trends-and-challenges
#4
Joachim Schüz, Michael Fored
BACKGROUND: This accompanying editorial is an introduction to the focus theme of "chronic disease registries - trends and challenges". METHODS: A call for papers was announced on the website of Methods of Information in Medicine in April 2016 with submission deadline in September 2016. A peer review process was established to select the papers for the focus theme, managed by two guest editors. RESULTS: Three papers were selected to be included in the focus theme...
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28726975/use-of-an-activity-tracker-to-test-for-a-possible-correlation-of-resting-heart-rate-with-life-events-an-n-of-1-study-of-participant-provided-data
#5
Paul Cooper, Nilmini Wickramasinghe Deakin Edu Au
No abstract text is available yet for this article.
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28726974/back-on-track
#6
Sabine Koch, Olaf Gefeller, Indra N Sarkar, Reinhold Haux
No abstract text is available yet for this article.
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28726973/heart-rate-variability-biofeedback-stress-relief-program-for-depression-a-replicated-single-subject-design
#7
Bregje M A Hartogs, Agna Bartels-Velthuis, Karen Van der Ploeg, Elske H Bos
BACKGROUND: Depressive disorders often have a chronic course and the efficacy of evidence-based treatments may be overestimated. OBJECTIVE: To examine the effectiveness of the Heart Rate Variability Stress Reduction Program (SRP) as a supplement to standard treatment in patients with depressive disorders. METHODS: The SRP was individually administered in eight weekly sessions. Seven participants completed the full protocol and were enrolled in a single-subject ABA multiple baseline experimental design...
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28726971/an-environment-for-guideline-based-decision-support-systems-for%C3%A2-outpatients-monitoring
#8
Elisa M Zini, Giordano Lanzola, Paolo Bossi, Silvana Quaglini
OBJECTIVES: We propose an architecture for monitoring outpatients that relies on mobile technologies for acquiring data. The goal is to better control the onset of possible side effects between the scheduled visits at the clinic. METHODS: We analyze the architectural components required to ensure a high level of abstraction from data. Clinical practice guidelines were formalized with Alium, an authoring tool based on the PROforma language, using SNOMED-CT as a terminology standard...
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28678303/a-comparison-of-discovered-regularities-in-blood-glucose-readings-across-two-data-collection-approaches-used-with-a-type-1-diabetic-youth
#9
Victor Lee, Travis Thurston, Chris Thurston
BACKGROUND: Type 1 diabetes requires frequent testing and monitoring of blood glucose levels in order to determine appropriate type and dosage of insulin administration. This can lead to thousands of individual measurements over the course of a lifetime of a single individual, of which very few are retained as part of a permanent record. The third author, aged 9, and his family have maintained several years of written records since his diagnosis with Type 1 diabetes at age 20 months, and have also recently begun to obtain automated records from a continuous glucose monitor...
July 5, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28612890/technology-in-rehabilitation-comparing-personalised-and-global-classification-methodologies-in-evaluating-the-squat-exercise-with-wearable-imus
#10
Martin A O'Reilly, Darragh Whelan, Tomás E Ward, Eamonn Delahunt, Brian Caulfield
BACKGROUND: The barbell squat is a popularly used lower limb rehabilitation exercise. It is also an integral exercise in injury risk screening protocols. To date athlete/patient technique has been assessed using expensive laboratory equipment or subjective clinical judgement; both of which are not without shortcomings. Inertial measurement units (IMUs) may offer a low cost solution for the objective evaluation of athlete/patient technique. However, it is not yet known if global classification techniques are effective in identifying naturally occurring, minor deviations in barbell squat technique...
June 14, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28590499/can-statistical-machine-learning-algorithms-help-for-classification-of-obstructive-sleep-apnea-severity-to-optimal-utilization-of-polysomnography-resources
#11
Selen Bozkurt, Asli Bostanci, Murat Turhan
OBJECTIVES: The goal of this study is to evaluate the results of machine learning methods for the classification of OSA severity of patients with suspected sleep disorder breathing as normal, mild, moderate and severe based on non-polysomnographic variables: 1) clinical data, 2) symptoms and 3) physical examination. METHODS: In order to produce classification models for OSA severity, five different machine learning methods (Bayesian network, Decision Tree, Random Forest, Neural Networks and Logistic Regression) were trained while relevant variables and their relationships were derived empirically from observed data...
June 7, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28590498/a-multi-way-multi-task-learning-approach-for-multinomial-logistic-regression-an-application-in-joint-prediction-of-appointment-miss-opportunities-across-multiple-clinics
#12
Adel Alaeddini, Seung Hee Hong
OBJECTIVES: Whether they have been engineered for it or not, most healthcare systems experience a variety of unexpected events such as appointment miss-opportunities that can have significant impact on their revenue, cost and resource utilization. In this paper, a multi-way multi-task learning model based on multinomial logistic regression is proposed to jointly predict the occurrence of different types of miss-opportunities at multiple clinics. METHODS: An extension of L1 / L2 regularization is proposed to enable transfer of information among various types of miss-opportunities as well as different clinics...
June 7, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28361158/a-machine-learning-based-method-for-question-type-classification-in-biomedical-question-answering
#13
Mourad Sarrouti, Said Ouatik El Alaoui
BACKGROUND AND OBJECTIVE: Biomedical question type classification is one of the important components of an automatic biomedical question answering system. The performance of the latter depends directly on the performance of its biomedical question type classification system, which consists of assigning a category to each question in order to determine the appropriate answer extraction algorithm. This study aims to automatically classify biomedical questions into one of the four categories: (1) yes/no, (2) factoid, (3) list, and (4) summary...
May 18, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28474729/utilizing-electronic-medical-records-to-discover-changing-trends-of-medical-behaviors-over-time
#14
Liangying Yin, Zhengxing Huang, Wei Dong, Chunhua He, Huilong Duan
OBJECTIVES: Medical behaviors are playing significant roles in the delivery of high quality and cost-effective health services. Timely discovery of changing frequencies of medical behaviors is beneficial for the improvement of health services. The main objective of this work is to discover the changing trends of medical behaviors over time. METHODS: This study proposes a two-steps approach to detect essential changing patterns of medical behaviors from Electronic Medical Records (EMRs)...
May 5, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28451691/tool-supported-interactive-correction-and-semantic-annotation-of-narrative-clinical-reports
#15
Karel Zvára, Marie Tomečková, Jan Peleška, Vojtěch Svátek, Jana Zvárová
OBJECTIVES: Our main objective is to design a method of, and supporting software for, interactive correction and semantic annotation of narrative clinical reports, which would allow for their easier and less erroneous processing outside their original context: first, by physicians unfamiliar with the original language (and possibly also the source specialty), and second, by tools requiring structured information, such as decision-support systems. Our additional goal is to gain insights into the process of narrative report creation, including the errors and ambiguities arising therein, and also into the process of report annotation by clinical terms...
April 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28451689/a-randomized-trial-comparing-classical-participatory-design-to-vandaid-an-interactive-crowdsourcing-platform-to-facilitate-user-centered-design
#16
Kevin R Dufendach, Sabine Koch, Kim M Unertl, Christoph U Lehmann
BACKGROUND: Early involvement of stakeholders in the design of medical software is particularly important due to the need to incorporate complex knowledge and actions associated with clinical work. Standard user-centered design methods include focus groups and participatory design sessions with individual stakeholders, which generally limit user involvement to a small number of individuals due to the significant time investments from designers and end users. OBJECTIVES: The goal of this project was to reduce the effort for end users to participate in co-design of a software user interface by developing an interactive web-based crowdsourcing platform...
April 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28451688/boosting-quality-registries-with-clinical-decision-support-functionality-user-acceptance-of-a-prototype-applied-to-hiv-tb-drug%C3%A2-therapy
#17
Carolina Wannheden, Helena Hvitfeldt-Forsberg, Elena Eftimovska, Katarina Westling, Johan Ellenius
BACKGROUND: The care of HIV-related tuberculosis (HIV/TB) is complex and challenging. Clinical decision support (CDS) systems can contribute to improve quality of care, but more knowledge is needed on factors determining user acceptance of CDS. OBJECTIVES: To analyze physicians' and nurses' acceptance of a CDS prototype for evidence-based drug therapy recommendations for HIV/TB treatment. METHODS: Physicians and nurses were involved in designing a CDS prototype intended for future integration with the Swedish national HIV quality registry...
April 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28451687/reconstruction-of-12-lead-ecg-using-a-single-patch-device
#18
Hong J Lee, Dong S Lee, Hyun B Kwon, Do Y Kim, Kwang S Park
OBJECTIVES: The aim of this study is to develop an optimal electrode system in the form of a small and wearable single-patch ECG monitoring device that allows for the faithful reconstruction of the standard 12-lead ECG. METHODS: The optimized universal electrode positions on the chest and the personalized transformation matrix were determined using linear regression as well as artificial neural networks (ANNs). A total of 24 combinations of 4 neighboring electrodes on 35 channels were evaluated on 19 subjects...
April 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28451686/data-requirements-for-the-correct-identification-of-medication-errors-and-adverse-drug-events-in-patients-presenting-at-an-emergency-department
#19
Bettina Plank-Kiegele, Thomas Bürkle, Fabian Müller, Andrius Patapovas, Anja Sonst, Barbara Pfistermeister, Harald Dormann, Renke Maas
BACKGROUND: Adverse drug events (ADE) involving or not involving medication errors (ME) are common, but frequently remain undetected as such. Presently, the majority of available clinical decision support systems (CDSS) relies mostly on coded medication data for the generation of drug alerts. It was the aim of our study to identify the key types of data required for the adequate detection and classification of adverse drug events (ADE) and medication errors (ME) in patients presenting at an emergency department (ED)...
April 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28361159/evaluation-of-adjusted-and-unadjusted-indirect-comparison-methods-in-benefit-assessment-a-simulation-study-for-time-to-event-endpoints
#20
Sarah Kühnast, Julia Schiffner-Rohe, Jörg Rahnenführer, Friedhelm Leverkus
BACKGROUND: With the Act on the Reform of the Market for Medicinal Products (AMNOG) in Germany, pharmaceutical manufacturers are obliged to submit a dossier demonstrating added benefit of a new drug compared to an appropriate comparator. Underlying evidence was planned for registration purposes and therefore often does not meet the appropriate comparator as defined by the Federal Joint Committee (G-BA). For this reason AMNOG allows indirect comparisons to assess the extent of added benefit...
March 31, 2017: Methods of Information in Medicine
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