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Methods of Information in Medicine

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https://www.readbyqxmd.com/read/30296809/prehospital-telemedical-emergency-management-of-severely-injured-trauma-patients
#1
Patrick A Eder, Birgit Reime, Thomas Wurmb, Uwe Kippnich, Layal Shammas, Asarnusch Rashid
BACKGROUND:  Trauma is a global burden. Emergency medical services (EMS) provide care for individuals who have serious injuries or suffered a major trauma. OBJECTIVE:  This paper provides a comprehensive overview of telemedicine applications in prehospital trauma care. METHODS:  We conducted a systematic review according to PRISMA guidelines. We identified articles by electronic database search (PubMed, EMBASE, the Cochrane Library, CINAHL, SpringerLink, LIVIVO, DARE, IEEE Xplore, Google Scholar and ScienceDirect) using keywords related to prehospital settings, ambulance, telemedicine and trauma...
October 8, 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30296808/analysis-of-machine-learning-algorithms-for-diagnosis-of-diffuse-lung-diseases
#2
Isadora Cardoso, Eliana Almeida, Hector Allende-Cid, Alejandro C Frery, Rangaraj M Rangayyan, Paulo M Azevedo-Marques, Heitor S Ramos
BACKGROUND:  Diffuse lung diseases (DLDs) are a diverse group of pulmonary disorders, characterized by inflammation of lung tissue, which may lead to permanent loss of the ability to breathe and death. Distinguishing among these diseases is challenging to physicians due their wide variety and unknown causes. Computer-aided diagnosis (CAD) is a useful approach to improve diagnostic accuracy, by combining information provided by experts with Machine Learning (ML) methods. OBJECTIVES:  Exploring the potential of dimensionality reduction combined with ML methods for diagnosis of DLDs; improving the classification accuracy over state-of-the-art methods...
October 8, 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30248710/considering-relationship-of-proteins-for-radiotherapy-prognosis-of-bladder-cancer-cells-in-small-data-set
#3
Tung-I Tsai, Yaofeng Zhang, Zhigang Zhang, Gy-Yi Chao, Cheng-Chieh Tsai
BACKGROUND: Radiotherapy has serious side effects and thus requires prudent and cautious evaluation. However, obtaining protein expression profiles is expensive and timeconsuming, making it necessary to develop a theoretical and rational procedure for predicting the radiotherapy outcome for bladder cancer when working with limited data. OBJECTIVE: A procedure for estimating the performance of radiotherapy is proposed in this research. The population domain (range of the population) of proteins and the relationships among proteins are considered to increase prediction accuracy...
September 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30248709/learning-to-detect-cognitive-impairment-through-digital-games-and-machine-learning-techniques
#4
Sonia Valladares-Rodriguez, Roberto Pérez-Rodriguez, J Manuel Fernandez-Iglesias, Luis E Anido-Rifón, David Facal, Carlos Rivas-Costa
OBJECTIVE: Alzheimer's disease (AD) is one of the most prevalent diseases among the adult population. The early detection of Mild Cognitive Impairment (MCI), which may trigger AD, is essential to slow down the cognitive decline process. METHODS: This paper presents a suit of serious games that aims at detecting AD and MCI overcoming the limitations of traditional tests, as they are time-consuming, affected by confounding factors that distort the result and usually administered when symptoms are evident and it is too late for preventive measures...
September 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30248708/prediction-of-sepsis-and-in-hospital-mortality-using-electronic-health-records
#5
Anahita Khojandi, Varisara Tansakul, Xueping Li, Rebecca S Koszalinski, William Paiva
OBJECTIVES: Our goal was to develop predictive models for sepsis and in-hospital mortality using electronic health records (EHRs). We showcased the efficiency of these algorithms in patients diagnosed with pneumonia, a group that is highly susceptible to sepsis. METHODS: We retrospectively analyzed the Health Facts® (HF) dataset to develop models to predict mortality and sepsis using the data from the first few hours after admission. In addition, we developed models to predict sepsis using the data collected in the last few hours leading to sepsis onset...
September 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30248707/quality-of-the-icd-11-beta-draft-from-the-german-perspective-evaluation-based-on-the-alphabet-of-icd-10-gm-2017
#6
Jürgen Stausberg
OBJECTIVES: The German Association for Medical Informatics, Biometry and Epidemiology implemented a field test for the ICD-11 Beta Draft. Aim was to analyze completeness and appropriateness of the ICD-11 Beta Draft in its entire breadth. METHODS: Starting point was the synonym thesaurus ("Alphabet") of the German modification of ICD-10. The Alphabet included a list of diagnoses terms that supports the coding of diagnoses with ICD-10. A sample of 60,328 diagnosis terms was drawn to be mapped to the ICD-11 Beta Draft...
September 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30248706/development-of-an-open-metadata-schema-for-clinical-pathway-opencp-in-china
#7
Wei Xu, Yanxin Zhu, Yibing Geng
BACKGROUND: By the end of the first quarter of 2017, 1212 standard Clinical Pathways (CPs) had been developed and implemented in China since 2009, however, Chinese standard CPs are still paper-based CPs. OBJECTIVES: To optimize the data structure and content of Chinese standard CPs based on Chinese health standards by two-level modeling approach and archetype method, and develop an Open Metadata Schema for Clinical Pathway (openCP) in China. METHODS: We chose 43 diseases covering 7 departments of internal medicine as samples and source materials including Respiratory, Gastroenterology, Neurology, Cardiology, Nephrology, Endocrinology, and Hematology, and we followed 4 steps to develop openCP: identify reference model of openCP; develop archetype models; standardize archetype terms and metadata; and evaluate its functionality...
September 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30016818/german-medical-informatics-initiative
#8
EDITORIAL
Sebastian C Semler, Frank Wissing, Ralf Heyder
This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. The Medical Informatics Initiative (MII) was launched within the scope of the German Federal Ministry of Education and Research's (BMBF) Medical Informatics Funding Scheme, with the goal of developing infrastructure for the integration of clinical data from patient care and medical research in Germany. Its work is to be performed over the course of a decade (2016-2025) across three funding phases, with the first two concentrating on university hospitals...
July 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30016817/german-medical-informatics-initiative-unlocking-data-for-research-and-health-care
#9
EDITORIAL
Stefanie Gehring, René Eulenfeld
This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. The Medical Informatics Initiative of the German Federal Ministry of Education and Research will make use of the potential of digitalization in the field of medicine in Germany. The aim is to improve the possibilities for medical research and patient care through innovative IT solutions. In an initial step, data integration centres will be set up at university hospitals to ensure the technical and organizational conditions necessary for multi-site exchange of data between health care and clinical and biomedical research...
July 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30016816/health-information-systems-from-present-to-future
#10
EDITORIAL
Reinhold Haux
This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. Funded by the German Federal Ministry of Education and Research with about 150 million Euro in its currently starting development and networking phase this initiative has already a significant impact on the development of health information systems in Germany. In this Focus Theme two editorials introduce this initiative, one from the viewpoint of its funding institution and one from the initiative's accompanying institutions...
July 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30016815/smart-medical-information-technology-for-healthcare-smith
#11
Alfred Winter, Sebastian Stäubert, Danny Ammon, Stephan Aiche, Oya Beyan, Verena Bischoff, Philipp Daumke, Stefan Decker, Gert Funkat, Jan E Gewehr, Armin de Greiff, Silke Haferkamp, Udo Hahn, Andreas Henkel, Toralf Kirsten, Thomas Klöss, Jörg Lippert, Matthias Löbe, Volker Lowitsch, Oliver Maassen, Jens Maschmann, Sven Meister, Rafael Mikolajczyk, Matthias Nüchter, Mathias W Pletz, Erhard Rahm, Morris Riedel, Kutaiba Saleh, Andreas Schuppert, Stefan Smers, André Stollenwerk, Stefan Uhlig, Thomas Wendt, Sven Zenker, Wolfgang Fleig, Gernot Marx, André Scherag, Markus Löffler
INTRODUCTION: This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. "Smart Medical Information Technology for Healthcare (SMITH)" is one of four consortia funded by the German Medical Informatics Initiative (MI-I) to create an alliance of universities, university hospitals, research institutions and IT companies. SMITH's goals are to establish Data Integration Centers (DICs) at each SMITH partner hospital and to implement use cases which demonstrate the usefulness of the approach...
July 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30016814/miracum-medical-informatics-in-research-and-care-in-university-medicine
#12
Hans-Ulrich Prokosch, Till Acker, Johannes Bernarding, Harald Binder, Martin Boeker, Melanie Boerries, Philipp Daumke, Thomas Ganslandt, Jürgen Hesser, Gunther Höning, Michael Neumaier, Kurt Marquardt, Harald Renz, Hermann-Josef Rothkötter, Carmen Schade-Brittinger, Paul Schmücker, Jürgen Schüttler, Martin Sedlmayr, Hubert Serve, Keywan Sohrabi, Holger Storf
INTRODUCTION: This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. Similar to other large international data sharing networks (e.g. OHDSI, PCORnet, eMerge, RD-Connect) MIRACUM is a consortium of academic and hospital partners as well as one industrial partner in eight German cities which have joined forces to create interoperable data integration centres (DIC) and make data within those DIC available for innovative new IT solutions in patient care and medical research...
July 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30016813/highmed-an-open-platform-approach-to-enhance-care-and-research-across-institutional-boundaries
#13
Birger Haarbrandt, Björn Schreiweis, Sabine Rey, Ulrich Sax, Simone Scheithauer, Otto Rienhoff, Petra Knaup-Gregori, Udo Bavendiek, Christoph Dieterich, Benedikt Brors, Inga Kraus, Caroline Marieken Thoms, Dirk Jäger, Volker Ellenrieder, Björn Bergh, Ramin Yahyapour, Roland Eils, HiGHmed Consortium, Michael Marschollek
INTRODUCTION: This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. HiGHmed brings together 24 partners from academia and industry, aiming at improvements in care provision, biomedical research and epidemiology. By establishing a shared information governance framework, data integration centers and an open platform architecture in cooperation with independent healthcare providers, the meaningful reuse of data will be facilitated...
July 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/30016812/data-integration-for-future-medicine-difuture
#14
Fabian Prasser, Oliver Kohlbacher, Ulrich Mansmann, Bernhard Bauer, Klaus A Kuhn
INTRODUCTION: This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. Future medicine will be predictive, preventive, personalized, participatory and digital. Data and knowledge at comprehensive depth and breadth need to be available for research and at the point of care as a basis for targeted diagnosis and therapy. Data integration and data sharing will be essential to achieve these goals. For this purpose, the consortium Data Integration for Future Medicine (DIFUTURE) will establish Data Integration Centers (DICs) at university medical centers...
July 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29956297/technology-informatics-guiding-education-reform-tiger
#15
Ursula Hübner, Toria Shaw, Johannes Thye, Nicole Egbert, Heimar de Fatima Marin, Polun Chang, Siobhán O'Connor, Karen Day, Michelle Honey, Rachelle Blake, Evelyn Hovenga, Diane Skiba, Marion J Ball
BACKGROUND: While health informatics recommendations on competencies and education serve as highly desirable corridors for designing curricula and courses, they cannot show how the content should be situated in a specific and local context. Therefore, global and local perspectives need to be reconciled in a common framework. OBJECTIVES: The primary aim of this study is therefore to empirically define and validate a framework of globally accepted core competency areas in health informatics and to enrich this framework with exemplar information derived from local educational settings...
June 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29911300/confounding-factors-in-ecg-based-detection-of-sleep-disordered-breathing
#16
Christoph Maier, Hartmut Dickhaus
OBJECTIVES: To assess the relevance of various potential confounding factors (comorbidities, obesity, body position, ECG lead, respiratory event type and sleep stage) on the detectability of sleep-related breathing disorders from the ECG. METHODS: A set of 140 simultaneous recordings of polysomnograms and 8-channel Holter ECGs taken from 121 patients with suspected sleep related breathing disorders is stratified with respect to the named factors. Minute-by-minute apnea detection performance is assessed using separate receiver operating characteristics curves for each of the subgroups...
May 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29801178/ad-hoc-information-extraction-for-clinical-data-warehouses
#17
Georg Dietrich, Jonathan Krebs, Georg Fette, Maximilian Ertl, Mathias Kaspar, Stefan Störk, Frank Puppe
BACKGROUND: Clinical Data Warehouses (CDW) reuse Electronic health records (EHR) to make their data retrievable for research purposes or patient recruitment for clinical trials. However, much information are hidden in unstructured data like discharge letters. They can be preprocessed and converted to structured data via information extraction (IE), which is unfortunately a laborious task and therefore usually not available for most of the text data in CDW. OBJECTIVES: The goal of our work is to provide an ad hoc IE service that allows users to query text data ad hoc in a manner similar to querying structured data in a CDW...
May 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29719923/application-of-empirical-mode-decomposition-to-mother-and-infant-physical-activity
#18
Etsuko Shimizu, Toru Nakamura, Jinhyuk Kim, Kazuhiro Yoshiuchi, Yoshiharu Yamamoto
BACKGROUND: The mutual dependencies between mother and infant circadian rhythms are important for examining disturbances of maternal circadian rhythms, which are considered substantial risk factors for the development of maternal depression during childrearing periods. OBJECTIVES: We characterized the mutual dependencies of maternal-infant circadian rhythms by an index of synchronization properties and then tested the hypothesis that such an index, specifically the instantaneous phase differences between their rhythms, is associated with maternal mental health...
May 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29719922/scattering-transform-of-heart-rate-variability-for-the-prediction-of-ischemic-stroke-in-patients-with-atrial-fibrillation
#19
Roberto Leonarduzzi, Patrice Abry, Herwig Wendt, Ken Kiyono, Yoshiharu Yamamoto, Eiichi Watanabe, Junichiro Hayano
BACKGROUND: Atrial fibrillation (AF) is an identified risk factor for ischemic strokes (IS). AF causes a loss in atrial contractile function that favors the formation of thrombi, and thus increases the risk of stroke. Also, AF produces highly irregular and complex temporal dynamics in ventricular response RR intervals. Thus, it is hypothesized that the analysis of RR dynamics could provide predictors for IS. However, these complex and nonlinear dynamics call for the use of advanced multiscale nonlinear signal processing tools...
May 2018: Methods of Information in Medicine
https://www.readbyqxmd.com/read/29719921/analysis-of-instantaneous-linear-nonlinear-and-complex-cardiovascular-dynamics-from-videophotoplethysmography
#20
Gaetano Valenza, Luca Iozzia, Luca Cerina, Luca Mainardi, Riccardo Barbieri
BACKGROUND: There is a fast growing interest in the use of non-contact devices for health and performance assessment in humans. In particular, the use of non-contact videophotoplethysmography (vPPG) has been recently demonstrated as a feasible way to extract cardiovascular information. Nevertheless, proper validation of vPPG-derived heartbeat dynamics is still missing. OBJECTIVE: We aim to an in-depth validation of time-varying, linear and nonlinear/complex dynamics of the pulse rate variability extracted from vPPG...
May 2018: Methods of Information in Medicine
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