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Methods of Information in Medicine

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https://www.readbyqxmd.com/read/28361159/evaluation-of-adjusted-and-unadjusted-indirect-comparison-methods-in-benefit-assessment-a-simulation-study-for-time-to-event-endpoints
#1
Sarah Kühnast, Julia Schiffner-Rohe, Jörg Rahnenführer, Friedhelm Leverkus
BACKGROUND: With the Act on the Reform of the Market for Medicinal Products (AMNOG) in Germany, pharmaceutical manufacturers are obliged to submit a dossier demonstrating added benefit of a new drug compared to an appropriate comparator. Underlying evidence was planned for registration purposes and therefore often does not meet the appropriate comparator as defined by the Federal Joint Committee (G-BA). For this reason AMNOG allows indirect comparisons to assess the extent of added benefit...
March 31, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28361158/a-machine-learning-based-method-for-question-type-classification-in-biomedical-question-answering
#2
Mourad Sarrouti, Said Ouatik El Alaoui
BACKGROUND AND OBJECTIVE: Biomedical question type classification is one of the important components of an automatic biomedical question answering system. The performance of the latter depends directly on the performance of its biomedical question type classification system, which consists of assigning a category to each question in order to determine the appropriate answer extraction algorithm. This study aims to automatically classify biomedical questions into one of the four categories: (1) yes/no, (2) factoid, (3) list, and (4) summary...
March 31, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28361157/integration-of-hospital-information-and-clinical-decision-support-systems-to-enable-the-reuse-of-electronic-health-record-data
#3
Georgy Kopanitsa
BACKGROUND: The efficiency and acceptance of clinical decision support systems (CDSS) can increase if they reuse medical data captured during health care delivery. High heterogeneity of the existing legacy data formats has become the main barrier for the reuse of data. Thus, we need to apply data modeling mechanisms that provide standardization, transformation, accumulation and querying medical data to allow its reuse. OBJECTIVES: In this paper, we focus on the interoperability issues of the hospital information systems (HIS) and CDSS data integration...
March 31, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28361156/mapping-acute-coronary-syndrome-registries-to-snomed-ct-a-comparative-study-between-malaysia-and-sweden
#4
Ismat Mohd Sulaiman, Daniel Karlsson, Sabine Koch
BACKGROUND: Malaysia and Sweden have mapped their acute coronary syndrome registries using SNOMED CT. Since similar-purposed patient registries can be expected to collect similar data, these data should be mapped to the same SNOMED CT codes despite the different languages used. Previous studies have however shown variations in mapping between different mappers but the reasons behind these variations and the influence of different mapping approaches are still unknown. OBJECTIVES: To analyze similar-purposed registries and their registry-to-SNOMED CT maps, using two national acute coronary syndrome registries as examples, to understand the reasons for mapping similarities and differences as well as their implications...
March 31, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28244549/relating-complexity-and-error-rates-of-ontology-concepts-more-complex-ncit-concepts-have-more-errors
#5
Hua Min, Ling Zheng, Yehoshua Perl, Michael Halper, Sherri De Coronado, Christopher Ochs
OBJECTIVES: Ontologies are knowledge structures that lend support to many health-information systems. A study is carried out to assess the quality of ontological concepts based on a measure of their complexity. The results show a relation between complexity of concepts and error rates of concepts. METHODS: A measure of lateral complexity defined as the number of exhibited role types is used to distinguish between more complex and simpler concepts. Using a framework called an area taxonomy, a kind of abstraction network that summarizes the structural organization of an ontology, concepts are divided into two groups along these lines...
February 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28244548/assessing-the-coverage-of-e-health-services-in-sub-saharan-africa-a-systematic-review-and-analysis
#6
Davies Adeloye, Taiwo Adigun, Sanjay Misra, Nicholas Omoregbe
BACKGROUND: E-Health has attracted growing interests globally. The relative lack of facilities, skills, funds and information on existing e-Health initiatives has affected progress on e-Health in Africa. OBJECTIVES: To review publicly available literature on e-Health in sub-Saharan Africa (sSA) towards providing information on existing and ongoing e-Health initiatives in the region. METHODS: Searches of relevant literature were conducted on Medline, EMBASE and Global Health, with search dates set from 1990 to 2016...
February 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28244546/structuring-legacy-pathology-reports-by-openehr-archetypes-to-enable-semantic-querying
#7
Stefan Kropf, Peter Krücken, Wolf Mueller, Kerstin Denecke
BACKGROUND: Clinical information is often stored as free text, e.g. in discharge summaries or pathology reports. These documents are semi-structured using section headers, numbered lists, items and classification strings. However, it is still challenging to retrieve relevant documents since keyword searches applied on complete unstructured documents result in many false positive retrieval results. OBJECTIVES: We are concentrating on the processing of pathology reports as an example for unstructured clinical documents...
February 28, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28220929/increasing-the-efficiency-on-producing-radiology-reports-for-breast-cancer-diagnosis-by-means-of-structured-reports-a-comparative-study
#8
J Damian Segrelles, Rosana Medina, Ignacio Blanquer, Luis Martí-Bonmatí
BACKGROUND: Radiology reports are commonly written on free-text using voice recognition devices. Structured reports (SR) have a high potential but they are usually considered more difficult to fill-in so their adoption in clinical practice leads to a lower efficiency. However, some studies have demonstrated that in some cases, producing SRs may require shorter time than plain-text ones. This work focuses on the definition and demonstration of a methodology to evaluate the productivity of software tools for producing radiology reports...
February 21, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28220926/genetic-testing-for-autism-spectrum-disorder-is-lacking-evidence-of-cost-effectiveness-a-systematic-review
#9
Andreas Ziegler, Wolfgang Rudolph-Rothfeld, Reinhard Vonthein
BACKGROUND: Autism Spectrum Disorder (ASD) is a highly heritable neural development disorder characterized by social impairment. The earlier the diagnosis is made, the higher are the chances of obtaining relief of symptoms. A very early diagnosis uses molecular genetic tests, which are also offered commercially. OBJECTIVE: Systematic review of the economic impact of genetic tests in ASD. METHODS: We performed a systematic search of databases Pubmed, Medline, Cochrane, Econlit and the NHS Center for Reviews and Dissemination for articles in English and German from January 1, 2000 to December 31, 2015...
February 21, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28244547/the-made-reference-information-model-for-interoperable-pervasive-telemedicine-systems
#10
Nick L S Fung, Valerie M Jones, Hermie J Hermens
OBJECTIVES: The main objective is to develop and validate a reference information model (RIM) to support semantic interoperability of pervasive telemedicine systems. The RIM is one component within a larger, computer-interpretable "MADE language" developed by the authors in the context of the MobiGuide project. To validate our RIM, we applied it to a clinical guideline for patients with gestational diabetes mellitus (GDM). METHODS: The RIM is derived from a generic data flow model of disease management which comprises a network of four types of concurrent processes: Monitoring (M), Analysis (A), Decision (D) and Effectuation (E)...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28244545/the-effect-of-balance-training-on-postural-control-in-patients-with-parkinson-s-disease-using-a-virtual-rehabilitation-system
#11
Sergio Albiol-Pérez, José-Antonio Gil-Gómez, María-Teresa Muñoz-Tomás, Hermenegildo Gil-Gómez, Raquel Vial-Escolano, José-Antonio Lozano-Quilis
OBJECTIVES: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor clinical alterations among others. Postural problems have serious consequences for patients, not only limiting their daily life but also increasing some risks, like the risk of fall. Inadequate postural control and postural instability is a major problem in PD patients. A Virtual Motor Rehabilitation System (VMR) has been tested in patients with PD in the intervention period. Our purpose was to analyze the evolution of the spatial postural control during the intervention period, to see if there are any changes caused precisely by this intervention...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28244544/technologies-solutions-schemes-for-patients-rehabilitation-methodologies-models-and-algorithms
#12
Habib M Fardoun, Abdulfattah S Mashat
OBJECTIVE: The present editorial is part of the focus theme of Methods of Information in Medicine entitled "Technologies solutions schemes for Patients' Rehabilitation: Methodologies, Models and Algorithms". The focus theme aims to present nowadays most innovative solutions to improve patients' rehabilitation by applying and using sophisticated and pioneering Information and Communication Technologies (ICT) and human factors. METHODS: The focus theme explores the different existent research works and tools used, applied and developed for incapable people in terms of rehabilitation and health care, as to look into the extent methodologies, models and algorithms by means of ICT in this process...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28220928/malt-combined-motor-and-language-therapy-tool-for-brain-injury-patients-using-kinect
#13
Maitreyee Wairagkar, Rachel McCrindle, Holly Robson, Lotte Meteyard, Malcom Sperrin, Andy Smith, Moyra Pugh
BACKGROUND: The functional connectivity and structural proximity of elements of the language and motor systems result in frequent co-morbidity post brain injury. Although rehabilitation services are becoming increasingly multidisciplinary and "integrated", treatment for language and motor functions often occurs in isolation. Thus, behavioural therapies which promote neural reorganisation do not reflect the high intersystem connectivity of the neurologically intact brain. As such, there is a pressing need for rehabilitation tools which better reflect and target the impaired cognitive networks...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28220927/evaluation-results-of-an-ontology-based-design-model-of-virtual-environments-for-upper-limb-motor-rehabilitation-of-stroke-patients
#14
Cristina Ramírez-Fernández, Alberto L Morán, Eloísa García-Canseco, Jorge R Gómez-Montalvo
OBJECTIVES: 1) To enhance the content of an ontology for designing virtual environments (VEs) for upper limb motor rehabilitation of stroke patients according to the suggestions and comments of rehabilitation specialists and software developers, 2) to characterize the perceived importance level of the ontology, 3) to determine the perceived usefulness of the ontology, and 4) to identify the safety characteristics of the ontology for VEs design according to the rehabilitation specialists...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28116417/an-immersive-virtual-reality-platform-to-enhance-walking-ability-of-children-with-acquired-brain-injuries
#15
Emilia Biffi, Elena Beretta, Ambra Cesareo, Cristina Maghini, Anna C Turconi, Gianluigi Reni, Sandra Strazzer
BACKGROUND: Acquired brain injury (ABI) may result in lifelong impairment of physical, cognitive, and psychosocial functions. Several rehabilitative treatments are often needed to support walking recovery, thus participants' engagement becomes a crucial aspect, especially when patients are children. In the last few years, traditional physiotherapy (PT) has been flanked by innovative technologies for rehabilitation in the fields of robotics and Virtual Reality (VR). Preliminary results have shown interesting perspectives in the use of a VR system, the GRAIL (Gait Real-time Analysis Interactive Lab), in improving walking abilities in a small group of children with ABI, although further insights are needed about its use as rehabilitative tool in the pediatric population...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28116415/can-3d-gamified-simulations-be-valid-vocational-training-tools-for-persons-with-intellectual-disability-an-experiment-based-on-a-real-life-situation
#16
Ariel von Barnekow, Núria Bonet-Codina, Dani Tost
OBJECTIVE: To investigate if 3D gamified simulations can be valid vocational training tools for persons with intellectual disability. METHODS: A 3D gamified simulation composed by a set of training tasks for cleaning in hostelry was developed in collaboration with professionals of a real hostel and pedagogues of a special needs school. The learning objectives focus on the acquisition of vocabulary skills, work procedures, social abilities and risk prevention. Several accessibility features were developed to make the tasks easy to do from a technological point-of-view...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28116414/cognitive-training-through-mhealth-for-individuals-with-substance-use-disorder
#17
Pedro Gamito, Jorge Oliveira, Paulo Lopes, Rodrigo Brito, Diogo Morais, Cristina Caçoete, André Leandro, Teresa Almeida, Hugo Oliveira
BACKGROUND: Heroin addiction has a negative impact on cognitive functions, and even recovering addicts suffer from cognitive impairment. Recent approaches to cognitive intervention have been taking advantage of what new technologies have to offer. OBJECTIVES: We report a study testing the efficacy of a serious games approach using tablets to stimulate and rehabilitate cognitive functions in recovering addicts. METHODS: A small-scale cognitive training program with serious games was run with a sample of 14 male heroin addicts undergoing a rehabilitation program...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28116413/using-actigraphy-and-mhealth-systems-for-an-objective-analysis-of%C3%A2-sleep-quality-on-systemic-lupus-erythematosus-patients
#18
Sara Balderas-Díaz, M Pilar Martínez, Gabriel Guerrero-Contreras, Elena Miró, Kawtar Benghazi, Ana I Sánchez, José Luis Garrido, Germán Prados
INTRODUCTION: Although sleep alterations can be an important factor contributing to the clinical state of Systemic Lupus Erythematosus, there are no studies to adequately assess sleep quality in this type of disease. OBJECTIVES: The aim of this work is to analyse the sleep quality of Systemic Lupus Erythematous (SLE) patients based on more objective information provided by actigraphy and mobile systems. The idea is to carry out a comprehensive study by analysing how environmental conditions and factors can affect sleep quality...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27922660/combined-vision-and-wearable-sensors-based-system-for-movement-analysis-in-rehabilitation
#19
Sofija Spasojević, Tihomir V Ilić, Slađan Milanović, Veljko Potkonjak, Aleksandar Rodić, José Santos-Victor
BACKGROUND: Traditional rehabilitation sessions are often a slow, tedious, disempowering and non-motivational process, supported by clinical assessment tools, i.e. evaluation scales that are prone to subjective rating and imprecise interpretation of patient's performance. Poor patient motivation and insufficient accuracy are thus critical factors that can be improved by new sensing / processing technologies. OBJECTIVES: We aim to develop a portable and affordable system, suitable for home rehabilitation, which combines vision-based and wearable sensors...
March 23, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/27922659/eye-movement-analysis-and-cognitive-assessment-the-use-of-comparative-visual-search-tasks-in-a-non-immersive-vr-application
#20
Pedro J Rosa, Pedro Gamito, Jorge Oliveira, Diogo Morais, Matthew Pavlovic, Olivia Smyth, Inês Maia, Tiago Gomes
BACKGROUND: An adequate behavioral response depends on attentional and mnesic processes. When these basic cognitive functions are impaired, the use of non-immersive Virtual Reality Applications (VRAs) can be a reliable technique for assessing the level of impairment. However, most non-immersive VRAs use indirect measures to make inferences about visual attention and mnesic processes (e.g., time to task completion, error rate). OBJECTIVES: To examine whether the eye movement analysis through eye tracking (ET) can be a reliable method to probe more effectively where and how attention is deployed and how it is linked with visual working memory during comparative visual search tasks (CVSTs) in non-immersive VRAs...
March 23, 2017: Methods of Information in Medicine
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