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American Journal of Cardiology

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https://www.readbyqxmd.com/read/29195826/some-cardiologists-perspective-on-past-current-and-future-of-sleep-medicine
#1
EDITORIAL
Younghoon Kwon, Lee A Surkin, Chi-Hang Lee
An accumulating body of evidence has highlighted the importance of sleep in cardiovascular health. Sleep apnea (SA) is a highly common condition in patients with cardiovascular comorbidities. Although awareness about the importance of diagnosis and treatment of SA among cardiologists has increased, incorporating it into daily practice has been challenging. We briefly review the current state of sleep medicine in the United States and provide views on how the cardiology community can more actively participate in SA care to deliver higher quality of care...
November 28, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29169605/relation-of-stroke-and-bleeding-risk-profiles-to-efficacy-and-safety-of-edoxaban-for-cardioversion-of-atrial-fibrillation-from-the-edoxaban-versus-warfarin-in-subjects-undergoing-cardioversion-of-atrial-fibrillation-ensure-af-study
#2
Gregory Y H Lip, Jose L Merino, G Andrei Dan, Sakis Themistoclakis, Kenneth A Ellenbogen, Raffaele De Caterina, Assen Goudev, James Jin, Michael Melino, Shannon M Winters, Andreas Goette
In the EdoxabaN versus warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study, edoxaban was compared with enoxaparin-warfarin in patients who underwent electrical cardioversion of nonvalvular atrial fibrillation, showing comparable low rates of bleeding and thromboembolism. The present study is an ancillary analysis investigating differences in relation to stroke and bleeding risk profiles. It also determined the relation of patients' clinical risk profiles to the quality of anticoagulation control in the warfarin arm...
November 20, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29153771/outcome-of-patients-with-in-hospital-ventricular-tachycardia-and-ventricular-fibrillation-arrest-while-using-a-wearable-cardioverter-defibrillator
#3
Kenneth A Ellenbogen, Chingping Wan, David M Shavelle
In-hospital sudden cardiac arrests occurring during nighttime and weekend hours or within unmonitored hospital areas have been reported to have a poorer outcomes than monitored cardiac arrest. This study sought to assess the outcome of in-hospital ventricular tachycardia (VT) and ventricular fibrillation (VF) arrest by time of day, day of week, and within-hospital location when using a wearable cardioverter defibrillator (WCD). We retrospectively identified and reviewed consecutive in-hospital VT/VF arrests from January 2011 to May 2015 experienced by patients wearing a WCD using the manufacturer's postmarket registry...
November 16, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29197472/frequency-of-inverted-electrocardiographic-t-waves-cerebral-t-waves-in-patients-with-acute-strokes-and-their-relation-to-left-ventricular-wall-motion-abnormalities
#4
Jeremy Stone, Victor Mor-Avi, Agnieszka Ardelt, Roberto M Lang
Transient, symmetric, and deep inverted electrocardiogram (ECG) T waves in the setting of stroke, commonly referred to as cerebral T waves, are rare, and the underlying mechanism is unclear. Our study aimed to test the hypothesis that cerebral T waves are associated with transient cardiac dysfunction. This retrospective study included 800 patients admitted with the primary diagnosis of hemorrhagic or ischemic stroke. ECGs were examined for cerebral T waves, defined as T-wave inversion of ≥5 mm depth in ≥4 contiguous precordial leads...
November 14, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29174490/risk-of-cardiac-events-associated-with-antidepressant-therapy-in-patients-with-long-qt-syndrome
#5
Meng Wang, Barbara Szepietowska, Bronislava Polonsky, Scott McNitt, Arthur J Moss, Wojciech Zareba, David S Auerbach
Patients with long QT syndrome (LQTS) are at a high risk of cardiac events. Many patients with LQTS are treated with antidepressant drugs (ADs). We investigated the LQTS genotype-specific risk of recurrent cardiac arrhythmic events (CAEs) associated with AD therapy. The study included 59 LQT1 and 72 LQT2 patients from the Rochester-based LQTS Registry with corrected QT (QTc) prolongation and a history of AD therapy. Using multivariate Anderson-Gill models, we estimated the LQTS genotype-specific risk of recurrent CAEs (ventricular tachyarrhythmias, aborted cardiac arrest, or sudden cardiac death) associated with time-dependent ADs...
November 13, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29221604/effect-of-evolocumab-on-lipoprotein-particles
#6
Peter P Toth, Naveed Sattar, Dirk J Blom, Seth S Martin, Steven R Jones, Maria Laura Monsalvo, Mary Elliott, Mike Davis, Ransi Somaratne, David Preiss
The level of low-density lipoprotein cholesterol (LDL-C) reflects the cholesterol carried mainly by low-density lipoprotein particles (LDL-P). LDL-C, however, does not always correlate with LDL-P because of the variable amounts of cholesterol per particle. Consideration of LDL-P concentrations in addition to LDL-C may help guide therapeutic decisions in a select number of patients. Evolocumab is a fully human monoclonal antibody directed against proprotein convertase subtilisin-kexin type 9 that lowers both LDL-C and cardiovascular events...
November 8, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29203036/comparison-of-the-prognostic-usefulness-of-the-european-society-of-cardiology-and-american-heart-association-american-college-of-cardiology-foundation-risk-stratification-systems-for-patients-with-hypertrophic-cardiomyopathy
#7
Kevin M W Leong, Ji-Jian Chow, Fu Siong Ng, Emanuela Falaschetti, Norman Qureshi, Michael Koa-Wing, Nicholas W F Linton, Zachary I Whinnett, David C Lefroy, D Wyn Davies, Phang Boon Lim, Nicholas S Peters, Prapa Kanagaratnam, Amanda M Varnava
Implantable cardiodefibrillators (ICDs) have proven benefit in preventing sudden cardiac death (SCD) in hypertrophic cardiomyopathy (HC), making risk stratification essential. Data on the predictive accuracy on the European Society of Cardiology (ESC) risk scoring system have been conflicting. We independently evaluated the ESC risk scoring system in our cohort of patients with HC from a large tertiary center and compared this with previous guidance by the American College of Cardiology Foundation and Heart Association (ACCF/AHA)...
November 7, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29223288/prediction-of-delayed-atrioventricular-block-and-pacemaker-implantation-after-transcatheter-aortic-valve-replacement-with-corevalve
#8
LETTER
Akihiro Kobayashi, Naoki Misumida
No abstract text is available yet for this article.
November 6, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29191569/safety-and-efficacy-of-beta-blockers-in-cocaine-using-patients-with-heart-failure
#9
LETTER
John R Richards
No abstract text is available yet for this article.
November 6, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29191565/magnetic-resonance-imaging-correlates-of-left-bundle-branch-disease-in-patients-with-nonischemic-cardiomyopathy
#10
Chrysanthos Grigoratos, Riccardo Liga, Elena Bennati, Andrea Barison, Giancarlo Todiere, Giovanni Donato Aquaro, Matteo Dell'Omodarme, Michele Emdin, Pier Giorgio Masci
The pathologic correlates of intraventricular conduction delays in patients with nonischemic cardiomyopathy (NIC) have been scarcely investigated. We assessed left ventricular (LV) structural, functional, and tissue abnormalities associated with intraventricular conduction left bundle disease (LBD), including left anterior hemiblock or complete left bundle branch block, in a cohort of patients with NIC submitted to cardiovascular magnetic resonance. Twelve-lead electrocardiogram and cardiovascular magnetic resonance were performed in 196 consecutive patients with NIC...
November 6, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29198985/clinical-and-psychological-drivers-of-perceived-health-status-in-adults-with-congenital-heart-disease
#11
Jong Mi Ko, Kristen M Tecson, Vanessa Al Rashida, Sandeep Sodhi, Josh Saef, Mehwish Mufti, Kamila S White, Philip A Ludbrook, Ari M Cedars
The factors having the greatest impact on self-reported health status in adults with congenital heart disease (ACHD) remain incompletely studied. We conducted a single-site, cross-sectional study of ACHD patients followed at the Center for ACHD at Washington University School of Medicine, including retrospectively gathered clinical data and psychometric and health status assessments completed at the time of enrollment. To identify primary drivers of perceived health status, we investigated the impact of the demographic, clinical, and psychological variables on self-reported health status as assessed using the Rand 36-Item Short Form Health Survey...
November 3, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29197473/electrocardiographic-findings-in-patients-with-acute-coronary-syndrome-presenting-with-out-of-hospital-cardiac-arrest
#12
Bradley Sarak, Shaun G Goodman, David Brieger, Chris P Gale, Nigel S Tan, Andrzej Budaj, Graham C Wong, Thao Huynh, Mary K Tan, Jacob A Udell, Akshay Bagai, Keith A A Fox, Andrew T Yan
We sought to characterize presenting electrocardiographic findings in patients with acute coronary syndromes (ACSs) and out-of-hospital cardiac arrest (OHCA). In the Global Registry of Acute Coronary Events and Canadian ACS Registry I, we examined presenting and 24- to 48-hour follow-up ECGs (electrocardiogram) of ACS patients who survived to hospital admission, stratified by presentation with OHCA. We assessed the prevalence of ST-segment deviation and bundle branch blocks (assessed by an independent ECG core laboratory) and their association with in-hospital and 6-month mortality among those with OHCA...
November 3, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29195828/blood-pressure-control-in-patients-presenting-with-type-b-aortic-dissection
#13
LETTER
Tomoyuki Kawada
No abstract text is available yet for this article.
November 2, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29191564/dynamic-st-segment-abnormality
#14
Elias B Hanna, Paul A LeLorier, D Luke Glancy
A 37-year-old man came to the emergency department because of several days of intermittent chest pain. An electrocardiogram (ECG) showed sinus rhythm, left atrial and left ventricular enlargement, and an early repolarization pattern. A second ECG recorded 10 minutes later was strikingly different, with ST-segment elevation and large upright T waves in the anterior precordial leads, interpreted as evidence of an ST-segment elevation myocardial infarction, and the cardiac catheterization team was activated. Closer inspection of the ECG, however, disclosed that the changes were because of intermittent ventricular pre-excitation of the Wolff-Parkinson-White type, and no electrocardiographic, echocardiographic, or serum markers of myocardial infarction were found...
November 2, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29241969/relation-of-ectopic-fat-with-atherosclerotic-cardiovascular-disease-risk-score-in-south-asians-living-in-the-united-states-from-the-mediators-of-atherosclerosis-in-south-asians-living-in-america-masala-study
#15
Morgana Mongraw-Chaffin, Unjali P Gujral, Alka M Kanaya, Namratha R Kandula, John Jeffrey Carr, Cheryl A M Anderson
Few studies have investigated the association between ectopic fat from different depots and cardiovascular risk scores and their components in the same population, and none have investigated these relations in South Asians. In a cross-sectional analysis of 796 participants in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study who had measurements of visceral, subcutaneous, pericardial, hepatic, and intermuscular fat from abdominal and cardiac computed tomography scans, we used linear regression to determine the associations of 1 standard deviation difference in each ectopic fat depot with pooled cohort risk score and its components...
October 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29229271/using-metabolic-equivalents-in-clinical-practice
#16
REVIEW
Barry A Franklin, Jenna Brinks, Kathy Berra, Carl J Lavie, Neil F Gordon, Laurence S Sperling
Metabolic equivalents, or METs, are routinely employed as a guide to exercise training and activity prescription and to categorize cardiorespiratory fitness (CRF). There are, however, inherent limitations to the concept, as well as common misapplications. CRF and the patient's capacity for physical activity are often overestimated and underestimated, respectively. Moreover, frequently cited fitness thresholds associated with the highest and lowest mortality rates may be misleading, as these are influenced by several factors, including age and gender...
October 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29224709/prevalence-and-prognostic-significance-of-nonsustained-ventricular-tachycardia-in-patients-with-a-left-ventricular-ejection-fraction-from-35-to-50
#17
Sorcha M Allen, Victor A Abrich, Paul S Bibby, Daniel Fishman, Win-Kuang Shen, Dan Sorajja
The risk of life-threatening ventricular arrhythmias in patients with mild-to-moderately reduced left ventricular ejection fraction (LVEF) is unknown. This retrospective case-control study aims to identify the prevalence, risk factors, and outcomes associated with the development of nonsustained ventricular tachycardia (NSVT) as documented on permanent pacemakers or implantable loop recorders in tertiary care center patients with an LVEF of 35% to 50%. Data pertaining to patient demographics, previous medical history, heart failure functional class, echocardiographic parameters, and survival were compared between the groups...
October 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29223289/frequency-and-consequences-of-right-sided-heart-failure-after-continuous-flow-left-ventricular-assist-device-implantation
#18
Chitaru Kurihara, Andre C Critsinelis, Masashi Kawabori, Tadahisa Sugiura, Gabriel Loor, Andrew B Civitello, Jeffrey A Morgan
Postoperative right-sided heart failure (RHF) is a common complication after continuous-flow left ventricular assist device implantation. Studies have examined RHF in the perioperative period, but few have assessed late-onset RHF. We analyzed the incidence of early and late RHF in patients with HeartMate II and HeartWare left ventricular assist devices and associated morbidity, mortality, and independent predictors of RHF. We retrospectively analyzed records of 526 patients with chronic heart failure who underwent continuous-flow left ventricular assist device implantation; 147 (27...
October 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29198986/australian-trends-in-procedural-characteristics-and-outcomes-in-patients-undergoing-percutaneous-coronary-intervention-for-st-elevation-myocardial-infarction
#19
Sinjini Biswas, Stephen J Duffy, Jeffrey Lefkovits, Nick Andrianopoulos, Angela Brennan, Antony Walton, William Chan, Samer Noaman, James A Shaw, Luke Dawson, Andrew Ajani, David J Clark, Melanie Freeman, Chin Hiew, Ernesto Oqueli, Christopher M Reid, Dion Stub
Over the last decade, systems of care for ST-elevation myocardial infarction (STEMI) have evolved to try to improve outcomes and timely access to percutaneous coronary intervention (PCI). There have also been advances in PCI techniques and adjunctive pharmacotherapies. In this study, we sought to determine temporal changes in practices and clinical outcomes of PCI in patients with STEMI. We prospectively collected data on 8,412 consecutive patients undergoing PCI for STEMI between 2005 and 2016 in the multicenter Melbourne Interventional Group registry...
October 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29197471/comparison-of-utilization-trends-indications-and-complications-of-endomyocardial-biopsy-in-native-versus-donor-hearts-from-the-nationwide-inpatient-sample-2002-to-2014
#20
Vikas Singh, Rodrigo Mendirichaga, Ghanshyambhai T Savani, Alex Rodriguez, Vanessa Blumer, Sammy Elmariah, Ignacio Inglessis-Azuaje, Igor Palacios
Native heart endomyocardial biopsy (NH-EMB) is an infrequently performed procedure. The objective of this study is to describe utilization trends, indications, and complications associated with NH-EMB in the United States and compare them with transplanted heart endomyocardial biopsy (TH-EMB). Using the Healthcare Cost and Utilization Project National Inpatient Sample database, we identified 71,105 adult patients undergoing EMB in the inpatient setting in participating hospitals from 2002 to 2014. A total of 20,770 (29%) were performed on NHs (mean age 52...
October 31, 2017: American Journal of Cardiology
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