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Yahya Kemal Icen, Ayse Selcan Koc, Hilmi Erdem Sumbul
The aim of this study was to evaluate the relationship between aortic intima-media thickness (aIMT) and coronary artery disease (CAD) severity in patients with non-ST-segment elevation myocardial infarction (NSTEMI). SYNTAX score (SS) was calculated. Patients were categorized into 2 main groups according to the SS: patient with high risk (SS ≥ 13) and low risk (SS < 13). Common carotid artery IMT (cIMT), common femoral artery IMT, and aIMT were measured with a high-resolution ultrasound Doppler system...
August 16, 2018: Angiology
Pierre Salaun, Ileana Desormais, François-Xavier Lapébie, Alessandra Bura Rivière, Victor Aboyans, Philippe Lacroix, Vincent Bataille, Joël Constans, Carine Boulon Md
The hemodynamic definition of critical limb ischemia (CLI) has evolved over time but remains controversial. We compared the prediction of major amputation by 3 hemodynamic methods. Patients were selected from the Cohorte des Patients ARTériopathes cohort of patients hospitalized for peripheral arterial disease. Patients with CLI were enrolled according to the Trans-Atlantic Inter-Society Consensus Document on Management of Peripheral Arterial Disease II definition and followed up for at least 1 year. We compared the major amputation rate according to initial ankle pressure (AP), systolic toe pressure (STP), and forefoot transcutaneous oxygen pressure (TcPO2 ); 556 patients were included and divided into surgical (264) and medical (292) groups...
August 16, 2018: Angiology
Yasin Ozen, Mustafa Bilal Ozbay, Ahmet Goktuğ Ertem, Çağri Yayla
No abstract text is available yet for this article.
August 16, 2018: Angiology
Koray Demirtas, Çağri Yayla, Ahmet Akdi, Mustafa Karanfil, Mehmet Kadri Akboga, Ahmet Goktuğ Ertem
No abstract text is available yet for this article.
August 14, 2018: Angiology
Ilhan Balamir, Ihsan Ates, Canan Topcuoglu, Turan Turhan
No abstract text is available yet for this article.
August 9, 2018: Angiology
Andrew W Gardner, Polly S Montgomery, Ming Wang, Chixiang Chen, Marcos Kuroki, Danielle Jin-Kwang Kim
We determined whether a greater exercise pressor response during a constant-load treadmill test was associated with lower peak walking time (PWT) and claudication onset time (COT) measured during a graded maximal treadmill test in 304 patients with symptomatic peripheral artery disease (PAD). The exercise pressor response was assessed by measuring heart rate and blood pressure (BP) at rest and during a constant-load treadmill test (speed = 2 mph, grade = 0%). After only 2 minutes of walking, mean heart rate increased by 26 beats/min from rest and mean systolic BP increased by 16 mm Hg...
August 6, 2018: Angiology
Vasiliki Katsi, Georgios Georgiopoulos, Anastasia Skafida, Dimitrios Oikonomou, Dimitrios Klettas, Konstantinos Vemmos, Dimitris Tousoulis
Atrial fibrillation (AF) could be a coincidental finding in certain patients with ischemic stroke and increased burden of underlying cardiovascular disease. Concomitant large-vessel atheromatosis and cerebral small vessel disease may be the actual cause of stroke, and distinguishing between different pathophysiologic mechanisms could impose substantial diagnostic difficulties. Despite routine use of oral anticoagulants (OACs) in patients with AF based on their risk for embolism (ie, CHA2 DS2 -Vasc score), antithrombotic agents may exert differential effects depending on stroke etiology and stroke subtyping should be evaluated as an additional component of risk stratification that could facilitate optimal management...
July 31, 2018: Angiology
Weihong Tang, Lu Yao, Ron C Hoogeveen, Alvaro Alonso, David J Couper, Pamela L Lutsey, Carol C Steenson, Weihua Guan, David W Hunter, Frank A Lederle, Aaron R Folsom
Animal and human laboratory studies suggest that the pathogenesis of abdominal aortic aneurysms (AAAs) involves inflammation and degradation and remodeling of the extracellular matrix. This study prospectively assessed the association between biomarkers for these mechanisms and the presence of AAA during 24 years of follow-up in the Atherosclerosis Risk in Communities (ARIC) study. The ARIC prospectively identified clinically diagnosed AAAs in 15 792 men and women from baseline in 1987 to 1989 to 2011 using hospital discharge codes and death records...
June 26, 2018: Angiology
Niki Katsiki, Vana Kolovou MSc, Aggelos Tsipis Md PhD, Constantinos Mihas Md PhD, Vasiliki Vartela Md, Maria Koutelou Md PhD, Dionisia Manolopoulou, Evangelos Leondiadis Md PhD, Ioannis Iakovou Md PhD, Sophia Mavrogieni Md PhD, Genovefa Kolovou Md PhD
No abstract text is available yet for this article.
September 2018: Angiology
Alexandros A Tzovaras, Fotini Gentimi, Michael Nikolaou
No abstract text is available yet for this article.
September 2018: Angiology
Vana Kolovou, Angelos Tsipis, Constantinos Mihas, Niki Katsiki, Vasiliki Vartela, Maria Koutelou, Dionisia Manolopoulou, Evaggelos Leondiadis, Ioannis Iakovou, Sophie Mavrogieni, Genovefa Kolovou
Patients with left main (LM) coronary artery disease (CAD) are at the highest risk of cardiovascular events. We evaluated possible gene polymorphisms of tumor protein 53 ( TP53, rs1042522, p.Arg72Pro) that can differentiate LM-CAD from patients with more peripheral CAD (MP-CAD) and healthy participants (control group) in 520 individuals (LM-CAD, n = 175; MP-CAD, n = 185; and control group, n = 160). Patients with LM-CAD had the lowest Arg/Arg genotype frequency (36.0%) compared with the MP-CAD (57.3%) and control groups (61...
September 2018: Angiology
Marcus Vinícius Martins Cury, Marcelo Fernando Matielo, Francisco Cardoso Brochado Neto, Rafael de Athayde Soares, Vinícius Lopes Adami, Jalíese Dantas Fernandes Morais, Aline Yoshimi Futigami, Roberto Sacilotto
Intra-arterial digital subtraction angiography (DSA) is commonly used for the diagnosis and treatment of patients with critical limb ischemia (CLI). The aim of this study was to analyze the incidence of contrast-induced nephropathy (CIN) in patients with CLI and to assess their outcomes. Between May 2013 and May 2014, a prospective and observational study was conducted with 107 patients admitted exclusively for CLI treatment. The main outcomes included hemodialysis independence (HI) and overall survival (OS), as assessed by Kaplan-Meier curves...
September 2018: Angiology
Marc Schindewolf, Torsten Fuss, Hanspeter Fink, Armin Gemperli, Axel Haine, Iris Baumgartner
Data on efficacy outcomes of endovascular versus surgical revascularization in patients with critical limb ischemia (CLI) in contemporary practice are limited. In this prospective cohort study, 353 consecutive patients with CLI were enrolled and allocated to endovascular (PTA [percutaneous transluminal angioplasty]), surgical (SURG), or no revascularization (No REVASC) after interdisciplinary consensus. Outcome measures were sustained primary clinical success (sPCS; survival without major amputation, repeated target extremity revascularization, and freedom from CLI), limb salvage, and amputation-free survival...
September 2018: Angiology
Naikuan Fu, Min Liang, Shicheng Yang
The aim of this study is to assess the efficacy of high-dose atorvastatin on the prevention of contrast-induced nephropathy (CIN) in patients with acute coronary syndrome (ACS) undergoing percutaneous intervention and observe the incidence of cystatin C (CyC)-based CIN. A total of 496 patients with ACS were randomly assigned to either the control group (247 patients receiving conventional dose atorvastatin 10 mg daily from 1 day before to 3 days after contrast administration) or the high-dose atorvastatin group (249 patients receiving atorvastatin 40 mg daily for the same perioperative period)...
September 2018: Angiology
Fabien Lareyre, Juliette Raffort, Duy Le, Hon Lai Chan, Thomas Le Houerou, Frédéric Cochennec, Joseph Touma, Pascal Desgranges
The predictive value of the neutrophil to lymphocyte ratio (NLR) has been demonstrated in several cardiovascular diseases. The aim of our study was to investigate the association between the preoperative NLR and aneurysm characteristics as well as 30-day postoperative morbidity and mortality in patients with thoracic aortic aneurysm (TAA) undergoing aortic surgical repair. Consecutive patients (n = 75) with TAA were retrospectively included over a 10-year period. Clinical characteristics, aneurysm characteristics, and 30-day postoperative outcome were recorded...
September 2018: Angiology
Taiwu Lin, Luzhao Wang, Jingbin Guo, Peng Liu, Liheng Chen, Mengqiu Wei, Gongxin Li
The aim of this study was to examine the relationship between low-density lipoprotein cholesterol (LDL-C) and apolipoprotein (Apo) B levels and the SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) score (SS) in patients with stable angina pectoris. We enrolled 594 patients who were suspected to have coronary heart disease (CHD) and who underwent coronary angiography. Patients were divided into 4 groups based on the SS: normal (SS = 0, n = 154), low SS (SS ≤ 22, n = 210), intermediate SS (22 < SS < 32, n = 122), and high SS (SS ≥ 33, n = 63)...
September 2018: Angiology
José Antonio Vargas-Hitos, Alberto Soriano-Maldonado, Josefa Martínez-Bordonado, Isabel Sánchez-Berná, Daniel Fernández-Bergés, José Mario Sabio
Resting heart rate (RHR) is associated with arterial stiffness, inflammation, and cardiovascular (CV) and all-cause mortality in the general population and in patients at high CV risk. We assessed the association of RHR with arterial stiffness and low-grade inflammation (LGI) in a cross-sectional study that included 101 women with systemic lupus erythematosus (SLE) without a history of CV disease or arrhythmia or who were under treatment that may cause bradycardia. Pulse wave velocity (PWV; a measure of arterial stiffness), RHR, and markers of LGI (ie, C-reactive protein, fibrinogen, erythrocyte sedimentation rate, insulin, and homeostatic model assessment index) were measured...
September 2018: Angiology
Nikos Kouvas, Costas Tsioufis, Nikolaos Vogiatzakis, Elias Sanidas, Dimitrios Konstantinidis, Konstantinos Kintis, Kyriakos Dimitriadis, Zoi Kakosaiou, Panagiotis Tsioufis, Mairi Kouremeti, Niki Katsiki, Dimitrios Tousoulis
There is robust evidence from epidemiological and clinical studies showing that elevated heart rate (HR) constitutes a powerful predictor of morbidity and mortality in patients with hypertension, underlining the significance of HR measurement in them. Autonomous nervous system dysfunction and atherosclerosis are important features in the pathogenesis of the untoward events. However, the relationship between HR and blood pressure (BP) is complex and differs depending on the type of BP measurement which is considered...
September 2018: Angiology
Rajat Sharma, Brett Hiebert, David Cheung, Davinder S Jassal, Kunal Minhas
The proportion of individuals >80 years of age constitute an increasing proportion of patients who present with ST-segment elevation myocardial infarction (STEMI). The objective of this study is to evaluate in-hospital outcomes and 1-year survival of very elderly patients who present with an STEMI and undergo primary percutaneous coronary intervention (pPCI). Between 2009 and 2015, individuals >80 years of age (very elderly patients) with an STEMI presenting at a single tertiary Canadian care center were included in the study...
September 2018: Angiology
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