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Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme

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https://www.readbyqxmd.com/read/28934819/the-role-of-gut-hormones-in-diet-induced-weight-change-a-systematic-review
#1
Xue Zhao, Qing Han, Xiaokun Gang, You Lv, Yujia Liu, Chenglin Sun, Guixia Wang
Gut hormones are known to play an important role in long-term weight loss maintenance after bariatric surgery. However, the interplay between gut hormones and diet-induced weight changes remains unclear. Our aims were to evaluate the alterations of gut hormones in diet-induced weight loss, weight maintenance, and weight regain periods. Available studies were searched on MEDLINE, EMASE, ClinicalTrials.gov, the Cochrane Library, and Web of science from inception to October 2016. After selection, 16 studies with 656 participants were included...
September 21, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28934818/effects-of-zinc-alpha2-glycoprotein-on-lipid-metabolism-of-liver-in-high-fat-diet-induced-obese-mice
#2
Guoqiang Fan, Yu Qiao, Shixing Gao, Jun Guo, Ruqian Zhao, Xiaojing Yang
Zinc alpha2 glycoprotein (ZAG) is a new type of adipokine involved in adipose tissue mobilization, however, little is known about its lipid metabolism effect in liver. Therefore, we investigated the effects of ZAG in the regulation of hepatic lipid accumulation. Mice were randomly divided into two groups; one was fed a normal diet and another was fed a high-fat diet for eight weeks to establish obesity model. After that, the normal diet group was divided into ND (injection of pcDNA3.1) and NDZ (injection of ZAG recombinant plasmid) and the high-fat diet group was divided into HF (injection of pcDNA3...
September 21, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28934817/aldosterone-to-renin-ratio-as-a-screening-instrument-for-primary-aldosteronism-in-a-middle-aged-population-with-atrial-fibrillation
#3
Georgios Mourtzinis, Ahmad Ebrahimi, Helena Gustafsson, Gudmundur Johannsson, Karin Manhem
Atrial fibrillation seems to be overrepresented among patients with primary aldosteronism. The aim of this study was to determine the usefulness of aldosterone to renin ratio as a screening instrument for primary aldosteronism in an atrial fibrillation population with relatively low cardiovascular risk profile. A total of 149 patients <65 years and with history of AF were screened for primary aldosteronism using aldosterone to renin ratio. Pathologically increased aldosterone to renin ratio (>65 pmol/mIU) was found in 15 participants (10...
September 21, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28934816/vigorous-physical-activity-is-associated-with-regular-aerobic-exercise-induced-increased-serum-testosterone-levels-in-overweight-obese-men
#4
Hiroshi Kumagai, Toru Yoshikawa, Asako Zempo-Miyaki, Kanae Myoenzono, Takehiko Tsujimoto, Kiyoji Tanaka, Seiji Maeda
Testosterone is a male sex hormone and low circulating testosterone levels are associated with various health disorders in men. Obesity results in reduced circulating testosterone levels in men. Previously, we demonstrated that lifestyle modifications (combination of aerobic exercise and dietary modification) increase circulating testosterone levels in overweight/obese men. However, the effect of regular aerobic exercise on serum testosterone levels remains unclear. The purpose of this study was to investigate the effect of a 12-week aerobic exercise intervention on circulating testosterone levels in normal-weight and overweight/obese men...
September 21, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28931172/the-correlation-between-circulating-betatrophin-and-insulin-resistance-in-general-population-a-meta-analysis
#5
Jinling Xu, Yanyan Lin, Hui Zhou, Linshuang Zhao, Guangda Xiang
Many inconsistent findings are reported on the correlation between circulating betatrophin and insulin resistance in the different population. The aim of this analysis was to explore the correlation between the level of betatrophin and insulin resistance in the general population. The databases of PubMed, EMBASE, and the Cochrane Library (inception to October 26, 2016) were searched without language restrictions for publications that reported studies on associations between betatrophin and insulin resistance in adults...
September 20, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28922680/pivotal-role-of-tnf-%C3%AE-in-the-development-and-progression-of-nonalcoholic-fatty-liver-disease-in-a-murine-model
#6
Satomi Kakino, Tsuyoshi Ohki, Hitomi Nakayama, Xiahong Yuan, Shuichi Otabe, Toshihiko Hashinaga, Nobuhiko Wada, Yayoi Kurita, Kayo Tanaka, Kento Hara, Eri Soejima, Yuji Tajiri, Kentaro Yamada
Previously, we have shown that the adipocyte-specific nuclear form of sterol regulatory element-binding protein-1c (nSREBP-1c) transgenic mice spontaneously developed hepatic lesions that are similar to those of human nonalcoholic steatohepatitis (NASH) with a concomitant elevation of plasma TNF-α. In this study, we analyzed the role of TNF-α in the progression of nonalcoholic fatty liver disease (NAFLD). We established a Tnf knockout nSREBP-1c transgenic mouse line. Glucose tolerance and liver histology were examined at the age of 20 weeks...
September 18, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28922679/impairment-of-gh-igf-1-axis-in-the-liver-of-patients-with-hcv-related-chronic-hepatitis
#7
Simone Carotti, Michele Pier Luca Guarino, Francesco Valentini, Silvio Porzio, Umberto Vespasiani-Gentilucci, Giuseppe Perrone, Maria Zingariello, Paolo Gallo, Michele Cicala, Antonio Picardi, Sergio Morini
No abstract text is available yet for this article.
September 18, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28922678/serum-uric-acid-concentrations-can-predict-hypertension-a-longitudinal-population-based-epidemiological-study
#8
Rongjiong Zheng, Tianmeng Yang, Qingmei Chen, Changxi Chen, Yushan Mao
An elevated serum uric acid concentration may be associated with hypertension, which is the leading cause of death worldwide. However, whether the elevation is causal or a consequence of hypertension among the Chinese population remains unclear. This study was designed to investigate the longitudinal relationship between the serum uric acid concentrations and hypertension among Chinese individuals. This study included 5105 subjects, initially without hypertension, who were followed up for 9 years. The subjects were divided into four groups based on the serum uric acid quartile...
September 18, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28922677/surgery-significantly-improves-neurocognition-sleep-and-blood-pressure-in-primary-hyperparathyroidism-a-3-year-prospective-follow-up-study
#9
Sara Storvall, Eeva M Ryhänen, Ilkka Heiskanen, Harri Sintonen, Risto P Roine, Camilla Schalin-Jäntti
Surgery for primary hyperparathyroidism (PHPT) improves health-related quality of life (HRQoL), but it is unclear whether the effects are sustained after medium-term (>2 years) follow-up, and whether the results on some or all dimensions of HRQoL will reach that of the general population. We performed a follow-up of HRQoL on average 3.3 years after surgery for PHPT using the 15D in our patient cohort (n=124) and compared the results to those of an age- and gender-standardized general population (n=1099)...
September 18, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28922676/combination-therapy-of-intravenous-steroids-and-orbital-irradiation-is-more-effective-than-intravenous-steroids-alone-in-patients-with-graves-orbitopathy
#10
Michael Oeverhaus, Tobias Witteler, Hildegard Lax, Joachim Esser, Dagmar Führer, Anja Eckstein
The aim of this study was to evaluate and compare the efficacy of intravenous (iv) glucocorticoids (GCs) with and without orbital radiotherapy (ORT) in a retrospective analysis of patients with active, moderate-to-severe Graves' orbitopathy (GO). Since diplopia has the strongest impact on quality of life, a careful work up of motility and binocular single vision (BSV) has been performed. The Essen-EUGOGO-Center database (n=3655) was screened for patients with untreated moderate-to-severe, active GO, onset ≤12 months...
September 18, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28922675/clinical-characteristics-and-long-term-outcome-of-primary-aldosteronism-in-a-norwegian-population
#11
Marianne Aardal Grytaas, Siri S Strømsøy, Jarle Tor Rørvik, Jarle Birger Arnes, Anette Heie, Thomas Arnesen, Melissa D Jørstad, Bjørn Gunnar Nedrebø, Dag Erik Jøssang, Dag Kjartan Jensen, Håvard D Rørvik, Jørn Vegard Sagen, Gunnar Mellgren, Hrafnkell B Thordarson, Eystein Sverre Husebye, Kristian Løvås
No abstract text is available yet for this article.
September 18, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28915531/subclinical-hyperthyroidism-and-the-cardiovascular-disease
#12
Alessandro P Delitala
Thyroid hormone excess has complex metabolic effects, particularly on the cardiovascular system. Treatment of these conditions is universally suggested by international guidelines. Subclinical hyperthyroidism, defined by reduced or suppressed TSH levels in the presence of normal free thyroxine and free triiodothyronine values, is common in the general population and progressively increases with aging, being as high as 15.4% in subjects more than 75 years old and more frequent in subjects with nodular goiter...
September 15, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28859208/height-increment-and-laboratory-profile-of-boys-treated-with-aromatase-inhibitors-with-or-without-growth-hormone
#13
Ludmila Fernandes Pedrosa, Joice Marquez de Oliveira, Paula Roberta Vieira Thomé, Cristiane Kochi, Durval Damiani, Carlos Alberto Longui
Aromatase inhibitors (AIs) have been used to recover height loss due to their capacity to delay growth plate closure. Long-term studies describing final heights are needed to determine the efficacy and safety profiles of these drugs for the treatment of impaired growth. This study aims to identify the therapeutic efficiency of AIs in improve growth and to describe potential adverse effects during treatment. Retrospective data analysis of 96 adolescents, among which 22 patients already attained near-final height, were followed at outpatient clinics of two referral centers...
August 31, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28859207/hashimoto-s-thyroiditis-is-an-important-risk-factor-of-papillary-thyroid-microcarcinoma-in-younger-adults
#14
Yujuan Liu, Chengqian Li, Wenjuan Zhao, Yangang Wang
The association between autoimmune thyroid disease and thyroid cancer remains unclear. We performed a matched case-control study to assess the association between Hashimoto's thyroiditis and papillary thyroid microcarcinoma (PTMC). A total of 927 PTMC cases and 927 age- and gender- matched controls selected from the same population were recruited. Odds ratio (OR) with 95% confidence interval (95% CI) was used to assess the strength of the association between Hashimoto's thyroiditis and PTMC. Conditional logistic regression analysis was carried out, and stratified analyses by age, gender and types of thyroid antibodies were also performed...
August 31, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28837972/excessive-catecholamine-secretion-and-the-activation-of-the-renin-angiotensin-aldosterone-system-in-patients-with-pheochromocytoma-a-single-center-experience-and-overview-of-the-literature
#15
Matthias Haase, Till Dringenberg, Stephanie Allelein, Holger S Willenberg, Matthias Schott
Catecholamines stimulate renin-secretion in the juxtaglomerular cells of the kidney and a number of case reports suggest an association between pheochromocytoma and activation of the RAAS. Therefore, it could be asked whether patients suffering from pheochromocytoma with high concentrations of circulating catecholamines present with oversecretion of renin and aldosterone. We identified twelve patients with excessive catecholamine secretion due to pheochromocytoma and compared them to a group of twelve patients with essential hypertension (EH) with regard to the activation of the renin-angiotensin-aldosterone-system (RAAS)...
August 24, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28834963/lipofuscin-accumulation-in-cortisol-producing-adenomas-with-and-without-prkaca-mutations
#16
Anna Angelousi, Eva Szarek, Vincent Shram, Electron Kebebew, Martha Quezado, Constantine A Stratakis
The adrenal cortex accumulates lipofuscin granules with age. Lipofuscin accumulation is also seen in adrenocortical tumors associated with Cushing syndrome (CS), particularly those with PRKAR1A mutations, such as in primary pigmented nodular adrenocortical disease (PPNAD). We investigated the presence of lipofuscin in cortisol-producing adenomas (CPAs) responsible for CS with and without the PRKACA (pLeu206Arg) somatic mutation. Ten paraffin-embedded sections of CPAs from cases with overt CS with (n=4) and without (n=6) a PRKACA mutation were microscopically examined through three detection methods, the hematoxylin-Eosin (H & E) staining, the Fontana Masson (FM) staining using light microscopy, and lipofuscin autofluorescence, using confocal laser scanning microscopy (CLSM)...
August 23, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28768343/correction-maternal-high-fat-diet-during-pregnancy-and-lactation-has-opposite-effects-on-gonadal-expression-of-leptin-and-leptin-receptor-in-rat-dams-and-their-offspring
#17
Agnieszka Rak, Anna Hejmej, Monika Słupecka-Ziemilska, Jaroslaw Woliński, Elzbieta Fiedor, Barbara Bilinska, Ewa Ł Gregoraszczuk
No abstract text is available yet for this article.
August 2, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28768342/correction-the-effects-of-vitamin-d-supplementation-on-glucose-metabolism-and-lipid-profiles-in-patients-with-gestational-diabetes-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#18
Maryam Akbari, Mahmood Moosazadeh, Kamran B Lankarani, Reza Tabrizi, Mansooreh Samimi, Maryam Karamali, Mehri Jamilian, Fariba Kolahdooz, Zatollah Asemi
No abstract text is available yet for this article.
August 2, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28759943/the-effects-of-vitamin-d-supplementation-on-glucose-metabolism-and-lipid-profiles-in-patients-with-gestational-diabetes-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
Maryam Akbari, Mahmood Moosazadeh, Kamran B Lankarani, Reza Tabrizi, Mansooreh Samimi, Maryam Karamali, Mehri Jamilian, Fariba Kolahdooz, Zatollah Asemi
This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to summarize the effect of vitamin D supplementation on glucose homeostasis parameters and lipid profiles in gestational diabetes (GDM) patients. We conducted an electronic systematic search of MEDLINE, and 4 other research databases from inception to August 2016, in addition to performing hand searches and consulting with experts in the field. The index of heterogeneity between studies was determined using Cochran (Q) and I-squared tests...
July 31, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28759942/11-keto-%C3%AE-boswellic-acid-inhibits-lymphocyte-cd3-infiltration-into-pancreatic-islets-of-young-none-obese-diabetic-nod-mice
#20
Ahmed M Shehata, Leticia Quintanilla-Fend, Sabrina Bettio, Zahra Kamyabi-Moghaddam, Ursula A Kohlhofer, Werner A Scherbaum, Hermann P T Ammon
11-Keto-β-Boswellic acid (KBA) has been shown to prevent infiltration of lymphocytes into pancreatic islets and appearance of peri-insular apoptotic cells in an animal model of autoimmune diabetes caused by injection of Multiple Low Doses of Streptozotocin (MLD-STZ), which is a chemical compound belonging to the class of nitrososureas. The aim of this work was to study whether or not KBA can also prevent/attenuate infiltration of lymphocytes into pancreatic islets and appearance of peri-insular apoptotic cells in an animal model of autoimmune diabetes caused by genetic dysfunction resembling human type 1 diabetes in several important features...
July 31, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
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