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Pathology

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https://www.readbyqxmd.com/read/30318165/low-additional-yield-from-prolonged-culture-of-urine-and-differential-detection-of-actinotignum-schaalii-in-a-private-laboratory-setting
#1
LETTER
Benjamin Armstrong, Michael C Wehrhahn
No abstract text is available yet for this article.
October 11, 2018: Pathology
https://www.readbyqxmd.com/read/30314648/a-new-hypoglycaemia-pack-has-revolutionised-hypoglycaemia-investigations-in-infants-and-children
#2
LETTER
Kay Weng Choy
No abstract text is available yet for this article.
October 9, 2018: Pathology
https://www.readbyqxmd.com/read/30314647/combined-hepatocellular-carcinoma-and-high-grade-neuroendocrine-carcinoma-with-ewsr1-gene-rearrangement
#3
LETTER
Khoon Leong Chuah, Brendan Pang, Diana Lim, Chi Kuen Lee, Cora Yuk-Ping Chau
No abstract text is available yet for this article.
October 9, 2018: Pathology
https://www.readbyqxmd.com/read/30314646/adenocarcinoma-ex-goblet-cell-carcinoid-of-the-ascending-colon-concurrent-with-conventional-adenocarcinoma
#4
LETTER
Kyu Yun Jang, Ho Sung Park, Sang Jae Noh, Ho Lee, Min Ro Lee
No abstract text is available yet for this article.
October 9, 2018: Pathology
https://www.readbyqxmd.com/read/30314645/thrombotic-thrombocytopenic-purpura-associated-with-hodgkin-lymphoma-and-non-hodgkin-lymphoma
#5
LETTER
Ross Tomlinson, Julian Yaxley
No abstract text is available yet for this article.
October 9, 2018: Pathology
https://www.readbyqxmd.com/read/30314644/cutaneous-malignant-glomus-tumours-applicability-of-currently-established-malignancy-criteria-for-tumours-occurring-in-the-skin
#6
Boštjan Luzar, Blanca Martin, Cyril Fisher, Eduardo Calonje
Glomus tumours (GTs) have traditionally been classified into benign GTs, GTs with uncertain malignant potential and malignant GTs, based on a combination of criteria such as size of the tumour, degree of nuclear atypia and the level of mitotic activity. Several of the proposed grading criteria are difficult, or even impossible to apply for GTs occurring in the skin. The aim of the study was to analyse the applicability of the currently established GT malignancy criteria for tumours occurring in the skin and to establish their prognostic significance...
October 9, 2018: Pathology
https://www.readbyqxmd.com/read/30314643/unexpected-histological-appearance-of-breast-implant-associated-fibrous-pseudocapsules
#7
LETTER
Mark J Wilsher
No abstract text is available yet for this article.
October 9, 2018: Pathology
https://www.readbyqxmd.com/read/30274817/an-unexpected-diagnosis-leukaemic-presentation-of-blastic-plasmacytoid-dendritic-cell-neoplasm-with-massive-splenomegaly
#8
LETTER
Richard Blennerhassett, Georgia McCaughan, Elizabeth Tegg
No abstract text is available yet for this article.
September 28, 2018: Pathology
https://www.readbyqxmd.com/read/30262185/alk-rearranged-inflammatory-myofibroblastic-tumour-of-placental-membranes
#9
LETTER
Lisa Squires, Admire Matsika, Jessica Turner, Jodie Fitness, Rohan Lourie
No abstract text is available yet for this article.
September 24, 2018: Pathology
https://www.readbyqxmd.com/read/30262184/the-delayed-diagnosis-of-myeloproliferative-neoplasms-is-common-and-results-in-a-high-incidence-of-potentially-preventable-thrombotic-complications
#10
LETTER
Cecily Forsyth, Kathleen Melville, Campbell Tiley
No abstract text is available yet for this article.
September 24, 2018: Pathology
https://www.readbyqxmd.com/read/30262183/comparison-of-the-carbapenem-inactivation-method-cim-and-modified-carbapenem-inactivation-method-mcim-for-the-detection-of-carbapenemase-producing-organisms
#11
LETTER
Amy Crowe, Lisa Brenton, Mikayla Kingston, Darren Jardine, Mary Jo Waters
No abstract text is available yet for this article.
September 24, 2018: Pathology
https://www.readbyqxmd.com/read/30249449/an-undetectable-serum-prealbumin-measurement-led-to-a-diagnosis-of-monoclonal-gammopathy-two-cases-of-spurious-results-in-the-setting-of-paraproteinaemia
#12
LETTER
Kay Weng Choy, Nilika Wijeratne, James Doery, Matthew Lam
No abstract text is available yet for this article.
September 21, 2018: Pathology
https://www.readbyqxmd.com/read/30177220/oral-malignant-gastrointestinal-neuroectodermal-tumour-with-junctional-component-mimicking-mucosal-melanoma
#13
Benjamin M Allanson, Martin A Weber, Louise A Jackett, Charles Chan, Loretta Lau, David S Ziegler, Meera Warby, Chelsea Mayoh, Mark J Cowley, Katherine M Tucker, Georgina V Long, Annabelle Maher, Antoinette Anazodo, Richard A Scolyer
Malignant gastrointestinal neuroectodermal tumour (GNET) is a recently characterised rare and aggressive tumour that typically arises in association with the small intestine of adults. We present a novel case of this entity and expand the spectrum of its reported morphological features. The patient was a 5-year-old female, the youngest reported patient affected by the condition, and presented with extra-abdominal disease. The histopathological features included the presence of a junctional component of the palatal tumour, which mimicked mucosal melanoma, a feature that has not been previously reported in GNET...
August 31, 2018: Pathology
https://www.readbyqxmd.com/read/30177219/vitamin-c-deficiency-in-an-australian-cohort-of-metropolitan-surgical-patients
#14
Praveen Ravindran, Stephanie Wiltshire, Kamalakanta Das, Robert B Wilson
Vitamin C is an essential micronutrient in the human diet. While large population studies measuring vitamin C have been performed in other countries, there are few studies of deficiency in the Australian population. This study aimed to quantify vitamin C deficiency, identify scorbutic symptoms and examine dietary associations in a cohort of preoperative general surgical patients. Vitamin C levels were determined in a cohort of patients referred to a single surgeon between January 2011 and December 2013. Baseline data were collected along with data on fruit consumption, weekly citrus fruit intake and presence of scorbutic symptoms...
August 31, 2018: Pathology
https://www.readbyqxmd.com/read/30170702/pleural-malignant-mesothelioma-versus-pleuropulmonary-synovial-sarcoma-a-clinicopathological-study-of-22-cases-with-molecular-analysis-and-survival-data
#15
Sonja Klebe, Sarita Prabhakaran, Ashleigh Hocking, Emily Pulford, Sarah Moore, Mario Nicola, Philip W Allen, Douglas W Henderson
The aim of this study was to carry out a comparative analysis by transducin-like enhancer of split 1 (TLE1) immunohistochemistry and molecular analysis of SYT-SSX, for 16 pleural predominantly sarcomatoid mesotheliomas and six cases of pleuropulmonary synovial sarcoma (five pleural in distribution only, with one case of a predominantly subpleural upper lobe synovial sarcoma), all of which were solely or predominantly monophasic. Our comparison included survival and some clinical data. We consider that the following points emerged from this study...
August 28, 2018: Pathology
https://www.readbyqxmd.com/read/30166125/immunological-environment-in-colorectal-cancer-a-computer-aided-morphometric-study-of-whole-slide-digital-images-derived-from-tissue-microarray
#16
Daniel Eyraud, Benjamin Granger, Armelle Bardier, Yann Loncar, GaËlle Gottrand, Gilles Le Naour, Jean-Michel Siksik, Jean-Christophe Vaillant, David Klatzmann, Louis Puybasset, Frederic Charlotte, Jeremy Augustin
Cancer research has moved from investigating tumour cells to including analysis of the tumour microenvironment as well. The aim of this study was to assess the cellular infiltrate of colorectal cancer (CRC) using computer-aided analysis of whole slide digital image derived from tissue microarray (TMA). TMA slides from 31 CRC patients were immunostained for forkhead box protein 3 (FOXP3) and immunomodulatory enzyme indoleamine 2,3-dioxygenase (IDO) at four sites: centre (C) and invasive front (F) of the tumour, proximal non-metastatic draining lymph node (N-), tumour-draining lymph node with metastasis (N+) and healthy mucosa at 10 cm from the cancer (M)...
August 27, 2018: Pathology
https://www.readbyqxmd.com/read/30149993/competing-risks-analysis-of-the-effect-of-local-residual-tumour-on-recurrence-and-cancer-specific-death-after-resection-of-colorectal-cancer-implications-for-staging
#17
Ronald C Newland, Charles Chan, Pierre H Chapuis, Anil Keshava, Matthew J F X Rickard, Christopher J Young, Owen F Dent
The pTNM staging system for colorectal cancer (CRC) is not entirely effective in discriminating between potentially curative and non-curative resections because it does not account for local residual tumour in patients with stages I, II or III. This study aimed to evaluate the prognostic importance of histologically verified tumour in any line of resection of the bowel resection specimen (TLR) in relation to pTNM stages and to demonstrate how TLR may be integrated into pTNM staging. Information on patients in the period 1995 to 2010 with complete follow-up to the end of 2015 was extracted from a prospective database of CRC resections...
August 24, 2018: Pathology
https://www.readbyqxmd.com/read/30149992/downregulation-of-dhrs9-is-associated-with-poor-prognosis-in-oral-squamous-cell-carcinoma
#18
Hiroyuki Shimomura, Tomonori Sasahira, Chie Nakashima, Miyako Shimomura-Kurihara, Tadaaki Kirita
Oral squamous cell carcinoma (OSCC) has a high potential for local invasion and nodal metastasis. Therefore, early detection and elucidation of the detailed molecular mechanisms underlying OSCC are essential. Dehydrogenase/reductase member 9 (DHRS9) is downregulated in recurrent OSCC. Although DHRS9 is reported to act as a tumour suppressor in several malignancies, its expression in OSCC cells is unknown. In this study, we examined DHRS9 expression immunohistochemically in specimens from a sample of 98 OSCC patients...
August 24, 2018: Pathology
https://www.readbyqxmd.com/read/30149991/multiple-endocrine-neoplasia-type-1-clinical-correlates-of-men1-gene-methylation
#19
Ricardo De Paoli-Iseppi, Louise Prentice, James R Marthick, Russell Thomson, Adele F Holloway, Joanne L Dickinson, John Burgess
Multiple endocrine neoplasia type 1 (MEN 1) has marked severity variation between individuals with the same mutation. To investigate any relationship between promoter methylation and clinical features, blood and tissue samples were collected from 16 members of the Tasman 1 MEN 1 kindred carrying a common splice site mutation and 7 patients with sporadic MEN 1. Methylation at 39 CpGs in the MEN1 promoter were assessed in formalin fixed, paraffin embedded parathyroid tissue. Clinical disease severity markers included age at first parathyroid operation, parathyroid hormone level and corrected serum calcium levels...
August 24, 2018: Pathology
https://www.readbyqxmd.com/read/30149990/expression-of-ccl21-by-ebv-associated-gastric-carcinoma-cells-protects-cd8-ccr7-t-lymphocytes-from-apoptosis-via-the-mitochondria-mediated-pathway
#20
Fang Tang, Jian-Ning Chen, Na-Na Zhang, Li-Ping Gong, Ye Jiang, Zhi-Ying Feng, Lin Xiao, Hai-Gang Li, Hong Du, Bin Wu, Chun-Kui Shao
About 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV), which are defined as EBV-associated gastric carcinomas (EBVaGCs). EBVaGCs are usually accompanied by massive lymphocytes infiltration, among which CD8+ T cells are predominant. To date, the apoptosis of the infiltrating CD8+ T cells in EBVaGC has not been investigated. In the present study, we assessed the immunophenotype and apoptosis of tumour infiltrating lymphocytes (TILs) in both EBVaGC and EBV-negative gastric carcinoma (EBVnGC)...
August 24, 2018: Pathology
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