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Pathology

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https://www.readbyqxmd.com/read/28705348/-aussie-normals-an-a-priori-study-to-develop-reference-intervals-in-a-healthy-australian-population-using-the-beckman-coulter-lh-750-haematology-analyser-as-candidates-for-harmonised-values
#1
G Koerbin, J M Potter, K Andriolo, N P West, N Glasgow, C Hawkins, J A Cavanaugh, P E Hickman
Reference limits or intervals are important benchmarks or tools that help the clinician to distinguish between a result that is most likely to lie within a 'healthy' or diseased category. It has been suggested that a review of haematology reference intervals is long overdue. In this study we report on our findings for analytes routinely measured in a complete blood count (CBC) performed on the Beckman Coulter LH 750 analyser and an additional comparative study using the Beckman Coulter LH 750, the Sysmex XN and Abbott Sapphire...
July 10, 2017: Pathology
https://www.readbyqxmd.com/read/28705347/loss-of-bap1-expression-is-very-rare-in-breast-carcinoma
#2
LETTER
Jeanie Chui, Arjun Singh, Anthony J Gill
No abstract text is available yet for this article.
July 10, 2017: Pathology
https://www.readbyqxmd.com/read/28693750/idelalisib-induced-cmv-gastrointestinal-disease-the-need-for-vigilance-with-novel-therapies
#3
LETTER
Lorena Goldring, Beena Kumar, T Eng Gan, Michael Sze Yuan Low
No abstract text is available yet for this article.
July 7, 2017: Pathology
https://www.readbyqxmd.com/read/28693749/primary-gastrointestinal-anaplastic-large-cell-lymphoma
#4
Yi-Ying Lee, Katsuyoshi Takata, Ren-Ching Wang, Sheau-Fang Yang, Shih-Sung Chuang
Primary gastrointestinal anaplastic large cell lymphoma (GI-ALCL) is rare. We report eight new cases. The median age was 61.5 years (range 10-88), most frequently involving the stomach (n = 3) and small intestine (n = 4). The neoplastic hallmark cells in all cases expressed CD30. Anaplastic lymphoma kinase (ALK) protein was expressed in two cases (25%). By in situ hybridisation, all cases were negative for Epstein-Barr virus and for DUSP22/IRF4 gene translocation. At a median follow-up time of 37.5 months, four patients died of disease, one was alive with disease, and three were disease-free...
July 7, 2017: Pathology
https://www.readbyqxmd.com/read/28693748/mixed-mucinous-adenocarcinoma-and-somatostatinoma-of-the-ampulla-of-vater-associated-with-neurofibromatosis-type-1
#5
LETTER
Róisín Reynolds, Veli Marjoniemi
No abstract text is available yet for this article.
July 7, 2017: Pathology
https://www.readbyqxmd.com/read/28693747/germline-bap1-mutations-also-predispose-to-cutaneous-squamous-cell-carcinoma
#6
LETTER
Robert V Rawson, Geoffrey F Watson, Annabelle M Maher, Stanley W McCarthy, John F Thompson, Richard A Scolyer
No abstract text is available yet for this article.
July 7, 2017: Pathology
https://www.readbyqxmd.com/read/28689635/extrauterine-peritoneal-placental-site-nodule
#7
LETTER
Caroline Kurek, Richard Jaworski, Vince Lamaro
No abstract text is available yet for this article.
July 6, 2017: Pathology
https://www.readbyqxmd.com/read/28689634/impact-of-the-australian-gender-specific-thresholds-using-the-abbott-high-sensitivity-troponin-i-assay-in-clinical-care
#8
Robert Bender, Faith Njue, Samuel Vasikaran, Ramon Lambert, Jamie Rankin, Graham S Hillis, Damon A Bell
The aim of this study was to ascertain the impact of gender specific hs-TnI thresholds in a clinical setting and determine the clinical characteristics and discharge diagnosis for individuals presenting to the Emergency Department (ED) with elevated troponin I with the Abbott high-sensitivity troponin I (hs-TnI) assay, but non-elevated troponin I on the previous generation assay (STAT TnI-II). Medical records of individuals presenting to the Royal Perth Hospital ED with elevated hs-TnI between 12 November 2013 and 24 December 2013 were retrospectively reviewed...
July 6, 2017: Pathology
https://www.readbyqxmd.com/read/28689633/follicular-lymphoma-with-hyaline-vascular-castleman-disease-like-follicles-and-cd20-positive-follicular-dendritic-cells
#9
LETTER
Sergio Pina-Oviedo, Wei Wang, Erin Vicknair, John T Manning, L Jeffrey Medeiros
No abstract text is available yet for this article.
July 6, 2017: Pathology
https://www.readbyqxmd.com/read/28689632/foreign-body-ileitis-a-histopathological-mimic-of-crohn-s-disease
#10
LETTER
Sailakshmi Krishnan, Tony Dill, David Simons, Hui Yin
No abstract text is available yet for this article.
July 6, 2017: Pathology
https://www.readbyqxmd.com/read/28689631/vasculogenic-mimicry-in%C3%A2-vitro-in-tumour-cells-derived-from-metastatic-malignant-pleural-effusions
#11
LETTER
Francesca Sasanelli, Ashleigh Hocking, Emily Pulford, Yazad Irani, Sonja Klebe
No abstract text is available yet for this article.
July 6, 2017: Pathology
https://www.readbyqxmd.com/read/28688724/pd-1-and-pd-l1-expression-in-bone-and-soft-tissue-sarcomas
#12
Alireza Torabi, Clarissa N Amaya, Frank H Wians, Brad A Bryan
PD-1 and its ligands have been shown to play a significant role in evasion of malignant tumour cells from the immune system. Last year, the Unites States Food and Drug Administration (FDA) approved anti-PD-1 inhibitors for treatment of non-small cell lung carcinoma and recently expanded the use of immunotherapy for metastatic urothelial cell carcinoma and Hodgkin lymphoma. However, studies on expression of PD-1 and its ligand in malignant bone and soft tissue sarcoma are sparse. In this study, we evaluated PD-1 and PD-L1 expression on variants of liposarcomas and rhabdomyosarcomas, osteosarcomas and chondrosarcomas...
July 5, 2017: Pathology
https://www.readbyqxmd.com/read/28673429/a-novel-fibrinogen-gamma-chain-mutation-c-1096c-g-p-his340asp-fibrinogen-ankara-causing-hypofibrinogenaemia-and-hepatic-storage
#13
LETTER
Francesco Callea, Isabella Giovannoni, Sinan Sari, Aysel Unlusoy Aksu, Guldal Esendagly, Buket Dalgic, Renata Boldrini, Gulen Akyol, Paola Francalanci, Emanuele Bellacchio
No abstract text is available yet for this article.
June 30, 2017: Pathology
https://www.readbyqxmd.com/read/28673428/indolent-t-cell-lymphoproliferative-disease-of-the-gastrointestinal-tract-in-a-renal-transplant-patient-diagnostic-pitfalls-and-clinical-challenges
#14
LETTER
https://www.readbyqxmd.com/read/28673427/linear-variant-of-large-plaque-type-blue-naevus-with-subcutaneous-cellular-nodules
#15
LETTER
Cyril Habougit, Dominique Michiels-Marzais, Qing Wang, Daniel Pissaloux, Arnaud de la Fouchardiere
No abstract text is available yet for this article.
June 30, 2017: Pathology
https://www.readbyqxmd.com/read/28669579/lessons-learnt-from-implementation-of-a-lynch-syndrome-screening-program-for-patients-with-gynaecological-malignancy
#16
Fedaa Najdawi, Ashley Crook, Jayne Maidens, Christopher McEvoy, Andrew Fellowes, Justine Pickett, Musei Ho, David Nevell, Kirsten McIlroy, Amy Sheen, Loretta Sioson, Mahsa Ahadi, John Turchini, Adele Clarkson, Russell Hogg, Sue Valmadre, Greg Gard, Susan J Dooley, Rodney J Scott, Stephen B Fox, Michael Field, Anthony J Gill
Despite a trend towards universal testing, best practice to screen patients presenting with gynaecological malignancy for Lynch syndrome (LS) is uncertain. We report our institutional experience of a co-ordinated gynaecological LS screening program. All patients with endometrial carcinoma or carcinosarcoma, or gynaecological endometrioid or clear cell carcinomas undergo reflex four panel immunohistochemistry (IHC) for MLH1, PMS2, MSH2 and MSH6 followed by cascade somatic hypermethylation analysis of the MLH1 promoter locus for dual MLH1/PMS2 negative tumours...
June 29, 2017: Pathology
https://www.readbyqxmd.com/read/28669578/prognostic-evaluation-of-alip-and-cd34-immunostaining-in-ipss-r-subgroups-of-myelodysplastic-syndromes
#17
Bei Xiong, Yanbo Nie, Zehai Tang, Mei Xue, Xuelan Zuo
In order to evaluate the prognostic value of abnormal localisation of immature precursors (ALIP) and CD34 immunostaining in myelodysplastic syndromes (MDS), bone marrow histopathological features in 187 MDS patients were retrospectively analysed and the prognostic significance of ALIP and CD34 immunostaining on overall survival (OS) and progression to leukaemia-free survival (PFS) in total patients and different Revised-International Prognostic Scoring System (IPSS-R) subgroups were evaluated. In univariate analysis, age ≥60, ALIP, ≥5% CD34+ cells, CD34+ clusters and IPSS-R subgroups were associated with shorter OS (p = 0...
June 29, 2017: Pathology
https://www.readbyqxmd.com/read/28668174/paraneoplastic-thrombocytosis-is-associated-with-increased-mortality-and-increased-rate-of-lymph-node-metastasis-in-oesophageal-adenocarcinoma
#18
Agoston T Agoston, Amitabh Srivastava, Yifan Zheng, Raphael Bueno, Robert D Odze, Zoltan Szallasi
Paraneoplastic thrombocytosis has been associated with adverse outcomes in several cancers, but has not been described in oesophageal adenocarcinoma. The aim of our study was to examine the prognostic value of platelet counts in patients with oesophageal adenocarcinoma. A cohort of 584 patients who underwent oesophagectomy for oesophageal adenocarcinoma was identified. Platelet counts, history of neoadjuvant chemoradiation, and clinicopathological factors such as T and N stage, and overall survival were recorded...
June 28, 2017: Pathology
https://www.readbyqxmd.com/read/28666644/response-to-absence-of-gnas-and-braf-mutations-but-presence-of-kras-mutation-in-urachal-adenocarcinoma-author-reply
#19
LETTER
Jen-Fan Hang, Chin-Chen Pan
No abstract text is available yet for this article.
June 28, 2017: Pathology
https://www.readbyqxmd.com/read/28666640/extremely-low-high-density-lipoprotein-cholesterol-hdl-in-a-patient-with-diffuse-b-cell-lymphoma
#20
LETTER
Tze Ping Loh, Michelle Poon, Gloria Hui Jia Chan, Sunil Kumar Sethi, Alvin Wong
No abstract text is available yet for this article.
June 28, 2017: Pathology
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