journal
MENU ▼
Read by QxMD icon Read
search

Pathology

journal
https://www.readbyqxmd.com/read/30503217/htlv-1-is-rare-in-far-north-queensland-despite-a-significant-burden-of-classically-associated-diseases
#1
Simon Smith, Darren Russell, Peter Horne, Josh Hanson
Human T-lymphotropic virus type 1 (HTLV-1) is hyperendemic amongst Indigenous Australians living in Central Australia. The epidemiology of the disease is poorly defined in other parts of Australia, despite a high prevalence of classically associated conditions. All HTLV-1 serology tests requested through public health facilities in Far North Queensland (FNQ) from January 1999 to December 2016 were reviewed. The person's age, sex, ethnicity, location, rationale for testing and result were recorded. There were 444 tests performed in 409 people; 217 (53%) were male; 171 (42%) identified as Indigenous Australians...
November 28, 2018: Pathology
https://www.readbyqxmd.com/read/30503216/lower-number-of-5-hydroxymethylcytosine-expressing-cells-in-plasma-cell-myeloma-than-in-reactive-plasma-cell-hyperplasia-a-useful-immunohistochemical-approach-for-identification-of-neoplastic-plasma-cells
#2
Maki Ohya, Koh Nakazawa, Hiroyuki Kanno
Plasma cell myeloma (PCM) is a haematological malignancy defined by aberrant proliferation of plasma cells in the bone marrow. For the diagnosis of PCM, immunostaining of light chains or surface marker analyses by flow cytometry is needed but sometimes difficult. Aberrant methylation at the carbon-5 position of cytosine results in 5-methylcytosine (5-mC), which is a well-known epigenetic hallmark of cancer in mammals. 5-mC is oxidised to 5-hydroxymethylcytosine (5-hmC), and low 5-hmC levels occur in several cancers and haematopoietic malignancies...
November 28, 2018: Pathology
https://www.readbyqxmd.com/read/30502217/mismatch-repair-deficiency-is-implicated-in-carcinoma-arising-from-ovarian-teratoma
#3
Alvin Ho-Kwan Cheung, Chit Chow, Mei-Yung Yu, Wendy Wai-Tak Law, Peggy Pui-Ying Law, Paul Cheung-Lung Choi, Wei Kang, Ka-Fai To
Malignant transformation of benign mature ovarian teratoma can result in a wide spectrum of cancer, including a variety of carcinoma, sarcoma, or melanoma. The role of mismatch repair defects in such malignant transformation is still elusive. In view of current immunotherapy, the role of mismatch repair deficiency can have significant implications on therapeutic strategy. Thus, we aimed to investigate the possible involvement of mismatch repair deficiency in somatic-type carcinoma arising from teratoma. We examined seven cases of malignant transformation of ovarian teratoma to carcinoma from the years 2000-2017...
November 27, 2018: Pathology
https://www.readbyqxmd.com/read/30497805/mmp-9-1562-c-t-single-nucleotide-polymorphism-associates-with-increased-mmp-9-level-and-activity-during-papillary-thyroid-carcinoma-progression
#4
Jelena Roncevic, Ilona Djoric, Sonja Selemetjev, Jelena Jankovic, Tijana Isic Dencic, Vesna Bozic, Dubravka Cvejic
Papillary thyroid carcinoma (PTC), a common form of thyroid malignancy, displays significant variations in clinical features and outcome. The malignant transformation of the thyroid is driven by altered expression of many matrix-modulating enzymes, including matrix metalloproteinase-9 (MMP-9). A single nucleotide polymorphism in its promotor (-1562 C/T) is suspected to cause overexpression of MMP-9, which in turn contributes to development of a tumour unfavourable phenotype. The aim of this study was to investigate the impact of MMP-9 promotor genotype on MMP-9 expression in PTC samples, and to assess its value as a possible risk factor for developing PTC or its aggressive phenotype...
November 26, 2018: Pathology
https://www.readbyqxmd.com/read/30497804/maternally-expressed-paternally-imprinted-embryonic-non-coding-rna-are-expressed-in-osteosarcoma-ewing-sarcoma-and-spindle-cell-sarcoma
#5
LETTER
Darrell Green, Archana Singh, Jasmine Sanghera, Lee Jeys, Vaiyapuri Sumathi, Tamas Dalmay, William D Fraser
No abstract text is available yet for this article.
November 26, 2018: Pathology
https://www.readbyqxmd.com/read/30497803/mmr-protein-immunohistochemistry-and-microsatellite-instability-in-gastric-cancers
#6
LETTER
Junhun Cho, So Young Kang, Kyoung-Mee Kim
No abstract text is available yet for this article.
November 26, 2018: Pathology
https://www.readbyqxmd.com/read/30497802/a-high-seroprevalence-of-human-herpesvirus-type-8-already-present-in-patients-with-chronic-hepatitis-before-the-development-of-cirrhosis
#7
Jen-Pi Tsai, Kuo-Chih Tseng, Ming-Nan Lin, Cheng-Chuan Su
A high seroprevalence of human herpesvirus type 8 (HHV-8) in mild cirrhotics is significantly associated with hepatitis activity. Cirrhosis is always derived from chronic hepatitis. We aimed to evaluate the prevalence of HHV-8 infection in patients with chronic hepatitis. Blood samples collected from 129 patients with chronic hepatitis and 129 age- and sex-matched healthy controls were analysed for monocyte and platelet counts, hepatitis B surface antigen (HBsAg), anti-hepatitis C virus (anti-HCV), HHV-8 antibody and DNA, and alanine aminotransferase (ALT)...
November 26, 2018: Pathology
https://www.readbyqxmd.com/read/30497801/primary-anorectal-melanoma-clinical-immunohistology-and-dna-analysis-of-43-cases
#8
Tristan J Dodds, James S Wilmott, Louise A Jackett, Serigne N Lo, Georgina V Long, John F Thompson, Richard A Scolyer
Primary melanoma involving the anorectal region is rare, accounting for <1% of all melanomas in most Western countries. It characteristically presents at an advanced clinical stage and is associated with poor clinical outcomes. Preliminary reports suggest that response rates to immunotherapies in patients with advanced stage mucosal melanoma are much lower than in cutaneous (or acral) melanoma patients but reasons for this are unclear. Comprehensive characterisation of the immune microenvironment in anorectal melanoma has not previously been performed...
November 26, 2018: Pathology
https://www.readbyqxmd.com/read/30482401/blastic-plasmacytoid-dendritic-cell-neoplasm-with-immunoblastoid-morphology-and-myc-rearrangement-and-overexpression
#9
LETTER
Kung-Chao Chang, Julia Yu-Yun Lee, Kana Sakamoto, Satoko Baba, Kengo Takeuchi
No abstract text is available yet for this article.
November 24, 2018: Pathology
https://www.readbyqxmd.com/read/30482400/acute-epstein-barr-virus-hepatitis-superimposed-on-drug-induced-liver-injury-causing-severe-hepatic-dysfunction
#10
LETTER
Samuel Foong, Stella Pendle, Raymond Kwok, Sebastianus Kwon, Raghu Gill, Ronald Tomlins, Sandra O'Toole
No abstract text is available yet for this article.
November 24, 2018: Pathology
https://www.readbyqxmd.com/read/30477881/approximately-1-of-chronic-myeloid-leukaemia-cases-present-with-isolated-thrombocytosis-and-express-common-major-breakpoints-a-finding-from-a-laboratory-audit
#11
LETTER
Teng Fong Ng, Matthew Wright, Rebecca De Kraa
No abstract text is available yet for this article.
November 24, 2018: Pathology
https://www.readbyqxmd.com/read/30477884/chronic-kidney-cortical-damage-is-associated-with-baseline-kidney-function-and-albuminuria-in-patients-managed-with-radical-nephrectomy-for-kidney-tumours
#12
Robert J Ellis, Benjamin Kalma, Sharon J Del Vecchio, Danielle N Aliano, Keng Lim Ng, Goce Dimeski, Li Ma, David Guard, John F Bertram, Christudas Morais, Kimberley Oliver, Simon T Wood, Glenda C Gobe, Ross S Francis
This study evaluated the relationship between histological markers of chronic kidney damage in patients undergoing radical nephrectomy for kidney tumours and preoperative kidney function, degree of albuminuria, and changes in glomerular volume. A schema to grade chronic kidney damage could be used to identify patients at risk of developing CKD following nephrectomy. Non-neoplastic cortical tissue was sourced from 150 patients undergoing radical nephrectomy for suspected kidney cancer. This tissue was evaluated for indicators of chronic damage, specifically: glomerulosclerosis, arteriosclerosis, interstitial fibrosis, and tubular atrophy...
November 23, 2018: Pathology
https://www.readbyqxmd.com/read/30477883/rhabdomyosarcoma-with-fus-re-arrangement-additional-case-in-support-of-a-novel-subtype
#13
LETTER
Daniel D Wong, Chris van Vliet, Andrew Gaman, Tindaro Giardina, Benhur Amanuel
No abstract text is available yet for this article.
November 23, 2018: Pathology
https://www.readbyqxmd.com/read/30477882/dataset-for-the-reporting-of-prostate-carcinoma-in-core-needle-biopsy-and-transurethral-resection-and-enucleation-specimens-recommendations-from-the-international-collaboration-on-cancer-reporting-iccr
#14
Lars Egevad, Meagan Judge, Brett Delahunt, Peter A Humphrey, Glen Kristiansen, Jon Oxley, Krishan Rasiah, Hiroyuki Takahashi, Kiril Trpkov, Murali Varma, Thomas M Wheeler, Ming Zhou, John R Srigley, James G Kench
The International Collaboration on Cancer Reporting (ICCR) is a project which issues datasets and guidelines for international standardisation of cancer reporting. This review summarises the required and recommended elements of the datasets for prostate core needle biopsies and transurethral resection (TURP) and enucleation specimens of the prostate. To obtain as much information as possible from needle biopsies there should be only one core in each specimen jar with the exception of saturation biopsies. The gross description of the specimens should include core lengths of needle biopsies and weight of resection specimens...
November 23, 2018: Pathology
https://www.readbyqxmd.com/read/30477880/high-reproducibility-is-attainable-in-assessing-histoprognostic-parameters-of-pt1-colorectal-cancer-using-routine-histopathology-slides-and-immunohistochemistry-analyses
#15
Fanny Barel, Anaïs Auffret, Mélanie Cariou, Tiphaine Kermarrec, Laura Samaison, Amélie Bourhis, Bogdan Badic, Julien Jézéquel, Franck Cholet, Jean-Pierre Bail, Pascale Marcorelles, Jean-Baptiste Nousbaum, Michel Robaszkiewicz, Laurent Doucet, Arnaud Uguen
Assessment of the risk of lymph node invasion and tumour recurrence is critical to determine whether additional surgery is required in patients with endoscopically-removed pT1 colorectal cancer (CRC). A reproducible assessment of this risk of recurrence based on histopathological parameters is crucial for relevant therapeutic decisions. The inter-observer reproducibility of these parameters was the subject of our study. Two pathologists independently analysed 163 endoscopically-removed pT1 CRC recorded in a local digestive cancer registry database (Finistère, France)...
November 23, 2018: Pathology
https://www.readbyqxmd.com/read/30477879/ectopic-cervical-well-differentiated-thymic-carcinoma-report-of-a-diagnostically-challenging-rare-case
#16
LETTER
Giap Hean Goh, Fei Fan Wang, Kwok Seng Loh, Fredrik Petersson
No abstract text is available yet for this article.
November 23, 2018: Pathology
https://www.readbyqxmd.com/read/30473182/overexpression-of-cdk7-is-associated-with-unfavourable-prognosis-in-oral-squamous-cell-carcinoma
#17
Lei Jiang, Rong Huang, Yaping Wu, Pengfei Diao, Wei Zhang, Jin Li, Zhongwu Li, Yanling Wang, Jie Cheng, Jianrong Yang
Increased expression of cyclin-dependent kinase 7 (CDK7), an ubiquitous kinase associated with cell cycle and transcription, contributes to human tumourigenesis and associates with patients' prognosis. In the present study, we sought to investigate the expression pattern of CDK7 and its clinicopathological significance in primary oral squamous cell carcinoma (OSCC). The expression of CDK7 mRNA in OSCC was determined by data mining and interrogation using the Oncomine database. Its protein expression was measured by immunohistochemistry in clinical samples from a retrospective cohort of 113 patients with primary OSCC which were treated at our institution from January 2006 to December 2016...
November 22, 2018: Pathology
https://www.readbyqxmd.com/read/30471841/fdg-pet-ct-findings-the-vital-clue-to-rare-diagnosis-of-herpes-simplex-virus-lymphadenitis-simulating-richter-transformation
#18
LETTER
Abby P Douglas, Mohammad Atarod, H Miles Prince
No abstract text is available yet for this article.
November 22, 2018: Pathology
https://www.readbyqxmd.com/read/30471840/uterine-intravascular-adenomyomatosis-a-bizarre-hybrid-lesion
#19
LETTER
Amir Maghsoudi, Jennifer Roberts, Peter Russell
No abstract text is available yet for this article.
November 22, 2018: Pathology
https://www.readbyqxmd.com/read/30470411/analysis-of-chromosome-12p-over-representation-and-clinicopathological-features-in-mediastinal-teratomas
#20
Taebum Lee, Youjeong Seo, Joungho Han, Ghee Young Kwon
Teratomas show diverse biologic behaviour and prognosis as well as variable histological features. Importantly, post-pubertal testicular teratomas composed of mature components have a potential for malignant behaviour, in contrast to ovarian dermoid cysts and pre-pubertal testicular teratomas which are considered almost always benign. On the other hand, the biological behaviour and histogenesis of extragonadal teratomas are still not fully elucidated. In this study of mediastinal mature teratoma (MT), we investigated clinicopathological features and chromosome 12 short arm (12p) status which constitutes a major genetic aberration in the germ cell tumours (GCT) and is indicative of malignant potential...
November 20, 2018: Pathology
journal
journal
22087
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"