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Pathology

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https://www.readbyqxmd.com/read/29910046/spontaneous-breast-haematoma-in-a-woman-with-bernard-soulier-giant-platelet-disorder
#1
LETTER
Badr AbdullGaffar, Lakshmiah Raman
No abstract text is available yet for this article.
June 14, 2018: Pathology
https://www.readbyqxmd.com/read/29908842/indolent-primary-cutaneous-cd8-positive-t-cell-lymphoid-proliferations
#2
LETTER
Yalda Hakemi, John Pyne, Anita Muljono, Esther Myint
No abstract text is available yet for this article.
June 13, 2018: Pathology
https://www.readbyqxmd.com/read/29908841/neuroendocrine-cells-associated-with-endocrine-mucin-producing-sweat-gland-carcinoma-a-potential-precursor-lesion
#3
LETTER
Tomonori Kawasaki, Toshinobu Kubota, Shu Ichihara, Keizo Horibe, Takahiro Hasebe
No abstract text is available yet for this article.
June 13, 2018: Pathology
https://www.readbyqxmd.com/read/29891191/clofazimine-drug-susceptibility-testing-for-mycobacterium-tuberculosis-the-case-of-using-the-right-diluent
#4
Li-Hwei Sng, Justine Woei Ling Peh, Melody Tai Lee Kee, Nurhazirah Bte Mohd Ya'akob, Rick Twee-Hee Ong, Christopher W Wong, Cynthia Bin Eng Chee, Yee Tang Wang
Accurate and reliable drug susceptibility testing (DST) is essential for the effective treatment and control of tuberculosis. With the increase in drug-resistant organisms, newer and less conventional antimicrobial agents are used for treatment. Recently, we found an unprecedented rise in the number of clofazimine-resistant Mycobacterium tuberculosis isolates in our laboratory. An investigation found that this phenomenon was due to a change in the method of drug preparation. We performed studies to assess the impact of water and dimethyl sulfoxide (DMSO) as a final diluent for clofazimine drug testing...
June 8, 2018: Pathology
https://www.readbyqxmd.com/read/29891190/overexpression-of-homer2-predicts-better-outcome-in-low-grade-endometrioid-endometrial-adenocarcinoma
#5
Paulette Mhawech-Fauceglia, Saloni Walia, Annie Yessaian, Hiroko Machida, Koji Matsuo, Kate Lawrenson
We have previously shown that HOMER2 (Homer scaffolding protein 2), a protein coding gene, was highly expressed in low grade (LG) endometrioid adenocarcinoma (EAC) of the uterus. The role of HOMER2 in endometrial cancer (EC) is widely unknown; therefore, the aim of this study was to determine the expression and the predictive value of HOMER2 protein expression in series of patients with EC. HOMER2 protein expression was detected on paraffin-embedded tissues from 336 cases using immunohistochemistry (IHC). Tumours were categorised in two groups; group 1 (EAC, FIGO grade 1 and 2; n = 191) and group 2 (all other subtypes including grade 3 EAC; n = 145)...
June 8, 2018: Pathology
https://www.readbyqxmd.com/read/29891189/aldh1a1-positive-cells-are-a-unique-component-of-the-tonsillar-crypt-niche-and-are-lost-along-with-ngfr-positive-stem-cells-during-tumourigenesis
#6
Vivian Wu, Megan Auchman, Peter A Mollica, Patrick C Sachs, Robert D Bruno
Interest into the cellular biology of human tonsillar crypts has grown in recent years because it is now known to be the site of origin of most human papilloma virus (HPV) induced oropharyngeal squamous cell carcinomas (OPSCC). Despite the interest, still relatively little is known regarding the cellular hierarchy and dynamics of this anatomical subsite. Here we evaluate normal tonsillar crypts for expression of putative stem cell markers. We found that ALDH1A1 was uniquely expressed in a subset of suprabasal tonsillar crypt epithelium...
June 8, 2018: Pathology
https://www.readbyqxmd.com/read/29773325/urea-another-analyte-recommended-for-harmonised-reference-intervals
#7
LETTER
G Koerbin, K Sikaris, G R D Jones, J R Tate
No abstract text is available yet for this article.
May 14, 2018: Pathology
https://www.readbyqxmd.com/read/29752126/simultaneous-co-detection-of-wild-type-and-vaccine-strain-measles-virus-using-the-bd-max-system
#8
Kiran Thapa, Justin A Ellem, Kerri Basile, Ian Carter, Tom Olma, Sharon C-A Chen, Dominic E Dwyer, Jen Kok
Despite the reported elimination of measles virus in Australia, importation of cases from endemic countries continues to lead to secondary local transmission and outbreaks. Rapid laboratory confirmation of measles is paramount for individual patient management and outbreak responses. Further, it is important to rapidly distinguish infection from wild-type virus or vaccine strains to guide public health responses. We developed a high throughput, TaqMan-based multiplex reverse-transcription-polymerase chain reaction (PCR) assay using the BD MAX platform (Becton Dickinson) that simultaneously detects measles virus and differentiates between wild-type and vaccine strains without the need for sequencing...
May 8, 2018: Pathology
https://www.readbyqxmd.com/read/29743145/cic-rearranged-sarcoma-of-the-pleura-an-unreported-primary-site-expanding-the-anatomical-distribution-of-an-emerging-entity
#9
LETTER
Lisa Wilkinson, John Coucher, Michelle Murphy, Warren Joubert, Caroline Cooper
No abstract text is available yet for this article.
May 7, 2018: Pathology
https://www.readbyqxmd.com/read/29743144/a-simple-kaolin-clotting-time-confirm-ratio-for-the-presence-of-a-lupus-anticoagulant
#10
LETTER
Vaughan K Williams
No abstract text is available yet for this article.
May 7, 2018: Pathology
https://www.readbyqxmd.com/read/29743143/the-wilms-tumour-1-gene-as-a-factor-in-non-syndromic-hypospadias-evidence-and-controversy
#11
REVIEW
Gergely Buglyó, Dániel Beyer, Sándor Biró, Éva Oláh
Hypospadias is one of the most frequent congenital anomalies of the male external genitalia. Its pathogenesis is due to largely unknown or poorly understood genetic factors and is further complicated by environmental-intrauterine-risk factors. One of the genes currently in focus by molecular biologists and clinicians studying syndromic forms of hypospadias is the Wilms' tumour 1 (WT1) gene. There is controversy over whether WT1 defects are also responsible for isolated hypospadias. In this review, we briefly cover the role of WT1 as a transcription factor and discuss proposed pathogenic pathways leading to hypospadias, outlining possible directions for research...
May 7, 2018: Pathology
https://www.readbyqxmd.com/read/29743142/evaluation-of-p16-protein-expression-and-cdkn2a-deletion-in-conventional-and-fibrosarcomatous-dermatofibrosarcoma-protuberans
#12
LETTER
Andrew Siref, Vatsal Patel, John D Reith, Bonnie L Balzer, Wonwoo Shon
No abstract text is available yet for this article.
May 7, 2018: Pathology
https://www.readbyqxmd.com/read/29739616/schistosoma-egg-induced-liver-pathology-resolution-by-sm-p80-based-schistosomiasis-vaccine-in-baboons
#13
Loc Le, Adebayo J Molehin, Stewart Nash, Souad R Sennoune, Gul Ahmad, Workineh Torben, Weidong Zhang, Afzal A Siddiqui
Schistosomiasis remains a serious chronic debilitating hepato-intestinal disease. Current control measures based on mass drug administration are inadequate due to sustained re-infection rates, low treatment coverage and emergence of drug resistance. Hence, there is an urgent need for a schistosomiasis vaccine for disease control. In this study, we assessed the anti-pathology efficacy of Schistosoma mansoni large subunit of calpain (Sm-p80)-based vaccine against schistosomiasis caused by infections with Schistosoma mansoni in baboons...
May 5, 2018: Pathology
https://www.readbyqxmd.com/read/29739615/mucosal-schwann-cell-hamartoma-of-gall-bladder-a-novel-observation
#14
LETTER
Gaurav Khanna, Shouriyo Ghosh, Adarsh Barwad, Rajni Yadav, Prasenjit Das
No abstract text is available yet for this article.
May 5, 2018: Pathology
https://www.readbyqxmd.com/read/29735170/ipilimumab-and-nivolumab-associated-enterocolitis-with-florid-necrotising-granulomatous-inflammation-a-novel-manifestation-of-immunomodulatory-enterocolitis
#15
LETTER
David J W Paton, Lydia Warburton, Kim Chung, Tarek M Meniawy, M Priyanthi Kumarasinghe
No abstract text is available yet for this article.
May 4, 2018: Pathology
https://www.readbyqxmd.com/read/29735169/subungual-acantholytic-dyskeratotic-acanthoma-an-unusual-cause-of-longitudinal-erythronychia
#16
LETTER
Jeremy Ng, Nathan Tobias Harvey, Jamie von Nida, Benjamin Andrew Wood
No abstract text is available yet for this article.
May 4, 2018: Pathology
https://www.readbyqxmd.com/read/29735168/image-analysis-of-fibrosis-in-labial-salivary-glands-of-patients-with-systemic-autoimmune-diseases-close-correlation-of-lobular-fibrosis-to-seropositive-rheumatoid-arthritis-and-increased-anti-ccp-and-rf-titres-in-the-serum
#17
Krisztián Katona, Nelli Farkas, Mária Kneif, Gábor SütŐ, Tímea Berki, Balázs Balatonyi, Tamás Tornóczky
Lobular fibrosis in labial salivary glands of patients with systemic autoimmune disease is a rarely examined and rather neglected histological change. Its significance and disease association is poorly understood. Our aim was to explore the clinical correlations of fibrosis in labial salivary gland samples using objective methods and laboratory parameters. Labial salivary gland samples from more than 300 patients over a 3-year period were selected from the archives of the pathology department, histologically examined, digitised, image analysed and statistically evaluated to identify the presence and intensity of lobular fibrosis, its relation to age, clinical diagnoses of systemic autoimmune disease and the presence of rheumatoid factor (RF), anti-cyclic citrullinated peptide (CCP), antinuclear antibodies (ANAs), and anti-dsDNA serum markers...
May 4, 2018: Pathology
https://www.readbyqxmd.com/read/29731144/immunohistochemical-expression-of-somatostatin-receptors-sstr2a-and-sstr5-in-299-pituitary-adenomas
#18
LETTER
Talia L Fuchs, Loretta Sioson, Amy Sheen, Adele Clarkson, Anthony J Gill
No abstract text is available yet for this article.
May 3, 2018: Pathology
https://www.readbyqxmd.com/read/29731143/liver-ectopic-pregnancy-complicating-a-focal-nodular-hyperplasia
#19
LETTER
Georgia Karpathiou, Radwan Kassir, Sid Ali Berremila, Florian Camy, Michel Peoc'h
No abstract text is available yet for this article.
May 3, 2018: Pathology
https://www.readbyqxmd.com/read/29731142/concurrent-mycobacterium-tuberculosis-infection-and-nodal-marginal-zone-lymphoma
#20
LETTER
Aditya Tedjaseputra, Beena Kumar, Sabine de Silva, Stephen Opat
No abstract text is available yet for this article.
May 3, 2018: Pathology
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