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European Neurology

Evangelos Anagnostou, Evangelia Kararizou, Ioannis Evdokimidis
No abstract text is available yet for this article.
December 2, 2016: European Neurology
Thibault Moreau, Catherine Bungener, Olivier Heinzlef, Laurent Suchet, Florent Borgel, Isabelle Bourdeix, Mohamed Meite, Karin Rerat, Isabelle Chouette
The objective of this prospective study was to assess the changes in anxiety levels, and their relationship with coping strategies over the first four months of fingolimod treatment in patients with relapsing remitting multiple sclerosis (RRMS). Data were collected at the inclusion visit (Visit 1) and 4 months later (Visit 2). We used the Hospital Anxiety and Depression Scale (HADS) to assess the level of anxiety and the Coping Inventory for Stressful Situations scale to assess the coping strategies used when engaged with stressful situations...
December 2, 2016: European Neurology
Bruno Niemeyer, Renato Niemeyer, Rafael Borges, Edson Marchiori
No abstract text is available yet for this article.
November 29, 2016: European Neurology
Tomoe Sato, Maho Shiobara, Masatoyo Nishizawa, Takayoshi Shimohata
INTRODUCTION: The importance of nutritional management in neurodegenerative diseases is increasingly recognized in the clinical setting. However, few reports have examined the nutritional intake in patients with multiple system atrophy (MSA). Here, we investigated changes in daily caloric intake, body mass index (BMI) and nutritional status during the disease course of MSA. METHODS: We performed a single-hospital study of 82 consecutive patients with probable MSA according to the consensus criteria...
November 29, 2016: European Neurology
Chloé Laurencin, Anne Sophie Brunet, Jérôme Dumortier, Laurence Lion-Francois, Stéphane Thobois, Jean Yves Mabrut, Rémi Dubois, France Woimant, Aurélia Poujois, Olivier Guillaud, Alain Lachaux, Emmanuel Broussolle
BACKGROUND: The aim of this work is to report our early experiences about the benefits of liver transplantation (LT) in the treatment of persistent neurological symptoms in Wilson's disease (WD) patients. METHODS: We describe our findings in 4 WD patients with neurological impairment or symptoms treated by LT: 2 patients had transplants due to worsening of neurological symptoms despite long-term appropriate medical treatment. The other 2 required LT because of symptoms associated with liver failure...
November 19, 2016: European Neurology
Dorothea Mair, Monika Huegens-Penzel, Wolfram Kress, Christian Roth, Andreas Ferbert
BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) presents with 2 genetically distinct types. We describe for the first time the MRI patterns of leg muscle involvement in type 2 and compare it with type 1. METHODS: The intramuscular fat content was assessed on lower extremity axial T1-weighted MRI scans in 6 FSHD1 and 5 FSHD2 patients. RESULTS: Overall, the muscle involvement profile did not differ substantially between FSHD1 and FSHD2...
November 18, 2016: European Neurology
Jialan Sun, Fenghua Sun, Kang Yang, Ningzhen Fu, Longxuan Li
BACKGROUND: Atherosclerosis is a complicated disease governed by genetic, environmental and vascular risk factors, while its relationship with specific genes is still unclear. In recent days, it has been discovered that the single-nucleotide polymorphisms of chromosomal region 9p21 were relevant with the genetic susceptibility of Atherosclerosis. We aimed to figure out the relativity between the gene polymorphism of region 9p21 (rs10757274, rs7044859, rs4977574 and rs496892) and carotid plaque...
November 16, 2016: European Neurology
Daphne van der Willik, Nadine Pelzer, Ale Algra, Gisela M Terwindt, Marieke J H Wermer
BACKGROUND: To investigate the connection between migraine and stroke, a reliable screening tool to gather information about a person's migraine history is crucial. We studied the test-characteristics of a 5-question Migraine Screener for Stroke (MISS). METHODS: We included a random sample of patients with a transient ischemic attack or stroke who answered the MISS questionnaire when they were admitted to our hospital. After discharge, a semi-structured telephone interview was conducted to validate the migraine diagnosis with the International Classification of Headache Disorders, second-edition criteria as gold standard...
November 11, 2016: European Neurology
John M S Pearce
This historical essay outlines early ideas and clinical accounts of hysteria. It reproduces verbatim parts of a remarkable text of Thomas Sydenham. This provides the most detailed description of hysterical symptoms, contemporary treatment and particularly Sydenham's opinions about the nature of the disorder. His portrayal is compared to later and modern concepts and classification.
September 23, 2016: European Neurology
Salvatore Caratozzolo, Stefano Gipponi, Alessandra Marengoni, Elisa Pari, Andrea Scalvini, Luca Pasina, Mauro Magoni, Alessandro Padovani
BACKGROUND: Polypharmacy is very common in older persons and it is associated with inappropriate prescribing and potential drug-drug interactions (DDIs). Aims of this study were to identify prevalence of DDIs in older persons with acute stroke and to evaluate the association between stroke and DDIs. METHODS: One hundred forty-six patients admitted with diagnosis of acute stroke were enrolled. The therapeutic regimen of patients was analyzed at admission to identify the number of DDIs, prevalence and sorts of serious DDIs according to subtype of acute stroke (ischemic or hemorrhagic) and to its recurrence...
September 9, 2016: European Neurology
Ugur Uygunoglu, Aysegul Gunduz, Melih Tutuncu, Mehmet Ali Akalin, Sabahattin Saip, Aksel Siva
No abstract text is available yet for this article.
September 9, 2016: European Neurology
Hui Zhang, Zhuqin Gu, Liang Sun, Ming Cao, Dawei Li, Jinghong Ma, Piu Chan
AIMS: To confirm whether the presence and/or timing of rapid eye movement sleep behavior disorder (RBD) onset were associated with differences in clinical features of Parkinson's disease (PD), clinical characteristics of PD patients with RBD occurring before and after PD diagnosis were investigated. METHODS: Consecutive PD patients were enrolled between July 2011 and February 2012. RBD questionnaire Hong Kong and clinical interviews were used to identify RBD symptoms and onsets...
September 9, 2016: European Neurology
Soo Jin Yoon, Jae Guk Kim
No abstract text is available yet for this article.
September 7, 2016: European Neurology
Maud Ranchet, Emmanuel Broussolle, Laurence Paire-Ficout
BACKGROUND/AIMS: (1) To investigate how specific executive functions change over 2 years in drivers with Parkinson's disease (PD) compared to controls, using both neuropsychological and driving simulator tasks; and (2) to explore the association between the decline of specific executive functions and changes in driving habits in PD. METHODS: Sixteen PD patients and 21 controls underwent neuropsychological testing twice and performed tasks on a driving simulator, with an interval of approximately 2 years...
September 2, 2016: European Neurology
Csilla Vér, Miklós Emri, Tamás Spisák, Ervin Berényi, Kázmér Kovács, Péter Katona, László Balkay, László Menyhárt, László Kardos, László Csiba
BACKGROUND: This study aims at investigating the short-term efficacy of the continuous passive motion (CPM) device developed for the therapy of ankle-foot paresis and to investigate by fMRI the blood oxygen level-dependent responses (BOLD) during ankle passive movement (PM). METHODS: Sixty-four stroke patients were investigated. Patients were assigned into 2 groups: 49 patients received both 15 min manual and 30 min device therapy (M + D), while the other group (n = 15) received only 15 min manual therapy (M)...
August 31, 2016: European Neurology
Benoit Delpont, Corine Aboa-Eboulé, Jérôme Durier, Jean-Michel Petit, Anaïs Daumas, Nicolas Legris, Benoit Daubail, Maurice Giroud, Yannick Béjot
We aimed to investigate associations between serum thyroid stimulating hormone (TSH) levels and both severity and outcome after ischemic stroke (IS). A total of 731 patients consecutive IS patients were enrolled (mean age 69.4 ± 15.4, 61.6% men), and serum TSH levels were measured at admission and analyzed according to the tertiles of their distribution (<0.822 vs. 0.822-1.6 vs. >1.6 mUI/l). Associations between TSH and both severity at admission (National Institutes of Health Stroke Scale (NIHSS) scores <5 vs...
August 27, 2016: European Neurology
Yassar Alamri, Michael MacAskill, Tim Anderson
No abstract text is available yet for this article.
August 25, 2016: European Neurology
Ki-Woong Nam, Jae-Sung Lim, Dong-Wan Kang, Yong-Seok Lee, Moon-Ku Han, Hyung-Min Kwon
OBJECTIVE: Pontine infarction is a common type of brain stem infarction and early neurological deterioration (END). We evaluated the possibility of severe white matter hyperintensity (WMH) as a predictor of END in isolated pontine infarction. METHODS: We recruited 2 types of patients with isolated pontine infarction within 24 h from symptom onset. END was defined as an increase of ≥1 point on the motor National Institutes of Health Stroke Scale (NIHSS) or ≥2 points on the total NIHSS score within 72 h from admission...
August 18, 2016: European Neurology
Oscar H Del Brutto, Robertino M Mera, Mauricio Zambrano
BACKGROUND: The association between edentulism and cerebral small vessel disease is controversial. We aimed to assess this relationship in community-dwelling older adults living in rural Ecuador. METHODS: MRI was performed in 311 (81%) of 385 individuals ≥60 years enrolled in the Atahualpa Project. Participants were classified in 2 groups according to whether they have severe edentulism (<10 remaining teeth) or not. Using multivariate logistic regression and exposure effect models, we assessed whether edentulism correlated with severity of white matter hyperintensities (WMHs), after adjusting for relevant confounders...
August 17, 2016: European Neurology
Koji Tanaka, Takeshi Yamada, Takako Torii, Shoji Matsumoto, Takeo Yoshimura, Kei-Ichiro Takase, Yoshifumi Wakata, Naoki Nakashima, Jun-Ichi Kira, Hiroyuki Murai
BACKGROUND: We aimed to determine the predictive factors for excellent or extremely poor functional outcome in patients with first-ever atrial fibrillation (AF)-related cardioembolic stroke. METHODS: Retrospective observational study from a database. Patients with AF-related cardioembolic stroke with a premorbid modified Rankin Scale (mRS) score of 0 or 1 and without a previous history of stroke were included. RESULTS: Factors associated with excellent functional outcome (mRS scores of 0 or 1; n = 77; 30...
August 11, 2016: European Neurology
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