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European Neurology

Sang Hun Lee, Seung Chai Jung, Dong Wha Kang, Sun U Kwon, Jong S Kim
BACKGROUND: The stroke mechanism for anterolateral pontine infarction (ALPI) is poorly understood. We aimed to investigate the perforator arteries relevant to ALPI using high-resolution MRI (HR-MRI). METHODS: Of 62 patients with ALPI who were admitted to the Asan Medical Center, 13 patients agreed to participate in this study. We used HR-MRI with a 3-Tesla scanner and assessed the perforating branches directly connected with the infarcted area. RESULTS: Perforating arteries penetrating ALPI were identified in all 13 patients...
September 19, 2017: European Neurology
Lazaros C Triarhou
The article is a 75-year memorial tribute to the Greek neurologist, Constantin Tsiminakis (1875-1942). Coming from a family of physicians, Tsiminakis graduated from the University of Athens in 1897, and trained in Vienna under Nothnagel, Frankl-Hochwart, and Obersteiner. In 1905, he was appointed Reader in Neurology and Psychiatry at his alma mater. He published over 40 articles on topics of neurology and neuropathology, including megalencephaly, hydrocephalus, progressive paralysis, epidemic encephalitis, dengue fever, and narcolepsy...
2017: European Neurology
Oscar H Del Brutto, Robertino M Mera, Aldo F Costa, Victor J Del Brutto
BACKGROUND: The relationship between basilar artery (BA) diameter and Circle of Willis (CoW) configuration has been scarcely investigated. We aimed to assess this association in community-dwelling older adults. METHODS: MRAs of 346 individuals were reviewed. Using generalized linear models adjusted for demographics and cardiovascular risk factors, we assessed the relationship between BA diameter and fetal and non-fetal types CoW, as well as the impact of this relationship on BA ectasia prevalence...
2017: European Neurology
Yerim Kim, Dae Young Yoon, Jee-Eun Kim, Kang Min Park, Ju-Hun Lee, Hong-Ki Song, Jong Seok Bae
BACKGROUND: Stroke is a disastrous disease and a major health burden worldwide, especially in Korea. Hemorrhagic stroke (HS) accounts for approximately 20% of all the types of strokes. It is important to be able to evaluate stroke diagnoses and evolving treatments. OBJECTIVE: We aimed to identify the top-100 cited articles and assess a paradigm shift that occurred in the field of HS. METHODS: We searched all articles that had been cited more than 100 times using the Web of Science citation search tool during January 2016...
2017: European Neurology
Yong Huang, Zuowei Wang, Zan Chen, Hao Wu, Fengzeng Jian
OBJECTIVE: It is difficult to completely and safely remove a tumor that is located in the subaxial cervical spine by using the posterior approach because of the anatomical characteristics. Previous reports regarding the total removal of subaxial schwannomas using the one-stage posterior approach are still limited. This study was to evaluate the feasibility and efficacy of treating the dumbbell-shaped schwannomas in the subaxial cervical spine using the one-stage posterior approach. METHODS: Patients with dumbbell-shaped schwannomas in the subaxial cervical spine were treated using the one-stage posterior approach...
2017: European Neurology
John M S Pearce
In the well-known story of the illness of King George III, what is often overlooked is the part played by Dr. Francis Willis, an inconspicuous doctor who with great success ran an asylum in Lincolnshire. In November 1788, he was called to attend the King whose mania was becoming uncontrollable. Because of his interventions there was a slow but marked improvement. The King's recovery in 1789 increased Willis' reputation and expanded his practice.
2017: European Neurology
Ling-Yan Ma, Xiao-Dan Chen, Yong He, Hui-Zi Ma, Tao Feng
BACKGROUND/AIMS: The topological organization of brain functional networks is impaired in Parkinson's disease (PD). However, the altered patterns of functional network hubs in different subtypes of PD are not completely understood. METHODS: 3T resting-state functional MRI and voxel-based graph-theory analysis were employed to systematically investigate the intrinsic functional connectivity patterns of whole-brain networks. We enrolled 31 patients with PD (12 tremor dominant [TD] and 19 with postural instability/gait difficulty [PIGD]) and 22 matched healthy controls...
2017: European Neurology
Juliane Dunkel, Christian Roth, Frank Erbguth, Wenke Dietrich, Monika Hügens-Penzel, Andreas Ferbert
OBJECTIVE: Symptomatic cerebral fat embolism (CFE) is a rare complication that occurs after a traumatic injury or orthopaedic surgery and is diagnostically challenging. No data is currently available concerning long-term follow-up. METHODS: We identified from medical records 9 patients with CFE and revised the clinical signs and the diagnostic process. We then analysed long-term follow-up data, targeting clinical course after discharge, neurological impairment, and current quality of life, using the Barthel index and the modified Rankin Scale...
2017: European Neurology
Alla A Vein
The sculpture of the devil on a portal of the Lichtenthal Abbey School in Baden-Baden, Germany displays neurological pathology, possibly consistent with multiple cranial neuropathy. One of the main abnormalities is an exotropia strabismus, a feature rarely depicted in works of art portraying the devil.
2017: European Neurology
Qi-Yu Chen, Xiao-Rui Zhu, Yu Zhang
The study explored hemodynamic changes in patients with cerebral arteriovenous malformations (CAVM) before and -after interventional embolization therapy with Glubran 2 acrylic glue and analyzed the related factors. CAVM patients received endovascular embolization therapy with Glubran 2. Patients' systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), blood flow velocity (BFV), and pulsatility index (PI) were measured. The location of malformed vessels, Spetzler-Martin (SM) grade, CAVM size, and type of feeding artery and venous drainage were analyzed...
2017: European Neurology
Takeo Sato, Yuka Terasawa, Hidetaka Mitsumura, Teppei Komatsu, Kenichi Sakuta, Kenichiro Sakai, Satoshi Matsushima, Yasuyuki Iguchi
BACKGROUND/AIMS: The factors related to cerebrovascular complications in cerebral venous sinus thrombosis (CVST) are controversial. We focused on venous stasis and investigated its relationship with cerebrovascular complications in CVST. METHODS: CVST patients between June 2013 and October 2016 were enrolled. Relationships between cerebrovascular complications, defined as cerebral venous infarction, intracerebral hemorrhage, or subarachnoid hemorrhage, and cerebrum venous stasis and other clinical information were retrospectively analyzed...
2017: European Neurology
Hiroyuki Neishi, Masamichi Ikawa, Hidehiko Okazawa, Tetsuya Tsujikawa, Hidetaka Arishima, Ken-Ichiro Kikuta, Makoto Yoneda
BACKGROUND: This study sought to precisely evaluate striatal oxidative stress and its relationship with the disease severity in Parkinson's disease (PD) using double brain imaging, 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) (62Cu-ATSM) PET and 123I-FP-CIT SPECT. METHODS: Nine PD patients were studied with brain 62Cu-ATSM PET for oxidative stress and 123I-FP-CIT SPECT for the density of striatal dopamine transporter. Standardized uptake values (SUVs) were obtained from the delayed phase of dynamic 62Cu-ATSM PET, and striatum-to-cerebellum SUV ratio (SUVR) was calculated...
2017: European Neurology
Jia Li, Zhiwei Lou, Xiaoyang Liu, Yajuan Sun, Jiajun Chen
AIMS: To assess the efficacy and safety of adjuvant treatment with entacapone in the treatment of later Parkinson's disease (PD) patients with motor fluctuation. METHODS: We conducted a systematic review of relevant studies from 8 databases to June 23, 2016. RESULTS: Fourteen studies were included in this review (n = 2,804). The results showed that compared with placebo, adjuvant therapy with entacapone significantly increased on time (p < 0...
2017: European Neurology
Ozlem Gungor-Tuncer, Vuslat Yilmaz, Alper Toker, Guher Saruhan-Direskeneli, Yesim Gulsen-Parman, Piraye Oflazer-Serdaroglu, Feza Deymeer
BACKGROUND: The difficult course of patients with myasthenia gravis (MG) with anti-muscle-specific tyrosine kinase antibodies (MuSK) has been emphasized. However, no clear information is available on patients who have a benign course. METHODS: This study was aimed at comparing patients with favorable (minimal manifestations [MM] or better) and unfavorable outcomes to determine whether excellent response to corticosteroid (CS) treatment within 3 months (good response-3 months) has any predictive effect on the prognosis...
2017: European Neurology
Burcu Zeydan, Ugur Uygunoglu, Ayse Altintas, Sabahattin Saip, Aksel Siva, Truus E M Abbink, Marjo S van der Knaap, Cengiz Yalcinkaya
No abstract text is available yet for this article.
2017: European Neurology
Dirk Enders, Monika Balzer-Geldsetzer, Oliver Riedel, Richard Dodel, Hans-Ulrich Wittchen, Sven-Christian Sensken, Björn Wolff, Jens-Peter Reese
BACKGROUND: Epidemiological data on the prevalence of Parkinson's disease (PD) in Germany are limited. The aims of this study were to estimate the age- and gender-specific prevalence of PD in Germany as well as the severity and illness duration. SUMMARY: A systematic literature search was performed in 5 different databases. European studies were included if they reported age- and gender-specific numbers of prevalence rates of PD. Meta-analytic approaches were applied to derive age- and gender-specific pooled prevalence estimates...
2017: European Neurology
Seung Ha Lee, Chul Hyoung Lyoo, Hanna Cho, Juha O Rinne, Myung Sik Lee
OBJECTIVE: To define the significance of striatal cribriform state (SCS) observed in patients with primary progressive parkinsonism. METHODS: We reviewed medical records and brain magnetic resonance imaging studies of 1,260 patients with primary progressive parkinsonism. We identified 23 patients with SCS and analyzed their clinical features. RESULTS: All 23 patients had rapidly progressive parkinsonism predominated by postural instability and gait disturbance...
2017: European Neurology
(no author information available yet)
No abstract text is available yet for this article.
2017: European Neurology
(no author information available yet)
No abstract text is available yet for this article.
2017: European Neurology
Yun Jing, Xinxin Liu, Lei Yu, Ran Li
AIMS: To compare the long-term outcomes of non-thymomatous myasthenia gravis (MG) patients receiving pre-thymectomy (Pre-CS) or post-thymectomy corticosteroid (Post-CS) therapy. METHODS: In a retrospective cohort study, 41 patients with MG were treated with Pre-CS therapy, and 110 were treated with Post-CS therapy. RESULTS: In the MG cohorts, 9 of 40 patients (22.5%) in the Pre-CS group vs. 28 of 105 patients (26.7%) in the Post-CS group achieved a complete remission (CR) at 1 year, 29...
2017: European Neurology
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