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European Neurology

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https://www.readbyqxmd.com/read/28813703/efficacy-and-safety-of-adjuvant-treatment-with-entacapone-in-advanced-parkinson-s-disease-with-motor-fluctuation-a-systematic-meta-analysis
#1
Jia Li, Zhiwei Lou, Xiaoyang Liu, Yajuan Sun, Jiajun Chen
AIMS: To assess the efficacy and safety of adjuvant treatment with entacapone in the treatment of later Parkinson's disease (PD) patients with motor fluctuation. METHODS: We conducted a systematic review of relevant studies from 8 databases to June 23, 2016. RESULTS: Fourteen studies were included in this review (n = 2,804). The results showed that compared with placebo, adjuvant therapy with entacapone significantly increased on time (p < 0...
August 16, 2017: European Neurology
https://www.readbyqxmd.com/read/28768265/prompt-response-to-prednisone-predicts-benign-course-in-musk-mg
#2
Ozlem Gungor-Tuncer, Vuslat Yilmaz, Alper Toker, Guher Saruhan-Direskeneli, Yesim Gulsen-Parman, Piraye Oflazer-Serdaroglu, Feza Deymeer
BACKGROUND: The difficult course of patients with myasthenia gravis (MG) with anti-muscle-specific tyrosine kinase antibodies (MuSK) has been emphasized. However, no clear information is available on patients who have a benign course. METHODS: This study was aimed at comparing patients with favorable (minimal manifestations [MM] or better) and unfavorable outcomes to determine whether excellent response to corticosteroid (CS) treatment within 3 months (good response-3 months) has any predictive effect on the prognosis...
July 28, 2017: European Neurology
https://www.readbyqxmd.com/read/28746937/prevalence-duration-and-severity-of-parkinson-s-disease-in-germany-a-combined-meta-analysis-from-literature-data-and-outpatient-samples
#3
Dirk Enders, Monika Balzer-Geldsetzer, Oliver Riedel, Richard Dodel, Hans-Ulrich Wittchen, Sven-Christian Sensken, Björn Wolff, Jens-Peter Reese
BACKGROUND: Epidemiological data on the prevalence of Parkinson's disease (PD) in Germany are limited. The aims of this study were to estimate the age- and gender-specific prevalence of PD in Germany as well as the severity and illness duration. SUMMARY: A systematic literature search was performed in 5 different databases. European studies were included if they reported age- and gender-specific numbers of prevalence rates of PD. Meta-analytic approaches were applied to derive age- and gender-specific pooled prevalence estimates...
July 27, 2017: European Neurology
https://www.readbyqxmd.com/read/28746943/identification-of-3-novel-patients-with-clcn2-related-leukoencephalopathy-due-to-clcn2-mutations
#4
Burcu Zeydan, Ugur Uygunoglu, Ayse Altintas, Sabahattin Saip, Aksel Siva, Truus E M Abbink, Marjo S van der Knaap, Cengiz Yalcinkaya
No abstract text is available yet for this article.
July 26, 2017: European Neurology
https://www.readbyqxmd.com/read/28746923/parkinsonian-patients-with-striatal-cribriform-state-present-rapidly-progressive-axial-parkinsonism
#5
Seung Ha Lee, Chul Hyoung Lyoo, Hanna Cho, Juha O Rinne, Myung Sik Lee
OBJECTIVE: To define the significance of striatal cribriform state (SCS) observed in patients with primary progressive parkinsonism. METHODS: We reviewed medical records and brain magnetic resonance imaging studies of 1,260 patients with primary progressive parkinsonism. We identified 23 patients with SCS and analyzed their clinical features. RESULTS: All 23 patients had rapidly progressive parkinsonism predominated by postural instability and gait disturbance...
July 26, 2017: European Neurology
https://www.readbyqxmd.com/read/28743123/erratum
#6
(no author information available yet)
No abstract text is available yet for this article.
2017: European Neurology
https://www.readbyqxmd.com/read/28743117/erratum
#7
(no author information available yet)
No abstract text is available yet for this article.
2017: European Neurology
https://www.readbyqxmd.com/read/28738395/outcomes-of-preoperative-and-postoperative-corticosteroid-therapies-in-myasthenia-gravis
#8
Yun Jing, Xinxin Liu, Lei Yu, Ran Li
AIMS: To compare the long-term outcomes of non-thymomatous myasthenia gravis (MG) patients receiving pre-thymectomy (Pre-CS) or post-thymectomy corticosteroid (Post-CS) therapy. METHODS: In a retrospective cohort study, 41 patients with MG were treated with Pre-CS therapy, and 110 were treated with Post-CS therapy. RESULTS: In the MG cohorts, 9 of 40 patients (22.5%) in the Pre-CS group vs. 28 of 105 patients (26.7%) in the Post-CS group achieved a complete remission (CR) at 1 year, 29...
2017: European Neurology
https://www.readbyqxmd.com/read/28738380/scoring-neuropsychological-tests-what-corrections-need-to-be-considered
#9
Yassar Alamri
No abstract text is available yet for this article.
2017: European Neurology
https://www.readbyqxmd.com/read/28738376/evaluation-of-the-impact-of-cognitive-training-on-quality-of-life-in-patients-with-multiple-sclerosis
#10
Maria Grazia Grasso, Marco Broccoli, Paolo Casillo, Sheila Catani, Luca Pace, Alessandra Pompa, Francesco Rizzi, Elio Troisi
OBJECTIVE: The aim of this study was to evaluate the effectiveness of cognitive rehabilitation in a group of multiple sclerosis (MS) patients. METHODS: Thirty-four patients were included in this study and randomly allocated either to treatment with multidisciplinary rehabilitation plus cognitive training or to treatment with multidisciplinary rehabilitation alone. RESULTS: After 3 months of cognitive treatment, the patients assigned to the rehabilitation plus cognitive training group displayed an improvement in the cognitive test of executive function and a marked improvement in quality of life (QoL)...
2017: European Neurology
https://www.readbyqxmd.com/read/28738370/drug-level-monitoring-on-admission-for-presurgical-epilepsy-evaluation
#11
Irina Constantinescu, Christian M Korff, Serge Vulliemoz, Fabienne Picard, Margitta Seeck
OBJECTIVE: Evaluation for surgical treatment is offered to patients who do not respond to antiepileptic drugs. Pseudo-pharmacoresistance (PPR) has been described in the context of impaired compliance, incorrect diagnosis of epilepsy or pharmacological interference resulting in too low blood levels. We were interested to determine the frequency and causes of PPR in patients admitted for presurgical evaluation. METHODS: We reviewed 553 drug levels in 199 patients and analyzed the relative frequency of drugs below reference range (10 and 20% below the range)...
2017: European Neurology
https://www.readbyqxmd.com/read/28738366/neuroanatomical-correlates-of-hypophonia-in-subcortical-vascular-cognitive-impairment
#12
Ji Hye Yoon, Yisuh Ahn, Sook Hui Kim, Juhee Chin, Seongbeom Park, Duk L Na
BACKGROUND/AIMS: Early detection and intervention may alter the disease course of subcortical vascular cognitive impairment (SVCI). Patients with SVCI have white matter ischemia that disrupts connections between the cortex and subcortical gray matter and therefore manifest various symptoms such as motor disturbances and behavioral/cognitive dysfunction. Reduced vocal loudness, or hypophonia, is one of the common motor symptoms of SVCI, but few studies have systematically investigated it in this patient population...
2017: European Neurology
https://www.readbyqxmd.com/read/28738334/time-course-of-radiological-imaging-and-variable-interindividual-symptoms-in-amyotrophic-lateral-sclerosis-and-frontotemporal-dementia-associated-with-p-arg487his-mutation-in-the-vcp%C3%A2-gene
#13
Makito Hirano, Yuko Yamagishi, Satoshi Yanagimoto, Kazumasa Saigoh, Yusaku Nakamura, Susumu Kusunoki
To our knowledge, this is the first study to report the time course of radiological imaging of 3 patients from 2 families with VCP-related amyotrophic lateral sclerosis (ALS) and dementia. Both families shared the same p.Arg487His mutation in the VCP gene encoding valosin-containing protein. The first patient started to have a typical form of ALS, followed by dementia 7 years later. The second patient, a brother of the first one, had frontotemporal dementia and parkinsonism. The third patient had simultaneous ALS and dementia...
2017: European Neurology
https://www.readbyqxmd.com/read/28697504/effects-of-a-training-program-involving-body-cooling-on-physical-and-cognitive-capacities-and-quality-of-life-in-multiple-sclerosis-patients-a-pilot-study
#14
Benoit Gonzales, Gilles Chopard, Benjamin Charry, Eric Berger, Julien Tripard, Eloi Magnin, Alain Groslambert
OBJECTIVE: Two methods using exercise and body cooling could influence the well-being of patients with multiple sclerosis (PwMS). The aim of this study was to determine whether wearing a cooling vest during a physical training program could increase the cognitive and physical capacities and quality of life in PwMS. METHODS: Eighteen PwMS (49.6 ± 8 years; Expanded Disability Status Score 5.0 ± 1.0) were randomly assigned to a cooling or control group. PwMS underwent a 7-week physical training program...
2017: European Neurology
https://www.readbyqxmd.com/read/28647732/perioperative-strokes-following-surgical-correction-of-mitral-valves-a-systematic-review-and-meta-analysis
#15
Reshmi Udesh, Piruthiviraj Natarajan, Vinodh Jeevanantham, Thomas G Gleason, Vinay Badhwar, Parthasarathy D Thirumala
OBJECTIVE: The primary aim of this meta-analysis was to quantify the impact of perioperative strokes on stroke-related mortality after open mitral valve (MV) procedures were performed. METHODS: An electronic search of the PubMed, Embase, and the Web of Science databases was performed to retrieve articles published up to December 2015, relevant to patients undergoing MV procedures. Data were extracted from the final list of 25 studies to calculate a summary OR for 30-day stroke-related mortality...
2017: European Neurology
https://www.readbyqxmd.com/read/28633136/malaria-fever-therapy-for-general-paralysis-of-the-insane-a-historical-cohort-study
#16
Ingrid M Daey Ouwens, C Elisabeth Lens, Aernoud T L Fiolet, Alewijn Ott, Peter J Koehler, Piet A Kager, Willem M A Verhoeven
BACKGROUND/AIMS: This year marks the 100th anniversary of the first malaria fever treatment (MFT) given to patients with general paralysis of the insane (GPI) by the Austrian psychiatrist and later Nobel laureate, Julius Wagner-Jauregg. In 1921 Wagner-Jauregg reported an impressive therapeutic success of MFT and it became the standard treatment for GPI worldwide. In this study, MFT practice in the Dutch Vincent van Gogh psychiatric hospital in GPI patients who had been admitted in the period 1924-1954 is explored...
2017: European Neurology
https://www.readbyqxmd.com/read/28624820/an-elevated-high-sensitivity-c-reactive-protein-level-is-associated-with-unfavorable-functional-outcomes-of-small-artery-occlusion-in-patients-without-diabetes
#17
Yuan Gao, Ji Liu, Wanjun Wang, Chunlin Gao, Changshen Yu, Shoufeng Liu, Jialing Wu
BACKGROUND: High-sensitivity C-reactive protein (hs-CRP) is associated with a risk of causing diabetes mellitus and ischemic stroke. However, the association between hs-CRP levels and functional outcome after small-artery occlusion (SAO) is unknown. METHODS: Data for 836 patients diagnosed with SAO were collected from the Department of Neurorehabilitation of Huanhu Hospital. Hs-CRP values were classified according to quartiles (<0.67, 0.67 to <1.46, 1.46 to <3...
2017: European Neurology
https://www.readbyqxmd.com/read/28618415/disconnections-of-cortico-subcortical-pathways-related-to-cognitive-impairment-in-patients-with-leukoaraiosis-a-preliminary-diffusion-tensor-imaging-study
#18
Jun-Liang Yuan, Shuang-Kun Wang, Xiao-Juan Guo, Lei-Lei Teng, Hua Jiang, Hua Gu, Wen-Li Hu
BACKGROUND: We aimed to explore the relation between the microstructural integrity of white matter using the technique of diffusion tensor imaging (DTI) and changes of cognition in leukoaraiosis (LA). METHODS: Fifty patients with LA and 50 age- and gender-matched controls were recruited consecutively. The average values of mean diffusivity (MD) and fractional anisotropy (FA) were quantified both within white matter lesions (WMLs) and normal-appearing white matter (NAWM) from the regions of interest (ROIs)...
2017: European Neurology
https://www.readbyqxmd.com/read/28586773/comparison-of-the-clinical-effectiveness-of-ultrasound-guided-corticosteroid-injection-with-and-without-needle-release-of-the-transverse-carpal-ligament-in-carpal-tunnel-syndrome
#19
Xuan-Yan Guo, Mao-Xiang Xiong, Yu Zhao, Fan-Ding He, Xue-Qing Cheng, Yan-Yan Wu, Kai Chen, Man Lu
BACKGROUND: To compare the clinical effectiveness of ultrasound-guided corticosteroid injection with and without needle release of the transverse carpal ligament (TCL) in carpal tunnel syndrome (CTS). METHODS: Between May 2014 and June 2016, 52 patients (56 wrists) with CTS were included in this study. Among these patients, 28 wrists were treated with ultrasound-guided corticosteroid injection plus needle release of the TCL (group A) and 28 wrists were treated with a single ultrasound-guided corticosteroids injection (group B)...
2017: European Neurology
https://www.readbyqxmd.com/read/28578330/the-efficacy-of-high-frequency-repetitive-transcranial-magnetic-stimulation-for-improving-apathy-in-chronic-stroke-patients
#20
Nobuyuki Sasaki, Takatoshi Hara, Naoki Yamada, Masachika Niimi, Wataru Kakuda, Masahiro Abo
Although repetitive transcranial magnetic stimulation (rTMS) for hemiparesis is beneficial, so far no study has examined the usefulness of rTMS for apathy. Thirteen patients with chronic stroke were assigned randomly to 2 groups: rTMS group (n = 7) and sham stimulation group (n = 6). The patients received 5 sessions of either high-frequency rTMS over the region spanning from the dorsal anterior cingulate cortex (dACC) to medial prefrontal cortex (mPFC) or sham stimulation for 5 days. The severity of apathy was evaluated using the Apathy Scale (AS) and the severity of depression was evaluated using the Quick Inventory of Depressive Symptomatology (QIDS) serially before and after the 5-day protocol...
2017: European Neurology
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