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European Neurology

Ewa Koziorowska-Gawron, Maciej Kaczorowski, Joanna Bladowska, Sławomir Budrewicz, Magdalena Koszewicz, Agnieszka Hałoń
We present a rare case of primary malignant melanoma of the central nervous system. We underline the difficulties we faced during diagnostic procedures. Finally, postmortem examination revealed the diagnosis of primary pauci--melanotic leptomeningeal melanomatosis.
September 19, 2018: European Neurology
Ana Inês Martins, João Sargento-Freitas, Joana Jesus-Ribeiro, Inês Correia, Leila Cardoso, João Pedro Gomes, Mariana Gonçalves, Rui Costa, Fernando Silva, Orlando Galego, César Nunes, José Beato-Coelho, Ricardo Varela, Cristina Machado, Bruno Rodrigues, Gustavo C Santo, Luís Cunha
We performed a retrospective study with the aim of investigating the association between blood pressure (BP) variability in the first 24 h after ischemic stroke and functional outcome, regarding arterial recanalization status. A total of 674 patients diagnosed with acute stroke and treated with revascularization therapies were enrolled. Systolic and diastolic BP values of the first 24 h after stroke were collected and their variation quantified through standard deviation. Recanalization state was evaluated at 6 h and clinical outcome at 3 months was assessed by modified Rankin Scale...
September 18, 2018: European Neurology
Masafumi Nozoe, Miho Yamamoto, Miki Kobayashi, Masashi Kanai, Hiroki Kubo, Shinichi Shimada, Kyoshi Mase
Autonomic dysfunction is one of the predictors of poor outcome in patients with acute ischemic stroke. We compared the heart rate variability (HRV) during early mobilization in patients with or without neurological deterioration (ND). We enrolled 7 acute ischemic patients with ND and 14 without ND and measured their HRV in the rest and mobilization by electrocardiography. There was a significant difference in sympathetic nervous activity during mobilization between the 2 groups. However, no significant differences in blood pressure, heart rate, and parasympathetic nerve activity were observed...
September 11, 2018: European Neurology
Alexandre Morin, Marc Teichmann
This study provides a literature-based overview of jargonaphasia in primary progressive aphasias (PPA) exploring its occurrence, phenotypes, and anatomical underpinnings, while adding 2 novel cases with prototypical jargon. We report 26 jargonaphasia cases, initially diagnosed with semantic or logopenic PPA, resulting in semantic or phonological jargon, respectively. Brain damage in literature and our cases encompassed superior temporal cortices involved in language monitoring, the temporal-parietal junction for phonological jargon and temporal poles for semantic jargon...
September 11, 2018: European Neurology
Moonyoung Jeong, Won Sik Kim, Ah-Ran Kim, Jeong Jin Park, Dong-Hee Choi, Hahn Young Kim
BACKGROUND: Transient global amnesia (TGA) is an interesting clinical syndrome characterized by sudden memory loss for recent events and an inability to retain new memories usually lasting several hours and recovering spontaneously. We conducted a literature search of medical procedure-related TGA and its predisposing conditions. METHODS: We performed PubMed searches using the keyword "transient global amnesia" combined with "procedure," "test," "therapy," or various other individual medical procedures...
September 11, 2018: European Neurology
Katharina M Hösl, Martina Deutsch, Ruihao Wang, Sankanika Roy, Klemens Winder, Günter Niklewski, De-Hyung Lee, Ralf A Linker, Max J Hilz
BACKGROUND: In women with multiple sclerosis (MS), depression and sexual dysfunction (SD) are common. Whether SD promotes depression or vice versa remains unclear despite therapeutic relevance. Therefore, we aimed to assess whether SD more likely triggers depression or vice versa. METHODS: In 83 female MS patients and 21 age-matched healthy women, we assessed depression, using the Beck Depression Inventory-V (BDI-V), and SD using the Female Sexual Function Index (FSFI)...
August 31, 2018: European Neurology
Jiayue Ding, Da Zhou, Tingting Geng, Liqun Pan, Jingyuan Ya, Zhongao Wang, Yanyu Hu, Yuchuan Ding, Xuxiang Zhang, Ran Meng
BACKGROUND: Visual damage is one of the most common complications of cerebral venous sinus thrombosis (CVST)-associated intracranial hypertension (IH). This study is aimed at stratifying the risk of IH-induced visual damage in an attempt to predict its deterioration and prevent high-risk patients from irreversible eyesight impairment promptly. METHODS: A total of 94 patients with confirmed diagnosis of CVST were eligible for enrollment in this study. According to cerebrospinal fluid pressure at admission, the involved patients were classified into mild IH (< 250 mmH2O), moderate IH (250-330 mmH2O), and severe IH (≥330 mmH2O) groups...
August 22, 2018: European Neurology
Taim A Muayqil, Mohammed H Alanazy, Maan J Al-Herbish, Mohammed Al-Nafisah, Lubna M Halawani, Sakhar S Al-Bader, Lujain M Al-Yousef, Bandar N Aljafen
OBJECTIVE: Graphesthesia is the ability to identify a symbol traced on the skin. Agraphesthesia is the impairment in this ability and is encountered in various disorders of the somatosensory pathways. We aimed to describe the demographic and symbolic features that influence correct recognition of Arabic graphesthesia stimuli in healthy Arabic individuals. METHODS: Participants were community dwelling healthy Arabian individuals of 18 years of age or older. Demographic information collected included age, gender, years of education, and hand dominance...
August 21, 2018: European Neurology
Bo-Yu Chen, Pao-Sheng Yen, Chun-Chi Chiang, Pei-Hsuan Lin, Hui-Chun Huang
No abstract text is available yet for this article.
August 8, 2018: European Neurology
Krzysztof Pietrzak
Józef Brudziński's (1874-1917) contribution to the field of neurology is noteworthy and undeniable. His organizational efforts and research activity have earned him the name of the "father of the Polish paediatrics". He described the Brudzinski reflex and Brudzinski neck sign. He proved that the symptoms of these conditions were caused by nerve root irritation and elevated CSF pressure. He also described cheek phenomenon and symphyseal sign.
August 8, 2018: European Neurology
Wanying Shan, Dong Yang, Huaiming Wang, Liang Xu, Meng Zhang, Wenhua Liu, Wenjie Zi, Yonggang Hao, Yunyun Xiong, Gelin Xu, Xinfeng Liu
BACKGROUND AND PURPOSE: Clinical trials showed that anesthesia may not influence the functional outcome in stroke patients with endovascular therapy; however, data are lacking in China. Using real-world registry data, our study aims to compare the effects of general anesthesia or conscious sedation on functional outcomes in stroke patients treated with thrombectomy in China. METHODS: Consecutive patients with acute anterior circulation stroke receiving thrombectomy in 21 stroke centers between January 2014 and June 2016 were included in this study...
July 26, 2018: European Neurology
Min Qian, Haitao Ren, Tao Qu, Zhaohui Lu, Yueli Zou, Junying He, Yanhuan Zhao, Lin Chen, Hongzhi Guan
BACKGROUND: Neurocutaneous melanocytosis (NCM) is a poorly understood disease due to its rarity. This study aimed to summarize the characteristics of adult NCM and improve the awareness of this disease. METHODS: The clinical data of 13 adult patients with NCM were retrospectively reviewed, including neuroimages, cerebrospinal fluid (CSF), and histological features. RESULTS: There were 9 males and 4 females. The mean age at symptom onset was 36...
July 13, 2018: European Neurology
Fang Yuan, Ruihua Jia, Qiong Gao, Fang Yang, Xiai Yang, Yongli Jiang, Wen Li, Lara V Marcuse, Wen Jiang
BACKGROUND: Drug-resistant epilepsy (DRE) is a common and serious consequence of convulsive status epilepticus (CSE). Little is known on the early prediction of DRE development after CSE. Our aim was to identify independent DRE predictors in patients with CSE. METHODS: One hundred and forty consecutive patients identified with CSE in a tertiary academic hospital between March 2008 and January 2015 were reviewed. Demographics, clinical features, serum albumin neuroimaging, and electroencephalogram characteristics were collected and analyzed...
2018: European Neurology
Junya Aoki, Kentaro Suzuki, Satoshi Suda, Seiji Okubo, Masahiro Mishina, Yasuhiro Nishiyama, Yuki Sakamoto, Kazumi Kimura
BACKGROUND: It is unknown whether the effect of onset---to-door (OTD) time on clinical outcomes differs between -patients with and without large artery occlusion (LAO) who undergo hyperacute recanalization therapy. METHODS: Hyperacute recanalization therapy includes intravenous thrombolysis tissue-plasminogen activator (tPA), and endovascular therapy (EVT). Favorable clinical outcome was defined as modified Rankin Scale of ≤2 at discharge. RESULTS: Among 164 patients, 117 (71%) patients received tPA, 86 (52%) received EVT, and 39 (24%) received tPA and EVT...
2018: European Neurology
Ivan Adamec, Anamari Junakovic, Magdalena Krbot Skorić, Mario Habek
AIM: The aim of this study was to investigate the association of autonomic nervous system abnormalities on head-up tilt table test (HUTT) with generalized joint hypermobility, expressed by Beighton score (BS). METHODS: This was a prospective study that included 115 consecutive patients (91 females; mean age 34.35 ± 14.11) referred either for the HUTT or testing of the cardiovascular autonomic reflexes together with HUTT. Generalized joint hypermobility was evaluated according to the BS system after which HUTT was performed...
2018: European Neurology
Bruno Niemeyer, Bernardo Muniz, Edson Marchiori
No abstract text is available yet for this article.
2018: European Neurology
Valentina Mancini, Giulio Mastria, Viviana Frantellizzi, Alessandro Viganò, Nikolaos Petsas, Saadi Sollaku, Martina Fanella, Carlo Di Bonaventura, Mauro Liberatore, Vittorio Di Piero
No abstract text is available yet for this article.
2018: European Neurology
Marco Luigetti, Tommaso Nicoletti, Raffaele Iorio, Claudia Papi, Vittorio Riso, Emilio Lozupone, Gabriella Silvestri
No abstract text is available yet for this article.
2018: European Neurology
Navnika Gupta, Sanjay Pandey
BACKGROUND: After a stroke, movement disorders are rare manifestations mainly affecting the deep structures of the brain like the basal ganglia (44%) and thalamus (37%), although there have been case studies of movement disorders in strokes affecting the cerebral cortex also. SUMMARY: This review aims to delineate the various movement disorders seen in association with thalamic strokes and tries to identify the location of the nuclei affected in each of the described movement disorders...
2018: European Neurology
Xinmiao Zhang, Jing Jing, Xingquan Zhao, Liping Liu, Chunxue Wang, Yuesong Pan, Xia Meng, Yilong Wang, Yongjun Wang
OBJECTIVES: Statin use during hospitalization improves prognosis in patients with ischaemic stroke. However, it remains uncertain whether acute ischaemic stroke patients with chronic kidney disease (CKD) benefit from statin therapy. We investigated the effect of statin use during hospitalization in reducing short-term mortality of patients with ischaemic stroke and CKD. METHODS: Data of first-ever ischaemic stroke patients without a history of pre-stroke statin treatment was derived from the China National Stroke Registry...
2018: European Neurology
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