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European Neurology

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https://www.readbyqxmd.com/read/29131095/intracranial-internal-carotid-artery-wall-calcification-in-ischemic-strokes-treated-with-thrombolysis
#1
Miguel Tábuas-Pereira, João Sargento-Freitas, Fernando Silva, Joana Parra, Patrícia Mendes, Vera Seara, Miguel Mesquita, Mariana Baptista, Gustavo Cordeiro, Luis Cunha
BACKGROUND: Calcifications are an important element of atherosclerotic plaques and have been used as a marker of atherosclerosis and clinical outcome predictor in different vascular territories. CT-scan, performed in the acute ischemic stroke setting, can reliably detect intracranial arterial calcifications. OBJECTIVES: To investigate the association between intracranial internal carotid artery calcification and functional outcome, symptomatic intracerebral hemorrhage (sICH), recanalization, and death...
November 13, 2017: European Neurology
https://www.readbyqxmd.com/read/29131091/apathy-profile-in-parkinson-s-and-huntington-s-disease-a-comparative-cross-sectional-study
#2
Mário Sousa, Fradique Moreira, Joana Jesus-Ribeiro, Inês Marques, Flávia Cunha, Nádia Canário, António Freire, Cristina Januário
BACKGROUND/AIMS: Apathy is one of the most frequent, disabling and difficult-to-treat symptoms that show up in many neurodegenerative disorders. The aim of this study was to assess and compare apathy profile in Parkinson's and Huntington's patients using the same comprehensive instruments to measure apathy, cognition and depressive symptoms. MATERIALS AND METHODS: We consecutively assessed Parkinson's disease (PD) and Huntington's disease (HD) patients recruited from a Movement Disorders Unit...
November 13, 2017: European Neurology
https://www.readbyqxmd.com/read/29131019/utility-of-autonomic-function-tests-to-differentiate-dementia-with-lewy-bodies-and-parkinson-disease-with-dementia-from-alzheimer-disease
#3
Shuta Toru, Tadashi Kanouchi, Takanori Yokota, Yosuke Yagi, Akira Machida, Takayoshi Kobayashi
OBJECTIVE: We studied autonomic disturbance in patients with dementia with Lewy bodies (DLB), Parkinson disease with dementia (PDD), Alzheimer disease (AD), to determine whether autonomic function tests can be used to distinguish these disorders. METHODS: Autonomic function was tested in 56 patients with DLB, 37 patients with PDD, and 59 patients with AD by using the sympathetic skin response, coefficient of variation in R-R interval, the head-up tilt test, serum norepinephrine concentration, and 123I-meta-iodobenzylguanidine cardiac scintigraphy...
November 13, 2017: European Neurology
https://www.readbyqxmd.com/read/29131011/dizziness-and-the-acute-vestibular-syndrome-at-the-emergency-department-a-population-based-descriptive-study
#4
Micaela Ljunggren, Julia Persson, Jonatan Salzer
BACKGROUND: Dizziness is a common occurrence witnessed at emergency departments (EDs). This study aims to describe the epidemiology and management of dizzy patients with and without an acute vestibular syndrome (AVS) in the ED at Umeå University Hospital. METHODS: A total of n = 2,126 ED dizziness visits during 3 years were identified. Data were obtained through retrospective review of medical records. Cases were stratified based on presentation, including AVS and neurological deficits...
November 13, 2017: European Neurology
https://www.readbyqxmd.com/read/29130982/aphasia-following-left-putaminal-hemorrhage-at-a-rehabilitation-hospital
#5
Shinichiro Maeshima, Sayaka Okamoto, Hideto Okazaki, Reisuke Funahashi, Shigenori Hiraoka, Hirokazu Hori, Kei Yagihashi, Ikuko Fuse, Shinichiro Tanaka, Naoki Asano, Shigeru Sonoda
OBJECTIVE: We aimed to clarify the relationship between aphasia and hematoma type/volume in patients with left putaminal hemorrhage admitted to a rehabilitation facility. METHODS: We evaluated the relationship between the presence, type, and severity of aphasia and hematoma type/volume in 92 patients with putaminal hemorrhage aged 29-83 years. Hematoma type and volume were evaluated on the basis of CT images obtained at stroke onset. The Standard Language Test for Aphasia was conducted as part of the initial assessment...
November 9, 2017: European Neurology
https://www.readbyqxmd.com/read/29084403/high-frequency-of-sleep-disorders-in-parkinson-s-disease-and-its-relationship-with-quality-of-life
#6
Manoel Alves Sobreira-Neto, Márcio Alexandre Pena-Pereira, Emmanuelle Silva Tavares Sobreira, Marcos Hortes Nisihara Chagas, Regina Maria França Fernandes, Vitor Tumas, Alan Luiz Eckeli
OBJECTIVES: To determine the frequency of major sleep disorders in patients with Parkinson's disease (PD), diagnosed according to the third international classification of sleep disorders, and assess the relationship of those disorders with the quality of life. METHODS: A cross-sectional study was performed involving 88 consecutive patients with PD from outpatient clinic. Participants were subjected to clinical interviews, assessment using standardized scales (Epworth Sleepiness Scale, PD Questionnaire, Pittsburgh sleep quality index (PSQI) and, for individuals with a diagnosis of RLS/WED, International RLS/WED grading scale), and video-polysomnography...
October 30, 2017: European Neurology
https://www.readbyqxmd.com/read/29073634/demographic-clinical-and-polysomnographic-characteristics-of-childhood-and-adult-onset-sleepwalking-in-adults
#7
Panagiotis Bargiotas, Iris Arnet, Michael Frei, Christian R Baumann, Kaspar Schindler, Claudio L Bassetti
BACKGROUND: Sleepwalking (SW) is found to affect children predominantly, but it can persist or appear de novo even among adults. In this study, we assessed the demographic, clinical and polysomnographic profile, trigger factors and associated comorbidities of adult-onset (AO-SW) and childhood-onset (CO-SW) adult sleepwalkers. METHODS: In adult sleepwalkers, a structured clinical interview, a battery of questionnaires, video-polysomnography (v-PSG) and standard electroencephalography (EEG) were performed...
October 26, 2017: European Neurology
https://www.readbyqxmd.com/read/29073632/jean-martin-charcot-1825-1893-a-treatment-approach-gone-astray
#8
Olivier Walusinski
Jean-Martin Charcot's reputation remains that of a physician who took little interest in treatments for the neurological diseases he did much to identify. After reviewing the limited number of medicinal remedies of slight effectiveness at Charcot's disposal, we analyze in this review the numerous therapeutic tests that he conducted: vibratory medicine for Parkinson's disease, treatment of tabes by suspension technique, metallotherapy and moral -treatment for hysteria. Understanding that he fully and completely adhered to the far-reaching heredity-based theories of his day makes it possible to perceive his natural and fundamental pessimism...
October 26, 2017: European Neurology
https://www.readbyqxmd.com/read/29073622/a-callosal-lesion
#9
Christian Schmidt, Mark Obermann
No abstract text is available yet for this article.
October 26, 2017: European Neurology
https://www.readbyqxmd.com/read/29073608/neuropsychological-training-of-attention-improves-ms-related-fatigue-results-of-a-randomized-placebo-controlled-double-blind-pilot-study
#10
Peter Flachenecker, Heike Meissner, Rebecca Frey, Wolfgang Guldin
BACKGROUND: Attentional deficits may be pathophysiologically relevant in MS-associated fatigue. PATIENTS AND METHODS: Thirty MS patients with fatigue and attentional deficits in neuropsychological testing participated in this randomized, placebo-controlled, double-blind trial. The intervention group (IG; n = 14) was treated with 10 h of computerized, specific neuropsychological training performing simple reaction time tasks, whereas the control group (CG; n = 16) also runs through computerized, but unspecific neuropsychological training using tasks without time components...
October 26, 2017: European Neurology
https://www.readbyqxmd.com/read/29073592/dronabinol-is-a-safe-long-term-treatment-option-for-neuropathic-pain-patients
#11
Sebastian Schimrigk, Martin Marziniak, Christine Neubauer, Eva Maria Kugler, Gudrun Werner, Dimitri Abramov-Sommariva
Treatment of neuropathic pain (NP) symptoms associated with multiple sclerosis (MS) is frequently insufficient. Yet, cannabis is still rarely offered for treatment of pain. This clinical trial aimed at showing the positive benefit-risk ratio of dronabinol. Two hundred forty MS patients with central NP entered a 16-weeks placebo-controlled phase-III study followed by a 32-weeks open-label period. One hundred patients continued therapy for overall up to 119 weeks. Primary endpoint was change of pain intensity on the 11-point Numerical Rating Scale over a 16-weeks treatment period...
October 26, 2017: European Neurology
https://www.readbyqxmd.com/read/29049993/less-limb-muscle-involvement-in-myositis-patients-with-anti-mitochondrial-antibodies
#12
Takeshi Uenaka, Hisatomo Kowa, Yoshihisa Ohtsuka, Tsuneyoshi Seki, Kenji Sekiguchi, Fumio Kanda, Tatsushi Toda
Recent studies have revealed the clinical, histological, and pathophysiological characteristics in a group of inflammatory myopathies with selected autoantibodies. We retrospectively compared the clinical manifestations and histological features between 8 anti-mitochondrial (anti-M2) antibody-positive and 33 antibody-negative patients. Patients with anti-M2 antibodies have been previously reported to have delayed diagnostic confirmation and frequent cardiopulmonary complications in comparison to those without the antibodies...
October 19, 2017: European Neurology
https://www.readbyqxmd.com/read/29017164/aspirin-prophylaxis-for-migraine-with-aura-an-observational-case-series
#13
Wendy E Turk, Anouk Uiterwijk, Raphaël Pasmans, Vera Meys, Cenk Ayata, Peter J Koehler
No abstract text is available yet for this article.
October 10, 2017: European Neurology
https://www.readbyqxmd.com/read/28992626/multiple-sclerosis-and-clinical-gait-analysis-before-and-after-fampridine-a-systematic-review
#14
Magaly Lecat, Pierre Decavel, Eloi Magnin, Brigitte Lucas, Vincent Gremeaux, Yoshimasa Sagawa
BACKGROUND: Gait impairment is one of the most disabling symptoms in people with multiple sclerosis (PwMS). Fampridine, has demonstrated a positive effect on gait speed in PwMS after 14 days of treatment but the long-term effects have not yet been demonstrated. This study reviews the long-term effects of fampridine on gait in PwMS. SUMMARY: This systematic review was conducted according to the PRISMA statement. Studies were considered long term if treatment exceeded 28 days...
October 9, 2017: European Neurology
https://www.readbyqxmd.com/read/28972953/sudden-fixed-posturing-beyond-functional-psychogenic-dystonia
#15
Vanessa Carvalho, João Massano, Sara França, Catarina Cruto
No abstract text is available yet for this article.
October 3, 2017: European Neurology
https://www.readbyqxmd.com/read/28957815/clinical-relevance-of-patent-foramen-ovale-and-atrial-septum-aneurysm-in-stroke-findings-of-a-single-center-cross-sectional-study
#16
Marlena Schnieder, Tariq Siddiqui, André Karch, Mathias Bähr, Gerd Hasenfuss, Jan Liman, Marco R Schroeter
BACKGROUND: A significant proportion of ischemic strokes are cryptogenic. In this context, the clinical pertinence of patent foramen ovale (PFO) with and without atrial septum aneurysm (ASA) remains controversial. The aim of this study was to identify how PFO +/-ASA and cryptogenic stroke are associated in a representative sample of stroke patients. METHODS: We enrolled all patients (n = 909) with ischemic stroke or transient ischemic attack admitted to the certified stroke unit or neurological intensive care unit of our university medical center who underwent transesophageal echocardiography (TEE) between 2012 and 2014...
September 28, 2017: European Neurology
https://www.readbyqxmd.com/read/28942453/the-rapid-neuropsychological-test-battery-for-subjects-aged-50-89-from-norms-to-cognitive-profile
#17
Géraldine Sylvestre, Frédéric Mauny, Marie Lavaux, Marc Puyraveau, Mickael Binetruy, Agatha Meyer, Pierre Vandel, Jean Galmiche, Gilles Chopard
BACKGROUND/AIMS: It is well established that healthy adults obtain low performances when simultaneously interpreting the results of multiple tests. The aim of this study was to estimate the proportion of French-speaking healthy older adults with low scores for the RAPID (Réseau d'Aide au diagnostic et à la PrIse en charge des Détériorations cognitives et de maladies neurologiques chroniques en Franche-Comté et au niveau national) battery test and consider different combinations of test scores within a specific domain and across different domains...
September 22, 2017: European Neurology
https://www.readbyqxmd.com/read/28942452/automated-mechanical-repositioning-treatment-for-posterior-canal-benign-paroxysmal-positional-vertigo-a-single-center-experience-and-literature-review
#18
Xiaolei Liu, Roi Treister, Yinan Yan, Hailong Wang, Xinyi Li
OBJECTIVE: To evaluate the feasibility and effectiveness of automated mechanical repositioning treatment (AMRT) for posterior canal benign paroxysmal positional vertigo -(PC-BPPV). PATIENTS AND METHODS: We reviewed all PC-BPPV patients admitted to our department between January and -December 2016. The inclusion criteria mainly required conducting a diagnosis for PC-BPPV by using the Dix-Hallpike test, a PC-BPPV history within 1 month, no intake of medications for the last 48 h...
September 22, 2017: European Neurology
https://www.readbyqxmd.com/read/28942450/cognitive-function-and-prognosis-of-multimodal-neuroimage-guided-thrombectomy-on-mild-to-moderate-anterior-circulation-infarction-patients-with-broadened-therapeutic-window-a-prospective-study
#19
Guodong Xu, Xiaoli Dong, Xiaoli Niu, Guimin Zheng, Hebo Wang, Fan Zhang, Litao Li, Peiyuan Lv
BACKGROUND AND OBJECTIVES: Endovascular mechanical thrombectomy is an important approach for acute ischemic stroke (AIS) treatment. Multimodal neuroimaging methods ideally provide the exact localization, extent, and metabolic activity of target tissues. Post-stroke cognitive impairment has recently been realized to be another major concern except for neurological function impairment. The aim of our study was to carry out a prospective study to compare neurological and cognitive functions after thrombectomy in mild to moderate anterior circulation infarction patients selected by multimodal neuroimaging...
September 22, 2017: European Neurology
https://www.readbyqxmd.com/read/28942441/the-clinical-characteristics-and-prognostic-analysis-of-status-epilepticus-in-northeast-china
#20
Lichao Sun, Chuntao Han, Weihong Lin
OBJECTIVE: Status epilepticus (SE) is a neurological emergency that may cause severe neurological deficiency and even death. The aim of this study was to analyze the clinical characteristics and prognosis of SE in northeast China. Additionally, the etiology and classification are discussed. MATERIALS AND METHODS: We retrospectively collected the clinical profiles of patients diagnosed with SE in the Epilepsy Center of Jilin University between January 2011 and May 2015...
September 22, 2017: European Neurology
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