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European Neurology

Ana Gonçalves, Catarina Brito, Rita Simões, José Vale
No abstract text is available yet for this article.
November 2, 2018: European Neurology
Tommaso Nicoletti, Anna Modoni, Simona Gaudino, Giovanni Frisullo
No abstract text is available yet for this article.
November 2, 2018: European Neurology
Ryuji Sakakibara, Ayami Shimizu, Osamu Takahashi, Fuyuki Tateno, Masahiko Kishi, Yosuke Aiba, Hiroyoshi Suzuki, Tatsuya Yamamoto, Chiharu Shibata, Tomonori Yamanishi
In order to investigate lower urinary tract function in hereditary spastic paraplegia (HSP), we recruited 12 HSP patients: 8 men, 4 women; mean age, 64.6 years; mean disease duration, 18.9 years; walk without cane, 2, walk with cane, 6, wheelchair bound, 3. We performed urinary symptom questionnaires and a urodynamic testing in all patients. As a result, urinary symptoms were observed in all but 3, including urinary urgency/frequency (also called overactive bladder) in 9 and hesitancy/poor stream in 6. Urodynamic abnormalities included detrusor overactivity during bladder filling in 10, underactive detrusor on voiding in 8 (detrusor hyperactivity with impaired contraction [DHIC] in 5), detrusor-sphincter dyssynergia (DSD) on voiding in 3, and post-void residual in 5...
November 2, 2018: European Neurology
Marcel Gebhardt, Peter Kropp, Frank Hoffmann, Uwe K Zettl
AIMS: Headaches have not been considered a typical symptom of multiple sclerosis (MS), although since 2000, almost every study showed high prevalence. We screened 50 MS patients at the time of first occurrence of neurological symptoms and found the highest prevalence of headache in MS that was ever recorded (78%). Postmortem histological analyses of MS patients' brains revealed lymphoid follicle-like structures in the cerebral meninges and a pathophysiological link between headache, and high inflammatory activity especially in the initial phase of MS could be suspected...
October 26, 2018: European Neurology
Pil-Wook Chung, Byung-Woo Yoon, Yeong-Bae Lee, Byoung-Soo Shin, Hahn Young Kim, Jae Hyeon Park, Byung-Kun Kim, Bong-Goo Yoo, Won-Chul Shin, Eung-Gyu Kim, Jin Kuk Do, Kyung-Pil Park, Yohan Jung, Woo-Keun Seo, Moon-Ku Han, Jei Kim, Yongduk Kim, Oh Young Bang, Yang-Ha Hwang, Jin-Hye Cha, Young-Joo Kim
Although statins are established therapy for the secondary prevention of ischemic stroke, factors associated with adherence to statin treatment following ischemic stroke are not well known. To address this, we assessed the 6-month statin adherence using 8-item Morisky Medication Adherence Scale-8 in patients with acute ischemic stroke. Of 991 patients, 65.6% were adherent to statin at 6-month after discharge. Multiple logistic regression analysis showed that patients' awareness of hyperlipidemia (OR 1.62; 95% CI 1...
2018: European Neurology
Jiaoting Jin, Fangfang Hu, Xing Qin, Xuan Liu, Min Li, Yonghui Dang, Jingxia Dang
PURPOSE: The diagnosis of Guillain-Barre syndrome (GBS) in the very early stage may be challenging. Our aim was to report the neurophysiological abnormalities in GBS within 4 days of clinical onset. We expected that GBS will be diagnosed by the assistance of neurophysiological study in the very early stage. METHODS: We prospectively recruited patients with a diagnosis of GBS discharged from First Affiliated Hospital of Xi'an Jiaotong University and Xi Jing Hospital...
2018: European Neurology
Mirla Avila, Arpana Bansal, John Culberson, Alan N Peiris
Multiple sclerosis (MS) is a chronic inflammatory demyelination disorder with an immune-mediated pathophysiology that affects the central nervous system (CNS). Like other autoimmune conditions, it has a predilection for female gender. This suggests a gender bias and a possible hormonal association. Inflammation and demyelination are hallmarks of MS. Oligodendrocytes are the myelinating cells of the CNS and these continue to be generated by oligodendrocyte precursor cells (OPCs). The process of remyelination represents a major form of plasticity in the developing adult CNS...
2018: European Neurology
Jingjing Li, Yi Li, Shihui Xing, Jian Zhang, Baoshan Qiu, Jinsheng Zeng, Yuhua Fan
BACKGROUND: Orthostatic hypotension (OH) is the key manifestation of autonomic dysfunction with many causes. Systemic neurological causes such as paraneoplastic syndrome are usually ignored. METHODS: We retrospectively analyzed clinical and examination data of 2 patients who were hospitalized, with onset symptom of OH and who were diagnosed as paraneoplastic syndrome. RESULTS: The patients were characteristic of an initial symptom of OH, positive anti-Hu antibody and albuminocytologic dissociation in the cerebrospinal fluid...
2018: European Neurology
Tyler M Saumur, Stephen D Perry
BACKGROUND: Motor imagery training implements neural adaptation theory to improve muscle strength without physically performing muscle contractions. To date, motor imagery training research regarding the efficacy of improving torque of the quadriceps over a brief training period is limited. OBJECTIVE: To determine the impact of a 3-week motor imagery training on peak torque during knee extension. METHOD: Ten young, healthy volunteers were randomly assigned to 1 of 3 groups over a 3-week period: strength training, motor imagery training and control...
2018: European Neurology
Man-Li Tong, Yu-Yan Chen, Xiao-Zhen Zhu, Kun Gao, Hui-Lin Zhang, Wei-Hong Zheng, Hui-Rong Wang, Li-Li Liu, Yong Lin, Li-Rong Lin, Tian-Ci Yang
BACKGROUND: The differential diagnosis of general paresis (GP) and non-neurosyphilis (NS) dementia is not clearly defined. The present study examined the differences in clinical and laboratory features of GP and non-NS dementia. MATERIALS AND METHODS: We retrospectively examined clinical and laboratory features of 85 GP patients and 196 non-NS dementia patients. Data were collected from Zhongshan Hospital between June 2005 and June 2014. RESULTS: The GP group had a higher percentage of males (83...
2018: European Neurology
(no author information available yet)
No abstract text is available yet for this article.
2018: European Neurology
Svetlana Blitshteyn, Pradeep Chopra
In the last decade, a group of chronic disorders associated with fatigue (CDAF) emerged as the leading cause of chronic fatigue, chronic pain, and functional impairment, all of which have been often labeled in clinical practice as chronic fatigue syndrome (CFS) or fibromyalgia. While these chronic disorders arise from various pathophysiologic mechanisms, a shared autoimmune or immune-mediated etiology could shift the focus from symptomatic treatment of fatigue and pain to targeted immunomodulatory and biological therapy...
2018: European Neurology
Ewa Koziorowska-Gawron, Maciej Kaczorowski, Joanna Bladowska, Sławomir Budrewicz, Magdalena Koszewicz, Agnieszka Hałoń
We present a rare case of primary malignant melanoma of the central nervous system. We underline the difficulties we faced during diagnostic procedures. Finally, postmortem examination revealed the diagnosis of primary pauci--melanotic leptomeningeal melanomatosis.
2018: European Neurology
Ana Inês Martins, João Sargento-Freitas, Joana Jesus-Ribeiro, Inês Correia, Leila Cardoso, João Pedro Gomes, Mariana Gonçalves, Rui Costa, Fernando Silva, Orlando Galego, César Nunes, José Beato-Coelho, Ricardo Varela, Cristina Machado, Bruno Rodrigues, Gustavo C Santo, Luís Cunha
We performed a retrospective study with the aim of investigating the association between blood pressure (BP) variability in the first 24 h after ischemic stroke and functional outcome, regarding arterial recanalization status. A total of 674 patients diagnosed with acute stroke and treated with revascularization therapies were enrolled. Systolic and diastolic BP values of the first 24 h after stroke were collected and their variation quantified through standard deviation. Recanalization state was evaluated at 6 h and clinical outcome at 3 months was assessed by modified Rankin Scale...
2018: European Neurology
Masafumi Nozoe, Miho Yamamoto, Miki Kobayashi, Masashi Kanai, Hiroki Kubo, Shinichi Shimada, Kyoshi Mase
Autonomic dysfunction is one of the predictors of poor outcome in patients with acute ischemic stroke. We compared the heart rate variability (HRV) during early mobilization in patients with or without neurological deterioration (ND). We enrolled 7 acute ischemic patients with ND and 14 without ND and measured their HRV in the rest and mobilization by electrocardiography. There was a significant difference in sympathetic nervous activity during mobilization between the 2 groups. However, no significant differences in blood pressure, heart rate, and parasympathetic nerve activity were observed...
2018: European Neurology
Alexandre Morin, Marc Teichmann
This study provides a literature-based overview of jargonaphasia in primary progressive aphasias (PPA) exploring its occurrence, phenotypes, and anatomical underpinnings, while adding 2 novel cases with prototypical jargon. We report 26 jargonaphasia cases, initially diagnosed with semantic or logopenic PPA, resulting in semantic or phonological jargon, respectively. Brain damage in literature and our cases encompassed superior temporal cortices involved in language monitoring, the temporal-parietal junction for phonological jargon and temporal poles for semantic jargon...
2018: European Neurology
Moonyoung Jeong, Won Sik Kim, Ah-Ran Kim, Jeong Jin Park, Dong-Hee Choi, Hahn Young Kim
BACKGROUND: Transient global amnesia (TGA) is an interesting clinical syndrome characterized by sudden memory loss for recent events and an inability to retain new memories usually lasting several hours and recovering spontaneously. We conducted a literature search of medical procedure-related TGA and its predisposing conditions. METHODS: We performed PubMed searches using the keyword "transient global amnesia" combined with "procedure," "test," "therapy," or various other individual medical procedures...
2018: European Neurology
Katharina M Hösl, Martina Deutsch, Ruihao Wang, Sankanika Roy, Klemens Winder, Günter Niklewski, De-Hyung Lee, Ralf A Linker, Max J Hilz
BACKGROUND: In women with multiple sclerosis (MS), depression and sexual dysfunction (SD) are common. Whether SD promotes depression or vice versa remains unclear despite therapeutic relevance. Therefore, we aimed to assess whether SD more likely triggers depression or vice versa. METHODS: In 83 female MS patients and 21 age-matched healthy women, we assessed depression, using the Beck Depression Inventory-V (BDI-V), and SD using the Female Sexual Function Index (FSFI)...
2018: European Neurology
Jiayue Ding, Da Zhou, Tingting Geng, Liqun Pan, Jingyuan Ya, Zhongao Wang, Yanyu Hu, Yuchuan Ding, Xuxiang Zhang, Ran Meng
BACKGROUND: Visual damage is one of the most common complications of cerebral venous sinus thrombosis (CVST)-associated intracranial hypertension (IH). This study is aimed at stratifying the risk of IH-induced visual damage in an attempt to predict its deterioration and prevent high-risk patients from irreversible eyesight impairment promptly. METHODS: A total of 94 patients with confirmed diagnosis of CVST were eligible for enrollment in this study. According to cerebrospinal fluid pressure at admission, the involved patients were classified into mild IH (< 250 mmH2O), moderate IH (250-330 mmH2O), and severe IH (≥330 mmH2O) groups...
2018: European Neurology
Taim A Muayqil, Mohammed H Alanazy, Maan J Al-Herbish, Mohammed Al-Nafisah, Lubna M Halawani, Sakhar S Al-Bader, Lujain M Al-Yousef, Bandar N Aljafen
OBJECTIVE: Graphesthesia is the ability to identify a symbol traced on the skin. Agraphesthesia is the impairment in this ability and is encountered in various disorders of the somatosensory pathways. We aimed to describe the demographic and symbolic features that influence correct recognition of Arabic graphesthesia stimuli in healthy Arabic individuals. METHODS: Participants were community dwelling healthy Arabian individuals of 18 years of age or older. Demographic information collected included age, gender, years of education, and hand dominance...
2018: European Neurology
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