journal
MENU ▼
Read by QxMD icon Read
search

Otolaryngologic Clinics of North America

journal
https://www.readbyqxmd.com/read/28318535/organism-and-microbiome-analysis-techniques-and-implications-for-chronic-rhinosinusitis
#1
REVIEW
Ashleigh A Halderman, Andrew P Lane
Modern advances in DNA sequencing have allowed for the development of culture-independent techniques with application to infectious and inflammatory conditions, such as rhinosinusitis. Although paradigm-changing discoveries have resulted from molecular microbiologic methods for a number of diseases, insights provided into the role of bacteria in chronic rhinosinusitis have yet to be fully understood to the point of impacting clinical diagnosis and management. As culture-independent techniques continue to evolve and become more refined, it is likely that a better understanding will emerge of how the microbiome influences chronic rhinosinusitis pathogenesis and response to therapy...
March 16, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28284452/advances-in-absorbable-biomaterials-and-nasal-packing
#2
REVIEW
Conner J Massey, Ameet Singh
Nasal biomaterials have been developed to improve postoperative outcomes after functional endoscopic sinus surgery (FESS). These products have been designed to overcome certain common complications in FESS, and to maximize patient comfort. This article evaluates the performance of nonabsorbable and absorbable packing with respect to these outcomes. The collected trials suggest superior performance of bioabsorbable packs compared with absorbable packs with respect to patient comfort. For hemostasis and wound healing, variation in performance metrics makes interstudy comparison difficult...
March 9, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28162242/endoscopic-resection-of-pterygopalatine-fossa-and-infratemporal-fossa-malignancies
#3
REVIEW
Gretchen M Oakley, Richard J Harvey
The endoscopic resection of pterygopalatine and infratemporal fossa malignancies allows excellent visualization and manipulation of tissues in an anatomically complex area compared with open approaches. With less approach morbidity, endoscopic endonasal surgery allows an easier recovery and earlier transition to adjuvant radiotherapy. The endoscopic approach is minimal access but rarely minimally invasive. Surgeons should not hesitate to gain wide surgical exposure of the pterygopalatine, infratemporal fossa, and petrocavernous carotid artery to ensure comfortable maneuverability and easy visualization of the tumor and its normal tissue margins...
February 2, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28162241/transfacial-and-craniofacial-approaches-for-resection-of-sinonasal-and-ventral-skull-base-malignancies
#4
REVIEW
Elizabeth L Perkins, Bryan M Brandon, Satyan B Sreenath, Dipan D Desai, Brian D Thorp, Charles S Ebert, Adam M Zanation
Malignancies of the paranasal sinuses and ventral skull base present unique challenges to physicians. A transfacial or craniofacial approach allows for wide, possibly en bloc resection and is ideal for tumors that involve surrounding soft tissue, the palate, the orbit, anterolateral frontal sinus, and lateral dura. Transfacial approaches include a lateral rhinotomy often combined with a medial, subtotal, or total maxillectomy. Reconstruction is most commonly performed with a pericranial flap to separate the intranasal and intracranial compartments...
February 2, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28162240/endoscopic-resection-of-sinonasal-and-ventral-skull-base-malignancies
#5
REVIEW
Ghassan Alokby, Roy R Casiano
The transnasal endoscopic resection of ventral skull base lesions represents a safe and effective method for the surgical management of sinonasal and ventral skull base malignancies in carefully selected cases. The goal of surgery is complete removal of all tumor with negative resection margins while maintaining the key oncological principles. Careful selection of cases along with the presence of an experienced surgeon and a fully involved multidisciplinary skull base team trained in the management of ventral skull base neoplasm are essential for excellent outcomes...
February 2, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28160998/overview-of-sinonasal-and-ventral-skull-base-malignancy-management
#6
REVIEW
Peter F Svider, Michael Setzen, Soly Baredes, James K Liu, Jean Anderson Eloy
Significant technological advances have fostered a movement toward minimally invasive surgical interventions for the management of ventral skull base malignancies. The care of patients with these lesions ideally involves an interdisciplinary skull base team that includes otolaryngologists, neurologic surgeons, radiation oncologists, and medical oncologists. This overview describes considerations essential for diagnosis, prognosis, and preoperative evaluation. Furthermore, surgical nuances, strategies for skull base reconstruction, and nonsurgical options are briefly discussed...
February 1, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28160997/the-role-of-chemotherapy-in-the-management-of-sinonasal-and-ventral-skull-base-malignancies
#7
REVIEW
George A Scangas, Jean Anderson Eloy, Derrick T Lin
In most cases of advanced sinonasal and ventral skull base cancer, a multimodal treatment approach provides the best chance for improved outcomes. Depending on the tumor type and extent of disease, systemic chemotherapy has been shown to play an important role in neoadjuvant, concomitant, and adjuvant settings. The lack of randomized trials continues to limit its indications. Further high-quality studies are needed to understand ideal chemotherapeutic regimens and their role and sequential timing in sinonasal and ventral skull base cancer...
February 1, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28160996/survival-morbidity-and-quality-of-life-outcomes-for-sinonasal-and-ventral-skull-base-malignancies
#8
REVIEW
Suat Kilic, Sarah S Kilic, Soly Baredes, James K Liu, Jean Anderson Eloy
Sinonasal and ventral skull base malignancies are a rare, heterogeneous group of cancers. Although prognosis usually depends on many factors, long-term survival rates remain low despite recent advances. Population-based databases are powerful resources for studying survival outcomes. However, institutional retrospective chart-review studies have been able to provide more insight on recurrence patterns, morbidity, and quality-of-life metrics, as well as more details of the treatment information that may affect outcomes...
February 1, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28160995/the-making-of-a-skull-base-team-and-the-value-of-multidisciplinary-approach-in-the-management-of-sinonasal-and-ventral-skull-base-malignancies
#9
REVIEW
Carl H Snyderman, Eric W Wang, Juan C Fernandez-Miranda, Paul A Gardner
The management of sinonasal and ventral skull base malignancies is best performed by a team. Although the composition of the team may vary, it is important to have multidisciplinary representation. There are multiple obstacles, both individual and institutional, that must be overcome to develop a highly functioning team. Adequate training is an important part of team-building and can be fostered with surgical telementoring. A quality improvement program should be incorporated into the activities of a skull base team...
February 1, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28104275/anatomic-considerations-for-sinonasal-and-ventral-skull-base-malignancy
#10
REVIEW
Thomas J Willson, Juan C Fernandez-Miranda, Cristian Ferrareze Nunes, Stefan Lieber, Eric W Wang
Malignancies of the sinonasal region and ventral skull base include a varied group of uncommon tumors that are a challenge to treat. These malignancies, with few exceptions, often present late because of their insidious growth and bland symptomatology. As with malignancies of other sites, the primary goal in surgical management is complete resection with negative margins. This presents a unique surgical challenge in that these lesions lie within a region of densely populated anatomic real estate. This fact reinforces the importance of complete preoperative work-up and a sound anatomic understanding...
January 16, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28104274/the-role-of-radiation-therapy-in-the-management-of-sinonasal-and-ventral-skull-base-malignancies
#11
REVIEW
Kyle Wang, Adam M Zanation, Bhishamjit S Chera
Sinonasal and ventral skull base malignancies are rare tumors that arise in a complex anatomic location juxtaposed with critically important normal tissues. The standard treatment paradigm for most histologies has been surgery followed by postoperative radiation therapy. Because of their propensity to present at an advanced stage and the presence of nearby critical structures, patients are at risk for severe radiation-induced long-term toxicity. Recent advances in radiotherapy technique have improved the therapeutic ratio between tumor control and normal tissue toxicity...
January 16, 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314409/sinonasal-and-ventral-skull-base-malignancies
#12
EDITORIAL
Jean Anderson Eloy, Michael Setzen, James K Liu
No abstract text is available yet for this article.
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314408/anterior-skull-base-malignancies-the-otolaryngologist-s-contribution
#13
EDITORIAL
Sujana S Chandrasekhar
No abstract text is available yet for this article.
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314407/population-based-results-in-the-management-of-sinonasal-and-ventral-skull-base-malignancies
#14
REVIEW
Rami Abdou, Soly Baredes
Population-based cancer registries allow for data collection on the scale of large populations, outside the limits of a single institution, and facilitate study of rare entities. The SEER database has been used to study more than 7000 cases encompassing a wide variety of relatively rare sinonasal malignant histologies. Clinically useful parameters have been gleaned from these analyses. Important limitations, such as omission of chemotherapy data, surgical approach used, type of radiation administered, and selection and confounding bias, should be considered...
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314406/the-role-of-targeted-therapy-in-the-management-of-sinonasal-malignancies
#15
REVIEW
Lawrence Kashat, Christopher H Le, Alexander G Chiu
Cancers develop secondary to genetic and epigenetic changes that provide the cell with a survival advantage that promotes cellular immortality. Malignancy arises when tumors use mechanisms to evade detection and destruction by the immune system. Many malignancies seem to elicit an immune response, yet somehow manage to avoid destruction by the cells of the immune system. Cancers may evade this immune response by numerous mechanisms. Several targeted immune therapies are available that block some of these inhibitory signals and enhance the cell-mediated immune response...
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314405/management-of-skull-base-defects-after-surgical-resection-of-sinonasal-and-ventral-skull-base-malignancies
#16
REVIEW
Jean Anderson Eloy, Emily Marchiano, Alejandro Vázquez, Michael J Pfisterer, Leila J Mady, Soly Baredes, James K Liu
Over the past 2 decades, there has been a significant increase in the resection of larger and more complex ventral skull base malignancies. The resection of these lesions has resulted in the creation of larger and more difficult to repair skull base defects. There are many available options for ventral skull base reconstruction. Despite the variety of reconstructive options, the key objective is to eliminate any communication between the intracranial space and the sinonasal cavity. This article discusses some of the more common techniques currently used for repair of these skull base defects...
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314404/the-role-of-robotic-surgery-in-sinonasal-and-ventral-skull-base-malignancy
#17
REVIEW
Ralph Abi Hachem, Sanjeet Rangarajan, Andre Beer-Furlan, Daniel Prevedello, Enver Ozer, Ricardo L Carrau
Over the past decade, robotic surgery has gained wide popularity, making a significant impact on multiple surgical specialties. In the head and neck arena, transoral robotic surgery has proven to be safe and associated with acceptable oncological and superior functional outcomes for surgery of the oropharynx, hypopharynx, supraglottis, and glottis; thus, changing the paradigm for the management of tumors in these anatomic locations. Robotic surgery of the ventral skull base is at an early stage of development...
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314403/management-of-cavernous-sinus-involvement-in-sinonasal-and-ventral-skull-base-malignancies
#18
REVIEW
Amol Raheja, William T Couldwell
Cavernous sinus (CS) involvement by sinonasal and ventral skull base malignancies is infrequently encountered in neurosurgical practice. Despite advancements in skull base microneurosurgery and endoscopic techniques, detailed knowledge and experience of the surgical management of these lesions are limited. This article elaborates on surgical strategies and approaches for CS involvement of malignant ventral skull base tumors. The article discusses the indications, techniques, nuances, advantages, limitations, and complications of minimally invasive CS biopsy, transcranial microscopic, and transfacial endoscopic approaches to the CS using illustrative diagrams and operative videos...
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314402/management-of-orbital-involvement-in-sinonasal-and-ventral-skull-base-malignancies
#19
REVIEW
Gregory S Neel, Thomas H Nagel, Joseph M Hoxworth, Devyani Lal
The orbit may be frequently involved by sinonasal or ventral skull base malignancy. This involvement bodes a poorer prognosis for survival. Multimodality therapy with surgery and radiation therapy is usually attempted to optimize local control and overall survival. Oncologic surgical resection with negative margins is critical to local control and survival. In the past, any involvement of the orbit was deemed to necessitate orbital sacrifice. However, contemporary studies show that in carefully selected cases, orbital preservation does not adversely impact survival...
April 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28314401/combined-endoscopic-and-open-approaches-in-the-management-of-sinonasal-and-ventral-skull-base-malignancies
#20
REVIEW
James K Liu, Anni Wong, Jean Anderson Eloy
Combined transcranial and endoscopic endonasal approaches remain useful in the treatment of ventral skull base malignancies. The extended bifrontal transbasal approach provides wide access to the anterior ventral skull base and paranasal sinuses without transfacial incisions. In more extensive lesions, the bifrontal transbasal approach can then be combined with an endoscopic endonasal approach (EEA) from below. This article reviews the indications, surgical technique, and operative nuances of combined transbasal and EEA (cranionasal) approaches for the surgical management of ventral skull base malignancies...
April 2017: Otolaryngologic Clinics of North America
journal
journal
21897
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"