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Respiration; International Review of Thoracic Diseases

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https://www.readbyqxmd.com/read/29920503/prognosis-of-interstitial-lung-disease-associated-with-anti-aminoacyl-trna-synthetase-antibodies-look-in-the-middle
#1
Vasilios Tzilas, Argyris Tzouvelekis, Evangelos Bouros, Demosthenes Bouros
No abstract text is available yet for this article.
June 19, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29909420/neopterin-as-a-biomarker-in-patients-with-pulmonary-arterial-hypertension-and-chronic-thromboembolic-pulmonary-hypertension
#2
Anna Smukowska-Gorynia, Justyna Marcinkowska, Ewa Chmara, Katarzyna Malaczynska-Rajpold, Sylwia Slawek-Szmyt, Artur Cieslewicz, Magdalena Janus, Aleksander Araszkiewicz, Stanislaw Jankiewicz, Anna Komosa, Anna Olasinska-Wisniewska, Iga Tomaszewska, Tatiana Mularek-Kubzdela
BACKGROUND: Upregulation of the immune system is regarded to play an important role in the etiopathobiology of pulmonary arterial hypertension (PAH) and inoperable chronic thromboembolic pulmonary hypertension (CTEPH). To the best of our knowledge, neopterin (NP) has never been investigated in patients with PAH and CTEPH. OBJECTIVES: The aim of the study was to evaluate the concentration of NP in blood in order to examine its impact on outcome and relationship with disease severity in that population...
June 15, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29902795/chest-drain-fall-out-rate-according-to-suturing-practices-a-retrospective-direct-comparison
#3
Rachelle Asciak, Dinesh Addala, Juzer Karimjee, Maaz Suhail Rana, Stamatoula Tsikrika, Maged Fayed Hassan, Rachel Mary Mercer, Robert John Hallifax, John Matthew Wrightson, Ioannis Psallidas, Rachel Benamore, Najib Mahboob Rahman
BACKGROUND: Chest drains often become displaced and require replacement, adding unnecessary risks to patients. Simple measures such as suturing of the drain may reduce fall-out rates; however, there is no direct data to demonstrate this and no standardized recommended practice that is evidence based. OBJECTIVES: The study aimed to analyze the rate of chest drain fall out according to suturing practice. METHODS: Retrospective analysis of all chest drain insertions (radiology and pleural teams) in 2015-2016...
June 14, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29898461/molecular-nodal-staging-using-mirna-expression-in-lung-cancer-patients-by-endobronchial-ultrasound-guided-transbronchial-needle-aspiration
#4
Terunaga Inage, Takahiro Nakajima, Sakae Itoga, Takayuki Ishige, Taiki Fujiwara, Yuichi Sakairi, Hironobu Wada, Hidemi Suzuki, Takekazu Iwata, Masako Chiyo, Shigetoshi Yoshida, Kazuyuki Matsushita, Kazuhiro Yasufuku, Ichiro Yoshino
BACKGROUND: The limited negative predictive value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has often been discussed. OBJECTIVE: The aim of this study was to identify a highly sensitive molecular biomarker for lymph node staging by EBUS-TBNA. METHODS: Five microRNAs (miRNAs) (miR-200a, miR-200b, miR-200c, miR-141, and let-7e) were selected as biomarker candidates for the detection of nodal metastasis in a miRNA expression analysis...
June 13, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29895029/bronchoscopic-thermal-vapor-ablation-best-practice-recommendations-from-an-expert-panel-on-endoscopic-lung-volume-reduction
#5
Daniela Gompelmann, Pallav L Shah, Arschang Valipour, Felix J F Herth
Bronchoscopic thermal vapor ablation (BTVA) represents one of the endoscopic lung volume reduction (ELVR) techniques that aims at hyperinflation reduction in patients with advanced emphysema to improve respiratory mechanics. By targeted segmental vapor ablation, an inflammatory response leads to tissue and volume reduction of the most diseased emphysematous segments. So far, BTVA has been demonstrated in several single-arm trials and 1 multinational randomized controlled trial to improve lung function, exercise capacity, and quality of life in patients with upper lobe-predominant emphysema irrespective of the collateral ventilation...
June 12, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29894993/transbronchial-lung-cryobiopsy-in-interstitial-lung-diseases-best-practice
#6
Sara Colella, Maik Haentschel, Pallav Shah, Venerino Poletti, Jürgen Hetzel
The lung biopsy in interstitial lung disease (ILD) represents an important diagnostic step when the clinical and radiological data are insufficient for a firm diagnosis. A growing body of evidence suggests the utility of transbronchial lung cryobiopsy (TBLC) in the diagnostic algorithm of ILD as it allows, compared to transbronchial lung biopsy with conventional forceps, a better identification of complex histological patterns - such as usual interstitial pneumonia - and can provide information which has a clinical impact on the multidisciplinary discussion similar to that provided by surgical lung biopsy...
June 12, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29874679/breathlessness-and-restrictive-lung-disease-an-important-diabetes-related-feature-in-patients-with-type-2-diabetes
#7
Stefan Kopf, Jan B Groener, Zoltan Kender, Thomas Fleming, Maik Brune, Christin Riedinger, Nadine Volk, Esther Herpel, Dominik Pesta, Julia Szendrödi, Mark O Wielpütz, Hans-Ulrich Kauczor, Hugo A Katus, Michael Kreuter, Peter P Nawroth
BACKGROUND: Diabetes mellitus is a significant comorbidity of interstitial lung disease (ILD). OBJECTIVES: The aim of this study was to investigate the incidence of restrictive lung disease (RLD) and ILD in patients with prediabetes and type 2 diabetes (T2D). METHODS: Forty-eight nondiabetics, 68 patients with prediabetes, 29 newly diagnosed T2D, and 110 patients with long-term T2D were examined for metabolic control, diabetes-related complications, breathlessness, and lung function...
June 6, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29791901/exeunt-lateral-decubitus-radiographs
#8
Jane A Shaw, Coenraad F N Koegelenberg
No abstract text is available yet for this article.
May 23, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29772571/effect-of-air-pollution-on-exacerbations-of-bronchiectasis-in-badalona-spain-2008-2016
#9
Ignasi Garcia-Olivé, Zoran Stojanovic, Joaquim Radua, Laura Rodriguez-Pons, Carlos Martinez-Rivera, Juan Ruiz Manzano
INTRODUCTION: Air pollution has been widely associated with respiratory diseases. Nevertheless, the association between air pollution and exacerbations of bronchiectasis has been less studied. OBJECTIVE: To analyze the effect of air pollution on exacerbations of bronchiectasis. METHODS: This was a retrospective observational study conducted in Badalona. The number of daily hospital admissions and emergency room visits related to exacerbation of bronchiectasis (ICD-9 code 494...
May 17, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29768275/predictive-factors-for-the-long-term-deterioration-of-pulmonary-function-in-interstitial-lung-disease-associated-with-anti-aminoacyl-trna-synthetase-antibodies
#10
Hideaki Yamakawa, Eri Hagiwara, Hideya Kitamura, Tae Iwasawa, Ryota Otoshi, Naoto Aiko, Takuma Katano, Ryota Shintani, Satoshi Ikeda, Ryo Okuda, Akimasa Sekine, Tomohisa Baba, Shinichiro Iso, Kazuyoshi Kuwano, Shinji Sato, Takashi Ogura
BACKGROUND: Little has been reported on long-term pulmonary function trends among patients with interstitial lung disease associated with anti-aminoacyl-tRNA synthetase antibodies (ARS-ILD). OBJECTIVES: To clarify the factors predictive of progression in ARS-ILD based on patients' initial clinical and radiological features. METHODS: The clinical courses of 88 patients with > 1 year of follow-up data on pulmonary function tests (PFTs) were retrospectively analyzed...
May 16, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29763900/c-prosp-b-a-possible-biomarker-for-pulmonary-diseases
#11
Nicolas Kahn, Anne-Kathrin Rossler, Katrin Hornemann, Thomas Muley, Ekkehard Grünig, Werner Schmidt, Felix J F Herth, Michael Kreuter
BACKGROUND: Detection of surfactant proteins A and D (SP-A and SP-D) in the serum of patients with pulmonary diseases is thought to reflect an injury of the alveolar epithelial barrier and as such serve as a biomarker for these diseases. However, the data for SP-B are limited. OBJECTIVES: The aim of this feasibility study was to assess whether immature SP-B pre-proteins might have value as a possible biomarker for pulmonary diseases. METHODS: In serum samples from patients with different chronic lung diseases (interstitial lung diseases [ILDs], chronic obstructive pulmonary disease, asthma, lung cancer, pulmonary hypertension, inflammation, patients on ventilator support; total n = 283), C-proSP-B was measured using an electrochemiluminescence immunoassay based on mouse monoclonal anti-C-proSP-B antibodies...
May 15, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29739002/-unknown-title
#12
(no author information available yet)
No abstract text is available yet for this article.
May 8, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29730665/associations-between-dietary-patterns-and-post-bronchodilation-lung-function-in-the-sapaldia-cohort
#13
Nina Steinemann, Leticia Grize, Marco Pons, Thomas Rothe, Daiana Stolz, Alexander Turk, Christian Schindler, Christine Brombach, Nicole Probst-Hensch
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is not restricted to smokers. Dietary habits may contribute to the disease occurrence. Epidemiological studies point to a protective effect of fruit and vegetable intake against COPD. OBJECTIVE: To investigate the associations between dietary patterns and parameters of lung function related to COPD in the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). METHODS: Data were included from the second follow-up assessment of the SAPALDIA cohort in 2010-2011 using a food frequency questionnaire...
May 4, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29723854/diagnostic-accuracy-of-lateral-decubitus-chest-radiography-before-pleural-maneuvers-for-the-management-of-pleurisies-in-the-era-of-chest-ultrasound
#14
Khady Thiam, Julie Berbis, Sophie Laroumagne, Julien Guinde, Bertrand Chollet, Hervé Dutau, Nafissatou O Touré, Philippe Astoul
BACKGROUND: Chest ultrasound (CUS) is the gold standard to detect pleural adhesions before pleural maneuvers. However, the CUS technique is not available in all countries where the assessment is only based on clinical examination and chest radiography. OBJECTIVE: To assess the value of lateral decubitus chest radiography (LDCR) to detect pleural adhesions. METHODS: Consecutive patients with pleural effusions undergoing LCDR followed by medical thoracoscopy the day after were identified from an institutional database...
May 3, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29719298/mesenchymal-stromal-cells-to-regenerate-emphysema-on-the-horizon
#15
Dennis M L W Kruk, Irene H Heijink, Dirk-Jan Slebos, Wim Timens, Nick H Ten Hacken
Mesenchymal stem or stromal cells (MSCs) are multipotent cells that play a pivotal role in various phases of lung development and lung homeostasis, and potentially also lung regeneration. MSCs do not only self-renew and differentiate into renew tissues, but also have anti-inflammatory and paracrine properties to reduce damage and to support tissue regeneration, constituting a promising cell-based treatment strategy for the repair of damaged alveolar tissue in emphysema. This review discusses the current state of the art regarding the potential of MSCs for the treatment of emphysema...
May 2, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29694986/-kissing-nodules-in-saber-sheath-trachea
#16
Julien Guinde, Samer Georges, Valerian Bourinet, Sophie Laroumagne, Philippe Astoul, Hervé Dutau
No abstract text is available yet for this article.
April 25, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29694983/nintedanib-in-severe-idiopathic-pulmonary-fibrosis-effectiveness-through-compassion
#17
Argyrios Tzouvelekis, Demosthenes Bouros
No abstract text is available yet for this article.
April 25, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29680830/pulmonary-perfusion-using-intrabronchial-capnography-in-pulmonary-artery-stenosis
#18
Hiroki Nishine, Hiromi Muraoka, Takeo Inoue, Teruomi Miyazawa, Masamichi Mineshita
Stenting at the flow-limiting segment can improve the ventilation-perfusion ratio in patients with central airway stenosis. However, there is no quantitative examination for assessing the perfusion status during interventional bronchoscopy. Intrabronchial capnography can estimate regional gas exchange by measuring carbon dioxide concentration. We herein report a case of bilateral bronchial stenosis where stenting was able to improve ventilation-perfusion ratio using intrabronchial capnography. A 44-year-old man was admitted to our institution with orthopnea...
April 20, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29642071/risk-factor-profiles-achieved-with-medical-therapy-in-prevalent-patients-with-pulmonary-arterial-and-distal-chronic-thromboembolic-pulmonary-hypertension
#19
Philipp Bartenstein, Stéphanie Saxer, Paula Appenzeller, Mona Lichtblau, Esther I Schwarz, Silvia Ulrich
BACKGROUND: The latest pulmonary hypertension (PH) guidelines define therapeutic goals in terms of symptoms, exercise capacity, and haemodynamics for patients with pulmonary arterial hypertension (PAH) and recommend advanced combined medical therapy. For inoperable or post-surgical residual distal chronic thromboembolic PH (CTEPH) medical treatment is similarly advised. OBJECTIVES: We analysed whether risk factor goals are achieved and combination therapy is used in prevalent patients with PAH or distal CTEPH...
April 11, 2018: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29635251/clinical-diagnostic-and-treatment-disparities-between-hiv-infected-and-non-hiv-infected-immunocompromised-patients-with-pneumocystis-jirovecii-pneumonia
#20
Helmut J F Salzer, Guido Schäfer, Martin Hoenigl, Gunar Günther, Christian Hoffmann, Barbara Kalsdorf, Alexandre Alanio, Christoph Lange
The substantial decline in the Pneumocystis jirovecii pneumonia (PCP) incidence in HIV-infected patients after the introduction of antiretroviral therapy (ART) in resource-rich settings and the growing number of non-HIV-infected immunocompromised patients at risk leads to considerable epidemiologic changes with clinical, diagnostic, and treatment consequences for physicians. HIV-infected patients usually develop a subacute course of disease, while non-HIV-infected immunocompromised patients are characterized by a rapid disease progression with higher risk of respiratory failure and higher mortality...
April 10, 2018: Respiration; International Review of Thoracic Diseases
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