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Respiration; International Review of Thoracic Diseases

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https://www.readbyqxmd.com/read/29045951/lifestyle-behaviors-and-clinical-outcomes-in-idiopathic-pulmonary-fibrosis
#1
Baruch Vainshelboim, Jose Oliveira, Shimon Izhakian, Avraham Unterman, Mordechai Reuven Kramer
BACKGROUND: Lifestyle behaviors are not well-characterized in idiopathic pulmonary fibrosis (IPF). OBJECTIVES: To assess the association between lifestyle behaviors and clinical outcomes in patients with IPF. METHODS: A total of 34 IPF patients (median age 68 years) were assessed for daily sitting and weekly walking times using the International Physical Activity Questionnaire by in-person interview at baseline, and they were followed up for up to 40 months...
October 19, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29045949/effectiveness-of-a-home-based-active-video-game-programme-in-young-cystic-fibrosis-patients
#2
Tamara Del Corral, Maria Àngels Cebrià I Iranzo, Ibai López-de-Uralde-Villanueva, Roberto Martínez-Alejos, Isabel Blanco, Jordi Vilaró
BACKGROUND: Exercise-based rehabilitation is already a part of cystic fibrosis (CF) treatment; however, patient adherence is low. OBJECTIVES: To assess the effectiveness of a home exercise programme using active video games (AVGs) as a training modality for children and adolescents with CF. METHODS: Thirty-nine children with CF were randomised to a control group (CG, n = 20, age 11 ± 6 years; FEV1 86.2 ± 20.5% of predicted) or a training group (AVGG, n = 19, age 13 ± 3 years; FEV1 82...
October 19, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29024926/metsovo-lung-a-story-of-episteme-techne-and-phronesis
#3
Vasilios Tzilas, Argyris Tzouvelekis, Demosthenes Bouros
No abstract text is available yet for this article.
October 13, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29020679/a-preclinical-evaluation-comparing-the-performance-of-a-novel-19-g-flexible-needle-to-a-commercially-available-22-g-ebus-tbna-sampling-needle
#4
Kasia Czarnecka-Kujawa, Alain Tremblay, Kazuhiro Yasufuku, Anna Sczaniecka, Sujeeth Parthiban, Lawrence Kunz, David Dillard, Xavier Gonzalez
BACKGROUND: Needle samples may not provide sufficient diagnostic material for the assessment of mediastinal lymph nodes. OBJECTIVE: The study compared the specimen size and diagnostic performance of a new 19-G endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) needle to that of a standard 22-G EBUS-TBNA needle in a swine model of granulomatous lymphadenopathy. METHODS: Granulomatous inflammation was induced in mediastinal lymph nodes (LNs) of 10 domestic swine by injection of talc slurry...
October 12, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29020675/increased-platelet-monocyte-interaction-in-stable-copd-in-the-absence-of-platelet-hyper-reactivity
#5
Floor E Aleva, Godfrey Temba, Quirijn de Mast, Sami O Simons, Philip G de Groot, Yvonne F Heijdra, André J A M van der Ven
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is well known for its cardiovascular co-morbidities. Increased platelet-monocyte interaction is found in COPD and may reflect altered platelet function and a potential role for anti-platelet therapy. OBJECTIVES: The objectives were to investigate platelet-monocyte interaction, platelet activation and reactivity and plasmatic coagulation in stable COPD. METHODS: Platelet-monocyte interaction and platelet activation were determined by flow cytometry in 30 stable COPD patients and 25 controls...
October 12, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29020669/evidence-suggesting-the-end-of-universal-domestic-asbestos-exposure-in-metsovo-nw-greece
#6
Athena Gogali, Evangelia E Ntzani, Carmen Manda-Stachouli, Sofia Peristeri, Loukia Tzarouchi, Elpiniki Laiou, Athanasios Konstantinidis, Stavros H Constantopoulos, Yotanna Dalavanga
BACKGROUND: Inhabitants of Metsovo, NW Greece, had been domestically exposed to asbestos from a gradually abandoned whitewash ("luto") that resulted in a declining epidemic of malignant mesothelioma. OBJECTIVES: We aimed to evaluate whether other sources of asbestos exposure exist following "luto" abandonment. METHODS: Chest computed tomography (CT) and bronchoalveolar lavage (BAL) were used to evaluate residual asbestos exposure in younger Metsovites through the identification of pleural calcifications and asbestos bodies, respectively...
October 12, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28977804/vascular-dynamics-and-peripheral-oxygen-uptake-in-obese-individuals-during-progressive-physical-exercise
#7
Amelia Brunani, Stefano Lanzi, Franco Codecasa, Mauro Cornacchia, Sabrina Maestrini, Davide Soranna, Antonella Zambon, Stefania Cattaldo, Paolo Fanari, Davide Malatesta, Alberto Salvadori
BACKGROUND: Obese men show higher O2 consumption than lean men during physical exercise, with a trend toward higher peripheral O2 extraction; this is probably due to their larger muscle mass. OBJECTIVES: The aim of this study was to examine this phenomenon by measuring 2 vasoactive substances, endothelin-1 (ET-1) and nitric oxide (NO), during a progressive submaximal exercise. METHODS: Seventeen obese (body mass index [BMI] 38.6) and 15 lean (BMI 22...
October 5, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28950263/on-the-relation-of-pseudomonas-aeruginosa-infection-and-respiratory-muscle-function-in-adolescents-and-adults-with-cystic-fibrosis
#8
Theodore Dassios, Gabriel Dimitriou
No abstract text is available yet for this article.
September 27, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28918427/safety-of-monitored-anesthesia-care-using-propofol-based-sedation-for-pleuroscopy
#9
Erik Vakil, Mona Sarkiss, David Ost, Macarena R Vial, Roberto F Casal, Georgie A Eapen, Horiana B Grosu
BACKGROUND: The optimal approach to sedation for pleuroscopy remains undefined. Propofol is the favored sedative-hypnotic for many proceduralists but has a narrow therapeutic window and the risk for oversedation is high. Propofol-based sedation administered by anesthesiologists and the routine use of end-tidal capnography and bispectral index (BIS) monitoring may attenuate risks of complications. OBJECTIVES: The purpose of our study was to evaluate the safety and efficacy of monitored anesthesia care for pleuroscopy...
September 16, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28918422/the-modern-art-of-reading-computed-tomography-images-of-the-lungs-quantitative-ct
#10
Felix J F Herth, Miranda Kirby, Jered Sieren, Jonas Herth, Joshua Schirm, Susan Wood, Maren Schuhmann
Lung diseases are increasing in prevalence and overall burden worldwide. To stem the tide, more and more national and international guidelines are recommending the use of various diagnostic algorithms that are disease specific. There is growing consensus among the respiratory community that although patient histories and lung function testing are the minimum required for clinical examinations, these tests alone are not sufficient for disease characterization. Therefore, the use of computed tomography (CT) imaging is increasing used in clinical decision making for lung diseases...
September 16, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28910816/mediastinal-and-subcutaneous-chest-fat-are-differentially-associated-with-emphysema-progression-and-clinical-outcomes-in-smokers
#11
Jon Grace, Joseph K Leader, Seyed M Nouraie, Jiantao Pu, Divay Chandra, Yingze Zhang, Frank C Sciurba, Jessica Bon
BACKGROUND: Studies have demonstrated both positive and negative effects of obesity on clinical outcomes in chronic obstructive pulmonary disease (COPD). In other chronic diseases, fat location is differentially associated with disease outcomes; however, this relationship has not been well studied in COPD. OBJECTIVE: To determine if fat location explains the differential association of body mass index (BMI) with clinical outcome measures in smokers. METHODS: Baseline and 6-year chest computed tomography scans from 68 current and former smokers were used to quantify mediastinal and subcutaneous fat...
September 15, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28910804/ebus-tbna-can-distinguish-sarcoid-like-side-effect-of-nivolumab-treatment-from-tumor-progression-in-non-small-cell-lung-cancer
#12
Ségolène Lainez, Claire Tissot, Michèle Cottier, Jean-Michel Vergnon
With the expansion of immunotherapy in the treatment of lung cancer, clinicians have to face new clinical pictures and adapt their practice. We report the case of a 69-year-old man diagnosed with non-small cell lung cancer using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and treated with nivolumab as second-line therapy. After 8 injections of nivolumab, a new CT and PET scan revealed massive growth and increase in metabolism of hilar and mediastinal lymph nodes, whereas the size and metabolism of the left upper lobe lesion were reduced...
September 15, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28881352/current-practice-of-airway-stenting-in-the-adult-population-in-europe-a-survey-of-the-european-association-of-bronchology-and-interventional-pulmonology-eabip
#13
Hervé Dutau, David Breen, Antonio Bugalho, Levent Dalar, Johannes Daniels, Christophe Dooms, Ralf Eberhardt, Lars Ek, Milena Encheva, Michel Febvre, Martin Hackl, Sirje Marran, Zsolt Papai-Szekely, Michael Perch, Mihovil Roglic, Antoni Rosell, Ales Rozman, Pallav L Shah, Marioara Simon, Artur Szlubowski, Grigoris Stratakos, Arve Sundset, Toomas Uibu, Christophe Von Garnier, Bojan Zaric, Marija Zdraveska, Lina Zuccatosta, Darijo Bokan, Syed Arshad Husain, Semra Bilaceroglu, Paola Gasche-Soccal, Stefano Gasparini, Felix J F Herth, Muhammed Munavvar
BACKGROUND: Airway stenting (AS) commenced in Europe circa 1987 with the first placement of a dedicated silicone airway stent. Subsequently, over the last 3 decades, AS was spread throughout Europe, using different insertion techniques and different types of stents. OBJECTIVES: This study is an international survey conducted by the European Association of Bronchology and Interventional Pulmonology (EABIP) focusing on AS practice within 26 European countries. METHODS: A questionnaire was sent to all EABIP National Delegates in February 2015...
September 8, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28869942/pulmonary-cavities-after-diagnostic-transbronchial-cryobiopsy-in-a-lung-transplantation-patient
#14
Rebeca Sicilia Torres, Felipe Rodríguez de Castro, Carlos Cabrera López, Gabriel Juliá Serdá, Fernando Rezola Sáez, Rubén Pestana
No abstract text is available yet for this article.
September 5, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28787715/safety-and-efficacy-of-immunoadsorption-as-an-add-on-to-medical-treatment-in-patients-with-severe-idiopathic-pulmonary-arterial-hypertension
#15
Christian Nagel, Ralf Ewert, Benjamin Egenlauf, Hans B Lehmkuhl, Stephan Rosenkranz, Nicola Benjamin, Vedat Schwenger, Felix J F Herth, Ekkehard Grünig
BACKGROUND: Despite optimized medical therapy, severe idiopathic pulmonary arterial hypertension (IPAH) is a devastating disease with a poor outcome. Autoantibodies have been detected in IPAH that can contribute to worsening of the disease. OBJECTIVES: The objective of this prospective, open-label, single-arm, multicenter trial was to evaluate the safety and efficacy of immunoadsorption (IA) as an add-on to optimized medical treatment for patients with IPAH. METHODS: A total of 10 IPAH patients received IA over 5 days...
August 5, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28743113/pulmonary-hypertension-in-a-large-cohort-with-hereditary-hemorrhagic-telangiectasia
#16
Veronique Vorselaars, Sebastiaan Velthuis, Marco van Gent, Cornelis Westermann, Repke Snijder, Johannes Mager, Martijn Post
BACKGROUND: Hereditary hemorrhagic telangiectasia (HHT) is a vascular disorder characterized by arteriovenous malformations in the brain, liver, and lungs. Pulmonary hypertension (PH) is increasingly recognized as a severe complication of HHT. However, there are no studies describing the prevalence of PH in HHT compared to HHT-negative controls. OBJECTIVE: To assess the estimated prevalence of PH in patients with HHT compared to HHT-negative controls. METHODS: All consecutive subjects screened for HHT with available genetic testing and echocardiography-based peak tricuspid regurgitation velocity (TRV) measurement were included...
July 26, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28738364/risk-factors-for-community-acquired-pneumonia-in-adults-a-systematic-review-of-observational-studies
#17
Jordi Almirall, Mateu Serra-Prat, Ignasi Bolíbar, Valentina Balasso
We performed a systematic review of the literature to establish conclusive evidence of risk factors for community-acquired pneumonia (CAP). Observational studies (cross-sectional, case-control, and cohort studies) the primary outcome of which was to assess risk factors for CAP in both hospitalized and ambulatory adult patients with radiologically confirmed pneumonia were selected. The Newcastle-Ottawa Scale specific for cohort and case-control designs was used for quality assessment. Twenty-nine studies (20 case-control, 8 cohort, and 1 cross-sectional) were selected, with 44...
July 25, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28738386/exercise-capacity-impairment-can-predict-postoperative-pulmonary-complications-after-liver-transplantation
#18
Clarissa Bentes de Araújo Magalhães, Ingrid Correia Nogueira, Liegina Silveira Marinho, Elizabeth F Daher, José Huygens P Garcia, Cyntia F G Viana, Pedro Felipe Carvalhedo de Bruin, Eanes Delgado Barros Pereira
BACKGROUND: Postoperative respiratory complications (PRCs) are common after liver transplantation (LT) and contribute significantly to the related morbidity and mortality. OBJECTIVE: The aim of this paper was to determine the incidence of PRCs after LT and the value of simple exercise capacity measures as independent predictors of PRCs. METHODS: We conducted a prospective cohort study of consecutive adults submitted to LT at a University Hospital in Fortaleza Brazil from March 2013 to March 2015...
July 22, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28738339/lung-ultrasound-b-lines-etiologies-and-evolution-with-age
#19
Giuseppe Francesco Sferrazza Papa, Giulia Michela Pellegrino, Giovanni Volpicelli, Simone Sferrazza Papa, Fabiano Di Marco, Michele Mondoni, Stefano Centanni
No abstract text is available yet for this article.
July 22, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28719911/dissecting-survival-pathways-in-lung-cancer-fibrosis-and-emphysema-the-four-horses-of-the-apocalypse
#20
Argyris Tzouvelekis, Vasilios Tzilas, Spyridon Papiris, Demosthenes Bouros
No abstract text is available yet for this article.
July 19, 2017: Respiration; International Review of Thoracic Diseases
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