Fiona S L Brinkman, Geoffrey L Winsor, Rachel E Done, Alain Filloux, Vanessa I Francis, Joanna B Goldberg, E Peter Greenberg, Kook Han, Robert E W Hancock, Cara H Haney, Susanne Häußler, Jens Klockgether, Iain L Lamont, Roger C Levesque, Stephen Lory, Pablo I Nikel, Steven L Porter, Matthew W Scurlock, Herbert P Schweizer, Burkhard Tümmler, Meng Wang, Martin Welch
Toward the end of August 2000, the 6.3 Mbp whole genome sequence of Pseudomonas aeruginosa strain PAO1 was published. With 5570 open reading frames (ORFs), PAO1 had the largest microbial genome sequenced up to that point in time-including a large proportion of metabolic, transport and antimicrobial resistance genes supporting its ability to colonize diverse environments. A remarkable 9% of its ORFs were predicted to encode proteins with regulatory functions, providing new insight into bacterial network complexity as a function of network size...
2021: Advances in Microbial Physiology