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Archives of Oral Biology

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https://www.readbyqxmd.com/read/28335991/corrigendum-to-saliva-initiates-the-formation-of-pro-inflammatory-macrophages-in-vitro-arch-oral-biol-73-january-2017-295-301
#1
Solmaz Pourgonabadi, Heinz-Dieter Müller, João Rui Mendes, Reinhard Gruber
No abstract text is available yet for this article.
March 20, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28340422/the-clinicopathologic-relevance-of-reck-gene-polymorphisms-in-ameloblastoma
#2
Xudong Zhang, Jie Wang, Huijuan Liu, Yanning Zhang, Fusheng Dong
OBJECTIVE: To investigate the relationship between RECK gene polymorphisms and the clinicopathologic features of ameloblastoma. DESIGN: Normal gingival mucosa specimens were obtained from 10 healthy volunteers. Ameloblastomas were surgically removed from 30 patients and part of the tumor specimens were used to detect RECK gene polymorphisms by using PCR-single-strand conformation polymorphism (PCR-SSCP) and DNA sequencing analysis. Expression of RECK and MMP-9 protein was measured using western blot...
March 16, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28350992/expression-of-circadian-core-clock-genes-in-fibroblasts-of-human-gingiva-and-periodontal-ligament-is-modulated-by-l-mimosine-and-hypoxia-in-monolayer-and-spheroid-cultures
#3
Klara Janjić, Christoph Kurzmann, Andreas Moritz, Hermann Agis
OBJECTIVE: The circadian clock is involved in a plethora of physiological processes including bone formation and tooth development. While expression of circadian core clock genes was observed in various tissues, their role in the periodontium is unclear. We hypothesized that periodontal cells express circadian core clock genes and that their levels are modulated by hypoxia mimetic agents and hypoxia. MATERIAL AND METHODS: Fibroblasts of human gingiva (GF) and periodontal ligament (PDLF) in monolayer and spheroid cultures were treated with the hypoxia mimetic agent L-Mimosine (L-MIM) or hypoxia...
March 14, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28292674/the-anti-oxidant-effects-of-melatonin-derivatives-on-human-gingival-fibroblasts
#4
Chawapon Phiphatwatcharaded, Ploenthip Puthongking, Ponlatham Chaiyarit, Nutjaree Pratheepawanit Johns, Sumon Sakolchai, Pramote Mahakunakorn
OBJECTIVES: Aim of this in vitro study was to evaluate the anti-oxidant activity of indole ring modified melatonin derivatives as compared with melatonin in primary human gingival fibroblast (HGF) cells. METHODS: Anti-oxidant activity of melatonin (MLT), acetyl-melatonin (AMLT) and benzoyl-melatonin (BMLT) was evaluated by5 standard methods as follows: 2, 2-diphenyl-1-picrylhydrazyl (DPPH); ferric ion reducing antioxidant power (FRAP); superoxide anion scavenging; nitric oxide (NO) scavenging; and thiobarbituric acid reactive substances (TBARs)...
March 7, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28301818/distribution-of-hemokinin-1-in-the-rat-trigeminal-ganglion-and-trigeminal-sensory-nuclear-complex
#5
Kaori Igawa, Hideki Funahashi, Yu Miyahara, Rumi Naono-Nakayama, Hisae Matsuo, Yoshihiro Yamashita, Sumio Sakoda, Toshikazu Nishimori, Yasushi Ishida
OBJECTIVE: A new mammalian tachykinin peptide encoded in a TAC4 gene was identified and designated as hemokinin-1 (HK-1). A representative of the tachykinin peptide family is substance P (SP), and the function of SP has been well characterized as a pain transmitter or modulator, while it is possible that HK-1 is involved in pruriceptive processing, but, as yet, the distribution of HK-1 peptide in the trigeminal sensory system is still unknown. Thus, the aim of the present study was to elucidate the distribution of HK-1, while comparing the expression of SP, in the trigeminal ganglion and trigeminal sensory nuclear complex...
March 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28288391/evidence-of-phenotypic-stability-after-transduction-of-fluorescent-proteins-in-two-human-tongue-cancer-cell-lines
#6
Wei-Xin Cai, Li-Wu Zheng, Hong-Zhang Huang, Roger A Zwahlen
OBJECTIVES: This study investigated the phenotypic stability and biological properties of two human tongue cancer cell lines after transduction of fluorescent proteins. DESIGN: The human tongue cancer cell lines UM1 and UM2 were cultured with GFP and RFP lentiviral particles stock for 72h. Cells with successful transduction of fluorescent proteins were selected in a medium containing G418 antibiotics for two weeks. The proliferation rates of parental and transduced cell lines were evaluated by their population doubling time (PDT)...
March 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28285126/expression-of-neprilysin-in-periodontitis-affected-gingival-tissues
#7
A Nezu, T Kubota, S Maruyama, M Nagata, K Nohno, T Morozumi, H Yoshie
OBJECTIVE: Although the pathogeneses of Alzheimer's disease (AD) and periodontal diseases have overlapping features, including ageing and chronic inflammation, the association between AD and periodontitis remains unclear. To explore the pathogenesis of periodontitis, a comprehensive gene expression/transcriptome analysis in periodontitis-affected gingival tissues found that the AD pathway was significantly up-regulated in periodontitis-affected gingival tissues. AD-related genes, amyloid beta precursor protein (APP), interleukin-1 beta and compliment 1QA, were significantly elevated in periodontitis...
March 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28282513/the-local-administration-of-parathyroid-hormone-encourages-the-healing-of-bone-defects-in-the-rat-calvaria-micro-computed-tomography-histological-and-histomorphometric-evaluation
#8
Caroline Moreira Auersvald, Felipe Rychuv Santos, Mayara Mytie Nakano, Graziela Bianchi Leoni, Manoel Damião de Sousa Neto, Rafaela Scariot, Allan Fernando Giovanini, Tatiana Miranda Deliberador
OBJECTIVE: To evaluate the effect of a single-dose local administration of PTH on bone healing in rat calvarial bone defects by means of micro-computed tomography, histological and histomorphometric analysis. DESIGN: Critical-size cranial osteotomy defects were created in 42 male rats. The animals were randomly divided into 3 groups. In the C Group, the bone defect was only filled with a blood clot. In the S Group, it was filled with a collagen sponge and covered with bovine cortical membrane...
March 6, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28282514/the-proteomic-profile-of-the-acquired-enamel-pellicle-according-to-its-location-in-the-dental-arches
#9
Talita Mendes da Silva Ventura, Luiza de Paula Silva Cassiano, Cíntia Maria de Souza E Silva, Even Akemi Taira, Aline de Lima Leite, Daniela Rios, Marília Afonso Rabelo Buzalaf
OBJECTIVE: This study evaluated the variation in the protein profile of the acquired enamel pellicle (AEP) formed in vivo according to its location in the dental arches. DESIGN: The AEP was formed for 120min in 9 volunteers. Pellicle formed at upper+lower anterior facial (ULAFa; teeth 13-23 and 33-43), upper anterior palatal (UAPa; teeth 13-23), lower anterior lingual (LALi; teeth 33-43), upper+lower posterior facial (ULPFa; teeth 14-17 24-27, 34-37 and 44-47), upper posterior palatal (UPPa; teeth 14-17 and 24-27) and lower posterior lingual (LPLi; teeth 34-37 and 44-47) regions were collected separately and processed for analysis by label-free LC-ESI-MS/MS...
March 3, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28288390/patterns-of-non-syndromic-permanent-tooth-agenesis-in-a-large-orthodontic-population
#10
Nikolaos Gkantidis, Hattan Katib, Elias Oeschger, Marina Karamolegkou, Nikolaos Topouzelis, Georgios Kanavakis
OBJECTIVE: The aim of this study is to explore patterns of non-syndromic permanent tooth agenesis in a large orthodontic patient group. DESIGN: A record review was performed in various orthodontic clinics to identify white patients with non-syndromic permanent tooth agenesis, excluding 3rd molars. Four hundred and fourteen subjects fulfilled the inclusion criteria. RESULTS: In the 414 subjects with tooth agenesis, approximately 70% presented 1-2 missing teeth...
March 1, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28282516/f-spondin-negatively-regulates-dental-follicle-differentiation-through-the-inhibition-of-tgf-%C3%AE-activity
#11
Ai Orimoto, Misaki Kurokawa, Keisuke Handa, Masaki Ishikawa, Eisaku Nishida, Makoto Aino, Akio Mitani, Miho Ogawa, Takashi Tsuji, Masahiro Saito
OBJECTIVE: F-spondin is an extracellular matrix (ECM) protein that belongs to the thrombospondin type I repeat superfamily and is a negative regulator of bone mass. We have previously shown that f-spondin is specifically expressed in the dental follicle (DF), which gives rise to the periodontal ligament (PDL) during the tooth root formation stage. To investigate the molecular mechanism of PDL formation, we investigated the function of f-spondin in DF differentiation. DESIGN: The expression patterning of f-spondin in the developing tooth germ was compared with that of periodontal ligament-related genes, including runx2, type I collagen and periostin, by in situ hybridization analysis...
March 1, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28279824/assessment-of-gingival-biotype-and-facial-hard-soft-tissue-dimensions-in-the-maxillary-anterior-teeth-region-using-cone-beam-computed-tomography
#12
Reza Amid, Mahdieh Mirakhori, Yaser Safi, Mahdi Kadkhodazadeh, Mahshid Namdari
OBJECTIVE: This study sought to assess the relationship between facial gingival and bone dimensions in maxillary anterior teeth region using cone beam computed tomography (CBCT). DESIGN: This study assessed 621 maxillary anterior teeth in 144 patients. In the sagittal plane, facial bone thickness (BT) and gingival thickness (GT) were measured at the crestal level and at 2, 4 and 6mm apical to the cementoenamel junction (CEJ). The dentogingival complex (DGC) dimensions and the distance from the CEJ to bone crest were also measured on CBCT scans...
March 1, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28292713/transforming-growth-factor-%C3%AE-induced-gene-product-h3-inhibits-odontoblastic-differentiation-of-dental-pulp-cells
#13
Suguru Serita, Atsushi Tomokiyo, Daigaku Hasegawa, Sayuri Hamano, Hideki Sugii, Shinichiro Yoshida, Hiroyuki Mizumachi, Hiromi Mitarai, Satoshi Monnouchi, Naohisa Wada, Hidefumi Maeda
OBJECTIVE: The aim of this study was to investigate transforming growth factor-β-induced gene product-h3 (βig-h3) expression in dental pulp tissue and its effects on odontoblastic differentiation of dental pulp cells (DPCs). DESIGN: A rat direct pulp capping model was prepared using perforated rat upper first molars capped with mineral trioxide aggregate cement. Human DPCs (HDPCs) were isolated from extracted teeth. βig-h3 expression in rat dental pulp tissue and HDPCs was assessed by immunostaining...
February 24, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28282515/probiotic-consumption-decreases-the-number-of-osteoclasts-during-orthodontic-movement-in-mice
#14
Camila Alessandra Pazzini, Luciano José Pereira, Tarcília Aparecida da Silva, Carina Cristina Montalvany-Antonucci, Soraia Macari, Leandro Silva Marques, Saul Martins de Paiva
AIMS: The aim of the present study was to investigate the effect of probiotic (Bacillus Subtilis) supplementation on bone remodelling induced by mechanical loading. METHODS: C57BL/6 mice were divided in two groups: (1) Probiotic and (2) Vehicle (water). The probiotic (1.5×10(8)CFU/mL) was administered orally for 14 days, starting two days before the induction of orthodontic tooth movement (OTM). OTM was determined by histomorphometric analysis by comparing the right to the left side of the maxilla...
February 24, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28222389/correlation-between-ploidy-status-using-flow-cytometry-and-nucleolar-organizer-regions-in-benign-and-malignant-epithelial-odontogenic-tumors
#15
Sarah Ahmed Mohamed Mahmoud, Dalia Hussein El-Rouby, Safa Fathy Abd El-Ghani, Omnia Mohamed Badawy
OBJECTIVE: Differentiation between the aggressive benign odontogenic tumors and their malignant counterparts is controversial and difficult. While flow cytometry (FCM) allowed DNA analysis in neoplasia, argyrophilic organizer regions (AgNORs) number and/or size in a nucleus are correlated with the ribosomal gene activity and therefore with cellular proliferation. The aim of this research was to study the diagnostic accuracy of FCM and AgNORs staining in differentiating between benign and malignant epithelial odontogenic tumors and to correlate between these two interventions...
February 14, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28226300/from-periodontal-mechanoreceptors-to-chewing-motor-control-a-systematic-review
#16
REVIEW
Maria Grazia Piancino, Gaetano Isola, Rosangela Cannavale, Giuseppina Cutroneo, Giovanna Vermiglio, Pietro Bracco, Giuseppe Pio Anastasi
PURPOSE: This critical review summarizes the current knowledge of the structural and functional characteristics of periodontal mechanoreceptors, and understands their role in the signal pathways and functional motor control. METHOD: A systematic review of the literature was conducted. Original articles were searched through Pubmed, Cochrane Central database and Embase until january 2016. RESULT: 1466 articles were identified through database searching and screened by reviewing the abstracts...
February 13, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28237528/identification-of-potential-therapeutic-target-genes-key-mirnas-and-mechanisms-in-oral-lichen-planus-by-bioinformatics-analysis
#17
Cuihua Gong, Shangtong Sun, Bing Liu, Jing Wang, Xiaodong Chen
The study aimed to identify the potential target genes and key miRNAs as well as to explore the underlying mechanisms in the pathogenesis of oral lichen planus (OLP) by bioinformatics analysis. The microarray data of GSE38617 were downloaded from Gene Expression Omnibus (GEO) database. A total of 7 OLP and 7 normal samples were used to identify the differentially expressed genes (DEGs) and miRNAs. The DEGs were then performed functional enrichment analyses. Furthermore, DEG-miRNA network and miRNA-function network were constructed by Cytoscape software...
February 12, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28242507/increased-tumor-infiltrating-plasmacytoid-dendritic-cells-predicts-poor-prognosis-in-oral-squamous-cell-carcinoma
#18
Nannan Han, Zun Zhang, Shengwen Liu, Andrew Ow, Min Ruan, Wenjun Yang, Chenping Zhang
OBJECTIVE: Accumulating evidence suggests that plasmacytoid dendritic cells (pDC) have a dual role not only in initiating anti-tumor immune responses but also in inducing immune tolerance to facilitate cancer development. The aim of this study was to investigate the distribution and function of tumor-infiltrating pDCs in primary oral squamous cell carcinoma (OSCC) and their relation to patient outcome. METHODS: The distribution of pDCs in 10 normal oral mucosa and 60 OSCC tissues was detected by immunohistochemistry...
February 10, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28214448/effect-of-fluoride-toothpaste-with-nano-sized-trimetaphosphate-on-enamel-demineralization-an-in-vitro-study
#19
Marcelle Danelon, Juliano Pelim Pessan, Francisco Nunes Souza-Neto, Emerson Rodrigues de Camargo, Alberto Carlos Botazzo Delbem
OBJECTIVE: This study evaluated the effect of toothpastes containing 1100ppm F associated or not with micrometric or nano-sized sodium trimetaphosphate (TMP) on enamel demineralization in vitro, using a pH cycling model. DESIGN: Bovine enamel blocks (4mm×4mm, n=96) were randomly allocated into eight groups (n=12), according to the test toothpastes: Placebo (without fluoride or TMP); 1100ppm F (1100F); 1100F plus micrometric TMP at concentrations of 1%, 3% or 6%; and 1100F plus nanosized TMP at 1%, 3% or 6%...
February 10, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28222388/microbial-profile-of-dental-plaque-associated-to-white-spot-lesions-in-orthodontic-patients-immediately-after-the-bracket-removal
#20
Moniek W Beerens, Jacob M Ten Cate, Monique H van der Veen
OBJECTIVE: Denaturing Gradient Gel Electrophoresis (DGGE) is suggested to predict caries risk in young children. Such a tool would be valuable in orthodontic patients undergoing treatment with fixed appliances. In this cross-sectional study the applicability of DGGE and conventional microbiology for caries risk assessment in orthodontic patients were assessed. DESIGN: Dental plaque was obtained from orthodontic patients immediately prior to bracket removal. Presence of white spot lesions (WSL) was assessed immediately post debracketing...
February 9, 2017: Archives of Oral Biology
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