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Indian Journal of Cancer

Salima Shams, Adnan A Jabbar, Kashmira Nanji, Rafat Jan, Ambreen Tharani
Background and Aim: Cancer is a daunting illness affecting a vast number of people globally. During the illness trajectory, cancer patients suffer from physical and/or psychosocial issues. These physical and psychosocial issues demand conscious actions by patients to maintain their well-being. Hence, the objective of the pilot study was to evaluate the level of self-care behaviors and satisfaction in women suffering from cancer after exposure to supportive care (education and mind diversion activities) delivered via a patient help group program...
January 2018: Indian Journal of Cancer
Arifa Aziz, Zarka Samoon, Mohammad Khurshid, Afsheen Feroz, Nadia Ayoub, Safia Awan, Madhia Beg
Aim: There were delays reported by patients in chemotherapy administration in daycare oncology. Therefore, we decided to audit all processes which are involved in chemotherapy administration. The objective was to improve our service by decreasing the time between admission and initiation of chemotherapy and identify the reasons for delays. Materials and Methods: The audit was conducted in three parts. In Review I, audit tool was developed and information documented of 109 patients receiving chemotherapy at daycare center from April 14 to May 13, 2015...
January 2018: Indian Journal of Cancer
Ravishankar Palaniappan, Arvind Krishnamurthy, S Swaminathan Rajaraman, R Krishna Kumar
Background: Papillary carcinoma of thyroid (PTC) is a rare disease in children and adolescents and contributes to about 1.5%-3% of all pediatric malignancies. To date, no randomized trial has ever been performed in the pediatric population and management of these patients has been extrapolated from adult practice. Materials and Methods: Retrospective analysis of the patients treated for PTC in the age <21 years, between the years 1998-2013 at a tertiary cancer center from India...
January 2018: Indian Journal of Cancer
Swagnik Chakrabarti, Deepa Nair, Akshat Malik, Burhanuddin Qayyumi, Sudhir Nair, Jai Prakash Agrawal, Pankaj Chaturvedi
Background: Parotid cancers are uncommon and have a relatively long natural history. Determination of prognostic factors affecting the outcome is difficult. Materials and Methods: The primary objective was to determine the demographic, clinical, histopathology and treatment-related factors affecting overall survival (OS) in parotid cancers. The secondary objective was to study the impact of these factors on disease-free survival (DFS) and patterns of failure. Data of consecutive patients who underwent parotidectomy for primary parotid malignancy between July 2006 and April 2015 with at least 6 months of posttreatment follow-up were retrospectively retrieved...
January 2018: Indian Journal of Cancer
Deepak Dabkara, Sandip Ganguly, Bivas Biswas, Joydeep Ghosh
Background: Many agents have shown survival advantage in metastatic castrate-resistant prostate cancer (mCRPC). Despite this improvement, survival is poor, especially in subgroup of elderly patients who are not fit for cytotoxic chemotherapy. Materials and Methods: This is a single-institutional data review of mCRPC treated between December 2012 and May 2016 with oral cyclophosphamide (50-100 mg/day) ± oral prednisolone. mCRPCs failed or not fit for docetaxel and/or abiraterone were included in this study...
January 2018: Indian Journal of Cancer
Vikas Ostwal, Subhadeep Bose, Bhawna Sirohi, Bhavesh Poladia, Arvind Sahu, Prabhat Bhargava, Vipul Doshi, Rohit Dusane, Chaitali Nashikkar, Shailesh V Shrikhande, Anant Ramaswamy
Introduction: Docetaxel/oxaliplatin/capecitabine (TEX) is a commonly used combination chemotherapeutic regimen in advanced gastric cancer (AGC). Application strategies in routine clinical practice are reported in this study. Materials and Methods: Patients diagnosed with AGC, receiving biweekly TEX (docetaxel - 60 mg/m (2)-D1; oxaliplatin - 85 mg/m (2)-D1, and capecitabine 500-625 mg/m (2) orally twice daily for 14 days) between July 2012 and May 2016 were retrospectively analyzed for tolerance, prognostic factors, event-free survival (EFS), and overall survival (OS)...
January 2018: Indian Journal of Cancer
Jamal K Shakor, Atiya K Mohammed
Background: Low- and middle-income countries require to specify early detection programs and intervention models for breast cancer. The aim of this study was to assess the performance efficacy of an Iraqi early detection model in terms of cancer detection rate (CDR) and the method of participation in this program. Materials and Methods: Data from June 2007 to August 2016 was collected from the Breast Disease Treatment Center in the Sulaimani province in Iraq. A total of 40,491 women had registered at the center during that period for breast cancer screening, and cancer was detected in 793 women...
January 2018: Indian Journal of Cancer
Sangeeta Pankaj, Syed Nazneen, Simi Kumari, Anjili Kumari, Anita Kumari, Jaya Kumari, Vijayanand Choudhary, Shishir Kumar
Background: Cervical cancer is the fourth leading cause of cancer in women in the world and it is the second most common cancer in women 15-44 years of age. Strict implementation of screening programs has led to a large decrease in cervical cancer incidence and mortality in the developed countries. In contrast, cervical cancer remains largely uncontrolled in high-risk developing countries because of ineffective or no screening programs. Conventional Pap smear method has been the mainstay of most of the screening programs for many decades...
January 2018: Indian Journal of Cancer
Atia Atiq, Maria Atiq, Khalid Iqbal, Manzar A Sial, Saima Altaf, Quratul Ain Shamsi, Saeed A Buzdar
Background: RapidArc therapy, a complex form of intensity-modulated radiotherapy (IMRT), is now widely used to treat cancer patients. Aims: This study aimed to investigate and compare the plan quality of IMRT and RapidArc techniques using various dosimetric indices to find the better treatment modality for treating patients with cervix cancer. Materials and Methods: Thirteen cervical cancer patients treated with IMRT were selected for analysis and original plans were subsequently re-optimized using the RapidArc technique...
January 2018: Indian Journal of Cancer
Anita Kumari, Sangeeta Pankaj, Vijayanand Choudhary, Anjili Kumari, Syed Nazneen, Jaya Kumari, Shishir Kumar
Objective: A retrospective analysis of all patients with cancer of the cervix attending regional cancer center of Indira Gandhi Institute of Medical Sciences, Patna, from June 2015 to June 2017. The aim of this study was to know patient demographics, histology, age, stage and status of presentation, compliance with treatment and follow-up. Materials and Methods: Five hundred and eighteen consecutively registered patients with cancer of the cervix were included in the study...
January 2018: Indian Journal of Cancer
Suresh Mc Babu, Sunny Garg, Govinda Babu Kanakasetty, Lakshmaiah Chinnagiriyappa Kuntegowdanahalli, Lokanatha Dasappa, Suparna Ajit Rao
Introduction: Diffuse large B-cell lymphoma (DLBCL) is an aggressive lymphoma whose outcomes have significantly improved with rituximab in addition to anthracycline-based chemotherapy. Objective: This study aimed to study the epidemiology, treatment, and outcomes of patients with DLBCL. Materials and Methods: A total of 526 patients diagnosed with DLBCL between 2006 and 2015 were retrospectively analyzed. Results: The median age was 50 years with a male preponderance...
January 2018: Indian Journal of Cancer
Reema Shyamsunder Shukla, Yogender Aggarwal
Objective: Incidence of lung cancer (LC) is increasing day by day with exposure to smoke, radiation, and chemicals; LC is one of the leading causes of death. The major difficulty in treatment was delayed diagnosis. This study aims to propose a time-domain heart rate variability (HRV) feature-based automated system in LC prediction and its staging. Materials and Methods: HRV analysis was done using recorded electrocardiographic signal from 104 LC participants and 30 control volunteers...
January 2018: Indian Journal of Cancer
Sajid S Qureshi, Monica G Bhagat, Seema A Kembhavi, Girish Chinnaswamy, Tushar Vora, Maya Prasad, Siddarth Laskar, Nehal Khanna, Mukta R Ramadwar, Sneha Shah, Navin Salins, Sanjay Talole
Context: Pediatric solid tumors include a heterogeneous group of tumors, and the burden of these tumors, especially from resource-challenged countries, is not well described. AIMS: The aim of this study was to describe the distribution of solid tumors in children and the treatment outcome of Wilms tumor and hepatoblastoma. Patients and Methods: All patients under 15 years of age with histologically confirmed tumors presenting at a tertiary cancer center from January 2012 to December 2016 were identified from the hospital database...
January 2018: Indian Journal of Cancer
Amita Maheshwari, Neha Kumar, Sudeep Gupta, Bharat Rekhi, T S Shylasree, Rohit Dusane, Jyoti Bajpai, Jaya Ghosh, Seema Gulia, Kedar Deodhar, Santosh Menon, Palak Popat, Nilesh Sable, Meenakshi Thakur, Rajendra Kerkar
Background: Ovarian cancer is the fourth most common cancer in Indian women. Majority of these are epithelial ovarian cancers (EOCs), most of which present in advanced stage. Women with poor performance status and/or those unlikely to achieve optimal debulking at upfront surgery, benefit from neoadjuvant chemotherapy (NACT) followed by interval cytoreduction, with lesser surgical morbidity and equal survival rates as compared to primary cytoreduction. Methodology: This was a retrospective analysis of patients with advanced ovarian cancer, treated with NACT followed by interval debulking surgery at Tata Memorial Hospital from January 2014 to December 2014...
January 2018: Indian Journal of Cancer
Supriya Chopra, Meetakshi Gupta, Ashwathy Mathew, Umesh Mahantshetty, Reena Engineer, G Lavanya, Sudeep Gupta, Jaya Ghosh, Meenakshi Thakur, Kedar Deodhar, Santosh Menon, Bharat Rekhi, Jyoti Bajpai, Seema Gulia, Amita Maheshwari, Rajendra Kerkar, T S Shylasree, S K Shrivastava
Background: Cervical cancer is the second most common cancer among Indian women. This present retrospective study was conducted to report patient outcomes with locally advanced cervical cancer treated in the year 2010. Materials and Methods: Case records of cervical cancer patients registered from January 1, 2010, to December 31, 2010 were retrieved. A total of 1200 patients were registered, of which 583 received either definitive or adjuvant radiotherapy (RT). Of these, 345 patients who received complete treatment at our hospital were included for outcome analysis...
January 2018: Indian Journal of Cancer
Jyoti Bajpai, Nehal Khanna, Tushar Vora, Ashish Gulia, Siddhartha Laskar, Ajay Puri, Bhanupriya Sanduptla, Girish Chinnaswamy, Prakash Nayak, Shashikant L Juvekar, Amit Janu, Subhash Desai, Jaya Ghosh, Nilendu Purandare, Mukta Ramadwar, Venkatesh Rangarajan, Bharat Rekhi
Introduction: Primary bone and soft tissue sarcomas are rare, but diagnostically and therapeutically challenging group of tumors, requiring multidisciplinary management. There are limited documented studies from multidisciplinary teams , in the form of comprehensive analysis of these tumors, from our country. This study is an analysis of cases of osteosarcomas, Ewing sarcomas (ESs), chondrosarcomas (CSs), and soft-tissue sarcomas (STSs), registered at our institution during 2012. Methods: Clinical details, including outcomes of cases of bone and STSs, during the year 2012, were retrieved from the medical records of our institution and were further analyzed...
January 2018: Indian Journal of Cancer
Shivakumar Thiagarajan, Khuzema Fathehi, Deepa Nair, Anuja Deshmukh, Gouri Pantvaidya, Devendra Aravind Chaukar, Anil Keith D'Cruz
Background and Objectives: Salivary gland neoplasms are relatively uncommon. They have a wide variety of histopathological types with diverse biological behavior. It involves all the major and minor salivary glands in the head and neck. This article focuses on the various types of major salivary gland tumors treated at a tertiary cancer center along with their surgical morbidities and outcomes. Materials and Methods: Data of all the salivary gland neoplasms operated in the head and neck services between January 2012 and December 2013 were retrieved from a prospectively collected database...
January 2018: Indian Journal of Cancer
Anuja Deshmukh, Kranthikumar Gangiti, Gouri Pantvaidya, Deepa Nair, Sandip Basu, Devendra Chaukar, Prathamesh Pai, Sudhir Nair, Rohini Hawaldar, Rohit Dusane, Pankaj Chaturvedi, Anil D'Cruz
Background: Surgery is the mainstay in the management of thyroid cancer. Surgical outcomes need to be tempered against the excellent prognosis of the disease. Aims: This study aims to study the surgical outcomes including the 30-day morbidity and 5-year survival of thyroid cancer patients. Settings and Design: Retrospective analysis of a prospectively maintained surgical database in a tertiary cancer center in India. Materials and Methods: We analyzed 221 surgically treated patients in the year 2012...
January 2018: Indian Journal of Cancer
Nita Nair, Tanuja Shet, Vani Parmar, Rohini Havaldar, Sudeep Gupta, Ashwini Budrukkar, Rajiv Sarin, Meenakshi Thakur, Sangeeta Desai, Prabha Yadav, Rakesh Jalali, Seema Gulia, Tabassum Wadasadawala, Jaya Gosh, Jyoti Bajpai, Seema Kembhavi, Asawari Patil, Shalaka Joshi, Palak Popat, Venkatesh Rangarajan, Sneha Shah, Vaibhav Vanmali, Shabina Siddiqui, Indraneel Mittra, Rajendra Badwe
Background: Survival studies may serve as benchmarks to develop cancer-related policies and estimate baseline survival rates in a given patient population. Materials and Methods: We carried out a retrospective audit of cases managed in 2009 and now report the disease-free survival (DFS) in early breast cancer (EBC) and locally advanced breast cancer (LABC) in patients registered at a tertiary cancer center in India. Results: The study included 2192 patients with breast cancer with ages ranging from 18 years to 94 years with a median of 50 years...
January 2018: Indian Journal of Cancer
Navin Khattry, Siddhartha Laskar, Manju Sengar, Venkatesh Rangarajan, Tanuja Shet, P G Subramanian, Sridhar Epari, Bhausaheb Bagal, Jayant Sastri Goda, Archi Agarwal, Hasmukh Jain, Prashant Tembhare, Nikhil Patkar, Nehal Khanna, Sachin Punatar, Anant Gokarn, Dhanlakshmi Shetty, Hemani Jain, Avinash Bonda, Vikram Gota, Syed Hasan, Jyoti Kode, Shilpee Dutt, Suyash Kulkarni, Nitin Shetty, Nilesh Sable, Jayita Deodhar, Sunita Jadhav, Preeti Pawaskar, Libin Mathew, Hari Menon, Reena Nair, Sadhana Kannan, Shubhadha Chiplunkar, Sumeet Gujral
Introduction: There is paucity of data from India about the outcomes of patients with various hematological malignancies. Since its formation in 2009, the adult hematolymphoid disease management group of the Tata Memorial Centre is dedicated to the treatment of hematological malignancies alone. In this report, we present the outcomes of patients treated at our centre over a 5 year period for various haematological malignancies in both transplant and non-transplant setting. Methods: This is a retrospective analysis of all patients registered in adult hematolymphoid disease management group between 1st January 2010 to 31st December 2014...
January 2018: Indian Journal of Cancer
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