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Indian Journal of Cancer

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https://www.readbyqxmd.com/read/28485367/the-value-a-radiologist-brings-to-a-multidisciplinary-team-case-in-point
#1
LETTER
A Mahajan, A S Kawthalkar, N Sable, M Thakur, S Desai
No abstract text is available yet for this article.
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485366/plasma-cell-leukemia-single-institution-experience
#2
K Govind Babu, Linu Abraham Jacob, Ankit Agarwal, K C Lakshmaiah, D Lokanatha, M C Suresh Babu, L K Rajeev, K N Lokesh, A H Rudresha
BACKGROUND: The first case of plasma cell leukemia (PCL) was recognized by Gluzinski and Reichentein. It is the most aggressive among the monoclonal gammopathies. It is diagnosed by the presence of more than 20% plasma cells in the peripheral blood or an absolute plasma cell count of> 2000/mm3. Because of the relatively low incidence, most data come from case reports and retrospective studies. No prospective series have been published, and only seven reports including more than twenty patients have been identified...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485365/disclosure-of-cancer-information-among-saudi-cancer-patients
#3
A M Al-Amri
BACKGROUND: Cancer has been perceived as an incurable disease, and therefore, disclosure of cancer could harm patients. Therefore, the aim of this study was to explore Saudi cancer patients' views regarding disclosure of cancer information and the impact of gender, regions, and level of education on their desire to be disclosed of the diagnosis and prognosis. MATERIALS AND METHODS: A face-to-face interview was conducted during patient's evaluation at our hospital prior to their knowledge of being diagnosed with cancer...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485364/a-review-of-squamous-cell-carcinoma-arising-in-mature-cystic-teratoma-of-the-ovary
#4
N Abhilasha, U D Bafna, V R Pallavi, P S Rathod, S Krishnappa
INTRODUCTION: Germ cell tumors account for 20-25% of ovarian neoplasms. Mature cystic teratoma (MCT) is the most common ovarian germ cell tumor. Malignancy in MCT is seen in 1-2% of the cases. Squamous cell carcinoma (SCC) accounts for 80% of the cases and carries a poor prognosis. AIM: To study the clinicopathological factors, management protocols and its outcome. MATERIALS AND METHODS: Case records reviewed from August 2006 to August 2011 at our institute identified 10 women with SCC in ovarian MCT...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485363/study-of-efficacy-and-safety-of-modified-adjuvant-intraperitoneal-chemotherapy-regimen-in-carcinoma-ovary
#5
P Dash, V Goel, V Talwar, D C Doval, S Raina, P Goyal, A Upadhyay, N Patnaik
OBJECTIVE: It has been demonstrated in few trials that intraperitoneal and intravenous (IP/IV) chemotherapy improves survival in advanced stage ovarian cancer (OC). However, in view of high treatment-related toxicities, various modifications in treatment schedules have been tried. In this study, response and tolerability of IP paclitaxel on day 8 with IV paclitaxel on day 1 and IV cisplatin day 2 in carcinoma ovary were evaluated. PATIENTS AND METHODS: In this prospective observational study, from March 2013 to December 2015, the efficacy and tolerability of adjuvant IP/IV chemotherapy in optimally cytoreduced Stage III epithelial OC (EOC) patients were assessed...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485362/cancer-statistics-in-kamrup-urban-district-incidence-and-mortality-in-2007-2011
#6
Jagannath Dev Sharma, Amal Chandra Kataki, Debanjana Barman, Arpita Sharma, Manoj Kalita
PURPOSE: The aim of this study was to report cancer statistics in Kamrup Urban District, including incidence and, mortality. INTRODUCTION: In the last five year PBCR-Guwahati witnessed a remarkable growth in cancer incidence cases. The number of new cases of all cancer was increased from 155.3 to 188.5 and 102.7 to 165.3 per 100,000 men and women respectively from the year 2007 to 2011 in KUD. The data from KUD also have shown that for some of the specific types of cancer are highest or some of the highest incidence in rates in the world; particularly cancers of upper aero-digestive tract consist of anatomical sites such as oral cavity, hypopharynx, larynx gallbladder, stomach, lung, prostate and oesophageal cancer...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485361/second-primary-malignancy-a-retrospective-analysis-report-from-a-tertiary-cancer-center-of-north-india
#7
D Sharma, G Singh, N Kakkar, S Raj
AIM OF STUDY: We analyzed the data of second primary malignancy (SPM) from one of the tertiary cancer centers of North India, and the basic aim was to retrieve incidence, prognosis, and outcomes. MATERIALS AND METHODS: A retrospective study was conducted in the Department of Radiation Oncology in a tertiary cancer center between January 1, 2011, and December 31, 2015. A total of 6000 cases of cancer were analyzed, out of which cases who presented with histological proven synchronous SPM were included in this study...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485360/monotherapy-versus-combination-therapy-against-carbapenem-resistant-gram-negative-bacteria-a-retrospective-observational-study
#8
A Ghafur, V Devarajan, T Raja, J Easow, M A Raja, S Sreenivas, B Ramakrishnan, S G Raman, D Devaprasad, B Venkatachalam, R Nimmagadda
BACKGROUND: Colistin-based combination therapy (CCT) is extensively used to treat infections due to carbapenem-resistant Gram-negative bacteria (CRGNB). There are no data available from India on the usefulness of combination therapy, especially in the oncology setup. The aim of this study was to analyze the clinical effectiveness of CCT over monotherapy in patients with CRGNB. MATERIALS AND METHODS: We conducted a retrospective, observational study of patients with CRGNB bloodstream infections in our oncology and bone marrow transplant center...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485359/spectrum-of-bacteremia-in-posthematopoietic-stem-cell-transplant-patients-from-an-indian-center
#9
A Ghafur, V Devarajan, R Raj, J Easow, T Raja
BACKGROUND: Despite the relatively low prevalence of Gram-positive bacteremic infections in Indian oncology patients, glycopeptides are extensively used for empirical management of febrile neutropenia. Our aim was to analyze the spectrum of bacteremia in posthematopoietic stem cell transplant (HSCT) recipients in our center and make a recommendation on glycopeptide use in this patient population. MATERIALS AND METHODS: Retrospective analysis of bacteremic data from HSCT recipients in a tertiary care oncology and transplant center from South India, between 2011 and 2013...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485358/opium-consumption-a-potential-risk-factor-for-lung-cancer-and-pulmonary-tuberculosis
#10
A Safari, M Reazai, A Tangestaninejad, A R Mafi, Saj Mousavi
OBJECTIVE: Lung cancer is the most common malignancy, as well as the leading cause of cancer-related mortality worldwide. Several studies have shown the causative effect of cigarettes smoking in lung cancer, however, the effect of opium consumption has not yet been well studied. This study has been designed to evaluate the risk of developing lung cancer and pulmonary tuberculosis in pure opium addicts. MATERIALS AND METHODS: We designed an analytic case-control study with 490 participants...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485357/bacteriological-trends-and-antibiotic-susceptibility-patterns-of-clinical-isolates-at-government-cancer-hospital-marathwada
#11
S Nazneen, K Mukta, C Santosh, A Borde
INTRODUCTION: Preventing and starting early treatment of infections in patients whose immunity system is weak due to malignancies can reduce mortality. Since our hospital is a newly constructed one, this study aimed to determine microbial and antibiotic resistance patterns in clinical samples of patients with cancer at our center to start early treatment before the results of clinical tests are known. SUBJECTS AND METHODS: The study was carried out in the Department of Microbiology, Government Cancer Hospital during the period from January 2016 to December 2016...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485356/patterns-of-care-and-outcomes-for-second-line-targeted-therapy-in-metastatic-renal-cell-carcinomas-a-registry-based-analysis
#12
S Zanwar, A Joshi, V Noronha, V M Patil, N Sable, P Popat, S Menon, R Kothari, P Bhargava, A Kapoor, K Prabhash
AIM: Patterns of care for metastatic renal cell carcinomas (mRCC) have seen tremendous reform in the last decade. Here, we present our pattern of care in second-line targeted therapy for mRCC. METHODS: Patients with mRCC treated with second-line therapy were included from a prospective database. Demographics, risk stratification, and treatment details were noted. Event-free survival (EFS) and overall survival (OS) was calculated using Kaplan-Meier method. Log-rank test was used to identify factors affecting EFS and OS...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485355/initial-experience-with-first-line-pazopanib-in-the-treatment-of-metastatic-renal-cell-carcinoma-a-single-institution-data
#13
A Joshi, V Agarwala, A Ramaswamy, V Noronha, V M Patil, S Menon, P Popat, N Sable, K Prabhash
INTRODUCTION: Pazopanib is one of the recently introduced first-line therapeutic options in the treatment of metastatic renal cell carcinoma (mRCC). There is no published literature from India on the use of pazopanib in mRCC. MATERIALS AND METHODS: We report the efficacy and toxicity analysis of first-line pazopanib therapy administered for patients with mRCC at our institute. It is a retrospective analysis of a prospectively maintained continuous data. RESULTS: Between March 2013 and December 2015, 28 patients have been treated with pazopanib...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485354/detailed-study-of-survival-of-patients-with-renal-cell-carcinoma-in-india
#14
G P Abraham, T Cherian, P Mahadevan, T S Avinash, D George, E Manuel
PURPOSE: Renal cell carcinoma (RCC) accounts for approximately 90% of all renal malignancies. The rates of kidney cancers are high in developed countries and low in eastern countries and Africa. The objective was to conduct a survival study among Indian population following nephrectomy for RCC as there was a paucity of Indian studies in medical literature. MATERIALS AND METHODS: We conducted a follow-up study of eighty RCC patients who had nephrectomy between January 2003 and December 2010...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485353/occurrence-of-carcinoma-prostate-in-the-pune-metropolitan-region-a-5-year-study-from-2007-to-2011
#15
S S Bapat, B D Kashyapi
BACKGROUND: A retrospective study was carried out to know only the occurrence of carcinoma prostate (CAP) in the Pune Metropolitan Region (PMR) over a period of five years (January 01, 2007 to December 31, 2011). All the histopathological (HPE) reports of all prostate specimens were collected from 23 medical colleges, private institutions and stand-.alone HPE laboratories in PMR. MATERIALS AND METHODS: Four types of prostate specimens were examined - endoscopic resection, open prostatectomy, transrectal needle biopsy of prostate and prostate from the cystoprostatectomy specimen (surgery carried out for primary carcinoma bladder)...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485352/an-institutional-analysis-of-clinicopathological-features-of-triple-negative-breast-cancer
#16
D Sharma, G Singh
AIM: Most common breast cancer in India among female is breast cancer. This is heterogeneous disease, one of the subtypes, triple negative breast cancer (TNBC) defined as no expression of estrogen, progesterone receptor and neither expression nor amplification of human epidermal growth factor receptor 2/neu. TNBC is more frequent and aggressive in younger age group. The aim of this study was to evaluate clinicopathological features and outcome in TNBC versus non-TNBC group of patients...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485351/pediatric-brain-tumors-an-analysis-of-5-years-of-data-from-a-tertiary-cancer-care-center-india
#17
R Madhavan, B P Kannabiran, A M Nithya, J Kani, P Balasubramaniam, S Shanmugakumar
BACKGROUND: Pediatric brain tumors are the most common solid tumors in children and a leading cause of mortality and morbidity in children worldwide. Even though there are enough data about the epidemiology of pediatric brain tumors in western population, there are only a few reports from developing countries like India. AIMS: To study the epidemiological patterns of brain tumors in children, to study the patterns of care, and to assess the treatment response. MATERIALS AND METHODS: A retrospective epidemiological approach is used...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485350/a-case-series-of-salvage-ccnu-in-high-grade-glioma-who-have-previously-received-temozolomide-from-a-tertiary-care-institute-in-mumbai
#18
V M Patil, R Abhinav, R Tonse, S Epari, T Gupta, R Jalali
INTRODUCTION: In our center, we routinely use CCNU (Lomustine) as salvage treatment in high-grade glioma patients who cannot afford bevacizumab. This exploratory analysis was done to report the efficacy and toxicity associated with this regimen. METHODS: Patients who were treated with salvage CCNU (postexposure to temozolomide) between January 2015 and August 2016 were included for this retrospective analysis. SPSS version 16 was used for this analysis. Time-to-event analysis was performed using the Kaplan-Meier method...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485349/analysis-of-wedge-resection-of-gallbladder-bed-and-lymphadenectomy-on-adequate-oncologic-clearance-for-gallbladder-cancer
#19
M Tewari, S Kumar, S Shukla, H S Shukla
BACKGROUND: Surgery (R0 resection) is the mainstay of treatment of gallbladder cancer (GBC) as GBC is relatively resistant to currently known chemotherapy and radiotherapy regimens. AIM: to assess if wedge resection of the gallbladder bed achieves an adequate oncological clearance in GBC (namely T1 and T2) and some T3 GBC with minimal liver infiltration. PATIENTS AND METHODS: Patients with GBC who underwent radical cholecystectomy (en bloc cholecystectomy, wedge resection of the gallbladder fossa with a ≥2 cm rim of nonneoplastic liver tissue, and regional lymph node dissection) between October 2012 and June 2015 after obtaining informed consent...
October 2016: Indian Journal of Cancer
https://www.readbyqxmd.com/read/28485348/the-role-of-cox-2-and-ki-67-over-expression-in-the-prediction-of-pathologic-response-of-rectal-cancer-to-neoadjuvant-chemoradiation-therapy
#20
A H Jafarian, A Taghizadeh Kermani, J Esmaeili, N M Roshan, M Seilanian-Toosi, A A Omidi, M Karimi Shahri
BACKGROUND: The response to neoadjuvant chemoradiotherapy (CRT) is not the same among all cases with advanced rectal cancer. AIMS: This study investigated the association between over-expression of the two molecular markers (Cyclooxygenase-2 [COX-2] and Ki-67) and tumor response to neoadjuvant therapy. MATERIALS AND METHODS: In a retrospective cohort study, 55 patients with stage II-III rectal carcinoma were enrolled. All patients were treated with neoadjuvant therapy (45-50...
October 2016: Indian Journal of Cancer
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