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Drug and Therapeutics Bulletin

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https://www.readbyqxmd.com/read/28465369/statins-time-to-rationalise-lfts
#1
(no author information available yet)
Statins: time to rationalise LFTs? ● Limited evidence for low-cost devices to improve adherence ● MHRA safety alert: hyoscine butylbromide (Buscopan) injection ● Faecal microbiota transplantation for ulcerative colitis ● Magnesium for nocturnal leg cramps ● NSAIDs and risk of out-of-hospital cardiac arrest ● Off-label antidepressant prescribing.
May 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28465368/faecal-microbiota-transplantation-for-ulcerative-colitis
#2
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28465367/limited-evidence-for-low-cost-devices-to-improve-adherence
#3
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28465366/magnesium-for-nocturnal-leg-cramps
#4
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28465365/off-label-antidepressant-prescribing
#5
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28465364/mhra-safety-alert-hyoscine-butylbromide-buscopan-injection
#6
(no author information available yet)
No abstract text is available yet for this article.
May 2, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28385732/prevention-of-type-2-diabetes-where-do-you-draw-the-line
#7
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
April 6, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28373204/dtb-select-4-april-2017
#8
(no author information available yet)
Renal function monitoring of ACE inhibitors/AIIRAs ● Combating falsified medicines ● NHS England issues guidelines on conflicts of interest ● C difficile control interventions and fluoroquinolone prescribing ● NHS Scotland booklet for young people with autism ● Accuracy of asthma diagnosis in adults ● Continuity of care and reduced hospital admissions ● Screen and treat approaches for diabetes prevention.
April 3, 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28495834/testosterone-therapy-for-menopausal-women
#9
(no author information available yet)
It has been suggested that there is a link between low circulating concentrations of testosterone and reduced sexual functioning in postmenopausal women,(1) and it has been more than 60 years since the effects of testosterone therapy for the management of menopausal symptoms were first reported.(2) Since then, testosterone supplementation has received growing attention for its potential role in maintaining sexual function in menopausal women. The National Institute for Health and Care Excellence guideline on the diagnosis and management of menopause recommends considering testosterone supplementation for women with low sexual desire if hormone replacement therapy (HRT) alone has been ineffective...
May 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28495833/dequalinium-for-bacterial-vaginosis
#10
(no author information available yet)
Bacterial vaginosis is an infection characterised by overgrowth of anaerobic bacteria in the vagina with an accompanying loss of lactobacilli, and is thought to be the most common cause of abnormal vaginal discharge in women of child-bearing age.(1) Standard treatment for symptomatic bacterial vaginosis consists of a short course of an oral or topical antibiotic.(2) Dequalinium, a topical antiseptic agent, has been available for many years as a treatment for oral infections.(3) A new formulation, dequalinium 10mg vaginal tablets (Fluomizin-Kora Healthcare), was licensed in the UK in June 2015 for the treatment of bacterial vaginosis...
May 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28473353/rational-rationing
#11
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28465363/nsaids-and-risk-of-out-of-hospital-cardiac-arrest
#12
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28408390/lidocaine-prilocaine-spray-for-premature-ejaculation
#13
(no author information available yet)
Although premature ejaculation is the most common ejaculation problem, it is poorly understood and currently has no standard definition.(1) Typically, it involves reduced time to ejaculation, inability to control or delay ejaculation and associated distress.(1-5) Treatments that have been assessed include psychosexual counselling, antidepressants (e.g. selective serotonin reuptake inhibitors), phosphodiesterase type-5 inhibitors, tramadol and topical anaesthetic agents (e.g. lidocaine/prilocaine cream). A new formulation (cutaneous spray) of lidocaine/prilocaine (Fortacin-Plethora Solutions Ltd...
April 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28408389/bazedoxifene-for-hrt
#14
(no author information available yet)
Duavive (Pfizer) is a modified-release formulation of conjugated oestrogens plus bazedoxifene acetate (a selective oestrogen receptor modulator). It is licensed for treatment of oestrogen deficiency symptoms in postmenopausal women with a uterus for whom treatment with progestogen-containing therapy is not appropriate.(1,2) It was licensed by the European Medicines Agency (EMA) in 2014 and launched in the UK in July 2016.(1,3) Here, we review the evidence on efficacy and safety of conjugated oestrogens/bazedoxifene and consider its place in the management of symptoms associated with the menopause...
April 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28279979/penicillin-allergy-getting-the-label-right
#15
(no author information available yet)
Penicillin(i) allergy is a potentially serious adverse reaction that impacts on antibacterial treatment options. Although it is commonly reported and recorded in medical records, only a minority of patients with a label of penicillin allergy actually have the condition confirmed. The term 'allergy' may be incorrectly applied to adverse reactions that do not have an immunological basis and inappropriate labelling of penicillin allergy can lead to the unnecessary avoidance of penicillins and other beta-lactam antibacterials...
March 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28279978/desmopressin-for-nocturia-in-adults
#16
(no author information available yet)
Desmopressin has been used for many years in the treatment of diabetes insipidus, nocturnal enuresis (involuntary urination while asleep) and nocturia associated with multiple sclerosis (in adults aged up to 65 years); it has also been recommended in certain circumstances for the treatment of nocturia in men and women (previously, an unlicensed use).(1,2) Recently, a new brand of desmopressin sublingual tablet (lyophilisate-an orally disintegrating tablet; Noqdirna-Ferring) has been licensed for use in adults of any age for the treatment of nocturia due to idiopathic nocturnal polyuria...
March 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28254997/better-preparation-needed
#17
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28242628/dtb-select-3-march-2017
#18
(no author information available yet)
Potential for abuse and misuse of pregabalin and gabapentin | Risk of depression and suicidal thoughts with ▼apremilast | Are patients overly optimistic about outcomes? | Pioglitazone and cardiovascular outcomes | Antipsychotics and risk of acute respiratory failure in patients with COPD | Improving adherence to lipid-lowering drugs | ▼Canagliflozin associated with increased risk of amputation | Medical research news stories: how independent and qualified are commenters?
March 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28183724/understanding-qualitative-research-in-health-care
#19
(no author information available yet)
Qualitative studies are often used to research phenomena that are difficult to quantify numerically.(1,2) These may include concepts, feelings, opinions, interpretations and meanings, or why people behave in a certain way. Although qualitative research is often described in opposition to quantitative research, the approaches are complementary, and many researchers use mixed methods in their projects, combining the strengths of both approaches.(2) Many comprehensive texts exist on qualitative research methodology including those with a focus on healthcare related research...
February 2017: Drug and Therapeutics Bulletin
https://www.readbyqxmd.com/read/28183723/%C3%A2-daclizumab-for-ms
#20
(no author information available yet)
▼Daclizumab (Zinbryta-Biogen Idec) is a new injectable disease-modifying drug licensed for the treatment of relapsing forms of multiple sclerosis (MS) in adults.(1) It is a humanised monoclonal antibody that modulates interleukin-2 signalling.(1-3) Here, we review the evidence on daclizumab and consider its place in the management of MS.
February 2017: Drug and Therapeutics Bulletin
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