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Caries Research

Angelo Giuseppe Roncalli, Aubrey Sheiham, Georgios Tsakos, Georgia Costa de Araújo-Souza, Richard G Watt
Dental caries levels have declined in children since the 1970s in many countries. Most of the postulated main reasons for the decline are speculative and have not been rigorously evaluated. The objective of this study was to assess the relationship between some social factors and the decline in dental caries in Brazilian 12-year-old children from 1996 to 2010. Secondary analysis of national data was performed in 27 Brazilian state capitals. A panel data regression model with fixed effects and multiple linear regression were used to verify the relationship between the explanatory and the dependent variables and also the time-trend effect...
October 6, 2016: Caries Research
Peter Wetselaar, Jan H Vermaire, Corine M Visscher, Frank Lobbezoo, Annemarie A Schuller
This study aimed to assess the prevalence of tooth wear in different age groups of the Dutch adult population and to determine this tooth wear distribution by gender, socioeconomic class, and type of teeth. Results were compared with the outcomes of a previous study in a comparable population. As part of a comprehensive investigation of the oral health of the general Dutch adult population in 2013, tooth wear was assessed among 1,125 subjects in the city of 's-Hertogenbosch. The data collected were subjected to stratified analysis by 5 age groups (25-34, 35-44, 45-54, 55-64, and 65-74 years), gender, socioeconomic class, and type of teeth...
October 1, 2016: Caries Research
Joana Christina Carvalho, Irene Dige, Vita Machiulskiene, Vibeke Qvist, Azam Bakhshandeh, Clarissa Fatturi-Parolo, Marisa Maltz
The management of occlusal caries still remains a major challenge for researchers as well as for general practitioners. The present paper reviews and discusses the most up-to-date knowledge and evidence of the biological principles guiding diagnosis, risk assessment, and management of the caries process on occlusal surfaces. In addition, it considers the whole spectrum of the caries process on occlusal surfaces, ranging from the molecular ecology of occlusal biofilms to the management of deep occlusal caries lesions...
September 23, 2016: Caries Research
Hedwig Hofstetter, Elise Dusseldorp, Achim Zeileis, Annemarie A Schuller
In dental epidemiology, the decayed (D), missing (M), and filled (F) teeth or surfaces index (DFM index) is a frequently used measure. The DMF index is characterized by a strongly positive skewed distribution with a large stack of zero counts for those individuals without caries experience. Therefore, standard generalized linear models often lead to a poor fit. The hurdle regression model is a highly suitable class to model a DMF index, but its use is subordinated. We aim to overcome the gap between the suitability of the hurdle model to fit DMF indices and the frequency of its use in caries research...
September 17, 2016: Caries Research
Viivi Alaraudanjoki, Marja-Liisa Laitala, Leo Tjäderhane, Paula Pesonen, Adrian Lussi, Jukka Ronkainen, Vuokko Anttonen
OBJECTIVE: To assess the influence of self-reported intrinsic factors [gastroesophageal reflux disease (GERD), long-term alcoholism, long-term heavy use of alcohol and multiple pregnancies] on erosive tooth wear in a middle-aged cohort sample. MATERIALS AND METHODS: Of the total Northern Finland Birth Cohort (NFBC 1966), a convenience sample (n = 3,181) was invited for an oral health examination in 2012-2013, of which 1,962 participated, comprising the final study group...
2016: Caries Research
Areerat Nirunsittirat, Waranuch Pitiphat, Christy M McKinney, Timothy A DeRouen, Nusara Chansamak, Onauma Angwaravong, Piyachat Patcharanuchat, Taksin Pimpak
This cohort study was conducted in Khon Kaen, Thailand, to test the hypothesis that a longer breastfeeding duration increases the risk for dental caries in primary teeth. We collected information on infant feeding practices and potential confounders using a structured questionnaire to interview mothers or caregivers during the second trimester of pregnancy and after birth at 21 days and at 3, 12, 18, 24, and 36 months. Regardless of other liquids and foods, full breastfeeding was defined as feeding breast milk but not formula, while any breastfeeding was feeding breast milk with or without formula...
2016: Caries Research
Karsten Henne, Antonia-Patricia Gunesch, Carolin Walther, Hendrik Meyer-Lueckel, Georg Conrads, Marcella Esteves-Oliveira
Dental caries is a multifactorial disease with many associated microbial taxa, but only a few are notably contributing to acidogenicity. The ribosome number and the corresponding 16S ribosomal RNA (rRNA) concentration are considered a molecular indicator for general metabolic activity of bacteria, as they are elevated with increased anabolic and catabolic activities. We hypothesize that the activity of aciduric/acidogenic bacterial taxa, reflected by a rise in ribosomal counts, could resolve differences between plaque biofilm from sound surfaces and caries lesions...
2016: Caries Research
Justin T van der Tas, Lea Kragt, Jaap J S Veerkamp, Vincent W V Jaddoe, Henriette A Moll, Edwin M Ongkosuwito, Marlies E C Elfrink, Eppo B Wolvius
The aim of this study was to investigate potential differences in caries prevalence of children from ethnic minority groups compared to native Dutch children and the influence of socio-economic status (SES) and parent-reported oral health behaviour on this association. The study had a cross-sectional design, embedded in a population-based prospective multi-ethnic cohort study. 4,306 children with information on caries experience, belonging to 7 different ethnic groups, participated in this study. The decayed, missing, and filled teeth (dmft) index was assessed at the age of 6 and categorized in two ways for analysis: children without caries (dmft = 0) versus any caries experience (dmft >0) and children without caries (dmft = 0) versus children with mild caries (dmft = 1-3) or severe caries (dmft >3)...
2016: Caries Research
Lea Kragt, Justin T van der Tas, Henriëtte A Moll, Marlies E C Elfrink, Vincent W V Jaddoe, Eppo B Wolvius, Edwin M Ongkosuwito
Oral health-related quality of life (OHRQOL) is the perceived impact of one's own oral health on daily life. Oral diseases influence children's OHRQOL directly, but OHRQOL might also be related to oral health experiences from the past. We investigate the relation between dental caries at the age of 6 with OHRQOL assessed at the age of 10. This study was conducted within the Generation R Study, a population-based prospective cohort study. Caries experience was assessed with the decayed, missing, and filled teeth index (dmft) at a median age of 6...
2016: Caries Research
Ana Carolina Magalhães, Milena Gargaro Dos Santos, Livia Picchi Comar, Marília Afonso Rabelo Buzalaf, Carolina Ganss, Nadine Schlueter
This study investigated the isolated and combined effect of a single application of TiF4 or NaF varnish versus daily use of a solution containing a low concentration of TiF4/NaF against tooth erosion in vitro. A total of 90 bovine enamel and 108 root dentin samples were treated as follows: control (no treatment), solution containing TiF4/NaF (500 ppm F-, pH 4.4), NaF varnish (24,500 ppm F-, pH 5.0), TiF4 varnish (24,500 ppm F-, pH 1.0), TiF4 varnish + solution, and NaF varnish + solution. The erosive challenges were performed 4 × 90s/day (0...
2016: Caries Research
Nadine Schlueter, Katja Jung, Carolina Ganss
Profilometry is established in erosion research. However, in the case of dentine, factors such as the demineralised organic matrix, desiccation effects, or type of measuring device may have an impact on the measurement results, which were investigated in the present study. Dentine specimens were eroded with citric acid (1%, pH 2.6) for 5, 10, 15, 20, 30, 60, 90, and 120 min (n = 15 each). For each specimen, tissue loss was determined under various conditions - before/after enzymatic matrix removal, under standardised wet and desiccated (2/10 min) conditions - with non-contact and contact profilometry...
2016: Caries Research
M C Priesnitz, R K Celeste, M J Pereira, C A Pires, C A Feldens, P F Kramer
OBJECTIVES: To investigate the association between neighbourhood factors and decayed, missing, and filled teeth (dmft) index among preschool children. METHODS: The sample of this cross-sectional study comprised 1,110 children (0-5 years old) clustered in 16 official neighbourhoods of Canoas city, southern Brazil. Multilevel binomial models were used to estimate the association of contextual variables at neighbourhood level (Human Development Index, average income, and public primary health care units) with two oral health outcomes: decayed teeth (dt) and missing or filled teeth (mft), after adjusting for individual variables (gender, age, maternal education, equivalent household income logarithm, household, and point of care)...
2016: Caries Research
Mahtab Memarpour, Shorangize Dadaein, Ebrahim Fakhraei, Mehrdad Vossoughi
Early childhood caries, a serious health problem among young children, can be prevented with effective intervention. The aim of this study was to evaluate the efficacy of oral health education and a fluoride varnish in the prevention of caries in children under the age of 3 years. For this single-blind randomized parallel group 1-year clinical trial in Shiraz, 300 children aged 12-24 months with sound primary teeth were selected and randomly divided into three groups (n = 100): (1) control: no preventive intervention; (2) oral health counseling, and (3) oral health counseling and fluoride varnish at baseline and 6 months later...
2016: Caries Research
Nobuhiro Takahashi, Bente Nyvad
Recent advances regarding the caries process indicate that ecological phenomena induced by bacterial acid production tilt the de- and remineralization balance of the dental hard tissues towards demineralization through bacterial acid-induced adaptation and selection within the microbiota - from the dynamic stability stage to the aciduric stage via the acidogenic stage [Takahashi and Nyvad, 2008]. Dentin and root caries can also be partly explained by this hypothesis; however, the fact that these tissues contain a considerable amount of organic material suggests that protein degradation is involved in caries formation...
2016: Caries Research
Lina María Marín, Jaime Aparecido Cury, Livia Maria Andaló Tenuta, Jaime Eduardo Castellanos, Stefania Martignon
Fluorotic teeth could either be more resistant or more susceptible to the caries process than sound ones due to their higher enamel fluoride concentration and higher porosity (subsurface hypomineralization), respectively; however, there is no consensus on this subject. In this study, a total of 49 human unerupted third molars presenting Thylstrup and Fejerskov (TF) fluorosis scores 0-4 were used. Two enamel slabs were obtained from each tooth. The rest of the tooth crown was powdered, and the enamel was separated from the dentine...
2016: Caries Research
Carlos Alberto Feldens, Thiago Machado Ardenghi, Angela Isabel Dos Santos Dullius, Fabiana Vargas-Ferreira, Pedro Antonio González Hernandez, Paulo Floriani Kramer
The aim of the present study was to investigate the effect of dental caries experience and the components of the decayed, missing and filled teeth (DMFT) index on oral health-related quality of life (OHRQoL) among adolescents in southern Brazil. A cross-sectional study was conducted with 509 adolescents aged 11-14 years enrolled at public schools in the municipality of Osório (southern Brazil). A calibrated examiner performed the clinical examination for caries (World Health Organization: DMFT index), malocclusion (Dental Aesthetic Index) and traumatic dental injuries [Andreasen et al...
2016: Caries Research
Amnah Algarni, Hobin Kang, Daniel Fried, George J Eckert, Anderson T Hara
Optical coherence tomography (OCT) has been introduced in dentistry as a nondestructive diagnostic imaging tool that does not utilize ionizing radiation. This study investigated the agreement between polarization-sensitive OCT (PS-OCT), microcomputed tomography (μ-CT), and histology for enamel thickness measurements. Human enamel samples were prepared and evaluated with μ-CT and PS-OCT and then sectioned and observed via digital transversal light microscopy. For all methods, a standard transversal section (b-scan) in each sample was selected, and the enamel thickness was measured at three predetermined positions using ImageJ analysis software...
2016: Caries Research
Esber Caglar, Mehmet Görgülü, Ozgur O Kuscu
Dental caries and wear are important conditions to record in archaeological collections. The aim of the present paper is to determine the frequency and distribution of dental caries and dental wear in a mediaeval Byzantine paediatric population in Yenikapı, Constantinople, Istanbul. The present research was carried out on the skeletal remains of 1 infant and 28 children with a total of 180 teeth (113 primary and 67 permanent teeth). The frequency of ante-mortem tooth loss in the sample was 1%. The total frequency of carious lesions in the sample was 2...
2016: Caries Research
Álfheiður Ástvaldsdóttir, Aron Naimi-Akbar, Thomas Davidson, Agneta Brolund, Laura Lintamo, Anna Attergren Granath, Sofia Tranæus, Pernilla Östlund
OBJECTIVES: To evaluate the available evidence that the use of arginine-containing dental care products prevents the development of new caries lesions and the progression of existing lesions. SEARCH METHODS: We performed a systematic literature search of databases including PubMed, the Cochrane Library and EMBASE. SELECTION CRITERIA: We selected randomized controlled trials of treatment with arginine in fluoride-containing dental products measuring dental caries incidence or progression in children, adults and elderly subjects...
2016: Caries Research
Frank Lippert
Two mechanistic, laboratory, factorial design studies were conducted to investigate the effect of the stannous ion (Sn2+) in the absence or presence of fluoride on caries lesion de- and remineralization. Study I was concerned with determining changes in mineral distribution of subsurface lesions, whereas study II investigated changes in surface hardness of surface-softened lesions as a function of pH. Study I showed that Sn2+ modulates the effects of fluoride by preventing lamination. Study II revealed that the effect of Sn2+ on rehardening is pH dependent...
2016: Caries Research
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