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Caries Research

Zsuzsanna Tóth
No abstract text is available yet for this article.
December 2, 2016: Caries Research
Gabriela Dos Santos Pinto, Luciana de Ávila Quevedo, Marcos Britto Correa, Marina Sousa Azevedo, Marília Leão Goettems, Ricardo Tavares Pinheiro, Flávio Fernando Demarco
AIM: To investigate the relationship between maternal depression and childhood caries in a cohort of adolescent mothers. METHODS: This cross-sectional study nested in a cohort evaluated a sample of 538 mother/child dyads. When the children were 24-36 months of age, data regarding oral health from children and mothers were collected by clinical dental examination. A mother's major depressive disorder was assessed by using the Mini International Neuropsychiatric Interview (MINI [Plus]), at the current moment...
November 30, 2016: Caries Research
Yousef M Alyousef, J Francis Borgio, Sayed AbdulAzeez, Naif Al-Masoud, Ali A Al-Ali, Emad Al-Shwaimi, Amein K Al-Ali
The high prevalence of dental caries in children worldwide is a major oral health problem which requires early intervention. Dental caries is mainly caused by the action of acids produced by bacteria in addition to many other factors. Recent genetic studies have reported that a number of genes are associated with the susceptibility to dental caries. The majority of these genes are associated with inflammation, increased susceptibility to infection, and dentine matrix formation. Using the TaqMan assay and direct DNA sequencing, the prevalence of 6 single-nucleotide polymorphisms (SNPs) in MMP9, MBL2, MMP2, and TIMP2 genes was determined in 102 children with caries and in 100 age-matched caries-free controls...
November 29, 2016: Caries Research
Lydie Izakovicova Holla, Petra Borilova Linhartova, Jakub Kastovsky, Michaela Bartosova, Kristina Musilova, Lubomir Kukla, Martina Kukletova
AIM: We analyzed the VDR TaqI (rs731236) gene polymorphism in children with and those without dental caries. METHODS: A total of 388 subjects, 153 caries-free (with decayed/missing/filled teeth [DMFT] = 0) and 235 children with dental caries (DMFT ≥1), were genotyped by the TaqMan method. RESULTS: Although no significant differences in VDR TaqI allele and genotype frequencies between caries-free and caries-affected children were detected, a significant association between this polymorphism and gingivitis was found (p < 0...
November 26, 2016: Caries Research
Chiara O Navarra, Antonietta Robino, Nicola Pirastu, Lorenzo Bevilacqua, Paolo Gasparini, Roberto Di Lenarda, Sergio Crovella
BACKGROUND: The DEFB1 gene, encoding for the constitutively expressed human β-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. METHODS: We analysed 5 DEFB1 polymorphisms, namely 3 functional single-nucleotide polymorphisms (SNPs) at the 5'-untranslated region (UTR), -52G>A (rs1799946), -44C>G (rs1800972), and -20G>A (rs11362), 2 SNPs at the 3'-UTR, c*5G>A (rs1047031) and c*87A>G (rs1800971) SNP located in potential miRNA binding sites, looking for possible correlations with the risk to develop caries in 654 adult subjects from isolated populations of north-eastern Italy...
November 16, 2016: Caries Research
Alaa A Alkhateeb, Lloyd A Mancl, Richard B Presland, Marilynn L Rothen, Donald L Chi
Salivary flow rate, pH, and buffering capacity are associated with dental caries, but studies from the cystic fibrosis (CF) literature are inconclusive regarding these salivary factors and caries. The aim of this study was to evaluate these factors and their associations with dental caries in individuals with CF. Unstimulated whole saliva was collected from individuals aged 6-20 years at Seattle Children's Hospital CF Clinic, USA (n = 83). Salivary flow rate was measured in milliliters per minute. Salivary pH was assessed using a laboratory pH meter...
November 16, 2016: Caries Research
Eliana M Takeshita, Marcelle Danelon, Luciene P Castro, Robson F Cunha, Alberto C B Delbem
OBJECTIVE: To evaluate the effect of a low-fluoride (F) toothpaste supplemented with sodium trimetaphosphate (TMP) on enamel remineralization in situ. DESIGN: Bovine enamel blocks were selected on the basis of their surface hardness (SH) after caries-like lesions had been induced, and randomly divided into 4 treatment groups, according to the toothpastes used: without F or TMP (placebo); 500 ppm F; 500 ppm F plus 1% TMP; and 1,100 ppm F. The study design was blinded and crossover and performed in 4 phases of 3 days each...
November 4, 2016: Caries Research
Gwen Falony, Sisko Honkala, Riina Runnel, Jana Olak, Rita Nõmmela, Silvia Russak, Mare Saag, Pirkko-Liisa Mäkinen, Kauko Mäkinen, Tero Vahlberg, Eino Honkala
OBJECTIVE: To assess the effect of daily consumption of erythritol, xylitol, and sorbitol candies on caries development in mixed dentition during a 3-year intervention and 3 years after the intervention. METHODS: 485 Estonian first- and second-grade primary school children participated. Children were randomly allocated to an erythritol, xylitol, or sorbitol (control) group. Polyol-containing candies were administered on school days with a daily polyol consumption of 3 × 2...
November 3, 2016: Caries Research
Cristina Palacios, Sona Rivas-Tumanyan, Evangelia Morou-Bermúdez, Alina M Colon, Roxana Y Torres, Augusto R Elías-Boneta
OBJECTIVE: To identify the types, food sources, and pattern of carbohydrates that significantly contribute to dental caries in Puerto Rican children. METHODS: As part of an island-wide cross-sectional oral health study in 1,587 twelve-year-olds, diet intake was assessed in a representative subset (n = 801) with a 24-hour dietary recall. Carbohydrate intake was quantified using a computer-based diet analysis program. Caries was assessed using the National Institute of Dental and Craniofacial Research diagnostic criteria...
October 28, 2016: Caries Research
Angelo Giuseppe Roncalli, Aubrey Sheiham, Georgios Tsakos, Georgia Costa de Araújo-Souza, Richard G Watt
Dental caries levels have declined in children since the 1970s in many countries. Most of the postulated main reasons for the decline are speculative and have not been rigorously evaluated. The objective of this study was to assess the relationship between some social factors and the decline in dental caries in Brazilian 12-year-old children from 1996 to 2010. Secondary analysis of national data was performed in 27 Brazilian state capitals. A panel data regression model with fixed effects and multiple linear regression were used to verify the relationship between the explanatory and the dependent variables and also the time-trend effect...
October 6, 2016: Caries Research
Peter Wetselaar, Jan H Vermaire, Corine M Visscher, Frank Lobbezoo, Annemarie A Schuller
This study aimed to assess the prevalence of tooth wear in different age groups of the Dutch adult population and to determine this tooth wear distribution by gender, socioeconomic class, and type of teeth. Results were compared with the outcomes of a previous study in a comparable population. As part of a comprehensive investigation of the oral health of the general Dutch adult population in 2013, tooth wear was assessed among 1,125 subjects in the city of 's-Hertogenbosch. The data collected were subjected to stratified analysis by 5 age groups (25-34, 35-44, 45-54, 55-64, and 65-74 years), gender, socioeconomic class, and type of teeth...
October 1, 2016: Caries Research
Joana Christina Carvalho, Irene Dige, Vita Machiulskiene, Vibeke Qvist, Azam Bakhshandeh, Clarissa Fatturi-Parolo, Marisa Maltz
The management of occlusal caries still remains a major challenge for researchers as well as for general practitioners. The present paper reviews and discusses the most up-to-date knowledge and evidence of the biological principles guiding diagnosis, risk assessment, and management of the caries process on occlusal surfaces. In addition, it considers the whole spectrum of the caries process on occlusal surfaces, ranging from the molecular ecology of occlusal biofilms to the management of deep occlusal caries lesions...
September 23, 2016: Caries Research
Hedwig Hofstetter, Elise Dusseldorp, Achim Zeileis, Annemarie A Schuller
In dental epidemiology, the decayed (D), missing (M), and filled (F) teeth or surfaces index (DFM index) is a frequently used measure. The DMF index is characterized by a strongly positive skewed distribution with a large stack of zero counts for those individuals without caries experience. Therefore, standard generalized linear models often lead to a poor fit. The hurdle regression model is a highly suitable class to model a DMF index, but its use is subordinated. We aim to overcome the gap between the suitability of the hurdle model to fit DMF indices and the frequency of its use in caries research...
September 17, 2016: Caries Research
Viivi Alaraudanjoki, Marja-Liisa Laitala, Leo Tjäderhane, Paula Pesonen, Adrian Lussi, Jukka Ronkainen, Vuokko Anttonen
OBJECTIVE: To assess the influence of self-reported intrinsic factors [gastroesophageal reflux disease (GERD), long-term alcoholism, long-term heavy use of alcohol and multiple pregnancies] on erosive tooth wear in a middle-aged cohort sample. MATERIALS AND METHODS: Of the total Northern Finland Birth Cohort (NFBC 1966), a convenience sample (n = 3,181) was invited for an oral health examination in 2012-2013, of which 1,962 participated, comprising the final study group...
2016: Caries Research
Areerat Nirunsittirat, Waranuch Pitiphat, Christy M McKinney, Timothy A DeRouen, Nusara Chansamak, Onauma Angwaravong, Piyachat Patcharanuchat, Taksin Pimpak
This cohort study was conducted in Khon Kaen, Thailand, to test the hypothesis that a longer breastfeeding duration increases the risk for dental caries in primary teeth. We collected information on infant feeding practices and potential confounders using a structured questionnaire to interview mothers or caregivers during the second trimester of pregnancy and after birth at 21 days and at 3, 12, 18, 24, and 36 months. Regardless of other liquids and foods, full breastfeeding was defined as feeding breast milk but not formula, while any breastfeeding was feeding breast milk with or without formula...
2016: Caries Research
Karsten Henne, Antonia-Patricia Gunesch, Carolin Walther, Hendrik Meyer-Lueckel, Georg Conrads, Marcella Esteves-Oliveira
Dental caries is a multifactorial disease with many associated microbial taxa, but only a few are notably contributing to acidogenicity. The ribosome number and the corresponding 16S ribosomal RNA (rRNA) concentration are considered a molecular indicator for general metabolic activity of bacteria, as they are elevated with increased anabolic and catabolic activities. We hypothesize that the activity of aciduric/acidogenic bacterial taxa, reflected by a rise in ribosomal counts, could resolve differences between plaque biofilm from sound surfaces and caries lesions...
2016: Caries Research
Justin T van der Tas, Lea Kragt, Jaap J S Veerkamp, Vincent W V Jaddoe, Henriette A Moll, Edwin M Ongkosuwito, Marlies E C Elfrink, Eppo B Wolvius
The aim of this study was to investigate potential differences in caries prevalence of children from ethnic minority groups compared to native Dutch children and the influence of socio-economic status (SES) and parent-reported oral health behaviour on this association. The study had a cross-sectional design, embedded in a population-based prospective multi-ethnic cohort study. 4,306 children with information on caries experience, belonging to 7 different ethnic groups, participated in this study. The decayed, missing, and filled teeth (dmft) index was assessed at the age of 6 and categorized in two ways for analysis: children without caries (dmft = 0) versus any caries experience (dmft >0) and children without caries (dmft = 0) versus children with mild caries (dmft = 1-3) or severe caries (dmft >3)...
2016: Caries Research
Lea Kragt, Justin T van der Tas, Henriëtte A Moll, Marlies E C Elfrink, Vincent W V Jaddoe, Eppo B Wolvius, Edwin M Ongkosuwito
Oral health-related quality of life (OHRQOL) is the perceived impact of one's own oral health on daily life. Oral diseases influence children's OHRQOL directly, but OHRQOL might also be related to oral health experiences from the past. We investigate the relation between dental caries at the age of 6 with OHRQOL assessed at the age of 10. This study was conducted within the Generation R Study, a population-based prospective cohort study. Caries experience was assessed with the decayed, missing, and filled teeth index (dmft) at a median age of 6...
2016: Caries Research
Ana Carolina Magalhães, Milena Gargaro Dos Santos, Livia Picchi Comar, Marília Afonso Rabelo Buzalaf, Carolina Ganss, Nadine Schlueter
This study investigated the isolated and combined effect of a single application of TiF4 or NaF varnish versus daily use of a solution containing a low concentration of TiF4/NaF against tooth erosion in vitro. A total of 90 bovine enamel and 108 root dentin samples were treated as follows: control (no treatment), solution containing TiF4/NaF (500 ppm F-, pH 4.4), NaF varnish (24,500 ppm F-, pH 5.0), TiF4 varnish (24,500 ppm F-, pH 1.0), TiF4 varnish + solution, and NaF varnish + solution. The erosive challenges were performed 4 × 90s/day (0...
2016: Caries Research
Nadine Schlueter, Katja Jung, Carolina Ganss
Profilometry is established in erosion research. However, in the case of dentine, factors such as the demineralised organic matrix, desiccation effects, or type of measuring device may have an impact on the measurement results, which were investigated in the present study. Dentine specimens were eroded with citric acid (1%, pH 2.6) for 5, 10, 15, 20, 30, 60, 90, and 120 min (n = 15 each). For each specimen, tissue loss was determined under various conditions - before/after enzymatic matrix removal, under standardised wet and desiccated (2/10 min) conditions - with non-contact and contact profilometry...
2016: Caries Research
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