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Caries Research

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https://www.readbyqxmd.com/read/28772269/effects-of-self-assembling-peptide-p11-4-fluorides-and-caries-infiltration-on-artificial-enamel-caries-lesions-in-vitro
#1
Richard J Wierichs, Julian Kogel, Julian Lausch, Marcella Esteves-Oliveira, Hendrik Meyer-Lueckel
The application of a self-assembling peptide on noncavitated caries lesions is supposed to be a feasible approach to facilitate remineralization and mask their unfavorable appearance. However, demineralizing conditions are common in the oral environment, so the aim of this pH-cycling study was to compare recommended and novel treatment methods regarding their ability to hamper demineralization and as a consequence mask artificial enamel caries lesions. Artificial caries lesions were prepared in bovine enamel and randomly allocated to 11 groups (n = 22)...
August 4, 2017: Caries Research
https://www.readbyqxmd.com/read/28738384/sweet-taste-perception-and-dental-caries-in-13-to-15-year-olds-a-multicenter-cross-sectional-study
#2
H Ashi, C Lara-Capi, G Campus, G Klingberg, P Lingström
Dietary habits and, in particular, the intake frequency of sucrose are of major importance for the development of dental caries. The perception of sweet taste is believed to have an influence on sucrose intake and therefore affects the predisposition to dental caries. The aim was to study the caries experience and sweet taste perception and to further analyze the possible relationship between the 2 tested variables in 13- to 15-year-old children from 3 different geographical areas. A cross-sectional survey comprising 669 children (220 Italian, 224 Mexican, and 225 Saudi Arabian) was conducted...
July 25, 2017: Caries Research
https://www.readbyqxmd.com/read/28728145/extracellular-dna-contributes-to-dental-biofilm-stability
#3
Sebastian Schlafer, Rikke L Meyer, Irene Dige, Viduthalai R Regina
Extracellular DNA (eDNA) is a major matrix component of many bacterial biofilms. While the presence of eDNA and its role in biofilm stability have been demonstrated for several laboratory biofilms of oral bacteria, there is no data available on the presence and function of eDNA in in vivo grown dental biofilms. This study aimed to determine whether eDNA was part of the matrix in biofilms grown in situ in the absence of sucrose and whether treatment with DNase dispersed biofilms grown for 2.5, 5, 7.5, 16.5, or 24 h...
July 21, 2017: Caries Research
https://www.readbyqxmd.com/read/28668961/single-nucleotide-polymorphism-in-the-aetiology-of-caries-systematic-literature-review
#4
Paula Piekoszewska-Ziętek, Anna Turska-Szybka, Dorota Olczak-Kowalczyk
Recent progress in the field of molecular biology and techniques of DNA sequence analysis allowed determining the meaning of hereditary factors of many common human diseases. Studies of genetic mechanisms in the aetiology of caries encompass, primarily, 4 main groups of genes responsible for (1) the development of enamel, (2) formation and composition of saliva, (3) immunological responses, and (4) carbohydrate metabolism. The aim of this study was to present current knowledge about the influence of single nucleotide polymorphism (SNP) genetic variants on the occurrence of dental caries...
July 1, 2017: Caries Research
https://www.readbyqxmd.com/read/28658675/caries-experience-in-children-with-and-without-molar-incisor-hypomineralisation-a-case-control-study
#5
Juliana de Aguiar Grossi, Renata Nunes Cabral, Soraya Coelho Leal
AIM: The aim of this study was to compare the caries experience of children with and without molar-incisor hypomineralisation (MIH). METHODS: A case-control study was designed in which 130 children aged between 7 and 13 years with MIH (cases) were matched with 130 children without the condition (controls) according to age, sex, and school. Dental caries and MIH were assessed using the Caries Assessment Spectrum and Treatment (CAST) and European Academy of Paediatric Dentistry (EAPD) criteria, respectively, by three examiners...
June 29, 2017: Caries Research
https://www.readbyqxmd.com/read/28641301/fluoride-in-dental-biofilm-varies-across-intra-oral-regions
#6
Line Staun Larsen, Vibeke Baelum, Livia Maria Andaló Tenuta, Alan Richards, Bente Nyvad
Information on differences in biofilm fluoride concentration across intra-oral regions may help explain the distribution of caries within the dentition. The aim of this cross-sectional study was to describe the fluoride concentration in saliva and in biofilm fluid and biofilm solids across 6 intra-oral regions. Unstimulated whole saliva was collected from 42 participants and biofilm harvested from the buccal sites in the 4 molar and 2 anterior regions. Samples were collected at least 1 h after use of fluoride dentifrice...
June 23, 2017: Caries Research
https://www.readbyqxmd.com/read/28637033/quantitative-swept-source-optical-coherence-tomography-of-early-enamel-erosion-in-vivo
#7
Rupert S Austin, Maisalamah Haji Taha, Frederic Festy, Richard Cook, Manoharan Andiappan, Juliana Gomez, Iain A Pretty, Rebecca Moazzez
Swept-source optical coherence tomography (SS-OCT) shows potential for the in vivo quantitative evaluation of micro-structural enamel surface phenomena occurring during early erosive demineralization. This randomized controlled single-blind cross-over clinical study aimed to evaluate the use of SS-OCT for detecting optical changes in the enamel of 30 healthy volunteers subjected to orange juice rinsing (erosive challenge) in comparison to mineral water rinsing (control), according to wiped and non-wiped enamel surface states...
June 22, 2017: Caries Research
https://www.readbyqxmd.com/read/28633135/children-with-a-higher-activity-of-carbonic-anhydrase-vi-in-saliva-are-more-likely-to-develop-dental-caries
#8
Daniele de Cassia Rodrigues Picco, Lenita Marangoni Lopes, Marcelo Rocha Marques, Sergio Roberto Peres Line, Thaís Manzano Parisotto, Marinês Nobre Dos Santos
OBJECTIVE: This study aimed to analyze the concentration and activity of carbonic anhydrase (CA) VI in the saliva of school children. We investigated the relationship among caries, CA VI concentration/activity, flow rate, pH, and buffering capacity. MATERIALS AND METHODS: Seventy-four school children were divided into a caries-free group and a caries group. Clinical examinations were conducted by one examiner according to World Health Organization criteria + early caries lesions...
June 21, 2017: Caries Research
https://www.readbyqxmd.com/read/28618424/preventive-and-therapeutic-proximal-sealing-a-3-5-year-randomized-controlled-clinical-trial-follow-up
#9
Cristian P Basili, Claes Göran Emilson, Gonzalo C Corvalan, Maria Paz Moran, Carlos Torres, Mariela D Quiroz, Santiago Sergio Gomez
OBJECTIVE: The aim of this split-mouth, randomized controlled clinical trial was to evaluate the efficacy of proximal sealing for avoiding the development of new caries lesions or arresting incipient caries lesions on the mesial surface of first permanent molars (6m) abutting lesions on the distal surface of second primary molars (05d) in children at high caries risk. METHODS: A total of 61 children 8-10 years old were selected based on the caries status of the proximal sites of 05d and 6m...
June 16, 2017: Caries Research
https://www.readbyqxmd.com/read/28564647/64th-orca-congress-july-5-8-2017-oslo-norway-abstracts
#10
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2017: Caries Research
https://www.readbyqxmd.com/read/28538220/identification-of-caries-risk-determinants-in-toddlers-results-of-the-gusto-birth-cohort-study
#11
C Un Lam, L W Khin, A C Kalhan, R Yee, Y S Lee, M F-F Chong, K Kwek, S M Saw, K Godfrey, Y S Chong, C-Y Hsu
The aim of this study was to identify risk determinants leading to early childhood caries (ECC) and visible plaque (VP) in toddlers. Data for mother-child pairs participating in the Growing Up in Singapore towards Healthy Outcomes (GUSTO) birth cohort were collected from pregnancy to toddlerhood. Oral examinations were performed in 543 children during their clinic visit at 24 months to detect ECC and VP. Following logistic regression, ECC and VP were jointly regressed as primary and secondary outcomes, respectively, using the bivariate probit model...
May 25, 2017: Caries Research
https://www.readbyqxmd.com/read/28535503/determining-an-upper-reference-value-for-the-urinary-fluoride-creatinine-ratio-in-healthy-children-younger-than-7-years
#12
F Vida Zohoori, A Maguire
The urinary fluoride/creatinine ratio (UF/Cr) in a spot urine sample could be a useful systemic F exposure monitoring tool. No reference value for UF/Cr currently exists, therefore this study aimed to establish an upper reference value for a UF/Cr, corresponding to excessive systemic F exposure, i.e., >0.07 mg F/kg body weight (b.w.)/day, in children. Subsidiary aims were to examine the relationship between (i) total daily F intake (TDFI) and 24-h urinary F excretion (DUFE); (ii) DUFE and UF/Cr, and (iii) TDFI and UF/Cr...
May 24, 2017: Caries Research
https://www.readbyqxmd.com/read/28521310/the-impact-of-the-demineralized-organic-matrix-on-the-effect-of-tif4-varnish-on-the-progression-of-dentin-erosive-loss
#13
Beatriz Martines de Souza, Mariele Vertuan, Marília Afonso Rabelo Buzalaf, Ana Carolina Magalhães
This in vitro study compared the effect of TiF4 varnish with that of NaF varnish, applied on pre-eroded bovine dentin samples, with respect to the progression of erosive loss, in the presence or absence of the demineralized organic matrix (DOM). One hundred and sixty bovine dentin samples were pre-eroded (0.1% citric acid, pH 2.5, 30 min). Half of the samples were subjected to the DOM removal (collagenase solution, 5 days). Samples with and without the DOM were treated according to the groups (n = 20 with DOM and 20 without DOM/group): TiF4 varnish (2...
2017: Caries Research
https://www.readbyqxmd.com/read/28501863/psychometric-properties-of-the-revised-illness-perception-questionnaire-for-oral-health
#14
Fredy H Villalobos-Galvis, Ana C Mafla, William F Burbano-Trujillo, Alexandra A Sanchez-Figueroa
AIMS: The aim of this study was to test the hypothesis that, for patients with dental caries, the Spanish version of the Revised Illness Perception Questionnaire for Oral Health (IPQ-R-OH) has 7 dimensions, including personal and treatment control, timeline-acute/chronic and timeline-cyclical, illness coherence, consequences, and emotional representations. METHODS: A Spanish adaptation of the IPQ-R, with a self-reported 38-item scale, was developed. Exploratory and confirmatory factor analyses were conducted using data from 520 patients with dental caries attending the Dental Clinic at Universidad Cooperativa de Colombia, Pasto, Colombia...
2017: Caries Research
https://www.readbyqxmd.com/read/28501859/molecular-insights-into-covalently-stained-carious-dentine-using-solid-state-nmr-and-tof-sims
#15
Ulrica S Almhöjd, Peter Lingström, Åke Nilsson, Jörgen G Norén, Sandra Siljeström, Åsa Östlund, Diana Bernin
Dyes currently used to stain carious dentine have a limited capacity to discriminate normal dentine from carious dentine, which may result in overexcavation. Consequently, finding a selective dye is still a challenge. However, there is evidence that hydrazine-based dyes, via covalent bonds to functional groups, bind specifically to carious dentine. The aim of this study was to investigate the possible formation of covalent bonds between carious dentine and 15N2-hydrazine and the hydrazine-based dye, 15N2-labelled Lucifer Yellow, respectively...
2017: Caries Research
https://www.readbyqxmd.com/read/28445870/klk4-gene-and-dental-decay-replication-in-a-south-brazilian-population
#16
Tayla Cavallari, Simone Tetu Moyses, Samuel Jorge Moyses, Renata Iani Werneck
OBJECTIVE: The objective of this research was to identify and replicate the participation of KLK4 gene polymorphisms in the susceptibility to dental decay. METHODS: A total of 200 patients were recruited using ICDAS criteria - 100 of them with dental caries and 100 with no history of the disease. Buccal cells were collected and the DNA was extracted and amplified using PCR. RESULTS: During the descriptive analysis, the variables ethnicity, biofilm, and gingivitis and the markers rs2242670 and rs2978642 were statistically significant...
2017: Caries Research
https://www.readbyqxmd.com/read/28395292/genes-involved-in-the-enamel-development-are-associated-with-calcium-and-phosphorus-level-in-saliva
#17
Erika Calvano Küchler, Giovana Daniela Pecharki, Myrella Lescio Castro, Junia Ramos, Fernando Barbosa, João Armando Brancher, Alexandre Rezende Vieira, Raquel Fernanda Gerlach, Paula Cristina Trevilatto
Saliva components play a crucial role in the integrity of the dental enamel and in caries susceptibility. The saliva characteristics are controlled by many factors, including genetic factors. Therefore, this study aimed to evaluate the association between the genetic variations in genes expressed in enamel development with calcium and phosphorus levels in saliva. We collected 276 unrelated 12-year-old children from private and public schools. Saliva was collected for DNA extraction from oral cells and for measurement of calcium and phosphorus...
2017: Caries Research
https://www.readbyqxmd.com/read/28391272/in-office-application-of-fluoride-gel-or-varnish-cost-effectiveness-and-expected-value-of-perfect-information-analysis
#18
Falk Schwendicke, Michael Stolpe
Application of fluoride gel/varnish (FG/FV) reduces caries increments but generates costs. Avoiding restorative treatments by preventing caries might compensate for these costs. We assessed the cost-effectiveness of dentists applying FG/FV in office and the expected value of perfect information (EVPI). EVPI analyses estimate the economic value of having perfect knowledge, assisting research resource allocation. A mixed public-private-payer perspective in Germany was adopted. A population of 12-year-olds was followed over their lifetime, with caries increments modelled using wide intervals to reflect the uncertainty of caries risk...
2017: Caries Research
https://www.readbyqxmd.com/read/28359051/postradiation-matrix-metalloproteinase-20-expression-and-its-impact-on-dental-micromorphology-and-radiation-related-caries
#19
Wagner Gomes-Silva, Ana Carolina Prado-Ribeiro, Thaís Bianca Brandão, Karina Morais-Faria, Gilberto de Castro Junior, Milena Perez Mak, Marcio Ajudarte Lopes, Marcelo Marques Rocha, Tuula Salo, Leo Tjäderhane, Mario Fernando de Goes, Alan Roger Santos-Silva
Recent evidence suggests that head-and-neck radiotherapy (HNRT) increases active forms of matrix metalloproteinase-20 (MMP-20) in human tooth crowns, degrading the dentin-enamel junction (DEJ) and leading to enamel delamination, which is a pivotal step in the formation of radiation-related caries (RRC). Additional participation of enzymatic degradation of organic matrix components in caries progression was attributed to MMP-20 in dentin. Therefore, the current study tested the hypothesis that MMP-20 is overexpressed in the DEJ, dentin-pulp complex components, and carious dentin of post-HNRT patients, leading to detectable micromorphological changes to the enamel and dentin...
2017: Caries Research
https://www.readbyqxmd.com/read/28343232/genetic-polymorphisms-in-defb1-and-mirna202-are-involved-in-salivary-human-%C3%AE-defensin-1-levels-and-caries-experience-in-children
#20
Andrea Lips, Leonardo Santos Antunes, Lívia Azeredo Antunes, Júlia Guimarães Barcellos de Abreu, Driely Barreiros, Daniela Silva Barroso de Oliveira, Ana Carolina Batista, Paulo Nelson-Filho, Léa Assed Bezerra da Silva, Raquel Assed Bezerra da Silva, Gutemberg Gomes Alves, Erika Calvano Küchler
The antimicrobial peptides human β-defensins (hBDs) are encoded by β-defensin genes (DEFBs) and are possibly involved in caries susceptibility. In this study we aimed (1) to investigate the relationship between salivary hBDs and caries and (2) to evaluate the association of genetic polymorphisms in DEFB1 and microRNA202 (miRNA202) with salivary levels of hBDs and caries experience. Two data sets were available for this study, totalizing 678 Brazilian children. Dental examination and saliva collection were performed in all included children...
2017: Caries Research
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