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Caries Research

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https://www.readbyqxmd.com/read/29241221/diagnosis-risk-assessment-and-treatment-decisions-for-occlusal-caries-a-survey-from-the-danish-public-dental-health-service
#1
Joana Christina Carvalho, Vibeke Qvist, Nicole R Aimée, Heliana D Mestrinho, Azam Bakhshandeh
This study validates a case-based survey method and analyzes the extent to which Danish dental professionals apply current concepts and strategies for occlusal caries management in children, adolescents, and young adults. A case-based, precoded questionnaire consisting of 10 clinical cases/patients with 26 teeth/occlusal surfaces was developed. The cases were set up in a PowerPoint presentation and color printed as a booklet illustrating patients with different patterns of caries activity, severity, and risk...
December 15, 2017: Caries Research
https://www.readbyqxmd.com/read/29241218/analysis-of-the-cariogenic-potential-of-various-almond-milk-beverages-using-a-streptococcus-mutans-biofilm-model-in-vitro
#2
Janelle Lee, Janice A Townsend, Tatyana Thompson, Thomas Garitty, Arpan De, Qingzhao Yu, Brian M Peters, Zezhang T Wen
To evaluate the cariogenic properties of almond milk beverages, 6 almond milks, along with soy and whole bovine milk, were analyzed for their abilities to support Streptococcus mutans biofilm formation and acid production, and their capacity to buffer changes in pH. Biofilm formation by S. mutans was analyzed using an in vitro 96-well plate model and measured by crystal violet staining. Acid production by S. mutans was evaluated by a colorimetric L-lactate assay and pH measurement of bacterial cultures. Buffering capacity was assessed by a pH titration assay...
December 15, 2017: Caries Research
https://www.readbyqxmd.com/read/29237152/multiple-socioeconomic-factors-and-dental-caries-in-swedish-children-and-adolescents
#3
Ann-Catrin André Kramer, Max Petzold, Magnus Hakeberg, Anna-Lena Östberg
The study aimed to explore associations between multiple socioeconomic factors and dental caries experience in Swedish children and adolescents (3-19 years old). Electronic dental records from 300,988, in a Swedish region (97.3% coverage) were collected using the DMFT indices (decayed, missing, filled teeth: dependent variables). Socioeconomic status (SES) data (ethnicity, wealth, parental education, and employment) for individuals, parents, and families were obtained from official registers. Principal component analysis was used to explore SES data...
December 14, 2017: Caries Research
https://www.readbyqxmd.com/read/29232677/presence-of-initial-caries-lesions-as-a-risk-factor-for-caries-in-preschool-children-a-cohort-study
#4
Renata S Guedes, Chaiana Piovesan, Thiago M Ardenghi, Bruno Emmanuelli, Mariana M Braga, Fausto M Mendes
The aim of this study was to evaluate the influence of initial noncavitated caries lesions on cavitated caries increment in preschool children. A 2-year cohort study was designed to include the participants of a survey on dental caries performed in 2010. Preschool children (12-59 months old) were examined for dental caries and classified as children with no caries lesions, with only initial lesions, with at least 1 moderate caries lesion, and with extensive lesions. Socioeconomic data were also collected. After 2 years, 466 children were re-examined (follow-up rate of 72...
December 13, 2017: Caries Research
https://www.readbyqxmd.com/read/29232675/evaluation-of-novel-anticaries-adhesive-in-a-secondary-caries-animal-model
#5
Tianmu Wu, Bolei Li, Xuedong Zhou, Yao Hu, Huajin Zhang, Yingkang Huang, Hockin H K Xu, Qiang Guo, Mingyun Li, Mingye Feng, Xian Peng, Michael D Weir, Lei Cheng, Biao Ren
We investigated the anticaries properties of an adhesive containing dimethylaminododecyl methacrylate (DMADDM) in vivo via a secondary caries animal model. Cavities were prepared in the maxillary first molars of Wistar rats. DMADDM-containing adhesives were applied on one side and commercial adhesives on the opposite side as a control. After a 3-week feeding period to induce secondary caries, the molars were harvested for the evaluation of the secondary caries. Lesion depth (LD) and mineral loss (ML) were measured via a micro-CT method, and a modified Keyes scoring method yielded scores for the caries lesions...
December 13, 2017: Caries Research
https://www.readbyqxmd.com/read/29232659/phytosphingosine-prevents-the-formation-of-young-salivary-biofilms-in-vitro
#6
Floris J Bikker, Michel A Hoogenkamp, Amine Malhaoui, Kamran Nazmi, Jessica Neilands, Bastiaan P Krom
Dental biofilms are formed in a multistep process that is initiated by the adhesion of oral bacteria to the dental hard surface. As dental biofilms are associated with oral diseases their control is necessary in order to maintain oral health. Recently, it was revealed that phytosphingosine (PHS)-treated hydroxyapatite discs showed anti-adhesive activity in a static in vitro biofilm model against Streptococcus mutans. The goal of the present study was to further unravel the anti-adhesive and anti-biofilm properties of PHS in both static and dynamic in vitro biofilm models against a full salivary inoculum...
December 13, 2017: Caries Research
https://www.readbyqxmd.com/read/29224004/orca-priorities-and-state-of-play-in-2017
#7
Joana Carvalho
No abstract text is available yet for this article.
December 9, 2017: Caries Research
https://www.readbyqxmd.com/read/29224001/dental-caries-and-developmental-defects-of-enamel-in-the-primary-dentition-of-preterm-infants-case-control-observational-study
#8
Ina Manuela Schüler, Stefanie Haberstroh, Kristin Dawczynski, Thomas Lehmann, Roswitha Heinrich-Weltzien
AIM: Assessment of dental health in the primary dentition of preterm infants (PTI) including investigation of mother- and infant-related risk factors in a case-control study design. MATERIAL AND METHODS: One hundred twenty-eight infants aged 3-4 years were included. Sixty-four PTI (27 males) were randomly selected from the preterm registry of the Jena University Hospital. As a control group served 64 full-term infants (FTI) recruited from the Department of Paediatric Dentistry, matched for age and sex...
December 9, 2017: Caries Research
https://www.readbyqxmd.com/read/29207377/polymorphisms-in-nonamelogenin-enamel-matrix-genes-are-associated-with-dental-fluorosis
#9
Erika Calvano Küchler, Carolina Dea Bruzamolin, Marjorie Ayumi Omori, Marcelo C Costa, Leonardo Santos Antunes, Giovana Daniela Pecharki, Paula Cristina Trevilatto, Alexandre Rezende Vieira, João Armando Brancher
The aim of this study was to evaluate whether genetic polymorphisms in AMELX, AMBN, ENAM, TFIP11, and TUFT1 genes are associated with dental fluorosis (DF). A total of 1,017 children from 2 Brazilian cohorts were evaluated. These populations lived in cities with fluoridation of public water supplies. DF was assessed in erupted permanent teeth using the modified Dean index. The polymorphisms rs946252, rs12640848, rs4694075, rs5997096, and rs4970957 were analyzed by real-time PCR from genomic DNA. Associations between DF, genotype, and allele distribution were evaluated using the χ2 test, with an alpha of 5%...
December 6, 2017: Caries Research
https://www.readbyqxmd.com/read/29136625/caries-preventive-effect-of-salt-fluoridation-in-preschool-children-in-the-gambia-a-prospective-controlled-interventional-study
#10
Rainer A Jordan, Andreas Schulte, Alexander C Bockelbrink, Sarah Puetz, Ella Naumova, Lars G Wärn, Stefan Zimmer
The aim of this study was to investigate the anticaries effect of fluoridated salt in a communal feeding program for preschool children. In the Gambian city of Brikama, drinking water had a low fluoride content (0.1 mg F-/L) and young children did not use toothpaste for oral hygiene. Its 2 preschools served as clusters for the trial. Random allocation of the kindergartens was performed by one person not involved in the study, and the clinical examinations were carried out using the envelope method. Meals were prepared with fluoridated salt (250 mg F-/kg salt) in the intervention group but not in the control group...
November 15, 2017: Caries Research
https://www.readbyqxmd.com/read/29059672/lack-of-association-between-bmp2-dlx3-gene-polymorphisms-and-dental-caries-in-primary-and-permanent-dentitions
#11
Jakub Kastovsky, Petra Borilova Linhartova, Kristina Musilova, Lenka Zackova, Martina Kukletova, Lubomir Kukla, Lydie Izakovicova Holla
The aim of this study was to analyze the association between BMP2 (rs1884302) and DLX3 (rs2278163) gene polymorphisms and dental caries in primary and permanent dentitions. A total of 914 subjects were genotyped by the TaqMan methods: 176 caries-free children (with Decayed/Missing/Filled Teeth, DMFT = 0), 542 patients with dental caries in permanent dentition (DMFT ≥1), 83 caries-free children with primary teeth (with decayed/missing/filled teeth, dmft = 0), and 113 children with early childhood caries (ECC, dmft ≥1)...
October 24, 2017: Caries Research
https://www.readbyqxmd.com/read/29055958/streptococcus-mutans-in-mother-child-dyads-and-early-childhood-caries-examining-factors-underlying-bacterial-colonization
#12
Elizabeth L Costa, José F Costa, Matheus P Santos, Lorena L C Ladeira, Rubenice A Silva, Cecília C C Ribeiro
This study investigated the association between colonization of mother-child dyads with Streptococcus mutans (SM) and early childhood caries (ECC), with consideration of the mediator and confounders, using a theoretical model. Four hundred mothers and their children from São Luís, Brazil, were included in the study. A diagram based on directed acyclic graphs was elaborated to analyze the association between SM colonization of the mother, mediated by child SM, and ECC. Other maternal (socioeconomic, waist circumference, sugar consumption, DMFT index, and visible plaque) and child factors (sugar consumption, visible plaque, and child age) composed the theoretical model...
October 21, 2017: Caries Research
https://www.readbyqxmd.com/read/29040975/consensus-statements
#13
David Beighton
No abstract text is available yet for this article.
October 18, 2017: Caries Research
https://www.readbyqxmd.com/read/29024928/zinc-inhibits-collagenolysis-by-cathepsin-k-and-matrix-metalloproteinases-in-demineralized-dentin-matrix
#14
Pinar Altinci, Roda Seseogullari-Dirihan, Gulsen Can, David Pashley, Arzu Tezvergil-Mutluay
The enzymatic degradation of dentin organic matrix occurs via both the action of matrix metalloproteinases (MMPs) and cysteine cathepsins (CCs). Zinc can prevent collagen hydrolysis by MMPs. However, its effect on the activity of dentin-bound CCs is not known. The aim of this study was to investigate the effect of zinc on matrix-bound cathepsin K and MMP activity in dentin. Completely demineralized dentin beams were divided into test groups (n = 9) and incubated at 37°C in an incubation media (1 mL) containing ZnCl2 of 0...
October 13, 2017: Caries Research
https://www.readbyqxmd.com/read/29024927/identifying-a-potential-summary-measure-for-overall-caries-level-in-children-examined-with-the-international-caries-detection-and-assessment-system
#15
Mohamed ElSalhy, Aishah Alsumait, Hollis Lai, José Manuel Almerich-Silla, Chaiana Piovesan, Carlos Flores-Mir, Maryam Amin
OBJECTIVE: To identify a potential summative summary measure that reflects a patient's overall caries level in children examined with the International Caries Detection and Assessment System (ICDAS). SUBJECTS AND METHODS: Participants were 1- to 15-year-old children from Kuwait, Brazil, and Spain. Children's teeth were examined using the ICDAS. Multiple measures of central tendency and dentition-specific indices were considered as potential summative measures. The relationship between the summative measures and number of caries lesions was evaluated considering degrees of caries severity using Spearman's correlation analysis...
October 13, 2017: Caries Research
https://www.readbyqxmd.com/read/29020673/mechanism-of-action-of-tif4-on-dental-enamel-surface-sem-edx-koh-soluble-f-and-x-ray-diffraction-analysis
#16
Lívia P Comar, Beatriz M Souza, Luana P Al-Ahj, Jessica Martins, Larissa T Grizzo, Isabelle S Piasentim, Daniela Rios, Marília Afonso Rabelo Buzalaf, Ana Carolina Magalhães
This in vitro study aimed to evaluate the action of TiF4 on sound and carious bovine and human enamel. Sound (S) and pre-demineralised (DE) bovine and human (primary and permanent) enamel samples were treated with TiF4 (pH 1.0) or NaF varnishes (pH 5.0), containing 0.95, 1.95, or 2.45% F for 12 h. The enamel surfaces were analysed using SEM-EDX (scanning electron microscopy/energy-dispersive X-ray spectroscopy) (n = 10, 5 S and 5 DE) and KOH-soluble fluoride was quantified (n = 20, 10 S and 10 DE). Hydroxyapatite powder produced by precipitation method was treated with the corresponding fluoride solutions for 1 min (n = 2)...
October 12, 2017: Caries Research
https://www.readbyqxmd.com/read/28972954/silver-diamine-fluoride-has-efficacy-in-controlling-caries-progression-in-primary-teeth-a-systematic-review-and-meta-analysis
#17
Ana Cláudia Chibinski, Letícia Maíra Wambier, Juliana Feltrin, Alessandro Dourado Loguercio, Denise Stadler Wambier, Alessandra Reis
A systematic review was performed to evaluate the efficacy of silver diamine fluoride (SDF) in controlling caries progression in children when compared with active treatments or placebos. A search for randomized clinical trials that evaluate the effectiveness of SDF for caries control in children compared to active treatments or placebos with follow-ups longer than 6 months was performed in PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library, and grey literature. The risk of bias tool from the Cochrane Collaboration was used for quality assessment of the studies...
October 4, 2017: Caries Research
https://www.readbyqxmd.com/read/28968608/in-vitro-validation-of-quantitative-light-induced-fluorescence-for-the-diagnosis-of-enamel-fluorosis-in-permanent-teeth
#18
D M Cuevas-Espinosa, E A Martinez-Mier, M Ando, G A Castiblanco, F Cortes, C M Rincon-Bermudez, S Martignon
This study aimed to validate quantitative light-induced fluorescence (QLF) as a diagnostic tool for mild and moderate enamel fluorosis in permanent teeth, comparing it to visual diagnosis and histological assessment completed using polarized light microscopy (PLM). The buccal surfaces of 139 teeth were visually classified using the Thylstrup and Fejerskov Index (TFI) into sound (TFI 0; n = 17), mild (TFI 1-2; n = 69), and moderate (TFI 3-4; n = 43) fluorosis. Fluorosis was then assessed with QLF (variables ΔF, A, and ΔQ at 5-, 15-, and 30-radiance thresholds) using as reference areas the entire surface and a region of interest (ROI), identified as the most representative region of a fluorosis lesion...
October 3, 2017: Caries Research
https://www.readbyqxmd.com/read/28968606/caries-assessment-spectrum-and-treatment-cast-a-novel-epidemiological-instrument
#19
Soraya Coelho Leal, Ana Paula Dias Ribeiro, Jo E Frencken
Caries detection is fundamental to understanding the oral health status of a population and is the basis for caries diagnosis for individual patients. Although different caries detection/diagnosis criteria are available, none of them include the total spectrum of dental caries (which ranges from a sound tooth to a tooth lost due to caries) other than the Caries Assessment Spectrum and Treatment (CAST) instrument. The CAST codes and descriptions were submitted to experienced epidemiologists from across the world for obtaining face and content validity...
October 3, 2017: Caries Research
https://www.readbyqxmd.com/read/28965113/factors-influencing-the-competition-between-streptococcus-oligofermentans-and-streptococcus-mutans-in-dual-species-biofilms
#20
Xudong Bao, Jingmei Yang, J J de Soet, Hongyan Liu, Xuejun Gao, Cor van Loveren, Dongmei Deng
Previous studies have shown that Streptococcus oligofermentans inhibits the growth of cariogenic Streptococcus mutans in biofilms in vitro and is considered a probiotic candidate for caries prevention. This study aimed to examine the effects of various environmental factors on the competition between S. oligofermentans and S. mutans in a dual-species biofilm model. Single or dual S. oligofermentans and S. mutans biofilms were grown in a 96-well active attachment model for 48 h. Several growth conditions were examined in the model, namely: S...
September 30, 2017: Caries Research
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