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Caries Research

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April 19, 2018: Caries Research
Alice S Pinto, Luana Severo Alves, Marisa Maltz, Cristiano Susin, Julio Eduardo A Zenkner
This cross-sectional study assessed the relationship between fixed orthodontic treatment duration and caries activity. Two hundred and sixty 10- to 30-year-olds were divided into 4 groups (n = 65): no fixed orthodontic appliances (G0), orthodontic treatment for 1 year (G1), 2 years (G2), or 3 years (G3). Orthodontic treatment duration was significantly associated with active caries: prevalence was 1.5% for G0, 27.7% for G1, and 72.3% for G2 and G3; the median number of lesions was 0 for G0 and G1 and 2 for G2 and G3...
April 17, 2018: Caries Research
Audrey C C Hollanders, Nicolien K Kuper, Tamires T Maske, Marie-Charlotte D N J M Huysmans
In situ caries research serves as a bridge between clinical research and laboratory studies. In this kind of research, volunteers wear a removable intraoral splint or prosthesis containing research samples. Many different in situ models exist to investigate secondary caries. This systematic review compared currently existing secondary caries models and their lesion progression per day values. MATERIALS AND METHODS: Three databases (Medline, Embase, and Cochrane) were searched for relevant literature...
April 5, 2018: Caries Research
Hyo-Jung Oh, Hyeon-Mi Choi, Chonghyuck Kim, Jae-Gyu Jeon
Water fluoridation has been cited as one of the top 10 public health achievements of the 20th century. Herein, we analyzed water fluoridation articles related to dental caries published in PubMed between 1950 and 2016 using informetrics and linguistic methods to investigate trends in the studies. To this aim, queries such as "dental caries and (water fluoridation or fluoridated water)," "dental caries and (fluoride or fluoridation)," and "dental caries" were submitted to PubMed to retrieve information about articles on water fluoridation within the area of dental caries and fluoride - their titles, abstracts, publication dates, author affiliations, and publication journals...
April 4, 2018: Caries Research
Fabian Cieplik, Fabian Wimmer, Denise Muehler, Thomas Thurnheer, Georgios N Belibasakis, Karl-Anton Hiller, Tim Maisch, Wolfgang Buchalla
Antimicrobial photodynamic therapy (aPDT) may be useful as a supportive antimicrobial measure for caries-active subjects. In this study, the antimicrobial efficacy of aPDT with a phenalen-1-one photosensitizer was evaluated in a novel in vitro biofilm model comprising Actinomyces naeslundii, Actinomyces odontolyticus, and Streptococcus mutans and was compared to chlorhexidine. The proposed biofilm model allows high-throughput screening for antimicrobial efficacy while exhibiting a differentiated response to different antimicrobial approaches...
April 4, 2018: Caries Research
Danika Downey, Joseph Dennison, George J Eckert, Susan E Flannagan, Gisele F Neiva, Peter Yaman, Carlos González-Cabezas
The aim of this study was to evaluate the fluoride release from differently formulated 5% NaF varnishes into unstimulated whole saliva in vivo. The fluoride concentration in unstimulated whole saliva was determined after the application of 3 different 5% NaF varnishes (5% NaF, 5% NaF + tricalcium phosphate [TCP], and 5% NaF + amorphous calcium phosphate [ACP]) or a placebo. Fifteen subjects were recruited and enrolled following Institutional Review Board approval based upon the inclusion/exclusion criteria of this study...
April 3, 2018: Caries Research
Bruna L P Moro, Tatiane F Novaes, Laura R A Pontes, Thais Gimenez, Juan S Lara, Daniela P Raggio, Mariana M Braga, Fausto M Mendes
We aimed to evaluate whether children's caries experience exerts an influence on the performance of visual and radiographic methods in detecting nonevident proximal caries lesions in primary molars. Eighty children (3-6 years old) were selected and classified as having a lower (≤3 decayed, missing, or filled surfaces; dmf-s) or higher (> 3 dmf-s) caries experience. Two calibrated examiners then assessed 526 proximal surfaces for caries lesions using visual and radiographic methods. As a reference standard, 2 other examiners checked the surfaces after temporary separation...
March 22, 2018: Caries Research
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No abstract text is available yet for this article.
March 22, 2018: Caries Research
Kim Rud Ekstrand, Thais Gimenez, Fernanda R Ferreira, Fausto M Mendes, Mariana M Braga
The aims of this study were: (1) to evaluate the overall reproducibility and accuracy of the International Caries Detection and Assessment System (ICDAS) for assessing coronal caries lesions, and (2) to investigate the use of systems associated with the ICDAS for activity assessment of coronal caries lesions. Specific search strategies were adopted to identify studies published up to 2016. For the first objective, we selected studies that assessed primary coronal caries lesions using the ICDAS as a reference standard...
March 8, 2018: Caries Research
Meng-Ying Mao, Meng Li, Lei Lei, Jia-Xin Yin, Ying-Ming Yang, Tao Hu
Streptococcus mutans is an important factor in the etiology and pathogenesis of dental caries, largely owing to its ability to form a stable biofilm. Previous animal studies have indicated that rnc could decrease the amount of sulcal caries, and that the downregulation of cariogenicity might be due to its capacity to disrupt biofilm formation. However, the biofunctions by which rnc is involved in biofilm formation remain to be elucidated. In this study, we further investigate the role of rnc based on the study of mature biofilm...
March 6, 2018: Caries Research
Even A Taira, Talita M S Ventura, Luiza P S Cassiano, Cintia M S Silva, Tatiana Martini, Aline L Leite, Daniela Rios, Ana Carolina Magalhães, Marília Afonso Rabelo Buzalaf
OBJECTIVE: Changes in the protein profile of acquired enamel pellicles (AEP) formed in vivo over different time periods were evaluated after the application of hydrochloric acid (HCl). METHODS: Nine subjects were submitted to dental prophylaxis with pumice. After 3 or 120 min, the teeth were isolated with cotton rolls and 50 μL of 0.1 M HCl (pH 1.0), 0.01 M HCl (pH 2.0), or deionized water were applied on the buccal surface of the teeth for 10 s. The AEP was then collected using an electrode filter paper presoaked in 3% citric acid...
March 6, 2018: Caries Research
Ana Paula C A Beltrame, Dakota Suchyta, Islam Abd Alraheam, Anas Mohammed, Mark Schoenfisch, Ricardo Walter, Izabel C S Almeida, Liliete C Souza, Patricia A Miguez
The aim of this study was to evaluate the antierosive effect of phosphorylated chitosan in dentin. Bovine dentin specimens were randomly distributed into the following groups: (1) no treatment (NoTx/negative control), (2) phosphate-buffered saline solution (PBS), (3) AmF/NaF/SnCl2 (positive control), (4) 0.5% chitosan solution (Chi), (5) 0.5% neutral phosphorylated (NP)-Chi, and (6) 0.5% alkaline phosphorylated (AP)-Chi. The specimens were submitted to de-remineralization treatment cycles for 5 days: 0.5% citric acid (2 min), remineralizing solution (30 min), and surface treatment according to assigned groups (2 min, 6×/day)...
March 6, 2018: Caries Research
Amel Slimani, Delphine Tardivo, Ivan V Panayotov, Bernard Levallois, Csilla Gergely, Frederic Cuisinier, Hervé Tassery, Thierry Cloitre, Elodie Terrer
Dentin carious lesion is a dynamic process that involves demineralization and collagen denaturation. Collagen type I is the major protein in dentin and it has been investigated based on its optical properties. Multiphoton microscopy (MPM) is a nonlinear imaging technique that reveals the caries process using the collagen two-photon excitation fluorescence (2PEF) and its second-harmonic generation (SHG). Combining the histological and the International Caries Detection and Assessment System (ICDAS) classifications with nonlinear optical spectroscopy (NLOS), 2PEF and SHG intensities of enamel and dentin were highly altered during the caries process...
March 6, 2018: Caries Research
Vita Machiulskiene, Joana Christina Carvalho
Classifications employed to measure dental caries should first of all reflect the dynamics of the disease, in order to provide a solid basis for subsequent treatment decisions and for further monitoring of dental health of individual patients and populations. The contemporary philosophy of dental caries management implies that nonoperative treatment of caries lesions should be implemented whenever possible, limiting operative interventions to the severe and irreversible cases. The ORCA Saturday Afternoon Symposium 2016, held back-to-back to the 63rd ORCA Congress in Athens, Greece, was intended to provide an update on general requirements for clinical caries diagnosis and to overview caries diagnostic classifications including their rationale, validation, advantages, and limitations...
March 5, 2018: Caries Research
Bente Nyvad, Vibeke Baelum
The Nyvad classification is a visual-tactile caries classification system devised to enable the detection of the activity and severity of caries lesions with special focus on low-caries populations. The criteria behind the classification reflect the entire continuum of caries, ranging from clinically sound surfaces through noncavitated and microcavitated caries lesions in enamel, to frank cavitation into the dentin. Lesion activity at each severity stage is discriminated by differences in surface topography and lesion texture...
March 5, 2018: Caries Research
Amid I Ismail, Marisol Tellez, Nigel B Pitts
No abstract text is available yet for this article.
March 5, 2018: Caries Research
Michèle Muller-Bolla, Fréderic Courson, Laurence Lupi-Pégurier, Corinne Tardieu, Shrisha Mohit, Pascal Staccini, Ana Miriam Velly
A split-mouth randomized clinical trial was carried out to assess the effectiveness of sealants in preventing carious ICDAS (International Caries Detection and Assessment System) 3-6 lesions within a 2-year follow-up. We evaluated the effectiveness of 2 types of resin-based sealants, with and without fluoride, their retention rates, and the caries risk factors related to their outcomes. The study included 663 tooth pairs in 400 children (aged 5-15 years) considered to be at high individual caries risk (ICR) and presenting permanent molars free of caries or affected by ICDAS 1-2 lesions...
March 1, 2018: Caries Research
Alex Man Him Chau, Edward Chin Man Lo, May Chun Mei Wong, Chun Hung Chu
Oral epidemiology involves studying and investigating the distribution and determinants of dental-related diseases in a specified population group to inform decisions in the management of health problems. In oral epidemiology studies, the hypothesis is typically followed by a cogent study design and data collection. Appropriate statistical analysis is essential to demonstrate the scientific association between the independent factors and the target variable. Analysis also helps to develop and build a statistical model...
February 23, 2018: Caries Research
Samilly Evangelista Souza, Aline Araújo Sampaio, Altair Antoninha Del Bel Cury, Yuri Wanderley Cavalcanti, Antônio Pedro Ricomini Filho, Jaime Aparecido Cury
Since there is no consensus about whether starch increases the cariogenic potential of sucrose, we used a validated 3-species biofilm model to evaluate if starch combined with sucrose provokes higher root dentine demineralization than sucrose alone. Biofilms (n = 18) composed by Streptococcus mutans (the most cariogenic bacteria), Actinomces naeslundii (which has amylolytic activity), and Streptococcus gordonii (which binds salivary amylase) were formed on root dentine slabs under exposure 8 ×/day to one of the following treatments: 0...
February 14, 2018: Caries Research
Camila A Zamperini, Ana K Bedran-Russo
This study investigated the remineralization effect of experimental mint formulations containing bioactive agents (xylitol; green tea extract, GT; and amorphous calcium phosphate, ACP) in the progression of artificially induced root caries. Root caries lesions were induced by demineralization solution (pH 4.6; 96 h; 37°C). The lesions were treated with mint A, mint B, mint C, xylitol, GT, ACP, or remineralization solution (RS; negative control). Specimens were pH-cycled through treatments (5×/day; 3 min) and 6 cycles of acidic (pH 5...
February 8, 2018: Caries Research
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