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Surgical Clinics of North America

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https://www.readbyqxmd.com/read/28501257/preface
#1
EDITORIAL
Sean J Langenfeld
No abstract text is available yet for this article.
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501256/foreword
#2
EDITORIAL
Ronald F Martin
No abstract text is available yet for this article.
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501255/molecular-markers-for-colorectal-cancer
#3
REVIEW
Moriah Wright, Jenifer S Beaty, Charles A Ternent
Colorectal cancers develop through at least 3 major pathways, including chromosomal instability, mismatch repair, and methylator phenotype. These pathways can coexist in a single individual and occur in both sporadic and inherited colorectal cancers. In spite of the unique molecular and genetic signatures of colorectal cancers, nonspecific chemotherapy based on the antineoplastic effects of 5-fluorouracil is the cornerstone of therapy for stage III and some stage II disease. Techniques to recognize colorectal cancer at the molecular level have facilitated development of new signature drugs designed to inhibit the unique pathways of colorectal cancer growth and immunity...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501254/cytoreduction-and-hyperthermic-intraperitoneal-chemotherapy-in-the-management-of-colorectal-peritoneal-metastasis
#4
REVIEW
Bradley Hall, James Padussis, Jason M Foster
Historically, patients with peritoneal carcinomatosis secondary to colorectal cancer have a poor overall prognosis. Recent data support the use of cytoreductive surgery and heated intraperitoneal chemotherapy (CRS + HIPEC) to specifically address the peritoneal disease. Retrospective studies on CRS + HIPEC have been promising, showing significant improvements in OS compared with systemic chemotherapy alone. However, CRS + HIPEC carries morbidity similar to other advance oncology procedures such as liver resection and pancreatoduonectomy...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501253/resection-of-the-primary-tumor-in-stage-iv-colorectal-cancer-when-is-it-necessary
#5
REVIEW
Leandro Feo, Michael Polcino, Garrett M Nash
Management of metastatic colorectal cancer requires accurate staging and multidisciplinary evaluation, leading to a consensus treatment plan with the ultimate goal of increasing survival and improving the quality of life, while taking into consideration the patient's performance status, disease burden, and goals of care. Since the introduction of multidrug chemotherapeutic regimens, survival of patients with metastatic colorectal cancer has improved. Many patients with unresectable disease are undergoing surgery for asymptomatic primary tumors despite evidence that it is usually a futile intervention...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501252/atypical-colorectal-neoplasms
#6
REVIEW
Michael G Porter, Scott M Stoeger
Primary colorectal lymphoma, carcinoids (neuroendocrine tumors), and gastrointestinal stromal tumors comprise a small subset of all colorectal cancers. Their features are unique, and their treatment varies from that of colorectal adenocarcinoma. Appropriate identification is key in the management of these tumors.
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501251/dysplasia-and-cancer-in-inflammatory-bowel-disease
#7
REVIEW
Lyen C Huang, Amit Merchea
Inflammatory bowel disease is associated with an increased risk of dysplasia and cancer. Improvements in medical management and endoscopic surveillance have reduced these risks. Patients can develop cancer even in the absence of dysplasia or with indefinite or low-grade dysplasia. Most guidelines recommend starting surveillance colonoscopy 6 to 10 years after initial diagnosis with interval surveillance afterward every 1 to 5 years depending on risk and/or individual characteristics. Most patients should undergo total proctocolectomy with end ileostomy or reconstruction with ileal pouch anal anastomosis because segmental and subtotal resections carry a higher risk of metachronous cancers...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501250/hereditary-colorectal-cancer-syndromes
#8
REVIEW
Katerina Wells, Paul E Wise
Awareness of hereditary colorectal cancer syndromes is important to facilitate their identification because affected patients are at increased risk for early onset, synchronous, and metachronous colorectal malignancies, and certain extracolonic malignancies depending on the syndrome. Identification of an affected individual allows for screening and early interventions for patients and their at-risk kindred. Genetic counseling and testing is important to the care of these patients. As knowledge of the genetic basis of these syndromes grows, unique genotype-phenotype profiles allow clinicians to tailor surveillance and treatment strategies based on individual risk...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501249/new-strategies-in-rectal-cancer
#9
REVIEW
Guilherme Pagin São Julião, Angelita Habr-Gama, Bruna Borba Vailati, Sergio Eduardo Alonso Araujo, Laura Melina Fernandez, Rodrigo Oliva Perez
In recent years, our understanding of rectal cancer has improved, including how locally advanced disease responds to chemotherapy and radiation. This has led to new innovations and advances in the treatment of rectal cancer, which includes organ-preserving strategies for responsive disease, and minimally invasive approaces for the performance of total mesorectal excision/protectomyh for persistently advanced disease. This article discusses new strategies for rectal cancer therapy, including Watch and Wait, local excision, minimally invasive proctectomy, and transanal total mesorectal excision particularly in the setting of preoperative multimodality treatment...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501248/local-excision-of-rectal-cancer
#10
REVIEW
Daniel Owen Young, Anjali S Kumar
Local excision (LE) of early-stage rectal cancer avoids the morbidity associated with radical surgery but has historically been associated with inferior oncologic outcomes. Newer techniques, including transanal endoscopic microsurgery (TEM) and transanal minimally invasive surgery (TAMIS), have been developed to improve the quality of LE and extend the benefits of LE to tumors in the more proximal rectum. This article provides an overview of conventional LE, TEM, and TAMIS techniques, including indications for their use and pertinent literature on their associated outcomes for rectal cancer...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501247/robotic-colorectal-surgery-for-neoplasia
#11
REVIEW
Ajit Pai, Slawomir Marecik, John Park, Leela Prasad
Robotic colorectal surgery has become increasingly prevalent, with several reported benefits for surgeons and patients alike. Although its use is well-supported for pelvic surgery, there is less evidence that it is beneficial for abdominal surgery. There are several technical limitations of robotic surgery, and newer generations of robot platforms have addressed these, which may lead to increased use in the near future. In general, robotic surgery is more beneficial for surgeons than it is for patients.
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501246/advances-in-laparoscopic-colorectal-surgery
#12
REVIEW
James Michael Parker, Timothy F Feldmann, Kyle G Cologne
Laparoscopic colorectal surgery has now become widely adopted for the treatment of colorectal neoplasia, with steady increases in utilization over the past 15 years. Common minimally invasive techniques include multiport laparoscopy, single-incision laparoscopy, and hand-assisted laparoscopy, with the choice of technique depending on several patient and surgeon factors. Laparoscopic colorectal surgery involves a robust learning curve, and fellowship training often lays the foundation for a high-volume laparoscopic practice...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501245/emergency-presentations-of-colorectal-cancer
#13
REVIEW
Canaan Baer, Raman Menon, Sarah Bastawrous, Amir Bastawrous
Many colorectal carcinomas will present emergently with issues such as obstruction, perforation, and bleeding. Emergency surgery is associated with poor short- and long-term outcomes. For abnormality localizing to the colon proximal to the splenic flexure, surgical management with hemicolectomy is often a safe and appropriate approach. Obstructions are more common in the distal colon, however, where there is an evolving spectrum of surgical and nonsurgical options, most notably by the development of endoluminal stents...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501244/the-difficult-colorectal-polyp
#14
REVIEW
Mark J Pidala, Marianne V Cusick
Difficult colorectal polyps represent lesions that pose a challenge to traditional endoscopic snare polypectomy. These polyps have historically been managed by surgical resection. Currently, several less invasive options are available to avoid colectomy. Repeat colonoscopy and snare polypectomy by an expert endoscopist, endoscopic mucosal resection, endoscopic submucosal dissection, and combined endoscopic and laparoscopic surgery have been developed to remove difficult polyps without the need for formal surgical resection...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501243/imaging-for-colorectal-cancer
#15
REVIEW
Yosef Nasseri, Sean J Langenfeld
A comprehensive approach to colorectal cancer includes thorough radiologic imaging, which allows appropriate initial staging of the disease, as well as subsequent surveillance for disease recurrence. Several imaging modalities are used with different associated advantages and disadvantages, which are outlined in this article with specific attention paid to the local staging of rectal cancer.
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28501242/colorectal-cancer-screening
#16
REVIEW
Jesse Samuel Moore, Tess Hannah Aulet
This article highlights the importance of colorectal cancer screening in the prevention and early detection of colorectal cancer. Early detection of colorectal cancer is associated with reduced mortality. There are a variety of screening procedures for colorectal cancer, which are variable in technique and effectiveness. Engaging patients to participate in a screening regimen with which they will comply is critical to the ultimate success of colorectal cancer screening. Familiarity with risk stratification and screening guidelines is imperative for counseling and appropriate testing...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28325200/gastric-neoplasms
#17
EDITORIAL
Kelly L Olino, Douglas S Tyler
No abstract text is available yet for this article.
April 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28325199/foreword
#18
EDITORIAL
Ronald F Martin
No abstract text is available yet for this article.
April 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28325198/the-evaluation-and-management-of-suspicious-gastric-lesions-following-bariatric-surgery
#19
REVIEW
Guillermo Gomez
Obesity has reached epidemic proportions worldwide and is associated with a higher mortality from several diseases, including adenocarcinoma of the esophagus and of the gastric cardia. Increased body mass index is associated with an increased incidence of gastroesophageal reflux disease (GERD), Barrett metaplasia, and adenocarcinoma of the cardia. Bariatric surgery remains the most effective therapy for morbid obesity and has the potential to improve weight-related GERD. A high index of suspicion is paramount for early detection of foregut neoplasia after bariatric surgery...
April 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28325197/east-versus-west-differences-in-surgical-management-in-asia-compared-with-europe-and-north-america
#20
REVIEW
Tomio Ueno, Michihisa Iida, Shigefumi Yoshino, Shigeru Takeda, Hisako Kubota, Masaharu Higashida, Yasuo Oka, Atushi Tsuruta, Hideo Matsumoto, Hiroaki Nagano
In recent decades, there has been considerable worldwide progress in the treatment of gastric cancer. Gastrectomy with a modified D2 lymphadenectomy (sparing the distal pancreas and spleen) has increasingly gained acceptance as a preferable standard surgical approach among surgeons in the East and the West. Despite growing consensus significant differences still exist in surgical techniques in clinical trials and clinical practices secondary to variations in epidemiology, clinicopathologic features, and surgical outcomes among geographic regions...
April 2017: Surgical Clinics of North America
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