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Bratislavské Lekárske Listy

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https://www.readbyqxmd.com/read/27826980/on-the-problems-of-the-so-called-afternoon-diabetes
#1
M Zuffa
No abstract text is available yet for this article.
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826979/the-anti-inflammatory-and-antioxidant-effects-of-thymoquinone-on-ceruleine-induced-acute-pancreatitis-in-rats
#2
A Dur, H Kose, A Kocyigit, O Kocaman, M Ismayilova, F C Sonmez
INTRODUCTION: The aim of this study is to investigate the potential antioxidant and anti-inflammatory effects of thymoquinone (TQ) on ceruleine induced acute pancreatitis. MATERIAL AND METHODS: A total of 14 male Wistar albino rats were divided into 2 groups as follows: (1) normal saline-treated group and (2) thymoquinone- treated groups. For achieving acute pancreatitis, intraperitoneal (IP) cerulein, a stable cholecystokinin (CCK) analogue, was applied in a 50 mcg/kg dose 2 times in one-hour interval in total...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826978/in-vitro-expression-of-hpv16-e7-linked-to-hmgb1-immunoadjuvant-in-mammalian-cells
#3
S Talebi, A Bolhassani, T Mokhtari Azad, A Arashkia, M H Modaresi
BACKGROUND: E7 is the major transforming protein of human papillomavirus (HPV) that plays important role in maintaining the proliferative state in HPV-infected cells. Furthermore, high mobility group 1 protein (HMGB1) is a highly conserved component of chromatin that can be secreted by macrophages and activated monocytes and thus functions as an inflammation mediator. METHODS: In the current study, cloning of HMGB1 gene and also HPV16E7-HMGB1 was performed in pEGFP-N1 eukaryotic expression vector in order to evaluate their expression in mammalian cells...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826977/does-standard-post-operative-rehabilitation-have-its-place-after-total-knee-replacement
#4
M Vavro, E Ziakova, K Gazdikova, D Farkasova
OBJECTIVE: The pilot study objective was to evaluate the effect of comprehensive post-operative physiotherapeutic treatment on the selected physiotherapeutic parameters as well as patients' quality of life after a total knee joint replacement surgery. RESULTS: Thirty patients after total knee joint arthroplasty were enrolled into the pilot study. After completing the physiotherapeutic processes, we have observed among the patients who underwent a total knee replacement surgery, a significant increase in muscle strength as with the flexors as well as the extensors (p = 0...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826976/patients-with-klippel-trenaunay-syndrome
#5
M Zavacka, J Pobehova, K Gibarti, M Frankovicova
Klippel-Trenaunay syndrome is the most frequent systemic venous angiodysplasia. It is characterized by cutaneous capillary malformations - naevus flammeus, excessive growth of soft and bone tissue, venous and lymphatic malformations. Investigative methods include: clinical examinations, venography as the evidence of dysplastic changes of superficial and / or deep venous system, the Moyne obstruction and venous insufficiency perforator. Treatment is conservative, related to that of chronic venous disease. The surgery is aimed at removing the varices and insufficient perforators (Fig...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826975/treatment-of-lower-extremity-superficial-vein-thrombosis-with-low-molecular-weight-heparin
#6
A Dzupina, M Wald, B B Lee, V Stvrtinova
AIM: The aim of our study was to ascertain the efficacy of low-molecular-weight heparin (LMWH) in the treatment of patients with SVT. MATERIAL AND METHODS: A group of 336 outpatients with clinical diagnosis of SVT was evaluated in this prospective study. At the beginning of the study all patients were examined by clinical investigation, laboratory tests and duplex ultrasound investigation (examination). All patients included into the study were treated with LMWH...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826974/can-n-terminal-pro-b-type-natriuretic-peptide-neutrophil-to-lymphocyte-ratio-c-reactive-protein-help-to-predict-short-and-long-term-mortality
#7
I Ozmen, Z Karakurt, C Salturk, F Kargin, H B Takir, E Aksoy, R Sari, E Celik, E A Tuncay, E Yildirim, O Y Mocin, N Adiguzel, S Oztas, S Gungor, G Gungor
BACKGROUND: There is limited data about ICU, short and long-term mortality prediction of severe CAP with neutrophil-to-lymphocyte ratio (NLR): N-terminal proB- type natriuretic peptide (NT-proBNP): C-reactive protein (CRP). AIM: Besides the known severity indexes of ICU, can NLR, NT-proBNP, CRP predict ICU, short and long term mortality? METHODS: A retrospective cohort study was carried out in a level III ICU of a tertiary training hospital for chest diseases and thoracic surgery...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826973/chronic-hypoxia-increases-fetoplacental-vascular-resistance-in-rat-placenta-perfused-with-blood
#8
P Kafka, O Vajnerova, V Hampl
BACKGROUND: Chronic hypoxia elevates vascular resistance on the fetal side of the placenta. However, when a low-viscosity perfusate is used, the increase in resistance caused by chronic hypoxia is relatively small (12 mmHg). In the present study, we tested the hypothesis that perfusion with more viscous fluid (blood) will reveal more substantial effect of chronic hypoxia. METHODS: Using an isolated, dually perfused rat placenta perfused at a constant flow rate with homologous blood, perfusion pressure on the fetal side was measured...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826972/risk-factors-detection-in-chronic-thromboembolic-pulmonary-hypertension-a-tool-for-risk-quantification
#9
M Bohacekova, M Kaldararova, T Valkovicova, A Remkova, J Vesely, I Simkova
BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by chronic thromboembolic obstruction in the pulmonary bed. The definitive pathogenesis remains incompletely explained, although multiple risk factors of CTEPH have been identified. The purpose of the study was to evaluate the risk profile of patients with CTEPH and the representativeness of risk factors, identify possible new CTEPH risk factors and specify the epidemiology of CTEPH in our country. METHODS: In 81 patients with CTEPH, well known risk factors were analyzed, and a detailed analysis of selected hematological parameters was investigated at a specialized hematology laboratory...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826971/predictors-of-blood-pressure-control-in-patients-with-resistant-hypertension
#10
J Pales, G Kamensky, J Payer
BACKGROUND: Uncontrolled resistant hypertension (RH) defined by the mean 24-hour ambulatory blood pressure (ABPM) represents an independent risk factor in hypertensive patients. Predictors of blood pressure (BP) control in RH are not yet clearly defined. OBJECTIVES: To evaluate the predictors of BP control in RH patients with repeated ABPM measurements. METHODS: 114 consecutive patients from outpatient cardiology office fulfilling criteria for RH (office BP ≥ 140 and/or 90 mmHg, with treatment of ≥ 3 antihypertensive drugs, including diuretic, or controlled BP with > 3 drugs), with two consecutive ABPM studies were compared in clinical characteristics according to BP control assessed by ABPM RESULTS: After the second ABPM, BP was controlled in 25...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826970/conservative-versus-invasive-treatment-in-hypertrophic-obstructive-cardiomyopathy-an-echocardiography-study
#11
T Honek, J Krejci, J Machal, L Groch, J Sitar, J Meluzin, L Spinarova
AIM AND METHODS: The aim of our study was to compare the development of echocardiographic parameters and functional status of patients with hypertrophic obstructive cardiomyopathy (HOCM) treated conservatively (n = 41) or by alcohol septal ablation (ASA; n = 39). RESULTS: Left ventricular outflow tract gradient (LVOTG) decreased in the first year by 53.7±36.4 mmHg in ASA group versus 5.5±47.1 mmHg in conservatively treated group (p<0.001), in the third year by 53...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27826969/risk-of-statin-therapy-in-elderly
#12
E Ginter, I Kajaba
No abstract text is available yet for this article.
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677201/body-proportions-as-possible-predictors-for-free-gracilis-one-stage-facial-reanimation
#13
M Bohac, M Palkovic, J Fedeles, J Hodosy
BACKGROUND: Gracilis muscle and its motor nerve belongs to most commonly used flap for facial reanimation. However, it is performed in two steps, which is time consuming. One stage technique can be also performed, but the length of the motor nerve cannot be currently determined before surgery. AIM: The present study was conducted in order to evaluate the body composition on the length and suitability of the motor nerve of gracilis muscle for one stage facial reanimation...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677200/phenytoin-accelerates-tendon-healing-in-a-rat-model-of-achilles-tendon-rupture
#14
B Hajipour, A M Navali, S Ali Mohammad, G Mousavi, M Gahvechi Akbari, T Maleki Miyandoab, L Roshangar, B Mohammadi Saleh, T Asvadi Kermani, F Moutab Laleh, M Ghabili
INTRODUCTION: Tendons are vulnerable to various types of acute or chronic injures. Different methods have been investigated to achieve better healing. Phenytoin is a drug which could stimulate fibroblasts to produce collagen. This experimental study was performed to assess the effect of phenytoin on tendon healing in a rat model of tendon rupture. METHODS: Thirty healthy rats were divided into 3 groups, 1) Sham group; 2) Tendon rupture; 3) Tendon rupture+phenytoin (100 mg/kg intraperitoneally) for 21 days...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677199/dexmedetomidine-protected-copd-induced-lung-injury-by-regulating-mirna-146a
#15
N Li, B S Ouyang, L Liu, C S Lin, D D Xing, J Liu
OBJECTIVE: To study the mechanism of protection provided by dexmedetomidine against COPD-induced lung injury. METHODS: COPD rat model was determined by measuring lung function, and comparing HE staining between two different groups. We got the lung tissue and cells from the control and COPD groups. The cells were divided into three groups: control group, and blank and drug groups that were from the COPD rats. Cell apoptosis, relative gene expression and TNF-α and IL-1β from nutrient solution were measured...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677198/effects-of-beta-glucan-on-protection-of-young-and-aged-rats-from-renal-ischemia-and-reperfusion-injury
#16
M Esrefoglu, O E Tok, M S Aydin, M Iraz, O F Ozer, S Selek, M Iraz
BACKGROUND: Ischemia-reperfusion injury is one of the leading causes of acute renal failure which is a common clinical event leading to development of chronic kidney disease and a high mortality; especially in elderly people. β-glucans are glucose polymer groups with free-radical scavenger, macrophage activator, and immune defense inducer functions. We designed this study to determine the possible protective effects of β-glucan against renal ischemia-reperfusion injury comparatively in young and aged rats...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677197/can-platelet-rich-plasma-be-used-safely-in-intra-abdominal-operations
#17
F Kaya, K Kismet, H Ozer, V G Soylu, M E Duymus, Y A Akgun, A Demir, P Celepli, T Guclu, S Bolat, E Ertas
OBJECTIVES: In this study, it was aimed to investigate whether or not platelet‑rich plasma (PRP) causes intra-abdominal adhesions and therefore, whether or not PRP can be used safely in intra-abdominal operations. METHODS: Of the total of 35 animals, 5 were used as donors for the preparation of platelet‑rich plasma (PRP). The surgical procedures were performed on the remaining 30 animals. These rats were randomized and divided into 3 groups of 10. In Group 1, no adhesion induction was performed...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677196/prevalence-of-helicobacter-pylori-infection-and-its-association-with-lipid-profiles
#18
Y Sun, D Fu, Y K Wang, M Liu, X D Liu
OBJECTIVE: To evaluate the prevalence of Helicobacter pylori (H. pylori, HP) infection in subjects receiving routine physical examination and its associations with age, sex, body mass index (BMI) and lipid profiles. MATERIALS AND METHODS: Clinical information of 22,103 individuals who took routine physical examinations, including that on age, gender, height, weight, triglyceride, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol and data of HP infection were collected and analyzed...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677195/recidivous-cholesteatoma-dwi-mr-after-canal-wall-up-and-canal-wall-down-mastoidectomy
#19
T Bakaj, L Bakaj Zbrozkova, R Salzman, M Tedla, I Starek
OBJECTIVES: To investigate the correlation between preoperative non-echo planar diffusion-weighted (non-EPI DWI) MR imaging with surgical findings of recidivous middle ear cholesteatoma after canal wall up (CWU) and canal wall down (CWD) mastoidectomy. BACKGROUND: The detection of recidive cholesteatoma after CWU and after CWD procedures, when the trepanation cavity is spontaneously closed by soft tissue, is possible by second-look and revision surgery. However, many cases prove to be negative of the disease...
2016: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/27677194/the-effect-of-prostaglandin-induced-labor-and-selected-factors-on-the-occurrence-and-extent-of-birth-canal-injuries
#20
A Kacvinska, M Drab, A Totka, K Holoman, M Gabor
OBJECTIVES: To determine the effect of labor induction using prostaglandin, gestation period and delivery type on the cause and extent of birth-canal injuries. METHODS: A retrospective study based on the records of II. GPK UNB Ružinov. The total set (n = 1377) consisted of patients who went into labor in second half of the year 2014 at this clinic. The research used categorical data divided into groups of factors (induction, week of delivery, type of delivery) and birth injuries...
2016: Bratislavské Lekárske Listy
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