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Lipids

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https://www.readbyqxmd.com/read/28631071/oxidation-of-c18-hydroxy-polyunsaturated-fatty-acids-to-epoxide-or-ketone-by-catalase-related-hemoproteins-activated-with-iodosylbenzene
#1
Tarvi Teder, William E Boeglin, Alan R Brash
Small catalase-related hemoproteins with a facility to react with fatty acid hydroperoxides were examined for their potential mono-oxygenase activity when activated using iodosylbenzene. The proteins tested were a Fusarium graminearum 41 kD catalase hemoprotein (Fg-cat, gene FGSG_02217), a Pseudomonas fluorescens Pfl01 catalase (37.5 kD, accession number WP_011333788.1), and a Mycobacterium avium ssp. paratuberculosis 33 kD catalase (gene MAP-2744c). 13-Hydroxy-octadecenoic acids (which are normally unreactive) were selected as substrates because these enzymes react specifically with the corresponding 13S-hydroperoxides (Pakhomova et al...
June 19, 2017: Lipids
https://www.readbyqxmd.com/read/28631070/lipids-of-the-tail-gland-body-and-muzzle-fur-of-the-red-fox-vulpes-vulpes
#2
Stuart McLean, Noel W Davies, David S Nichols
The tail gland of the red fox (Vulpes vulpes) secretes lipids containing volatile terpenes used in social communication. We have analysed lipids extracted from fur of the tail gland, body (flanks) and muzzle of foxes. GC-MS showed a novel group of iso-valerate and tiglate monoesters of alkane-1,2-diols (C18:0-22:0). There was also a larger group of Type II diesters in which a second, longer chain, fatty acid (FA) was attached to the free alcohol group. LC-MS showed the full range of diol diesters, mostly C36:0-50:0, with smaller amounts of the corresponding mono-unsaturated tiglate esters...
June 19, 2017: Lipids
https://www.readbyqxmd.com/read/28625013/anti-mutagenic-properties-of-mono-and-dienoic-acid-biohydrogenation-products-from-beef-fat
#3
Jeyachchandran Visvalingam, Payam Vahmani, David C Rolland, Michael E R Dugan, Xianqin Yang
Unsaturated fatty acid biohydrogenation products from beef fat and pure fatty acids were subjected to the Ames Salmonella mutagenicity testing, including monounsaturated fatty acids [MUFA: oleic acid, vaccenic acid, elaidic acid; beef fatty acid fractions rich in trans (t)11/t13-t14-18:1 (t11,13,14-Frac), t10-18:1 (t10-Frac)] and dienoic fatty acids [linoleic acid, conjugated linoleic isomers cis (c)9,t11-18:2 and t10,c12-18:2, and a mixed beef dienoic fatty acid fraction high in c9,t13-/t8,c12/t11c15-18:2 (MD)]...
June 17, 2017: Lipids
https://www.readbyqxmd.com/read/28603809/an-ethical-dilemma-to-share-or-not-to-share-your-paper-published-in-lipids-using-an-on-line-outlet
#4
EDITORIAL
Eric J Murphy
No abstract text is available yet for this article.
June 12, 2017: Lipids
https://www.readbyqxmd.com/read/28601955/suksdorfin-promotes-adipocyte-differentiation-and-improves-abnormalities-in-glucose-metabolism-via-ppar%C3%AE-activation
#5
Mari Iwase, Takayuki Yamamoto, Kanako Nishimura, Haruya Takahashi, Shinsuke Mohri, Yongjia Li, Huei-Fen Jheng, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Masahiko Taniguchi, Kimiye Baba, Shigeru Murakami, Teruo Kawada, Tsuyoshi Goto
Although the Apiaceae herb family has been traditionally used for the management of type 2 diabetes, its molecular mechanism has not been clarified. Coumarin derivatives, which are abundant in plants of the Apiaceae family, were evaluated for their effects on adipogenesis. We found that suksdorfin significantly promoted adipocyte differentiation and enhanced production of adiponectin, an anti-diabetic adipokine. We also demonstrated that suksdorfin activates peroxisome proliferator-activated receptor gamma (PPARγ), a master regulator of adipogenesis...
June 10, 2017: Lipids
https://www.readbyqxmd.com/read/28578538/phospholipids-of-new-zealand-edible-brown-algae
#6
Mikhail Vyssotski, Kirill Lagutin, Andrew MacKenzie, Kevin Mitchell, Dawn Scott
Edible brown algae have attracted interest as a source of beneficial allenic carotenoid fucoxanthin, and glyco- and phospholipids enriched in polyunsaturated fatty acids. Unlike green algae, brown algae contain no or little phosphatidylserine, possessing an unusual aminophospholipid, phosphatidyl-O-[N-(2-hydroxyethyl) glycine], PHEG, instead. When our routinely used technique of (31)P-NMR analysis of phospholipids was applied to the samples of edible New Zealand brown algae, a number of signals corresponding to unidentified phosphorus-containing compounds were observed in total lipids...
June 3, 2017: Lipids
https://www.readbyqxmd.com/read/28578537/identification-and-characterization-of-a-novel-thermophilic-organic-solvent-stable-lipase-of-bacillus-from-a-hot-spring
#7
Jiang Li, Xiumeng Liu
A novel lipase gene lip256 was cloned and identified from the genomic library of hot spring strain Bacillus sp. HT19. The deduced amino acid sequence of lip256 has less than 32% identity to a predicted esterase (Cog1752) from Photobacterium leiognathi lrivu.4.1 and contains a novel motif (GTSAG) that differs from other clusters in the lipase superfamily. Following purification, a single band was obtained with a molecular mass of 33 kDa by SDS-PAGE, and the optimal temperature and pH for lipolytic activity of Lip25 were 70 °C and 9...
June 3, 2017: Lipids
https://www.readbyqxmd.com/read/28551706/oral-administration-of-ethanolamine-glycerophospholipid-containing-a-high-level-of-plasmalogen-improves-memory-impairment-in-amyloid-%C3%AE-infused-rats
#8
Shinji Yamashita, Michio Hashimoto, Abdul Md Haque, Kiyotaka Nakagawa, Mikio Kinoshita, Osamu Shido, Teruo Miyazawa
Ethanolamine plasmalogen (PlsEtn), a major phospholipid in neuronal membranes [60-90 mol% of ethanolamine glycerophospholipid (EtnGpl)], is specifically decreased in brains from patients with Alzheimer's disease (AD). The present study investigated how PlsEtn administration affects cognitive deficits and lipid composition in an animal model of AD. AD model rats were infused with amyloid-β (Aβ) into the cerebral ventricle and divided into three groups. Control, Egg, and Ascidian groups were then orally administered vehicle, egg yolk EtnGpl (260 μmol as EtnGpl/kg BW/day; 10 μmol as PlsEtn/kg BW/day), or ascidian viscera EtnGpl (260 μmol as EtnGpl/kg BW/day; 209 μmol as PlsEtn/kg BW/day), respectively...
May 27, 2017: Lipids
https://www.readbyqxmd.com/read/28547181/sequential-feeding-of-lipid-supplement-enriches-beef-adipose-tissues-with-18-3n-3-biohydrogenation-intermediates
#9
P Vahmani, J L Aalhus, D C Rolland, T A McAllister, N Prieto, H C Block, S D Proctor, L L Guan, M E R Dugan
The present study was designed to determine if feeding steers extruded flaxseed and hay (25 and 75%; DM basis) together as a total mixed ration (TMR), or sequentially (non-TMR) would result in different enrichments of polyunsaturated fatty acids (PUFA) and their biohydrogenation intermediates (BHI) in beef adipose tissues [subcutaneous (SC) vs perirenal (PR) fat]. Forty-eight Angus cross steers (325 ± 16 kg) were stratified by weight to six pens, and pens were randomized to either TMR or non-TMR and fed ad libitum for an average of 242 days...
May 25, 2017: Lipids
https://www.readbyqxmd.com/read/28528433/hydrolysis-of-phosphatidylcholine-isoprostanes-ptdcho-ip-by-peripheral-human-group-iia-v-and-x-secretory-phospholipases-a2-spla2
#10
Arnis Kuksis, Waldemar Pruzanski
Biologically active F- and E/D-type-prostane ring isomers (F2-IP and E2/D2-IP, respectively) are produced in situ by non-enzymatic peroxidation of arachidonic acid esterified to GroPCho (PtdCho-IP) and are universally distributed in tissue lipoproteins and cell membranes. Previous work has shown that platelet-activating factor acetylhydrolases (PAF-AH) are the main endogenous PLA2 involved in degradation of PtdCho-IP. The present study shows that the PtdCho-IP are also subject to hydrolysis by group IIA, V and X secretory PLA2, which also have a wide peripheral tissue distribution...
May 20, 2017: Lipids
https://www.readbyqxmd.com/read/28528432/lipid-droplets-formation-to-breakdown
#11
REVIEW
Alex Meyers, Taylor M Weiskittel, Paul Dalhaimer
One of the most exciting areas of cell biology during the last decade has been the study of lipid droplets. Lipid droplets allow cells to store non-polar molecules such as neutral lipids in specific compartments where they are sequestered from the aqueous environment of the cell yet can be accessed through regulated mechanisms. These structures are highly conserved, appearing in organisms throughout the phylogenetic tree. Until somewhat recently, lipid droplets were widely regarded as inert, however progress in the field has continued to demonstrate their vast roles in a number of cellular processes in both mitotic and post-mitotic cells...
May 20, 2017: Lipids
https://www.readbyqxmd.com/read/28523480/2-methoxylated-fa-display-unusual-antibacterial-activity-towards-clinical-isolates-of-methicillin-resistant-staphylococcus-aureus-cimrsa-and-escherichia-coli
#12
Néstor M Carballeira, Nashbly Montano, Christian Morales, Joseph Mooney, Xiomara Torres, Dakeishla Díaz, David J Sanabria-Rios
The naturally occurring (6Z)-(±)-2-methoxy-6-hexadecenoic acid (1) and (6Z)-(±)-2-methoxy-6-octadecenoic acid (2) were synthesized in 7-8 steps with 38 and 13% overall yields, respectively, by using an acetylide coupling approach, which made it possible to obtain a 100% cis-stereochemistry for the double bonds. In a similar fashion, the acetylenic analogs (±)-2-methoxy-6-hexadecynoic acid (3) and (±)-2-methoxy-6-octadecynoic acid (4) were also synthesized in 6-7 steps with 48 and 16% overall yields, respectively...
May 18, 2017: Lipids
https://www.readbyqxmd.com/read/28523479/fatty-acids-have-different-adipogenic-differentiation-potentials-in-stromal-vascular-cells-isolated-from-abdominal-fat-in-laying-hens
#13
Alemu Regassa, Miyoung Suh, Jutika Datar, Chongxiao Chen, Woo Kyun Kim
This study was conducted to examine the effects of fatty acids (FA) with/without chicken serum (CS) on the expression of adipogenic transcripts and adipogenesis in chicken stromal vascular cells (SVC). In experiment 1, SVC were grown in DMEM containing 10% FBS (Control) and treated with 300 µM oleic acid (OLA) + FBS, linoleic acid (LNA) + FBS, palmitic acid (PAM) + FBS, or stearic acid (STA) + FBS for 48 h. In experiment 2, cells were grown in DMEM containing 5% CS and treated with 300 µM OLA (CS + OLA), PAM (CS + PAM), STA (CS + STA) or 200 µM LNA (CS + LNA) for 48 h...
May 18, 2017: Lipids
https://www.readbyqxmd.com/read/28488049/acute-myelogenous-leukemia-cells-secrete-factors-that-stimulate-cellular-ldl-uptake-via-autocrine-and-paracrine-mechanisms
#14
Hasanuzzaman Bhuiyan, Michèle Masquelier, Loukas Tatidis, Astrid Gruber, Christer Paul, Sigurd Vitols
Leukemic cells isolated from most patients with acute myelogenous leukemia (AML) have higher low density lipoprotein (LDL) uptake than normal mononuclear blood cells. Little is known, however, about the mechanism behind the elevated LDL uptake. We investigated if AML cells secrete factors that stimulate cellular LDL uptake. Mononuclear blood cells were isolated from peripheral blood from 42 patients with AML at diagnosis. Cellular LDL uptake was determined from the degradation rate of (125)I-labelled LDL. Conditioned media from AML cells stimulated the LDL degradation in the leukemic cell lines KG1 and HL60, and in isolated AML cells...
May 9, 2017: Lipids
https://www.readbyqxmd.com/read/28474247/inhibition-of-angiotensin-ii-induced-cardiac-fibrosis-by-atorvastatin-in-adiponectin-knockout-mice
#15
Sun Young Choi, Jong Sung Park, Mee Sook Roh, Chong-Rak Kim, Moo Hyun Kim, Victor Serebruany
Adiponectin is a polypeptide known to inhibit cardiac fibrosis via the activation of ‎adenosine monophosphate-activated protein kinase (AMPK). Statins can also activate AMPK, resulting in the secretion of adiponectin. We determined whether atorvastatin inhibits angiotensin II-induced cardiac fibrosis (AICF) in the presence or absence of adiponectin. Adiponectin knockout (APN-KO, n = 44) and wild type (WT, n = 44) mice were received subcutaneous angiotensin II (1.5 mg/kg/day), and atorvastatin (10 mg/kg/day) was administered orally for 15 days...
May 4, 2017: Lipids
https://www.readbyqxmd.com/read/28474246/pectin-penta-oligogalacturonide-suppresses-intestinal-bile-acids-absorption-and-downregulates-the-fxr-fgf15-axis-in-high-cholesterol-fed-mice
#16
Rugang Zhu, Yuting Hou, Yandi Sun, Tuoping Li, Jungang Fan, Gang Chen, Junxiu Wei
Haw pectin penta-oligogalacturonide (HPPS), purified from the hydrolysates of haw pectin, has important role in decreasing hepatic cholesterol accumulation and promoting bile acids (BA) excretion in the feces of mice fed a high-cholesterol diet (HCD). However, the mechanism is not clear. This study aims to investigate the effects of HPPS on BA reabsorption in ileum and biosynthesis in liver of mice. Results showed that HPPS increased fecal BA output by approximately 110%, but decreased ileal BA and the total BA pool size by approximately 47 and 36%, respectively, compared to HCD...
May 4, 2017: Lipids
https://www.readbyqxmd.com/read/28455684/so-you-want-to-publish-in-lipids-tips-for-authors-to-enhance-their-potential-for-success
#17
EDITORIAL
Eric J Murphy
No abstract text is available yet for this article.
April 28, 2017: Lipids
https://www.readbyqxmd.com/read/28439746/plasma-phosphatidylethanolamine-and-triacylglycerol-fatty-acid-concentrations-are-altered-in-major-depressive-disorder-patients-with-seasonal-pattern
#18
Yurika Otoki, Marie Hennebelle, Anthony J Levitt, Kiyotaka Nakagawa, Walter Swardfager, Ameer Y Taha
Disturbances in peripheral and brain lipid metabolism, including the omega-3 fatty acid docosahexaenoic acid (DHA), have been reported in major depressive disorder (MDD). However, these changes have yet to be confirmed in MDD with seasonal pattern (MDD-s), a subtype of recurrent MDD. The present exploratory study quantified plasma plasmalogen and diacyl-phospholipid species, and fatty acids within total phospholipids, cholesteryl esters, triacylglycerols and free fatty acids in non-medicated MDD-s participants (n = 9) during euthymia in summer or fall, and during depression in winter in order to screen for potential high sensitivity lipid biomarkers...
April 24, 2017: Lipids
https://www.readbyqxmd.com/read/28429150/short-term-high-fat-diet-induces-obesity-enhancing-changes-in-mouse-gut-microbiota-that-are-partially-reversed-by-cessation-of-the-high-fat-diet
#19
Yue Shang, Ehsan Khafipour, Hooman Derakhshani, Lindsei K Sarna, Connie W Woo, Yaw L Siow, Karmin O
The gut microbiota is proposed as a "metabolic organ" involved in energy utilization and is associated with obesity. Dietary intervention is one of the approaches for obesity management. Changes in dietary components have significant impacts on host metabolism and gut microbiota. In the present study, we examined the influence of dietary fat intervention on the modification of gut mucosa-associated microbiota profile along with body weight and metabolic parameter changes. Male C57BL/6J mice (6-week old) were fed a low fat diet (10% kcal fat) as a control or a high fat diet (HFD 60% kcal fat) for 7 weeks...
April 20, 2017: Lipids
https://www.readbyqxmd.com/read/28421424/erratum-to-replacement-of-marine-fish-oil-with-de-novo-omega-3-oils-from-transgenic-camelina-sativa-in-feeds-for-gilthead-sea-bream-sparus-aurata-l
#20
Mónica B Betancor, M Sprague, D Montero, S Usher, O Sayanova, P J Campbell, J A Napier, M J Caballero, M Izquierdo, D R Tocher
No abstract text is available yet for this article.
April 18, 2017: Lipids
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