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Scandinavian Journal of Gastroenterology

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https://www.readbyqxmd.com/read/29790800/resolution-of-late-onset-heart-and-liver-failures-after-reversion-of-jejuno-ileal-bypass-a-case-report
#1
Giovanna Pelà, Fabrizio De Rosa, Pierluigi Demola, Antonio Crocamo, Gabriele Missale, Stefano Cecchini, Federico Marchesi, Francesco Visioli, Enrico Maria Silini, Luigi Roncoroni
OBJECTIVES: Jejuno-ileal bypass (JIB) was a kind of bariatric surgery performed from 1960s to 1980s, able to induce sustainable weight loss by creating a surgical short bowel syndrome. MATERIALS AND METHODS: We report a case of an octogenarian woman who underwent in the early eighties this kind of surgery with consequent 40 kg weight loss. After 27 years, she first developed a reversible metabolic cardiomyopathy that began with signs and symptoms of heart failure...
May 23, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29779417/constipation-in-the-elderly-from-northern-sardinia-is-positively-associated-with-depression-malnutrition-and-female-gender
#2
Maria Pina Dore, Giovanni Mario Pes, Stefano Bibbò, Patrizia Tedde, Gabrio Bassotti
OBJECTIVES: Constipation is a common complaint in older adults. The rise in life expectancy may amplify the problem and increase social expenditure. We investigated the major risk factors associated with constipation in a large sample of elderly. METHODS: Outpatients from Northern Sardinia attending a Geriatric Unit between 2001 and 2014 were enrolled. Demographic and anthropometric data, income, education and self-reported bowel function were collected. The presence of constipation was adjusted for cognitive status, assessed by the Mini-Mental State Examination (MMSE) test; single and cumulative illness rating scale (CIRS); current or past symptomatic depression and anxiety measured by the Geriatric Depression Scale (GDS); nutritional status, evaluated using the Mini-Nutritional Assessment (MNA); type and number of different medications used...
May 20, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29779407/association-of-irritable-bowel-syndrome-and-venous-thromboembolism-methodological-and-statistical-issues
#3
Xiaoyan Liu, Kui Liu
No abstract text is available yet for this article.
May 20, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29779403/lipids-glucose-and-iron-metabolic-alterations-in-chronic-hepatitis-c-after-viral-eradication-comparison-of-the-new-direct-acting-antiviral-agents-with-the-old-regimens
#4
Joana Rita Carvalho, José Velosa, Fátima Serejo
BACKGROUND: Hepatitis C virus (HCV) is a unique virus which interacts with cholesterol, iron and insulin metabolism. There is limited data on the effects of direct-acting antiviral agents (DAAs) on metabolic profiles. We aimed at evaluating the behavior of metabolic risk factors of chronically HCV-infected patients after sustained virologic response (SVR), comparing the outcomes with the new DAAs versus the old treatment regimen Peg-interferon ± ribavirin. METHODS: A total of 178 patients who achieved SVR and completed one year of follow-up were prospectively included in this study: group 1 with 105 patients treated with DAAs and group 2 with 73 patients treated with old regimens...
May 20, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29726295/duodenal-neuroendocrine-neoplasms-a-still-poorly-recognized-clinical-entity
#5
Roberta Elisa Rossi, Emanuele Rausa, Federica Cavalcoli, Dario Conte, Sara Massironi
BACKGROUND: Duodenal neuroendocrine neoplasms (dNENs) are rare tumors, which usually show good prognosis. The optimal management of these tumors is still far from being clearly understood because of their rarity and the poor level of knowledge about their natural history. Herein, we have reviewed the literature on dNENs to collect and analyze the current data on epidemiology, diagnosis and management of these rare tumors. METHODS: Bibliographical searches were performed in PubMed, using the following keywords: duodenal neuroendocrine neoplasm; duodenum; gastrinoma; diagnosis; therapy; guidelines...
May 4, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29720023/direct-acting-antiviral-treatment-of-chronic-hepatitis-c-in-denmark-factors-associated-with-and-barriers-to-treatment-initiation
#6
Christina Sølund, Sofie Hallager, Martin S Pedersen, Ulrik Fahnøe, Anja Ernst, Henrik B Krarup, Birgit T Røge, Peer B Christensen, Alex L Laursen, Jan Gerstoft, Erika Bélard, Lone G Madsen, Kristian Schønning, Anders G Pedersen, Jens Bukh, Nina Weis
OBJECTIVES: We describe factors associated with and barriers to initiation of Direct Acting Antiviral (DAA) treatment in patients with chronic hepatitis C, who fulfill national fibrosis treatment guidelines in Denmark. MATERIALS AND METHODS: In this nationwide cohort study, we included patients with chronic hepatitis C from The Danish Database for Hepatitis B and C (DANHEP) who fulfilled fibrosis treatment criteria. Factors associated with treatment initiation and treatment failure were determined by logistic regression analyses...
May 2, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29719998/biologics-and-immunomodulators-for-treating-crohn-s-disease-developing-after-surgery-for-an-initial-diagnosis-of-ulcerative-colitis-a-review-of-current-literature
#7
Abhijeet Yadav, Joshua Foromera, Kenneth R Falchuk, Joseph D Feuerstein
Crohn's Disease (CD) or CD-like (CDL) conditions of the pouch are rare long-term inflammatory complications of patients who were initially diagnosed with ulcerative colitis (UC) who undergo total proctocolectomy with ileo-anal anastomosis (IPAA). There are no societal guidelines nor a consensus on their treatment, resulting in significant challenges for clinicians for their diagnosis and management. It is important to differentiate them from other more common pouch-related complications like pouchitis, cuffitis, irritable pouch syndrome, surgery associated stricture, and fistula...
May 2, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29703095/reproducibility-feasibility-and-validity-of-the-groningen-defecation-and-fecal-continence-questionnaires
#8
Rob J Meinds, Marjolijn E W Timmerman, Maxime M van Meegdenburg, Monika Trzpis, Paul M A Broens
OBJECTIVES: Current questionnaires on defecation disorders are often brief and fail to include questions considering causative factors. Furthermore, adult and pediatric questionnaires differ, which makes it impossible to monitor defecation disorders during the transition from childhood to adulthood. With these points in mind, we developed the Groningen Defecation and Fecal Continence (DeFeC) questionnaire and its pediatric equivalent, the P-DeFeC. The aim of this paper is to introduce the questionnaires and to assess their feasibility, reproducibility and validity...
April 27, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29688802/infliximab-restores-colonic-barrier-to-adherent-invasive-e-coli-in-crohn-s-disease-via-effects-on-epithelial-lipid-rafts
#9
Olena Yakymenko, Ida Schoultz, Elisabeth Gullberg, Magnus Ström, Sven Almer, Conny Wallon, Arthur Wang, Åsa V Keita, Barry J Campbell, Derek M McKay, Johan D Söderholm
OBJECTIVE: Infliximab is important in the therapeutic arsenal of Crohn's disease (CD). However, its effect on mucosal barrier function is not fully understood. Adherent-invasive Escherichia coli (AIEC) are important in CD pathophysiology, but the transmucosal uptake routes are partly unknown. We investigated effects of infliximab on uptake of colon-specific AIEC HM427 across CD colonic mucosa. MATERIALS AND METHODS: Endoscopic biopsies from non-inflamed colon of seven patients with CD, before and after two infliximab infusions, and eight non-inflammation controls, were mounted in Ussing chambers...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29688100/association-of-irritable-bowel-syndrome-and-venous-thromboembolism
#10
Bengt Zöller, Henrik Ohlsson, Rasmus Waehrens, Jan Sundquist, Kristina Sundquist
OBJECTIVE: Inflammatory bowel disease (IBD) is associated with venous thromboembolism (VTE). Whether functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), are associated with VTE has not been determined. This nationwide study aimed to determine the risk of VTE in IBS outpatients in primary and specialist care. DESIGN: We performed two matched case-control studies. Cases (n = 90,502) were individuals in Sweden aged 18-80 years with a first hospital diagnosis of VTE between 2001 and 2010...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29688095/antibiotic-resistance-pattern-of-helicobacter-pylori-strains-isolated-in-italy-during-2010-2016
#11
Giulia Fiorini, Angelo Zullo, Ilaria Maria Saracino, Matteo Pavoni, Dino Vaira
PURPOSE: Bacterial resistance toward the most used antibiotics is increasing in Helicobacter pylori strains worldwide. Emergence of multidrug resistance significantly affects the efficacy of standard therapy regimens. Therefore, monitoring for primary antimicrobial resistance is essential for H. pylori management in clinical practice. METHODOLOGY: H. pylori isolates obtained from patients consecutively observed in a single center were tested for primary resistance by using E-test method...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29688094/temporary-fc-sems-for-type-ii-ercp-related-perforations-a-case-series-from-two-referral-centers-and-review-of-the-literature
#12
Alberto Tringali, Margherita Pizzicanella, Gianluca Andrisani, Marcello Cintolo, Cesare Hassan, Douglas Adler, Lorenzo Dioscoridi, Monica Pandolfi, Massimiliano Mutignani, Francesco Di Matteo
BACKGROUND AND AIM: Some case reports have shown that fully covered self-expandable metal stents (FC-SEMS) are effective in cases of Stapfer Type II perforation as rescue treatment. The aim of the study was to assess the efficacy and safety of temporary placement of FC-SEMS as primary treatment for Type II perforations and review the literature regarding the use of FC-SEMS in this setting. PATIENTS AND METHOD: Retrospective analysis of consecutive patients with Type II perforation treated with immediate placement of FC-SEMS...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29688090/high-and-low-body-mass-index-may-predict-severe-disease-course-in-children-with-inflammatory-bowel-disease
#13
Anat Yerushalmy-Feler, Amir Ben-Tov, Yael Weintraub, Achiya Amir, Tut Galai, Hadar Moran-Lev, Shlomi Cohen
OBJECTIVES: Inflammatory bowel disease (IBD) has been historically associated with underweight and malnutrition. The impact of both underweight and obesity on the clinical course of IBD in adults is controversial. This study described the association between body mass index (BMI) at diagnosis to disease course in children with IBD. METHODS: We reviewed the medical records of children with IBD from the database of the 'Dana-Dwek' Children's Hospital between 2010 and 2016...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29688072/steroid-free-immunosuppression-with-low-dose-tacrolimus-is-safe-and-significantly-reduces-the-incidence-of-new-onset-diabetes-mellitus-following-liver-transplantation
#14
M Castedal, C Skoglund, C Axelson, W Bennet
OBJECTIVES: Corticosteroids (CS) are traditionally used as part of the basal immunosuppression (IS) following liver transplantation (LT) but are known to be associated with an increased risk of new-onset diabetes mellitus (NODM), cardiovascular morbidity and mortality. The aim of this study was to retrospectively compare the incidence of transient as well as persistent NODM, rejection rate and patient- and graft survival between patients receiving steroid-based and steroid-free maintenance IS...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29687730/efficacy-and-tolerability-of-initiating-or-switching-to-infliximab-biosimilar-ct-p13-in-inflammatory-bowel-disease-ibd-a-large-single-centre-experience
#15
Raguprakash Ratnakumaran, Natalie To, David J Gracie, Christian P Selinger, Anthony O'Connor, Tanya Clark, Nicola Carey, Katherine Leigh, Lynsey Bourner, Alexander C Ford, P John Hamlin
OBJECTIVES: Recently, the infliximab biosimilar (CT-P13) received market authorisation for inflammatory bowel disease (IBD), allowing cost benefits when switching to CT-P13. We aim to assess the efficacy and safety of switching from originator infliximab to CT-P13 for new and existing patients. MATERIAL AND METHODS: Treatment response, remission, primary and secondary loss of response rates, and adverse events in patients who initiated infliximab originator in the 12 months pre-switch (n = 53) were compared with the patients who initiated CT-P13 in the 12 months post-switch (n = 69)...
April 24, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29667463/performance-of-protein-induced-by-vitamin-k-absence-or-antagonist-ii-assessed-by-chemiluminescence-enzyme-immunoassay-for-hepatocellular-carcinoma-detection-a-meta-analysis
#16
Gian Paolo Caviglia, Davide Giuseppe Ribaldone, Maria Lorena Abate, Alessia Ciancio, Rinaldo Pellicano, Antonina Smedile, Giorgio Maria Saracco
OBJECTIVES: In the setting of surveillance for hepatocellular carcinoma (HCC) detection, the use of serum biomarkers in addition to ultrasonography (US) is still a matter of debate. Hence, we performed a meta-analysis to evaluate the diagnostic accuracy of protein induced by vitamin K absence or antagonist-II (PIVKA-II) and alpha-fetoprotein (AFP) alone or in combination for HCC detection in patients at risk of tumor development. MATERIALS AND METHODS: We performed a systematic search in PubMed and Scopus database for original articles published in English from 2011 to 2017, investigating the accuracy of PIVKA-II alone or in combination with AFP (reported as area under the curve [AUC]) for HCC detection among patients at risk of tumor development...
April 18, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29644912/amalgamation-of-systemic-inflammatory-response-syndrome-score-with-c-reactive-protein-level-in-evaluating-acute-pancreatitis-severity-in-children
#17
Wei Zheng, Linqian Zhang, Gao Long, Bo Chen, Xiaoli Shu, Mizu Jiang
BACKGROUND AND AIM: Systemic inflammatory response syndrome (SIRS) has to do with how the body reacts to injury. Herein, we analyzed the clinical features of acute pancreatitis (AP) in children with SIRS complication and investigated the role of SIRS score combined with C-reactive protein (CRP) level in assessing AP severity in children. METHODS: This retrospective cohort study involved 111 children hospitalized with AP at the Children's Hospital of Zhejiang University School of Medicine between January 2012 and August 2017...
April 12, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29644909/advanced-ercp-techniques-for-the-extraction-of-complex-biliary-stones-a-single-referral-center-s-12-year-experience
#18
Nicholas G Brown, Joel Camilo, Eric Nordstrom, Roy D Yen, Norio Fukami, Brian C Brauer, Sachin Wani, Stuart K Amateau, Augustin R Attwell, Raj J Shah
OBJECTIVES: Advanced ERCP techniques (AETs) for difficult biliary stones include peroral cholangioscopy (POC) with electrohydraulic/laser lithotripsy (EHL/LL), endoscopic papillary large balloon dilation (EPLBD) and mechanical lithotripsy (ML). We assess the efficacy of AETs. METHODS: A retrospective query for AETs. PRIMARY OUTCOME: Complete duct clearance. Secondary outcome: Complete duct clearance by technique. Statistical Analysis version 9...
April 12, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29619839/psychometric-validation-of-the-stoma-qol-questionnaire-in-a-canadian-cross-sectional-sample-of-colostomy-and-ileostomy-patients
#19
Ernest Lai, Alexander Caston Peterson, Guiping Liu, Ahmer Karimuddin, R Trafford Crump, Jason M Sutherland
OBJECTIVES: The Stoma-QOL questionnaire is a patient-reported outcome (PRO) used to measure quality of life in patients with ileostomy or colostomy. This study assesses the Stoma-QOL's overall and item-level psychometric characteristics in patients with temporary stomas, and whether stoma-related quality of life differs by demographic characteristics. MATERIALS AND METHODS: Analysis of cross-sectional observational PRO data from hospitals in Vancouver, Canada. Patients registered for elective ileostomy or colostomy closure, over the age of 18, and able to read English were eligible for participation...
April 5, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29616839/the-cultivable-bacterial-flora-of-the-esophagus-in-subjects-with-esophagitis
#20
Elisabeth Norder Grusell, Gunnar Dahlén, Magnus Ruth, Henrik Bergquist, Mogens Bove
BACKGROUND: The healthy human esophagus is colonized by bacteria similar to that of the oral mucosa. However, little is known about the microbiome of the esophagus in esophagitis or the possible role of bacteria in the inflammatory response. AIM: To survey bacterial diversity and compare the microbiome of the esophagus in subjects with gastro-esophageal reflux disease (GERD) and eosinophilic esophagitis (EoE). MATERIAL AND METHODS: Seventeen subjects diagnosed with GERD and 10 with EoE underwent endoscopic examination with brush sampling and biopsies from the oral cavity, upper and lower esophagus...
April 4, 2018: Scandinavian Journal of Gastroenterology
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