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Circulation Research

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https://www.readbyqxmd.com/read/30359201/atherosclerosis
#1
Kouji Kobiyama, Klaus Ley
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359200/transcriptome-analysis-reveals-nonfoamy-rather-than-foamy-plaque-macrophages-are-proinflammatory-in-atherosclerotic-murine-models
#2
Kyeongdae Kim, Dahee Shim, Jun Seong Lee, Konstantin Zaitsev, Jesse W Williams, Ki-Wook Kim, Man-Young Jang, Hyung Seok Jang, Tae Jin Yun, Seung Hyun Lee, Won Kee Yoon, Annik Prat, Nabil G Seidah, Jungsoon Choi, Seung-Pyo Lee, Sang-Ho Yoon, Jin Wu Nam, Je Kyung Seong, Goo Taeg Oh, Gwendalyn J Randolph, Maxim N Artyomov, Cheolho Cheong, Jae-Hoon Choi
RATIONALE: Monocyte infiltration into the subintimal space and its intracellular lipid accumulation are the most prominent features of atherosclerosis. To understand the pathophysiology of atherosclerotic disease, we need to understand the characteristics of lipid-laden foamy macrophages in the subintimal space during atherosclerosis. OBJECTIVE: We sought to examine the transcriptomic profiles of foamy and nonfoamy macrophages isolated from atherosclerotic intima...
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359199/vago-splenic-axis-in-signal-transduction-of-remote-ischemic-preconditioning-in-pigs-and-rats
#3
Helmut Raphael Lieder, Petra Kleinbongard, Andreas Skyschally, Helene Hagelschuer, William M Chilian, Gerd Heusch
RATIONALE: The signal transduction of remote ischemic conditioning is still largely unknown. OBJECTIVE: Characterization of neurohumoral signal transfer and vago-splenic axis in remote ischemic preconditioning (RIPC). METHODS AND RESULTS: Anesthetized pigs were subjected to 60 minutes of coronary occlusion and 180 minutes of reperfusion (placebo+ischemia/reperfusion [PLA+I/R]). RIPC was induced by 4×5/5 minutes of hindlimb I/R 90 minutes before coronary occlusion (RIPC+I/R)...
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359198/correction-to-phosphodiesterase-type-3a-regulates-basal-myocardial-contractility-through-interacting-with-sarcoplasmic-reticulum-calcium-atpase-type-2a-signaling-complexes-in-mouse-heart
#4
(no author information available yet)
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359197/correction-to-g-protein-coupled-receptors-in-heart-disease
#5
(no author information available yet)
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359196/correction-to-differential-protein-kinase-c-isoform-regulation-and-increased-constitutive-activity-of-acetylcholine-regulated-potassium-channels-in-atrial-remodeling
#6
(no author information available yet)
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359194/microbiota-derived-trimethylamine
#7
EDITORIAL
Klytaimnistra Kiouptsi, Wolfram Ruf, Christoph Reinhardt
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359193/who-done-it
#8
EDITORIAL
Hanrui Zhang, Muredach P Reilly
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359192/in-pursuit-of-an-atherosclerosis-vaccine
#9
Kuang-Yuh Chyu, Prediman K Shah
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359191/lack-of-cardiac-improvement-after-cardiosphere-derived-cell-transplantation-in-aging-mouse-hearts
#10
Zhen-Ao Zhao, Xinglong Han, Wei Lei, Jingjing Li, Zhuangzhuang Yang, Jie Wu, Mengchao Yao, Xing-Ai Lu, Lingjuan He, Yihuan Chen, Bin Zhou, Shijun Hu
RATIONALE: Aging is one of the most significant risk factors for cardiovascular diseases, and the incidence of myocardial ischemia increases dramatically with age. Some studies have reported that cardiosphere-derived cells (CDCs) could benefit the injured heart. Nevertheless, the convincing evidence on CDC-induced improvement of aging heart is still limited. OBJECTIVE: In this study, we tested whether the CDCs isolated from neonatal mice could benefit cardiac function in aging mice...
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359190/meet-the-first-authors
#11
(no author information available yet)
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359189/cerebral-cavernous-malformations-develop-through-clonal-expansion-of-mutant-endothelial-cells
#12
Matthew R Detter, Daniel A Snellings, Douglas A Marchuk
RATIONALE: Vascular malformations arise in vessels throughout the entire body. Causative genetic mutations have been identified for many of these diseases; however, little is known about the mutant cell lineage within these malformations. OBJECTIVE: We utilize an inducible mouse model of cerebral cavernous malformations (CCMs) coupled with a multicolor fluorescent reporter to visualize the contribution of mutant endothelial cells (ECs) to the malformation. METHODS AND RESULTS: We combined a Ccm3 mouse model with the confetti fluorescent reporter to simultaneously delete Ccm3 and label the mutant EC with 1 of 4 possible colors...
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359188/experimental-to-clinical-coronary-physiology
#13
K Lance Gould
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359187/of-mice-and-men
#14
EDITORIAL
Kenneth M Fish, Justyna Mleczko, Roger J Hajjar
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359186/lisa-dorn
#15
Pam Goldberg-Smith
No abstract text is available yet for this article.
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30359185/microbial-transplantation-with-human-gut-commensals-containing-cutc-is-sufficient-to-transmit-enhanced-platelet-reactivity-and-thrombosis-potential
#16
Sarah M Skye, Weifei Zhu, Kymberleigh A Romano, Chun-Jun Guo, Zeneng Wang, Xun Jia, Jennifer Kirsop, Bridget Haag, Jennifer M Lang, Joseph A DiDonato, W H Wilson Tang, Aldons J Lusis, Federico E Rey, Michael A Fischbach, Stanley L Hazen
RATIONALE: Gut microbes influence cardiovascular disease and thrombosis risks through the production of trimethylamine N-oxide (TMAO). Microbiota-dependent generation of trimethylamine (TMA)-the precursor to TMAO-is rate limiting in the metaorganismal TMAO pathway in most humans and is catalyzed by several distinct microbial choline TMA-lyases, including the proteins encoded by the cutC/D (choline utilization C/D) genes in multiple human commensals. OBJECTIVE: Direct demonstration that the gut microbial cutC gene is sufficient to transmit enhanced platelet reactivity and thrombosis potential in a host via TMA/TMAO generation has not yet been reported...
October 26, 2018: Circulation Research
https://www.readbyqxmd.com/read/30355169/meet-the-first-authors
#17
(no author information available yet)
No abstract text is available yet for this article.
October 12, 2018: Circulation Research
https://www.readbyqxmd.com/read/30355168/distinguishing-cardiomyocyte-division-from-binucleation
#18
EDITORIAL
Zachary A Kadow, James F Martin
No abstract text is available yet for this article.
October 12, 2018: Circulation Research
https://www.readbyqxmd.com/read/30355167/the-microbiome-and-endothelial-function
#19
EDITORIAL
Jhansi L Leslie, Brian H Annex
No abstract text is available yet for this article.
October 12, 2018: Circulation Research
https://www.readbyqxmd.com/read/30355166/basic-cardiovascular-sciences-scientific-sessions-2018
#20
James W McNamara, Kelly M Grimes, Sakthivel Sadayappan
No abstract text is available yet for this article.
October 12, 2018: Circulation Research
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