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Japanese Journal of Ophthalmology

Keiichiro Minami, Kazunori Miyata, Atsushi Otani, Tadatoshi Tokunaga, Shouta Tokuda, Shiro Amano
PURPOSE: To determine steep increase of corneal irregularity induced by advancement of pterygium. METHODS: A total of 456 eyes from 456 consecutive patients with primary pterygia were examined for corneal topography and advancement of pterygium with respect to the corneal diameter. Corneal irregularity induced by the pterygium advancement was evaluated by Fourier harmonic analyses of the topographic data that were modified for a series of analysis diameters from 1 mm to 6 mm...
March 12, 2018: Japanese Journal of Ophthalmology
Kyoko Ishida, Naoya Moroto, Kazuhiro Murata, Tetsuya Yamamoto
The publisher regrets that the original version.
March 12, 2018: Japanese Journal of Ophthalmology
Miri Na, Aeri Yoo
PURPOSE: To evaluate the effectiveness of the orthokeratology (OK) lens slowing myopic progression compared with no intervention in pediatric eyes METHODS: A retrospective review of medical records was performed on 45 monocular myopic subjects 7 to 13 years of age who were treated with monocular ortho-k lens and followed-up for more than 12 months. The monocular myopia in the subjects' eyes was -0.75 to -4.25 D (diopter), and near emmetropia in the contralateral and with-the-rule astigmatism no greater than -1...
March 9, 2018: Japanese Journal of Ophthalmology
Shao-En Chan, Hsi-Kung Kuo, Chia-Ling Tsai, Pei-Chang Wu
PURPOSE: To study the prevalence, type, and progression of astigmatism in primary school children, and its effect on myopic shift. STUDY DESIGN: A prospective study carried out in a primary school in southern Taiwan. METHODS: The study was performed on a subset of children, one year after initial examination. Refractive error measured by cycloplegic autorefraction was the main study outcome. Astigmatism was recorded as negative cylinder form, and we defined clinical significant astigmatism (CSA) as cylinder refraction -1...
March 2, 2018: Japanese Journal of Ophthalmology
Masafumi Hamada, Kishiko Ohkoshi, Keiji Inagaki, Nobuyuki Ebihara, Akira Murakami
In the original publication, the yellow circles in Figures 2a, 2b, 3a and 3b are placed incorrectly. The corrected figures are given in this Erratum.
February 24, 2018: Japanese Journal of Ophthalmology
Yodpong Chantarasorn, Settapong Techalertsuwan, Pongsavit Siripanthong, Anurak Tamerug
PURPOSE: The purpose of this study is to describe a new technique for small-incision scleral fixation of intraocular lens (IOL) using double 10-0 polypropylene sutures, and to report the outcomes of IOL position compared with intrascleral IOL fixation at 12-month follow-up. STUDY DESIGN: A retrospective comparative study. METHOD: This new technique, called double sutured scleral fixated-IOL (DSF-IOL), was created to help with long-term knots strengthening by applying double sutures to each IOL haptic using an augmented Clove-hitch knot instead of the conventional knots tied by single suture...
February 20, 2018: Japanese Journal of Ophthalmology
Ken Hayashi, Motoaki Yoshida, Hiroshi Sasaki, Akira Hirata
PURPOSE: To compare binocular visual function of myopic pseudophakic patients with myopic monovision to patients without monovision. STUDY DESIGN: Randomized comparative study METHODS: Sixty patients were randomized to one of two groups: patients whose refraction was targeted to -2.75 diopters (D) in the dominant eye and -1.75D in the nondominant eye (myopic monovision group), and patients whose refraction was targeted to -2.75D bilaterally (non-monovision group)...
February 20, 2018: Japanese Journal of Ophthalmology
Tomoaki Murakami, Kiyoshi Suzuma, Akihito Uji, Shin Yoshitake, Yoko Dodo, Masahiro Fujimoto, Tatsuya Yoshitake, Yuko Miwa, Nagahisa Yoshimura
PURPOSE: To investigate the association between the characteristics of foveal cystoid spaces and short-term responsiveness to ranibizumab treatment for diabetic macular edema (DME) at 3 months from the initial injection. METHODS: We retrospectively reviewed 66 eyes of 61 patients with center-involved DME who received three consecutive ranibizumab injections and following as-needed administrations. We evaluated the relationship between visual improvement at 3 months and the preoperative optical coherence tomography (OCT) parameters including hyperreflective foci, heterogeneous OCT reflectivity, mean levels of OCT reflectivity and height of foveal cystoid spaces...
February 19, 2018: Japanese Journal of Ophthalmology
Hideo Akiyama, Danjie Li, Yukitoshi Shimoda, Hidetaka Matsumoto, Shoji Kishi
PURPOSE: To describe the relationship between the vitreous and the neovascularization of the disc (NVD) using swept source optical coherence tomography (SS-OCT) and OCT angiography (OCTA). STUDY DESIGN: Retrospective. METHODS: We examined 17 eyes of 11 consecutive patients diagnosed as NVD associated with proliferative diabetic retinopathy (PDR). The location of the NVD feeder or collector vessels were examined by using RTVue XR Avanti. To determine the condition of the posterior vitreous detachment (PVD) and the proliferative tissue of the NVD, we performed 12 mm horizontal and vertical scans through the disc using SS-OCT...
February 19, 2018: Japanese Journal of Ophthalmology
Mihori Kita, Yukiko Fujii, Sachiyo Hama
PURPOSE: To report 4 cases undergoing 25-gauge endoscopic vitrectomy for the treatment of proliferative vitreoretinopathy with severe corneal opacity in which a transpupillary view of the fundus was not possible. STUDY DESIGN: A retrospective interventional case series. METHODS: The main outcomes measured were postoperative anatomic status of the retina and subjective improvement of vision. RESULTS: Postoperative reattachment of the retina and subjective improvement of vision were achieved in all 4 eyes...
February 19, 2018: Japanese Journal of Ophthalmology
Shigeko Yashiro, Takeshi Nishijima, Yuuka Yamamoto, Yumi Sekine, Natsuyo Yoshida-Hata, Tomohiro Iida, Shinichi Oka
PURPOSE: To assess the usefulness of spectral domain optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) findings in cytomegalovirus (CMV) retinitis. STUDY DESIGN: Observational case series. METHODS: Thirteen eyes of 11 human immunodeficiency virus (HIV)-positive patients with CMV retinitis underwent full ophthalmologic examinations, SD-OCT, and 4 eyes of 4 patients underwent FAF. FAF images included short-wavelength autofluorescence (SW-AF) and near-infrared autofluorescence (IR-AF)...
February 14, 2018: Japanese Journal of Ophthalmology
Takeshi Kezuka, Hitoshi Ishikawa
Anti-myelin-oligodendrocyte glycoprotein (MOG) antibody positive optic neuritis has been established as a new subset of optic neuropathy. Anti-MOG antibodies are usually measured by cell-based assay. Patients with anti-MOG antibody positive optic neuritis respond well to steroid therapy, and, while visual acuity outcomes are favorable, significant visual field defects remain. Furthermore, patients who are anti-MOG antibody positive have higher rates of recurrence compared to antibody negative patients. Based on these findings, anti-MOG antibody positive patients with optic neuritis have the characteristics of good visual outcomes, residual visual field defects, and high risk of recurrence...
February 14, 2018: Japanese Journal of Ophthalmology
Megumi Honjo, Hidenobu Tanihara
Rho-associated protein kinase (ROCK), a ubiquitously expressed signaling messenger and downstream effector of Rho, is activated by several bioactive factors in the aqueous humor (AH). Rho-ROCK signaling regulates a wide spectrum of fundamental cellular events, including cell adhesion, motility, proliferation, differentiation, and apoptosis. Previous studies, including our own, found that ROCK inhibitor lowers intraocular pressure (IOP) via a direct effect on the conventional AH outflow pathway, by regulation of contractile properties, fibrotic activity, and permeability of the trabecular meshwork (TM) and Schlemm's canal (SC) tissues, influencing extracellular matrix (ECM) production...
February 14, 2018: Japanese Journal of Ophthalmology
Takehiro Yamashita, Hiroto Terasaki, Naoya Yoshihara, Yuya Kii, Eisuke Uchino, Taiji Sakamoto
PURPOSE: The trajectories of the supratemporal and infratemporal retinal arteries are associated with the position of the nerve fiber layer defects of glaucomatous eyes. However, no reports have thus far been published on changes in the retinal artery trajectory (RA trajectory) along with growth. Thus, the purpose of this study was to investigate the differences in the RA trajectories of elementary and junior high school students and the associations with axial length (AL). STUDY DESIGN: Prospective cross-sectional observational study...
February 13, 2018: Japanese Journal of Ophthalmology
Takashi Ono, Masaharu Iida, Toshihiro Sakisaka, Keiichiro Minami, Kazunori Miyata
PURPOSE: To evaluate the changes in corneal endothelial cell density (ECD) over a 7-year period after laser peripheral iridotomy (LPI) using argon and neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers. STUDY DESIGN: Retrospective case series. METHODS: Eyes that underwent prophylactic LPI using argon and Nd:YAG lasers were followed up for 7 years. Central corneal endothelial cells were observed by use of noncontact specular microscopy preoperatively and at 1 and 7 years postoperatively...
February 6, 2018: Japanese Journal of Ophthalmology
Hidetaka Matsumoto, Takashi Hiroe, Masahiro Morimoto, Kensuke Mimura, Arisa Ito, Hideo Akiyama
PURPOSE: To evaluate the efficacy of intravitreal aflibercept therapy using a treat-and-extend regimen on treatment-naïve pachychoroid neovasculopathy (PNV) and Type 1 neovascular age-related macular degeneration (AMD). METHODS: We retrospectively studied 42 eyes with PNV and 60 eyes with Type 1 neovascular AMD. We assessed best-corrected visual acuity (BCVA), central macular thickness (CMT), central choroidal thickness (CCT), and total number of injections over 2 years...
February 6, 2018: Japanese Journal of Ophthalmology
Shiho Yoshida, Miyuki Murata, Kousuke Noda, Takashi Matsuda, Michiyuki Saito, Wataru Saito, Atsuhiro Kanda, Susumu Ishida
PURPOSE: To investigate the mechanism of soluble vascular adhesion protein-1 (sVAP-1) accumulation induced by vascular endothelial growth factor (VEGF) in the vitreous of patients with diabetic retinopathy (DR). STUDY DESIGN: Experimental. METHODS: Protein levels of sVAP-1 and N epsilon-(hexanoyl)lysine (HEL), an oxidative stress marker, in the vitreous samples from patients with proliferative diabetic retinopathy (PDR) with or without intravitreal bevacizumab (IVB) injection were determined by ELISA...
February 1, 2018: Japanese Journal of Ophthalmology
Eun Hye Jung, Seong-Joon Kim, Young Suk Yu
PURPOSE: To compare the characteristics of intermittent exotropia patients according to their response to the diagnostic monocular occlusion test. STUDY DESIGN: Retrospective study. METHODS: A retrospective review was performed of 141 patients with intermittent exotropia who had taken a monocular occlusion test before surgery. We classified the patients into 3 groups based on the response to monocular occlusion. The increase group was defined as those patients having an increase in deviation of ≥ 5 prism diopters (PD) after monocular occlusion as compared with the maximum measured angle...
January 30, 2018: Japanese Journal of Ophthalmology
Masafumi Hamada, Kishiko Ohkoshi, Keiji Inagaki, Nobuyuki Ebihara, Akira Murakami
PURPOSE: To compare the visualization of microaneurysms (MAs) in patients with diabetic retinopathy (DR) using optical coherence tomography angiography (OCTA) with that using fluorescein angiography (FA). STUDY DESIGN: Prospective, clinical, and experimental. METHODS: This study was a prospective evaluation of imaging technology. Thirty-seven eyes of 33 patients with DR were scanned using an OCTA instrument. The 83 MAs that were confirmed on OCT B-scan and OCT en face images were evaluated using OCTA, and these findings were compared with those evaluated using FA...
January 30, 2018: Japanese Journal of Ophthalmology
Yutaka Imamura, Masahiro Ishida
PURPOSE: To determine the changes in retinal thickness and whether they correlate with the size of the macular hole (MH) after vitrectomy with internal limiting membrane peeling. STUDY DESIGN: Retrospective, interventional case series METHODS: Consecutive patients with an MH and undergoing pars plana vitrectomy with internal limiting membrane peeling were studied. The retinal thicknesses in the inner 4 sectors as defined by the Early Treatment of Diabetic Retinopathy Study were measured using spectral-domain optical coherence tomography (SD-OCT) before and at 2 weeks and 1, 3, 6, and 12 months after the surgery...
January 30, 2018: Japanese Journal of Ophthalmology
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