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Japanese Journal of Ophthalmology

Sumihiro Kawano, Masato Takeuchi, Shiro Tanaka, Takehiro Yamashita, Taiji Sakamoto, Koji Kawakami
PURPOSE: To describe relevant patient demographic characteristics and investigate the influence of known risk factors for late intraocular lens (IOL) dislocation. To explore the associations between these risk factors and the incidence of recurrent IOL dislocation. STUDY DESIGN: Retrospective cohort study. METHODS: This study was performed using Nationwide Diagnostic Procedure Combination data in Japan from April 1, 2008 through July 31, 2016...
November 13, 2018: Japanese Journal of Ophthalmology
Kazuya Yamashita, Shin Hatou, Yuichi Uchino, Kazuo Tsubota, Shigeto Shimmura
PURPOSE: To evaluate the safety and efficacy of lamellar keratoplasty using preserved donor corneas to treat limbal dermoids. STUDY DESIGN: Retrospective study. METHODS: The clinical records of 19 patients with limbal dermoids, who underwent lamellar keratoplasty using preserved corneas that were observed for more than 6 months at the Keio University School of Medicine between January, 2000 and December, 2017, were retrospectively reviewed...
November 12, 2018: Japanese Journal of Ophthalmology
Lalita Gupta, Michael Waisbourd, Carina T Sanvicente, Michael Hsieh, Sheryl S Wizov, Eric E Spaeth, Jesse Richman, George L Spaeth
PURPOSE: To evaluate the test-retest repeatability of a computer-based contrast sensitivity (CS) test, the Spaeth/Richman contrast sensitivity (SPARCS) test, and to determine the effects of age and lens status on CS in normal eyes. STUDY DESIGN: Prospective cross-sectional study. METHODS: The participants were assessed by use of the SPARCS test in each eye 3 times. The first 2 sessions were supervised, while the third was unsupervised. CS was determined for 5 areas of vision (central, superotemporal, superonasal, inferotemporal, and inferonasal) and combined to provide a total score...
November 10, 2018: Japanese Journal of Ophthalmology
Yoshifumi Okamoto, Shohei Morikawa, Fumiki Okamoto, Naoki Inomoto, Hiroto Ishikawa, Tetsuo Ueda, Taiji Sakamoto, Kazuhiko Sugitani, Tetsuro Oshika
PURPOSE: To describe the epidemiology and clinical outcomes of open globe injuries (OGIs) in Japan over 10 years, and examine preoperative factors influencing the visual prognosis after surgery. STUDY DESIGN: Retrospective, observational, multicenter case-series study. METHODS: Patients' data were entered into a computerized database for review and statistical analyses. The following parameters were assessed; age, gender, initial and final visual acuity, duration between onset and surgery, presence of lens in the eye, characteristics of injury, presence of ocular complications, and number of surgeries...
November 8, 2018: Japanese Journal of Ophthalmology
Shunichiro Nakai, Wataru Matsumiya, Otsuka Keiko, Akiko Miki, Makoto Nakamura, Shigeru Honda
PURPOSE: This study was prospectively carried out to clarify the effectiveness of visual and anatomical outcomes under combination therapy of intravitreal aflibercept (IVA) and verteporfin photodynamic therapy (vPDT) in over 24 months. STUDY DESIGN: A single-arm prospective exploratory study. METHODS: Twenty-six eyes of 26 treatment naïve PCV patients were enrolled in this study. The primary outcome measures were the changes in best corrected visual acuity (BCVA) and the complete polyp regression rate...
November 7, 2018: Japanese Journal of Ophthalmology
Rowayda Mohamed Amin, Alaa E Radwan, Mohamed B Goweida, Hesham F El Goweini, Ahmed M Bedda, Wael M Lotfy, Ahmed R H Ahmed
To outline the management of newly identified trematode induced uveitis in pediatric patients STUDY DESIGN: Prospective interventional case series METHODS: Patients with distinctive uveitis were recruited to either receive steroid monotherapy or undergo surgical excision of the inflammatory lesions based on a scoring system. Outcome measures included best corrected visual acuity (BCVA), intraocular inflammatory activity, and incidence of ophthalmic complications RESULTS: 170 patients (174 eyes) were recruited...
November 2, 2018: Japanese Journal of Ophthalmology
Takashi Komizo, Takashi Ono, Akiko Yagi, Kazunori Miyata, Makoto Aihara
PURPOSE: The present study aimed to investigate the effectiveness of adjunctive therapy involving the Rho-associated, coiled-coil-containing protein kinase (ROCK) inhibitor ripasudil in lowering intraocular pressure (IOP) in patients with different subtypes of glaucoma, on the basis of the time of IOP measurement STUDY DESIGN: Retrospective study METHODS: In total, 58 patients who underwent adjunctive therapy with ripasudil at a single institution were included. They were classified into a primary open-angle glaucoma (POAG) group, an exfoliation glaucoma (XFG) group, and a secondary glaucoma associated with uveitis, or steroid glaucoma (SG), group...
October 28, 2018: Japanese Journal of Ophthalmology
Ayaka Yagasaki, Akira Sawada, Yusuke Manabe, Tetsuya Yamamoto
PURPOSE: To determine the clinical features of patients diagnosed with superior segmental optic hypoplasia (SSOH) and to quantitatively compare retinal nerve fiber layer (RNFL) thickness in SSOH eyes, to that in normal subjects. STUDY DESIGN: Retrospective comparative case series. METHODS: We examined the medical charts of 106 eyes of 59 patients with SSOH and 35 eyes of 35 normal subjects as controls. Forty-four of 59 patients had been examined by spectral-domain optical coherence tomography (SD-OCT)...
October 26, 2018: Japanese Journal of Ophthalmology
Shozo Sonoda, Hiroto Terasaki, Naoko Kakiuchi, Hideki Shiihara, Tomonori Sakoguchi, Masatoshi Tomita, Yuki Shinohara, Takehiro Yamashita, Eisuke Uchino, Taiji Sakamoto
PURPOSE: To determine the capabilities of the "Kago-Eye2" software to semi-automatically segment the choroid in the optical coherence tomographic (OCT) images. STUDY DESIGN: A cross-sectional, prospective study of 44 healthy volunteers. METHODS: The Kago-eye2 software was developed to detect the border between Choriocapillaris and Sattler's layer (C-S) and between Sattler's layer and Haller's layer (S-H). The intra- and inter-grader agreements were determined for the segmentations made with semi-automated and manual analysis using the Kago-Eye2 software...
October 24, 2018: Japanese Journal of Ophthalmology
Yuki Morizane, Noriko Morimoto, Atsushi Fujiwara, Ryo Kawasaki, Hidetoshi Yamashita, Yuichiro Ogura, Fumio Shiraga
PURPOSE: To investigate the visual impairment certification status in Japan. STUDY DESIGN: Observational cross-sectional study. METHODS: We asked all welfare offices throughout Japan to submit data concerning age, sex, causative diseases, and visual impairment grades for newly certified visually impaired individuals aged ≥ 18 years in the fiscal year of 2015. The certification was based on criteria of the Act on Welfare of Physically Disabled Persons...
September 25, 2018: Japanese Journal of Ophthalmology
(no author information available yet)
No abstract text is available yet for this article.
November 2018: Japanese Journal of Ophthalmology
Yutaka Yamada, Yoshihiro Takamura, Takehiro Matsumura, Masakazu Morioka, Makoto Gozawa, Masaru Inatani
PURPOSE: To estimate the effect of sub-Tenon's capsule triamcinolone acetonide injection (STTA) combined with panretinal photocoagulation (PRP) using pattern scan laser (PSL) for high risk non-proliferative diabetic retinopathy (NPDR), in terms of the inflammation and the progression of diabetic macular edema (DME). STUDY DESIGN: Retrospective comparative analysis. METHODS: NPDR patients who underwent PRP using PSL with (STTA+PSL group, n=24) or without (PSL group, n=19) pretreatment of STTA were enrolled...
November 2018: Japanese Journal of Ophthalmology
Shin Yeop Oh, Kyung-Ah Park, Sei Yeul Oh
PURPOSE: We investigated the clinical and demographic factors associated with horizontal muscle reoperation due to recurrent esotropia or consecutive exotropia in infantile esotropia. METHODS: One hundred forty-two patients with infantile esotropia who received at least 3 years of follow-up after their first surgery between January 2004 and December 2012 were included in this study. The patients were divided into 2 groups according to the reoperation, and the reoperation group was further subdivided into 2 groups [recurrent esotropia (RET) and consecutive exotropia (CXT)]...
November 2018: Japanese Journal of Ophthalmology
Daisuke Todokoro, Hiroshi Eguchi, Takashi Suzuki, Motoo Suzuki, Haruyuki Nakayama-Imaohji, Tomomi Kuwahara, Takahiro Nomura, Haruyoshi Tomita, Hideo Akiyama
PURPOSE: Enterococcus faecalis causes severe acute endophthalmitis and often leads to poor visual outcomes. Conjunctival bacterial cultures occasionally grow atypical bacteria including E. faecalis, which can potentially contribute to the development of postoperative endophthalmitis. However, the characteristics of these ocular E. faecalis strains are unknown. This study is the first attempt to determine the population characteristics of E. faecalis clinical isolates from eye infections and ocular commensals...
November 2018: Japanese Journal of Ophthalmology
Hideki Shiihara, Shozo Sonoda, Hiroto Terasaki, Naoko Kakiuchi, Yuki Shinohara, Masatoshi Tomita, Taiji Sakamoto
PURPOSE: To develop an automated method to segment the choroidal layers of en face optical coherent tomography (OCT) images by machine learning. STUDY DESIGN: A cross-sectional, prospective study of 276 eyes of 181 healthy subjects. METHODS: OCT en face images of the choroid were obtained every 2.6 μm from the retinal pigment epithelium (RPE) to the chorioscleral border. The images at the start of the choriocapillaris, start of Sattler's layer, and start of Haller's layer were identified, and the image numbers from the RPE line were taken as the teacher data...
November 2018: Japanese Journal of Ophthalmology
Ken Hayashi, Hiroshi Sasaki, Shin-Ichi Manabe, Akira Hirata
PURPOSE: To compare the intraocular pressure (IOP) and wound state immediately after cataract surgery for eyes with a long clear corneal incision (CCI) with those for eyes with a short CCI. STUDY DESIGN: Randomized clinical trial. METHODS: One hundred twenty-eight eyes of 128 patients scheduled for phacoemulsification were randomly assigned to undergo long (≥ 1.75 mm) or short (< 1.75 mm) CCI (2.4-mm wide). IOP was measured using a rebound tonometer preoperatively, at the conclusion of surgery, and at 30 min, 60 min, 120 min, 180 min, and 24 h postoperatively...
November 2018: Japanese Journal of Ophthalmology
Michael Mimouni, Amit Meshi, Igor Vainer, Assaf Gershoni, Tal Koren, Noa Geffen, Arie Y Nemet, Ori Segal
PURPOSE: To evaluate intravitreal bevacizumab every 2 weeks (biweekly) in refractory neovascular age-related macular degeneration (nAMD). STUDY DESIGN: Retrospective study. METHODS: A retrospective study of consecutive nAMD patients unresponsive to monthly intravitreal anti-vascular endothelial growth factor (VEGF) switched to 3-4 biweekly injections. RESULTS: Twenty-seven eyes of patients aged 82.08  ± 6.85 years were included...
November 2018: Japanese Journal of Ophthalmology
Koji Kitazawa, Kanae Kayukawa, Koichi Wakimasu, Tsutomu Inatomi, Osamu Hieda, Kazuhiko Mori, Chie Sotozono, Shigeru Kinoshita
PURPOSE: To investigate the effectiveness of topical non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of cystoid macular edema (CME) post Descemet's stripping automated endothelial keratoplasty (DSAEK). STUDY DESIGN: Retrospective observational study METHODS: In this study of 334 patients who underwent DSAEK at the Baptist Eye Institute, Kyoto, Japan between July 2011 and December 2015, 18 patients with postoperative CME (determined by optical coherence tomography) treated with topical NSAIDs after the onset of CME were included...
November 2018: Japanese Journal of Ophthalmology
Monika Maria Biernat, Jolanta Rusiecka-Ziółkowska, Elżbieta Piątkowska, Iwona Helemejko, Paweł Biernat, Grażyna Gościniak
PURPOSE: Two Demodex species (eyelash mites)-D. folliculorum and D brevis-are believed to be associated with human skin and eye diseases. However, the clinical significance of infection with Demodex species remains controversial. STUDY DESIGN: The aim of this study was to estimate the prevalence of ocular demodicosis in patients with blepharitis as compared with the prevalence in the healthy population in Poland. METHODS: This case-control prospective study was carried out from 2007 to 2016...
November 2018: Japanese Journal of Ophthalmology
Naoki Kusunose, Takahiro Akamine, Yoshiyuki Kobayashi, Shigeo Yoshida, Kenichi Kimoto, Sai Yasukochi, Naoya Matsunaga, Satoru Koyanagi, Shigehiro Ohdo, Toshiaki Kubota
PURPOSE: Clock genes are components of the molecular clock. Their malfunction is thought to increase the risk of numerous diseases, including cancer. Vascular endothelial growth factor (VEGF) has a pivotal role in angiogenesis, and its expression levels are controlled by clock genes in tumor cells. Ophthalmic diseases such as age-related macular degeneration, proliferative diabetic retinopathy, and neovascular glaucoma are also associated with abnormal angiogenesis followed by upregulation of VEGF in the eye...
November 2018: Japanese Journal of Ophthalmology
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