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Hospital Pharmacy

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https://www.readbyqxmd.com/read/29436525/corrigendum
#1
(no author information available yet)
[This corrects the article DOI: 10.1177/0018578717720507.].
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434389/outcomes-from-a-pharmacist-led-proton-pump-inhibitor-stewardship-program-at-a-single-institution
#2
Rebekah A Wahking, Randal L Steele, Rachel E Hanners, Sean M Lockwood, Kelly W Davis
Background: Proton pump inhibitors (PPIs) are effective medications for acid-related disorders; however, they are also overused and may be associated with several adverse effects. A PPI stewardship program was implemented at one institution to combat the overuse of PPIs. Objective: The purpose of this study is to evaluate the effectiveness of an inpatient PPI stewardship program in reducing PPI use, both during hospitalization and upon discharge. Methods: This was a retrospective cohort study of all patients admitted to an internal medicine service at a single institution from March 14, 2016, to August 14, 2016, with an intervention by the PPI stewardship team...
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434388/acute-hepatocellular-jaundice-after-dofetilide-initiation-a-case-report
#3
Patrick Gary Rose, Robert Seabury, Gregory Cwikla
Dofetilide's hepatotoxicity is not well described. In this case report, we describe acute hepatocellular jaundice related to dofetilide use in a 33-year-old male being treated for atrial fibrillation. Both viral and ischemic causes of hepatocellular damage were ruled out as unlikely in this case. This case report outlines a rare yet probable report of idiosyncratic dofetilide-induced liver injury.
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434387/antimicrobial-utilization-pattern-in-pediatric-patients-in-tertiary-care-hospital-eastern-ethiopia-the-need-for-antimicrobial-stewardship
#4
Samuel Girma, Mekonnen Sisay, Getnet Mengistu, Firehiwot Amare, Dumessa Edessa
Background: Antimicrobials are among the most frequently prescribed medications for pediatric patients. However, inappropriate use of them can increase morbidity, mortality, healthcare costs, and largely antimicrobial resistance. This study aims to assess the antimicrobial utilization pattern in the pediatric ward of Hiwot Fana Specialized University Hospital. Methods: Retrospective cross-sectional study was conducted to assess the antimicrobial utilization. In this study, 403 pediatric medical records selected by systematic random sampling were reviewed...
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434386/evaluation-of-the-incidence-of-ibuprofen-administration-in-alcohol-and-opioid-detoxification-patients-with-concomitant-thrombocytopenia
#5
Sheheryar Muhammad, John R Tomko, Laura M Wilson
Purpose: The purpose of this study was to determine the incidence of ibuprofen administration in patients who are undergoing alcohol and opioid detoxification, and have concomitant alcohol-related thrombocytopenia. Methods: This was a single-center, cross-sectional, prospective, observational study. A daily manual review of electronic health records was conducted for patients admitted to the detoxification unit of the hospital. Patients who (1) were of age 18 years or more, (2) were ordered both alcohol and opioid detoxification protocols, and (3) had a platelet count of less than 150 000/µL were included in the study...
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434385/antibiotics-in-development-for-the-treatment-of-resistant-bacterial-disease
#6
Ryan Kidd, Scot Walker
Many bacterial infections can be treated with the use of antibiotics. These medications continue to reduce morbidity and mortality; unfortunately, their use has brought about drug-resistant pathogens that produce difficult-to-treat infections, which require more extreme treatments. New antibiotics are needed to combat this ever-evolving resistance pathogenesis.
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434384/formulary-drug-review-betrixaban
#7
REVIEW
Danial E Baker
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation/medication use evaluation (DUE/MUE) is also provided each month. With a subscription, the monographs are available online to subscribers...
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434383/common-missteps-with-medication-safety-rolling-a-single-dice-ineffective-strategies-and-unexecuted-action-plans
#8
Michael R Cohen
No abstract text is available yet for this article.
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434382/summaries-of-safety-labeling-changes-approved-by-fda-boxed-warnings-highlights-july-september-2017
#9
(no author information available yet)
No abstract text is available yet for this article.
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434381/ismp-adverse-drug-reactions-influenza-vaccine-induced-stevens-johnson-syndrome-vilazodone-induced-nightmares-dabigatran-induced-pustular-eruptions-neurotoxic-and-cardiotoxic-symptoms-after-cannabis-concentrate-exposure-rosuvastatin-induced-skin-eruption
#10
Michael A Mancano
The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers. Write to Dr. Mancano at ISMP, 200 Lakeside Drive, Suite 200, Horsham, PA 19044 (phone: 215-707-4936; e-mail: mmancano@temple.edu). Your report will be published anonymously unless otherwise requested...
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434380/immediate-attention-required-another-shortage
#11
Alfred Adam L'Altrelli, Lindsay Moreland, Marissa Davis, Rachel Marini, J Alex Viehman, Jessica Daley, Greg Wilson
No abstract text is available yet for this article.
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29434379/the-evolving-frontier-of-digital-health-opportunities-for-pharmacists-on-the-horizon
#12
EDITORIAL
Allison Martin, Philip Brummond, Tara Vlasimsky, Aaron Steffenhagen, James Langley, Jason Glowczewski, Anthony Boyd, Melanie Engels, Staci Hermann, Angela Skaff
No abstract text is available yet for this article.
February 2018: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276258/lumbar-spine-surgeries-and-medication-usage-during-hospital-stay-one-center-perspective
#13
Neena K Sharma, Busuyi Olotu, Asha Mathew, Lemuel R Waitman, Rafia Rasu
Background: Pain after spine surgery is usually managed with opioid and nonopioids. The rate of lumbar spine surgeries (LSS) is rising, but current practices on LSS are not known. A current trend in LSS and medication usage by age group is needed to gain a better understanding of how LSS and its pain management vary by age. Objective: The aim of this study was to report current practices of LSS of discectomy, laminectomy, and fusion in patients aged 18 and older and to gain an understanding of medication use for management of LSS...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276257/production-standard-and-stability-of-compounded-del-nido-cardioplegia-solution
#14
Luis M Pereira, Gregory S Matte, Peter Lutz, Alana Arnold, Al Patterson
Background: The del Nido cardioplegia solution (dNCS) was originally developed for pediatric cardiac surgery, being now also used for adult patients. Hospital pharmacies frequently resort to internal dNCS production which has led to an increase in the need for validated parameters for compounding and storage. Objective: This report defines in-house production standards, as well as the stability of dNCS under optimal storage conditions. Methods: All ingredients were sterile and United States Pharmacopeia (USP)/National Formulary (NF) certified...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276256/evaluation-of-insulin-use-and-hypoglycemia-in-hospitalized-elderly-patients
#15
Quyen N Bach, Rod A Gilmore, Melody C Sheffield, W Anthony Hawkins
Background: Routine administration of correctional insulin is no longer recommended as a primary strategy to treat hyperglycemia in hospitalized patients. Studies have demonstrated significant improvement in glycemic control in patients treated with basal and correctional insulin (B+C) versus correctional insulin alone (C). However, the effect of C or B+C on hypoglycemic events is not well understood. Objective: The objective of this study was to investigate the effect of B+C versus C on hypoglycemic events in hospitalized elderly patients...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276255/in-vitro-evaluation-of-eslicarbazepine-delivery-via-enteral-feeding-tubes
#16
Kristin Reindel, Fang Zhao, Susan Hughes, Vivek S Dave
Purpose: The feasibility of preparing an eslicarbazepine acetate suspension using Aptiom tablets for administration via enteral feeding tubes was evaluated. Methods: Eslicarbazepine acetate suspension (40 mg/mL) was prepared using Aptiom tablets after optimizing the tablet crushing methods and the vehicle composition. A stability-indicating high-performance liquid chromatography (HPLC) method was developed to monitor the eslicarbazepine stability in the prepared suspension. Three enteric feeding tubes of various composition and dimensions were evaluated for the delivery of the suspensions...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276254/factors-associated-with-burnout-among-us-hospital-clinical-pharmacy-practitioners-results-of-a-nationwide-pilot-survey
#17
G Morgan Jones, Neil A Roe, Les Louden, Crystal R Tubbs
Background: In health care, burnout has been defined as a psychological process whereby human service professionals attempting to positively impact the lives of others become overwhelmed and frustrated by unforeseen job stressors. Burnout among various physician groups who primarily practice in the hospital setting has been extensively studied; however, no evidence exists regarding burnout among hospital clinical pharmacists. Objective: The aim of this study was to characterize the level of and identify factors independently associated with burnout among clinical pharmacists practicing in an inpatient hospital setting within the United States...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276253/direct-and-indirect-remuneration-fees-the-controversy-continues
#18
Michael Gabay
The Centers for Medicare and Medicaid Services (CMS) initially created direct and indirect remuneration (DIR) fees with the enactment of Medicare Part D in order to track rebates and other price adjustments made to pharmacy benefit managers (PBMs). PBMs have expanded the use of these fees to "claw back" money from pharmacies on already dispensed medications. Community and specialty pharmacies claim these fees are not transparent, hurt patients and taxpayers, and negatively impact their fiscal bottom line, while PBMs assert that these fees actually reduce premiums for patients...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276252/bace-inhibitors-and-tau-protein-targeting-drugs-in-prevention-of-alzheimer-s-disease
#19
Jonathan Orf, Scot Walker
Alzheimer's disease (AD) is a common disease in the United States with almost 10% of people older than 65 suffering from the disease. A few drugs provide some improvement in mental function in mild-to-moderate disease, but no treatments are available to prevent the development of AD. Two new classes of drugs being investigated for the treatment or prevention of AD include drugs to decrease beta amyloid accumulation and Tau protein aggregation inhibitors. After disappointing results for treatment of AD, both classes are being tested in prevention trials...
December 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29276251/formulary-drug-review-edaravone
#20
REVIEW
Zaynah K Ali, Danial E Baker
Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation/medication use evaluation (DUE/MUE) is also provided each month. With a subscription, the monographs are available online to subscribers...
December 2017: Hospital Pharmacy
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