Yan Guo, Drew A Westmoreland, Alexa D'Angelo, Chloe Mirzayi, Michelle Dearolf, Pedro B Carneiro, Meredith Ray, David W Pantalone, Adam W Carrico, Viraj V Patel, Sarit A Golub, Sabina Hirshfield, Donald Hoover, Denis Nash, Christian Grov
In the US, sexual and gender minority populations are disproportionately affected by HIV. Pre-exposure prophylaxis (PrEP) is a key prevention method, but its effectiveness relies on consistent usage. Our four-year national cohort study explored PrEP discontinuation among sexual and gender minority people who initiated PrEP. We found a high annual rate of discontinuation (35-40 percent) after PrEP initiation. Multivariable analysis with 6,410 person-years identified housing instability and prior history of PrEP discontinuation as predictors of discontinuation...
March 2024: Health Affairs