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Nature Reviews. Microbiology

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https://www.readbyqxmd.com/read/30026520/defence-countermeasures
#1
Andrea Du Toit
No abstract text is available yet for this article.
July 19, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/30022105/author-correction-multidrug-efflux-pumps-structure-function-and-regulation
#2
Dijun Du, Xuan Wang-Kan, Arthur Neuberger, Hendrik W van Veen, Klaas M Pos, Laura J V Piddock, Ben F Luisi
In the version of this Review originally published, the author contributions of co-author Arthur Neuberger were incorrectly listed. The author contributions should have appeared as 'D.D., X.W.-K., A.N., H.W.v.V., K.M.P., L.J.V.P. and B.F.L. researched data for the article, made substantial contributions to discussions of the content, wrote the article, and reviewed and edited the manuscript before submission'. This has now been corrected in all versions of the Review. The authors apologize to readers for this error...
July 18, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/30022104/provoking-your-enemies-to-kill-each-other
#3
Ursula Hofer
No abstract text is available yet for this article.
July 18, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/30022103/feast-and-famine-the-keys-to-gut-engraftment
#4
Ursula Hofer
No abstract text is available yet for this article.
July 18, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/30018358/delivery-of-the-gut-microbiome
#5
Ashley York
No abstract text is available yet for this article.
July 17, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/30008469/structural-insights-into-the-signalling-mechanisms-of-two-component-systems
#6
REVIEW
Françoise Jacob-Dubuisson, Ariel Mechaly, Jean-Michel Betton, Rudy Antoine
Two-component systems reprogramme diverse aspects of microbial physiology in response to environmental cues. Canonical systems are composed of a transmembrane sensor histidine kinase and its cognate response regulator. They catalyse three reactions: autophosphorylation of the histidine kinase, transfer of the phosphoryl group to the regulator and dephosphorylation of the phosphoregulator. Elucidating signal transduction between sensor and output domains is highly challenging given the size, flexibility and dynamics of histidine kinases...
July 15, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/30008468/bacterial-adhesion-at-the-single-cell-level
#7
REVIEW
Cecile Berne, Courtney K Ellison, Adrien Ducret, Yves V Brun
The formation of multicellular microbial communities, called biofilms, starts from the adhesion of a few planktonic cells to the surface. The transition from a free-living planktonic lifestyle to a sessile, attached state is a multifactorial process that is determined by biological, chemical and physical properties of the environment, the surface and the bacterial cell. The initial weak, reversible interactions between a bacterium and a surface strengthen to yield irreversible adhesion. In this Review, we summarize our understanding of the mechanisms governing bacterial adhesion at the single-cell level, including the physical forces experienced by a cell before reaching the surface, the first contact with a surface and the transition from reversible to permanent adhesion...
July 15, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/30002505/multidrug-efflux-pumps-structure-function-and-regulation
#8
REVIEW
Dijun Du, Xuan Wang-Kan, Arthur Neuberger, Hendrik W van Veen, Klaas M Pos, Laura J V Piddock, Ben F Luisi
Infections arising from multidrug-resistant pathogenic bacteria are spreading rapidly throughout the world and threaten to become untreatable. The origins of resistance are numerous and complex, but one underlying factor is the capacity of bacteria to rapidly export drugs through the intrinsic activity of efflux pumps. In this Review, we describe recent advances that have increased our understanding of the structures and molecular mechanisms of multidrug efflux pumps in bacteria. Clinical and laboratory data indicate that efflux pumps function not only in the drug extrusion process but also in virulence and the adaptive responses that contribute to antimicrobial resistance during infection...
July 12, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29995832/rna-binding-proteins-in-bacteria
#9
REVIEW
Erik Holmqvist, Jörg Vogel
RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal proteins, studies of bacterial RBPs have paved the way for molecular studies of RNA-protein interactions. Work over the years has identified major RBPs that act on cellular transcripts at the various stages of bacterial gene expression and that enable their integration into post-transcriptional networks that also comprise small non-coding RNAs...
July 11, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29976950/candida-tolerates-and-persists
#10
Ursula Hofer
No abstract text is available yet for this article.
July 5, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29967420/ecology-and-evolution-of-seafloor-and-subseafloor-microbial-communities
#11
REVIEW
William D Orsi
Vast regions of the dark ocean have ultra-slow rates of organic matter sedimentation, and their sediments are oxygenated to great depths yet have low levels of organic matter and cells. Primary production in the oxic seabed is supported by ammonia-oxidizing archaea, whereas in anoxic sediments, novel, uncultivated groups have the potential to produce H2 and CH4 , which fuel anaerobic carbon fixation. Subseafloor bacteria have very low mutation rates, and their evolution is likely dominated by selection of different pre-adapted subseafloor taxa under oxic and anoxic conditions...
July 2, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29946124/cyanobacterial-blooms
#12
REVIEW
Jef Huisman, Geoffrey A Codd, Hans W Paerl, Bas W Ibelings, Jolanda M H Verspagen, Petra M Visser
Cyanobacteria can form dense and sometimes toxic blooms in freshwater and marine environments, which threaten ecosystem functioning and degrade water quality for recreation, drinking water, fisheries and human health. Here, we review evidence indicating that cyanobacterial blooms are increasing in frequency, magnitude and duration globally. We highlight species traits and environmental conditions that enable cyanobacteria to thrive and explain why eutrophication and climate change catalyse the global expansion of cyanobacterial blooms...
June 26, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29946123/gut-microbiota-bile-acid-metabolism-controls-cancer-immunosurveillance
#13
Anna Dart
No abstract text is available yet for this article.
June 26, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29946122/falling-into-your-own-trap
#14
Andrea Du Toit
No abstract text is available yet for this article.
June 26, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29946121/an-aquatic-origin-of-retroviruses
#15
Ashley York
No abstract text is available yet for this article.
June 26, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29930288/surveying-what-s-flushed-away
#16
Gregorio Iraola, Nitin Kumar
No abstract text is available yet for this article.
June 21, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29921914/zika-virus-vaccines
#17
REVIEW
Peter Abbink, Kathryn E Stephenson, Dan H Barouch
The recent epidemic of Zika virus (ZIKV) in the Americas has revealed the devastating consequences of ZIKV infection, particularly in pregnant women. Congenital Zika syndrome, characterized by malformations and microcephaly in neonates as well as developmental challenges in children, highlights the need for the development of a safe and effective vaccine. Multiple vaccine candidates have been developed and have shown promising results in both animal models and phase I clinical trials. However, important challenges remain for the clinical development of these vaccines...
June 19, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29907761/sharing-the-burden-to-build-a-matrix
#18
Ashley York
No abstract text is available yet for this article.
June 15, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29904083/four-is-a-crowd
#19
Andrea Du Toit
No abstract text is available yet for this article.
June 14, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29904082/interactions-of-commensal-and-pathogenic-microorganisms-with-the-intestinal-mucosal-barrier
#20
REVIEW
Eric C Martens, Mareike Neumann, Mahesh S Desai
The intestinal mucosal barrier is composed of epithelial cells that are protected by an overlying host-secreted mucous layer and functions as the first line of defence against pathogenic and non-pathogenic microorganisms. Some microorganisms have evolved strategies to either survive in the mucosal barrier or circumvent it to establish infection. In this Review, we discuss the current state of knowledge of the complex interactions of commensal microorganisms with the intestinal mucosal barrier, and we discuss strategies used by pathogenic microorganisms to establish infection by either exploiting different epithelial cell lineages or disrupting the mucous layer, as well as the role of defects in mucus production in chronic disease...
June 14, 2018: Nature Reviews. Microbiology
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