Jhenifer Nascimento da Silva, Christiano Calixto Conceição, Gisely Cristina Ramos de Brito, Carlos Renato de Oliveira Daumas Filho, Ana Beatriz Walter Nuno, Octavio A C Talyuli, Angélica Arcanjo, Pedro L de Oliveira, Luciano Andrade Moreira, Itabajara da Silva Vaz, Carlos Logullo
Wolbachia pipientis is a maternally transmitted symbiotic bacterium that mainly colonizes arthropods, potentially affecting different aspects of the host's physiology, e.g. reproduction, immunity, and metabolism. It has been shown that Wolbachia modulates glycogen metabolism in mosquito Aedes fluviatilis (Ae. fluviatilis). Glycogen synthesis is controlled by the enzyme GSK3, which is also involved in immune responses in both vertebrate and invertebrate organisms. Here we investigated the mechanisms behind immune changes mediated by GSK3β in the symbiosis between Ae...
April 6, 2024: Journal of Biological Chemistry