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American Journal of Health-system Pharmacy: AJHP

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https://www.readbyqxmd.com/read/29674328/catastrophic-circulatory-collapse-after-inadvertent-subcutaneous-injection-of-treprostinil
#1
John J Radosevich, Mohan Dutt, Jeremy Feldman
PURPOSE: A case of life-threatening cardiovascular collapse after inadvertent subcutaneous injection of undiluted treprostinil is reported. SUMMARY: A 29-year-old, 76-kg woman with group 1 pulmonary arterial hypertension managed with subcutaneous treprostinil infusion arrived at the emergency department (ED) with headache, nausea, vomiting, and a syncopal episode. Her vital signs were stable on presentation. Admission orders were placed, and the appropriate 3-mL syringe containing 7...
April 19, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29674327/incorporating-medication-indications-into-the-prescribing-process
#2
Kevin Kron, Sara Myers, Lynn Volk, Aaron Nathan, Pamela Neri, Alejandra Salazar, Mary G Amato, Adam Wright, Sam Karmiy, Sarah McCord, Enrique Seoane-Vazquez, Tewodros Eguale, Rosa Rodriguez-Monguio, David W Bates, Gordon Schiff
PURPOSE: The incorporation of medication indications into the prescribing process to improve patient safety is discussed. SUMMARY: Currently, most prescriptions lack a key piece of information needed for safe medication use: the patient-specific drug indication. Integrating indications could pave the way for safer prescribing in multiple ways, including avoiding look-alike/sound-alike errors, facilitating selection of drugs of choice, aiding in communication among the healthcare team, bolstering patient understanding and adherence, and organizing medication lists to facilitate medication reconciliation...
April 19, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29654141/advancement-of-clinical-pharmacy-practice-through-intervention-capture
#3
Julie A Groppi, Heather Ourth, Anthony P Morreale, Jennifer M Hirsh, Samantha Wright
PURPOSE: The methods and processes utilized to deploy the Pharmacists Achieve Results with Medications Documentation (PhARMD) Project intervention template across the largest integrated healthcare system in the United States are described. SUMMARY: The PhARMD Project team at the Department of Veterans Affairs (VA) designed, developed, and deployed a standardized template within VA's electronic health record (EHR) that allows the clinical pharmacy specialist (CPS) to efficiently document select interventions made during patient care encounters that specifically contribute to the overall care provided and patient outcomes...
April 13, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29654140/optimization-of-clinical-pharmacy-specialists-at-veterans-affairs-facilities
#4
EDITORIAL
Carolyn Clancy
No abstract text is available yet for this article.
April 13, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29654139/implementation-and-evaluation-of-a-pharmacist-led-electronic-visit-program-for-diabetes-and-anticoagulation-care-in-a-patient-centered-medical-home
#5
Emily M Hawes, Erika Lambert, Alfred Reid, Gretchen Tong, Mark Gwynne
PURPOSE: Results of a study evaluating quality-of-care, financial, and patient satisfaction outcomes of pharmacist-conducted telehealth visits for diabetes management and warfarin monitoring are reported. METHODS: A retrospective pre-post study was conducted to determine the impact of an electronic visit (e-visit) program targeting 2 groups of outpatients: adults with uncontrolled diabetes and warfarin-treated adults performing patient self-testing (PST) for monitoring of International Normalized Ratio (INR) values...
April 13, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29650727/a-pharmacy-led-united-states-pharmacopeia-usp-chapter-800-compliance-collaborative-at-an-academic-medical-center
#6
Bijan C Mekoba, Erin M Turingan, Patricia A Roberts, Susan Mason, Ian Willoughby, Cindy Taylor, Andrew Stivers, John Valgus
PURPOSE: One academic medical center's efforts to move toward compliance with requirements of United States Pharmacopeia ( USP ) chapter 800 through a multidepartmental collaborative initiative are described. SUMMARY: Requirements of USP general chapter 800 (enforceable as of December 2019) address the handling of hazardous drugs (HDs) throughout the entire operational and clinical cycle, from receiving to compounding, administration, and waste disposal. Due to the variety of pharmacy operational areas in which HDs are encountered at University of North Carolina Medical Center (UNCMC), multiple pharmacy managers oversee the safe handling of HDs...
April 12, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29650726/reduction-of-healthcare-costs-through-a-transitions-of-care-program
#7
Weiyi Ni, Danielle Colayco, Jonathan Hashimoto, Kevin Komoto, Chandrakala Gowda, Bruce Wearda, Jeffrey McCombs
PURPOSE: Results of an evaluation of the impact of a pharmacy-based transitional care program on healthcare costs in a population of high-risk patients are reported. METHODS: A nonrandomized, observational cohort study was conducted to compare cost outcomes in a group of patients discharged from a single hospital who were referred to an ambulatory care pharmacy-based transitions-of-care (TOC) program and a control group of patients discharged from neighboring hospitals who received usual care; all patients were members of the same managed Medicaid plan...
April 12, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29626086/former-ashp-vp-dwight-r-tousignaut-dies-at-84
#8
Cheryl A Thompson
No abstract text is available yet for this article.
April 6, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29610290/implementation-and-quality-assessment-of-a-pharmacy-services-call-center-for-outpatient-pharmacies-and-specialty-pharmacy-services-in-an-academic-health-system
#9
Matthew H Rim, Karen C Thomas, Jane Chandramouli, Stephanie A Barrus, Nancy A Nickman
PURPOSE: The implementation and quality assessment of a pharmacy services call center (PSCC) for outpatient pharmacies and specialty pharmacy services within an academic health system are described. SUMMARY: Prolonged wait times in outpatient pharmacies or hold times on the phone affect the ability of pharmacies to capture and retain prescriptions. To support outpatient pharmacy operations and improve quality, a PSCC was developed to centralize handling of all outpatient and specialty pharmacy calls...
April 2, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29555640/ashp-ppag-guidelines-for-providing-pediatric-pharmacy-services-in-hospitals-and-health-systems
#10
Lea S Eiland, Kim Benner, Karl F Gumpper, Melissa K Heigham, Rachel Meyers, Katherine Pham, Amy L Potts
No abstract text is available yet for this article.
March 19, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29467148/controlling-postoperative-use-of-i-v-acetaminophen-at-an-academic-medical-center
#11
William R Vincent, Paul Huiras, Jennifer Empfield, Kevin J Horbowicz, Keith Lewis, David McAneny, David Twitchell
PURPOSE: Results of an interprofessional formulary initiative to decrease postoperative prescribing of i.v. acetaminophen are reported. SUMMARY: After a medical center added i.v. acetaminophen to its formulary, increased prescribing of the i.v. formulation and a 3-fold price increase resulted in monthly spending of more than $40,000, prompting an organizationwide effort to curtail that cost while maintaining effective pain management. The surgery, anesthesia, and pharmacy departments applied the Institute for Healthcare Improvement's Model for Improvement to implement (1) pharmacist-led enforcement of prescribing restrictions, (2) retrospective evaluation of i...
February 21, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29467147/alectinib-for-advanced-alk-positive-non-small-cell-lung-cancer
#12
REVIEW
Ashley C Ly, Jacqueline L Olin, Morgan B Smith
PURPOSE: The pharmacology, pharmacokinetics, clinical efficacy, safety and tolerability, dosage and administration, and place in therapy of alectinib for treatment of patients with non-small-cell lung cancer (NSCLC) are reviewed. SUMMARY: In patients with NSCLC driven by mutations of ALK , the gene coding for anaplastic lymphoma kinase (ALK), treatment with the ALK inhibitor crizotinib has been found to provide median progression-free survival (PFS) of 10.9 months; however, therapeutic failures and tumor progression to brain metastases are common with crizotinib use, prompting research to find more potent and tolerable ALK inhibitors that target major oncogenic drivers of NSCLC...
February 21, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691269/implementation-of-a-pharmacy-managed-program-for-the-transition-of-chemotherapy-to-the-outpatient-setting
#13
Ali McBride, Christopher J Campen, James Camamo, Marie Maloney, Daniel Persky, Sandra E Kurtin, Nikki L Barket, Ravitharan Krishnadasan, Emad Elquza, Faiz Anwer, Kurt Weibel
PURPOSE: Implementation of a pharmacy-managed program for the transition of chemotherapy to the outpatient setting is described. SUMMARY: The University of Arizona Cancer Center and Banner-University Medical Center Tucson are affiliated not-for-profit academic medical centers in Tucson, Arizona, whose facilities include a hospital and ambulatory care clinics that maintain 3 outpatient infusion centers. The cancer center pharmacy currently employs 25 pharmacists, with 4 clinical pharmacists serving both the inpatient and outpatient treatment sites...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691268/stability-of-milrinone-in-continuous-ambulatory-delivery-devices
#14
Farah Al Madfai, Syed Tabish R Zaidi, Long Chiau Ming, Troy Wanandy, Rahul P Patel
PURPOSE: The stability of milrinone in continuous ambulatory delivery devices (CADDs) stored at 4, 25, and 35 °C was evaluated. METHOD: Six CADDs (3 devices containing milrinone plus 0.9% sodium chloride injection and 3 devices containing milrinone plus 5% dextrose injection) were prepared. Devices were kept at 4 °C for 168 hours, followed by 24 hours at 25 °C and an additional 24 hours at 35 °C. Samples ( n = 3) were withdrawn aseptically at 0, 24, 48, 72, 96, 120, 144, and 168 hours from the CADDs stored at 4 °C and at 0, 6, and 24 hours from the CADDs stored at 25 and 35 °C...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691267/stability-of-extemporaneously-prepared-cinacalcet-oral-suspensions
#15
Kara Thomson, David J Hutchinson, Lipika Chablani
PURPOSE: The stability of extemporaneously prepared cinacalcet suspensions over 90 days was evaluated. METHODS: Cinacalcet 5-mg/mL suspension was prepared by triturating 30-mg cinacalcet tablets. Twelve 30-mL batches were prepared with a 1:1 mixture of Ora-Plus and either Ora-Sweet or Ora-Sweet SF (sugar free). Three suspensions of each kind were stored at both room temperature and refrigerated conditions. A 1-mL sample was taken from each bottle at 0, 7, 18, 32, 64, and 90 days...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691266/stability-of-extemporaneously-prepared-ophthalmic-solutions-for-mydriasis
#16
Nicole A Camp, Jennifer T Nadra, Susan E Hughes, Justine M Gilbert, Fang Zhao
PURPOSE: Results of an evaluation of the physical and chemical stability of extemporaneously prepared adult and pediatric ophthalmic solutions containing combinations of phenylephrine, tropicamide, and cyclopentolate are reported. METHODS: A stability study was conducted to help determine the feasibility of innovative formulations to meet an unmet clinical need for combination mydriatic ophthalmic eyedrops. An adult mydriatic ophthalmic solution containing phenylephrine hydrochloride 2...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691265/effects-of-a-pharmacist-driven-intervention-program-on-hospital-readmissions
#17
Mariel T Shull, Leonard E Braitman, Shana D Stites, Angelo DeLuca, Deborah Hauser
PURPOSE: Results of a study to determine whether routine use of a multifaceted medication-focused intervention at a safety-net hospital was feasible and could reduce hospital readmissions in a Medicare fee-for-service population are reported. METHODS: A quality-improvement cohort study of 1,059 admissions of 667 patients at an inner-city hospital was conducted. Patients in the intervention groups received some or all components of the multifaceted "Medication REACH" intervention, with direct pharmacist involvement from admission through postdischarge aftercare...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691264/visual-acuity-literacy-and-unintentional-misuse-of-nonprescription-medications
#18
Rebecca J Mullen, Laura M Curtis, Rachel O'Conor, Marina Serper, Danielle McCarthy, Stacy C Bailey, Ruth M Parker, Michael S Wolf
PURPOSE: Results of a study of associations between visual acuity and the risk of misuse of nonprescription acetaminophen products in a sample of community-dwelling adults are reported. METHODS: In a study involving English-speaking adults at 4 primary care clinics, the potential for misuse of nonprescription acetaminophen products was measured via a functional assessment of product self-dosing and by testing patients' understanding of the risks of concomitant use (i...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691263/evaluation-of-a-one-dose-package-medication-support-system-for-community-based-elderly-patients-and-eldercare-facilities
#19
Ryoji Suzuki, Takashi Hasegawa
PURPOSE: Results of an evaluation of a one-dose package medication support system (ODP-MSS) for medication support and telecare home monitoring of elderly persons are reported. METHODS: ODP-MSS units were provided to 10 elderly patients living at home, with adherence assistance provided by family members or other medication supporters in response to telephone alerts. In addition, ODP-MSS units were installed in 2 group homes. At the end of the designated study periods, device data logs were analyzed, and study participants were interviewed or surveyed regarding the impact of ODP-MSS use...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29691262/predicting-medication-adherence-in-older-hispanic-patients-with-type-2-diabetes
#20
Joshua Caballero, Raymond L Ownby, Robin J Jacobs, Naushira Pandya, Patrick C Hardigan, Lazara C Ricabal
PURPOSE: Potential cognitive and demographic correlates of medication nonadherence in older Hispanic adults with type 2 diabetes were investigated. METHODS: Forty community-dwelling participants 65 years of age or older were recruited. Executive control function (ECF) was assessed using the executive clock drawing task (CLOX 1) test and the 25-item Executive Interview. Self-reported medication adherence was measured on a visual analog scale (VAS); measures of glycemic control included glycosylated hemoglobin (HbA1c ) concentration...
May 1, 2018: American Journal of Health-system Pharmacy: AJHP
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