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Journal of the American Pharmacists Association: JAPhA

Saul Shiffman, Deena R Battista, Judith P Kelly, Mary K Malone, Rachel B Weinstein, David W Kaufman
OBJECTIVES: To assess whether there are differences in the likelihood of exceeding the daily limit of 4 grams of acetaminophen when using different formulations (325 mg, 500 mg, 650 mg) of OTC single-ingredient (SI) acetaminophen medications. DESIGN AND SETTING: Multiyear observational study of acetaminophen use via daily online acetaminophen-usage diaries completed for 7 days. PARTICIPANTS: A total of 7579 U.S. adults from online research panels who used acetaminophen in the month preceding enrollment and used an OTC SI acetaminophen medication during the study...
July 17, 2018: Journal of the American Pharmacists Association: JAPhA
Kirbee Johnston, Lindsey Alley, Kevin Novak, Sarah Haverly, Adriane Irwin, Daniel Hartung
OBJECTIVE: While literature on pharmacists' engagement with prescription drug monitoring programs (PDMPs) is growing, no formal synthesis of findings has been conducted to provide overarching recommendations for research or practice. The objective of this study was to identify and synthesize findings from current literature on community pharmacists' attitudes toward, knowledge of, and registration and utilization behaviors regarding PDMPs. DATA SOURCES: Electronic databases (MEDLINE, PsychINFO, Cochrane Database of Systematic Reviews, Google Scholar, and the Brandeis University PDMP Center of Excellence) and reference lists from relevant manuscripts were searched for relevant English-language manuscripts...
July 17, 2018: Journal of the American Pharmacists Association: JAPhA
Delesha M Carpenter, Jill E Lavigne, Courtney A Roberts, Jessica Zacher, Evan W Colmenares
OBJECTIVES: The availability of suicide prevention training programs for pharmacists is unknown and may depend on state training requirements. This study's objectives were to: 1) report state training requirements for pharmacist suicide education; and 2) describe educational resources that are available to prepare pharmacists for interactions with patients at risk of suicide. METHODS: Each state's board of pharmacy was contacted from July to November 2017 to determine whether that state required pharmacists to complete suicide prevention training...
July 15, 2018: Journal of the American Pharmacists Association: JAPhA
Christine D Jones, Amanda Anthony, Matthew D Klein, Courtney Shakowski, Holly K Smith, Amy Go, Katharine Perica, Hemali Patel, Jonathan Pell, Read Pierce
OBJECTIVES: To evaluate the feasibility and effect of a pharmacist-led transitions-of-care (TOC) pilot targeted to patients at high risk of readmission on process measures, hospital readmissions, and emergency department (ED) visits. SETTING: Academic medical center in Colorado. PRACTICE DESCRIPTION: Pharmacists enrolled patients identified as high risk for readmission in a TOC pilot from July 2014 to July 2015. The pilot included medication reconciliation, medication counseling, case management or social work evaluation, a postdischarge telephone call, and an expedited primary care follow-up appointment...
July 15, 2018: Journal of the American Pharmacists Association: JAPhA
Luiza Kerstenetzky, Kristina M Heimerl, Katherine J Hartkopf, David R Hager
OBJECTIVES: To evaluate the impact of a pharmacist screening and automated referral process that identifies patients at risk for readmission due to medication-related problems (MRPs). SETTING: University of Wisconsin (UW) Hospital is 505-bed flagship hospital that is part of UW Health, an academic health system. PRACTICE DESCRIPTION: The integrated pharmacy practice model at UW Health has inpatient pharmacists who perform discharge medication reconciliation...
July 15, 2018: Journal of the American Pharmacists Association: JAPhA
Ori Liran, Judit Prus, Noa Gordon, Vered Almog, Tsipora Gruenewald, Daniel A Goldstein
OBJECTIVES: A recent theoretical economic model suggested that oversized vials of cancer drugs lead to $1.8 billion of drug wastage annually in the United States. It is currently unknown how precisely this theoretical model is consistent with the real world. We performed a real-world analysis to assess the economic impact of drug wastage. METHODS: We performed a systematic examination of the usage and wastage of all intravenous cancer drugs in the cancer center of a large tertiary care hospital in Israel...
July 12, 2018: Journal of the American Pharmacists Association: JAPhA
Lisa Blanchette, Timothy Gauthier, Emily Heil, Michael Klepser, Karl Madaras Kelly, Michael Nailor, Wenjing Wei, Katie Suda
OBJECTIVES: The objective of this position statement is to describe the essential role of pharmacists in antimicrobial stewardship in outpatient care. DATA SOURCES: N/A. SUMMARY: The majority of antibiotic prescribing occurs in outpatient care settings highlighting the need for antibiotic stewardship in the community. Given their expertise on medication management, pharmacists are essential to any antibiotic stewardship effort. CONCLUSION: As the regulations for antibiotic stewardship in outpatient settings continue to evolve and optimal stewardship strategies are defined, pharmacists must be leaders in the implementation of these programs...
July 12, 2018: Journal of the American Pharmacists Association: JAPhA
Zachary McCormack
OBJECTIVES: This analysis sought to quantify voting behavior and other characteristics of advisory committee (AC) meetings and compare that with the U.S. Food and Drug Administration's (FDA) approval decisions from 2010 to 2015. METHODS: The analysis of the Center for Drug Evaluation and Research AC meetings was conducted using publicly available information from the FDA website and the sponsors' websites. RESULTS: There were 163 voting sessions, 207 votes, and 229 meetings...
July 10, 2018: Journal of the American Pharmacists Association: JAPhA
Chelsea Phillips Renfro, Michael Patti, Jordan M Ballou, Stefanie P Ferreri
OBJECTIVES: To develop a common language for the medication synchronization process in community pharmacies. METHODS: A systematic and iterative process was used to create and refine a common language for medication synchronization. First, a review of all available medication synchronization-related documents was completed. Second, a systematic scoping literature review was conducted to determine what core components of medication synchronization have been implemented by community pharmacies...
July 3, 2018: Journal of the American Pharmacists Association: JAPhA
Chasity M Shelton, Morgan D Gray, Catherine M Crill
No abstract text is available yet for this article.
June 25, 2018: Journal of the American Pharmacists Association: JAPhA
Daniel A Hussar, Rachel C Boardman
No abstract text is available yet for this article.
June 25, 2018: Journal of the American Pharmacists Association: JAPhA
Spencer H Durham, Elizabeth W Covington, Kimberley J Clemmons
OBJECTIVES: To report a case of hepatotoxicity when niacin was used by a patient with HIV to pass a drug test. METHODS: Niacin is a soluble pyridine derivative widely used in the management of dyslipidemia. Common adverse effects include flushing, nausea, gastrointestinal discomfort, and hepatotoxicity. The use of niacin for nonmedical purposes has been increasing in prevalence in recent years, particularly in attempts to alter or mask results of urine drug tests...
June 22, 2018: Journal of the American Pharmacists Association: JAPhA
T Joseph Mattingly
No abstract text is available yet for this article.
June 14, 2018: Journal of the American Pharmacists Association: JAPhA
Gabriella M Pepe, Tana N Kaefer, Jean-Venable Kelly R Goode
OBJECTIVES: To characterize the most common medication-related problems and interventions and to evaluate the acceptance rates of pharmacist identification of medication-related problems through percent acceptance rates of interventions in a nontraditional long-term care pharmacy. METHODS: A retrospective chart review of long-term care pharmacy patients 18 years of age or older was used to evaluate pharmacist interventions from January 2014 to August 2016. Data collection included the date and type of intervention, patient demographic information (age, sex), drug class involved, physician provider type (primary care or specialist), intervention outcome, and resolution type...
May 30, 2018: Journal of the American Pharmacists Association: JAPhA
Dave L Dixon, Teresa M Salgado, Lauren M Caldas, Benjamin W Van Tassell, Evan M Sisson
OBJECTIVES: To initiate a call to action for community pharmacists to maximize the opportunities to improve the management of hypertension (HTN) in light of the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) HTN guideline. SUMMARY: In November 2017, the ACC and the AHA, along with 9 other professional organizations, released a comprehensive guideline on the prevention, detection, evaluation, and management of high blood pressure (BP)...
May 24, 2018: Journal of the American Pharmacists Association: JAPhA
Judith M Turner, Elizabeth J Unni, Jennifer Strohecker, Jacob Henrichs
OBJECTIVES: Insulin glargine, one of the most commonly prescribed drugs for diabetes, has a 28-day limit on the use of a 10-mL (1000 units) multiple-dose vial once the bottle is punctured. If patients who are using smaller doses or are not adherent continue to use insulin glargine beyond the 28-day window, it can result in questionable stability and sterility of the product. The aim of this study was to determine the proportion of patients who used each insulin glargine vial for more than 28 days, the mean number of days the vial was used after 28 days, the reason for the extended use, and whether that use had any association with diabetes control and injection site infection...
May 22, 2018: Journal of the American Pharmacists Association: JAPhA
Olihe Okoro, Lisa Hillman
OBJECTIVES: The study objectives were to a) assess knowledge and experience; b) describe perceptions and attitudes; and c) identify training needs of community-based pharmacists regarding HIV pre-exposure prophylaxis (PrEP). DESIGN: This was a cross-sectional survey study. SETTING AND PARTICIPANTS: The survey was administered online to pharmacists practicing in a community setting in the state of Minnesota. OUTCOME MEASURES: Measures included knowledge of and experience with HIV PrEP, perceptions and attitudes towards pharmacists' involvement, and HIV PrEP-specific training needs for pharmacists...
May 19, 2018: Journal of the American Pharmacists Association: JAPhA
Karen Suchanek Hudmon, Robin L Corelli, Carl de Moor, Alan J Zillich, Christine Fenlon, Lyndsay Miles, Alexander V Prokhorov, Susan M Zbikowski
OBJECTIVES: To evaluate the long-term impact of 2 promising intervention approaches to engage pharmacy personnel (pharmacists, technicians) in referring patients who want to quit smoking to the tobacco quitline. DESIGN: Randomized trial. SETTING: Community pharmacies in Connecticut (n = 32) and Washington (n = 32). INTERVENTION: Two intervention approaches were evaluated: academic detailing (AD), which involved on-site training for pharmacy staff about the quitline, versus mailed quitline materials (MM)...
May 17, 2018: Journal of the American Pharmacists Association: JAPhA
James L Lin, Jennifer L Bacci, Marci J Reynolds, Yushi Li, Rachel G Firebaugh, Peggy S Odegard
OBJECTIVE: To compare the impact of a whole-staff training strategy to a train-the-trainer strategy on 1) the number of influenza, pneumococcal, herpes zoster, and pertussis vaccines administered by community pharmacists to adults; 2) staff confidence; and 3) fidelity to the intervention. SETTING: Eight Quality Food Centers (QFC) Pharmacies in Seattle, Washington. PRACTICE DESCRIPTION: QFC Pharmacy is a grocery store division of The Kroger Co...
May 9, 2018: Journal of the American Pharmacists Association: JAPhA
Aaron Kovacik, Paula C Bell, Sean King, Amy Mallon, James Renfroe, Charles Dyer
OBJECTIVES: In an effort to reduce reimbursement penalty from the Centers for Medicare and Medicaid Services, hospitals have looked to evaluate the effectiveness of existing programs as well as adopt innovative practices to reduce 30-day readmission rates. The objective of this study was to evaluate the impact of delaying prescription fill on 30-day readmission rates for patients with heart failure (HF) and chronic obstructive pulmonary disease (COPD). Identifying an association between delaying prescription fill and readmission rate would validate programs that provide patients with their medications before discharge...
May 9, 2018: Journal of the American Pharmacists Association: JAPhA
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