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Annals of Pharmacotherapy

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https://www.readbyqxmd.com/read/29932006/semaglutide-the-newest-once-weekly-glp-1-ra-for-type-2-diabetes
#1
Rhianna M Tuchscherer, Angela M Thompson, Jennifer M Trujillo
OBJECTIVE: To review efficacy and safety of the glucagon-like peptide-1 receptor agonist (GLP-1 RA) semaglutide for type 2 diabetes (T2D). DATA SOURCES: A literature search of PubMed/MEDLINE and EMBASE using the term semaglutide was completed through April 2018. A search of clinicaltrials.gov was also conducted. STUDY SELECTION AND DATA EXTRACTION: English-language studies assessing the efficacy and/or safety of semaglutide were evaluated...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29923419/prospective-validation-of-a-risk-prediction-model-to-identify-high-risk-patients-for-medication-errors-at-hospital-admission
#2
Marieke M Ebbens, Sylvia A van Laar, Elsbeth J Wesselink, Kim B Gombert-Handoko, Patricia M L A van den Bemt
BACKGROUND: Pharmacy-led medication reconciliation in elective surgery patients is often performed at the preoperative screening (POS). Because of the time lag between POS and admission, changes in medication may lead to medication errors at admission (MEAs). In a previous study, a risk prediction model for MEA was developed. OBJECTIVE: To validate this risk prediction model to identify patients at risk for MEAs in a university hospital setting. METHODS: The risk prediction model was derived from a cohort of a Dutch general hospital and validated within a comparable cohort from a Dutch University Medical Centre...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29923415/%C3%AE-lactams-the-competing-priorities-of-nephrotoxicity-neurotoxicity-and-stewardship
#3
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29911395/rhabdomyolysis-with-abiraterone-exposure-a-brief-review-of-the-food-and-drug-administration-adverse-event-reporting-system-faers
#4
Donald C Moore, J Tanner Ringley
No abstract text is available yet for this article.
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29911393/renal-and-cardiac-implications-of-sodium-glucose-cotransporter-2-sglt2-inhibitors-the-state-of-the-science
#5
Joseph E Cruz, Tania Ahuja, Mary Barna Bridgeman
OBJECTIVE: To review the role of the sodium-glucose cotransporter-2 (SGLT2) inhibitors in the management of type 2 diabetes (T2DM), including the effects on renal and cardiovascular (CV) outcomes. DATA SOURCES: A literature search of MEDLINE databases (1964 through May 2018) was conducted utilizing key words sodium-glucose co-transporter-2 inhibitors, SGLT2 inhibitors, and diabetes; additional limits for drug names were added. STUDY SELECTION AND DATA EXTRACTION: Available English-language data from reviews, abstracts, presentations, and clinical trials of use of SGLT2 therapy specifically detailing outcomes on CV and renal disease in humans were reviewed...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29911390/incidence-and-risk-factors-for-development-of-thrombocytopenia-in-patients-treated-with-linezolid-for-7-days-or-greater
#6
Alyssa D Rabon, Jon P Fisher, Shawn H MacVane
No abstract text is available yet for this article.
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29909647/pharmacokinetic-differences-between-cobicistat-and-ritonavir-on-warfarin
#7
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29890848/inhaled-epoprostenol-through-noninvasive-routes-of-ventilator-support-systems
#8
Mahmoud A Ammar, Madhu Sasidhar, Simon W Lam
BACKGROUND: The administration of inhaled epoprostenol (iEPO) through noninvasive routes of ventilator support systems has never been previously evaluated. OBJECTIVE: Describe the use of iEPO when administered through noninvasive routes of ventilator support systems. METHODS: Critically ill patients admitted to the intensive care unit who received iEPO through noninvasive routes were analyzed. Improvements in respiratory status and hemodynamic parameters were evaluated...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29890846/evidence-based-best-practices-for-outpatient-management-of-warfarin
#9
Adam J Rose, Mary Vaiana
Many best practices have been described for organizing a clinic to manage warfarin. Although these practices may have face validity, they may not be based on empirical analysis. Here, we describe our decade-long effort to apply the Structure-Process-Outcome model of quality measurement as a basis for measuring and improving outpatient warfarin management in the Veterans Health Administration. The purpose of the article is to raise awareness of this body of work with pharmacists who could potentially incorporate the findings of this work into their own practice settings...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29890845/a-case-of-acute-kidney-injury-associated-with-dabrafenib-and-trametinib-treatment-for-metastatic-melanoma
#10
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29890842/acetazolamide-induced-sickle-cell-crisis
#11
(no author information available yet)
No abstract text is available yet for this article.
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29888615/drug-therapy-problem-severity-following-hospitalization-and-association-with-30-day-clinical-outcomes
#12
Sarah M Westberg, Angela Yarbrough, Eric D Weinhandl, Terrence J Adam, Amanda R Brummel, Shannon L Reidt, Brian T Sick, Wendy L St Peter
BACKGROUND: Improved understanding of how drug therapy problems (DTPs) contribute to rehospitalization is needed. OBJECTIVE: The primary objectives were to assess the association of DTP likelihood of harm (LoH) severity score, as measured by comprehensive medication management (CMM) pharmacist after hospital discharge, with 30-day risk of hospital readmission, observation visit, or emergency department visit, and to determine whether resolution of DTPs reduces 30-day risk...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29871511/impact-of-a-bilingual-pharmacy-diabetes-service-in-a-federally-qualified-health-center
#13
Benjamin Chavez, Emily Kosirog, Jason M Brunner
BACKGROUND: Diabetes and its complications disproportionately affect Hispanic patients, many of whom receive care at federally qualified health centers (FQHCs) and prefer to receive care in a language other than English. There is little published data on clinical pharmacy diabetes services in this setting. OBJECTIVE: This study aims to measure the impact of a Collaborative Drug Therapy Management-driven bilingual clinical pharmacy service on diabetes outcomes in an FQHC that primarily serves Hispanic patients, many of whom prefer to receive their care in Spanish...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29871510/safety-and-efficacy-of-apixaban-versus-warfarin-in-patients-with-advanced-chronic-kidney-disease
#14
Joseph H Schafer, Ashley L Casey, Kristina A Dupre, Britta A Staubes
BACKGROUND: Because of a lack of comparative data on anticoagulant use in the advanced chronic kidney disease (CKD) population, guidelines recommend warfarin for atrial fibrillation and venous thromboembolism (VTE) treatment in these patients. However, apixaban has specific dosing recommendations in CKD leading to use in clinical practice. OBJECTIVE: To evaluate major bleeding, stroke, and thromboembolism rates in patients with CKD stage 4, stage 5, and dialysis on apixaban or warfarin therapy...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29871503/evaluation-of-thrombocytopenia-in-critically-ill-patients-receiving-continuous-renal-replacement-therapy
#15
Christopher A Droege, Neil E Ernst, Nicholas J Messinger, Allison M Burns, Eric W Mueller
BACKGROUND: Continuous renal replacement therapy (CRRT) may be associated with thrombocytopenia in critically ill patients. A confounding factor is concomitant use of unfractionated heparin (UFH) and suspicion for heparin-induced thrombocytopenia (HIT). OBJECTIVE: To determine the impact of CRRT on platelet count and development of thrombocytopenia. METHODS: Retrospective analyses evaluated the intrapatient change in platelet count following CRRT initiation...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29857782/skin-hypersensitivity-to-oral-budesonide-case-report-and-review-of-the-fda-adverse-event-reporting-system-database
#16
Amichai Perlman, Alexander Maly, Zvi Ackerman
No abstract text is available yet for this article.
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29857777/evaluation-of-same-tt-2-r-2-score-on-predicting-success-with-extended-interval-warfarin-monitoring
#17
Andrew Y Hwang, Nicholas W Carris, Eric A Dietrich, John G Gums, Steven M Smith
BACKGROUND: In patients with stable international normalized ratios, 12-week extended-interval warfarin monitoring can be considered; however, predictors of success with this strategy are unknown. The previously validated SAMe-TT2 R2 score (considering sex, age, medical history, treatment, tobacco, and race) predicts anticoagulation control during standard follow-up (every 4 weeks), with lower scores associated with greater time in therapeutic range. OBJECTIVE: To evaluate the ability of the SAMe-TT2 R2 score in predicting success with extended-interval warfarin follow-up in patients with previously stable warfarin doses...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29857773/smoking-cessation-following-text-message-intervention-in-pregnant-women
#18
Alicia B Forinash, Abigail Yancey, Danielle Chamness, Jamie Koerner, Christina Inteso, Collin Miller, Gilad Gross, Katherine Mathews
BACKGROUND: Smoking during pregnancy has detrimental effects on mother and fetus. Text messaging has been utilized to improve patient care. OBJECTIVE: To evaluate the impact of text messaging on smoking cessation rates among pregnant women in addition to standard of care (SOC) smoking cessation services. Our SOC includes pharmacist-driven education with or without nicotine patch or bupropion. METHODS: This randomized, open-label, prospective trial was conducted at a maternal fetal care center from May 2014 to January 2016...
June 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29808711/effect-of-a-structured-pharmaceutical-care-intervention-versus-usual-care-on-cardiovascular-risk-in-hiv-patients-on-antiretroviral-therapy-infamerica-study
#19
Ramón Morillo-Verdugo, María de Las Aguas Robustillo-Cortés, María Teresa Martín-Conde, Gador Callejón-Callejón, Purificación Cid-Silva, Carmen Moriel-Sánchez, Begoña Tortajada-Goitia, Carmen Victoria Almeida-González
BACKGROUND: HIV+ patients have increased their life expectancy with a parallel increase in age-associated comorbidities. OBJECTIVE: To determine the effectiveness of an intensive pharmaceutical care follow-up program in comparison to a traditional model among HIV-infected patients with moderate/high cardiovascular risk. METHOD: This was a multicenter, prospective, randomized study of a structured health intervention conducted between January-2014 and June-2015 with 12 months of follow-up at outpatient pharmacy services...
May 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29808707/a-review-of-ace-inhibitors-and-arbs-in-black-patients-with-hypertension
#20
Allison Helmer, Nicole Slater, Sean Smithgall
OBJECTIVE: To review current guidelines and recent data evaluating the efficacy and safety of angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) in black hypertensive patients. DATA SOURCES: Articles evaluating race-specific outcomes in hypertension were gathered using a MEDLINE search with keywords black, African American, ACE inhibitor, angiotensin receptor blocker, angiotensin system, and hypertension. Studies published from 2000 through April 2018 were reviewed...
May 1, 2018: Annals of Pharmacotherapy
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